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2022

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The Experiences And Transition Of Black Former Student Athletes Through And Out Of College, Nyjah Lane Jan 2022

The Experiences And Transition Of Black Former Student Athletes Through And Out Of College, Nyjah Lane

Masters Theses

Using a narrative approach this researcher used a qualitative study to examine the experiences and transitions of former Black student athletes at a Division I institution. The study involved four participants who were three to four years removed from completing college and athletic retirement. Schlossberg’s (1981) transition theory, Astin’s (1999) involvement theory, and Baxter Magolda’s (2008) Self authorship theory was used as the theoretical frameworks for this study. The findings provide insight in to how their experiences as college student athletes impacted their ability to graduate and transition out of college. The participants relied on the support and strategies they …


Identification And Cloning Of Transcripts From Triterpenoid-Induced Neuronal Outgrowth In Neuro-2a Cells From Mus Musculus, Meshael Alrashidi Jan 2022

Identification And Cloning Of Transcripts From Triterpenoid-Induced Neuronal Outgrowth In Neuro-2a Cells From Mus Musculus, Meshael Alrashidi

Masters Theses

Neurodegenerative diseases severely reduce quality of life and are often responsible for the death of those suffering from them. In addition to the societal toll these diseases inflict on populations, the health care costs are estimated to be hundreds of billions of dollars annually for the U.S. alone. Unfortunately, direct pharmacological treatment for some of the most common of these diseases, such as Alzheimer’s, remains elusive. Traditional medicine in China and India have recommended a variety of plants for preventing and treating these diseases. For example, Centella asiatica (L.) Urban, also knows as Gotu Kola, is believed to treat and …


Structural Basis Of Bacterial Flagellin For Naip5 Binding And Nlrc4 Inflammasome Activation And The Mechanism Of Flagellin Induced Release Of Cytokines In Vivo, Jian Cui Jan 2022

Structural Basis Of Bacterial Flagellin For Naip5 Binding And Nlrc4 Inflammasome Activation And The Mechanism Of Flagellin Induced Release Of Cytokines In Vivo, Jian Cui

Theses and Dissertations--Chemistry

The bacterial flagellum is a whip-like structure that protrudes from the cell membrane and is one of the most complex and dynamic biological molecular machines that propels bacteria to swim toward beneficial environments and the sites of infection. It is composed of a basal body, a hook, and a long filament. The flagellar filament contains thousands of copies of the protein flagellin (FliC) monomer arranged helically and ending with a filament cap composed of oligomer protein FliD. The overall structure of the filament core is preserved across bacterial species, while the outer domains exhibit high variability, and in some cases …


Mechanism Of Antibiotic Permeability Through The Gram-Negative Bacterial Envelope, Olaniyi Alegun Jan 2022

Mechanism Of Antibiotic Permeability Through The Gram-Negative Bacterial Envelope, Olaniyi Alegun

Theses and Dissertations--Chemistry

The outer membrane of Gram-negative bacteria (GN) makes them distinct among superbugs that are associated with the development of antibiotic resistance. The outer membrane, and inner membrane, separated by the periplasm, form a double-membrane barrier to the entry of antibiotics into the cell. Several studies have been conducted to examine the role of outer membrane modifications such as porins, lipopolysaccharides, and efflux pumps on antibiotic resistance. However, there is a paucity of knowledge on how antibiotics behave in the periplasm, to gain access into their target region. My thesis focuses on understanding the mechanism of antibiotic permeability through the cellular …


Antibiotic Permeation In Gram-Negative Bacteria And Contribution Of Inflammasome Activation And Pyroptosis In Pathogenesis Of Salmonella Systemic Infection, Ankit Pandeya Jan 2022

Antibiotic Permeation In Gram-Negative Bacteria And Contribution Of Inflammasome Activation And Pyroptosis In Pathogenesis Of Salmonella Systemic Infection, Ankit Pandeya

Theses and Dissertations--Chemistry

Antibiotic resistance is one of the major global issues in the field of public health and medicine. Good antibiotic candidates need to be selectively toxic, inhibit cellular target, and effectively penetrate and accumulate in bacterial cells. The last factor is a formidable barrier in the development of antimicrobials effective in Gram-negative bacteria, due to the presence of two layers of cell envelope. The first half of my thesis focuses on understanding the permeation of small molecules through this formidable cell envelope, distribution inside the cell of Gram-negative bacteria, and design of novel methods to make small molecules effectively cross the …


Nicotine And Cotinine: Microbial Modulators Of The Immune Response, Jourdan Lakes Jan 2022

Nicotine And Cotinine: Microbial Modulators Of The Immune Response, Jourdan Lakes

Theses and Dissertations--Chemistry

The consumption of tobacco products is a known contributor to a variety of health conditions and disease pathologies including cardiovascular and lung diseases. In addition to these well-known pathological effects of tobacco use, it has been established recently that tobacco consumption as well as nicotine consumption alone results in distinct, dysbiotic perturbations to the enteric microflora of the gastrointestinal tract. Previous research into the intestinal microbiome has demonstrated that these microbes are active contributors to the maintenance of a homeostatic and tolerogenic environment within the host. In fact, the presence of our enteric microflora is necessary for the proper development …


Severe Crohn’S Disease With Intra-Abdominal Fistula: First Reported Case From Tanzania, Nadeem Kassam, Omar Aziz, Eric Aghan, Melchisedeck Mandwa, Caroline Ngimba, Hanifa Mbithe, Salim Surani, Casmir Wambura Jan 2022

Severe Crohn’S Disease With Intra-Abdominal Fistula: First Reported Case From Tanzania, Nadeem Kassam, Omar Aziz, Eric Aghan, Melchisedeck Mandwa, Caroline Ngimba, Hanifa Mbithe, Salim Surani, Casmir Wambura

Internal Medicine, East Africa

We describe a case of Crohn's disease occurring in a young Tanzanian female. Crohn’s disease is rare in Africa and not encountered normally. The presentation of Crohn’s disease overlaps with many other abdominal disorders that are common in an African setting, such as tuberculosis and schistosomiasis. The disease is probably underdiagnosed in Africa due to limitations in diagnostic testing and rarity.


Sherman's Shakes: A Story About Living With Epilepsy, Garrett Sacco Jan 2022

Sherman's Shakes: A Story About Living With Epilepsy, Garrett Sacco

The Art of Medicine

No abstract provided.


Untitled, Sophie Cemaj Jan 2022

Untitled, Sophie Cemaj

The Art of Medicine

No abstract provided.


The Unfortunate Case Of Dr. Silvan, Tom Schroeder Jan 2022

The Unfortunate Case Of Dr. Silvan, Tom Schroeder

The Art of Medicine

No abstract provided.


Medicine's No Longer Healing, Natasha Hongsermeier-Graves Jan 2022

Medicine's No Longer Healing, Natasha Hongsermeier-Graves

The Art of Medicine

No abstract provided.


Self Portrait, Tiffany Truong Jan 2022

Self Portrait, Tiffany Truong

The Art of Medicine

No abstract provided.


1000 Cuts ; Difficult, Stephanie Hartman Jan 2022

1000 Cuts ; Difficult, Stephanie Hartman

The Art of Medicine

No abstract provided.


Ethics Consults, Rebecca Anderson Jan 2022

Ethics Consults, Rebecca Anderson

The Art of Medicine

No abstract provided.


Good Morning Covid Nation, Gillian Rolfe Jan 2022

Good Morning Covid Nation, Gillian Rolfe

The Art of Medicine

No abstract provided.


Untitled, Keely Reidlberger Jan 2022

Untitled, Keely Reidlberger

The Art of Medicine

No abstract provided.


Ephemeral, Alicia Phillips Jan 2022

Ephemeral, Alicia Phillips

The Art of Medicine

No abstract provided.


We'll Get Through This, Ben Mcintire Jan 2022

We'll Get Through This, Ben Mcintire

The Art of Medicine

No abstract provided.


Art Of Medicine - 2022 Jan 2022

Art Of Medicine - 2022

The Art of Medicine

No abstract provided.


Promoting Personal And Social Responsibility In Higher Education, Karisa L. Kuipers Jan 2022

Promoting Personal And Social Responsibility In Higher Education, Karisa L. Kuipers

Graduate Research Theses & Dissertations

This dissertation utilizes a three-paper approach to explore the topic of promoting personal and social responsibility (PSR) in higher education. Paper one is a conceptual piece that examines the alignment between the Teaching Personal and Social Responsibility (TPSR) model and PSR in higher education. The paper proposed a kinesiology-based framework (i.e., the TPSR model) to assist in defining, implementing, and evaluating PSR education with post-secondary students. The paper offered a general overview of the higher education landscape and then presented its alignment with the TPSR model. Recommendations for implementing the framework into higher education were shared, and challenges with integrating …


Heathen Husband: The Corrupting Patriarchal Hierarchy In Shakespeare’S Othello And Its Absence In Cinthio’S Gli Hecatommithi, Heavyn Renee Lester Jan 2022

Heathen Husband: The Corrupting Patriarchal Hierarchy In Shakespeare’S Othello And Its Absence In Cinthio’S Gli Hecatommithi, Heavyn Renee Lester

Graduate Research Theses & Dissertations

This thesis places William Shakespeare’s Othello within cultural context to examine the moral corruption that Desdemona and Othello undergo once they fulfill marital roles within a patriarchal hierarchy that reflects the hierarchy religious conduct literature calls on Christians to maintain within marriage. At the same time, this thesis contrasts Shakespeare’s Othello with the Italian story of Disdemona and a Moorish captain within Decade Three of Cinthio’s Gli Hecatommithi. Hecatommithi does not ascribe a corrupting power to patriarchal hierarchy or explore Othello’s downfall in relation to his Christian faith. This thesis determines that the alterations Shakespeare makes to Othello’s source material …


Social Support Networks As Buffers Against The Association Between Covid-19 Related Stress And Depression: A Latent Profile, Three-Way Interaction Approach, Kathleen Kelly Jan 2022

Social Support Networks As Buffers Against The Association Between Covid-19 Related Stress And Depression: A Latent Profile, Three-Way Interaction Approach, Kathleen Kelly

Graduate Research Theses & Dissertations

BACKGROUND: Since the beginning of the pandemic, approximately one in four people in the general public have experienced moderate to severe levels of stress, which precures the development of depression. Young adults were extremely vulnerable to COVID-19 related stressors developing into mental health disorders (Wang et al., 2020). PURPOSE: The study aimed to explore this vulnerability in a young adult, undergraduate sample. The main purpose was to explore to what extent profiles of sources of social support networks can strengthen or weaken the proposed association between various types of COVID- 19-related stress and depression and whether social support was a …


Parent Training Workshop For Children With Selective Mutism: A Randomized-Controlled Trial, Jacqueline M. Pabis Jan 2022

Parent Training Workshop For Children With Selective Mutism: A Randomized-Controlled Trial, Jacqueline M. Pabis

Graduate Research Theses & Dissertations

The present study aimed to examine the efficacy of a parent-based workshop for child anxiety adapted from a novel parent-based intervention, Supportive Parenting for Anxious Childhood Emotions (SPACE). This study expanded upon the current literature as the intervention was conducted with a sample consisting of parents with children who have selective mutism (SM). The sample included 53 parents (Mage = 40.34 years, 98% female, 77.4% White) of children who have SM symptoms. Participants were randomly assigned to the parent workshop condition (n = 26) or the waitlist control condition (n = 27). Participants in the workshop condition completed a 6-week …


Biomechanical Evaluation Of Hand Representation For Typing In Virtual Reality, Mobasshira Zaman Jan 2022

Biomechanical Evaluation Of Hand Representation For Typing In Virtual Reality, Mobasshira Zaman

Graduate Research Theses & Dissertations

Virtual reality (VR) is becoming popular in the workplace recently. Text entry is thus now important for efficient office use and occupational use of VR, and VR paired with a conventional keyboard is suitable for long text entry. There has been a lack of research on physical demand, posture, motion, and cognitive demand, along with the performance of typing on VR. Presence of virtual hands while typing in VR may affect typing performance, physical demand, and posture. The focus of this study was to evaluate the biomechanical effect of hand representation for typing on VR using a conventional keyboard. Fifteen …


The Effect Of Fatigue On Lower Extremity Electromyography During Clean Performance In Elite Female Weightlifters, John A. Littner Jan 2022

The Effect Of Fatigue On Lower Extremity Electromyography During Clean Performance In Elite Female Weightlifters, John A. Littner

Graduate Research Theses & Dissertations

The clean is a primary movement in the sport of Olympic weightlifting. Management of fatigue is essential to optimizing weightlifting performance. The purpose of this study was to examine the effects of fatigue on EMG activation during clean performance in elite female weightlifters. Electromyography (EMG) data was collected bilaterally from the vastus lateralis (VM) and vastus lateralis (VL) during maximum voluntary isometric contraction (MVIC) and clean trials. Muscle activity was collected during pre- and post-fatigue clean trials at 60%, 70%, and 80% of the subject’s self-reported one repetition maximum (1RM). Subjects completed a fatiguing protocol consisting of two sets of …


Disincanto, Daniel Barotti Jan 2022

Disincanto, Daniel Barotti

Mighty Pen Project Anthology & Archive

After joining the navy, a young sailor finds on his first posting that the stories he's been told aren't as true as he'd like them to be.

Articles, stories, and other compositions in this archive were written by participants in the Mighty Pen Project. The program, developed by author David L. Robbins, and in partnership with Virginia Commonwealth University and the Virginia War Memorial in Richmond, Virginia, offers veterans and their family members a customized twelve-week writing class, free of charge. The program encourages, supports, and assists participants in sharing their stories and experiences of military experience so both writer …


Fundamental Study Of Dopant Effect And Toxicity In Perovskite Materials, Xun Li Jan 2022

Fundamental Study Of Dopant Effect And Toxicity In Perovskite Materials, Xun Li

Graduate Research Theses & Dissertations

This dissertation comprehensively studies the research on organic-inorganic hybrid perovskite to solve the toxicity issue of perovskite-based solar cells under practical conditions, understand the doping effect on hybrid perovskite materials in optoelectronic applications, and improve the photovoltaic performance of perovskite-based solar cells by composition tailoring. Specifically, an innovative and simple chemical approach was invented for on-device sequestration of toxic Pb leakage caused by severe device damage. To mimic the practical conditions, the sequestration of lead leakage was conducted under cold water, warm water, acid water, dripping water, and water with competitive ions. Crucially, it was found that at least 96% …


Exploring The Morphometrics Of The Diatom Fragilariopsis Kerguelensis As A Proxy For Paleo-Sea Surface Temperature In The Late Pleistocene-Holocene Southern Ocean, Joseph Anthony Ruggiero Jan 2022

Exploring The Morphometrics Of The Diatom Fragilariopsis Kerguelensis As A Proxy For Paleo-Sea Surface Temperature In The Late Pleistocene-Holocene Southern Ocean, Joseph Anthony Ruggiero

Graduate Research Theses & Dissertations

The Southern Ocean has played a large role in moderating global climate since its inception in the Oligocene. With the onset of anthropogenic global warming, it is now more necessary than ever that we understand the world’s climate during periods of rapidly fluctuating temperature in the past. Climatic forecasts are informed by paleoenvironmental conditions of the past during these turbulent periods, which we can examine using proxy data. This thesis assesses a potential proxy for Sea Surface Temperature (SST) through morphometric analysis of the Southern Ocean diatom Fragilariopsis kerguelensis in the Amundsen Sea, West Antarctica. This proxy is based off …


Eat Glass And Walk On Fire, While Managing A Pandemic: A Narrative Study Of African American Women Who Serve As Chief Housing Officers, Valronica Marie Scales Jan 2022

Eat Glass And Walk On Fire, While Managing A Pandemic: A Narrative Study Of African American Women Who Serve As Chief Housing Officers, Valronica Marie Scales

Graduate Research Theses & Dissertations

Creating uncertainty and stress, the COVID-19 pandemic and increased attention on racial relations, drastically changed how higher education and student affairs operated. For African American women, combatting racism and sexism has always been a daily occurrence in their professional and personal life but the pandemic heightened the challenges African American women had to overcome. This narrative inquiry study explored the lived experiences of African American women who were serving as Chief Housing Officers at Predominately White Institutions during the first 18-months of the COVID-19 pandemic. Findings highlight how the intersection of sexism and racism shaped the lived experiences of the …


“There Was Me Before Prp, And Then There Was Me After I Participated In Prp”: A Mixed-Methods Program Evaluation Of A Pharmacy Summer Pipeline Program, Cynthia Schaefer Jan 2022

“There Was Me Before Prp, And Then There Was Me After I Participated In Prp”: A Mixed-Methods Program Evaluation Of A Pharmacy Summer Pipeline Program, Cynthia Schaefer

Graduate Research Theses & Dissertations

Nationwide, there has been a decline in the number of applicants to PharmD programs.

Additionally, there is a lack of diversity in the healthcare workforce that leads to inequitable healthcare for diverse populations of patients. As a result, various recruitment tactics, including pipeline programs, have been used to develop a larger, more diverse applicant pool to the College of Pharmacy at a regional satellite campus in the Midwest. The purpose of this mixed methods summative program evaluation was to examine the experiences of participants of a pipeline program hosted at a regional satellite campus for a pharmacy program to determine …