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2022

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The Anxiety Of Freshmen Students In Library Use At Central Luzon State University, Philippines, Roselyn Marquez Madia, Camia Abergos Lasig Jan 2022

The Anxiety Of Freshmen Students In Library Use At Central Luzon State University, Philippines, Roselyn Marquez Madia, Camia Abergos Lasig

Library Philosophy and Practice (e-journal)

The purpose of this study was to assess the level of library anxiety among freshmen students at Central Luzon State University (CLSU) in the Philippines in order to develop an appropriate library program to help alleviate their anxieties and increase library usage, thereby contributing to student academic success. The survey questionnaire was used to gather the necessary information. It was adapted and modified from the psychometric instrument by Bostick Library Anxiety Scale (LAS) to measure the library anxiety level of 342 respondents using the systematic sampling design technique. Cronbach's alpha was calculated on the 57 statements. The test has strong …


Staff Motivation, Discipline And Performance Appraisal As Correlates Of Staff Job Performance In University Libraries In Bayelsa And Rivers States., Biokuromoye Fyneman Ph.D Jan 2022

Staff Motivation, Discipline And Performance Appraisal As Correlates Of Staff Job Performance In University Libraries In Bayelsa And Rivers States., Biokuromoye Fyneman Ph.D

Library Philosophy and Practice (e-journal)

This study examined staff motivation, discipline and performance appraisal as correlates of staff job performance in university libraries in Bayelsa and Rivers States. Three research objectives and questions were stated to guide the study. Three hypotheses were also articulated. The study adopted survey correlational research design involving a population of 356 staff in six university libraries. The entire population of 356 library staff in the six university libraries in Bayelsa and Rivers States was adopted as sample for the study. Personnel Management Rating Scale (PMRS) and Library Staff Job Performance Rating Scale (LSJPRS) were used to collect data. Mean, standard …


Understanding Covid-19 Related Health Literacy Skills And Competencies Among The Working Lis Professionals In Dr. Zakir Husain Central Library, Jamia Millia Islamia: A Study, Ms. Nisha Mn, Manir Uddin Ansari Mua Jan 2022

Understanding Covid-19 Related Health Literacy Skills And Competencies Among The Working Lis Professionals In Dr. Zakir Husain Central Library, Jamia Millia Islamia: A Study, Ms. Nisha Mn, Manir Uddin Ansari Mua

Library Philosophy and Practice (e-journal)

Health literacy has become an integral component of human life, and it plays a significant role in ensuring safety from a variety of deadly diseases. India's health literacy rate is below average when compared to other countries. Since the Covid-19 pandemic, doctors and volunteers from all over the world have been striving to promote health literacy to raise public awareness through various media. Given the foregoing, the main objective of this study is to identify the level of Covid-19 related health literacy among working LIS professionals at Jamia Millia Islamia's Dr.Zakir Husain Central Library. The survey approach is being used …


Information Seeking Behavior In Digital Environment: A Study Of Post Graduate And Phd Students Of Odisha University Of Agriculture And Technology, Bhubaneswar, Debraj Meher Dr, Mukesh Behera, Monisha Mishra Jan 2022

Information Seeking Behavior In Digital Environment: A Study Of Post Graduate And Phd Students Of Odisha University Of Agriculture And Technology, Bhubaneswar, Debraj Meher Dr, Mukesh Behera, Monisha Mishra

Library Philosophy and Practice (e-journal)

Information seeking behavior (ISB) is defined as a human habit that entails a conscious search for information in order to fill a gap. In a University, a user visits the university library first when he/she needs information. The information seeking behavior varies for different user categories. Examining the information demands and behaviors of agriculture students, particularly those at OUAT, is the main goal of this study. A well-structured questionnaire was used to collect data for this research. A total of 245 fully completed surveys, representing an 87.5 percent response rate, were returned from 380 surveys distributed to graduate (PG) and …


Crowdsourcing In Libraries In The Digital Age, Benil Joseph Jan 2022

Crowdsourcing In Libraries In The Digital Age, Benil Joseph

Library Philosophy and Practice (e-journal)

Information has been an intrinsic part of humanity throughout the years. Libraries and information centers have always been considered, as the custodians of information. However, with the overwhelming of information in the digital age, libraries find it difficult to deliver the right information at the right time. Despite various efforts by libraries to deliver information on time, at times the necessity of libraries is questioned. Crowdsourcing gains importance at this juncture. Today since catalogs and other allied information are mostly online, users can perform various activities like refining metadata of records, adding the new subject heading that library staff overlooked, …


Assessment Of Information Literacy And Fake News Identification Of Benguet State University Freshmen: Implications For Library Literacy Program, Daniel Jr Balbin Jan 2022

Assessment Of Information Literacy And Fake News Identification Of Benguet State University Freshmen: Implications For Library Literacy Program, Daniel Jr Balbin

Library Philosophy and Practice (e-journal)

The world is experiencing a rapid and massive spread of misinformation referred to as “infodemic” (WHO, 2020, cited by Salvi, et al., 2021). Despite information literacy had been a long-offered solution to information problems (Horton, 2007) and studies discovered that accurate identification of fake news was significantly associated with information literacy (Jones-Jang, et al., 2021), approaches to IL instruction must be updated and must adapt to the changing information society and environment (SCONUL, 2018; Rutledge and LeMire, 2017).

It aimed to determine the level of information literacy and fake news identification of the students. It also determined if there is …


Utilizing The Potentials Of Big Data In Library Environments In Nigerian For Recommender Services, Job Onekutu Sani, Nneka Angela Oseji Jan 2022

Utilizing The Potentials Of Big Data In Library Environments In Nigerian For Recommender Services, Job Onekutu Sani, Nneka Angela Oseji

Library Philosophy and Practice (e-journal)

The big data revolution has gained global attention and initiated creative innovations in every field and libraries as engines of access to information have also been affected by this new trend. Libraries in this part of the world have not utilized the amazing potential of big data in library services. In this time, when various terms such as algorithms age, petabytes age, data age, etc. are been used to describe the activities initiated by machine learning, industries and organizations can achieve much by incorporating inspiring and innovative tools to improve services and performance. In this vein libraries in Nigeria are …


Factors Influencing Career Choice Among Secondary School Students In Aba North Of Abia State And Implications For School Library Development, Ndubuisi Eze Chukwu, Chinenye Ifeoma Ogidi, Immaculata N. Akaneme, Leonard Chidi Ilechukwu Jan 2022

Factors Influencing Career Choice Among Secondary School Students In Aba North Of Abia State And Implications For School Library Development, Ndubuisi Eze Chukwu, Chinenye Ifeoma Ogidi, Immaculata N. Akaneme, Leonard Chidi Ilechukwu

Library Philosophy and Practice (e-journal)

The purpose of the study was to investigate factors influencing the career choice among secondary school students and implications for school library development. The study design adopted was ex-post-facto. The study was guided by four research questions and four null hypotheses. A sample of 65 students was selected using the multi-stage sampling technique. Data were collected with a self-structured questionnaire structured on a 4-point rating scale. The research questions were analyzed using mean and standard deviation. The null hypotheses were tested at 0.5 level of significance using independent t-test. The major findings showed that there is no significant difference in …


Enhancing Children's Achievement In Basic Science Using Library Electronic Books: A Case Of Simple Repeated Evaluation, Christian Ugwuanyi Phd Jan 2022

Enhancing Children's Achievement In Basic Science Using Library Electronic Books: A Case Of Simple Repeated Evaluation, Christian Ugwuanyi Phd

Library Philosophy and Practice (e-journal)

The 21st century classrooms demand a lot from both the teachers and the learners due to the technological developments and demands in teaching and learning. These days, most parents buy their children (smart/android phones, tablets, or laptops without knowing the educational benefits of these gadgets in accessing online learning materials. The 21st century technology has made the use of e-books very beneficial to the teaming population of learners who have access to the internet, but it is worrisome that there is a dearth of research on such issues in the Nigerian context. Thus, this research examined the effect …


Assessment Of Preschool Librarians’ Library Disciplining Strategies For Effective Use Of Preschool Library, Charity C. Okeke M.Ed, Clara O. Ifelunni Phd, Anthonia N. Ngwoke Phd, Gloria C. Ugwu Phd, Eucharia N. Aye Phd, Chinedu I.O. Okeke Prof, Nnamdi T. Ekeanyanwu Prof, Christian S. Ugwuanyi Phd Jan 2022

Assessment Of Preschool Librarians’ Library Disciplining Strategies For Effective Use Of Preschool Library, Charity C. Okeke M.Ed, Clara O. Ifelunni Phd, Anthonia N. Ngwoke Phd, Gloria C. Ugwu Phd, Eucharia N. Aye Phd, Chinedu I.O. Okeke Prof, Nnamdi T. Ekeanyanwu Prof, Christian S. Ugwuanyi Phd

Library Philosophy and Practice (e-journal)

Effective use of school libraries is very germane in achieving effective teaching and learning at various levels of education. Most importantly, the cultivation of the habit of using library by preschool children at the foundation phase will go a long way in patterning the reading habits of the children as they advance in their education. Currently, most preschool children exhibit unruly traits which are potential threats to effe3ctive management of preschool library. However, literature is scarce on the disciplining practices of the preschool Librarians for effective management of school library. Thus, this study was necessitated to explore the library disciplining …


Influence Of Preschool Librarians’ Demographic Characteristics On Their Library Discipline Practices: An Ex-Post Facto Research, Christian S. Ugwuanyi Phd, Charity C. Okeke M.Ed, Chinedu I.O. Okeke Prof Jan 2022

Influence Of Preschool Librarians’ Demographic Characteristics On Their Library Discipline Practices: An Ex-Post Facto Research, Christian S. Ugwuanyi Phd, Charity C. Okeke M.Ed, Chinedu I.O. Okeke Prof

Library Philosophy and Practice (e-journal)

The success of various discipline practices in controlling children's behavior in the classroom has been a major source of concern among preschool librarians. Despite the relevance of library discipline in managing disruptive conduct in children, there appears to be a knowledge gap regarding the impact of preschool librarians' demographic features on their discipline practices. As a result, this study measured the influence/impact of preschool librarians' demographic factors on their library disciplinary practices using authoritarian behavioural theory. With a sample of 156 preschool librarians in Enugu State's Nsukka Education Zone, the study used an ex-post facto research design. The researchers developed …


Design And Development Research: Prototyping In Web Opac For Indonesian Children, Rifa Nadila, Riche Cynthia Johan, Gema Rullyana Jan 2022

Design And Development Research: Prototyping In Web Opac For Indonesian Children, Rifa Nadila, Riche Cynthia Johan, Gema Rullyana

Library Philosophy and Practice (e-journal)

As a searching tool for bibliography sources in libraries, OPAC should provide convenience to meet the users’ information needs, with notes that every user has different needs and characteristics. OPAC at large libraries in Indonesia, including the National Library of Republic Indonesia, is designed without adjusting children’s ability and is mostly used for adults. The need for children’s OPAC development in Indonesia and children’s unique characteristics in searching strategies is defined as problem backgrounds. Therefore, this study aims to develop a simple search OPAC in simulated prototype form. The Design and Development method is used by adapting stages of the …


Creating Community Of Young Readers During Covid-19 Lockdown: A Comprehensive Study Of A Digital Reading Platform: Storyweaver, Shaveta Azad, Rupak Chakravarty Prof. Jan 2022

Creating Community Of Young Readers During Covid-19 Lockdown: A Comprehensive Study Of A Digital Reading Platform: Storyweaver, Shaveta Azad, Rupak Chakravarty Prof.

Library Philosophy and Practice (e-journal)

Reading stories to children when they are young is the most effective way to keep them creatively engaged. Children in multilingual countries require free access to story repositories for leisure reading. In India, a country with hundreds of mother tongues, books are largely published in English and Hindi, owing to market economics. Various studies have shown that learning and reading become more important in one's mother tongue and that when a child reads in two or more languages during early years, gains a deeper understanding of language and its effective use.

In this paper, the researchers have tried to discover; …


Pupils’ Experience With E-Learning During Covid-19 Lockdown In Delta State., Gloria Ogheneghatowho Oyovwe-Tinuoye Dr, Esharenana E. Adomi Prof Jan 2022

Pupils’ Experience With E-Learning During Covid-19 Lockdown In Delta State., Gloria Ogheneghatowho Oyovwe-Tinuoye Dr, Esharenana E. Adomi Prof

Library Philosophy and Practice (e-journal)

This study scrutinised pupils’ experience with e-learning during COVID-19 lockdown in Delta State. The study adopted a descriptive survey research design with five (5) research objectives of the study. The questionnaire was constructed after consultation of related literature to ensure that pertinent items were encompassed in it. A self-constructed questionnaire entitled “Pupils Experience with E-Learning during COVID- 19 Lockdown Questionnaire (PEELDC19LQ) was designed by the researchers. The population of the study comprised of all pupils in Delta State who participated in e-learning to meet up with the third curriculum and eventually used for promotion for the next class. The researchers …


Comparative Study For Assessment Of Koha And Slims Features In Public Sector College Libraries Of Sindh, Aijaz Akhter Ahmedani, Khurram Shahzad, Rashid Siddique, Sara Khan Jan 2022

Comparative Study For Assessment Of Koha And Slims Features In Public Sector College Libraries Of Sindh, Aijaz Akhter Ahmedani, Khurram Shahzad, Rashid Siddique, Sara Khan

Library Philosophy and Practice (e-journal)

The core aim of the study was to assess KOHA and SLiMS features in Government College Libraries of Sindh. The objectives of the study were (a) to explore the reasons of Koha and SLiMS adoption and (b) to recognize the problems face by library professionals in the implementation of Koha and SLiMS. To meet the objectives, the study used a quantitative research approach and the survey method based on the questionnaire. Purposive sampling technique was used. The data was gathered only from those librarians who were working in Govt Colleges of Karachi, Hyderabad, and Sukkur and were using Koha or …


Justification Of Manual Classification Of Information Resource In Ict Age In Nigeria, Marcus Oladotun Aragabye Jan 2022

Justification Of Manual Classification Of Information Resource In Ict Age In Nigeria, Marcus Oladotun Aragabye

Library Philosophy and Practice (e-journal)

The purpose of this study is to emphasize the reasons why manual classification of information materials should not be abandoned in current ICT era, particularly in Nigeria. Libraries are no exception to ICT applications, and we can observe how they have already altered library services and activities. Also, Information Technology (IT) has made it presence in almost every sphere of human activity including the library practice but to have fully automated classification scheme is yet to be implemented. Library operation, such as cataloging, reference service, and the rest has a feel of this. For example, ICT has incorporated copy cataloguing …


Evaluation Of The Utilization Of Electronic Filing System As Information Retrieval Medium At The Records Centre Unit Of The Ministry Of Environment And Forestry, Indonesia, Nilam Ananda Putri, Muhammad Azwar Jan 2022

Evaluation Of The Utilization Of Electronic Filing System As Information Retrieval Medium At The Records Centre Unit Of The Ministry Of Environment And Forestry, Indonesia, Nilam Ananda Putri, Muhammad Azwar

Library Philosophy and Practice (e-journal)

The Electronic Filing System is a form of concrete application of information technology in archival institutions. This system is used to facilitate and speed up the work of archivists. In practice, this system needs to be evaluated. This study aims to evaluate the utilization of the Electronic Filing System as an information retrieval information medium at the Records Center Unit of the Ministry of Environment and Forestry and to provide solutions on how to overcome various existing obstacles. This type of research is descriptive with a quantitative approach. Sampling using a non-probability technique with saturated sampling. The …


Reconstructing Neural Circuits Using Multiresolution Correlated Light And Electron Microscopy, Karl Friedrichsen, Pratyush Ramakrishna, Jen-Chun Hsiang, Katia Valkova, Daniel Kerschensteiner, Josh L Morgan Jan 2022

Reconstructing Neural Circuits Using Multiresolution Correlated Light And Electron Microscopy, Karl Friedrichsen, Pratyush Ramakrishna, Jen-Chun Hsiang, Katia Valkova, Daniel Kerschensteiner, Josh L Morgan

2020-Current year OA Pubs

Correlated light and electron microscopy (CLEM) can be used to combine functional and molecular characterizations of neurons with detailed anatomical maps of their synaptic organization. Here we describe a multiresolution approach to CLEM (mrCLEM) that efficiently targets electron microscopy (EM) imaging to optically characterized cells while maintaining optimal tissue preparation for high-throughput EM reconstruction. This approach hinges on the ease with which arrays of sections collected on a solid substrate can be repeatedly imaged at different scales using scanning electron microscopy. We match this multiresolution EM imaging with multiresolution confocal mapping of the aldehyde-fixed tissue. Features visible in lower resolution …


Socioecological Model-Based Design And Implementation Principles Of Lower Limb Preservation Programs As Partners For Limb-Loss Rehabilitation Programs- A Mini-Review, Vipul Khetarpaul, John P Kirby, Patrick Geraghty, John Felder, Prateek Grover Jan 2022

Socioecological Model-Based Design And Implementation Principles Of Lower Limb Preservation Programs As Partners For Limb-Loss Rehabilitation Programs- A Mini-Review, Vipul Khetarpaul, John P Kirby, Patrick Geraghty, John Felder, Prateek Grover

2020-Current year OA Pubs

People with lower limb loss, especially of dysvascular etiology, are at substantial risk for both ipsilateral and contralateral reamputation. Additionally, while not as well documented for reamputation, there is recognition that amputation incidence is influenced by not only sociodemographic factors such as sex, race, socioeconomic status, but also by system factors such as service access. A systems strategy to address this disparity within the field of limb-loss rehabilitation is for Limb-loss Rehabilitation Programs (LRP) to partner with medical specialists, mental health professionals, and Limb Preservation Programs (LPP) to provide comprehensive limb care. While LPPs exist around the nation, design principles …


The Relevance Of Rich Club Regions For Functional Outcome Post-Stroke Is Enhanced In Women, Anna K. Bonkhoff, Laura Heitsch, Chia-Ling Phuah, Et Al. Jan 2022

The Relevance Of Rich Club Regions For Functional Outcome Post-Stroke Is Enhanced In Women, Anna K. Bonkhoff, Laura Heitsch, Chia-Ling Phuah, Et Al.

2020-Current year OA Pubs

No abstract provided.


Clinical And Molecular Characteristics Of A Novel Rare De Novo Variant In Ppp2ca In A Patient With A Developmental Disorder, Autism, And Epilepsy, Iris Verbinnen, Sara S Procknow, Lisa Lenaerts, Sara Reynhout, Aujan Mehregan, Chris Ulens, Veerle Janssens, Katherine A King Jan 2022

Clinical And Molecular Characteristics Of A Novel Rare De Novo Variant In Ppp2ca In A Patient With A Developmental Disorder, Autism, And Epilepsy, Iris Verbinnen, Sara S Procknow, Lisa Lenaerts, Sara Reynhout, Aujan Mehregan, Chris Ulens, Veerle Janssens, Katherine A King

2020-Current year OA Pubs

PP2A-related (neuro) developmental disorders are a family of genetic diseases caused by a heterozygous alteration in one of several genes encoding a subunit of type 2A protein phosphatases. Reported affected genes, so far, are


Donor Chimerism And Immune Reconstitution Following Haploidentical Transplantation In Sickle Cell Disease, Yaya Chu, Brenda Grossman, Shalini Shenoy, Et Al Jan 2022

Donor Chimerism And Immune Reconstitution Following Haploidentical Transplantation In Sickle Cell Disease, Yaya Chu, Brenda Grossman, Shalini Shenoy, Et Al

2020-Current year OA Pubs

INTRODUCTION: We previously reported the initial results of a phase II multicenter transplant trial using haploidentical parental donors for children and aolescents with high-risk sickle cell disease achieving excellent survival with exceptionally low rates of graft-versus-host disease and resolution of sickle cell disease symptoms. To investigate human leukocyte antigen (HLA) sensitization, graft characteristics, donor chimerism, and immune reconstitution in these recipients.

METHODS: CD34 cells were enriched using the CliniMACS

RESULTS: HLA antibodies were detected in 7 of 11 (64%) evaluable patients but rarely were against donor antigens. Myeloid engraftment was rapid (100%) at a median of 9 days. At 30 …


Primates Chunk Simultaneously-Presented Memoranda, Charles D Holmes, Shinung Ching, Lawrence H Snyder Jan 2022

Primates Chunk Simultaneously-Presented Memoranda, Charles D Holmes, Shinung Ching, Lawrence H Snyder

2020-Current year OA Pubs

Though much research has characterized both the behavior and electrophysiology of spatial memory for single targets in non-human primates, we know much less about how multiple memoranda are handled. Multiple memoranda may interact in the brain, affecting the underlying representations. Mnemonic resources are famously limited, so items may compete for "space" in memory or may be encoded cooperatively or in a combined fashion. Understanding the mode of interaction will inform future neural studies. As a first step, we quantified interactions during a multi-item spatial memory task. Two monkeys were shown 1-4 target locations. After a delay, the targets reappeared with …


3d Bi-Directional Transformer U-Net For Medical Image Segmentation, Xiyao Fu, Zhexian Sun, Haoteng Tang, Eric M Zou, Heng Huang, Yong Wang, Liang Zhan Jan 2022

3d Bi-Directional Transformer U-Net For Medical Image Segmentation, Xiyao Fu, Zhexian Sun, Haoteng Tang, Eric M Zou, Heng Huang, Yong Wang, Liang Zhan

2020-Current year OA Pubs

As one of the popular deep learning methods, deep convolutional neural networks (DCNNs) have been widely adopted in segmentation tasks and have received positive feedback. However, in segmentation tasks, DCNN-based frameworks are known for their incompetence in dealing with global relations within imaging features. Although several techniques have been proposed to enhance the global reasoning of DCNN, these models are either not able to gain satisfying performances compared with traditional fully-convolutional structures or not capable of utilizing the basic advantages of CNN-based networks (namely the ability of local reasoning). In this study, compared with current attempts to combine FCNs and …


Classical And Γδ T Cells Are Each Independently Sufficient To Establish Protection Against A Classical Strain Of Klebsiella Pneumoniae, Joseph J Mackel, Catherine Morffy Smith, Rachel K Wasbotten, Joy Twentyman, David A Rosen Jan 2022

Classical And Γδ T Cells Are Each Independently Sufficient To Establish Protection Against A Classical Strain Of Klebsiella Pneumoniae, Joseph J Mackel, Catherine Morffy Smith, Rachel K Wasbotten, Joy Twentyman, David A Rosen

2020-Current year OA Pubs

Infections with classical strains of the Gram-negative bacterium


Binary Acoustic Metasurfaces For Dynamic Focusing Of Transcranial Ultrasound, Zhongtao Hu, Yaoheng Yang, Lu Xu, Yao Hao, Hong Chen Jan 2022

Binary Acoustic Metasurfaces For Dynamic Focusing Of Transcranial Ultrasound, Zhongtao Hu, Yaoheng Yang, Lu Xu, Yao Hao, Hong Chen

2020-Current year OA Pubs

Transcranial focused ultrasound (tFUS) is a promising technique for non-invasive and spatially targeted neuromodulation and treatment of brain diseases. Acoustic lenses were designed to correct the skull-induced beam aberration, but these designs could only generate static focused ultrasound beams inside the brain. Here, we designed and 3D printed binary acoustic metasurfaces (BAMs) for skull aberration correction and dynamic ultrasound beam focusing. BAMs were designed by binarizing the phase distribution at the surface of the metasurfaces. The phase distribution was calculated based on time reversal to correct the skull-induced phase aberration. The binarization enabled the ultrasound beam to be dynamically steered …


Four Decades Of Mapping And Quantifying Neuroreceptors At Work In Vivo By Positron Emission Tomography, Albert Gjedde, Dean F Wong Jan 2022

Four Decades Of Mapping And Quantifying Neuroreceptors At Work In Vivo By Positron Emission Tomography, Albert Gjedde, Dean F Wong

2020-Current year OA Pubs

Decryption of brain images is the basis for the necessary translation of the findings from imaging to information required to meet the demands of clinical intervention. Tools of brain imaging, therefore, must satisfy the conditions dictated by the needs for interpretation in terms of diagnosis and prognosis. In addition, the applications must serve as fundamental research tools that enable the understanding of new therapeutic drugs, including compounds as diverse as antipsychotics, antidepressants, anxiolytics, and drugs serving the relief of symptoms from neurochemical disorders as unrelated as multiple sclerosis, stroke, and dementia. Here we review and explain the kinetics of methods …


Survival After Simultaneous Pancreas-Kidney Transplantation In Type 1 Diabetes: The Critical Role Of Early Pancreas Allograft Function, Mengmeng Ji, Mei Wang, Wenjun Hu, Mohamed Ibrahim, Krista L. Lentine, Massini Merzkani, Haris Murad, Yazen Al-Hosni, Ronald Parsons, Jason Wellen, Su-Hsin Chang, Tarek Alhamad Jan 2022

Survival After Simultaneous Pancreas-Kidney Transplantation In Type 1 Diabetes: The Critical Role Of Early Pancreas Allograft Function, Mengmeng Ji, Mei Wang, Wenjun Hu, Mohamed Ibrahim, Krista L. Lentine, Massini Merzkani, Haris Murad, Yazen Al-Hosni, Ronald Parsons, Jason Wellen, Su-Hsin Chang, Tarek Alhamad

2020-Current year OA Pubs

Simultaneous pancreas-kidney transplantation (SPK) carries about a 7%-22% risk of technical failure, but the impact of early pancreas allograft loss on subsequent kidney graft and patient survival is not well-defined. We examined national transplant registry data for type 1 diabetic patients who received SPK between 2000 and 2021. Associations of transplant type (i.e., SPK, deceased-donor kidney transplant [DDKA], living-donor kidney transplant [LDKA]) with kidney graft failure and patient survival were estimated by multivariable inverse probability of treatment-weighted accelerated failure-time models. Compared to SPK recipients with a functioning pancreas graft 3 months posttransplant (SPK,P+), LDKA had 18% (Time Ratio [TR] 0.82, …


Enhancing Neuroimaging Genetics Through Meta-Analysis For Tourette Syndrome (Enigma-Ts): A Worldwide Platform For Collaboration, Peristera Paschou, Emily D Bihun, Tamara Hershey, Jonathan M Koller, Kevin J. Black, Et Al. Jan 2022

Enhancing Neuroimaging Genetics Through Meta-Analysis For Tourette Syndrome (Enigma-Ts): A Worldwide Platform For Collaboration, Peristera Paschou, Emily D Bihun, Tamara Hershey, Jonathan M Koller, Kevin J. Black, Et Al.

2020-Current year OA Pubs

Tourette syndrome (TS) is characterized by multiple motor and vocal tics, and high-comorbidity rates with other neuropsychiatric disorders. Obsessive compulsive disorder (OCD), attention deficit hyperactivity disorder (ADHD), autism spectrum disorders (ASDs), major depressive disorder (MDD), and anxiety disorders (AXDs) are among the most prevalent TS comorbidities. To date, studies on TS brain structure and function have been limited in size with efforts mostly fragmented. This leads to low-statistical power, discordant results due to differences in approaches, and hinders the ability to stratify patients according to clinical parameters and investigate comorbidity patterns. Here, we present the scientific premise, perspectives, and key …


Examining Virtual Driving Test Performance And Its Relationship To Individuals With Hiv-Associated Neurocognitive Disorders, David Grethlein, Vanessa Pirrone, Kathryn N Devlin, Will Dampier, Zsofia Szep, Flaura K Winston, Santiago Ontañón, Elizabeth A Walshe, Kim Malone, Shinika Tillman, Beau M Ances, Venk Kandadai, Dennis L Kolson, Brian Wigdahl Jan 2022

Examining Virtual Driving Test Performance And Its Relationship To Individuals With Hiv-Associated Neurocognitive Disorders, David Grethlein, Vanessa Pirrone, Kathryn N Devlin, Will Dampier, Zsofia Szep, Flaura K Winston, Santiago Ontañón, Elizabeth A Walshe, Kim Malone, Shinika Tillman, Beau M Ances, Venk Kandadai, Dennis L Kolson, Brian Wigdahl

2020-Current year OA Pubs

SIGNIFICANCE: Existing screening tools for HIV-associated neurocognitive disorders (HAND) are often clinically impractical for detecting milder forms of impairment. The formal diagnosis of HAND requires an assessment of both cognition and impairment in activities of daily living (ADL). To address the critical need for identifying patients who may have disability associated with HAND, we implemented a low-cost screening tool, the Virtual Driving Test (VDT) platform, in a vulnerable cohort of people with HIV (PWH). The VDT presents an opportunity to cost-effectively screen for milder forms of impairment while providing practical guidance for a cognitively demanding ADL.

OBJECTIVES: We aimed to: …