Digital Commons Network^™

Neutrosophic Linguistic Scale In The Assessment Of Knowledge Of Psychosomatic Medicine In University Students, Walter Alberto Vayas Valdiviezo, Lester Wong Vázquez, Francisco Xavier Poveda Paredes

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Statistical Analysis Of Self-Assessment Of Rehabilitation Knowledge In University Students, Elizabeth Cristina Mayorga Aldaz, Rosita Elizabeth Olivo Torres, Silvia Tatiana Tite Andi, Flor Betzabet Morocho Quinchuela

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Analysis Of Risk Factors In The Etiology Of Cerebral Palsy, Piedad Elizabeth Acurio Padilla, Andrés Eduardo Gallegos Cobo, Blanca Cristina Estrella López

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Cognitive Maps For The Analysis Of The Factors In The Proper Diagnosis Of Conversion Disorder, Jenny Olivia Caicedo Rodríguez, Álvaro Paúl Moina Veloz, Silvia Tatiana Tite Andi

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Linguistic Scale For The Assessment Of Knowledge Of Natural And Traditional Medicine In Dental Students, Rolando Manuel Benites, Jorge David Morales Cobos, Javier Estuardo Sánchez Sánchez

Neutrosophic Sets and Systems

No abstract provided.

Relevance Of The Obstacles To The Achievement Of Food Sovereignty In Ecuador, Analysis Through The Neutrosophic Soft Set, Tannia Cristina Poveda Morales, Silvia Elizabeth Bonilla Veloz, Diego Armando Freire Muñoz

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Analysis Of Nutritional Orientation In University Students, María Gabriela Balarezo García, Andrés Eduardo Gallegos Cobo, Miguel Eduardo Ramos Argilagos

Neutrosophic Sets and Systems

No abstract provided.

Conducive Factors Of Adolescent Pregnancy In Ecuador Through Neutrosophic Statistics, Lenin Carlos Gabriel Flores, Iruma Alfonso Gonzáles, Kenia Mariela Peñafiel Jaramillo, Olga Cristina Solis Solis

Neutrosophic Sets and Systems

No abstract provided.

Analysis Of The Right To Monetary Contribution For Illness Through Neutrosophic Statistics, Manaces Esaud Gaspar Santos, Nelson Francisco Freire Sánchez, Javier Dario Bosquez Remache, Manuel Ricardo Velázquez

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Analysis Of The Irrational Exploitation Of Natural Resources, María Lorena Merizalde Avilés, Sheila Belén Esparza Pijal, Milton Rodrigo Hidalgo Ruiz, Simón Bolívar Gallegos Gallegos

Neutrosophic Sets and Systems

No abstract provided.

Application Of Neutrosophy In The Study Of The Factors That Influence Ecuadorian Tourism Development, Sharon Diznarda Álvarez Gómez, Ariel José Romero Fernández, Manuel Ricardo Rivas Bravo

Neutrosophic Sets and Systems

No abstract provided.

An Empirical Study On The Types Of Consumers And Their Preferences For E-Waste Recycling With A Points System, Hua Zhong, Shan Zhou, Zhiyao Zhao, Hao Zhang, Jing Nie, Palizhati Simayi

Michigan Tech Publications, Part 1

Improper disposal of electronical waste (e-waste) causes harm to both public health and the environment, and how to effectively recycle and reduce electronical waste has become a common concern around the world. This study focuses on the design of the points system to encourage consumer participation in e-waste recycling programs. Based on the Theory of Planned Behavior (TPB) model, a semi-experimental design method was applied to influence consumer cognition and behavioral intention through information provision in survey design. Two surveys were conducted in two years apart to understand the temporal trend of consumer types and their preferences for the design …

Diagnosing Covid-19 Infection In Chest X-Ray Images Using Neural Network, Salim M. Zaki, Mustafa Musa Jaber, Mohammed A. Kashmoola

Baghdad Science Journal

With its rapid spread, the coronavirus infection shocked the world and had a huge effect on billions of peoples' lives. The problem is to find a safe method to diagnose the infections with fewer casualties. It has been shown that X-Ray images are an important method for the identification, quantification, and monitoring of diseases. Deep learning algorithms can be utilized to help analyze potentially huge numbers of X-Ray examinations. This research conducted a retrospective multi-test analysis system to detect suspicious COVID-19 performance, and use of chest X-Ray features to assess the progress of the illness in each patient, resulting in …

Effectiveness Of Non-Invasive Respiratory Support Strategies In Patients With Covid-19: A Systematic Review And Meta Analysis, Vinesh Kumar, Umair Arshad Malik, Reshman Kumari, Berkha Berkha, Vijay Kumar, Manoj Kumar, Simran Simran, Suman Suman, Bushra Nasim

Medical College Documents

Background: The effectiveness of non-invasive respiratory strategies, namely CPAP and HFNO, in reducing the risk of mortality and tracheal intubation in patients with severe COVID-19 is not well established.
Methods: A thorough literature search was conducted across 3 electronic databases (Medline, EMBASE and Cochrane Central) from inception through July 2022. Randomized controlled trials (RCTs) and observational studies assessing the impact of CPAP or HFNO on clinical outcomes in patients infected with COVID-19 were considered for inclusion. End-points included all-cause mortality and risk of tracheal intubation. Evaluations were reported as risk ratios (RRs) with 95% confidence intervals (CI) and analysis was …

Consensus Subtypes Of Hepatocellular Carcinoma Associated With Clinical Outcomes And Genomic Phenotypes, Sung Hwan Lee, Sun Young Yim, Yun Seong Jeong, Qi-Xiang Li, Sang-Hee Kang, Bo Hwa Sohn, Shwetha V Kumar, Ji-Hyun Shin, You Rhee Choi, Jae-Jun Shim, Hayeon Kim, Ji Hoon Kim, Shin Kim, Sheng Guo, Randy L Johnson, Ahmed Kaseb, Koo Jeong Kang, Yun Shin Chun, Hee Jin Jang, Byoung Gill Lee, Hyun Goo Woo, Min Jin Ha, Rehan Akbani, Lewis R Roberts, David A Wheeler, Ju-Seog Lee

Faculty, Staff and Student Publications

BACKGROUND AND AIMS: Although many studies revealed transcriptomic subtypes of HCC, concordance of the subtypes are not fully examined. We aim to examine a consensus of transcriptomic subtypes and correlate them with clinical outcomes.

APPROACH AND RESULTS: By integrating 16 previously established genomic signatures for HCC subtypes, we identified five clinically and molecularly distinct consensus subtypes. STM (STeM) is characterized by high stem cell features, vascular invasion, and poor prognosis. CIN (Chromosomal INstability) has moderate stem cell features, but high genomic instability and low immune activity. IMH (IMmune High) is characterized by high immune activity. BCM (Beta-Catenin with high Male …

Structural Variants Drive Context-Dependent Oncogene Activation In Cancer, Zhichao Xu, Dong-Sung Lee, Sahaana Chandran, Victoria T Le, Rosalind Bump, Jean Yasis, Sofia Dallarda, Samantha Marcotte, Benjamin Clock, Nicholas Haghani, Chae Yun Cho, Kadir C Akdemir, Selene Tyndale, P Andrew Futreal, Graham Mcvicker, Geoffrey M Wahl, Jesse R Dixon

Faculty, Staff and Student Publications

Higher-order chromatin structure is important for the regulation of genes by distal regulatory sequences. Structural variants (SVs) that alter three-dimensional (3D) genome organization can lead to enhancer-promoter rewiring and human disease, particularly in the context of cancer3. However, only a small minority of SVs are associated with altered gene expression4,5, and it remains unclear why certain SVs lead to changes in distal gene expression and others do not. To address these questions, we used a combination of genomic profiling and genome engineering to identify sites of recurrent changes in 3D genome structure in cancer and determine the effects of specific …

Pan-Cancer Landscape Of Aid-Related Mutations, Composite Mutations, And Their Potential Role In The Ici Response, Isaias Hernández-Verdin, Kadir C Akdemir, Daniele Ramazzotti, Giulio Caravagna, Karim Labreche, Karima Mokhtari, Khê Hoang-Xuan, Matthieu Peyre, Franck Bielle, Mehdi Touat, Ahmed Idbaih, Alex Duval, Marc Sanson, Agustí Alentorn

Faculty, Staff and Student Publications

Activation-induced cytidine deaminase, AICDA or AID, is a driver of somatic hypermutation and class-switch recombination in immunoglobulins. In addition, this deaminase belonging to the APOBEC family may have off-target effects genome-wide, but its effects at pan-cancer level are not well elucidated. Here, we used different pan-cancer datasets, totaling more than 50,000 samples analyzed by whole-genome, whole-exome, or targeted sequencing. AID mutations are present at pan-cancer level with higher frequency in hematological cancers and higher presence at transcriptionally active TAD domains. AID synergizes initial hotspot mutations by a second composite mutation. AID mutational load was found to be independently associated with …

A Phase Ii, Multicenter, Open-Label, Randomized Trial Of Pegfilgrastim For Patients With Alcohol-Associated Hepatitis, John A Tayek, Andrew A Stolz, Danh V Nguyen, M Wayne Fleischman, John A Donovan, Joseph M Alcorn, Daniel C-K Chao, Aliya Asghar, Timothy R Morgan, Southern California Alcoholic Hepatitis (Scah) Consortium

Faculty, Staff and Student Publications

BACKGROUND: In trials conducted in India, recombinant granulocyte colony stimulating factor (GCSF) improved survival in alcohol-associated hepatitis (AH). The aim of this trial was to determine the safety and efficacy of pegfilgrastim, a long-acting recombinant GCSF, in patients with AH in the United States.

METHODS: This prospective, randomized, open label trial conducted between March 2017 and March 2020 randomized patients with a clinical diagnosis of AH and a Maddrey discriminant function score ≥32 to standard of care (SOC) or SOC+pegfilgrastim (0.6 mg subcutaneously) on Day 1 and Day 8 (clinicaltrials.gov NCT02776059). SOC was 28 days of either pentoxifylline or prednisolone, …

Spinal Metastases And The Evolving Role Of Molecular Targeted Therapy, Chemotherapy, And Immunotherapy, Elena I Fomchenko, James C Bayley, Christopher Alvarez-Breckenridge, Laurence D Rhines, Claudio E Tatsui

Faculty, Staff and Student Publications

Metastatic involvement of the spine is a common complication of systemic cancer progression. Surgery and external beam radiotherapy are palliative treatment modalities aiming to preserve neurological function, control pain and maintain functional status. More recently, with development of image guidance and stereotactic delivery of high doses of conformal radiation, local tumor control has improved; however recurrent or radiation refractory disease remains a significant clinical problem with limited treatment options. This manuscript represents a narrative overview of novel targeted molecular therapies, chemotherapies, and immunotherapy treatments for patients with breast, lung, melanoma, renal cell, prostate, and thyroid cancers, which resulted in improved …

Massive Macroglossia, A Rare Side Effect Of Covid-19: Clinical, Histologic, And Genomic Findings In Covid-19-Positive Versus Covid-19-Negative Patients, Victoria A Mañón, David Chubb, Laura S Farach, Rachid Karam, Mary C Farach-Carson, Nadarajah Vigneswaran, Karan Saluja, Simon Young, Mark Wong, James C Melville

Faculty, Staff and Student Publications

PURPOSE: The primary purpose of this study is to identify if there is an underlying genetic predisposition for COVID-related macroglossia and if this susceptibility is higher among individuals of African heritage. Secondary objectives include determining if genetic testing of COVID-infected patients who are intubated and prone could identify patients with higher susceptibility to the development of macroglossia.

METHODS: A retrospective chart review was completed for each patient, and prospectively, genetic and histopathologic analyses were completed. Whole-exome sequencing was completed on two patients; immunohistochemistry was completed on the COVID-positive tissue samples.

RESULTS: Histopathology of the COVID-positive patient revealed significant peri-lymphocytic infiltrate, …

Safety And Efficacy Of Hsp90 Inhibitor Ganetespib For Neoadjuvant Treatment Of Stage Ii/Iii Breast Cancer, Julie E Lang, Andres Forero-Torres, Douglas Yee, Christina Yau, Denise Wolf, John Park, Barbara A Parker, A Jo Chien, Anne M Wallace, Rashmi Murthy, Kathy S Albain, Erin D Ellis, Heather Beckwith, Barbara B Haley, Anthony D Elias, Judy C Boughey, Rachel L Yung, Claudine Isaacs, Amy S Clark, Hyo S Han, Rita Nanda, Qamar J Khan, Kristen K Edmiston, Erica Stringer-Reasor, Elissa Price, Bonnie Joe, Minetta C Liu, Lamorna Brown-Swigart, Emanuel F Petricoin, Julia D Wulfkuhle, Meredith Buxton, Julia L Clennell, Ashish Sanil, Scott Berry, Smita M Asare, Amy Wilson, Gillian L Hirst, Ruby Singhrao, Adam L Asare, Jeffrey B Matthews, Michelle Melisko, Jane Perlmutter, Hope S Rugo, W Fraser Symmans, Laura J Van 'T Veer, Nola M Hylton, Angela M Demichele, Donald A Berry, Laura J Esserman

Faculty, Staff and Student Publications

HSP90 inhibitors destabilize oncoproteins associated with cell cycle, angiogenesis, RAS-MAPK activity, histone modification, kinases and growth factors. We evaluated the HSP90-inhibitor ganetespib in combination with standard chemotherapy in patients with high-risk early-stage breast cancer. I-SPY2 is a multicenter, phase II adaptively randomized neoadjuvant (NAC) clinical trial enrolling patients with stage II-III breast cancer with tumors 2.5 cm or larger on the basis of hormone receptors (HR), HER2 and Mammaprint status. Multiple novel investigational agents plus standard chemotherapy are evaluated in parallel for the primary endpoint of pathologic complete response (pCR). Patients with HER2-negative breast cancer were eligible for randomization to …

Secure Human Action Recognition By Encrypted Neural Network Inference, Miran Kim, Xiaoqian Jiang, Kristin Lauter, Elkhan Ismayilzada, Shayan Shams

Faculty Research, Scholarly, and Creative Activity

Advanced computer vision technology can provide near real-time home monitoring to support “aging in place” by detecting falls and symptoms related to seizures and stroke. Affordable webcams, together with cloud computing services (to run machine learning algorithms), can potentially bring significant social benefits. However, it has not been deployed in practice because of privacy concerns. In this paper, we propose a strategy that uses homomorphic encryption to resolve this dilemma, which guarantees information confidentiality while retaining action detection. Our protocol for secure inference can distinguish falls from activities of daily living with 86.21% sensitivity and 99.14% specificity, with an average …

The Flavor Profiles Of Highland Barley Fermented With Different Mushroom Mycelium, Kai Wang, Cuicui Yang, Ziyan Dai, Zhenxiang Wen, Yin Liu, Xi Feng, Ying Liu, Wen Huang

Faculty Research, Scholarly, and Creative Activity

Highland barley was fermented with Cordyceps militaris, Stropharia rugoso-annulata, Morchella esculenta, Schizophyllum commune and Tremella sanguinea. The flavor profiles were investigated by electronic nose (E-nose), headspace solid-phase microextraction gas chromatography-mass spectrometry (HS-SPME-GC-MS) and sensory evaluation by train panel. Fermentation with mushroom mycelium was able to change the aroma profile of highland barley. The original strong grassy taste was reduced due to a decrease in hexanal, decanal and 2-pentylfuran, and new aromatic flavors (floral, sweet and mushroom fragrance) were acquired after fermentation. The overall flavor of the fermented highland barley varied with mushroom strains. Schizophyllum commune gave a heavier sour taste …

Psychometric Evaluation Of The Muscle Dysmorphic Disorder Inventory (Mddi) Among Gender-Expansive People, Emilio J. Compte, Chloe J. Cattle, Jason M. Lavender, Tiffany A. Brown, Stuart B. Murray, Matthew R. Capriotti, Annesa Flentje, Micah E. Lubensky, Juno Obedin-Maliver, Mitchell R. Lunn, Jason M. Nagata

Faculty Research, Scholarly, and Creative Activity

Purpose: Muscle dysmorphia is generally classified as a specific form of body dysmorphic disorder characterized by a pathological drive for muscularity and the preoccupation that one is too small or not sufficiently muscular. The majority of research on the condition has been conducted in cisgender men with a paucity of literature on gender minority people, a population that is at risk for muscle dysmorphia. One of the most widely used measures of muscle dysmorphia symptoms, the Muscle Dysmorphic Disorder Inventory (MDDI), has not been psychometrically validated for use in gender minority samples, the aim of the present study. Methods: We …

Healthcare Mistreatment, State-Level Policy Protections, And Healthcare Avoidance Among Gender Minority People, Kristen D. Clark, Sean Luong, Mitchell R. Lunn, Elena Flowers, Esmaeil Bahalkeh, Micah E. Lubensky, Matthew R. Capriotti, Juno Obedin-Maliver, Annesa Flentje

Faculty Research, Scholarly, and Creative Activity

Introduction: This study examined whether past experiences of mistreatment in healthcare were associated with greater healthcare avoidance due to anticipated mistreatment among gender minority (GM) people. We evaluated whether state-level healthcare policy protections moderated this relationship. Methods: Data from the 2018 Annual Questionnaire of The PRIDE Study, a national longitudinal study on sexual and gender minority people’s health, were used in these analyses. Logistic regression modeling tested relationships between lifetime healthcare mistreatment due to gender identity or expression and past-year healthcare avoidance due to anticipated mistreatment among GM participants. Interactions between lifetime healthcare mistreatment and state-level healthcare policy protections and …

Leaving More Than Footprints: Anthropogenic Nutrient Subsidies To A Protected Area, A. S. Guerra, A. Bui, M. Klope, D. A. Orr, S. A. Shaffer, H. S. Young

Faculty Research, Scholarly, and Creative Activity

Mobile animals that traverse ecosystem boundaries can fundamentally reshape environments by providing critical nutrient and energy inputs to the ecosystems they inhabit. In particular, aggregations of seabirds often transform coastal and island ecosystems through large amounts of nutrient-rich guano deposition. Anthropogenically driven losses of these subsidies can occur through changes in abundance of mobile species, including seabirds, and have been shown to drive whole-scale ecosystem state change on islands. However, even though many species that forage on anthropogenic food sources are highly mobile and may thus play important roles in moving nutrients from urban systems to otherwise conserved ecosystems, the …

Diabetes Family-Inclusion Education In The Outpatient Clinic, Sheryl Lyn Wright

Electronic Theses and Dissertations

Patient education is critical for the regulation of Type II Diabetes. This study evaluated 39 adults ≥ 40 years old with T2D and a HgbA1c level of ≥ 7.0%, including 27 women and 12 men aged 40 to 74. The participants were divided into two separate groups. The first group (19) diagnosed with T2D had no formal disease management education but were given videos on diabetes education to watch alone. The second group (202) was given family-inclusion diabetes education through videos. The hypothesis was that individuals who watched educational videos with family would have a more significant HgbA1c decrease than …

Best Practices In Disaster Public Communications: Evacuation Alerting And Social Media, Frannie Edwards, Kaikai Liu, Amanda Lee Hughes, Jerry Zeyo Gao, Dan Goodrich, Alan Barner, Robert Herrera

Mineta Transportation Institute

This research project examines the current state of the practice for disaster public communication, the distrust of government, the training available to public information officers, and the literature available to guide the design of effective public outreach messaging, especially for rapid on-set events. Growing distrust in government had led to lack of public confidence in public agency messaging during emergencies, yet public agency public information officers are using multiple pathways, including both traditional and social media resources, to try to reach impacted communities effectively. The introduction explains the development of wildfire events in the West and their context. A literature …

Financial Literacy Among Buffalo State College Undergraduate Students, Toni Martinucci

Public Administration Master’s Projects

Financial literacy can be complex and difficult for college students to comprehend. Many students struggle to afford college and are faced with large amounts of student loan debt. Financial awareness needs to be addressed early on for students to make informed decisions about college costs, student debt, and financial aid. However, financial aid applications, terms and conditions, and eligibility requirements are difficult for many students to comprehend on their own. The purpose of this study is to access financial literacy among undergraduate students at Buffalo State College. A quantitative approach is used in this study by implementing a web-based cross-sectional …

Perception Of Police And The Mediation Of Memory Distortion Via Trauma: Body Worn Camera Footage Of An Emotional Police-Citizen Encounter, Arlyn Abreu

Student Theses

This present study calls to question the objectivity of police body-worn camera (BWC) footage. Proponents assume that BWCs will be a panacea in a climate of heightened tensions between officers and communities. In spite of this, our findings challenge the rhetoric, and the purpose BWC is intended to serve. We explored its implications on memory distortion by posing two questions (a) can people come to remember BWC footage as more traumatic than they initially experienced (b) to what degree can external information and internal influences impact peoples' judgment about a traumatic event. We addressed both questions in this two-part study, …