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Articles 5401 - 5430 of 23822
Full-Text Articles in Entire DC Network
An Overview Of The Regulations Of Corporate Social Responsibility (Csr) Labelled Product, Zaid Zaid
An Overview Of The Regulations Of Corporate Social Responsibility (Csr) Labelled Product, Zaid Zaid
Indonesia Law Review
Over the last 5 years, Indonesia has experienced an emergency of illegal products. Most of them are imported products that do not have adequate labeling standards which can adversely affect both domestic or national trade and stakeholders. On the other hand, product labels are one of the most effective ways to detect the legality, safety, and warranty of a product. This article aims to explore and analyze how the role of product labels can protect and cover social interests. In addition, this research also tries to observe how ethics and laws or regulations regulate product labels to provide a moral …
Proteome Phenotypes Discriminate The Growing Location And Malting Traits In Field-Grown Barley, Mahya Bahmani, Angéla Juhász, James Broadbent, Utpal Bose, Mitchell G. Nye-Wood, Ian B. Edwards, Michelle L. Colgrave
Proteome Phenotypes Discriminate The Growing Location And Malting Traits In Field-Grown Barley, Mahya Bahmani, Angéla Juhász, James Broadbent, Utpal Bose, Mitchell G. Nye-Wood, Ian B. Edwards, Michelle L. Colgrave
Research outputs 2022 to 2026
Barley is one of the key cereal grains for malting and brewing industries. However, climate variability and unprecedented weather events can impact barley yield and end-product quality. The genetic background and environmental conditions are key factors in defining the barley proteome content and malting characteristics. Here, we measure the barley proteome and malting characteristics of three barley lines grown in Western Australia, differing in genetic background and growing location, by applying liquid chromatography-mass spectrometry (LC-MS). Using data-dependent acquisition LC-MS, 1571 proteins were detected with high confidence. Quantitative data acquired using sequential window acquisition of all theoretical (SWATH) MS on barley …
Contribution Of Orbitofrontal Cortex Activity To Risky Decision-Making, Daniel Bradley Karmiol Gabriel
Contribution Of Orbitofrontal Cortex Activity To Risky Decision-Making, Daniel Bradley Karmiol Gabriel
Electronic Theses and Dissertations Archive
In this dissertation, I recorded individual neuronal activity from the lateral orbitofrontal cortex of awake, freely moving animals as they behaved in a punishment-based risky decision-making task. In this risky decision-making task, subjects chose between a small food reward and a large food reward associated with either a 0% or 50% risk of a concurrent punishment in the form of a mild footshock. As the risk of punishment increased, subjects reduced choice of the large reward. To fully dissect the neuronal underpinnings throughout the decision-making process, I designed the behavioral paradigm to contain three distinct stages: deliberation, choice selection, and …
Abstract: A Quest For Freedom: The History Of Marronage And Maroon Communities In The United States, 1513-1865, Ainsworth L. Tracey
Abstract: A Quest For Freedom: The History Of Marronage And Maroon Communities In The United States, 1513-1865, Ainsworth L. Tracey
Electronic Theses and Dissertations Archive
A Quest for Freedom: The History of Marronage and Maroon Communities in the United States, 1513-1865, is an examination of marronage or Maroon Societies in North America. The self-emancipated or fugitive slave community and its impact on African American men, women, and children during the slave era is one of the least understood aspects of African American History. The objective of this study is to showcase these self-liberated communities and the Maroon experience in North America. Current research on the subject has revealed that the historical record possesses a wealth of information on the topic which allows for an accurate …
The Dominant Soft Skills That Affect Readiness Of Vocational Graduate In Entering Construction Labor Market, Nathanael Sitanggang, Putri Lynna Adelinna Luthan, Felix Andika Dwiyanto, Satrio Dwi Sanjaya
The Dominant Soft Skills That Affect Readiness Of Vocational Graduate In Entering Construction Labor Market, Nathanael Sitanggang, Putri Lynna Adelinna Luthan, Felix Andika Dwiyanto, Satrio Dwi Sanjaya
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan
This study aims to recognize the dominant soft skills factors that influence the readiness of vocational education graduates to enter the job market in the field of construction. The method used is survey study including samples that consisted of 40 workers graduated from State University of Medan civil engineering diploma 3. The instruments used were the soft skills and the competence readiness questionnaire with reliability coefficients of 0.93 and 0.98. Furthermore, the multiple regression analysis techniques is used to test the hypothesis. The results shows that the soft skills readiness influencing 74% the vocational education skills readiness in entering the …
The Quality Of Rhyme And Rhythm In Song Lyric Translation, Aulia Fitri, Haru Deliana Dewi, Rahayu Surtiati Hidayat
The Quality Of Rhyme And Rhythm In Song Lyric Translation, Aulia Fitri, Haru Deliana Dewi, Rahayu Surtiati Hidayat
Paradigma: Jurnal Kajian Budaya
This research is a development of Low’s theory (2008) on assessing the quality of song lyric translation based on its translation method. The objective of the study is to discover the quality of rhyme and rhythm of song lyrics in the album We Love Disney which have been translated from English to Indonesian. Therefore, this study focuses on the quality of rhyme and rhythm of the translation because these elements are significant parts of the songs. Low’s theory has been applied in the present study to measure the song lyric translation quality using three translation methods: communicative, free, and semantic …
Study Shows An Improved Way To Model Type 2 Diabetes In Mice, Staff
Study Shows An Improved Way To Model Type 2 Diabetes In Mice, Staff
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No abstract provided.
Benetton’S (In)Equality: A Semiotic Reading, Hianly Muljadi, Sonny Angjaya, Joanna Deborah
Benetton’S (In)Equality: A Semiotic Reading, Hianly Muljadi, Sonny Angjaya, Joanna Deborah
Paradigma: Jurnal Kajian Budaya
United Colors of Benetton, or UCB, has been using its advertisements to deliver positive messages and values that the clothing company represents. This article analyzes one of the photographs in Benetton’s campaign for their Spring Summer Collection of 2018. The campaign, which consists of some photographs by Oliviero Toscani, raises the theme of equality of gender and ethnicity. It shows various photographs of both female and male models from different ethnicities. However, it is found that there is one photograph that shows inconsistency with the very value that Benetton wants to convey through their campaign. Based on the semiotic analysis, …
A Review Of The Cultural Gender Norms Contributing To Gender Inequality In Ghana: An Ecological Systems Perspective, Portia Nartey, Ozge Sensoy Bahar, Proscovia Nabunya
A Review Of The Cultural Gender Norms Contributing To Gender Inequality In Ghana: An Ecological Systems Perspective, Portia Nartey, Ozge Sensoy Bahar, Proscovia Nabunya
Journal of International Women's Studies
While significant progress has been made in improving the wellbeing of women and girls around the world, a gender gap still exists between men and women which is very evident in Ghana. Gender inequalities continue to persist in Ghana because of cultural gender norms that exalt and favor men and put women in subordinate and subservient roles. These cultural gender norms hinder women’s development and widen gender inequality between men and women in different system levels of society. Therefore, there is a need to examine the influence of these cultural gender norms on women’s lives using a systems framework to …
Memories, A Process Of Resilience In The Face Of Captivity, Nadia Naboulsi Iskandarani
Memories, A Process Of Resilience In The Face Of Captivity, Nadia Naboulsi Iskandarani
BAU Journal - Society, Culture and Human Behavior
Resilience is the ability to withstand adversity, trauma, stress, and other problems such as depression, family problems and difficult situations in order to be able to survive regardless of the types of shocks suffered. In his novel, Tous les hommes n’habitent pas le monde de la même façon (All men do not inhabit the world in the same way), the French writer Jean-Paul Dubois (Goncourt price-2019) narrates the story of Paul Hansen, locked down in Montreal prison where he shares a 6 square meters cell with Patrick Horton, convicted for murder. Paul Hansen passes time recalling the greatest moments of …
Three Strong Women, By Marie Ndiaye: The Grace Of Resilience, Carole Auroy
Three Strong Women, By Marie Ndiaye: The Grace Of Resilience, Carole Auroy
BAU Journal - Society, Culture and Human Behavior
By taking "three strong women" as heroines, Marie NDiaye brings out the paradoxical strength of characters caught up in the destructive mechanisms of stories with uncertain endings. We perceive in these women the models of a resilience whose restorative grace is inscribed the intersubjective relations of which they are the hearths. This hypothesis invites us to observe how these relationships, threatened by an alienating confusion, get out of it, but also to locate the opaque zones of the narratives which designate the fragility of the process. Resilience could be the faculty of escaping from the dead life, that which makes …
Effect Of Floor Cooling On Sows Under Heat Stress, Javier Flores
Effect Of Floor Cooling On Sows Under Heat Stress, Javier Flores
American Journal of Rising Scholar Activities
With temperatures increasing steadily throughout the last century, the hog farrowing industry is beginning to confront an ongoing dilemma. Temperatures are now exceeding ideal conditions for optimal milk production, as well as maximum litter size. Temperatures that exceed optimal conditions can lead to significant heat stress among sows. Efficiently cooling-down sows, while keeping piglets at ideal temperatures, is the focus of this project. A cooling pad was built with copper pipes inside a high-density polyethylene board, covered by an aluminum plate. Experimental treatments included cool water flowing through the copper pipes at different levels depending on the specific sow. Intervals …
Data Mining To Save The World, Nicole Huddleston
Data Mining To Save The World, Nicole Huddleston
American Journal of Rising Scholar Activities
Data analysts look for patterns and characteristics in the large sets of data being collected under modern electronic conditions. When unusual circumstances occur, patterns within the data can alert oversight personnel to the incident before other traditional warning signs. This work utilized the standard deviation of single signal outputs for analysis. This data mining application was specifically applied to safety within the nuclear power industry.
Purdue Hog Cooling Pad Experience, Marco Baez
Purdue Hog Cooling Pad Experience, Marco Baez
American Journal of Rising Scholar Activities
The demand for food is increasing with the growing population. The pork industry is currently thriving and will continue to prosper as long as sows continue to reproduce. However, the reproduction of pigs is currently facing the problem of heat stress. Environmental temperatures are reaching extremes, and lactating sows produce less milk for offspring when they are in hot weather. The main reason that they produce less is because of undernourishment. Sows eat less when hot, because when they do eat, it actually causes them to heat-up. The goal of the overall cooling pad effort is to reduce the heat …
Spartan Daily, August 30, 2022, San Jose State University, School Of Journalism And Mass Communications
Spartan Daily, August 30, 2022, San Jose State University, School Of Journalism And Mass Communications
Spartan Daily, 2022
Volume 159, Issue 4
Infection Avoidance Behaviors Across Vertebrate Taxa: Patterns, Processes, And Future Directions, Patricia C. Lopes, Susannah S. French, Douglas C. Woodhams, Sandra A. Binning
Infection Avoidance Behaviors Across Vertebrate Taxa: Patterns, Processes, And Future Directions, Patricia C. Lopes, Susannah S. French, Douglas C. Woodhams, Sandra A. Binning
Biology, Chemistry, and Environmental Sciences Faculty Books and Book Chapters
An infected animal can behave, smell, sound, and look very different from a healthy version of itself. The same is true when comparing habitats, food, or water sources contaminated with parasite infectious stages to their uncontaminated counterparts. All these differences provide cues or indications of disease risk and thus allow uninfected animals to modify their behaviors in ways that alter disease transmission. This chapter focuses on prophylactic behaviors: host behaviors that reduce the risk of infection. It provides an overview of how infection avoidance behaviors are triggered, then summarizes the avoidance behaviors known to occur in vertebrates, giving special attention …
Lithic Debitage And Geospatial Analysis Of Hemish Obsidian Procurement And Reduction Strategies In Colonial New Mexico, Adam Vitale
Graduate Masters Theses
This project evaluates Hemish (people of Jemez) obsidian procurement and reduction strategies through an analysis of over two thousand pieces of obsidian debitage and geospatial analysis of potential hiking pathways. This diachronic analysis provides insight on the variation of the Hemish people’s usage of obsidian for stone tool production from four markedly different social climates which are referenced throughout this study as the pre-Colonial Period (AD 1300-1539), the Early Colonial Period (AD 1540-1680), the Revolt Period (AD 1680-1692), and the Late Colonial or Reconquista Period (AD 1694-1696). Now called the Jemez Plateau, this area is characterized by a series of …
Changing To Stay The Same: Spatial Analyses Of Tobacco Pipes From 18th- And 19th-Century Eastern Pequot Households, Stephen P. Anderson
Changing To Stay The Same: Spatial Analyses Of Tobacco Pipes From 18th- And 19th-Century Eastern Pequot Households, Stephen P. Anderson
Graduate Masters Theses
This thesis examines indigenous smoking practices using European white ball clay pipe disposal patterns on the Eastern Pequot reservation in North Stonington, Connecticut. The Eastern Pequot used European-made smoking pipes in their day-to-day life during the 18th and 19th centuries. Material and spatial analyses of pipes and their disposal patterns detail how Eastern Pequot smoking practices changed and continued in the North American colonial world.
Smoking and tobacco use are unique in North American colonialism as the practice originates with the continent’s Indigenous people and was transformed by the English. Questions around cultural change and continuity in smoking due to …
“The Circle Of Your Acquaintance”: Early 19th Century Ceramic Symbolism And Constructions Of Black Womanhood At The Boston-Higginbotham House, Nantucket, Ma, Lissa J. Herzing
“The Circle Of Your Acquaintance”: Early 19th Century Ceramic Symbolism And Constructions Of Black Womanhood At The Boston-Higginbotham House, Nantucket, Ma, Lissa J. Herzing
Graduate Masters Theses
During the early 19th century, ideologies of womanhood were beginning to solidify in the national discourse of the United States. The concept of domesticity, the process of homemaking through material and spiritual means, was a key aspect of womanhood during this time, the transition from the Early Republic to the Victorian period. These ideals were prescribed to white middle- and upper-class women but were altered by Black women to serve their needs and adopted to combat negative stereotypes of Black people in a society permeated with racism. This was evident in the work of Maria W. Stewart, the first Black …
Polymorphism & Parasites: Structure, Diversity And Selection Of The Mhcii Genes In A Weakly Electric Fish, Brachyhypopomus Occidentalis, Bruna L. Silva
Polymorphism & Parasites: Structure, Diversity And Selection Of The Mhcii Genes In A Weakly Electric Fish, Brachyhypopomus Occidentalis, Bruna L. Silva
Graduate Masters Theses
The major histocompatibility complex (MHC) class II molecules play a key role in inducing an immune response, by presenting foreign peptides to T-lymphocytes. They are considered one of the most polymorphic genes in the vertebrate genome and diversity has been associated with species diversification mediated by parasite, viral and bacterial infections. While MHC genes are well documented in teleost fish, none thus far have been described in the Gymnotiform order – a highly diverse group of neotropical electric fishes. Using a combination of a recently annotated genome and whole genome resequencing data, I identified and characterized both the classical MHCII …
Distinct Sensitivities To Sars-Cov-2 Variants In Vaccinated Humans And Mice, Alexandra C Walls, Laura A Vanblargan, Michael S Diamond, Et Al.
Distinct Sensitivities To Sars-Cov-2 Variants In Vaccinated Humans And Mice, Alexandra C Walls, Laura A Vanblargan, Michael S Diamond, Et Al.
2020-Current year OA Pubs
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019 has led to the development of a large number of vaccines, several of which are now approved for use in humans. Understanding vaccine-elicited antibody responses against emerging SARS-CoV-2 variants of concern (VOCs) in real time is key to inform public health policies. Serum neutralizing antibody titers are the current best correlate of protection from SARS-CoV-2 challenge in non-human primates and a key metric to understand immune evasion of VOCs. We report that vaccinated BALB/c mice do not recapitulate faithfully the breadth and potency of neutralizing antibody responses elicited …
Spatiotemporal Correlation Analysis Of Hydraulic Fracturing And Stroke In The United States, Chuanbo Hu, Bin Liu, Shuo Wang, Zhenduo Zhu, Amelia Adcock, James Simpkins, Xin Li
Spatiotemporal Correlation Analysis Of Hydraulic Fracturing And Stroke In The United States, Chuanbo Hu, Bin Liu, Shuo Wang, Zhenduo Zhu, Amelia Adcock, James Simpkins, Xin Li
2020-Current year OA Pubs
Hydraulic fracturing or fracking has led to a rapid growth of oil and gas production in the United States, but the impact of fracking on public health is an important but underresearched topic. We designed a methodology to study spatiotemporal correlations between the risk of fracking and stroke mortality. An annualized loss expectancy (ALE) model is applied to quantify the risk of fracking. The geographically and temporally weighted regression (GTWR) model is used to analyze spatiotemporal correlations of stroke mortality, fracking ALE, and nine other socioeconomic- and health-related factors. The analysis shows that fracking ALE is moderately correlated with stroke …
A Multitrait Locus Regulates Sarbecovirus Pathogenesis, Alexandra Schäfer, Emma S Winkler, Michael S Diamond, Et Al
A Multitrait Locus Regulates Sarbecovirus Pathogenesis, Alexandra Schäfer, Emma S Winkler, Michael S Diamond, Et Al
2020-Current year OA Pubs
Infectious diseases have shaped the human population genetic structure, and genetic variation influences the susceptibility to many viral diseases. However, a variety of challenges have made the implementation of traditional human Genome-wide Association Studies (GWAS) approaches to study these infectious outcomes challenging. In contrast, mouse models of infectious diseases provide an experimental control and precision, which facilitates analyses and mechanistic studies of the role of genetic variation on infection. Here we use a genetic mapping cross between two distinct Collaborative Cross mouse strains with respect to severe acute respiratory syndrome coronavirus (SARS-CoV) disease outcomes. We find several loci control differential …
Re-Examining Rotavirus Innate Immune Evasion: Potential Applications Of The Reverse Genetics System, Avan Antia, Amanda N Pinski, Siyuan Ding
Re-Examining Rotavirus Innate Immune Evasion: Potential Applications Of The Reverse Genetics System, Avan Antia, Amanda N Pinski, Siyuan Ding
2020-Current year OA Pubs
Rotaviruses represent one of the most successful pathogens in the world, with high infectivity and efficient transmission between the young of many animal species, including humans. To overcome host defenses, rotaviruses have evolved a plethora of strategies to effectively evade the innate immune response, establish initial infection in the small intestine, produce progeny, and shed into the environment. Previously, studying the roles and relative contributions of specific rotaviral factors in innate immune evasion had been challenging without a plasmid-only reverse genetics system. Although still in its infancy, current reverse genetics technology will help address important research questions regarding rotavirus innate …
Historical Study On The Development Of The Weaving Motif Of Bima, West Nusa Tenggara, Indonesia, Nursyahri Ramadhan, Tri Karyono, Zakarias Sukarya Soeteja
Historical Study On The Development Of The Weaving Motif Of Bima, West Nusa Tenggara, Indonesia, Nursyahri Ramadhan, Tri Karyono, Zakarias Sukarya Soeteja
Bahasa dan Seni: Jurnal Bahasa, Sastra, Seni, dan Pengajarannya
This study aims to trace the early history of the Bimanese to identify the weaving and its 10 motifs defined in the Bima Land Customary Law as part of the Bima ethnic characteristics. The study used a qualitative approach with data triangulation (observations, interviews, and documentation). The research result showed that the activity of spinning yarn was known by the Bimanese before the expedition of Sang Bima to the land of the rising sun (Satonda Island, a volcanic area on Sumbawa Island), which became the ancestors of the Bimanese. They used weaving to make clothes, using similar procedures of Javanese …
Caged Animals: The Reproduction Of Social And Educational Inequalities In Indian Secondary Schools, Vishakha Agarwal
Caged Animals: The Reproduction Of Social And Educational Inequalities In Indian Secondary Schools, Vishakha Agarwal
Graduate Doctoral Dissertations
There is a continued crisis in public schooling in India’s low-income and socially disadvantaged communities. Schools are supposed to provide a safe and healthy environment conducive to learning that ultimately helps to disrupt the transmission of intergenerational poverty and leads to social and economic mobility among low-income and socially disadvantaged students. In practice, however, schools have served to disproportionately exclude marginalized populations from attaining quality education. Previous research has revealed that less affluent students attend under-resourced schools in buildings with poor infrastructural facilities and fewer or unqualified teachers (India Infrastructure Report, 2012), where they face hidden normative barriers that negatively …
Increased Anxiety From Fear Of Omicron In China As Compared To North America And Western Europe: A Cross-Sectional Kendall's Tau-B Analysis Using The Generalized Anxiety Disorder 7-Item Questionnaire, Dan Shan, Chang Liu, Shaoyang Li, Yuandian Zheng
Increased Anxiety From Fear Of Omicron In China As Compared To North America And Western Europe: A Cross-Sectional Kendall's Tau-B Analysis Using The Generalized Anxiety Disorder 7-Item Questionnaire, Dan Shan, Chang Liu, Shaoyang Li, Yuandian Zheng
Student Publications
Background: Policies dealing with the Coronavirus Disease 2019 (COVID-19) pandemic vary across the globe, the different governmental responses then affect the public perception of COVID-19. Many unofficial Chinese media outlets frequently spread misinformation about COVID-19 and exaggerated reports of rare sequelae of Omicron for monetization and attention seeking, leading to panics in the Chinese public. In comparison the attitudes toward Omicron in other countries around the world, especially in North America and Western Europe have shifted to a more relaxed stance.
Objective: This article primarily aims to investigate the association between Chinese people’s attitudes toward the potential after-effects of Omicron …
Molecular Analysis Of Short- Versus Long-Term Survivors Of High-Grade Serous Ovarian Carcinoma, Elaine Stur, Emine Bayraktar, Graziela Zibetti Dal Molin, Sherry Y Wu, Lingegowda S Mangala, Hui Yao, Ying Wang, Prahlad T Ram, Sara Corvigno, Hu Chen, Han Liang, Shelley S Tworoger, Douglas A Levine, Susan K Lutgendorf, Jinsong Liu, Kathleen N Moore, Keith A Baggerly, Beth Y Karlan, Anil K Sood
Molecular Analysis Of Short- Versus Long-Term Survivors Of High-Grade Serous Ovarian Carcinoma, Elaine Stur, Emine Bayraktar, Graziela Zibetti Dal Molin, Sherry Y Wu, Lingegowda S Mangala, Hui Yao, Ying Wang, Prahlad T Ram, Sara Corvigno, Hu Chen, Han Liang, Shelley S Tworoger, Douglas A Levine, Susan K Lutgendorf, Jinsong Liu, Kathleen N Moore, Keith A Baggerly, Beth Y Karlan, Anil K Sood
Faculty, Staff and Student Publications
Despite having similar histologic features, patients with high-grade serous ovarian carcinoma (HGSC) often experience highly variable outcomes. The underlying determinants for long-term survival (LTS, ≥10 years) versus short-term survival (STS, < 3 years) are largely unknown. The present study sought to identify molecular predictors of LTS for women with HGSC. A cohort of 24 frozen HGSC samples was collected (12 LTS and 12 STS) and analyzed at DNA, RNA, and protein levels. OVCAR5 and OVCAR8 cell lines were used for in vitro validation studies. For in vivo studies, we injected OVCAR8 cells into the peritoneal cavity of female athymic nude mice. From RNAseq analysis, 11 genes were found to be differentially expressed between the STS and LTS groups (fold change > 2; false discovery rate < 0.01). In the subsequent validation cohort, transmembrane protein 62 (TMEM62) was found to be related to LTS. CIBERSORT analysis showed that T cells (follicular helper) were found at higher levels in tumors from LTS than STS groups. In vitro data using OVCAR5 and OVCAR8 cells showed decreased proliferation with TMEM62 overexpression and positive correlation with a longevity-regulating pathway (KEGG HSA04213) at the RNA level. In vivo analysis using the OVCAR8-TMEM62-TetON model showed decreased tumor burden in mice with high- vs. low-expressing TMEM62 tumors. Our results demonstrate that restoring TMEM62 may be a novel approach for treatment of HGSC. These findings may have implications for biomarker and intervention strategies to help improve patient outcomes
Why Not Both Nature And Nurture: Using Behavioral Genetic Markers As Sentencing Factors, Seely Kaufmann
Why Not Both Nature And Nurture: Using Behavioral Genetic Markers As Sentencing Factors, Seely Kaufmann
Richmond Journal of Law & Technology
On the evening of July 1, 2013, Amos Wells was upset that his pregnant girlfriend, Chanice Reed, would not answer his calls. He then drove to where she, her mother Annette, and ten-year-old brother Eddie, lived. After arguing with Chanice and yelling at the top of his voice in a “bone-chilling scream,” Wells retrieved a handgun from his Chevrolet Tahoe parked in front of the house, and shot Chanice in the front yard as she screamed, “No, no, no.” Her mother then tried to bat the gun away before he shot her too. Further shots were heard before Wells finally …
Thermodynamic And Structural Quantification Of Metal Ions Binding To The Antimicrobial Peptide Calcitermin, Sohee Choi
Thermodynamic And Structural Quantification Of Metal Ions Binding To The Antimicrobial Peptide Calcitermin, Sohee Choi
Master's Theses
Over the past several decades the number of antibiotic resistant bacteria has grown dramatically, in part due to the over-prescription of antibiotics. This rise in antibiotic resistance has led to development of novel antibiotics. An attractive alternative to treat bacterial infections may be the use of antimicrobial peptides due their little-known resistance from bacteria. One such peptide is calcitermin (VAIALKAAHYHTHKE), a 15-residue peptide found in human airways. Calcitermin has antimicrobial properties that target Gram-positive bacteria and is most active in acidic buffer (pH 5.4) due to protonation of its three histidine residues, which allows it to interact with the negatively …