Digital Commons Network^™

Relationship Between Student-Centered, Active Learning Strategies And Student Success In An Undergraduate Nursing Course, Camden Seal

Walden Dissertations and Doctoral Studies

In 2010, the Institute of Medicine issued a report calling for the transformation of undergraduate nursing education to prepare new graduates for the complexities of practice. To improve preparation for practice, faculty responded by incorporating student-centered, active learning strategies (SCALS); however, the effectiveness of SCALS has not been examined. The purposes of this descriptive correlational study, guided by Brunner’s constructivist theory, were to determine the relationship between (a) a nurse educator’s use of SCALS and the percent of students that successfully completed the course, (b) an educator’s self-perception of their learner-centeredness and the use of SCALS, and (c) an educator’s …

Impact Evaluation Of The Brfss In New York On Obesity Prevention For Weight Loss Among Women, Nikisha Skeete

Walden Dissertations and Doctoral Studies

Abstract Obesity has increased among the adult population, specifically women, in the United States within the past few decades. While the increase in obesity has been linked to a lack of physical activity and poor dietary intake, obesity lacks contextual analysis within adult women as a group. The purpose of this quantitative study was to examine the impact of the Behavioral Risk Factor Surveillance System (BRFSS) on obesity prevention for weight loss in women. Health behavior change theory, the transtheoretical theory model, and the health behavior model guided this study. The research questions were designed to examine whether modifiable lifestyle …

Effective Leadership Strategies To Engage Employees, Wanda Trujillo Smith

Walden Dissertations and Doctoral Studies

Businesses in the United States lose millions of dollars annually due to low employee performance. However, leaders who develop effective strategies to engage employees may increase employee performance and productivity. Grounded in Khan's theory of employee engagement, the purpose of this qualitative descriptive study was to explore strategies health managers use to engage employees. Participants were eight health care managers from two locations in the northeast region of the United States who demonstrated successful strategies to engage employees. Data were collected from semistructured interviews. The themes that emerged from the thematic analysis were (a) transparency, (b) training, and (c) effective …

School Social Workers’ Perceptions Of The Effectiveness Of Truancy Interventions For Primary School Students, Laniesha Stephens-Dunn

Walden Dissertations and Doctoral Studies

Academic performance is a growing concern for students in kindergarten through Grade 3 (K-3) in the United States, especially those students with a high number of unauthorized absences (i.e., a high truancy rate). When students are absent from school, they may have a lower chance of succeeding academically compared to students with better attendance. School social workers can help these students address barriers to attendance, such as student or family member health, poverty, and psychological and social concerns, and could benefit from more insight on how to effectively engage parents, students, school personnel, and community agencies in eliminating truancy. The …

Elementary Teachers’ Perspectives Of Direct Instruction With More Rigorous Mathematics Standards, Sharon Denise Taylor

Walden Dissertations and Doctoral Studies

AbstractMajestic County Schools (pseudonym), a large southeastern school district, has implemented changes in instruction to align with more rigorous state and national mathematics standards. The rigor of the new standards has led to changes in instruction to help students master the standards with evidence from the state-wide standardized test. Although the district has made curricular changes, over one-third of the students in Grades 3-5 at Flint Elementary are not mastering grade-level standards. This basic qualitative study focuses on one elementary school within the district. The purpose was to understand how teachers implement direct instruction (DI) strategies in the classroom to …

Chronic Obstructive Pulmonary Disease 30-Day Readmission Rates In California, Illinois, And New York, Theresa Teverbaugh

Walden Dissertations and Doctoral Studies

AbstractThe Centers for Medicare and Medicaid Services (CMS) have implemented financial penalties to reduce hospital readmissions for various conditions, including chronic obstructive pulmonary disease (COPD). As a result, hospital administrators explore ways to prevent financial penalties for excessive COPD 30-day hospital readmissions. The purpose of this quantitative study was to determine if there was a correlation between hospital Medicare reimbursement, quality-of-care measures related to patient satisfaction, and 30-day readmissions rates for COPD patients in California, Illinois, and New York. The quality-of-care measures included communication with nurses, communication with doctors, the hospital staff's responsiveness, and medicine communication. The secondary data were …

African American Women Leader Perspectives On Advancement Strategies In A Community College System, Laquanda Rena Thomas

Walden Dissertations and Doctoral Studies

AbstractAfrican American women are not retained or advanced in the community college system, resulting in an underrepresentation of African American women in administrative decision-making roles. The purpose of this basic qualitative study was to examine the experiences of African American female leaders in the community college setting and to explore the strategies that these women used to obtain these positions. Semistructured interviews were conducted with seven African American women in decision-making roles within a southeastern state’s community college system. Critical race theory and Black feminist theory helped to inform how race and gender impacted the selection of strategies used by …

Fourth-Grade Writing Teachers' Perceptions Of Learner-Centered Strategies, April Lorraine Townsend

Walden Dissertations and Doctoral Studies

Writing is a fundamental skill needed for academic success and is considered a lifelong tool. Most students in the United States, however, do not meet grade-level proficiency in writing. Since 2015, the fourth-grade writing performance has not exceeded 50% proficient at the study site. The purpose of this basic qualitative study was to explore fourth-grade writing teachers’ perceptions of learner-centered instructional writing strategies and to identify best practices that can be shared via professional development. The conceptual framework was based on Weimer’s learner-centered principles. The research questions focused on exploring fourth-grade writing teachers’ perceptions of learner-centered writing instructional strategies and …

Correlation Of Meaning Making And Complex Trauma In Women Trafficked For Sex, Brenda Louise Tracey

Walden Dissertations and Doctoral Studies

AbstractThe trafficking of women and girls into the sex industry is one of the world’s fastest growing crimes against humanity. The psychological impact of human trafficking for the purpose of sexual exploitation on survivors has not been widely studied, creating a gap in the literature that merits further research to understand the processes of survivor rehabilitation and community. The purpose of this study was to analyze the relationship between complex posttraumatic stress disorder and having purpose in life among U.S. female citizens who were trafficked into the sex industry. Frankl’s theory of finding meaning was paired with Park’s theory of …

Project Management Communication Strategies To Engage Stakeholders And Improve Project Performance, Joshua Ukoha Ukoha

Walden Dissertations and Doctoral Studies

Project managers’ ineffective stakeholder communication strategies lead to unsuccessful project performance. Project managers who fail to implement appropriate communication strategies can experience less engagement of their stakeholders, reduced project performance, and decreased sustainability. Grounded in the stakeholder theory, the purpose of this qualitative single case study was to explore the communication strategies project managers use to engage stakeholders and improve project performance. Participants were five project managers who successfully used communication strategies to engage stakeholders and improve project performance. Data were collected from semistructured interviews, company archival documents, and field notes and were analyzed using thematic data analysis. Four themes …

Barriers In Quality Healthcare Delivery In The Veterans Healthcare Systems, Kelly A. Walker

Walden Dissertations and Doctoral Studies

The VHA and Department of Veterans Affairs (DVA) have been labeled negligent in providing healthcare for U.S. veterans. Strategies to resolve the problems included legislative changes, watchdog responsibilities, and removal of top officials within the VA. The case studies presented underscore reported problems within Veterans Healthcare Systems. The present research was conducted to determine if the negligence was the result of a toxic work environment and whether the problems continue to affect healthcare delivery to U.S. veterans. Beccaria’s Rational Choice Theory served as the theoretical basis of the research. A mixed method, transformative design was used to conduct the study. …

Strategies Automotive Purchasing Managers Use For Managing Material Costs, Obundah Wenah

Walden Dissertations and Doctoral Studies

AbstractBusiness leaders continually face challenges with the rising cost of materials. Automotive purchasing managers need to develop strategies to manage the cost of materials. Grounded in resource dependency theory, the purpose of this qualitative multiple case study was to explore strategies purchasing leaders in the automotive industry use for managing material costs. Data collection included semistructured interviews and documentation, including purchasing policies and directives. The participants comprised four automotive purchasing managers who formulated and implemented material cost strategies. Five themes were identified using thematic analysis: (a) negotiation, (b) total cost of ownership, (c) reducing design complexity, (d) supplier strategic relationship, …

Allied Health Professionals’ Lived Experiences Concerning Organizational Justice And Inclusion, Jozette A. Wood

Walden Dissertations and Doctoral Studies

AbstractThe lived experiences of allied health assistants (AHAs) are not well understood regarding organizational justice (OJ) and their sense of inclusion within their workplace. Although, OJ and inclusion have been an area of study among scholars for over a decade; the amount of literature supporting AHAs perceptions of these constructs is limited. The purpose of this phenomenological study was to gain a deeper understanding of AHAs’ perceptions of the components of OJ (i.e., distributive, and procedural) and the potential implications for their sense of inclusion. Justice judgment theory provided the theoretical framework for this study. Three primary research questions were …

Fidelity Of Implementation Of A Balanced Literacy Program In The Elementary Classroom, Shalonda Young

Walden Dissertations and Doctoral Studies

AbstractThe local problem is that literacy in the target school district continues to rank below the state average and the fidelity of implementation (FOI) of balanced literacy (BL) has not been addressed since BL was initiated in 2014 to address student literacy achievement. Teachers reported limited professional development (PD) and lack of motivation to implement BL as designed. The purpose of this basic qualitative research study was to explore elementary English language arts (ELA) teachers’ and support staff personnel’s perceptions of the FOI of a BL program in the target school district ELA classrooms to determine in what ways the …

Relationship Between Healthcare Provider Communication And Preventable 30-Day Copd Readmission Rates, Jonathan Butler

Walden Dissertations and Doctoral Studies

AbstractThe Centers for Medicare and Medicaid Services implemented the Hospital Readmission Reduction Program in 2012. Ten years later, hospitals across the United States have had negligible improvement in reducing preventable 30-day hospital readmissions for COPD patients. Healthcare, specifically the hospital setting, consists of complex processes and procedures. Not one process or procedure is the sole cause of correcting excessive preventable 30-day readmissions of patients with COPD. The essential elements of provider communication were studied using the Complex Adaptive Systems theory in this quantitative study. Each fundamental element of provider communication was the independent variable, and the preventable 30-day COPD excessive …

Elementary Teacher Perceptions Of Blended Learning In The Digital Classroom, Sarah Cummings

Walden Dissertations and Doctoral Studies

Blended learning is an instructional model in which instruction is delivered using a combination of traditional teaching methods and online learning materials such as digital textbooks, virtual textbooks, and teacher-made videos. The problem was that elementary teachers in local schools were not implementing blended learning as intended by the school’s improvement plan. The purpose of this study was to examine the perspectives of elementary teachers in Grades 3-5 who have experience using blended learning. The framework for the study is the complex adaptive blended learning system (CABLS) because it helps examine the blended learning elements and the changes that result …

Outcome Measure Of Female Inmates In West Amazon, Carlos Eduardo Siqueira, Luiz C De Abreu, Italla M Pinheiro Bezerra

Gastón Institute Publications

Introduction: the prison system in the Brazilian state of Acre, located in the Western region of the Amazon, is a branch of the criminal justice system that has been suffering from issues such as overcrowding and growth in internal organized crime. The prevalence of these matters directly affects the resocialization of prisoners and inhibits the successful re-engineering of their social values and beliefs. Objective: to analyze the epidemiological profile of jailed women in the State of Acre, Brazil. Methods: in a cross-sectional descriptive study, 129 participants were recruited from female penitentiaries in the state of Acre. Conducted between August and …

Working With Others In The Mentoring Relationship System, Thomas E. Keller

School of Social Work Faculty Publications and Presentations

A mentoring relationship typically doesn’t operate in isolation. Even youth who want or need additional support from a mentor are bound to have many other important people in their lives, such as parents and other caregivers, siblings, teachers, and peers. Consequently, a mentor already may have or may need to establish relationships with other people in the mentee’s network of support. Because these other individuals, and a mentor’s interactions with them, have the potential to enhance or detract from the mentoring experience, they are all important parts of the “mentoring relationship system.”

This chapter outlines important considerations for how to …

Dose Accumulation For Mr-Guided Adaptive Radiotherapy: From Practical Considerations To State-Of-The-Art Clinical Implementation, Brigid A Mcdonald, Cornel Zachiu, John Christodouleas, Mohamed A Naser, Mark Ruschin, Jan-Jakob Sonke, Daniela Thorwarth, Daniel Létourneau, Neelam Tyagi, Tony Tadic, Jinzhong Yang, X Allen Li, Uffe Bernchou, Daniel E Hyer, Jeffrey E Snyder, Edyta Bubula-Rehm, Clifton D Fuller, Kristy K Brock

Faculty, Staff and Student Publications

MRI-linear accelerator (MR-linac) devices have been introduced into clinical practice in recent years and have enabled MR-guided adaptive radiation therapy (MRgART). However, by accounting for anatomical changes throughout radiation therapy (RT) and delivering different treatment plans at each fraction, adaptive radiation therapy (ART) highlights several challenges in terms of calculating the total delivered dose. Dose accumulation strategies-which typically involve deformable image registration between planning images, deformable dose mapping, and voxel-wise dose summation-can be employed for ART to estimate the delivered dose. In MRgART, plan adaptation on MRI instead of CT necessitates additional considerations in the dose accumulation process because MRI …

Serglycin Is Involved In Tgf-Β Induced Epithelial-Mesenchymal Transition And Is Highly Expressed By Immune Cells In Breast Cancer Tissue, Marta Tellez-Gabriel, Xavier Tekpli, Trine M Reine, Beate Hegge, Stephanie R Nielsen, Meng Chen, Line Moi, Lisa Svartdal Normann, Lill-Tove R Busund, George A Calin, Gunhild M Mælandsmo, Maria Perander, Achilleas D Theocharis, Svein O Kolset, Erik Knutsen

Faculty, Staff and Student Publications

Serglycin is a proteoglycan highly expressed by immune cells, in which its functions are linked to storage, secretion, transport, and protection of chemokines, proteases, histamine, growth factors, and other bioactive molecules. In recent years, it has been demonstrated that serglycin is also expressed by several other cell types, such as endothelial cells, muscle cells, and multiple types of cancer cells. Here, we show that serglycin expression is upregulated in transforming growth factor beta (TGF-β) induced epithelial-mesenchymal transition (EMT). Functional studies provide evidence that serglycin plays an important role in the regulation of the transition between the epithelial and mesenchymal phenotypes, …

Translating Mentoring Interventions Research Into Practice: Evaluation Of An Evidence-Based Workshop For Research Mentors On Developing Trainees’ Scientific Communication Skills, Erin K Dahlstrom, Christine Bell, Shine Chang, Hwa Young Lee, Cheryl B Anderson, Annie Pham, Christine Maidl Pribbenow, Carrie A Cameron

Faculty, Staff and Student Publications

A key part of keeping doctoral and postdoctoral trainees in STEM research careers is mentoring. Our previous research indicates that mentoring trainees in scientific communication (SC) skill development increases research career intention through two social-cognitive constructs, self-efficacy in and outcome expectations for acquiring SC skills, as well as science identity. While many mentor training interventions exist, no programs focus on developing SC skills specifically. The "Scientific Communication Advances Research Excellence" (SCOARE) program trains mentors to address trainee scientific communication (SC) skill development as an innovative approach to increase trainee research career persistence. The SCOARE training is a half-day workshop for …

Pathogenic Tau Accelerates Aging-Associated Activation Of Transposable Elements In The Mouse Central Nervous System, Paulino Ramirez, Gabrielle Zuniga, Wenyan Sun, Adrian Beckmann, Elizabeth Ochoa, Sarah L Devos, Bradley Hyman, Gabriel Chiu, Ethan R Roy, Wei Cao, Miranda Orr, Virginie Buggia-Prevot, William J Ray, Bess Frost

Faculty, Staff and Student Publications

Transposable elements comprise almost half of the mammalian genome. A growing body of evidence suggests that transposable element dysregulation accompanies brain aging and neurodegenerative disorders, and that transposable element activation is neurotoxic. Recent studies have identified links between pathogenic forms of tau, a protein that accumulates in Alzheimer's disease and related "tauopathies," and transposable element-induced neurotoxicity. Starting with transcriptomic analyses, we find that age- and tau-induced transposable element activation occurs in the mouse brain. Among transposable elements that are activated at the RNA level in the context of brain aging and tauopathy, we find that the endogenous retrovirus (ERV) class …

Transcriptomic-Assisted Immune And Neoantigen Profiling In Premalignancy, Kyle Chang, Florencia Mcallister, Eduardo Vilar

Faculty, Staff and Student Publications

Immune-based cancer therapies such as checkpoint inhibitors (CPI) and vaccines have been increasingly studied across different cancer types. Response to such therapies depends on a number of factors such as mutational burden, neoantigen load, presence of tumor infiltrating lymphocytes, among others. Next-generation sequencing (NGS) technologies are particularly attractive to interrogate the immune response compared to traditional assays such as qRT-PCR and immunohistochemistry (IHC) because they enable the discovery of neoantigens and simultaneous profiling of immune infiltration using gene expression on a large scale. Current approaches in immune profiling utilizes whole-exome sequencing (WES) for human leukocyte allele (HLA) typing and neoantigen …

Surgical Management Of Brain Metastasis: Challenges And Nuances, Chibawanye I Ene, Sherise D Ferguson

Faculty, Staff and Student Publications

Brain metastasis is the most common type of intracranial tumor. The contemporary management of brain metastasis is a challenging issue and traditionally has carried a poor prognosis as these lesions typically occur in the setting of advanced cancer. However, improvement in systemic therapy, advances in radiation techniques and multimodal therapy tailored to the individual patient, has given hope to this patient population. Surgical resection has a well-established role in the management of brain metastasis. Here we discuss the evolving role of surgery in the treatment of this diverse patient population.

High-Resolution Metabolomics Of Exposure To Tobacco Smoke During Pregnancy And Adverse Birth Outcomes In The Atlanta African American Maternal-Child Cohort, Youran Tan, Dana Boyd Barr, P Barry Ryan, Veronika Fedirko, Jeremy A Sarnat, Audrey J Gaskins, Che-Jung Chang, Ziyin Tang, Carmen J Marsit, Elizabeth J Corwin, Dean P Jones, Anne L Dunlop, Donghai Liang

Faculty, Staff and Student Publications

Exposure to tobacco smoke during pregnancy has been associated with a series of adverse reproductive outcomes; however, the underlying molecular mechanisms are not well-established. We conducted an untargeted metabolome-wide association study to identify the metabolic perturbations and molecular mechanisms underlying the association between cotinine, a widely used biomarker of tobacco exposure, and adverse birth outcomes. We collected early and late pregnancy urine samples for cotinine measurement and serum samples for high-resolution metabolomics (HRM) profiling from 105 pregnant women from the Atlanta African American Maternal-Child cohort (2014-2016). Maternal metabolome perturbations mediating prenatal tobacco smoke exposure and adverse birth outcomes were assessed …

Progression Free Survival Prediction For Head And Neck Cancer Using Deep Learning Based On Clinical And Pet/Ct Imaging Data, Mohamed A Naser, Kareem A Wahid, Abdallah S R Mohamed, Moamen Abobakr Abdelaal, Renjie He, Cem Dede, Lisanne V Van Dijk, Clifton D Fuller

Faculty, Staff and Student Publications

Determining progression-free survival (PFS) for head and neck squamous cell carcinoma (HNSCC) patients is a challenging but pertinent task that could help stratify patients for improved overall outcomes. PET/CT images provide a rich source of anatomical and metabolic data for potential clinical biomarkers that would inform treatment decisions and could help improve PFS. In this study, we participate in the 2021 HECKTOR Challenge to predict PFS in a large dataset of HNSCC PET/CT images using deep learning approaches. We develop a series of deep learning models based on the DenseNet architecture using a negative log-likelihood loss function that utilizes PET/CT …

Deep-Learning-Based Generation Of Synthetic 6-Minute Mri From 2-Minute Mri For Use In Head And Neck Cancer Radiotherapy, Kareem A Wahid, Jiaofeng Xu, Dina El-Habashy, Yomna Khamis, Moamen Abobakr, Brigid Mcdonald, Nicolette O' Connell, Daniel Thill, Sara Ahmed, Christina Setareh Sharafi, Kathryn Preston, Travis C Salzillo, Abdallah S R Mohamed, Renjie He, Nathan Cho, John Christodouleas, Clifton D Fuller, Mohamed A Naser

Faculty, Staff and Student Publications

Background: Quick magnetic resonance imaging (MRI) scans with low contrast-to-noise ratio are typically acquired for daily MRI-guided radiotherapy setup. However, for patients with head and neck (HN) cancer, these images are often insufficient for discriminating target volumes and organs at risk (OARs). In this study, we investigated a deep learning (DL) approach to generate high-quality synthetic images from low-quality images.

Methods: We used 108 unique HN image sets of paired 2-minute T2-weighted scans (2mMRI) and 6-minute T2-weighted scans (6mMRI). 90 image sets (~20,000 slices) were used to train a 2-dimensional generative adversarial DL model that utilized 2mMRI as input and …

Head And Neck Cancer Primary Tumor Auto Segmentation Using Model Ensembling Of Deep Learning In Pet/Ct Images, Mohamed A Naser, Kareem A Wahid, Lisanne V Van Dijk, Renjie He, Moamen Abobakr Abdelaal, Cem Dede, Abdallah S R Mohamed, Clifton D Fuller

Faculty, Staff and Student Publications

Auto-segmentation of primary tumors in oropharyngeal cancer using PET/CT images is an unmet need that has the potential to improve radiation oncology workflows. In this study, we develop a series of deep learning models based on a 3D Residual Unet (ResUnet) architecture that can segment oropharyngeal tumors with high performance as demonstrated through internal and external validation of large-scale datasets (training size = 224 patients, testing size = 101 patients) as part of the 2021 HECKTOR Challenge. Specifically, we leverage ResUNet models with either 256 or 512 bottleneck layer channels that demonstrate internal validation (10-fold cross-validation) mean Dice similarity coefficient …

Deep Learning Auto-Segmentation Of Cervical Skeletal Muscle For Sarcopenia Analysis In Patients With Head And Neck Cancer, Mohamed A Naser, Kareem A Wahid, Aaron J Grossberg, Brennan Olson, Rishab Jain, Dina El-Habashy, Cem Dede, Vivian Salama, Moamen Abobakr, Abdallah S R Mohamed, Renjie He, Joel Jaskari, Jaakko Sahlsten, Kimmo Kaski, Clifton D Fuller

Faculty, Staff and Student Publications

Background/purpose: Sarcopenia is a prognostic factor in patients with head and neck cancer (HNC). Sarcopenia can be determined using the skeletal muscle index (SMI) calculated from cervical neck skeletal muscle (SM) segmentations. However, SM segmentation requires manual input, which is time-consuming and variable. Therefore, we developed a fully-automated approach to segment cervical vertebra SM.

Materials/methods: 390 HNC patients with contrast-enhanced CT scans were utilized (300-training, 90-testing). Ground-truth single-slice SM segmentations at the C3 vertebra were manually generated. A multi-stage deep learning pipeline was developed, where a 3D ResUNet auto-segmented the C3 section (33 mm window), the middle slice of the …

Evaluation Of Deep Learning-Based Multiparametric Mri Oropharyngeal Primary Tumor Auto-Segmentation And Investigation Of Input Channel Effects: Results From A Prospective Imaging Registry, Kareem A Wahid, Sara Ahmed, Renjie He, Lisanne V Van Dijk, Jonas Teuwen, Brigid A Mcdonald, Vivian Salama, Abdallah S R Mohamed, Travis Salzillo, Cem Dede, Nicolette Taku, Stephen Y Lai, Clifton D Fuller, Mohamed A Naser

Faculty, Staff and Student Publications

Background/purpose: Oropharyngeal cancer (OPC) primary gross tumor volume (GTVp) segmentation is crucial for radiotherapy. Multiparametric MRI (mpMRI) is increasingly used for OPC adaptive radiotherapy but relies on manual segmentation. Therefore, we constructed mpMRI deep learning (DL) OPC GTVp auto-segmentation models and determined the impact of input channels on segmentation performance.

Materials/methods: GTVp ground truth segmentations were manually generated for 30 OPC patients from a clinical trial. We evaluated five mpMRI input channels (T2, T1, ADC, Ktrans, Ve). 3D Residual U-net models were developed and assessed using leave-one-out cross-validation. A baseline T2 model was compared to mpMRI models (T2 + T1, …