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The Role Of Rad51 In Trichomonas Vaginalis, Dominique Hall

University of the Pacific Theses and Dissertations

Drug resistance to the current treatments on the market is on the rise, therefore there is strong interest in understanding what could be causing the resistance, how resistance could be spreading through the population, and finding some possible new drug targets. One protein of interest is Radiation Sensitive Protein 51 (Rad51). It is a protein that is involved in homologous recombination as well as other processes such as DNA damage repair. While Trichomonas vaginalis traditionally has been known to replicate via binary fission, a modified form of closed mitosis, there is some evidence that meiosis, or at least some form …

Implementation And Sustainability Of Trauma-Informed Care Via Multi-Tiered System Of Support (Mtss), Aisha Larie Elloie Brice

University of the Pacific Theses and Dissertations

Trauma-informed care is a relatively new construct in K-12 education, and districts across the United States are seeking avenues to meet the needs of their students. The COVID-19 pandemic elevated the need for districts to develop appropriate supports to address student and adult trauma. Traumatic events can affect a child’s mental, physical, social-emotional, and/or spiritual well-being (Substance Abuse and Mental Health Service Administration, 2011). Furthermore, children with an elevated risk of trauma may not be able to access these supports outside of the school setting (Baweja et al., 2015). Therefore, educational systems need to develop trauma-informed care models for schools …

Motivating Factors For Academic Dishonesty And Reoccurrence Prevention Of These Behaviors, Andrew Bryzgornia

All Electronic Theses and Dissertations

Teachers often turn to assessments to measure a student’s learning in a class. The intent is for the student to complete this assessment by meeting the instructor’s requirements, but often they look for alternate means to aid in the assignment’s completion, which is known as academic dishonesty or cheating. While students may illegally use notes, partner with others, and more, it is common for the students to have other justifications beyond simply desiring a better grade in the class. Not knowing they are cheating, believing cheating is not wrong, believing the class is too difficult, distrusting the instructor, and having …

The Impact Of Classroom Management On Behavior Regulation For Students In Early Childhood And Elementary School Classrooms, Katherine S. Winters

All Electronic Theses and Dissertations

A significant obstacle for teachers in early childhood and elementary classrooms is regulating negative student behavior. The implementation of classroom management programs is a strategy used by school districts worldwide to lessen learning distractions caused by negative student behavior to improve classroom quality. This thesis is a review of studies specifically linking the impact that classroom management interventions have on behavior regulation. Review of both preventative and reactive classroom management practices were discussed as well as the training process and implementation fidelity. The consistent trend in the research related to increasing positive student behavior in the classroom, is that positive …

Successful Co-Teaching Models In The Secondary Setting, Alexandra L. Hermoza

All Electronic Theses and Dissertations

Co-teaching is an educational practice that emerged in the early 1970’s with the creation of the IDEA act. In this inclusive teaching model, a special education and a general education teacher work together to share responsibilities of the classroom such as planning lessons, monitoring student progress, and managing student behaviors and learning. While some teachers are not able to implement this strategy successfully, other teachers and schools find great success in this inclusive practice. Studies indicate that teachers struggle with co-teaching when they do not communicate adequately or are not given the proper training or time to collaborate. Teachers who …

The Influence Of Differentiation: Student Engagement, Academic Achievement, Classroom Management And Barriers To Successful Implementation, Elise E. Erlandson

All Electronic Theses and Dissertations

Differentiation is the instructional practice founded on the belief that every student deserves to receive the instruction that they need on an individual basis. When successfully implemented, it can positively influence student engagement, academic achievement, and classroom management. While each of these components of a classroom space are interconnected and interdependent, the positive influence of differentiation can be seen throughout. This may look like a higher percentage of student engagement in instruction, higher academic achievement, and more positive, collaborative classroom communities. However, there are definite barriers to a successful, effective implementation of differentiation in an individual classroom or within larger …

Race Car Aerodynamics Simulation And Transmitted Tire Reaction Forces, Mark T.J. Lin, Periklis Papadopoulos

Faculty Research, Scholarly, and Creative Activity

Often in Computational Fluid Dynamics integral forces and restoring moments are calculated, but the location where they should be applied may not always be clear. This is because the location is not intuitive: it is dependent on the vehicle’s velocity and its orientation (e.g. sideslip angle). A technique has been developed to translate the aerodynamic forces to the reaction forces on the vehicle’s tires. In this study, CFD simulation is performed with a 7.5° yaw to look at the effect of cornering. To understand aerodynamic effect on vehicle dynamics one must know the location at which this force is applied. …

Multiple Sediment Incorporation Events In A Continental Magmatic Arc: Insight From The Metasedimentary Rocks Of The Northern North Cascades, Washington (Usa), Ann E.H. Hanson, Stacia M. Gordon, Kyle T. Ashley, Robert B. Miller, Elizabeth Langdon-Lassagne

Faculty Research, Scholarly, and Creative Activity

The rheology and composition of arc crust and the overall evolution of continental magmatic arcs can be affected by sediment incorporation events. The exhumed Cretaceous–Eocene North Cascades arc exposes abundant meta­ sedimentary rocks that were incorporated into the arc during multiple events. This study uses field relationships, detrital zircon geochronology, bulk rock geo­ chemistry, geothermometry, and quartz­in­garnet geobarometry to distinguish approximate contacts and emplacement depths for different metasedimentary units to better understand their protolith incorporation history and impact on the arc. The Skagit Gneiss Complex is one of the main deep crustal units of the North Cascades arc. It includes …

Forecasting The Outcomes Of Managing A Rare Endemic Plant At Its Elevational Limit Under Climate Change Scenarios, Ethan Reibsome

Cal Poly Humboldt theses and projects

Lupinus constancei (Lassics lupine) is an exceptionally rare forb with a population that in 2020 consisted of 1,300 individuals located on two adjacent mountaintops in northwestern California, USA. Past work has demonstrated the species is threatened by high levels of seed predation by small mammals, which is likely the result of fire exclusion and the subsequent vegetation encroachment that both increases small mammal habitat and directly reduces suitable habitat for the species. Because of this, active management through caging of reproductive individuals to reduce seed consumption has been conducted every year since 2003. In addition, growing season temperatures have increased …

Does Having Siblings Affect Caretaking Responses To Infants?, Kaitlin Rose Duskin

Cal Poly Humboldt theses and projects

Infant facial cues affect a variety of caretaking-related responses in adults. These effects have primarily been explored as they relate to parental care, however infants receive care from others who are not their parents and it would be important for any caregiver, regardless of parental status, to respond to infant cues effectively. Because siblings often fulfill a caregiver role in the home, this study investigated whether having siblings, younger siblings in particular, influences the way in which adults respond to infant cues. Contrary to my predictions, the findings in this study indicate that having siblings does not influence how rewarding …

Assessing The Potential And Pathways For Renewable Energy Transformations In Orleans, California, Malcolm Prescott Moncheur De Rieudotte

Cal Poly Humboldt theses and projects

In what is now known as the state of California in the United States, the Karuk Tribe is interested in deploying a renewable-powered microgrid in the rural community of Orleans to improve electricity system reliability and resilience to address a wide range of challenges, including extreme events such as wildfires. This study assesses the potential of local distributed renewable energy and battery storage to meet Orleans' energy needs today and in the increasingly electrified future using an energy model. It also identifies existing cultural and social priorities for energy technology along with structural barriers to renewable energy adoption and the …

Johnson V. M'Intosh: Christianity, Genocide, And The Dispossession Of Indigenous Peoples, Cynthia J. Boshell

Cal Poly Humboldt theses and projects

Using hermeneutical methodology, this paper examines some of the legal fictions that form the foundation of Federal Indian Law. The text of the U.S. Supreme Court’s 1823 Johnson v. M’Intosh opinion is evaluated through the lens of the Convention on the Prevention and Punishment of the Crime of Genocide to determine the extent to which the Supreme Court incorporated genocidal principles into United States common law. The genealogy of M’Intosh is examined to identify influences that are not fully apparent on the face of the case. International jurisprudential interpretations of the legal definition of genocide are summarized and used as …

Resource Access And Equity In Humboldt County (How Social Myth Becomes Social Fact), Colton J. Hubbard

Cal Poly Humboldt theses and projects

Rural areas of Northern California have gone without health and social services for decades. The shortcomings of local services have given rise to the idea that there are no services in these rural and isolated communities. Conditions and beliefs have brought up two important questions. The first question is how can access and knowledge of available services be improved in rural areas? The second question is, through what mechanisms do communities develop their facts?

To address the previous questions, I worked with the primary health and social service provider in Humboldt County, CA. We developed a database of local services …

Characterizing The Relationship Of Lgl1 And Akt In Migration Of Murine Neural Stem And Progenitor Cells, Natalie Pedicino

Cal Poly Humboldt theses and projects

Asymmetric cell division and migration are critical for neural stem cell differentiation and brain development. When these processes are dysregulated in neural progenitor cells (NPCs), developmental defects and diseases like glioma can result. Lgl1 is a tumor suppressor gene that was first characterized in Drosophila neuroblasts (Strand et al., 1994). It is best known for its regulation of asymmetric cell division through its association with the Par complex. The PI3K/AKT signaling cascade is involved in cellular migration and is also regulated by Par signaling. Unpublished data from the Sprowles laboratory suggests a potential role of Lgl1 in migration and other …

Does The Thatcher Effect Extend To Infant Faces?, Sarang Jew

Cal Poly Humboldt theses and projects

Decades of research on the mechanisms of face processing have demonstrated that humans rely heavily on configural processing strategies when viewing faces. However, this work has been done using almost exclusively adult facial stimuli. More recently, researchers have proposed that infant faces may elicit different neural activity and behavioral responses than adult faces. These observed differences may start at the very early stages of face processing (i.e., the structural encoding occurring within 200ms of seeing a face). However, no studies to date have explored potential differences in processing strategies used for infant faces compared to adult faces. The current study …

Geographic And Seasonal Variation Of Flying Squirrel Vocalizations In California, Travis A. Farwell

Cal Poly Humboldt theses and projects

Advancements in bioacoustics field studies have further elucidated spatial, temporal, and behavioral aspects of otherwise-cryptic species, as well as offering insights into species communication. The discovery of high-frequency vocalizations in North American flying squirrels in particular has allowed researchers to use ultrasonic acoustic recorders to detect these cryptic species in the wild. Investigations into vocalizations of northern flying squirrels (Glaucomys sabrinus) and southern flying squirrels (G. volans) have highlighted call type variation between species and the potential use of recorders as a tool to examine vocal activity patterns. However, high-frequency vocalizations had yet to be quantitatively …

Comparing Molecular Methods To Estimate Fish Stomach Contents And Gastric Evacuation Rates: Implications For Measuring The Impacts Of Predation On Central Valley Chinook Salmon, Cory M. Dick

Cal Poly Humboldt theses and projects

Juvenile Chinook Salmon (Oncorhynchus tshawytscha) migrating through the Sacramento – San Joaquin Delta (the Delta) in central California have higher mortality rates than salmonids migrating through other west coast estuaries. Some hypotheses for high mortality rates include entrainment into water export facilities, physical alterations of the river system, and predation. Of these factors, predation is considered the least understood but may have the largest impact. Predation from large populations of non-native piscivorous fishes in the Delta is believed to effect abundances of Central Valley Chinook salmon, however sufficient data supporting this hypothesis is scarce. In this study, I …

Restorative Practices In Education: A Case Study, Emily Morris

Cal Poly Humboldt theses and projects

Literature shows that restorative justice practices, over time, are an effective practice for reducing negative student behaviors. This study will examine teacher and staff viewpoints on restorative practices and how they are being implemented on our campus. Additionally, this study will explore what impact restorative practices have on our campus, according to teachers and staff. My goal is to answer some of the questions that were unanswered through the literature. For instance, do the restorative justice consequences have a positive impact on student behavior? Do the staff feel that the current system, which uses restorative practices, is effective in dealing …

Nā Pua Makani Wind Farm: The Shifting Winds Of Renewable Development In HawaiʻI, George Webster Ross Iv

Cal Poly Humboldt theses and projects

In 2015, Hawaiʻi set the most ambitious renewable energy portfolio goal in the nation by vowing to reach 100% renewable energy by 2045. Since then, many renewable energy development projects in Hawaiʻi have been met with strong community opposition, including the Nā Pua Makani wind farm (NPM) in Kahuku. The aim of this project is to analyze the process timeline of NPM to identify factors in the development process that contributed to organized protest, and to offer recommendations for improving the process. In order to get a full picture of the events throughout the Nā Pua Makani project’s timeline, my …

Market Surveillance To Support Quality Assurance And Consumer Protection For The Solar Payg Products Market In East And West Africa, Hamidah Naishur Nakimuli

Cal Poly Humboldt theses and projects

Off-grid Pay As You Go (PAYG) solar products have become one of the fastest-growing approaches to providing basic electricity services to off-grid households not only in Sub-Saharan Africa but also in many other parts of the world with limited or no access to the grid connection. However, sustainably growing the PAYG solar industry requires paying close attention to product quality from the point of manufacturing to the end user. This research examines how to best design market surveillance programs that ensure quality in off-grid PAYG solar products and strengthen the implementation and enforcement of quality standards in the off-grid solar …

Degradation And Nitrogen Cycling In The Context Of Biodiversity-Ecosystem Function Relationships In The Inquiline Bacterial Community Of Darlingtonia Californica, Megan Teigen

Cal Poly Humboldt theses and projects

Biodiversity-ecosystem function (BEF) research aims to explain how species and their environments interact with each other. Microbial communities engage in vital biogeochemical pathways in a variety of natural ecosystems, and yet there are large knowledge gaps about the specific metabolic pathways in which they are involved. Degradation specifically contributes to nitrogen cycling globally through the breakdown of large organic nitrogen compounds into small inorganic nitrogen that is necessary for the survival of many other organisms. In this study, I focused on the degradative function of the inquiline microbial communities found within the carnivorous pitcher plant, Darlingtonia californica. Darlingtonia grows in …

A Preliminary Study For The Development Of Free Weight Back Squat Muscular Fitness Reference Norms For Adults Aged 19-29, Eden G. Marquez

Cal Poly Humboldt theses and projects

The barbell back squat is a simple and common resistance training exercise that is used to evaluate muscular fitness. Its use as an evaluative method for muscular fitness in the general population is limited due to a lack of published reference values for this free weight exercise in the general population. This study presents reference values for the back squat muscular fitness in healthy active young adults (aged 19-29). This data is made of 399 subjects (51% male/49% female). Mean ±SD for participants in anthropometric data were 23.1±2.8 years of age, 73.0±12.9 kg weight, 170.6±9.4 cm height, and 25.0±3.4 body …

Determining Haplotype Specific X Chromosome Inactivation State And Related Epigenetic Features In Female X-Linked Genes, Ariah Dawn Mackie

Cal Poly Humboldt theses and projects

Females with heterozygous X-linked mutations are prone to pseudo-haploinsufficiency because random X chromosome inactivation (XCI) silences one of their two X chromosomes. A prior study explored the theory that reactivating the silenced healthy allele could be a treatment for pseudo-haploinsufficient females. The next step was to evaluate this approach in a clinically relevant stem cell model of the rare neurological disease CDKL5 Deficiency Disorder (CDD). It was necessary to validate X-inactivation state with respect to CDKL5 allele expression in one of these models. We explored CDKL5 allele expression in two populations of CDD female patient-derived induced pluripotent stem cells (iPSCs) …

Escherichia Coli And Salmonella Sp. In Domestic Cattle And Wild Roosevelt Elk: Fecal Pathogens At The Wildlife-Domestic Interface, Emily A. Buck

Cal Poly Humboldt theses and projects

Direct or indirect contact between domestic populations of animals and wildlife carries an inherent risk for transmission of pathogens that cause infectious disease. In Humboldt and Del Norte counties of northern California, ongoing conflict between ranchers and Roosevelt elk groups results from elk use of ranching pastures and pastures on private land. Fecal samples from elk in association with cattle, cattle, and from elk not in known association with cattle were assessed for the presence of bacteria Salmonella enterica and pathogenic Escherichia coli to assess whether association with cattle increases risk of infection for elk. Group identity (one of the …

Prevalence Of Rickettsia Sp. Phylotype G022 And Rickettsia Tillamookensis In Ixodes Pacificus Nymphs From Northern California, Erin Rose Trent

Cal Poly Humboldt theses and projects

Back in 2011 an unknown Rickettsia species was discovered in adult Ixodes pacificus and became known as Rickettsiaspecies phylotype G022. Preliminary analyses placed it among the Spotted Fever Group Rickettsia, indicating unknown pathogenicity. Another Rickettsia species previously found in I. pacificus, R. tillamookensis, was only recently the subject of research efforts after its original discovery in the 1960s. The main focus of this research was to determine the prevalence of phylotype G022 in nymphal I. pacificus to gain further insight into this tick-Rickettsia relationship. The prevalence of R. tillamookensis was also a topic of this …

Block Rewards, Carried Interests, And Other Valuation Quandaries In Taxing Compensation, Henry M. Ordower

All Faculty Scholarship

In this article, Ordower contextualizes block rewards litigation with historical failures to tax compensation income paid in kind. Tax fairness principles demand current taxation of the noneconomically diluting block rewards’ market value.

Book Review Of Shaping The Bar: The Future Of Attorney Licensing, Marsha Griggs, Andrea A. Curcio

All Faculty Scholarship

In Shaping the Bar: The Future of Attorney Licensing, Professor Joan Howarth issues a clarion call to the academy, the legal community, and the judiciary to reform the way we license lawyers in the United States. In this book Howarth identifies the current crisis in law licensing, the history of racism that created this crisis, and the tools available to address it. Shaping the Bar challenges our entrenched notions of professional identity, and it forces us to confront vulnerabilities in attorney self-regulation. It does so in a manner that will stir even those not immersed in the current debate about …

What Covid-19 Laid Bare: Adventures In Workers’ Compensation Causation, Michael C. Duff

All Faculty Scholarship

This essay performs a close analysis of workers’ compensation coverage of COVID-19 and arrives at the conclusion that it should not be “impossible” to prove in a legal sense that an employee’s COVID-19 was caused by work. Scientific proof is not the same as legal proof: workers’ compensation law has never required that claims must be supported by irrefutable scientific proof of workplace causation. Yet repeatedly one heard this suggestion during public discussion on workers’ compensation coverage of employees.

Still, there is good evidence that even when workers’ compensation undisputedly covers work-related disease employers seldom pay benefits (and states do …

The Role Of Glis3 In Zebrafish Endocrine Development And Regeneration, Tasha Swenney

Murray State Theses and Dissertations

Maintenance of proper blood glucose homeostasis is governed by the endocrine cells of the pancreas. Dysregulation of blood glucose is characteristic of the disease, diabetes mellitus. Relatively little is known about the molecular mechanisms that underlie diabetes. The genes associated with more common forms of diabetes remain more enigmatic and likely have less direct roles in blood glucose homeostasis such as glucose sensing, insulin secretion, and β cell maintenance. GLIS3, a transcription factor involved in pancreatic development as well as the transcriptional regulation of insulin has been identified as a risk locus for type 1 and type 2 diabetes …

Kentucky Agricultural Education Teachers’ Perceived Barriers Of Delivering Instruction Through Internet-Based Distance Learning Amid The Covid-19 Pandemic, Jeci Crane-Bohannon

Murray State Theses and Dissertations

In the spring of 2020, the COVID-19 pandemic brought about a multitude of challenges around the world. Mass closures of public places seemed to happen overnight and instantaneously. Essential workers kept the world afloat to the best of their abilities, but the harsh reality quickly settled in that education was not considered essential in the view of a worldwide pandemic. Educators worked continue the education of their pupils while trying to minimize movement and limit social gatherings leaving schools around the world reeling to find their ground in an abrupt switch from in-person learning to internet-based, distance education. Globally, the …