Digital Commons Network^™

The Use Of Virtual Reality As A Standard Of Care In Verified Burn Centers, Emily Werner

Nursing Masters

This study explored whether the use of virtual reality (VR) was a standard of care during burn care at burn verified facilities in the United States. Surveys were sent to American Burn Association verified burn centers to investigate if VR was being used as a standard of care, if protocols for using VR are in place and how they were developed, and what barriers these facilities are facing and several other topics investigated. Out of the 64 facilities surveyed, 21 responses were collected. Burn facilities reported 63.2% do not use and 36.8% do use VR while performing burn dressing changes …

The Circadian Nobiletin-Ror Axis Suppresses Adipogenic Differentiation And Iκbα/Nf-Κb Signaling In Adipocytes, Ji Ye Lim, Eunju Kim, Collin M Douglas, Marvin Wirianto, Chorong Han, Kaori Ono, Sun Young Kim, Justin H Ji, Celia K Tran, Zheng Chen, Karyn A Esser, Seung-Hee Yoo

Faculty, Staff and Student Publications

Numerous molecular and physiological processes in the skeletal muscle undergo circadian time-dependent oscillations in accordance with daily activity/rest cycles. The circadian regulatory mechanisms underlying these cyclic processes, especially at the post-transcriptional level, are not well defined. Previously, we reported that the circadian E3 ligase FBXL21 mediates rhythmic degradation of the sarcomere protein TCAP in conjunction with GSK-3β, and Psttm mice harboring an Fbxl21 hypomorph allele show reduced muscle fiber diameter and impaired muscle function. To further elucidate the regulatory function of FBXL21 in skeletal muscle, we investigated another sarcomere protein, Myozenin1 (MYOZ1), that we identified as an FBXL21-binding protein from …

Endovascular Repair Of Aortic Arch Graft Pseudoaneurysm Using A Duct Occluder Device With Onlay Fusion Guidance, Guilherme B Barbosa Lima, Laura Ocasio, Emanuel R Tenorio, Marina Dias-Neto, Thanila A Macedo, Gustavo S Oderich

Faculty, Staff and Student Publications

Aortic arch pseudoaneurysms can be caused by previous surgery, infection, or trauma. In select patients with small tears and no evidence of infection, local repair can be performed using an open or endovascular technique.1 Open surgical repeat surgery has increased risks and endovascular repair has been especially appealing for the elderly, higher risk patients, and patients with multiple prior procedures.2 We have reported the use of a ductal occluder device in a patient with a large aortic arch pseudoaneurysm.3 Our patient has provided written informed consent for the report of his case details and imaging studies.

Hypothesis Testing And Parameter Estimation In Mixture Cure Models For Cancer Survival Data, Mohammod Mahmudur Rahman

Graduate Theses and Dissertations

In oncology clinical trials, when a treatment is administered to the patient population, a certain subset of patients may respond to the treatment while the other does not. The positive responders with long-term survival are considered “statistically cured” and can be referred to as cured patients or long-term survivors. When a proportion of patients achieve long-term survival, the hazard functions of two arms (control vs. treatment) are no longer proportional. As a result, the traditional log-rank test, which is the most popular test to evaluate the effectiveness of a treatment in clinical trials, tends to lose its power. In this …

Bcl11b And Atoh8 Coordinate Cellular Plasticity For Reprogramming And Transformation, Mo-Fan Huang, Rachel Shoemaker, Dung-Fang Lee

Faculty, Staff and Student Publications

By dissecting and comparing the transcriptional trajectories and epigenomic traits of reprogramming and transforming cells at the single-cell resolution, Huyghe et al discovered Bcl11b and Atoh8, two key transcription factors controlling cell plasticity during pluripotent reprogramming and oncogenic transformation.

Defective Synaptic Plasticity In A Model Of Coffin-Lowry Syndrome Is Rescued By Simultaneously Targeting Pka And Mapk Pathways, Rong-Yu Liu, Yili Zhang, Paul Smolen, Leonard J Cleary, John H Byrne

Faculty, Staff and Student Publications

Empirical and computational methods were combined to examine whether individual or dual-drug treatments can restore the deficit in long-term synaptic facilitation (LTF) of the Aplysia sensorimotor synapse observed in a cellular model of Coffin–Lowry syndrome (CLS). The model was produced by pharmacological inhibition of p90 ribosomal S6 kinase (RSK) activity. In this model, coapplication of an activator of the mitogen-activated protein kinase (MAPK) isoform ERK and an activator of protein kinase A (PKA) resulted in enhanced phosphorylation of RSK and enhanced LTF to a greater extent than either drug alone and also greater than their additive effects, which is termed …

2022-12-00 Newsletter, Morehead State University. Staff Congress.

Staff Congress Records

Staff Congress newsletter from December of 2022.

We Can Help You Host Events/Conferences Content, Alice Sherwood

TMC Library Newsletter (2015-)

Did you know that the TMC Library can help you with the review process, acceptance of speakers, event advertisement, registration, and finally the archiving of materials from the event?

New Exhibit In The Library Street Level, Sandra Yates

TMC Library Newsletter (2015-)

Visit the TMC Library Street Level so you can check out the exhibit in the large case between the two classrooms. This seasonal exhibit features materials from the McGovern Historical Center’s San Jacinto Lung Association Records. During the holidays they would sell Christmas Seals to fund their efforts in fighting tuberculosis.

The Ford Foundation’S Work To Build The Field Of Impact Investing, Margot Brandenburg, Abeda Iqbal

The Foundation Review

Impact investing has grown dramatically over the past 15 years, with foundations playing a critical role through their program-related and, increasingly, mission-related investments. A smaller number, including the Ford Foundation, have dedicated grant and other programmatic resources toward growing the field. Without this funding, the metrics, engagement, policies, and norms needed to underpin capital markets at scale will be slow to materialize.

This article looks back at the long history of aligning financial investments with social values; touches on the Ford Foundation’s pioneering role in the emergence of PRIs as a tool to stretch grantmaking budgets; and details the impact …

A Promising Place-Based Collaborative Impact Investing Fund Strengthens Community And Informs Philanthropic Practice, Benjamin Kerman, Clara Miller

The Foundation Review

A recent evaluation of the Western New York Impact Investment Fund adds to the proof-of-concept literature regarding “doing good and doing well” while pointing to experience-based best practices in philanthropic impact investing. Born of a collaboration between regional and national philanthropies, the fund brings together corporate, individual, and philanthropic investors to deliver an inclusive impact investment mechanism. Founded in 2017, the fund evolved from concept to operating entity, focusing on mitigating capital gaps, longterm economic decline, and wealth divides.

Evaluation at Year 5 describes how the professionally managed, collaboratively governed fund has attracted and deployed capital, contributing to ecosystem improvements …

Implementation Of Sic Power Electronics For Green Energy Based Electrification Of Transportation, Naireeta Deb

All Dissertations

Increase in greenhouse gas emission poses a threat to the quality of air thus threatening the future of living beings on earth. A large part of the emission is produced by transport vehicles. Electric vehicles (EVs) are a great solution to this threat. They will completely replace the high usage of hydrocarbons in the transport sector. Energy efficiency and reduced local pollution can also be expected with full implementation of electrification of transportation. However, the current grid is not prepared to take the power load of EV charging if it were to happen readily. Moreover, critics are doubtful about the …

X-Ray Interrogated Implantable Chemical And Strain Sensors For Monitoring Implant Associated Infections And Fracture Healing, Apeksha Rajamanthrilage

All Dissertations

Bone fracture healing includes complex and sequence of dynamic events to restore the integrity and biomechanical properties of the bone. While most of the fractures heal without any problem, healing is sometimes compromised. Two significant fracture healing complications are orthopedic implant-associated infections and non-unions/delayed union. These can be interrelated causes as well. Implant-associated infection can cause implant loosening, and as a result, it can delay the fracture healing process. Herein, we describe two different types of sensors that can be used in monitoring biochemical and biomechanical processes of fracture healing using X-rays.

We developed a XELCI (X-ray Excited Luminescence Chemical …

Modeling, Control And Estimation Of Reconfigurable Cable Driven Parallel Robots, Adhiti Raman Thothathri

All Dissertations

The motivation for this thesis was to develop a cable-driven parallel robot (CDPR) as part of a two-part robotic device for concrete 3D printing. This research addresses specific research questions in this domain, chiefly, to present advantages offered by the addition of kinematic redundancies to CDPRs. Due to the natural actuation redundancy present in a fully constrained CDPR, the addition of internal mobility offers complex challenges in modeling and control that are not often encountered in literature.

This work presents a systematic analysis of modeling such kinematic redundancies through the application of reciprocal screw theory (RST) and Lie algebra while …

Empowering Older Adults With Their Information Privacy Management, Reza Ghaiumy Anaraky

All Dissertations

Literature depicts a deficit-based narrative around older adults and their technology use, suggesting that older adults are not able to keep up with their younger counterparts in adopting new technologies. In this dissertation, I argue that this view is not necessarily accurate or productive. Instead, I argue that the deficit is in the technology design, which is not inclusive and often caters to the needs of younger adults.

I study older and younger adults' privacy decision-making as a showcase. To study the privacy decision-making process with more granularity, I used a dual-route approach (decision heuristics and privacy calculus) to disentangle …

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The Impact Of Funds Of Knowledge On Elementary Multilingual Learners’ Perceptions Of Their Connection To Their Teacher And The Classroom, Kelli Lowe

All Dissertations

The U.S. population is rapidly becoming more culturally and linguistically diverse, and the education system is ill-equipped to meet the needs of these diverse learners thus creating large achievement gaps. In South Carolina, two factors contributing to an inadequate education system are the lack of teacher preparation programs that address cultural diversity and a predominantly White teacher workforce for an ever-growing diverse student body. The combination of these two factors is particularly detrimental to multilingual learners in the most critical time of a child’s development. This qualitative study was part of a collaboration and combined improvement science with design thinking …

Building Teachers’ Cultural Capital In The Classroom: Using Funds Of Knowledge To Support Multilingual Learners, Lindsey Skirtich

All Dissertations

This qualitative study has a collaborative focus and blends improvement science with Design Thinking to first understand teachers’ perceptions of their ability to serve ML students and second, how the utilization of the Funds of Knowledge (FoK) can assist teachers in serving ML students. The purpose of this study is to use the Funds of Knowledge to build the capacity of teachers to connect with students through their lived experiences.

Through collaboration and reflection, this study investigated teachers’ perceptions and focused on increasing teachers’ ability to serve ML students utilizing a framework intended to connect students’ backgrounds to the classroom.

Investigating Spatial Heterogeneity In Myocardial Wound Environments To Improve Therapy, Michael Potter

All Dissertations

Heart failure is a broad pathology manifestation categorized by an inability of the heart to successfully pump blood throughout the vast vessel network of the body. Within the United States, heart failure is projected to increase by approximately 46% from 2012 to 2030. Modalities of heart failure are generally related to wall mechanics that are impacted following myocardial infarction events. Interplay exists between the wall mechanics, responding cell populations, and the spatial heterogeneities in the resultant scar. This interplay directs the myocardium towards heart failure modalities governed by overly stiff or compliant states. It is essential to elucidate details underlying …

Activating Cosmic Capital: Evaluating The Role Of Social Capital And Sense Of Place In Environmental Stewardship And Adaptive Governance, Andrew Waters

All Dissertations

Adaptive natural resource governance strives to connect individuals and groups at multiple governance levels to organize as social networks that can draw on diverse experiences and knowledge to address complex natural resource and environmental challenges. To facilitate these networks, adaptive governance approaches emphasize collaborative stakeholder processes and social-ecological perspectives. However, the diverse opinions, backgrounds, and values in stakeholder process create their own challenges for effective and efficient solutions. Social capital and sense of place have emerged as prominent theoretical constructs to help explain cognitive process and behaviors in social-ecological networks. This dissertation explores the intersection of these two theoretical paradigms, …

Cross-Modal Associations Between Hand-Feel Touch And Oral Irritation, Ragita Cantika Pramudya

Graduate Theses and Dissertations

Hand-feel touch cues have been shown to influence the perception of other sensory modalities and can be used as means to create expectations toward food or beverage products presented concurrently with such cues. However, to date, there has been limited research on how these hand-feel touch cues could impact oral irritation elicited by capsaicin-containing products. Because oral irritation sensation is a dynamic perception lasting a period of time, temporal methodologies, such as Time-Intensity (TI) and Temporal-Check-All-That-Apply (TCATA), must be used when evaluating capsaicin-containing products. The use of temporal methodologies when examining the cross-modal effects of other cues on capsaicin irritation …

Enhancing Amino Acid Utilization For Broiler Chickens Under Different Scenarios Of Dietary Protein Reduction And Subclinical Coccidiosis, Derrell Trevor Lee

Graduate Theses and Dissertations

Five experiments were conducted to evaluate responses of broiler chickens fed diets with different dietary amino acid (AA) levels when fed normal and reduced dietary crude protein (RCP) diets and reared under different coccidiosis control programs. In the studies with the use of RCP diets, the relationship between dietary Gly + Ser and the Met:Cys ratio was investigated. Experiment 1 evaluated broilers in 2 coccidiosis control programs (live vaccine or in-feed zoalene) and fed increased dietary AA derived from soybean meal or unbound sources from 0-40 d. Vaccination impaired young (0-26 d) broiler body weight gain (BWG) and feed conversion …

Minimizing Lapses For Weight Control: The Effects Of Cue Exposure And Response Prevention Combined With Distress Tolerance, Meredith Ayers Holland

Dissertations

The current study sought to replicate and extend research into cue exposure and response prevention. Extensions included the addition of a distress tolerance psychoeducation component, delivery of the intervention using videoconferencing technology, and having male and female participants. Daily self-report data was collected using a signal contingent ecological momentary assessment procedure, wherein participants responded to scheduled text messages that went out four times a day. During each exposure session participants responded to questions related to how strong their desire to eat the food was, to their conditioned stimulus-unconditioned stimulus expectancies (CS-US expectancies), and how able they were to tolerate their …

A Word From The Writing Team (December 2022), Pam Walter, Mfa, Liz Declan, Ma, Mfa

A Word From the Writing Team (Newsletter)

This issue includes:

• Writing Retreat—Happening This Week!
• BioRender Webinar—Next Week
• Coming in 2023

Predicting Alzheimer's Disease Using Filter Feature Selection Method, Shaymaa Taha Ahmed, Suhad Malallah

Iraqi Journal of Computers, Communications, Control and Systems Engineering

lzheimer’s disease (AD) is caused by multiple variables. Alzheimer's disease development and progression are influenced by genetic variants. The molecular pathways causing Alzheimer's disease are still poorly understood. In Alzheimer's disease research, determining an effective and reliable diagnosis remains a major difficulty, particularly in the early stages (i.e., Moderate Cognitive Impairment (MCI)). Researchers and technologists working in the fields of machine learning and data mining can help improve the situation, early AD diagnosis but face a hurdle when it comes to highdimensional data processing. By reducing irrelevant and redundant data from microarray gene expression data, the technique of feature selection …

Systematic Review On Cyber-Security Applications, Shaymaa Mahmood Naser, Yossra Ali

Iraqi Journal of Computers, Communications, Control and Systems Engineering

Cybersecurity systems have been taken into account in modern information systems and methods. This is due to the increase in electronic attacks on storage information in terms of transmission, reception and storage. Therefore, the need to produce such systems in a complete way to prevent their penetration into the network has increased. In addition, artificial intelligence (AI) methods are used in cybersecurity systems as classifiers, attack detectors, and components for predicting threats that surround the network. This requires more information about threats and vulnerabilities to be covered to avoid any errors. In this paper, a systematic review is conducted to …

A Survey Of Power Consumption Minimization In Wsn Using Feedback Control Strategies, Najat M. Ramadhan, Ali M., Safanah M. Raafat

Iraqi Journal of Computers, Communications, Control and Systems Engineering

Wireless Sensor Network (WSN) represents a key network in the present and future Internet of Things (IoT) technology. WSN has an uncountable number of applications and is commonly used to aggregate information and control the physical environment remotely through small embedded devices known as wireless sensor nodes. Power consumption is one of the main challenges in WSN due to the limitation of power resources. Consequently, several techniques have been followed to optimize power consumption. The feedback control system is one of the routes that has been utilized to minimize power consumption in WSN using the mathematical model of power and …

A Proposed Authentication Method For Document In Blockchain Based E-Government System, Zainab A. Kamal, Rana F.

Iraqi Journal of Computers, Communications, Control and Systems Engineering

the primary concerns with manual transactions include corruption, lack of transparency, fraud, and mismanagement of distribution operations, all of which are created by traditional centralized applications, necessitating the migration to blockchain technology. In this work, a system is presented to secure and monitor correspondence between several nodes and store it in a decentralized database in order to secure distributed ledger transactions and safeguard against fraud and tampering when transactions are shared by multiple parties. The hashing that blockchain technology delivers in each transaction ensures a high level of security. The hashing associated with each transaction confirms all sending and receiving …

Machine Learning Approach Based On Automated Classification For Leg Rehabilitation, Ayat Naji Hussain, Sahar Adil, Basim Abdul Baki Jumma, Mohammed Najm Abdullah

Iraqi Journal of Computers, Communications, Control and Systems Engineering

Human gait data follows distinct and identifiable patterns that are critical for movement analysis and evaluation Like other biological signals. The success of a rehabilitation program is dependent on the execution of proper progress monitoring. To ensure success, diagnosis of gait anomalies, as well as the implementation of therapy to address them, must be validated in a constant and timely manner in developing youngsters. In this paper, machine learning techniques were utilized to classify foot diseases and the purpose is to increase the accuracy of disease detection and diagnosis because intelligent systems can contribute significantly in the medical field and …

Cardiovascular Patients Monitoring Using Internet Of Things And Decision Tree, Rasha Ismail Ahmed1, Rasha Mohammed, Rana Fareed Ghani

Iraqi Journal of Computers, Communications, Control and Systems Engineering

The rapid growth of the human population and the spread of many bad habits affect the health of human beings, this leads to many health problems, such as heart disease, blood pressure, and diabetes. Some of these diseases require earlier detection and fast treatment, to avoid major risks, such as permanent damage or even life loss. The fast eVolution of communications and nanotechnology nowadays is being facilitated to help with saving lives before great damage happens. This paper suggests a special architecture through which to monitor patients remotely using an Internet of Things (IoT)architecture for the purpose of notifying the …

The Field-Building And Grantee Experimentation Role Of Foundations In Impact Investing As Illustrated By A Gender-Lens Investing Case Example, Courtney Bolinson, Laura Allan

The Foundation Review

This article argues for foundations to play two critical roles in the impact investing ecosystem: to commission and/or support research that helps build more equitable and socially just impact investing and to fund grantee-specific experimentation in areas of impact investing and social enterprise that are nascent or developing.

To illustrate what this can look like, this article presents action research conducted on gender-lens investing, describing in detail a 2019 Mastercard Foundation grant to Engineers Without Borders Canada. The project involved two main goals: testing and developing gender-lens investing tools and processes with seed-stage investees during pre- or post-investment phases and …