Digital Commons Network^™

Defective Proteostasis In Induced Pluripotent Stem Cell Models Of Frontotemporal Lobar Degeneration, Sidhartha Mahali, Rita Martinez, Melvin King, Anthony Verbeck, Oscar Harari, Bruno A Benitez, Kanta Horie, Chihiro Sato, Sally Temple, Celeste M Karch

2020-Current year OA Pubs

Impaired proteostasis is associated with normal aging and is accelerated in neurodegeneration. This impairment may lead to the accumulation of protein, which can be toxic to cells and tissue. In a subset of frontotemporal lobar degeneration with tau pathology (FTLD-tau) cases, pathogenic mutations in the microtubule-associated protein tau (MAPT) gene are sufficient to cause tau accumulation and neurodegeneration. However, the pathogenic events triggered by the expression of the mutant tau protein remain poorly understood. Here, we show that molecular networks associated with lysosomal biogenesis and autophagic function are disrupted in brains from FTLD-tau patients carrying a MAPT p.R406W mutation. We …

Saving Indian Consumers From Unfair Contract Terms – The Impact Of Section 2(46), Consumer Protection Act, 2019 On The Home Buyers Industry, Shivkrit Rai

International Journal on Consumer Law and Practice

On July 24, 2020, the Central Government notified the Consumer Protection Act, 2019, thereby replacing the Consumer Protection Act, 1986. One of the most significant changes brought about in the new Act is the introduction of a provision dealing with the unfair contract. This article traces how judicial and quasi-judicial forums dealt with unfair clauses in contracts prior to the implementation of the Consumer Protection Act, 2019. This is done by discussing different nuances from Competition Commission, and Consumer Commission along with narratives from United Kingdom’s Consumer Rights Act, 2015. The author argues that an explicit provision empowering the Consumer …

Role Of Irdai In Promoting E-Commerce In Insurance Sector While Ensuring Policyholder Protection., Goda Mallikarjun Dr

International Journal on Consumer Law and Practice

Insurance is a financial service for protecting life, health, and property from risk. Insurance Regulatory and Development Authority of India was brought in to protect policyholders’ interests and regulate, promote and develop the insurance market in an orderly manner after liberalization and allowing private particiaption and foreign equity in the insurance sector. The increasing useof the internet and mobile for providing banking and financial sevices generated demand for similar channels of electronic access and commerce in insurance also. IRDAI issued the Guidelines for e-Commerce mandating that the same should be carried out only through the Insurance Self-Network Platform to be …

Product Liability Action: A Tooth To Strengthen Consumer Protection, Ashok R. Patil Prof. (Dr.)

International Journal on Consumer Law and Practice

As the world shifts to technological advancements, the advent of e-commerce marks its peak, particularly in India, where it has been earmarked as the fastest growing market with an annual growth rate of 51%. While these developments are an important part of globalization, a few challenges come along. Issues like unfair contracts, privacy, data protection, faulty goods, refund or return remained unaddressed as the earlier existing Consumer Protection Act, 1986 did not elucidate on the same. Given the above, the Law Commission of India had recommended that a separate law be enacted for better consumer protection. Based on the recommendations …

An Exigency For Consumer Protection Against Counterfeit Product Marketing On The Internet: A Legislative Perspective, Deepti Nahush Khubalkar Dr, Shilpa Santosh Sharma Dr

International Journal on Consumer Law and Practice

The world of the Internet has opened a limitless market for sellers and buyers but at the same time, it has opened a new chapter of infringement and theft of the identity of well-established companies which trade online. Both original and fake companies are attracted by the lucrative market online; this has ultimately resulted in trading in counterfeit products. Digital marketing is more than just thebusiness of disseminating product information for online sales. It involves content building for marketing, designing of the website, information about the product, customer support tools, chat rooms, online payment system etc. Marketing is a commercial …

Age-Old Tools And Techniques To Protect Consumers Need To Be Sharpened In The Light Of Artificial Intelligence, Rajesh Bahuguna Prof, Radhey Shyam Jha Dr

International Journal on Consumer Law and Practice

We all are consumers by birth and remain consumers till death, and at the same time, it is also true that a consumer becomes the victim of exploitation in different ways. Adulterations, underweight, duplicate or cloned goods, and misleading and insufficient information are some ways of victimizing consumers. Today, we are standing at a juncture where we have a series of legislative, judicial, and administrative efforts to protect consumers. On the other hand, we have a plethora of incidents of exploitation of consumers. The nature of the legislation available for the protection of consumers is not purely criminal but sometimes …

Legal Approaches To Liability Of Digital Platform Operators To Consumers, Dmitriy Kozhemyakin, Svetlana Mironova

International Journal on Consumer Law and Practice

This article is devoted to the consideration of approaches to the liability of digital platform operators to consumers. Given that the number of digital consumers who use goods (works, services) purchased using digital platforms is growing, it becomes necessary to define the concept and features of such platforms, determine the relationship between them, consumers and suppliers, as well as identify problems of legal liability of digital platforms. The article draws attention to the fact that despite the differences in the terminology used in legislation and literature (digital platforms, digital platform operators, aggregators, owners of aggregators, etc.), all of the above …

Faculty And Student Online Mentoring Preferences, Lee Stadtlander, Arfe Ozcan, Latoya Johnson, Briana Nicholson, Narjis Hyder

Journal of Educational Research and Practice

Isolation of online doctoral students intensifies when they transition from coursework to the dissertation/capstone phase, limiting them to interacting with their mentors. A three-round modified Delphi study was conducted to examine mentoring preferences of online doctoral students and faculty. The first round provided qualitative data regarding the preferred mentoring practices for faculty and alumni. Round 1 qualitative data were organized into Likert questions and used in the second round, which resulted in data about frequency of mentoring practices for the same participants from Round 1. The third round provided data about importance of each preference rated by faculty and current …

Listen Up!: Measuring And Mitigating College Students’ Most Commonly-Reported Listening Challenges, Karla Hunter, Erin Lionberger, Ashley Phillips, Kaitlyn Luebbert, Andrea N. Briggs

Discourse: The Journal of the SCASD

This study updates the existing literature on listening education in two ways: 1) by providing an assessment of an effective listening education intervention and 2) by identifying what college students' self-assessment and reflection revealed as their most common barriers to listening and the actions that helped mitigate those challenges. Through content analysis, five graduate student coders analyzed six consecutive pre-Covid-19 semesters of student submissions to a Listening Log Self-Assessment assignment in an online interpersonal communication course (n = 186). This experiential activity was designed to motivate students' metacognitions to elicit accurate self-appraisals based on reflections of students' current listening encounters …

Front Matter

Discourse: The Journal of the SCASD

No abstract provided.

Information Needs And Seeking Behaviour Of Road Transport Employee Association Of Nigeria (Rtean) Members, Yenagoa Branch, Bayelsa State, Nigeria, Abraham Tabor Etebu Ph.D, Cln, Mnla, Godwin Oberhiri-Orumah (Cln, Mnla)

Library Philosophy and Practice (e-journal)

The study sought to identify the information needs and information-seeking behaviour of Road Transport Employee Association of Nigeria (RTEAN) Members in Yenagoa Branch, Bayelsa State. The specific purpose of the study was to: examine the information needs of Road Transport Employee Association of Nigeria members in Yenagoa, Bayelsa State, Nigeria; find out how Road Transport Employee Association of Nigeria members in Yenagoa, Bayelsa State, Nigeria seek for needed information; determine the problems encountered by Road Transport Employee Association of Nigeria members in Yenagoa, Bayelsa State, Nigeria while seeking for needed information; and proffer solutions to the determined problems of information …

Prevent Violence, Strengthen Democracy: Electoral Codes Of Conduct For The United States, Cathy Buerger, Tonei Glavinic

Peace and Conflict Studies

As the events of 2020 and January 2021 demonstrated, the United States is not immune from election-related violence, yet efforts to reduce such violence are typically only used in the international development context rather than domestically. One strategy the U.S. advocates for in fledgling democracies is electoral codes of conduct – agreements in which politicians and parties agree to refrain from certain types of harmful speech and behavior, such as targeted harassment of marginalized groups, disinformation, and incitement to violence. In this paper, the authors analyze electoral codes of conduct around the world that restrict political speech in various contexts, …

Palestinian-Arabs Volunteering In State Institutions In Israel: Reconciliation And Peacebuilding Or Conflict And Suspicion?, Edith Blit Cohen, Mays Essa

Peace and Conflict Studies

Volunteering in government institutions by national minorities in conflict with the state raises fascinating issues. The identity of Palestinian-Arabs in Israel is divided, as they belong to the Palestinian people and Arab nation, as well as nominal citizens of Israel. This perception study explores the meaning of the volunteering experience for fifteen Palestinian-Arabs in various Israeli state institutions. Three themes arise from the interview analysis: motives for volunteering, challenges faced by the volunteers, and their coping strategies. The study contributes to the theory and practice of the meaning of volunteering in government institutions for minority members in conflict with the …

How Can You Call Her A Woman? Male Soldiers’ Views On Women In The Drc Armed Forces, Dostin Lakika, Ingrid Palmary

Peace and Conflict Studies

There has been a longstanding body of literature on women in the armed forces at least since the 1970s (Segal, 1999). This literature varies considerably in its approach, from feminist work that reflects on the forms of masculinity produced through military and militarization, to work that considers women’s role in the army and attitudes towards women in the army. Furthermore, policy efforts to increase women’s participation in the army (such as UN Security Council Resolution 1325) have explicitly called for the inclusion of women in peace and security efforts. In this paper, we contribute to this literature by assessing how …

A Case Of Inferior Dislocation Of Right Shoulder, Gauri A. Nair

Digital Journal of Clinical Medicine

Dislocation of the shoulder is the commonest of all large joint dislocations. Inferior dislocation of the shoulder, also called luxatio erecta, is a rare form. It appears in less than 0.5% of all shoulder dislocations. Patient characteristically presents with an arm locked in upright position - Luxatio erecta. Its etiology, clinical presentation and radiographic findings are distinct. An awareness of associated potential neurovascular injuries and rotator cuff tears is important in this rare entity and should be excluded with high index of suspicion. Preferred modality of treatment depends upon the age of the patient and the extent of neurovascular involvement. …

Depression Secondary To Isotretinoin – A Case Report, Rohan Karkra, Megha Sadashiv, Kishor M

Digital Journal of Clinical Medicine

Depression is one of the leading causes of morbidity in the world and significantly affects the lives of people suffering from it. The exact cause of depression has not been established and it is believed to be a complex play between various social, biological, environmental, personal factors. A relatively rare but distinct cause includes pharmacological agents.

In this case report, we describe the case of a 17-year-old girl who developed depression with psychotic symptoms on two occasions, both preceded by a history of Isotretinoin use. She was admitted and treated with anti-psychotics and psychotherapy with significant improvement in her mental …

Personality Disorder Predisposing To Alcohol Dependence, Samarchitha S Ms., Venkatesh Babu Dr., Megha Sadashiv Dr., Sudeep Pk Mr.

Digital Journal of Clinical Medicine

No abstract provided.

High-Velocity Fracture: Case Of Displaced Intertrochanteric Fracture Offemur With Spiral Fracture Of Shaft Of Right Femur, Gayathri Sureshkumar Nair

Digital Journal of Clinical Medicine

BACKGROUND

Intertrochanteric fracture is a common orthopedic condition characterized by extracapsular fractures of the proximal femur that occur between the greater and lesser trochanter with predominance in elderly population, especially those with osteoporosis, wherein even a low energy mechanism is enough to cause the fracture.

There is an observed female predominance with ratio between 2:1 and 8:1. [1,2]

Commonly observed symptoms include shortened and externally rotated limb, pain and bony tenderness around the hip joint, inability to bear weight on the affected limb to name a few.

Management depends upon age of patient, nature of the fracture, number of comminuted …

A Rare Case Of Extra-Ventricular Supra-Sellar Neurocytoma – A Diagnostic Conundrum, Rohan Karkra, Suchitha Satish, Peri Keerthi

Digital Journal of Clinical Medicine

The brain and its associated structures are often the primary source or site of metastases for many tumors. Neurocytoma is a relatively rare neuronal neoplasm, first described as an intra-ventricular tumor that is not known to be very aggressive. It constitutes less than 0.5% of CNS neoplasms. Extraventricular Neurocytoma (EVN) is an extremely rare variant, of which only 12 cases have ever been reported in the supra-sellar region. In all of these 12 cases, the patient was initially misdiagnosed; hence, this condition is a diagnostic conundrum. Grossly, the tumor is firm and smooth with extensive blood supply and fibrous tissue. …

Comparison Of Conventional Pap Smear And Manual Liquid Based Cytology With P16 Marker In Screening For Cervical Cancer In Indian Tertiary Healthcare Setups In Mysuru, Gayathri Sureshkumar Nair, Nandini Manoli, Nandish Manoli

Digital Journal of Clinical Medicine

In India, there are 20.2 per 100000 new cases of Cervical Cancer diagnosed and 11.1 per 100000 deaths annually accounting for more than one fifths of global cervical cancer deaths. [1] Thus, due to an absence of a national immunization program to cover human papillomavirus (HPV) vaccination and lack of accessible cervical cancer screening, the disease is characterized by late detection, lack of access to affordable and quality health care, and high mortality rates. [2]

Papanicolaou Smear Test was a novel invention by Dr George Papanicolaou in the year 1927 which gained maximum popularity in 1950 as a screening test …

Physical Therapy Students’ Perception Of Their Ability Of Clinical And Clinical Decision-Making Skills Enhanced After Simulation-Based Learning Courses In The United States: A Repeated Measures Design, Fatima Bizama, Masoor Alameri, Kristy Demers, Derrick F. Campbell

Education Collection

Purpose It aimed to investigate physical therapy students’ perception of their ability of clinical and clinical decision-making skills after a simulation-based learning course in the United States.

Methods Survey questionnaires were administered to voluntary participants, including 44 second and third-year physical therapy students of the University of St. Augustine for Health Sciences during 2021–2022. Thirty-six questionnaire items consisted of 4 demographic items, 1 general evaluation, 21 test items for clinical decision-making skills, and 4 clinical skill items. Descriptive and inferential statistics evaluated differences in students’ perception of their ability in clinical decision-making and clinical skills, pre- and post-simulation, and post-first …

The Fierce Green Fire: Vol. 13 Issue 10, Wofford College. Department Of Environmental Studies

The Fierce Green Fire

No abstract provided.

The Ongoing Search For Democracy: A Comparative Analysis Of Racial Equality In Cuba And The United States, Michael T. Siderio Jr.

Honors Student Research

This Capstone Project is structured as a comparative analysis of the fight for racial equality for Afro-Cubans in Cuba and how it compares to racial equality for African Americans in the United States, specifically focusing on contemporary issues relating to employment and economic opportunities, as well as police brutality. Historical background will be given on each topic within the scope of racial equality, and a comparative analysis on how they are similar and how they differ will also be provided. The overarching goal of the research on historical background and doing the comparative analysis is to synthesize both respective movements …

How The Perceived Value Of Education, Parental Influences, And Students' Perceived Success Affect Post-Graduate Decisions, Valerie Blanchard

Honors Projects in Mathematics

While technical education has been enhanced in many ways over the past few decades, college is still the preferred post-graduate path for many students and is the societal norm. This study will analyze the value that students view in their career path that leads them to make their post-graduate decisions. The goal of this research is to better understand why students pursue college and how these decisions come to be with specific attention paid to the impact of gender, interests, and self-efficacy. This understanding can educate others about the gravity of social norms and can start conversations about how to …

Sr 22-23-14 Cc, Marshall University Faculty Senate

Recommendations

No abstract provided.

There's No Business Like Show Business: Analyzing The Factors Of Broadway Shows That Have The Most Influence Over The Theatre Industry's Recovery From The Covid-19 Shutdown, Megan Swenson

Honors Projects in Accounting

The COVID-19 pandemic had a significant impact on the Broadway theatre industry, with all performing arts venues suspending performances for at least 18 months. The economic recession associated with the COVID-19 pandemic left actors, directors, and theater workers unemployed for months on end, causing undue economic harm to individual finances and the industry. Since the reopening of Broadway plays and musicals in the fall of 2021, very few shows have been able to reach pre-pandemic levels of income and attendance. This project aims to use a regression analysis of weekly gross income for Broadway shows to predict what factors will …

Force Majeure Clauses At The Age Of Covid-19: How Should Courts Interpret Them And Why A Conservative Application Is Necessary, Dorothy Swagler

Global Business Law Review

A force majeure clause aims to define the scope of unforeseeable events that may excuse or delay a party’s performance. In the wake of the Coronavirus (COVID) pandemic, many parties to disputes attempted to turn to force majeure clauses written in boilerplate language. COVID is distinguishable, however, from other historical force majeure events because of its rapid global development and international economic impact brought upon by government restriction and access issues. In effect, these boilerplate clauses coupled with this novel pandemic, left parties in dispute ill-equipped to know whether their force majeure clause was enforceable. This resulted in a flood …

Towards Improving Calibration In Object Detection Under Domain Shift, Muhammad Akhtar Munir, Muhammad Haris Khan, M. Saquib Sarfraz, Mohsen Ali

Computer Vision Faculty Publications

With deep neural network based solution more readily being incorporated in real-world applications, it has been pressing requirement that predictions by such models, especially in safety-critical environments, be highly accurate and well-calibrated. Although some techniques addressing DNN calibration have been proposed, they are only limited to visual classification applications and in-domain predictions. Unfortunately, very little to no attention is paid towards addressing calibration of DNN-based visual object detectors, that occupy similar space and importance in many decision making systems as their visual classification counterparts. In this work, we study the calibration of DNN-based object detection models, particularly under domain shift. …

The Minutes Of The Marshall University Faculty Senate Meeting, October 2022, Marshall University Faculty Senate

Faculty Senate Minutes

No abstract provided.

Sizeism--What Multicultural Education & Training Are Missing, Jen Rynes

Counselor Education Capstones

Training in multiculturalism is a major focus in most counselor education graduate programs. These programs seek to graduate competent counselors who aspire to serve all populations. The harsh reality is that many programs fail to acknowledge body diversity and sizeism in these multicultural courses and trainings. There are a multitude of reasons why body diversity needs to be a part of multicultural education and training. The literature reviewed in this paper has a purpose of discussing those reasons, dismantling the many myths associated with fatness, identifying how body size intersects with other diverse identities, and reviewing current multicultural guidelines and …