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2022

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The Effect Of High Dose Ascorbic Acid And High Dcad Administration On Oxidative Stress And Mammary Gland Function Of Dairy Goat Fed Under Tropical Condition, Sapon Semsirmboon Jan 2022

The Effect Of High Dose Ascorbic Acid And High Dcad Administration On Oxidative Stress And Mammary Gland Function Of Dairy Goat Fed Under Tropical Condition, Sapon Semsirmboon

Chulalongkorn University Theses and Dissertations (Chula ETD)

High ambient temperature (HTa) increased the respiration rate (RR) and rectal temperature (Tr) of dairy goats. The excess response resulted in acid-base imbalance, electrolyte imbalance, and systemic oxidative which could indirectly affect the mammary gland. Besides, HTa did directly alter cell function, and this has been proposed to be mediated by oxidative stress. We previously showed that high dietary cation and anion differences (DCAD) could decrease the HTa effect. In dairy cows, a high dose ascorbic acid (Asc) has been used to decrease oxidative stress. Then, It was hypothesized whether mammary gland function could be altered when the HTa was …

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Effects Of Fingerroot (Boesenbergia Rotunda) Powder On Egg Performance, And Quality, Egg Yolk Malondialdehyde In Laying Hens, Miftah Nurfarid Jan 2022

Effects Of Fingerroot (Boesenbergia Rotunda) Powder On Egg Performance, And Quality, Egg Yolk Malondialdehyde In Laying Hens, Miftah Nurfarid

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study aimed to determine the effect of fingerroot powder supplementation on the performance of laying hens, egg quality, and malondialdehyde in the egg yolk. A total of 192 Hy-Line brown laying hens aged 43 weeks were divided into four treatment groups with 48 hens in each group (8 replicates; 6 birds each). The treatments were the control (basal diet), basal diet supplemented with vitamin E at 250 mg/kg, basal diet plus 20 g fingerroot powder/kg, and basal diet plus 40 g fingerroot powder/kg. Performance parameters were analyzed in the following two experimental period: 1 to 3 week and 4 …

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Microencapsulation Of Basil Oil And Its Effect On Replacement Of Antibiotic Growth Promoter, Antioxidant Status And Gut Functions Of Broilers, Sureerat Thuekeaw Jan 2022

Microencapsulation Of Basil Oil And Its Effect On Replacement Of Antibiotic Growth Promoter, Antioxidant Status And Gut Functions Of Broilers, Sureerat Thuekeaw

Chulalongkorn University Theses and Dissertations (Chula ETD)

The objectives of this work were 1) to study the preparation and characterization of microencapsulated basil oil (MBO), 2) to determine the stability of MBO against simulated gastrointestinal tract and storage 3) to investigate the antimicrobial and antioxidant properties of MBO and 4) to evaluate the supplementation of MBO on growth performance, antioxidant status, ileal digestibility and intestinal morphology in broiler chickens. The present work demonstrates the use of double-layered polymers (chitosan, CS and sodium alginate, SA) with opposite charges leading to a dual pH responsiveness. The double-layered microcapsule was studied on physicochemical characteristics, the swelling performance as well as …

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Mass Ratio Variance Majority Cleansing And Minority Oversampling Technique For Class Imbalanced, Piboon Polvimoltham Jan 2022

Mass Ratio Variance Majority Cleansing And Minority Oversampling Technique For Class Imbalanced, Piboon Polvimoltham

Chulalongkorn University Theses and Dissertations (Chula ETD)

A sampling method is one of the basic methods to deal with an imbalance problem appearing in machine learning. A dataset having an imbalance problem has a noticeably skewed distribution among different classes. There are three types of sampling techniques to solve this problem by balancing class distributions, undersampling technique, over-sampling technique, and combined sampling technique. In this research, the mass ratio variance scores of each data point of the same class are computed and used to remove noise from a majority class and synthesise instances from a minority class. The results of this proposed sampling technique improve recall over …

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Comparative Analysis Of Mutational Landscapes Identified From Exome Sequencing Of Tumor Tissues And Circulating Tumor Dna, Julanee Leenanitikul Jan 2022

Comparative Analysis Of Mutational Landscapes Identified From Exome Sequencing Of Tumor Tissues And Circulating Tumor Dna, Julanee Leenanitikul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Next-generation sequencing of circulating tumor DNA (ctDNA) has been used as a noninvasive alternative for cancer diagnosis and characterization of tumor mutational landscape. However, low ctDNA fraction and other factors can limit the ability of ctDNA analysis to capture tumor-specific and actionable variants. In this study, whole-exome sequencings (WES) were performed on paired ctDNA and tumor biopsy in 15 cancer patients to assess the extent of concordance between mutational profiles derived from the two source materials. We found that up to 16.4% ctDNA fraction can still be insufficient for detecting tumor-specific variants and that high concordance with tumor biopsy is …

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Computational Approaches For Identifying Bioactive Compounds Inhibiting Sars-Cov-2 Main Protease, Piyatida Pojtanadithee Jan 2022

Computational Approaches For Identifying Bioactive Compounds Inhibiting Sars-Cov-2 Main Protease, Piyatida Pojtanadithee

Chulalongkorn University Theses and Dissertations (Chula ETD)

The infectious disease caused by the novel coronavirus 2019 has devastatingly affected the global economy and society. However, the drug discovery process from concept to approval requires a significant investment of time and resources. To address these challenges, we employed structure-based virtual screening techniques, including drug-likeness screening, pharmacophore-based virtual screening, molecular docking, molecular dynamics simulation, and fragment molecular orbital calculation. The protein target of this investigation was the main protease or 3-chymotrypsin-like-protease (3CLpro) of the coronavirus, given its pivotal role in the viral replication process. Using our in-house database of natural products and their derivatives, we aimed to identify potent …

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Whole Genome Sequencing, De Novo Assembly, And Comparative Analysis Of Varanus Salvator And Megaustenia Siamensis, Wanna Chetruengchai Jan 2022

Whole Genome Sequencing, De Novo Assembly, And Comparative Analysis Of Varanus Salvator And Megaustenia Siamensis, Wanna Chetruengchai

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: Understanding the animal genome structure and function is pivotal for expanding our current knowledge of evolution, biodiversity, cosmeceutical and medical applications. Each species has a unique characteristic feature. Varanus salvator is a reptile (vertebrate) prevalent in Thailand. It has evolved over millions of years to adapt and survive in urban environments, polluted canals, and garbage dumps. It still survives without noticeable effects. Megaustenia siamensis, an invertebrate, is famous for its ability to produce biological adhesive substances enabling it to stick to trees’ leaves even in heavy rain. However, there is very little genomics or transcriptomics data for V. salvator …

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The Role Of B1 Methylation, Physiologic Replication Independent Endogenous Dna Double Strand Breaks (Phy-Rind-Edsb) And Laminin 511 E8 Proteins In Rat Second Degree Burn Wound Healing, Jiraroch Meevassana Jan 2022

The Role Of B1 Methylation, Physiologic Replication Independent Endogenous Dna Double Strand Breaks (Phy-Rind-Edsb) And Laminin 511 E8 Proteins In Rat Second Degree Burn Wound Healing, Jiraroch Meevassana

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: DNA methylation via short interspersed nuclear element (SINE) small interfering (si)RNA prevents DNA damage and promotes cell proliferation. Furthermore, laminin α5 β1 γ1(LM511) is an extracellular structural protein that can support epithelial cell adhesion and migration. Box A of high-mobility group box 1 protein (Box A of HMGB1) is a common nuclear protein in eukaryotic cells that can reduce DNA damage response toward burn injury. Objective: To investigate whether treatment of burn wounds using B1 siRNA, Box A of HMGB1 and LM511-E8 fragment improved wound closure in a rat second-degree burn wound model. Methods: I performed a cross-sectional analytical …

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Senescent White Blood Cells In Colorectal Carcinoma Patients, Khin Aye Thin Jan 2022

Senescent White Blood Cells In Colorectal Carcinoma Patients, Khin Aye Thin

Chulalongkorn University Theses and Dissertations (Chula ETD)

Colorectal cancer (CRC) and ageing can contribute to changes in immune cells including immuno-senescence. The objectives of the study were to determine if the senescence marker (p16INK4A) was expressed more at higher levels in peripheral white blood cells in CRC compared to age-matched healthy controls. Another aim was to determine the phenotypic changes of T cells, NK cells and monocytes during ageing and CRC in case-control studies. Cases were patients with CRC and controls were matched with cases based on age. Peripheral immune cells were analysed for p16INK4A using immunofluorescence and immunophenotypes were determined with flow cytometry. Correlation studies with …

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The T Cell Senescence In Breast Cancer, Sikrit Denariyakoon Jan 2022

The T Cell Senescence In Breast Cancer, Sikrit Denariyakoon

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: The cancer-immune cell crosstalk is a common immune-evasion mechanism of cancer. This crosstalk can result in epigenetic changes in immune phenotypes to accelerate tumor growth and metastasis. Senescent T lymphocytes are formed during T cell differentiation, and are recently described as one of the dysfunctional T cells in cancer. In breast cancer, estrogen does not only regulate normal physiology in females, but is also involved in cancer development and cancer treatment. It may also attenuate senescent phenotypes, and increase DNA damage in several cell-lines. This thesis therefore examined for the presence of senescent T lymphocytes in breast cancer patients, …

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Screening Of Clostridium Sp. For Butanol Production From Sato (Thai Rice Wine) Factory Wastewater, Julalak Buranaprasopchai Jan 2022

Screening Of Clostridium Sp. For Butanol Production From Sato (Thai Rice Wine) Factory Wastewater, Julalak Buranaprasopchai

Chulalongkorn University Theses and Dissertations (Chula ETD)

The production of Sato, a Thai traditional beverage, yields Sato wastewater (STW), which contains residual rice constituents with high chemical and biological oxygen demands and so forms an environmental problem. In addition, STW often smells rotten from the formation of hydrogen sulfide. To solve this problem, the composition of STW was analyzed for its physiological and chemical characteristics to evaluate its potential as a substrate for ABE fermentation using Clostridium spp., which has never been reported for use in acetone-butanol-ethanol (ABE) fermentation before. Solvent-producing Clostridium isolates were obtained from environmental sources in Thailand, and that producing the highest butanol level …

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Anti-Pathogenic Yeast Malassezia Globosa Activity By Propolis Of Stingless Bee Geniotrigona Thoracica, Kawisara Konsila Jan 2022

Anti-Pathogenic Yeast Malassezia Globosa Activity By Propolis Of Stingless Bee Geniotrigona Thoracica, Kawisara Konsila

Chulalongkorn University Theses and Dissertations (Chula ETD)

Malassezia globosa is a lipophilic pathogen which relates to various chronic skin diseases. Azole drugs are main available treatments, but they have been reported with many side effects and microbial drug resistance. Therefore, the alternative medications should be developed. As the antimicrobial activity of propolis is outstanding, this study aims to investigate the potential of propolis from stingless bee, Geniotrigona thoracica against the pathogenic yeast. The extraction and characterization of the propolis components were done after the obtained extracts were evaluated for anti-M. globosa growth by using agar well diffusion assay and broth microdilution assay. Moreover, Inhibitory Concentration values at …

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Antiproliferative Agents From Mushroom Phellinus Sp., Kulrut Pichayaphinyo Jan 2022

Antiproliferative Agents From Mushroom Phellinus Sp., Kulrut Pichayaphinyo

Chulalongkorn University Theses and Dissertations (Chula ETD)

In this study, Phellinus powdered (600 g) was extracted with methanol and DI water. The methanolic crude extract of the mushroom was partitioned with hexane, dichloromethane, ethyl acetate and methanol respectively. All crude extracts were evaluated antiproliferative activity against lung cancer (A549) and neuroblastoma (SH-SY5Y) cell lines by MTT assay. It was found that the dichloromethane extract (CDE) exhibited the strongest antiproliferative activity with half maximal inhibitory concentration (IC50) values of 132.4 and 106.87 µg/mL against human lung cancer and neuroblastoma cell lines, respectively. The ethyl acetate extract (CEE) exhibited moderate antiproliferative activity with IC50 values of 138.64 and >250 …

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A Comparative Study On Out Of Scope Detection For Chest X-Ray Images, Nuttapol Kamolkunasiri Jan 2022

A Comparative Study On Out Of Scope Detection For Chest X-Ray Images, Nuttapol Kamolkunasiri

Chulalongkorn University Theses and Dissertations (Chula ETD)

Image classification models in actual applications may receive input outside the intended data distribution. For crucial applications such as clinical decision-making, it is critical that a model can recognize and describe such out-of-distribution (OOD) inputs. The objective of this study is to investigate the efficacy of several approaches for OOD identification in medical images. We examine three classes of OOD detection methods (Classification models, Confidence-based models, and Generative models) on the data of X-ray images. We found that simple classification methods and HealthyGAN perform the best overall. However, HealthyGAN cannot generalize to unseen scenarios, while classification models still retain some …

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Effects Of Lipids And Surfactants On The Characteristics Of Asiatic Acid-Loaded Solid Lipid Microparticles, Jatuporn Witarat Jan 2022

Effects Of Lipids And Surfactants On The Characteristics Of Asiatic Acid-Loaded Solid Lipid Microparticles, Jatuporn Witarat

Chulalongkorn University Theses and Dissertations (Chula ETD)

The objective of this study was to evaluate the effects of solid lipids: beeswax and cetyl alcohol, and surfactants: Tween 80®, soybean lecithin and poloxamer 188 on the characteristics of solid lipid microparticles containing asiatic acid (AASLM). The AASLM were prepared from 10% or 15% of beeswax or cetyl alcohol together with 3% of surfactant F1-F12) by melt dispersion cum freeze-drying technique to obtain a solid dosage form. The physicochemical characteristics of the AASLM powders, including appearance, surface morphology, particle size, %labeled amount of asiatic acid (AA) and %entrapment efficiency (EE) were evaluated. The results revealed that AASLM prepared from …

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Factors Associated With And Impacting Coming Out For Sexual Identity Minorities In The United States, Matthew Robert Kusen Jan 2022

Factors Associated With And Impacting Coming Out For Sexual Identity Minorities In The United States, Matthew Robert Kusen

Chulalongkorn University Theses and Dissertations (Chula ETD)

This research aims to explore socio-demographic and other individual factors potentially associated with the probability of coming out as Lesbian, Gay, Bisexual, Queer and other sexual identities (LGBQ+) to friends and family and the probability of being outed as LGBQ+ to family members before being ready or without consent in the United States (UCS). This research analyzed quantitative data from the 2016-17 Generations Study, a nationally representative population-based survey collecting information from LGBQ+ persons residing across the US (N=1,416), and employed both descriptive and multivariate analyses, using the logistic regression model and the Cox proportional hazard model. Several factors were …

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The Socio-Economic Determinants Of The Life Satisfaction Of Older Persons In Myanmar In 2019, Myo Thandar Jan 2022

The Socio-Economic Determinants Of The Life Satisfaction Of Older Persons In Myanmar In 2019, Myo Thandar

Chulalongkorn University Theses and Dissertations (Chula ETD)

Myanmar has undergone significant demographic changes, and the share of the older population has increased. Myanmar is facing the challenge in providing social protections to the increasing number of older people, like many other rapidly-ageing societies. As people get older, their physical health and functional ability deteriorate and, as a result, their life satisfaction also declines in most cases. Therefore, it is crucial to consider factors that contribute to the perception of life satisfaction among this venerable cohort. This study explored the determinants of life satisfaction of older persons and investigated whether there are gender differences in the determinants of …

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Preventive Health Care And Health Care Services Utilization Of Vietnamese Older Persons : Results From National Household Living Standards Survey 2018, Thao Nguyen Thi Jan 2022

Preventive Health Care And Health Care Services Utilization Of Vietnamese Older Persons : Results From National Household Living Standards Survey 2018, Thao Nguyen Thi

Chulalongkorn University Theses and Dissertations (Chula ETD)

As many countries are aging rapidly, improving older persons’ health and reducing the burden of disease are important goals. However, many developing countries still lack effective policies in the areas of preventive health care and health services utilization of older persons. This study aims: (1) to determine the health status by severe injury report and health care service needs of Vietnamese older persons, (2) to investigate the factors associated with the use of health check-up services of Vietnamese older persons, and (3) to investigate the differences in health care services utilization between different medical needs of Vietnamese older persons. Using …

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Learning Model For Improving Quality Of Life Of Cambodian Migrant Workers Working And Living In Thailand, Chanrasmey Lay Jan 2022

Learning Model For Improving Quality Of Life Of Cambodian Migrant Workers Working And Living In Thailand, Chanrasmey Lay

Chulalongkorn University Theses and Dissertations (Chula ETD)

The purpose of this research study were 1) to study the current living situation of Cambodian migrant workers working and living in Thailand, 2) to study how all stakeholders and those Cambodian migrant workers could work together to improve the quality of life of those Cambodian migrant workers living and working in Thailand, and 3) to propose a learning model for improving the quality of life of Cambodian migrant workers working and living in Thailand. The data was collected quantitatively and qualitatively from the survey and in-depth interview. The sample for the survey was 100 Cambodian migrant workers who were …

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Academic Management Strategies Of Secondary Schools In Cambodia Based On The Concept Of Innovation Leadership Skills, Nguon Siek Jan 2022

Academic Management Strategies Of Secondary Schools In Cambodia Based On The Concept Of Innovation Leadership Skills, Nguon Siek

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study aimed to 1) study conceptual frameworks of academic management of secondary schools in Cambodia and innovation leadership skills, 2) study students’ innovation leadership skills levels, 3) analyze strengths, weaknesses, opportunities, and threats of academic management based on the concept of innovation leadership skills, and 4) develop academic management strategies based on the concept of innovation leadership skills. Multiphase mixed-methods design were employed. Samples included 2,662 students as respondents in Phase II and 94 public secondary schools in Phase III. Respondents included school administrators and teachers. Research instruments included evaluation forms and questionnaires. Data were analyzed using frequency, percentage, …

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Classification Of Cardiac Arrhythmias Based On Overlapped Ecg Image With Lightweight Neural Network, Khaing Su Thway Jan 2022

Classification Of Cardiac Arrhythmias Based On Overlapped Ecg Image With Lightweight Neural Network, Khaing Su Thway

Chulalongkorn University Theses and Dissertations (Chula ETD)

This dissertation presents the classification of different types of cardiac arrhythmias, including Atrial Fibrillation (AF), Normal Sinus Rhythm (NSR), Premature Atrial Contraction (PAC), and Premature Ventricular Contraction (PVC), using a lightweight neural network. A novel ECG data transformation method, referred to as transforming into overlapped ECG images, has been developed and utilized as input images for our neural network. During the transformation process, individual heartbeats within a 30-second time frame are cropped based on heart rate calculations. These resulting beats are then overlapped with respect to the x and y axis limits, generating distinctive images representing different arrhythmia types examined …

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Functional Split In 5g Cloud Radio Access Network Using Particle Swarm Optimization, Wai Phyo Jan 2022

Functional Split In 5g Cloud Radio Access Network Using Particle Swarm Optimization, Wai Phyo

Chulalongkorn University Theses and Dissertations (Chula ETD)

The Cloud Radio Access Network (C-RAN) is an innovative approach that has the potential to significantly reduce the expenses of setting up and operating wireless networks. C-RAN's placement of RAN functions, which strives to reduce bandwidth utilization and computation costs, is a critical component. In this study, our main goal is to reduce the costs associated with functionally placing the RAN while accounting for the computational expense and the front-haul bandwidth usage among various users. To achieve this, we propose to apply Particle Swarm Optimization (PSO) to achieve effective allocation of computational resources and the front-haul bandwidth, ensuring an efficient …

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Online Self-Learning System For Prediabetes Patients, Ye Moe Myint Jan 2022

Online Self-Learning System For Prediabetes Patients, Ye Moe Myint

Chulalongkorn University Theses and Dissertations (Chula ETD)

This thesis implements a web-based application that combines a 3D learning center and educational game to facilitate the monitoring, management, and treatment of patients with prediabetes mellitus, by providing exercise plans and controlled diets. The application utilizes advanced web technologies, 3D modeling, and gamification principles to create an engaging learning experience. User-centered design ensures usability, and testing demonstrates positive outcomes, including increased knowledge, motivation, and engagement. This research contributes to digital health interventions by empowering prediabetes patients with informed decision-making and healthy habits. Future directions include expanding the application, refining the user interface, and evaluating long-term impact on prediabetes management.

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Effects Of The Writing Instructional Model With Integration Of Inquiry-Based Learning And Visual Literacy On 21st Century Skills Of Efl Learners, Patsawut Sukserm Jan 2022

Effects Of The Writing Instructional Model With Integration Of Inquiry-Based Learning And Visual Literacy On 21st Century Skills Of Efl Learners, Patsawut Sukserm

Chulalongkorn University Theses and Dissertations (Chula ETD)

Although a body of research illustrates the potential of inquiry-based learning in promoting the 21st century skills among English as a Foreign Language (EFL) students (AbuRezeq, 2018; Imansyan et al., 2019; Milatasari, 2013; Palupi et al., 2020; Tongjean et al., 2019), other studies have indicated its occasional failure in eliciting students’ engagement (Duschl & Wright, 1989; Gill, 2005), which affects students’ success in language learning. This results in the need to leverage other pedagogical strategies, including visual literacy, to increase the efficacy of inquiry-based learning (Gonzalez-Ledo, 2015; Maricimoi, 2017; Navidinia et al., 2018; Rokhaniyah, 2019, Sulastri, 2019; Tayib, 2015; Villasor, …

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Knowledge, Attitude And Practices On Potato Pest Management Of Ethnic Farmers In Southern Shan State, Myanmar, Pyae Pa Pa Aung Jan 2022

Knowledge, Attitude And Practices On Potato Pest Management Of Ethnic Farmers In Southern Shan State, Myanmar, Pyae Pa Pa Aung

Chulalongkorn University Theses and Dissertations (Chula ETD)

Potato is cultivated as the main tuber crop which is essential for ethnic farmers’ household income in Southern Shan State, Myanmar. Most ethnic farmers use chemical pesticides widely to enhance crop yield and to control pests in the farm. The use of chemical pesticides could lead to a series of health impacts of the farmers and environmental issues. The main aim of the study is to explore farmers’ knowledge, attitude and current farm practices on pest management in potato production. The participants of 100 farmers were chosen from each village with a cluster and purposive sampling technique using structured questionnaires …

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Comparison Of Volumetric Changes At Implant Connector Among Three Different Types Of Abutment After Cyclic Loading, Piyawan Jirayusakamol Jan 2022

Comparison Of Volumetric Changes At Implant Connector Among Three Different Types Of Abutment After Cyclic Loading, Piyawan Jirayusakamol

Chulalongkorn University Theses and Dissertations (Chula ETD)

The aim of this study was to compare the volumetric change of dental implant among three different types of abutments after cyclic loading.Thirty dental implants (4.1x10 mm., Straumann®) were used .All of them were inserted in acrylic resin block with usual surgical protocol to gain primary stability and be able to retrieve for volumetric measurement later. Ten of each dental implant connected with Titanium abutment (Group1: Variobase abutment Straumann®), Gold abutment (Group2: UCLA abutment Straumann®) and Zirconia abutment (Group 3: Care abutment Straumann®) consecutively. Then all specimen was submitted to cyclic loading (1x106 cycles, axial load, 100N, 15 Hz) at …

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Association Among Anterior Maxillary Dental Arch Form, Alveolar Bone Thickness And Sagittal Root Position Of Maxillary Central Incisor : A Cone Beam Computed Tomography Analysis, Suttikiat Somvasoontra Jan 2022

Association Among Anterior Maxillary Dental Arch Form, Alveolar Bone Thickness And Sagittal Root Position Of Maxillary Central Incisor : A Cone Beam Computed Tomography Analysis, Suttikiat Somvasoontra

Chulalongkorn University Theses and Dissertations (Chula ETD)

Purpose: This study evaluated the association among the dental arch form, age-sex groups, and sagittal root position regarding alveolar bone thickness in the maxillary central incisor using cone-beam computed tomography (CBCT) images. Materials and Methods: CBCT images of 280 patients were categorized based on the dental arch form and age-sex groups. Five hundred and sixty sagittal CBCT images of the maxillary central incisors were examined to measure the labial and palatal bone thickness at the root apex level, at the mid-root level and 3 mm apically from cemento-enamel junction, with SRP classification. Chi-square, Kruskal-Wallis test, and multiple linear regression were …

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The Analysis Of Enhanced Momentum Strategies In The Stock Exchange Of Thailand, Chayakon Kamolsawat Jan 2022

The Analysis Of Enhanced Momentum Strategies In The Stock Exchange Of Thailand, Chayakon Kamolsawat

Chulalongkorn University Theses and Dissertations (Chula ETD)

The purpose of this study is to investigate the effectiveness of momentum strategies in investment portfolios, a well-known anomaly in the efficient market hypothesis, by portfolio are constructed by long winners and short losers. Specifically, the study focuses on the use of volatility to enhance momentum strategies in the Stock Exchange of Thailand from January 2013 to December 2022. The enhanced momentum strategies under investigation vary the portfolio weight with volatility and can be classified into constant volatility-scaled, constant semi-volatility-scaled, and dynamic-scaled approaches. The research aims to achieve two main objectives. Firstly, to analyze the potential of the enhanced momentum …

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The Impact Of Government Response To Covid-19 On Stock Return Predictability, Disayadej Dangdej Jan 2022

The Impact Of Government Response To Covid-19 On Stock Return Predictability, Disayadej Dangdej

Chulalongkorn University Theses and Dissertations (Chula ETD)

Recession is known to cause an increase in stock return predictability. The COVID-19 pandemics had not only resulted in sickness and loss of life but also plunged global economy into recession prompting governments to come up with measures to combat the disease. This paper first confirms that return predictability increased due the spread of COVID-19 using data from 41 countries on variations of popular predictors. Furthermore, it shows that government responses to COVID-19 alleviated the pandemic, the recession and reduced the return predictability with varying impact for different government measures. However, cases and deaths from COVID-19 which should have intensified …

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Development Of High Protein Beverage From Hydrolyzed Egg White, Nuntorn Charoensak Jan 2022

Development Of High Protein Beverage From Hydrolyzed Egg White, Nuntorn Charoensak

Chulalongkorn University Theses and Dissertations (Chula ETD)

The primary objective of this study was to examine the impact of enzymatic treatment on pasteurized egg white protein (EWP) and assess its influence on various physicochemical properties and antioxidant activity. Our findings revealed that the addition of SDAY10 enzymes led to a significant increase in lightness (L*), redness (a*), and yellowness (b*) parameters. Furthermore, higher concentrations of the enzyme resulted in a considerable reduction in pH, viscosity, and volume mean diameter (D4,3) of EWP protein compared to the control group (P < 0.05). Additionally, the application of SDAY10 enzyme (0.1-0.3% w/v) for EWP hydrolysis exhibited a noteworthy enhancement in antioxidant activity (measured by DPPH, ABTS, and FRAP assays) compared to lower enzyme concentrations. Notably, the 0.3% concentration of SDAY10 exhibited the highest release of amino acids during in vitro digestion and received the highest sensory evaluation score. Consequently, employing SDAY10 enzymes at a concentration of 0.3% w/v for EWP hydrolysis demonstrates significant potential for improving the physical properties of EWP and enhancing antioxidant activity. However, it is imperative to investigate the sensory evaluation with regards to the bitterness of the product developed using such enzymes.

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