Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medicine and Health Sciences (23772)
- Social and Behavioral Sciences (13356)
- Education (8684)
- Life Sciences (7421)
- Medical Specialties (6950)
-
- Law (6281)
- Arts and Humanities (5108)
- Public Health (4418)
- Physical Sciences and Mathematics (4286)
- Medical Sciences (3929)
- Psychology (3179)
- Business (2868)
- Higher Education (2786)
- Engineering (2627)
- Nursing (2477)
- Sociology (2215)
- Diseases (1985)
- Public Affairs, Public Policy and Public Administration (1741)
- Oncology (1535)
- Medical Education (1475)
- Environmental Sciences (1432)
- Sports Sciences (1337)
- Communication (1248)
- Mental and Social Health (1245)
- Health and Physical Education (1224)
- History (1202)
- Rehabilitation and Therapy (1178)
- Bioinformatics (1165)
- Biomedical Informatics (1114)
- Biology (995)
- Institution
-
- The Texas Medical Center Library (3382)
- Washington University School of Medicine (1713)
- Walden University (1361)
- University of Nebraska - Lincoln (1330)
- Chulalongkorn University (1187)
-
- University of Colorado Law School (986)
- Thomas Jefferson University (932)
- Western Michigan University (912)
- University of Montana (903)
- University of Florida Levin College of Law (839)
- University of Mississippi (825)
- Liberty University (800)
- Utah State University (794)
- University of New Hampshire (791)
- University of South Carolina (783)
- University of Plymouth (776)
- University of Kentucky (771)
- University of Alabama at Birmingham (763)
- Georgia Southern University (753)
- City University of New York (CUNY) (751)
- University of Central Florida (713)
- Edith Cowan University (711)
- Universitas Indonesia (708)
- San Jose State University (694)
- University of Memphis (692)
- Aga Khan University (649)
- University of Arkansas, Fayetteville (631)
- Western Kentucky University (629)
- Louisiana State University (620)
- Nova Southeastern University (620)
- Keyword
-
- Humans (3416)
- COVID-19 (2834)
- Animals (944)
- Female (890)
- Mice (668)
-
- Education (641)
- Mental health (629)
- Male (607)
- ICTS (Institute of Clinical and Translational Sciences) (530)
- Michigan (506)
- Adult (485)
- Pandemic (483)
- Child (433)
- Depression (417)
- United States (400)
- SARS-CoV-2 (399)
- Anxiety (327)
- Retrospective Studies (325)
- Children (320)
- Health (320)
- Obesity (319)
- Gender (306)
- Leadership (301)
- Physical activity (298)
- Release (297)
- Stress (294)
- Higher education (292)
- Covid-19 (290)
- Adolescent (289)
- Students (286)
- Publication
-
- Faculty, Staff and Student Publications (2045)
- Theses and Dissertations (1575)
- 2020-Current year OA Pubs (1435)
- Walden Dissertations and Doctoral Studies (1274)
- Session Laws 2001-Present (914)
-
- Faculty Publications (876)
- Dissertations (851)
- Chulalongkorn University Theses and Dissertations (Chula ETD) (836)
- Faculty, Staff and Students Publications (784)
- Electronic Theses and Dissertations (726)
- University of Montana Course Syllabi, 2021-2025 (590)
- Research outputs 2022 to 2026 (579)
- Baltic Journal of Health and Physical Activity (573)
- Florida Law Review (567)
- Doctoral Dissertations and Projects (526)
- Faculty Scholarship (481)
- Honors Theses (461)
- International Journal of Exercise Science: Conference Proceedings (417)
- Articles (393)
- Browse All News (380)
- Silver Bow Creek/Butte Area Superfund Site (333)
- Library Philosophy and Practice (e-journal) (330)
- Theses (306)
- Florida Historical Quarterly (300)
- USF Tampa Graduate Theses and Dissertations (278)
- Open Access Publications (270)
- Turkish Journal of Medical Sciences (244)
- Patient Education Projects (243)
- Publications and Research (243)
- Master's Theses (232)
- Publication Type
Articles 4771 - 4800 of 76539
Full-Text Articles in Entire DC Network
Interventions And Policy Approaches To Promote Equity In Breastfeeding, M. Vilar-Compte, R. Pérez-Escamilla, A. L. Ruano
Interventions And Policy Approaches To Promote Equity In Breastfeeding, M. Vilar-Compte, R. Pérez-Escamilla, A. L. Ruano
Department of Public Health Scholarship and Creative Works
No abstract provided.
Effect Of Umbilical Cord Essential And Toxic Elements, Thyroid Levels, And Vitamin D On Childhood Development, Jesse Cottrell, Chelsea Nelson, Catherine Waldron, Mackenzie Bergeron, Abigail Samson, Monica Valentovic
Effect Of Umbilical Cord Essential And Toxic Elements, Thyroid Levels, And Vitamin D On Childhood Development, Jesse Cottrell, Chelsea Nelson, Catherine Waldron, Mackenzie Bergeron, Abigail Samson, Monica Valentovic
Biomedical Sciences
Introduction: The in-utero environment has dramatic effects on childhood development. We hypothesized prenatal levels of inorganic agents, thyroid levels, and Vitamin D effect childhood development.
Methods: Umbilical cord blood was collected from April 3, 2013 to January 30, 2014 and analyzed for 20 different elements, thyroid and Vitamin D. A retrospective review (n = 60) was performed of well-child examinations from birth to 5 years old (y.o.).
Results: There were associations with calcium and 4 month BMI (p = <0.01), 12 month language (p = 0.03); Magnesium and 6 month language (p = 0.04) and gross motor skills at 5 years old (y.o.) (p = 0.03); Copper and 12 month fine motor (p = 0.02); Zinc with fine motor (p = <0.01) and language (p = 0.03) at 2 y.o.; Manganese was associated with language development at 2 y.o. (p = 0.02); Molybdenum and fine motor at 12 months of age (p = 0.02); Selenium with gross motor (p = 0.04) and BMI (p = 0.02) at 5 y.o.; Lead with cognitive function at 4 months (p = 0.04) and 2 y.o. (p = 0.01); Mercury with gross motor at 4 months (p = 0.04) and language at 2 y.o. (p = 0.02). Platinum at 12 months of age (p = <.01) as well as multiple associations at 5 y.o. (p = <.01). Thyroid function tests for free T3 were associated with multiple cognitive and physical milestones. T3 Uptake was associated with 5 y.o. gross motor skills (p = 0.02). Total and Free T4 was associated with cognitive development (p = <.01) and fine motor development, respectively. Vitamin D was associated with a delay of fine motor development (p<0.01).
Conclusion: There were multiple associations between umbilical cord essential and toxic elements, thyroid levels, and Vitamin D on childhood development.
Keynote Address: Alaska Native Peoples And The Environment, Elizabeth Saagulik Hensley, Esq.
Keynote Address: Alaska Native Peoples And The Environment, Elizabeth Saagulik Hensley, Esq.
Alaska Law Review
No abstract provided.
Heat Waves And A Public-Private Partnership In Alaska, Karen Sandrik, Sarah Matsumoto
Heat Waves And A Public-Private Partnership In Alaska, Karen Sandrik, Sarah Matsumoto
Alaska Law Review
The recently-passed Inflation Reduction Act represents the largest single step that Congress has taken to combat harms from climate change. In its over $360 billion commitment, the Act incentivizes clean energy development and generation, includes methods to directly lower residential utility bills and increase home efficiency, promotes cleaner transportation and agricultural practices, and funds states' and cities' efforts to meet their individual climate goals. While many environmental organizations applauded the Act's passage, some—even simultaneously—expressed concern about its tradeoffs: the Act continues to invest in fossil fuels, subsidizing pipeline construction and guaranteeing new oil and gas leases, specifically expanding leasing in …
Coastal Marine Debris In Alaska: Problems Withplastics, Pollution, & Policy, Savannah Artusi
Coastal Marine Debris In Alaska: Problems Withplastics, Pollution, & Policy, Savannah Artusi
Alaska Law Review
Plastics pollute people and the planet throughout their lifecycle, from intensive extraction of raw materials to chemical leaching during their use to entangling animals in discarded plastic products. Plastic waste is especially troublesome in Alaska, where the state's extensive shoreline and coastal communities are disproportionately inundated with plastic marine debris. Current policies internationally, in the United States, and in Alaska have not done enough to prevent plastic waste from ending up on Alaska's coasts, to hold plastic producers accountable for that waste, or to provide Alaskan communities the support needed to remove the waste themselves. This Note offers several proposals …
The Kenai Rule In Four Acts: Bear Baiting, Firearms, And Hunting: Comment & Analysis Of Alaska V. Bernhardt, Jon C. Nachtigal, Mike Stocz
The Kenai Rule In Four Acts: Bear Baiting, Firearms, And Hunting: Comment & Analysis Of Alaska V. Bernhardt, Jon C. Nachtigal, Mike Stocz
Alaska Law Review
The Kenai Rule, enacted by the U.S. Fish and Wildlife Service in 2016, prohibits (a) the hunting of brown bears with bait in the Kenai National Wildlife Refuge, (b) most hunting in the Skilak Wildlife Recreation Area, and (c) the discharge of firearms along the Kenai and Russian Rivers. The Kenai Rule was challenged by the State of Alaska and Safari Club International in Alaska v. Bernhardt. This Comment provides an overview of the case as it was heard in the District Court of Alaska. This discussion includes arguments and counterarguments surrounding the application of four legislative acts: the …
Improving Parental Education, Daisy Martinez Ortiz
Improving Parental Education, Daisy Martinez Ortiz
Capstone Projects and Master's Theses
Monterey County has one of the highest records of child maltreatment that leads to life-long consequences. COVID-19 has significantly impacted the way parent education classes are being delivered. Without the proper parental education, child maltreatment increases. Parental stress has also greatly contributed. All the stress brought among parents also posed as a factor for increased violence and child abuse. Low levels of parental education results in poor parenting. Poor parenting greatly affects a child’s social, emotional, and intellectual development. Community Human Services is a nonprofit organization dedicated to addressing a variety of issues. Among their different departments, under their mental …
Improving Collegiate Athletes’ Recognition Of Mental Wellness And Coping Strategies, Jazmin Mora
Improving Collegiate Athletes’ Recognition Of Mental Wellness And Coping Strategies, Jazmin Mora
Capstone Projects and Master's Theses
Research shows that the mental health crisis among collegiate athletes' has become an increasingly alarming issue. However, there is little done regarding the advocation for athletes on college campuses across the nation. At the junior college level, this reigns to be true, as research conducted shows there to be little research available on this group. This paper introduces a workshop that emphasizes the awareness of mental wellness and coping strategies for junior college (JUCO) athletes. The main goal of this workshop was to create a conversation about mental wellness at the JUCO level, as a majority of research was done …
Voltage-Gated Potassium Channel Dependent Mechanisms Of Cardiovascular Adaptation To Chronic Exercise., Sean Raph
Electronic Theses and Dissertations
Exercise increases cardiac workload, escalating the demand for oxygen. The myocardial vasculature responds to the greater demand for oxygen by increasing blood flow to match the needs of the heart during augmented work. Increasing blood flow requires the coronary arteries dilate (a.k.a. vasodilation); this is mediated predominantly by vascular smooth muscle cell relaxation. Vasodilation is driven through inhibition of calcium influx into vascular smooth muscle cells. The prevention of calcium influx is largely mediated by efflux of potassium via potassium channels causing membrane hyperpolarization, which in turn closes voltage-dependent (or gated) calcium channels (VDCC). Changes in vascular smooth muscle cell …
The Graduate Record Examination And Graduate Admissions: Issues In Diversity, Lauren Rankin
The Graduate Record Examination And Graduate Admissions: Issues In Diversity, Lauren Rankin
Dissertations
Doctoral education is an expensive and difficult endeavor. Program faculty are interested in finding students who will be successful in completing their courses and obtaining employment. The Graduate Record Examination (GRE) is often used to assess a student’s readiness for the rigors of graduate education. A student’s readiness for doctoral education can be assessed through analyzing the predictive validity of the GRE with various outcomes such as grade point average, scholarly output, and time to completion. However, this measure may not predict success for all students with potential bias towards students who are international and linguistically diverse. A total of …
Exploring Clinical Supervisors’ Experiences With Indirect Exposure To Trauma, Maya Kirsten Schmidt
Exploring Clinical Supervisors’ Experiences With Indirect Exposure To Trauma, Maya Kirsten Schmidt
Dissertations
In the United States, community-based victim services agencies commonly offer therapy services to survivors of interpersonal violence (Globokar et al., 2019; James & Eyjolfson, 2020; Langton, 2011). For mental health counselors and therapists working in victim services agencies and/or with survivors of interpersonal violence, indirect trauma is a known risk (Baird & Jenkins, 2003; Dworkin et al., 2016; Globokar et al., 2019; Kulkarni et al., 2013; McCann & Pearlman, 1990; Pearlman & Saakvitne, 1995; Sommer & Cox, 2005). Consequently, clinical supervisors of clinicians working with survivors of interpersonal violence must be prepared and able to effectively support clinicians in managing …
The Effect Of Hurricane Harvey On The Continuity Of Patient Care For Long-Term Care Patients Diagnosed With Dementia In Dallas And Harris Counties, Texas, Martin Mufich
Dissertations
The purpose of this study was to analyze adverse health outcomes resulting from a disruption caused by Hurricane Harvey in the continuity of patient care for two geographically distinct patient populations: long-term care patients diagnosed with dementia in Dallas County, Texas and Harris County, Texas. Review of the literature revealed three themes: patient transitions from one level of care to another, members of the healthcare team (healthcare professionals, caregivers), and policies and strategies. The research design was a retrospective, quantitative, comparative, quasi-experimental design. The population of study consisted of long- term care patients diagnosed with dementia, N = 5,539. The …
Law Enforcement Efficacy In Domestic Violence Calls Based On The Responding Officer’S Experience, Training, And Scholarly Level, Idilio Moncivais Pinedo
Law Enforcement Efficacy In Domestic Violence Calls Based On The Responding Officer’S Experience, Training, And Scholarly Level, Idilio Moncivais Pinedo
Dissertations
The purpose of this study was to provide insights into whether law enforcement officers (LEO) have been able to produce positive outcomes based on their responses when the victims have called 911. Law enforcement officers in this sample were grouped into three clusters based on the number of years of patrol experience (10 years or less versus more than 10 years), the education level (less than a bachelor’s degree versus at least a bachelor’s degree), and training (advanced training versus basic training). The key findings were A) The three clusters of law enforcement officers were well distinguished. The first cluster …
Mindfulness, Self-Compassion, Gratitude, And Burnout: A Structural Equation Model, Allegra Rose Lyon
Mindfulness, Self-Compassion, Gratitude, And Burnout: A Structural Equation Model, Allegra Rose Lyon
Dissertations
The present cross-sectional study examined the interrelationships between mindfulness, self-compassion, gratitude, and burnout in a sample of Health Service Psychology doctoral trainees (n=234) using structural equation modeling. Results suggested that mindfulness, self-compassion, and gratitude may each function as important internal resources in mitigating burnout in HSP trainees. A priori models showed poor structural fit and were respecified according to modification indices. The respecified primary model was retained as it showed a good fit (χ2(df) = 347.497(99), p < .001; RMSEA = .074; CFI = .939; TLI = .914; SRMR = .054) and significantly better fit than the respecified alternative model (Δ χ 2(1) = 7.37, p < .01). Mindfulness showed direct positive effects on self-compassion (.643) and gratitude (.346), and direct negative effects on burnout (-.344). Self-compassion (-.271) and gratitude (-.220) each also showed direct negative effects on burnout. Mindfulness also showed significant specific indirect effects on burnout via self-compassion (-.174) and gratitude (-.076). Total indirect effects of mindfulness on burnout were medium negative effects (-.250). Total effect of mindfulness on burnout was a large negative effect (-.595). These results can be used to inform changes at the organizational level for doctoral training programs and can be used at an individual level as tools for empowering trainees to increase internal resources that may help them to engage in more sustainable practice. Theoretical, research, and practice implications for counseling psychologists and limitations are discussed.
Factors Influencing Political Self-Efficacy And Political Astuteness In Undergraduate Nurse Educators, Mark William Longshore
Factors Influencing Political Self-Efficacy And Political Astuteness In Undergraduate Nurse Educators, Mark William Longshore
Dissertations
The profession of nursing, 3.9 million strong, continues to lag in taking an active role in the development of health policy. Reasons for that include lack of time, a lack of knowledge, and perceived competence of political action. The factors of knowledge and the related perceived competence, or in the case of this study, self-efficacy, could be improved through education. To that end, it was important to identify if nurse educators had the political astuteness, or knowledge, and self-efficacy. If not, how would nurses learn the necessary skills and gain confidence to be more active politically? The purpose of this …
Person-Oriented And Variable-Oriented Statistical Approaches To Understanding At-Risk, Online High School Students: Predictions Of Academic Outcomes And The Moderating Role Of Protective Factors, Amanda Renee Atwater Jacobs
Person-Oriented And Variable-Oriented Statistical Approaches To Understanding At-Risk, Online High School Students: Predictions Of Academic Outcomes And The Moderating Role Of Protective Factors, Amanda Renee Atwater Jacobs
Dissertations
Many students come to school with risk factors that negatively impact their educational attainment and overall well-being. These risk factors may include but are not limited to abuse, poverty, teen pregnancy, low academic achievement, and learning disabilities. Other types of factors have been shown to provide a protective aspect against risk, and examples include social emotional skills such as grit, flexibility, and social-awareness. There is benefit in individualizing educational experiences for at-risk adolescents based on their specific risks and available protective factors, but knowing how these factors influence and interact with one another to predict academic outcomes is the first …
Mathematical Knowledge For Teaching As Decision-Making For The University Mathematician Developing Coherence In Review Of Discrete Mathematics, Julie Lang
Dissertations
Mathematicians teaching at the university level have a deep understanding and appreciation for the mathematics that they teach. However, they rarely receive much formal training in teaching. Thus, university mathematicians must rely on their mathematical understandings and personally developed ideas of teaching to guide their decision-making. Relatively little research exists on mathematicians’ teaching practices. The purpose of this study was to examine the mathematical knowledge for teaching (MKT) of a university mathematician teaching discrete mathematics and how he leveraged his knowledge to make decisions and develop coherence among mathematical ideas during a semester review. An enactivist perspective examining a mathematician’s …
Political Astuteness Of Nurse Educators, Gail Marie Hanson Brenner
Political Astuteness Of Nurse Educators, Gail Marie Hanson Brenner
Dissertations
Nurses comprise the largest segment of the healthcare workforce. Although nurses have advocated for patients since Florence Nightingale’s time, advocating for changes in health policies that affect populations on a larger scale has not changed over time (Rasheed et al., 2020). Professional nursing associations, nurse educators, and the Institute of Medicine have all identified the need to educate nurses in advocacy and health policy. With the recent revision of the American Association of Colleges of Nursing’s Essentials publication, health policy has moved from an essential to a featured concept that is found in the competencies and subcompetencies of the domains. …
Middle School Students’ Perceptions, Experiences, And Behaviors Towards Using A Virtual Reality Application To Build Molecules, Dalal Za'al Ali Alrmuny
Middle School Students’ Perceptions, Experiences, And Behaviors Towards Using A Virtual Reality Application To Build Molecules, Dalal Za'al Ali Alrmuny
Dissertations
To deliver successful integration of virtual reality (VR) technology into chemistry education, it is essential that students have clear and positive perceptions about the purpose and the value of such integration. An important part of establishing a plan for integrating virtual reality technology into chemistry education is to explore the current perceptions, experiences, and behaviors of students towards the use of VR technology to establish an initial baseline of skills and areas in need of development. The purpose of this exploratory mixed methods study was to explore the perceptions, experiences, and behaviors of 62 middle school students in the state …
Putting Policy Into Practice: The Problematisation Of Catalan Language Planning And Ideologies In Media Discourse, Farah Ali
Global Language Studies Faculty publications
The revitalization of the Catalan language has been an ongoing effort in Catalonia for decades. The language policies that have stemmed from this effort have perpetuated ideologies that promote the use and legitimization of Catalan as both an official and a vehicular language. While this effort is widely regarded as an example of successful language revitalization, the process has not been without conflict between Spanish and Catalan, particularly in terms of domains of use and disparate attitudes towards the two languages (Newman & Trenchs-Parera, 2015; Woolard, 2016; Soler & Gallego-Balsà, 2019; Ianos et al., 2020). Given that these policies aim …
Estimating The Distribution Of Ratio Of Paired Event Times In Phase Ii Oncology Trials, Li Chen, Mark Burkard, Jianrong Wu, Jill M. Kolesar, Chi Wang
Estimating The Distribution Of Ratio Of Paired Event Times In Phase Ii Oncology Trials, Li Chen, Mark Burkard, Jianrong Wu, Jill M. Kolesar, Chi Wang
Markey Cancer Center Faculty Publications
With the rapid development of new anti-cancer agents which are cytostatic, new endpoints are needed to better measure treatment efficacy in phase II trials. For this purpose, Von Hoff (1998) proposed the growth modulation index (GMI), that is, the ratio between times to progression or progression-free survival times in two successive treatment lines. An essential task in studies using GMI as an endpoint is to estimate the distribution of GMI. Traditional methods for survival data have been used for estimating the GMI distribution because censoring is common for GMI data. However, we point out that the independent censoring assumption required …
The Distribution And Reproductive Success Of The Western Snowy Plover Along The Oregon Coast - 2022, David J. Lauten, Kathleen A. Castelein, Daniel Farrar, Mary Lee, Eleanor P. Gaines
The Distribution And Reproductive Success Of The Western Snowy Plover Along The Oregon Coast - 2022, David J. Lauten, Kathleen A. Castelein, Daniel Farrar, Mary Lee, Eleanor P. Gaines
Institute for Natural Resources Publications
We monitored the distribution, abundance and productivity of the federally threatened Western Snowy Plover (Charadrius nivosus nivosus) along the central and south coast of Oregon from 1 April – 15 September 2022. We surveyed and monitored plover activity in a project area that included, from north to south, Sutton Beach, Siltcoos River estuary, the Dunes Overlook, North Tahkenitch Creek, Tenmile Creek, Coos Bay North Spit, Bandon Snowy Plover Management Area, New River Habitat Restoration Area (HRA) and adjacent lands, and Floras Lake. Our objectives for the project area in 2022 were to: 1) estimate the size of the adult Snowy …
From The Editors, Robert Dinerstein, Jeremy R. Paul, Sonia E. Rolland, Ezra Rosser
From The Editors, Robert Dinerstein, Jeremy R. Paul, Sonia E. Rolland, Ezra Rosser
Journal of Legal Education
No abstract provided.
The Rehabilitation Of Fulton Bag & Cotton Mills: A Case For A Unique Public-History Site And Open-Air Museum, Nina Elsas
The Rehabilitation Of Fulton Bag & Cotton Mills: A Case For A Unique Public-History Site And Open-Air Museum, Nina Elsas
Master of Arts in Art and Design Theses
By the 1990s, Atlanta's historic Fulton Bag & Cotton Mills (The Mill) had fallen into extreme disrepair. After operations ceased, the 19th-century factory suffered from years of neglect, forcing the decision to either demolish or rehabilitate its industrial structures. Fortunately, a choice was made to convert the majority of Fulton Bag & Cotton Mills’ buildings into residential lofts, despite the significant financial risk. The research related to this study aims to address whether the successfully renovated Fulton Bag & Cotton Mills could identify as an open-air museum.
Answers to this question were obtained from Primary Sources (such as interviews and …
Immersive Virtual Reality As An Effective Alternative To Traditional Clinical Nursing Education: An Integrative Review, Alisha Gelder, Myrtha Labastille-Normil
Immersive Virtual Reality As An Effective Alternative To Traditional Clinical Nursing Education: An Integrative Review, Alisha Gelder, Myrtha Labastille-Normil
Master of Science in Nursing Final Projects
Immersive Virtual Reality as an Effective Alternative to Traditional Clinical Nursing Education: An Integrative Review
Abstract
Aim: To assess the usefulness of immersive virtual reality as an effective alternative to traditional face-to-face clinical education for undergraduate nursing students.
Background: The Covid-19 pandemic impacted nursing education to a point where change is needed in traditional curricula to meet program outcomes. Virtual Reality (VR) based simulations introduce students to clinical situations in a safe environment and therefore became an effective solution during the pandemic to enhance student learning. Due to the lack of research, regulatory bodies are hesitant to accept VR clinical …
The Uncertainty And Psychological Health Of Family Caregivers Of Patients With Delirium In Intensive Care Units, Amal Shokri Haji Assa
The Uncertainty And Psychological Health Of Family Caregivers Of Patients With Delirium In Intensive Care Units, Amal Shokri Haji Assa
Theses and Dissertations (ETD)
Each year, more than 5 million patients are admitted to an intensive care unit (ICU) in the United States, and up to 80 % of these patients develop delirium. Delirium is a common indicator of acute brain dysfunction in the ICU and a predictor of mortality, longer ICU/hospital stay, and long-term cognitive impairment. Family caregivers are a valuable resource in preventing, detecting, and managing delirium in the ICU. However, witnessing delirium episodes can generate adverse psychological symptoms in family caregivers that may compromise their health and well-being. Research in this area has demonstrated a gap in the literature regarding how …
A Cloning-Free Recyclable System For Crispr-Cas9 Mediated Mutant And Reversion Construction In Candida Albicans Clinical Isolates, Amanda K. Vogel
A Cloning-Free Recyclable System For Crispr-Cas9 Mediated Mutant And Reversion Construction In Candida Albicans Clinical Isolates, Amanda K. Vogel
Theses and Dissertations (ETD)
Candida albicans is a ubiquitous opportunistic fungal pathogen and one of the most prevalent causes of fungal diseases worldwide. The reference isolate SC5314 is one of the most widely used strains for both experimental and genetic studies, but it is becoming increasingly evident that genetic diversity in clinical isolates plays an important role in antifungal resistance, virulence, and pathogenicity. These recent discoveries highlight the need for genetic tools that are capable of investigating genes in multiple strain backgrounds. Here we build on the SAT1-flipper method and combine it with CRISPR-Cas9 technology to achieve cloning-free homozygous deletion in a single transformation …
Methods Development In Inflammatory Bowel Disease, Andrew B. Steimke
Methods Development In Inflammatory Bowel Disease, Andrew B. Steimke
Theses and Dissertations (ETD)
Inflammatory bowel disease (IBD) is a disease that is classified into two subtypes: ulcerative colitis (UC) and Crohn’s disease (CD). Symptoms can range from mild discomfort to requiring surgical intervention and affects approximately 1-in-200 adults in America alone, with global incidence rates increasing. While many treatments exist for IBD, perhaps the main reason for the lack of a cure is that there are many different pathogeneses that all lead to a very similar expression of symptoms. Over 240 IBD loci have been identified to date, yet the causative allele that drives the association has only been identified in ~60 of …
Potential Fitness Trade-Offs Of Elevated Esterase Activity Associated With Insecticide Resistance In The Mosquito Culex Quinquefasciatus, Timothy Schulte
Potential Fitness Trade-Offs Of Elevated Esterase Activity Associated With Insecticide Resistance In The Mosquito Culex Quinquefasciatus, Timothy Schulte
Electronic Theses, Projects, and Dissertations
One of the current major issues in the control of vector-borne disease is resistance to insecticides. Resistance to one or more insecticides has appeared in over 580 different arthropod species. Widespread resistance has led to the field of Insecticide Resistance Management (IRM). The goal of IRM is to develop insecticide-use strategies that prevent or slow down the evolution of resistance. Computer models have shown that more effective IRM strategies rely on the assumption that resistance carries a fitness cost in the absence of insecticide use.
In the mosquito Culex quinquefasciatus resistance to certain organophosphate insecticides is caused by an increased …
Backyard Orange Groves: Archaeology And Oral History Of An Ethnic Mexican Community In Downtown Redlands, Marlen Hinojosa
Backyard Orange Groves: Archaeology And Oral History Of An Ethnic Mexican Community In Downtown Redlands, Marlen Hinojosa
Electronic Theses, Projects, and Dissertations
Seeking a better life, generations of Mexican immigrant families established a thriving community in the landscape surrounded by citrus orchards flanking a stretch of Atchison, Topeka, and Santa Fe railroad tracks in Redlands, CA. As a series of revitalization projects and developments, Statistical Research Inc. (SRI) conducted archival research from the Smiley library, ethnographic and archaeological investigations to understand better the history of this unstudied ethnic Mexican barrio community near downtown Redlands. The data acquired from the oral history interviews conducted with individuals who lived or had family living in the area provided a more explicit depiction of the artifacts …