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2022

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Electroacupuncture Ameliorates Inflammatory Response Induced By Retinal Ischemia-Reperfusion Injury And Protects The Retina Through The Dor-Bdnf/Trkb Pathway, Runjie Guo, Yongjie Zhang, Yue Geng, Ping Chen, Tiantian Fu, Yong Xia, Ren Zhang, Yuan Zhu, Jingling Jin, Nange Jin, Hong Xu, Xuesong Tian Jan 2022

Electroacupuncture Ameliorates Inflammatory Response Induced By Retinal Ischemia-Reperfusion Injury And Protects The Retina Through The Dor-Bdnf/Trkb Pathway, Runjie Guo, Yongjie Zhang, Yue Geng, Ping Chen, Tiantian Fu, Yong Xia, Ren Zhang, Yuan Zhu, Jingling Jin, Nange Jin, Hong Xu, Xuesong Tian

Faculty, Staff and Student Publications

Objectives: Retinal ischemia-reperfusion injury (RIRI) is the common pathological basis of many ophthalmic diseases in the later stages, and inflammation is the primary damage mechanism of RIRI. Our study aimed to assess whether electroacupuncture (EA) has a protective effect against RIRI and to elucidate its related mechanisms.

Methods: A high-intraocular pressure (HIOP) model was used to simulate RIRI in Wistar rats. EA was applied to the EA1 group [Jingming (BL1) + Shuigou (GV26)] and the EA2 group [Jingming (BL1) + Hegu (LI4)] respectively for 30 min starting immediately after the onset of reperfusion and repeated (30 min/time) at 12 h …


Intellectual Property, Independent Creation, And The Lockean Commons, Mala Chatterjee Jan 2022

Intellectual Property, Independent Creation, And The Lockean Commons, Mala Chatterjee

Faculty Scholarship

Copyrights and patents are differently structured intellectual property rights in different kinds of entities. Nonetheless, they are widely regarded by U.S. scholars as having the same theoretical underpinnings. Though scholars have sought to connect philosophical theories of property to intellectual property, with a particular interest in the labor theory of John Locke, these explorations have not sufficiently probed copyrights’ and patents’ doctrinal differences or their philosophical implications for the theories explored. This Article argues that a defining difference between copyrights and patents has normative significance for the framework of Lockean property theory: namely, that copyright law treats independent creation as …


Accommodating Parents, Joshua Gupta-Kagan Jan 2022

Accommodating Parents, Joshua Gupta-Kagan

Faculty Scholarship

The child protection legal system is supposed to work towards the reunification of parents and children in foster care through individualized services to help parents raise their children safely. But that legal system has long been criticized for frequent and severe invasions into the family integrity rights of parents with disabilities and their children, treating parental disabilities as grounds for permanent separation instead of individual characteristics to be accommodated. Several years ago, it seemed that the law was turning. In 2015, the U.S. Departments of Health and Human Services and Justice issued joint guidance stating that the Americans with Disabilities …


Effects Of Socioeconomic Status, Demographic Characteristics, And Education On Sarcopenic Obesity, Moruf Oladele Olaleye Jan 2022

Effects Of Socioeconomic Status, Demographic Characteristics, And Education On Sarcopenic Obesity, Moruf Oladele Olaleye

Walden Dissertations and Doctoral Studies

The general problem is that although the body of research about obesity is robust, there is a lack of research addressing the problem of sarcopenic obesity. Specifically, there is a lack of research examining the statistical significance of the relationship between the independent variables of socioeconomic status, demographic characteristics, and education and the dependent variable of sarcopenic obesity. This research may advance practice and policy by lending support for developing interventions to address factors that have a statistically significant relationship with sarcopenic obesity. The purpose of this quantitative causal-comparative study was to identify independent variables among socioeconomic, demographic, and education …


Terrorism Preparedness, Collaboration, And Organizational Culture In The National Capital Region, Anderson Percival Padmore Jan 2022

Terrorism Preparedness, Collaboration, And Organizational Culture In The National Capital Region, Anderson Percival Padmore

Walden Dissertations and Doctoral Studies

Abstract Terrorism preparedness is essential for federal, state, and local governments. However, literature indicated that local governments may not be ready to respond to a terrorist event. The purpose of this quantitative study was to determine terrorism preparedness levels related to collaboration in the National Capital Region (NCR) of the United States to determine first responders’ perspectives regarding challenges of organizational change. The research questions for this study concentrated on the evaluation of terrorism- preparedness and organizational changes among first response agencies since 2014, Schein’s ideas of organizational cultural change were the theoretical foundation. Four NCR public safety agencies were …


Type Of Union And Reproductive Health Influence On Domestic Violence In Sierra Leone, Yvonne Rowe Jan 2022

Type Of Union And Reproductive Health Influence On Domestic Violence In Sierra Leone, Yvonne Rowe

Walden Dissertations and Doctoral Studies

Domestic violence (DV) is one of the most hidden but prevalent public health concerns affecting women of childbearing age in Africa, despite ongoing prevention initiatives. Lack of power and control in the household is a significant precursor of DV in women, especially in sub-Saharan Africa. While poverty, gender inequality, and societal norms have been identified as directly related to DV, the factors of type of union and reproductive health choice remain unexplored. This quantitative study with a cross-sectional design assessed the relationship between the type of union, female contraceptive use, and type of DV amongst women in Sierra Leone. Anchored …


Comparison Of Three Exercise Interventions With And Without Gemcitabine Treatment On Pancreatic Tumor Growth In Mice: No Impact On Tumor Infiltrating Lymphocytes, Priti Gupta, Charles F Hodgman, Claudia Alvarez-Florez, Keri L Schadler, Melissa M Markofski, Daniel P O'Connor, Emily C Lavoy Jan 2022

Comparison Of Three Exercise Interventions With And Without Gemcitabine Treatment On Pancreatic Tumor Growth In Mice: No Impact On Tumor Infiltrating Lymphocytes, Priti Gupta, Charles F Hodgman, Claudia Alvarez-Florez, Keri L Schadler, Melissa M Markofski, Daniel P O'Connor, Emily C Lavoy

Faculty, Staff and Student Publications

Exercise has been shown to slow pancreatic tumor growth, but whether exercise interventions of differing volume or intensity yield differential effects on tumor outcomes is unknown. In this study, we compared three exercise training interventions implemented with and without chemotherapy on pancreatic tumor growth in mice. Methods: Male C57BL/6 mice (6-8 weeks old) were subcutaneously inoculated with pancreatic ductal adenocarcinoma tumor cells (PDAC 4662). Upon tumor detection, mice received gemcitabine 15 mg/kg intraperitoneally 3 days/week and were assigned to exercise: high volume continuous exercise (HVCE), low volume continuous exercise (LVCE), high intensity interval training (HIIT), or sedentary (SED). HVCE ran …


Cancer Treatment-Induced Nad+ Depletion In Premature Senescence And Late Cardiovascular Complications, Priyanka Banerjee, Elizabeth A Olmsted-Davis, Anita Deswal, Minh Th Nguyen, Efstratios Koutroumpakis, Nicholas L Palaskas, Steven H Lin, Sivareddy Kotla, Cielito Reyes-Gibby, Sai-Ching J Yeung, Syed Wamique Yusuf, Momoko Yoshimoto, Michihiro Kobayashi, Bing Yu, Keri Schadler, Joerg Herrmann, John P Cooke, Abhishek Jain, Eduardo Chini, Nhat-Tu Le, Jun-Ichi Abe Jan 2022

Cancer Treatment-Induced Nad+ Depletion In Premature Senescence And Late Cardiovascular Complications, Priyanka Banerjee, Elizabeth A Olmsted-Davis, Anita Deswal, Minh Th Nguyen, Efstratios Koutroumpakis, Nicholas L Palaskas, Steven H Lin, Sivareddy Kotla, Cielito Reyes-Gibby, Sai-Ching J Yeung, Syed Wamique Yusuf, Momoko Yoshimoto, Michihiro Kobayashi, Bing Yu, Keri Schadler, Joerg Herrmann, John P Cooke, Abhishek Jain, Eduardo Chini, Nhat-Tu Le, Jun-Ichi Abe

Faculty, Staff and Student Publications

Numerous studies have revealed the critical role of premature senescence induced by various cancer treatment modalities in the pathogenesis of aging-related diseases. Senescence-associated secretory phenotype (SASP) can be induced by telomere dysfunction. Telomeric DNA damage response induced by some cancer treatments can persist for months, possibly accounting for long-term sequelae of cancer treatments. Telomeric DNA damage-induced mitochondrial dysfunction and increased reactive oxygen species production are hallmarks of premature senescence. Recently, we reported that the nucleus-mitochondria positive feedback loop formed by p90 ribosomal S6 kinase (p90RSK) and phosphorylation of S496 on ERK5 (a unique member of the mitogen-activated protein kinase family …


Aj Bellidodeluna, Claudia Sanchez Jan 2022

Aj Bellidodeluna, Claudia Sanchez

Latinx Civil Rights

Assistant Dean A.J. Bellido de Luna recounts his higher educational experience as a white passing Cuban Latino. He covers his upbringing, where his family is from, what it means to be Latino to him, and his experience as a Latino faculty member in higher education.


Daniel Gutiérrez, Yairy Mendez Jan 2022

Daniel Gutiérrez, Yairy Mendez

Latinx Civil Rights

In this interview, Daniel discusses how Mexican American Studies is interpreted in Texas public schools and how this affected his own education and cultural identity. Daniel also shares how the COVID-19 pandemic affected his education during his transition from secondary to tertiary school.


Virginia Ibarra, Arthur Reyes Jan 2022

Virginia Ibarra, Arthur Reyes

Latinx Civil Rights

Virginia discusses events of her childhood such as crossing the U.S.-Mexico border at Laredo, Texas and working as a babysitter. She also explains how she moved to Houston to work in a sheet metal factory and finally settled in the San Antonio area. Virginia recalls the processes of gaining residency and citizenship while pursuing her education.


Abilene Solano, Yairy Mendez Jan 2022

Abilene Solano, Yairy Mendez

Latinx Civil Rights

Abilene Solano discusses the interpretation of Mexican American Studies in public school education. She also shares insights about her experiences attending public school and some of the challenges she faced being a first-generation student. Abilene relays how her graduating cohort was affected by the COVID-19 pandemic and how that affected her everyday life


Development Of An Insomnia Assessment Guideline For Bipolar Disorder, Daniel Oyewusi Oyewole Jan 2022

Development Of An Insomnia Assessment Guideline For Bipolar Disorder, Daniel Oyewusi Oyewole

Walden Dissertations and Doctoral Studies

AbstractBipolar disorder (BD) affects more than 1% of the world’s population regardless of race, sex, ethnicity, or socioeconomic status. BD is a severe and chronic mental illness characterized by insomnia, depressed and elevated mood, racing thoughts, mood swings, anxiety and depression, and suicide. Insomnia is prevalent in BD and occurs across all stages of BD, yet no guidelines exist. The clinical practice guideline entitled the Insomnia Assessment Guideline for Bipolar Disorder (IAGBD) was developed using best-practice evidence from the published literature. The IAGBD is a step-by-step process for assessing insomnia in bipolar patients. Clinicians follow a series of questions in …


The Impact Of Wrongful Death Lawsuits On Police Officers, Richard Kevin Powers Jan 2022

The Impact Of Wrongful Death Lawsuits On Police Officers, Richard Kevin Powers

Walden Dissertations and Doctoral Studies

Law enforcement has become known as one of the most stressful occupations. Stress can have negative impacts on police officers’ professional careers and their personal life. This qualitative research revealed the unseen pressure of wrongful death lawsuits involving police officers, especially those cleared of any criminal wrongdoings. The study explored the police officers' perceptions while gaining knowledge from their lived experiences of how wrongful death lawsuits impacted them professionally and personally. This qualitative study was guided by the person-in-environment theory, which means that the environment can affect the police officer. In return, the police officer can affect the environment. The …


Hiring Managers’ Perceptions Of Hiring Adults With Intellectual And Developmental Disabilities, Carol L. Price-Guthrie Jan 2022

Hiring Managers’ Perceptions Of Hiring Adults With Intellectual And Developmental Disabilities, Carol L. Price-Guthrie

Walden Dissertations and Doctoral Studies

AbstractMultiple barriers impede individuals with intellectual and developmental disabilities (IDDs) from gaining access to jobs that are competitive and integrated and that offer them a living wage. People with IDDs experience an inability to develop necessary employable skills and may be affected by hiring manager perceptions and lack of awareness of available job opportunities. The purpose of this basic qualitative study was to explore hiring managers’ perceptions of hiring individuals with IDDs in competitive integrated employment (CIE) settings in Tennessee. Critical disability theory was used to frame this study. Nine hiring managers in Tennessee who have worked with people with …


Cost-Saving Strategies For Municipal Wastewater Treatment Plant Managers, Rosalie Rivera Jan 2022

Cost-Saving Strategies For Municipal Wastewater Treatment Plant Managers, Rosalie Rivera

Walden Dissertations and Doctoral Studies

Wastewater treatment plant (WWTP) managers deal with increased costs while facing declining budgets to meet treated water standards. Biological disinfection processes comprise 65% of a typical WWTP's energy use and are of significant concern to WWTP managers. Grounded in the resource-based view theory and Six Sigma DMAIC approach as the conceptual framework, the purpose of this qualitative embedded single case study was to explore strategies WWTP managers use to lower water disinfection costs. Data were collected using semistructured interviews with four plant managers of the same organization in the central region municipalities of Florida who successfully implemented strategies to lower …


Fire Safety Education And Increasing Functioning Smoke Detectors In Residential Apartments, Enrique Fernandez Robinson Jan 2022

Fire Safety Education And Increasing Functioning Smoke Detectors In Residential Apartments, Enrique Fernandez Robinson

Walden Dissertations and Doctoral Studies

The lack of functioning smoke detectors poses significant life safety risks to people in low-income residential communities. In 2019, a fire incident occurred in an urban Maryland community due to the lack of a functioning smoke detector. Although no deaths or injuries resulted, there was significant property damage and resident displacement. The purpose of this study was to assist a local fire department in an urban area of the state of Maryland with developing and implementing a fire safety community outreach program designed to reduce the percentage of residential homes in a low-income community without functioning smoke detectors. A qualitative …


Relationship Changes Of African Americans With Nontraditional Spiritual Practices, Della Sanders Jan 2022

Relationship Changes Of African Americans With Nontraditional Spiritual Practices, Della Sanders

Walden Dissertations and Doctoral Studies

Researchers have explored the subject of belongingness for decades. However, there is limited research on how belongingness may change for African Americans who transitioned from traditional Christianity to other spiritual practices. In this study, the relationship changes (in terms of family, friends, significant others, and former church relationships) of African Americans who identify as spiritual but not religious (SBNR) after leaving traditional Christianity were explored. The theoretical framework of the social connectedness theory was used to explore the need for belongingness to avoid social isolation and loneliness within a social network. Six African American Generation Xers, four women and two …


Staff Education On Perinatal Depression, Kirenia Santiuste Jan 2022

Staff Education On Perinatal Depression, Kirenia Santiuste

Walden Dissertations and Doctoral Studies

Perinatal depression (PND) is a global mood disorder affecting women transitioning into parenthood and is closely related to extensive psychosocial and financial consequences for the family. Ten to twenty percent of new mothers in the US are affected by PND in the year after giving birth. The problem identified for this Doctor of Nursing Practice project was the need for staff education on knowledge of and screening for PND in the obstetrical clinic for which the project was developed in a southeastern state of the US. Using the analysis, design, development, implementation, and evaluation model, the purpose of this Doctor …


English Language Learner Teachers’ Perspectives Of Professional Development And Their Implementation Of Instructional Practices, Cara Nicole Scales-Judkowitz Jan 2022

English Language Learner Teachers’ Perspectives Of Professional Development And Their Implementation Of Instructional Practices, Cara Nicole Scales-Judkowitz

Walden Dissertations and Doctoral Studies

An increasing number of U.S. teachers of English Language Learners (ELL) across the nation are not receiving adequate in-service training to provide instruction within students’ zone of proximal development (ZPD). Vygotsky’s ZPD is the difference between what a person can achieve when acting alone and what the same person can achieve when acting with support from someone else. ELL instructional practices should be implemented in ELL students’ ZPD to ensure adequate academic performance. A lack of training is a local problem for a school district in the state of Florida. The purpose of this basic qualitative study was to explore …


Parents’ Perspectives On Early Intervention For Children With Autism, Tiffany Schmidt Jan 2022

Parents’ Perspectives On Early Intervention For Children With Autism, Tiffany Schmidt

Walden Dissertations and Doctoral Studies

The purpose of this study was to analyze parent perspectives on early intervention services for children with autism. Research has shown a significant positive impact of early intervention on children with autism. A total of eight parents participated in this basic qualitative study guided by social cognitive theory. Participating parents were those whose child had an autism diagnosis and were receiving or had received early intervention services in Southeast Michigan. Data analysis included establishing themes and codes to organize the data into categories. Thematic analysis was applied by analyzing interview transcripts. The research questions used to collect data addressed parents’ …


The Effect Of Instructional Coaching On Third-Grade Reading Achievement, Jane Ann Schmidt Jan 2022

The Effect Of Instructional Coaching On Third-Grade Reading Achievement, Jane Ann Schmidt

Walden Dissertations and Doctoral Studies

Instructional coaching has been implemented in schools to improve student achievement; however, literature shows a lack of evidence of the efficacy of improving student reading achievement. The problem addressed in this study was that school districts have implemented instructional coaching to improve student reading achievement, but the effectiveness was unknown. The purpose of this quantitative study was to examine the effect of instructional coaching on third-grade reading achievement. Guided by Walberg’s theory of achievement, the overall research question investigated the effect of instructional coaching on third-grade reading achievement. In this quantitative, comparative study, ratio-scale data from students who received instructional …


Use Of An Intelligent Tutoring System And Academic Performance In An Online College Course For Pre-Nursing Students, Mark Schmidt Jan 2022

Use Of An Intelligent Tutoring System And Academic Performance In An Online College Course For Pre-Nursing Students, Mark Schmidt

Walden Dissertations and Doctoral Studies

The efficacy of intelligent tutoring systems (ITS) for undergraduate college level courses was not well established and specifically, the Pearson Dynamic Study Modules (PDSM) program had not been investigated locally. The purpose of this quantitative study was to determine whether the use of an ITS designed with a cognitive learning approach; the PDSM, would enhance pre-nursing student academic performance. The multiple attribute decision making and the human plausible reasoning theories grounded the study. A non-experimental quantitative research design was used to determine whether there was a difference in the assessment scores of pre-nursing students in a college level anatomy and …


Relationship Between Student-Centered, Active Learning Strategies And Student Success In An Undergraduate Nursing Course, Camden Seal Jan 2022

Relationship Between Student-Centered, Active Learning Strategies And Student Success In An Undergraduate Nursing Course, Camden Seal

Walden Dissertations and Doctoral Studies

In 2010, the Institute of Medicine issued a report calling for the transformation of undergraduate nursing education to prepare new graduates for the complexities of practice. To improve preparation for practice, faculty responded by incorporating student-centered, active learning strategies (SCALS); however, the effectiveness of SCALS has not been examined. The purposes of this descriptive correlational study, guided by Brunner’s constructivist theory, were to determine the relationship between (a) a nurse educator’s use of SCALS and the percent of students that successfully completed the course, (b) an educator’s self-perception of their learner-centeredness and the use of SCALS, and (c) an educator’s …


Impact Evaluation Of The Brfss In New York On Obesity Prevention For Weight Loss Among Women, Nikisha Skeete Jan 2022

Impact Evaluation Of The Brfss In New York On Obesity Prevention For Weight Loss Among Women, Nikisha Skeete

Walden Dissertations and Doctoral Studies

Abstract Obesity has increased among the adult population, specifically women, in the United States within the past few decades. While the increase in obesity has been linked to a lack of physical activity and poor dietary intake, obesity lacks contextual analysis within adult women as a group. The purpose of this quantitative study was to examine the impact of the Behavioral Risk Factor Surveillance System (BRFSS) on obesity prevention for weight loss in women. Health behavior change theory, the transtheoretical theory model, and the health behavior model guided this study. The research questions were designed to examine whether modifiable lifestyle …


Effective Leadership Strategies To Engage Employees, Wanda Trujillo Smith Jan 2022

Effective Leadership Strategies To Engage Employees, Wanda Trujillo Smith

Walden Dissertations and Doctoral Studies

Businesses in the United States lose millions of dollars annually due to low employee performance. However, leaders who develop effective strategies to engage employees may increase employee performance and productivity. Grounded in Khan's theory of employee engagement, the purpose of this qualitative descriptive study was to explore strategies health managers use to engage employees. Participants were eight health care managers from two locations in the northeast region of the United States who demonstrated successful strategies to engage employees. Data were collected from semistructured interviews. The themes that emerged from the thematic analysis were (a) transparency, (b) training, and (c) effective …


School Social Workers’ Perceptions Of The Effectiveness Of Truancy Interventions For Primary School Students, Laniesha Stephens-Dunn Jan 2022

School Social Workers’ Perceptions Of The Effectiveness Of Truancy Interventions For Primary School Students, Laniesha Stephens-Dunn

Walden Dissertations and Doctoral Studies

Academic performance is a growing concern for students in kindergarten through Grade 3 (K-3) in the United States, especially those students with a high number of unauthorized absences (i.e., a high truancy rate). When students are absent from school, they may have a lower chance of succeeding academically compared to students with better attendance. School social workers can help these students address barriers to attendance, such as student or family member health, poverty, and psychological and social concerns, and could benefit from more insight on how to effectively engage parents, students, school personnel, and community agencies in eliminating truancy. The …


Elementary Teachers’ Perspectives Of Direct Instruction With More Rigorous Mathematics Standards, Sharon Denise Taylor Jan 2022

Elementary Teachers’ Perspectives Of Direct Instruction With More Rigorous Mathematics Standards, Sharon Denise Taylor

Walden Dissertations and Doctoral Studies

AbstractMajestic County Schools (pseudonym), a large southeastern school district, has implemented changes in instruction to align with more rigorous state and national mathematics standards. The rigor of the new standards has led to changes in instruction to help students master the standards with evidence from the state-wide standardized test. Although the district has made curricular changes, over one-third of the students in Grades 3-5 at Flint Elementary are not mastering grade-level standards. This basic qualitative study focuses on one elementary school within the district. The purpose was to understand how teachers implement direct instruction (DI) strategies in the classroom to …


Chronic Obstructive Pulmonary Disease 30-Day Readmission Rates In California, Illinois, And New York, Theresa Teverbaugh Jan 2022

Chronic Obstructive Pulmonary Disease 30-Day Readmission Rates In California, Illinois, And New York, Theresa Teverbaugh

Walden Dissertations and Doctoral Studies

AbstractThe Centers for Medicare and Medicaid Services (CMS) have implemented financial penalties to reduce hospital readmissions for various conditions, including chronic obstructive pulmonary disease (COPD). As a result, hospital administrators explore ways to prevent financial penalties for excessive COPD 30-day hospital readmissions. The purpose of this quantitative study was to determine if there was a correlation between hospital Medicare reimbursement, quality-of-care measures related to patient satisfaction, and 30-day readmissions rates for COPD patients in California, Illinois, and New York. The quality-of-care measures included communication with nurses, communication with doctors, the hospital staff's responsiveness, and medicine communication. The secondary data were …


African American Women Leader Perspectives On Advancement Strategies In A Community College System, Laquanda Rena Thomas Jan 2022

African American Women Leader Perspectives On Advancement Strategies In A Community College System, Laquanda Rena Thomas

Walden Dissertations and Doctoral Studies

AbstractAfrican American women are not retained or advanced in the community college system, resulting in an underrepresentation of African American women in administrative decision-making roles. The purpose of this basic qualitative study was to examine the experiences of African American female leaders in the community college setting and to explore the strategies that these women used to obtain these positions. Semistructured interviews were conducted with seven African American women in decision-making roles within a southeastern state’s community college system. Critical race theory and Black feminist theory helped to inform how race and gender impacted the selection of strategies used by …