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2022

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Training Needs And Applications For Special Educators With Paraeducator Supervision Responsibilities, Joanna M. Cornejo Dec 2022

Training Needs And Applications For Special Educators With Paraeducator Supervision Responsibilities, Joanna M. Cornejo

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

This project highlights the need for training for paraeducators working in Special Education settings. Duties performed by paraeducators often overlap with teacher duties and much of the direct instruction provided to students in self-contained classrooms is delivered by paraeducators. The tasks of training and supervising paraeducators often falls on the special education teacher, who may not have received training in supervision. The project includes a brief review of the literature on this topic and two project reports. I designed my project with the objective of improving the quality of instruction being delivered to students in my classroom through training of …


Mountain States Oilseeds: Risk Management For Safflower Production In The Intermountain West, Jameson F. Packer Dec 2022

Mountain States Oilseeds: Risk Management For Safflower Production In The Intermountain West, Jameson F. Packer

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Safflower is an oilseed crop primarily produced in the western Great Plains because of its compatibility with cereal grain equipment. Varieties grown in that region are harvested predominantly for seeds high in safflower oil and oleic acid that are processed and used in cooking oil, human nutrition, and other health and beauty products. Safflower is also grown in Utah, Idaho, and California for birdseed mixes due to the region’s arid climate, which yields a crisp, white seed that is highly favorable in the birdseed market. Mountain States Oilseeds, headquartered in American Falls, Idaho, is one of the United States’ largest …


Computer-Aided Drug Discovery For Helicobacter Pylori, Nicole Ann Vita Dec 2022

Computer-Aided Drug Discovery For Helicobacter Pylori, Nicole Ann Vita

Theses and Dissertations (ETD)

Helicobacter pylori is a high-priority drug-resistant pathogen and is currently the only bacteria considered to be a class I carcinogen and there is a critical need to identify novel chemical matter to treat H. pylori infections. Hp is responsible for greater than 60% of gastric cancer related deaths and 89% of all gastric cancer morbidities. In a previous study, our lab identified novel Hp thienopyrmidine inhibitors that target respiratory complex I, an essential enzyme in respiration. Respiratory complex I is a large asymmetric multidomain and membrane bound enzyme and due to these innate features, it is not practical for biophysical …


Faith-Based Counseling Versus Traditional Psychotherapy: A Phenomenological Evaluation Of African American Protestant Experiences, Shannon Gray Dec 2022

Faith-Based Counseling Versus Traditional Psychotherapy: A Phenomenological Evaluation Of African American Protestant Experiences, Shannon Gray

Dissertations

This phenomenological study was designed to evaluate the experiences of African American Christian adult clients within traditional psychotherapy and faith-based counseling settings. Research has shown various therapist/counselor identities affect Christian African American clients, and that Christians as well as African Americans have historically been less likely to pursue traditional psychotherapy for a variety of reasons. Participants were six African American Christian adult participants (three traditional psychotherapy participants and three faith-based counseling participants). All participants were asked open-ended questions about their experiences in traditional psychotherapy or faith-based counseling. In addition, they were asked to evaluate several aspects of their therapy/counseling experience …


Building On The Lasting Benefits Of Attending A Voluntary Prekindergarten Program, Ashley Swickle Dec 2022

Building On The Lasting Benefits Of Attending A Voluntary Prekindergarten Program, Ashley Swickle

Dissertations

The expectations of kindergarten students have drastically changed over the years. Kindergarten students who have not attended a voluntary pre-kindergarten (VPK) program may be at a disadvantage in behavior and academics. The purpose of this study is to show the benefits of a VPK program. My study includes kindergarten students at the school under study whose progress monitoring scores in the beginning of the year are compared to student’s scores who have never attended a VPK program, the amount of behavior referrals is also compared. The anticipated results are that kindergarten students who attended VPK will out-perform their peers who …


Prenatal Opioid Use And Neonatal Abstinence Syndrome: A Review Of The Neurophysiological, Neuropsychological, And Behavioral/Emotional/Social Impacts In The Pediatric Population, Candice Gore Dec 2022

Prenatal Opioid Use And Neonatal Abstinence Syndrome: A Review Of The Neurophysiological, Neuropsychological, And Behavioral/Emotional/Social Impacts In The Pediatric Population, Candice Gore

Dissertations

The opioid epidemic over the past two decades has raised concerns regarding the developmental fetal impact of prenatal opioid use. Research in this area continues to grow, but largely has focused on treatment for neonates experiencing withdrawal symptoms postnatally. Long term clinical implications for this at-risk population have not been studied extensively leaving many gaps in research and highlighting the need for future empirical studies. This literature review will examine the neurophysiological, neuropsychological, and the behavioral/social/emotional impacts on infants, toddlers, and school aged children who were prenatally exposed to opioids with or without the diagnosis of neonatal abstinence syndrome. Providing …


Lifestyle Choices Related To Food Consumption And Their Relationship To Depression, Steven L. Jennings Jr. Dec 2022

Lifestyle Choices Related To Food Consumption And Their Relationship To Depression, Steven L. Jennings Jr.

Dissertations

Dieting, or the act of restricting oneself to small amounts or particular kinds of foods on the basis of health, spirituality, lifestyle, and moral decisions, is a practice that dates to 1066 A.D. However, with social media being as influential as it is, one might believe dieting is a new obsession or at least an obsession to which popular culture is returning. Despite this, it is only in recent years that researchers have begun to focus on the health benefits of such behaviors. The present study was designed to take this focus a step further by exploring the potential risks …


Identifying Motivations Of New Counselors For Continuing Professional Development Of Multicultural Competencies: A Qualitative Study, Larry English Dec 2022

Identifying Motivations Of New Counselors For Continuing Professional Development Of Multicultural Competencies: A Qualitative Study, Larry English

Dissertations

The need to increase multicultural counseling skills is a crucial area of focus in the continued evolution of the counseling profession. This necessity is due to a number of factors, including the ongoing demographic and societal changes in the United States. The research has helped to bring awareness of the need for increased and continued professional development in the area of cultural literacy and multicultural competencies skills for beginning counselors and others in counseling-related programs. At the micro level, the research investigated new clinicians’ self-awareness of their own biases, assumptions, internalized/externalized actions, and beliefs toward other cultures. The purpose of …


Us Scientific Leadership Addressing Energy, Ecosystems, Climate, And Sustainable Prosperity: Report In Brief From The Berac Subcommittee On International Benchmarking, Maureen Mccann, Patrick Reed, Ana Alonso, Ludmilla Aristilde, Massie S. Ballon, Crysten Blaby, Allison A. Campbell, Kenneth James Davis, Brian H. Davison, Ben Evans, Robert F. Fischetti, Serita D. Frey, Ann M. Fridlind, Efi Foufoula-Georgiou, Ramon Gonzalez, Michael N. Gooseff, Nathan Hillson, Janet Jansson, Klaus Keller, Markus Kleber, Costas Maranas, Gerald A. Meehl, Himadri Pakrasi, Jennifer Pett-Ridge, Kristala Prather, Johannes Quaas, G. Philip Robertson, Alistair Rogers, Tim Scheibe, Thomas R. Schneider, Gary Stacey, Margaret S. Torn, Kerstin Kleese Van Dam, Detlef Vuuren, John Weyant, Stan Wullschleger, Shaocheng Xie, Seung Yon (Sue) Rhee, Huimin Zhao Dec 2022

Us Scientific Leadership Addressing Energy, Ecosystems, Climate, And Sustainable Prosperity: Report In Brief From The Berac Subcommittee On International Benchmarking, Maureen Mccann, Patrick Reed, Ana Alonso, Ludmilla Aristilde, Massie S. Ballon, Crysten Blaby, Allison A. Campbell, Kenneth James Davis, Brian H. Davison, Ben Evans, Robert F. Fischetti, Serita D. Frey, Ann M. Fridlind, Efi Foufoula-Georgiou, Ramon Gonzalez, Michael N. Gooseff, Nathan Hillson, Janet Jansson, Klaus Keller, Markus Kleber, Costas Maranas, Gerald A. Meehl, Himadri Pakrasi, Jennifer Pett-Ridge, Kristala Prather, Johannes Quaas, G. Philip Robertson, Alistair Rogers, Tim Scheibe, Thomas R. Schneider, Gary Stacey, Margaret S. Torn, Kerstin Kleese Van Dam, Detlef Vuuren, John Weyant, Stan Wullschleger, Shaocheng Xie, Seung Yon (Sue) Rhee, Huimin Zhao

Faculty Publications

This document presents the subcommittee’s overarching and domain-specific findings and recommendations for the next decade, identified by consensus across the full BERAC subcommittee and experts interviewed for this assessment.


Call The Doctor! A Study Of Parental Medical Nonadherence Within Child Custody Proceedings, Karissa Lynn Cummons Dec 2022

Call The Doctor! A Study Of Parental Medical Nonadherence Within Child Custody Proceedings, Karissa Lynn Cummons

Theses and Dissertations

Medical nonadherence is a common and formidable problem that many pediatric healthcare providers face when treating children with acute and chronic medical conditions because adhering to a physicians’ treatment recommendations is beneficial for successful treatment, disease prevention, and healthy promotion (Dawood et al., 2010). It was estimated that at least one third of patients are unable to complete or adhere to relatively short treatment regimens (Dawood et al., 2010). Reasons for nonadherence to a physicians’ recommendations range from extended duration of treatment, multiple prescribed medications, and periods of symptom remission (Dawood et al., 2010). Despite a parent’s or family’s reason …


Intersections Of Gender And Age: Identification And Attributional Processes On Leadership Effectiveness, Kayla Lynne Bigerton Dec 2022

Intersections Of Gender And Age: Identification And Attributional Processes On Leadership Effectiveness, Kayla Lynne Bigerton

Theses and Dissertations

As more women enter leadership roles and the ages of leaders becomes more diverse, there is a need for more intersectional research. An intersectional approach was used to assess the impact of leader gender and age on leadership effectiveness through identification and attributional processes. In doing so, different age conceptualizations were also examined. Gender did not have an impact on identification and attributional processes and age had mixed results. Age similarity was not significantly related to leader identification, but perceived leader age had a negative relationship with idiosyncratic fit. Further, social age was examined with different age ranges representing "young”, …


The Effect Of Video Model Dosage And Self-Monitoring On Parent's Use Of Language-Promoting Behavior, Kacie Marie Mcgarry Dec 2022

The Effect Of Video Model Dosage And Self-Monitoring On Parent's Use Of Language-Promoting Behavior, Kacie Marie Mcgarry

Theses and Dissertations

Previous research has found a disparity between the language trajectories of children within a high, medium, or low-economic-status family. A relationship is reliably found between the language trajectory of toddlers and success throughout school. This study will evaluate a training package to teach parents to engage in behaviors that promote language and assess the training's short-term effect on the trajectories of children (i.e., growing language) within low-socioeconomic backgrounds. Specifically, experimenters will evaluate the impact of the dosage of video modeling, self-evaluation, and self-monitoring on the acquisition of the targeted skills. Data may suggest that the more accurate the individual is …


Modeling Settlement And Filtration Of The Indian River Lagoon Benthic Community, With An Emphasis On Living Dock Restoration Mats, Sandra Lisette Rech Dec 2022

Modeling Settlement And Filtration Of The Indian River Lagoon Benthic Community, With An Emphasis On Living Dock Restoration Mats, Sandra Lisette Rech

Theses and Dissertations

The Indian River Lagoon (IRL) is one of the most biologically diverse estuaries in North America. An increase in population and anthropogenic effects have led to eutrophication, a decline in water quality, and overall degradation. The Living Docks program is a citizen science initiative started at the Florida Institute of Technology for lagoon restoration. In this program, public and private docks are volunteered to become Living Docks, where oyster mats made of plastic mesh and dead, dried oyster shells are attached to dock pilings in an effort to provide a natural substrate for benthic organism growth. The community which develops …


The Relationship Between Hallucinations And Visuospatial Impairment Among Individuals With Dementia, Ruta Sohoni Dec 2022

The Relationship Between Hallucinations And Visuospatial Impairment Among Individuals With Dementia, Ruta Sohoni

Theses and Dissertations

Objective: This study examines the neuropsychological functioning, specifically using the Hooper Visual Organization Test (VOT), to understand the impact of hallucinations on the level of impairment in the visuospatial domain.

Method: Archival data obtained over three years from a total of 73 patients from the Health First Memory Disorder Clinic was used in this study. Participants were included in the study if they endorsed experiencing hallucinations, were given the VOT during their brief neuropsychological evaluation, and were diagnosed with dementia or unspecified neurocognitive disorder. The patient’s electronic medical record was used to retrospectively gather additional details regarding their hallucinations and …


Employment Transitions From Active-Duty Army Officer To Civilian: An Exploration Of The Knowledge, Skills, And Abilities Possessed By Combat-Experienced, Army Field-Grade Officers, James Daniel Crook Dec 2022

Employment Transitions From Active-Duty Army Officer To Civilian: An Exploration Of The Knowledge, Skills, And Abilities Possessed By Combat-Experienced, Army Field-Grade Officers, James Daniel Crook

Theses and Dissertations

Two decades of wars in Iraq and Afghanistan have concluded, bringing an end to the longest military conflicts in the history of the United States of America. Following the example of post-war history, the military’s posture is to reduce personnel end-strength. The post-war military requires fewer soldiers, and a significant number of transitioning officers make the journey from military to civilian employment. This quantitative study discovered the knowledge, skills, and abilities of combat-experienced, active-duty, Army field-grade officers and explored the change from military to civilian employment. This study addressed the gap in the literature regarding this specific group of transitioning …


Towards Orchestration In The Cloud-Fog Continuum, Xavier Jesus Merino Aguilera Dec 2022

Towards Orchestration In The Cloud-Fog Continuum, Xavier Jesus Merino Aguilera

Theses and Dissertations

The proliferation of the Internet-of-Things has raised demand for computing, storage, and network resources. The cloud model is ill-equipped to handle the volume and variety of data travelling to and from the cloud’s core as more data is generated and consumed at the network’s edge. Some applications necessitate low-latency connectivity and geographical awareness, highlighting the cloud’s centralization shortcomings. By localizing resources, minimizing bandwidth utilization, and lowering latency, the fog and edge layers are proposed to circumvent these limitations. At these layers, resource orchestration is crucial because poor resource management has an impact on service delivery. The aim of this study …


Identifying Properties Of Blockchain Making It Relevant To Iot Applications, Ashwaq Alaklabi Dec 2022

Identifying Properties Of Blockchain Making It Relevant To Iot Applications, Ashwaq Alaklabi

Theses and Dissertations

Blockchain is a distributed ledger system that enables machine-to-machine interactions combined with the Internet of Things (IoT). It employs a series of transactions stored in a database, confirmed by numerous sources, and written into a shared ledger distributed across all nodes. The marriage of IoT with blockchain has several potential benefits, including the ability for a smart device to act autonomously without the need for a centralized authority. It can also monitor how devices communicate with one another. A blockchain network can track and sell almost anything of value, lowering risk and costs for everyone involved. Numerous applications from diverse …


The Effects Of Neuroticism And Treatment Delivery Modality On Therapeutic Outcomes In A Community Mental Health Training Clinic, Michelle Elizabeth Sibol Dec 2022

The Effects Of Neuroticism And Treatment Delivery Modality On Therapeutic Outcomes In A Community Mental Health Training Clinic, Michelle Elizabeth Sibol

Theses and Dissertations

The onset of the novel Coronavirus Disease 2019 (COVID-19) two and a half years prior to this writing resulted in shifts in everyday life, as individuals worldwide were required to shelter-in-place and abide by social distancing guidelines to slow the spread of the disease. This resulted in a marked increase in the utilization of virtual platforms (“teletherapy”) by mental health care providers, including training clinics, to continue providing therapy services to the community at large. Although the pandemic restrictions have lifted, adaptations made during shelter-in-place mandates remain, including provision of services via teletherapy platforms. The pandemic shed light on the …


Headache Disorders And Neurocognitive Performance Pre- And Post-Concussive Injury, Kaci Gorres Dec 2022

Headache Disorders And Neurocognitive Performance Pre- And Post-Concussive Injury, Kaci Gorres

Theses and Dissertations

Objective: The aim of this study is to examine the relationship between pre-existing headache disorders, such as headache or migraine, and neurocognitive testing obtained before and after college-athletes sustain a concussion. Method: A total of 1129 NCAA Division II college athletes from Florida Tech were included in the present study. Participants were included in this study if they completed baseline and/or post-trauma neuropsychological evaluations that included the Sports Concussion Assessment Tool – Fifth Edition (SCAT-5) and Immediate Post-Concussion Assessment and Cognitive Tool (ImPACT). Athletes’ headache and/or migraine history was self-reported at baseline and indicated their position in headache history or …


Efficacy And Safety Of Lifileucel, A One-Time Autologous Tumor-Infiltrating Lymphocyte (Til) Cell Therapy, In Patients With Advanced Melanoma After Progression On Immune Checkpoint Inhibitors And Targeted Therapies: Pooled Analysis Of Consecutive Cohorts Of The C-144-01 Study, Jason Chesney, Karl D Lewis, Harriet Kluger, Omid Hamid, Eric Whitman, Sajeve Thomas, Martin Wermke, Mike Cusnir, Evidio Domingo-Musibay, Giao Q Phan, John M Kirkwood, Jessica C Hassel, Marlana Orloff, James Larkin, Jeffrey Weber, Andrew J S Furness, Nikhil I Khushalani, Theresa Medina, Michael E Egger, Friedrich Graf Finckenstein, Madan Jagasia, Parameswaran Hari, Giri Sulur, Wen Shi, Xiao Wu, Amod Sarnaik Dec 2022

Efficacy And Safety Of Lifileucel, A One-Time Autologous Tumor-Infiltrating Lymphocyte (Til) Cell Therapy, In Patients With Advanced Melanoma After Progression On Immune Checkpoint Inhibitors And Targeted Therapies: Pooled Analysis Of Consecutive Cohorts Of The C-144-01 Study, Jason Chesney, Karl D Lewis, Harriet Kluger, Omid Hamid, Eric Whitman, Sajeve Thomas, Martin Wermke, Mike Cusnir, Evidio Domingo-Musibay, Giao Q Phan, John M Kirkwood, Jessica C Hassel, Marlana Orloff, James Larkin, Jeffrey Weber, Andrew J S Furness, Nikhil I Khushalani, Theresa Medina, Michael E Egger, Friedrich Graf Finckenstein, Madan Jagasia, Parameswaran Hari, Giri Sulur, Wen Shi, Xiao Wu, Amod Sarnaik

Department of Medical Oncology Faculty Papers

Background: Patients with advanced melanoma have limited treatment options after progression on immune checkpoint inhibitors (ICI). Lifileucel, a one-time autologous tumor-infiltrating lymphocyte (TIL) cell therapy, demonstrated an investigator-assessed objective response rate (ORR) of 36% in 66 patients who progressed after ICI and targeted therapy. Herein, we report independent review committee (IRC)-assessed outcomes of 153 patients treated with lifileucel in a large multicenter Phase 2 cell therapy trial in melanoma.

Methods: Eligible patients had advanced melanoma that progressed after ICI and targeted therapy, where appropriate. Melanoma lesions were resected (resected tumor diameter ≥1.5 cm) and shipped to a central good manufacturing …


High Local Control And Low Ocular Toxicity Using Ultra-Low-Dose “Boom-Boom” Radiotherapy For Indolent Orbital Lymphoma, Sanjna Shelukar, Christian Fernandez, Zeynep Bas, Lydia Komarnicky, Sara E. Lally, Carol L Shields, Adam Binder, Pierluigi Porcu, Onder Alpdogan, Ubaldo Martinez-Outschoorn, Wenyin Shi Dec 2022

High Local Control And Low Ocular Toxicity Using Ultra-Low-Dose “Boom-Boom” Radiotherapy For Indolent Orbital Lymphoma, Sanjna Shelukar, Christian Fernandez, Zeynep Bas, Lydia Komarnicky, Sara E. Lally, Carol L Shields, Adam Binder, Pierluigi Porcu, Onder Alpdogan, Ubaldo Martinez-Outschoorn, Wenyin Shi

Department of Medical Oncology Faculty Papers

Background: The first line definitive treatment for early-stage indolent B-cell lymphoma is radiation therapy (RT). Due to the sensitivity of orbital structures to radiation, ultra-low-dose RT (4 Gy in 2 fractions, "boom-boom") has and been utilized as an attractive option for orbital lymphoma. In this retrospective study, we evaluated the outcome and toxicity of "boom-boom" RT for indolent orbital lymphoma with an emphasis on ophthalmologic toxicity.

Methods: This is a retrospective case series with 17 patients with orbital lymphoma who received boom-boom RT at a single tertiary referral center between January 2017 and June 2022. Medical records, imaging and radiation …


How Well Do Your Family Members Know You? The Relationship Between Informant Report And Cognitive Performance Of Older Adults, Mairy Yousif Dec 2022

How Well Do Your Family Members Know You? The Relationship Between Informant Report And Cognitive Performance Of Older Adults, Mairy Yousif

Theses and Dissertations

Introduction: Given the clear impact and prevalence of dementia on the aging population, there is a need for greater research and understanding in this area. As the dementia progresses, medical providers rely heavily on caregiver and family member reports of the patient’s functioning and other aspects of their care. Therefore, it is important to know how accurate caregivers and family members are in judging their loved ones’ cognitive and physical strengths and weaknesses. This study aims to expand upon these previous studies by comparing caregiver/collateral reports of cognitive and functional status on the DSRS to neuropsychological tests and an objective …


On Clinical Use Of Infrared Cameras For Video-Based Estimation Of 3d Facial Kinematics, William Mackenzie Harrington Dec 2022

On Clinical Use Of Infrared Cameras For Video-Based Estimation Of 3d Facial Kinematics, William Mackenzie Harrington

Theses and Dissertations

Neurological and neurodegenerative disorders such as Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), and stroke can cause speech and orofacial motor impairments with devastating effects on quality of life. Analysis of orofacial movement provides vital information for early diagnosis and tracking disease progression, but current clinical practice relies on perceptual assessments performed by clinicians, which are unreliable and insensitive to early symptoms. New methods in machine learning have enabled automatic and objective assessment of orofacial kinematics from color and depth videos, hence we introduce MEADepthCamera, a mobile application for RGB-D video and audio recording and automatic estimation of 3D facial …


Color Resolved Cherenkov Imaging Allows For Differential Signal Detection In Blood And Melanin Content, Vihan A. Wickramasinghe Dec 2022

Color Resolved Cherenkov Imaging Allows For Differential Signal Detection In Blood And Melanin Content, Vihan A. Wickramasinghe

Dartmouth College Master’s Theses

Cherenkov imaging in radiation therapy allows a video display of the irradiation beam on the patient’s tissue, for visualization of the treatment. High energy radiation from a linear accelerator (Linac) results in the production of spectrally-continuous broadband light inside tissue due to the Cherenkov effect; this light is then attenuated by tissue features from transport and exits from the delivery site. Progress with the development of color Cherenkov imaging has opened the possibility for some level of spectroscopic imaging of the light-tissue interaction and interpretation of the specific nature of the tissue being irradiated. Generally, there is a linear relationship …


Divergent Serpentoviruses In Free-Ranging Invasive Pythons And Native Colubrids In Southern Florida, United States, Steven B. Tillis, Jillian M. Josimovich, Melissa A. Miller, Laura L. Hoon-Hanks, Arik M. Hartmann, Natalie M. Claunch, Marley E. Iredale, Tracey D. Logan, Amy A. Yackel Adams, Ian A. Bartoszek, John S. Humphrey, Bryan M. Kluever, Mark D. Stenglein, Robert N. Reed, Christina M. Romagosa, James F.X. Wellehan, Robert J. Ossiboff Dec 2022

Divergent Serpentoviruses In Free-Ranging Invasive Pythons And Native Colubrids In Southern Florida, United States, Steven B. Tillis, Jillian M. Josimovich, Melissa A. Miller, Laura L. Hoon-Hanks, Arik M. Hartmann, Natalie M. Claunch, Marley E. Iredale, Tracey D. Logan, Amy A. Yackel Adams, Ian A. Bartoszek, John S. Humphrey, Bryan M. Kluever, Mark D. Stenglein, Robert N. Reed, Christina M. Romagosa, James F.X. Wellehan, Robert J. Ossiboff

United States Department of Agriculture Wildlife Services: Staff Publications

Burmese python (Python bivittatus) is an invasive snake that has significantly affected ecosystems in southern Florida, United States. Aside from direct predation and competition, invasive species can also introduce nonnative pathogens that can adversely affect native species. The subfamily Serpentovirinae (order Nidovirales) is composed of positive-sense RNA viruses primarily found in reptiles. Some serpentoviruses, such as shingleback nidovirus, are associated with mortalities in wild populations, while others, including ball python nidovirus and green tree python nidovirus can be a major cause of disease and mortality in captive animals. To determine if serpentoviruses were present in invasive Burmese …


Mitochondrial Functions Are Major Targets Of Isocyanide Activity In Saccharomyces Cerevisiae, Morgan A. Siemek Dec 2022

Mitochondrial Functions Are Major Targets Of Isocyanide Activity In Saccharomyces Cerevisiae, Morgan A. Siemek

School of Biological Sciences: Dissertations, Theses, and Student Research

The isocyanide functional group is important in the synthesis of many organic compounds and is found in natural products produced by plants, bacteria, marine invertebrates, and fungi. The antimicrobial activities of isocyanide compounds have been documented for almost 70 years, however, the biochemical targets and mechanisms of action remain poorly defined. We report antimicrobial activity of 4-para-nitrophenyl-isocyanide (p-NPIC) against a model fungus, Saccharomyces cerevisiae, and the human fungal pathogen Candida albicans. To identify the cellular and molecular targets of p-NPIC, we screened the non-essential single gene-deletion collection of S. cerevisiae. We …


Environmental Determination Of Gastrointestinal Parasitism In Katahdin Sheep, Brian Arisman Dec 2022

Environmental Determination Of Gastrointestinal Parasitism In Katahdin Sheep, Brian Arisman

Department of Animal Science: Dissertations, Theses, and Student Research

Gastrointestinal nematodes (GIN) negatively affect the performance and wellbeing of sheep and are difficult to control due to anthelmintic resistance. Producers are therefore choosing breeds naturally resistant to GIN infection, such as the Katahdin. Katahdin are raised in various climates and management systems in the U.S., and those environmental factors can be combined into eco-management clusters. We hypothesized that GIN challenge varies predictably based on the characteristics of these clusters. Katahdin producers from across the U.S. were surveyed for management information. Body weights (BW), fecal egg counts (FEC) and FAMACHA scores (FAM) were collected on 3,527 Katahdin lambs around 90 …


Essential Property, Timothy M. Mulvaney, Joseph William Singer Dec 2022

Essential Property, Timothy M. Mulvaney, Joseph William Singer

Faculty Scholarship

For a sizable swath of the U.S. population, incomes and wealth are insufficient to cover life’s most basic necessities even in the most ordinary of times. A disturbingly resilient explanation for this state of affairs rests on the view that resource inequities are avoidable through self-reliance, a stance that invites observers to see people in poverty as morally suspect. This Article advances a counterview in contending that the widespread lack of essential resources did not simply arise naturally via individuals’ life choices but instead has been, in very meaningful part, created and perpetuated by our system of property laws.

The …


Bilingual Advantages To The Construction Industry, Miguel A. Duran Jr. Dec 2022

Bilingual Advantages To The Construction Industry, Miguel A. Duran Jr.

Construction Management

The purpose of this paper is to analyze and emphasize the importance of the Spanish language within the construction industry to construction management students at Cal Poly. Knowledge within another language is also used at an advantage in the industry as it increases one’s value through this key skill, and aids effective team communication on a project. Furthermore, the construction industry is filled with subcontractor’s majority being of Latin-based descent. Though this key skill is not required by companies, this skill can help verbal communication barriers which occur on a project when most subcontractors only speak the Spanish language. Verbal …


Technological Integration To Enhance Jobsite Safety, Luke Barragan Dec 2022

Technological Integration To Enhance Jobsite Safety, Luke Barragan

Construction Management

The content derived in this paper portrays the effect that technology has on safety and how it may be enhanced and altered in the built environment. Ensuring safety on the jobsite is the most important aspect of concluding a successful project. Alongside safety on the jobsite is technology, both of which work coherently together to ensure proper construction. Technology has advanced tremendously in the built environment and it is difficult for all aspects of the project to be up to date universally. Safety lacks the technological integration that is found in the design and preconstruction phases of a project. There …