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Exploring The Use Of Piox System For Treatment Of Endocrine Disrupting Compounds, Alexander Pearson

Civil Engineering Theses

In this thesis, the Photon Initiated Oxidation (PIOx) system was investigated for its possible use in the treatment of Endocrine Disrupting Compounds (EDCs). It was theorized that the unique design of the system, namely the multiple wavelengths of UV light and the micronfoam would improve removal rates of the test contaminant when compared to other systems. 17β-estradiol was chosen as the test contaminant due to the compounds known sensitivity to ozone exposure. Two methods of testing were used, the first to test an idealized homogenous concentration (method one) and the second to mimic the sudden influx of contaminant that would …

Wearable Sensors For Plants, Nafize Ishtiaque Hossain

Electrical Engineering Theses

This thesis reports PlantFit: a research and development project that is intended to develop wearable sensors for plants. Plants are responsible for providing food, fiber, fuel, and fodder to the society. To overcome the problem of a limited land base, a more efficient farming approach needs to be developed, and thus precision farming is required. Precision farming would entail personalized healthcare in plants. When the plant is under any stress, the productivity declines. Plants release phytohormones, also known as early responders, in response to these stressors. The key crop phytohormones that respond to environmental stresses include salicylic acid (SA), indole-3-acetic …

Rna Editing Of Microtubule-Associated Protein Tau Circular Rnas Promotes Their Translation And Tau Tangle Formation, Justin Ralph Welden, Giorgi Margvelani, Karol Andrea Arizaca Maquera, Bhavani Gudlavalleti, Sandra C. Miranda Sardón, Alexandre Rosa Campos, Noémie Robil, Daniel C. Lee, Alvaro G. Hernandez, Wang-Xia Wang, Jing Di, Pierre De La Grange, Peter T. Nelson, Stefan Stamm

Sanders-Brown Center on Aging Faculty Publications

Aggregation of the microtubule-associated protein tau characterizes tauopathies, including Alzheimer’s disease and frontotemporal lobar degeneration (FTLD-Tau). Gene expression regulation of tau is complex and incompletely understood. Here we report that the human tau gene (MAPT) generates two circular RNAs (circRNAs) through backsplicing of exon 12 to either exon 7 (12→7 circRNA) or exon 10 (12→10 circRNA). Both circRNAs lack stop codons. The 12→7 circRNA contains one start codon and is translated in a rolling circle, generating a protein consisting of multimers of the microtubule-binding repeats R1–R4. For the 12→10 circRNA, a start codon can be introduced by two …

Nucleic Acid Extraction Of Human Immunodeficiency Virus From Municipal Wastewater, Fritz Vanderford, Hayley Baker, Ching-Lan Chang

Undergraduate Research Symposium Lightning Talks

In 2021, globally there were ~ 38.4 million people living with Human immunodeficiency virus (HIV), ~650,000 people died from acquired immunodeficiency syndrome (AIDS) related illnesses, ~1.5 million people acquired HIV. In the US, ~1.9 million people had HIV at the end of 2019, ~30,635 people were diagnosed with HIV in 2020.

The Fiscal Impact Of Marsy's Law: A Financial Analysis Of Victims' Rights Policy In Nevada, Elia Del Carmen Solano-Patricio

Undergraduate Research Symposium Lightning Talks

Since 2008, the "Marsy's Law" campaign has sought to embed in state constitutions a specific and lengthy set of victims' rights. In 2018, voters ratified "Question 1" in Nevada which broaded the definition of the term victim to any person directly and 'proximately' harmed by a criminal offense. As a result, Marsy's Law opens the door to the interpretation of the word "crime" and the word "victim."

Antibiotic Production Of Facultative Anaerobic Bacteria From Soil Isolates, Cierra Paaaina-Daquioag, Debra Kerr

Undergraduate Research Symposium Posters

In nature, antibiotics are produced by organisms to deter and possibly communicate with other organisms. The use of antibiotics to treat infections revolutionized medicine, but bacteria and fungal pathogens become resistant due to the overuse of these medications. A potential solution is to search for novel antibiotics produced by soil bacteria. Bacteria gene expression patterns, including antibiotic production, are different under aerobic and anaerobic conditions. The objective of this research project was to identify soil bacteria that produce antibiotics that inhibit the growth of benign relatives of the ESKAPE pathogens under aerobic and anaerobic conditions. A secondary objective was to …

Groundwater Remediation Using Modified Biochar, Kers Ung-Watson, Ismail Abdulraheem, Nikki Tibayan, Suraj Pochampally

Undergraduate Research Symposium Posters

Biochar, a lightweight black residue made of carbon, has proved to be an effective adsorbent to remove TCE from groundwater. Not only is it an economical substitute for conventional adsorbents but it can be created by using a variety of organic materials. For this project, it will rely on walnut shell feedstock to create biochar as this had the best ability to adsorb TCE.

Unpacking Athletics: An Exploration Of Identity Development For Division I Women College Athletes, Kathleen E. Scanlon

Dissertations - ALL

This dissertation explored how former Division I National Collegiate Athletic Association (NCAA) women athletes made meaning of their undergraduate experience and how it influenced their post-graduate lives. The study research questions focused on three areas: a) how participants constructed meaning from their athletic experiences and what role those experiences had in shaping their identity; b) how the participants made sense of the various systems they experienced and what bearing various identities had on their meaning making; and c) what concrete knowledge, skills and qualities participants felt they possessed today that they attribute to their intercollegiate athletic experiences.

Three semi-structured interviews …

Investigation Of Heavy Metals Removal From Aqueous Solutions By Ceramic Filters, Gehan Mostafa Kotb Tolba, Ali Gad, Abdallah Mohammed, Ahmed Farghaly Farghaly

Mansoura Engineering Journal

The study utilized the membrane filtration technique to remove two common heavy metals from aqueous solutions; the first was Pb+2, and the second was Cd+2. Manufacturing of ceramic filters was carried out through the dimensions of 20 by 20 cm and thickness of 4 cm from local clay and sawdust at different percentages of sawdust: 1.0%, 2.5%, and 4.0%. The study examined the key factors affecting the removal efficiency of the ceramic filters, such as the initial pH value (5.5 and 7.0) and initial concentration (5.0 and 10.0 mg/L) of heavy metals at a constant pressure head of 30 cm. …

Epigenetic Basis Of Diabetic Vasculopathy, Theja Bhamidipati, Manishekhar Kumar, Sumit S. Verma, Sedat Kacar, Diamond Reese, Michelle M. Martinez, Malgorzata M. Kamocka, Kenneth W. Dunn, Chandan K. Sen, Kanhaiya Singh

Einstein Health Papers

Type 2 diabetes mellitus (T2DM) causes peripheral vascular disease because of which several blood-borne factors, including vital nutrients fail to reach the affected tissue. Tissue epigenome is sensitive to chronic hyperglycemia and is known to cause pathogenesis of micro- and macrovascular complications. These vascular complications of T2DM may perpetuate the onset of organ dysfunction. The burden of diabetes is primarily because of a wide range of complications of which nonhealing diabetic ulcers represent a major component. Thus, it is imperative that current research help recognize more effective methods for the diagnosis and management of early vascular injuries. This review addresses …

Hydraulic Redistribution Under Saline Conditions, Josh Gottlieb

Civil and Environmental Engineering Undergraduate Honors Theses

Water scarcity and soil salinity are dual stressors for plants in arid, salt-affected ecosystems. Hydraulic redistribution, a hydraulic adaptation which moves water through plant roots into dry or saline soil regions along potential gradients, aids plant survival in stressful environments. Recent theory regarding hydraulic redistribution proposes limitations on the process within saline soils. This study applies a minimalist resistor-capacitor model of the soil-plant-atmosphere system to the experimental conditions of a 2010 study investigating hydraulic redistribution in a salt affected area. The effectiveness of the model is evaluated, and a sensitivity analysis is conducted to identify key dynamics affecting the moisture …

The Dark Side Of Due Process: Part Iii, How To Use Irreverent Double-Talk To Speak Back To Bad Men, Joshua J. Schroeder

St. Mary's Law Journal

Most American lawyers take for granted that the common law established almost all the ordinary causes of action we know today. As Joseph Story’s Commentaries acknowledged, the common law is the basis of the entire U.S. system of law. Common law struggled with feudal and canon forms and eventually transformed them for the benefit of ordinary people even in the face of the most heinous travesties of the English and American past.

The Witch Judges of Salem, Massachusetts and the Parliament of Saints in England did not prevail through despotic radicalism to demolish the common law through codification. Legal positivism …

Covid-19 And Cancelled 2020 College Football Games Contracts: Force Majeure?, Drew Thornley

St. Mary's Law Journal

After COVID-19, majeure clauses accounting for the possibility of a pandemic will become the norm in college football game contracts. Indeed, some contracts are already including pandemics in their lists of force majeure-triggering events. Such language has already been added to collegiate game contracts. For example, a contract signed in May 2020 for the 2025 football game between Wisconsin and Miami (Ohio) lists as force majeure-triggering events “regional or global epidemics, pandemics, quarantines, and other similar health threats (e.g.[,] coronavirus, influenza, etc.).” Scholars explain that “the onset of the novel coronavirus pandemic warranted immediate revisitation of college football contracts.”

However, …

From Patients To Patents: The Disappearing I Of Innovation, Maggi Robert

St. Mary's Law Journal

The creation of the Mayo/Alice two-step test for patent eligible subject matter flipped the patent world upside down. Following its establishment, invalidation rates soared—particularly in the healthcare sector—impacting patients everywhere. The importance of patents in healthcare innovation and innovation generally has been emphasized as the consequences of this framework are realized.

The United States is no longer seen as a clear leader in innovation, and as a result, the economy is at risk. Start-ups and investors have turned to foreign nations where return on their investments in innovation are protected. This level of uncertainty regarding patents has never been seen …

Developing An Early Life Cycle Manufacturability Assessment For Conceptual Designs, Tonya Gamblin Mccall

Theses and Dissertations

Studies have shown that 70 – 80% of a product's life cycle costs are committed by the end of the product design phase (Anderson, 2014; National Research Council, 1991; Swift, 1987). This supports the general claim that decision making in the conceptual stage drives the cost throughout the life cycle. The use of concurrent engineering has been viewed as the answer to this problem, offering the Design for Excellence (DFX) as one approach for evaluating product designs across specific disciplines. This research focuses on a subset of DFX referred to as Design for Manufacturability to develop a means to assess …

Hdl Cholesterol: Too Much Of A Good Thing? Cardiovascular, Elizabeth A. Moxley

Faculty Articles, Papers, and Other Scholarship

It is considered a well-established fact that high-density lipoprotein cholesterol (HDL-C) is a robust, inverse predictor of the risk of experiencing an atherosclerotic cardiovascular (ASCVD) event.[i] Whereas, low HDL-C characterizes an atherogenic dyslipidemia that reflects adverse lifestyle choices, impaired metabolism, and increased cardiovascular risk.[ii]

From B2b Survivor To Sap’S Swallow: Sap Ariba’S Success, John Wang, Steve Bin Zhou, Yang Li, Houda El Bouhissi

Department of Information Management and Business Analytics Faculty Scholarship and Creative Works

Ariba Inc. and Commerce One Inc. (C1), two bellwethers with e-entrepreneurship in the e-commerce field, provided business-to-business (B2B) spend management and supply chain services. After having been wiped out by the devaluation of the stock market that followed the dot-com era, C1 is extinct today. Having faced the same market condition and serious competition, innovative Ariba had a different path and was acquired by SAP in 2012. Nowadays, SAP Ariba (formerly known as Ariba) is the largest digital B2B network on the planet. Why did Ariba survive whereas C1 collapsed? The authors explore the external (hidden costs, high-priced software, hurtful …

Pharmacotherapy For Opioid Use Disorder In Mississippi, Amanda Michelle Whitacre

Doctoral Projects

The opioid epidemic is affecting Mississippi’s young to middle-aged adult population in a profound way. Pharmacotherapy for opioid use disorder (OUD) is the gold standard treatment. Despite the FDA-approved evidence-based treatment of pharmacotherapy for OUD, rural areas often lack providers available who will initiate and provide maintenance of this life-saving medication. For this doctoral project, a 36-question survey was developed based on a preliminary literature review. The survey was disseminated to advanced practice registered nurses (APRNs) in the family and psychiatric specialties across Mississippi to assess the barriers to APRNs filling the gap in pharmacotherapy prescribing for OUD. A continuing …

Effects Of A Behavioral Intervention On Physical Activity, Diet, And Health-Related Quality Of Life In Pregnant Women With Elevated Weight: Results Of The Hipp Randomized Controlled Trial, Sarah Wilcox Phd, Jihong Liu, Gabrielle Turner-Mcgrievy Ph.D., Rd, Alycia K. Boutte, Ellen Wingard Msph, Rd, Ld

Faculty Publications

Background

Physical activity (PA), diet, and health-related quality of life (HRQOL) are related to maternal and infant health, but interventions to improve these outcomes are needed in diverse pregnant women with elevated weight.

Methods

Health In Pregnancy and Postpartum (HIPP) was a randomized controlled trial. Women who were pregnant (N=219, 44% African American, 56% white) with overweight or obesity but otherwise healthy were randomized to a behavioral intervention grounded in Social Cognitive Theory (n=112) or to standard care (n=107). The intervention group received an in-depth counseling session, a private Facebook group, and 10 content-based …

Exploring The Acute Cardiovascular Effects Of Floatation-Rest., M C Flux, Thomas H. Fine, Tate Poplin, Obada Al Zoubi, William A. Schoenhals, Jesse Schettler, Hazem H. Refai, Jessyca Naegele, Colleen Wohlrab, Hung-Wen Yeh, Christopher A. Lowry, Jason C. Levine, Ryan Smith, Sahib S. Khalsa, Justin S. Feinstein

Manuscripts, Articles, Book Chapters and Other Papers

The central nervous system (CNS) exerts a strong regulatory influence over the cardiovascular system in response to environmental demands. Floatation-REST (Reduced Environmental Stimulation Therapy) is an intervention that minimizes stimulation from the environment, yet little is known about the autonomic consequences of reducing external sensory input to the CNS. We recently found that Floatation-REST induces a strong anxiolytic effect in anxious patients while paradoxically enhancing their interoceptive awareness for cardiorespiratory sensations. To further investigate the physiologic nature of this anxiolytic effect, the present study measured acute cardiovascular changes during Floatation-REST using wireless and waterproof equipment that allowed for concurrent measurement …

Goal Attainment After Treatment With Abobotulinumtoxina And A Tailored Home Therapy Programme In Children With Upper Limb Spasticity: Descriptive, Exploratory Analysis Of A Large Randomized, Controlled Studya, Jorge Carranza-Del Río, Nigar Dursun, Cigdem Cekmece, Marcin Bonikowski, Weronika Pyrzanowska, Edward Dabrowski, Ann Tilton, Joyce Oleszek, Magali Volteau, Simon Page, Angela Shierk, Mauricio R. Delgado

School of Medicine Faculty Publications

OBJECTIVE: This exploratory analysis of a large, randomized, double-blind study (NCT02106351) describes the effect of treatment with abobotulinumtoxinA followed by a tailored home exercises therapy programme in enabling children with upper limb spasticity due to cerebral palsy to achieve their functional goals using goal attainment scaling (GAS). METHODS: Children with cerebral palsy and spasticity in ≥ 1 upper limb received up to 4 injection cycles of abobotulinumtoxinA (2 U/kg (cycle 1 only), 8U/kg and 16U/kg) into the elbow and wrist flexors and other upper limb muscles selected to support individual treatment goals. Children followed a home exercises therapy programme, which …

Author Of Books On Racial Reconciliation, Social Justice To Speak At Mlk Breakfast, University Of Dayton

News Releases

The Very Reverend Canon Kelly Brown Douglas, dean of the Episcopal Divinity School at Union Theological Seminary, canon theologian at Washington National Cathedral, and author of two books on racial reconciliation and social justice, will be the speaker at the University's annual Rev. Martin Luther King Jr. Prayer Breakfast.

Determinism V. Free Will & Genetic Evidence Of Addiction In Plea Bargaining And Sentence Mitigation: Conversion Of Incarceration To Probation And Rehabilitation Based On Genetic Addiction Risk Severity (Gars) Test, Kenneth Blum, Paul Mullen, Richard Green

St. Mary's Law Journal

In this Article, Dr. Kenneth Blum and his team present the case of a presently abstinent, thirty-five year old alcoholic (“AG”) who has several convictions for DWI. AG has undergone and continues to be engaged in out-patient substance abuse treatment. He entered treatment before adjudication and was mandated by the court to continue treatment to assist in maintaining sobriety. Treatment included the administration of the Genetic Addiction Risk Severity (“GARS”) Test.

AG was facing a probable five-year sentence for his fifth DWI conviction in Bexar County, Texas. However, because AG’s genetic risk results indicated a genetically induced dopamine dysfunction, hypodopaminergia, …

The Demographic And Socioeconomic Patterns Of New Latino Immigrants In New York City In The 2010s, Qiyao Pan

Center for Latin American, Caribbean, and Latino Studies

Introduction: This report examines the demographic and socioeconomic patterns of new immigrants that arrived between 2010 and 2019 in New York City. It focuses on the characteristics and shifting dynamics of these newcomers in three time periods: 2010-2012, 2013-2015, and 2016-2019.

Methods: This report uses the American Community Survey PUMS (Public Use Microdata Series) data for all years released by the Census Bureau and reorganized for public use by the Minnesota Population Center, University of Minnesota, IPUMSusa, (https://usa.ipums.org/usa/index.shtml). See Public Use Microdata Series Steven Ruggles, J. Trent Alexander, Katie Genadek, Ronald Goeken, Matthew B. Schroeder, and Matthew Sobek. Integrated Public …

Fall/Winter 2022: Former Un High Commissioner Speaks At Snc, St. Norbert College

St. Norbert College Magazine 2019-2023

Former U.N. High Commissioner for Human Rights Zeid Ra’ad al-Hussein spoke at St. Norbert College about global and U.S. human rights challenges, emphasizing historical context, the importance of moral education, and the power of dissent and combating xenophobia.

Telehealth Acceptance Among Appalachian Respondents During Covid 19: A Secondary Data Analysis, Victoria Hood-Wells, Florence M. Weierbach, Amy Wahlquist, Janet M. Keener, Manik Ahuja, Hadii M. Mamudu

ETSU Faculty Works

Purpose: The purpose of this study is to examine the relationship between telehealth use, telehealth satisfaction, and chronic medical conditions among residents living in Appalachian and non-Appalachian communities.

Sample: A COVID-19 public health survey was distributed via social media and healthcare clinics in the tri-state region of central Appalachia. Survey responses were limited to adults aged ≥18 years who consented to participate in the survey that self-identified as an individual with one or more chronic medical conditions (n=195).

Method: Simple descriptive statistics including frequencies, percentages, means, and standard deviations (SDs) were calculated for variables of interest both overall and by …

The Diamond, December 9, 2022, Dordt University

Dordt Diamond

• Front Page: Paperwork Delays Cause Problems for International Students; Airband Rocks the BJ Haan; Campus Christmas Events
• News: Peepholes; Dordt's Fall Semester Ends Later Than Previous Years; Dordt Gaming Guild Tabletop War Game Event
• Feature: "Glitch" in Ticketmaster May be its End Game; Iowa Removes Praxis Requirement for Teaching Licensure; FIFA World Cup Held During Classes for the First Time; Terracotta Films; Julie Van Otterloo Returns as a Second-Year Teacher; Small Groups Watch The Chosen
• Opinion: A Perspective on Christian Education as a Requirement; Questioning the Purpose of CORE 140 and 145; What To Do Over …

Moral Status And The Oversight Of Research Involving Chimeric Animals, Patricia Marshall, Kaitlynn P. Craig

Faculty Scholarship

The use of nonhuman animals in research has long been a source of bioethical and scientific debate. We consider the oversight and use of nonhuman animals in chimeric research. We conducted interviews with twelve members of embryonic stem cell research oversight committees, nine members of institutional animal care and use committees, and fourteen scientists involved in human–nonhuman-animal chimeric research in different areas of the United States. Interviews addressed animal welfare and conceptual issues associated with moral status and humanization of nonhuman animals that contain human cells. Our findings suggest that concepts of enhanced moral status and consciousness are not very …

Principles For Using Remote Data Collection Devices And Deep Learning In Evaluating Social Impact Indicators Of Engineered Products For Global Development, Bryan J. Stringham

Theses and Dissertations

Evaluating the social impacts of engineered products, or effects products have on the daily lives of individuals, is critical to ensuring that products are having positive impacts while avoiding negative impacts and to learning how to improve product designs for a more positive social impact. One approach to quantifying a product's social impact is to use social impact indicators that combine user data in a meaningful way to give insight into the current social condition of an individual or population. However, determining social impact indicators relative to engineered products and individuals in developing countries can be difficult when there is …

A Text-Based Smoking Cessation Intervention For Sexual And Gender Minority Groups: Protocol For A Feasibility Trial, Irene Tami-Maury, Rebecca Klaff, Allison Hussin, Nathan Grant Smith, Shine Chang, Lorna Mcneill, Lorraine R Reitzel, Sanjay Shete, Lorien C Abroms

Faculty, Staff and Student Publications

BACKGROUND: Smoking among sexual and gender minority (SGM) groups, which include lesbian, gay, bisexual, transgender, and queer individuals, has been reported to be highly prevalent. This is attributed to several factors, including minority-specific stress and targeted tobacco marketing. Therefore, this population is at an increased risk for tobacco-related diseases. SMS text messaging programs have been found to be effective for smoking cessation and appeal to traditionally hard-to-reach populations over other interventions. It has also been suggested that targeted and tailored interventions could be more effective among SGM smokers because they can be designed to assure a safe, validating health care …