Digital Commons Network^™

Modified Messengers: Flatworm Stem Cells And Regeneration Are Guarded By Rna Methylation, Blair W Benham-Pyle

Faculty, Staff and Students Publications

The contribution of RNA modifications to whole-body regeneration remains unclear. In this issue, Dagan et al (2022) show that m6a mRNA pathway components are critically required for stem cell differentiation, survival, and tissue renewal in the planarian Schmidtea mediterranea.

Environmental Educators’ Perceptions Of Inaugural Louisiana State Department Of Education Environmental Education Standards And Accompanying Environmental Education Endorsement Plan: A Multiple Case Study Approach, Abigail Greer

LSU Master's Theses

Increasing environmental literacy through environmental education is an integral approach to fighting many of the environmental challenges facing Louisiana. The State Department of Education in Louisiana has released two initiatives to increase environmental literacy in the state while incorporating nonformal environmental education into formalized k-12 education. The first initiative is a set of Key Principles and Concepts (KPCs) in environmental education, which is aimed at providing standards to nonformal environmental educators in Louisiana. The second initiative, the Louisiana Environmental Education Advancement Plan (LEEAP), accompanies the KPCs and provides an opportunity for nonformal environmental education organizations to achieve endorsement through partnership …

Secreted Fas Decoys Enhance The Antitumor Activity Of Engineered And Bystander T Cells In Fas Ligand-Expressing Solid Tumors, Pradip Bajgain, Alejandro G Torres Chavez, Kishore Balasubramanian, Lindsey Fleckenstein, Premal Lulla, Helen E Heslop, Juan Vera, Ann M Leen

Faculty, Staff and Students Publications

T-cell immunotherapy has demonstrated remarkable clinical outcomes in certain hematologic malignancies. However, efficacy in solid tumors has been suboptimal, partially due to the hostile tumor microenvironment composed of immune-inhibitory molecules. One such suppressive agent abundantly expressed in solid tumors is Fas ligand (FasL), which can trigger apoptosis of Fas-expressing effector cells such as T cells and natural killer (NK) cells. To alleviate this FasL-induced suppression of tumor-specific immune cells in solid tumors, we describe here the development of a Fas decoy that is secreted by engineered cells upon activation and sequesters the ligand, preventing it from engaging with Fas on …

Review Of Structural Color In The Genus Chrysochroa Dejean, 1833 (Coleoptera: Buprestidae), Able Chow

LSU Master's Theses

The jewel beetles, (Coleoptera: Buprestidae Leach, 1815), is the eighth most speciose coleopteran family, with the majority of its members possessing diverse bright, saturated structural coloration of multilayer origin. This study focuses on the genus Chrysochroa Dejean, 1833, which includes some of the most brilliantly and charismatically colored buprestid species. While members of Chrysochroa are prised by entomologists amateurs and professional and are well-represented in museum collections, the evolution and ecology of their structural color remain underexplored. Twenty-eight select taxa including exemplars from all 13 subgenera of Chrysochroa were investigated to provide an overview of the objective optical properties and …

Identification Of Quantitative Trait Loci (Qtls) For Resistance To Bacterial Leaf Streak: Xanthomonas Translucens Using Qtl And Association Mapping In Three Populations Of Soft Red Winter Wheat, Benjamin Tyler Meritt

LSU Doctoral Dissertations

Bacterial leaf streak (BLS) and black chaff, caused by Xanthomonas translucens pv. undulosa (Xtu), can be a very destructive disease of wheat, especially in the warmer, wetter areas of the Southeastern U.S. Yield losses of up to 40 percent have been recorded in some cases in southern wheat growing regions. With no effective agronomic or chemical method of disease control, identification of genetic resistance is seen as a promising solution. Three soft red winter wheat populations (GAWN, ARK-SNP, and AGS 2060- AGS 2035 DH) representative of soft red winter wheat germplasm in the southeastern U.S. developed by …

The Presence Of Microcystin In The Northwest Indiana Watershed, Breeann Mild

The Journal of Purdue Undergraduate Research

No abstract provided.

Investigating The Role Of The Hedgehog Pathway In Connection To Atrazine Endocrine Disruption, Anusha Kv Lakshmi Dharmavathi

The Journal of Purdue Undergraduate Research

No abstract provided.

Impact Of Adolescent Social Isolation On Adult, Binge-Like Ethanol Consumption And Plasma Corticosterone In High-Alcohol-Preferring Mice, Eva Cullins

The Journal of Purdue Undergraduate Research

Adolescent stress exposure increases the likelihood of alcohol misuse and alcohol use disorder (AUD) in adulthood; however, it is not clear how genetic and environmental factors interact to increase risk. This study examined how adolescent social isolation affects adult binge-like ethanol drinking and levels of the stress hormone corticosterone in male and female mice with a genetic predisposition toward high alcohol preference (HAP). Twenty-eight HAP mice were separated into group-housed (GH) and socially isolated (SI) conditions (n = 13, 13). Binge drinking was assessed using a drinking in the dark (DID) procedure. Blood samples were taken before DID and after …

Processing Of Plastic Film From Potato Starch: Effect Of Drying Methods, Kourtney Collier, Samantha Goins, Austin Chirgwin, Isabelle Stanfield

The Journal of Purdue Undergraduate Research

Starch-based plastics are biodegradable, compostable compounds made of starch and plasticizers from natural sources. Their fabrication involves the starch-plasticizer reaction at 70–100°C followed by cooling and drying. Th e most common drying method is air drying (natural convection), which is effective but slow. Th e objective of this work is to study the effect of fast drying (forced convection) on the quality of the plastic film. Th is work compares the effects of drying conditions and drying rate on warpage, shrinkage rate, and presence of bubbles. Five drying methods are studied: (1) natural convection with uncovered petri dish, (2) natural …

Supporting The Protect Initiative, Josh Lefton, Jackson Murray, Ahmed Thabet, Sriram Baireddy, Prakash Shukla, Mridul Gupta, Reagan Becker, Julie Ertle, Tony Doan, Aerin Yang

Purdue Journal of Service-Learning and International Engagement

Recently, medication dosage errors have received more political and media attention. Dosage errors are the most common medical errors, affecting about 1.5 million people annually.

Furthermore, U.S. poison-control centers reported more than 200,000 cases per year of medication errors. These cases result in medical costs of around $3.5 billion, and children under 6 years old constitute approximately 30% of these cases.

The PROTECT Initiative (Preventing Overdoses and Treatment Errors in Children Taskforce) was launched in 2008 as a collaborative effort between public health agencies and patient advocates to minimize dosage errors.

In alignment with the PROTECT Initiative effort, this project …

Uniting For Important Paws: The Independent Cat Society And S.H.I.N.E., Kayla Vasilko

Purdue Journal of Service-Learning and International Engagement

Homeless pets outnumber homeless people 5 to 1; only 1 in 10 animals in animal shelters are spayed or neutered; thus, organizations like the Independent Cat Society (ICS), a non-profit, cage-less, no kill cat shelter are vital community resources (Gaille, 2017). At the ICS, every cat admitted is spayed or neutered and updated on any needed medical treatment; feline overpopulation is addressed through trap, neuter, release (TNR), and additional programs to educate the public on responsible animal care practices (“About the ICS,” 2019). Through volunteerism and two Purdue Service-Learning grants, the Purdue University Northwest student organization S.H.I.N.E (students helping ignite …

An International Survey Of Animals In Schools: Exploring What Sorts Of Schools Involve What Sorts Of Animals, And Educators’ Rationales For These Practices, Helen Lewis, Russell Grigg, Cathryn Knight

People and Animals: The International Journal of Research and Practice

Over recent decades, the use of animal-assisted interventions (AAIs) in educational settings has attracted growing international interest both among educators and the research community. However, there has been little comparative analysis of the demographics of participants and the rationale behind such practices. The aim of this paper is to address this. An anonymous online questionnaire was distributed via social media and other networks. Quanti-tative and qualitative data were collected from 610 participants across 23 countries, mostly from the United Kingdom and North America. In total, 315 (51.6%) participants reported involving animals in their settings. The results show that although animals …

Exploring Children’S Insights About Participating In Recreational Activities With Horses And Farm Animals: Social Emotional Experiences And Belief In Animal Mind, Christine Yvette Tardif-Williams, Renata P. S. Roma

People and Animals: The International Journal of Research and Practice

Research continues to shed light on the impact of children’s interactions with horses in equine-assisted, learning, and therapeutic contexts. However, we know relatively less about the impact of children’s recreational activities with horses and a diversity of farm animals. What is needed is research that explores how recreational programs involving activities with horses and farm animals are perceived by the child participants themselves. This pilot study sought to explore the insights of children who participated in a nine-week recreational program involving activities with horses and farm animals, with a focus on children’s social emotional experiences and belief in animal mind …

Introducing Interdisciplinary Curricula Into Conservation Biology: Exploring Changes In Students’ Perceived Proenvironmental Attitudes And Behaviors, Jasmine Janes, Lindsay J. Mccunn

Journal of Educational Research and Practice

Today, conserving the natural environment is paramount. Educators have been striving to develop pedagogical approaches that facilitate greater engagement in conservation behaviors. However, many of these reforms have been targeted at an institutional level, without necessarily testing whether changes in proenvironmental perceptions, attitudes, or behaviors occur for students. This step seems important when developing conservation biology courses that provide well-rounded education that may better prepare students for future challenges in biodiverse conservation contexts. Our objective was to assess the proenvironmental attitudes and conservation values of undergraduate students enrolled in an undergraduate conservation biology course before and after instruction to determine …

Role Of Invasive Hemodynamics In Shock Management: Is A Pulmonary Artery Catheter Always Necessary?, Ajay J. Kirtane

Journal of Shock and Hemodynamics

The pulmonary artery (PA) catheter can be a useful tool in the management of patients with cardiogenic shock; however, there are challenges with the use of this catheter, and clinicians must balance the risks and benefits. In addition, clinicians must properly interpret data generated from a PA catheter in the context of other data to optimize a patient's hemodynamics.

Using Stories With Families: A Scoping Review, Sam Hadji Cyrous Ph.D. (Candidate), Sofia Valadares Nishiyama Cordeiro, Ana Caroline De Caldas

Counseling and Family Therapy Scholarship Review

This article is the fruit of a systematic scoping review, according to PRISMA precepts. Its objective was to explore the use of stories and other symbolic genre on family therapy settings. Thus, it explains how the researchers made the selection of articles in phases or steps, in a total of six, having a final result of 11 articles, in a time-lapse of 28 years. By the one hand, it was observed a relationship between different techniques that are usually grouped separately and, by the other hand, the disparate way in which the same concepts are confused among researchers, where each …

New Frontiers 2021-2022, University Of Nebraska At Kearney Office Of Graduate Studies And Research

New Frontiers

New Frontiers 2021-2022 Features:

• Extra Enthusiasm - Basheer Qolomany
• Best Thesis Award - Brian Mason
• Passion for the Past - Doug Biggs
• Master of Movement - Noelle Bohaty
• Game Time - Brooke Envick
• True Teacher-Scholar - Phu Vu
• Improving Patient Outcomes - Austin Nuxoll
• Drug Discovery - Mahesh Pattabiraman
• Lasting Impact - Charlie Bicak
• Teaching. Reasearch. Service. - Amy Nebesniak

Carum Carvi Modulates Acetaminophen-Induced Hepatotoxicity: Effects On Tnf-Α, Nf-Κb, And Caspases, Tahir Maqbool Mir, Muneeb U. Rehman, Mohammad Khalid Ashfaq, Wajhul Qamar

Faculty and Student Publications

Carum carvi is a well-known herb traditionally used as a spice in Asian countries. Acetaminophen is a known marketed drug mainly used as an analgesic. It has been scientifically proven that consumption of acetaminophen (paracetamol) is associated with liver toxicity if taken in high doses without medical supervision. The present study evaluated the in vivo antioxidant and hepatoprotective efficacy of Carum carvi against acetaminophen-induced hepatotoxicity in Wistar rats. Our results demonstrate that Carum carvi, at doses (mg/kg) of 100 (D1) and 200 (D2), showed inhibitory properties for DNA-sugar damage, lipid peroxidation, DPPH scavenging, and increased reducing potential in a concentration-dependent …

Rosmarinic Acid Prevents Cisplatin-Induced Liver And Kidney Injury By Inhibiting Inflammatory Responses And Enhancing Total Antioxidant Capacity, Thereby Activating The Nrf2 Signaling Pathway, Yifei Xiang, Min Ji, Liqin Wu, Li Lv

Faculty and Student Publications

Drug-induced liver and kidney damage is an emergent clinical issue that should be addressed. Rosmarinic acid (RA) has obvious anti-inflammatory and antioxidant effects, so we evaluated the anti-inflammatory and antioxidant effects of RA pretreatment on serum and liver and kidney tissues of cisplatin (CP)-treated mice and explored the possible mechanisms. The results showed that RA pretreatment effectively downregulated the serum, liver, and kidney levels of ALT, AST, BUN, and CRE and the inflammatory factors IL-1β, IL-6, and TNF-α, and simultaneously enhanced the total antioxidant capacity of the liver and kidney. RA pretreatment significantly reduced the levels of MPO, MDA, and …

Anti-Phishing Tools: State Of The Art And Detection Efficiencies, M. F. Alghenaim, N. A. Abu Bakar, F. Abdul Rahim

Applied Mathematics & Information Sciences

A phishing attack is a process of obtaining a customers private data, whether by using phishing emails or fake websites. With every new development on the Internet, the attackers means of phishing attacks develop, requiring more powerful phishing tools to counter these attacks. The Internet has become an essential part of the personal and social life of the public and governments, institutions, and companies all over the world. This means that Internet users need tools to protect against phishing attack types and web risks, which may cause personal, institutional, financial, and informational damage. Hence, this study reviews anti-phishing attack tools …

The Centrality Of Data And Compute For Ai Innovation: A Blueprint For The National Research Cloud, Daniel E. Ho, Jennifer King, Russell C. Wald, Christopher Wan

Notre Dame Journal on Emerging Technologies

From the introduction: Artificial intelligence (AI) appears poised to transform the economy across sectors ranging from healthcare and finance to retail and education. What some have coined the “Fourth Industrial Revolution” is driven by three key trends: greater availability of data, increases in computing power, and improvements to algorithm design. First, increasingly large amounts of data have fueled the ability for computers to learn, such as by training an algorithmic language model on all of Wikipedia. Second, better computational capacity (often termed “compute”) and compute capability have enabled researchers to build models that were unimaginable merely ten years ago, spanning …

Note: Structured Psychometrics In Biglaw Talent Acquisition: Ai-Driven Quantitative Fit, Joseph J. Kim

Notre Dame Journal on Emerging Technologies

This Note combines a number of perspectives and disciplines to proffer a unique suggestion toward recognizing better talent and acquiring a new intraindustry competitive edge.

Microfibers: Environmental Problems And Textile Solutions, Js Weis, Falco F De

More Faculty of Science and Engineering Research

Microplastics have become a topic of considerable concern and intensive study over the past decade. They have been found everywhere in the oceans, including the deepest trenches and remotest parts of the Arctic. They are ingested by many animals and some are incorporated into tissues. There is considerable effort in studying what effects they have on marine life. It has become clear that when water samples are collected in ways that prevent most long thin particles from escaping through pores of a net, the most abundant type of microplastics found in water and sediments are microfibers (fibers with dimensions less …

Anti-Phishing Tools: State Of The Art And Detection Efficiencies, M. F. Alghenaim, N. A. Abu Bakar, F. Abdul Rahim

Applied Mathematics & Information Sciences

A phishing attack is a process of obtaining a customers private data, whether by using phishing emails or fake websites. With every new development on the Internet, the attackers means of phishing attacks develop, requiring more powerful phishing tools to counter these attacks. The Internet has become an essential part of the personal and social life of the public and governments, institutions, and companies all over the world. This means that Internet users need tools to protect against phishing attack types and web risks, which may cause personal, institutional, financial, and informational damage. Hence, this study reviews anti-phishing attack tools …

In Defense Of (Virtuous) Autonomous Weapons, Don Howard

Notre Dame Journal on Emerging Technologies

I will argue, we can construct effective means for norming the use of autonomous weapons short of a total ban by building upon the foundation of existing requirements stipulated in Article 36 of Protocol I to the Geneva Conventions that all new weapons technologies be reviewed for compliance with the International Law of Armed Conflict (ILOAC) and International Humanitarian Law (IHL). I begin with a critical review of several of the most commonly encountered arguments in favor of a ban. That is followed by a discussion of the moral opportunities afforded by enhanced autonomy. I conclude with a concrete policy …

Synchronized Diaphragmatic Stimulation For Heart Failure With A Reduced Left Ventricular Ejection Fraction Using The Visone System: A First-In-Patient Study With Extended Population, Ana Jorbenadze Md, Lee R. Goldberg Md, Tamaz Shaburishvili Md, Michel Zuber Md, Michael Mirro Md, Facc, Fhrs, Faha, Marat Fudim Md,Mh

Parkview Heart Institute

Highlights

• Synchronized diaphragmatic stimulation (SDS) is a new extra-cardiac HFrEF therapy
• SDS impacts intrathoracic pressure and pericardial restraint•
• SDS exhibits a favorable safety profile over 1 year of chronic use
• Exercise tolerance and QOL improved with SDS over 1 year
• Early results will soon be validated in a randomized control trial

Abstract

Background

We4: Leisure Quotes, Lance Gibbs Phd

We Exist Series 4: Quotes

Welcome to the fourth exhibit in the series of “We Exist”. In this section we have selected quotes that represent and explain how Maine’s Black residents’ create the processes behind their engagement in particular leisure activities. The quotes also highlight the particular types of leisure activities that Maine’s Black residents suggest that they are involved in. The quotes are taken from transcripts of the oral history project "'Home Is Where I Make It': African American Community and Activism in Greater Portland, Maine”. The interview subjects are all native to Maine or are longtime residents of Maine. The original intent of …

Emerging Harmful Algal Blooms Caused By Distinct Seasonal Assemblages Of A Toxic Diatom, Alexa R. Sterling, Riley D. Kirk, Matthew J. Bertin, Tatiana A. Rynearson, David G. Borkman, Marissa C. Caponi, Jessica Carney, Katherine A. Hubbard, Meagan A. King, Lucie Maranda, Emily J. Mcdermith, Nina R. Santos, Jacob P. Strock, Erin M. Tully, Samantha B. Vaverka, Patrick D. Wilson, Bethany D. Jenkins

Cell and Molecular Biology Faculty Publications

Diatoms in the Pseudo-nitzschia genus produce the neurotoxin domoic acid. Domoic acid bioaccumulates in shellfish, causing illness in humans and marine animals upon ingestion. In 2017, high domoic acid levels in shellfish meat closed shellfish harvest in Narragansett Bay, Rhode Island for the first and only time in history, although abundant Pseudo-nitzschia have been observed for over 60 years. To investigate whether an environmental factor altered endemic Pseudo-nitzschia physiology or new domoic acid-producing strain(s) were introduced to Narragansett Bay, we conducted weekly sampling from 2017 to 2019 and compared closure samples. Plankton-associated domoic acid was quantified by LC-MS/MS and Pseudo-nitzschia …

Spartan Daily, November 1, 2022, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2022

Volume 159, Issue 30

Economic Contribution Of Agriculture And Food To Arkansas’ Gross Domestic Product 1997-2021, Leah English, Jennie Popp

AAES Research Reports and Research Bulletins

Agricultural production, processing, and retail industries are major contributors to Arkansas’ GDP. Agriculture contributes to the state economy through direct agricultural production, value-added processing, and agricultural retail activities. The Agriculture and Food Sector, which is comprised of agricultural production, processing, and retail industries, promotes economic strength through various interactions with other industries. The use of non-agricultural goods and services as inputs into the agricultural sector promotes diversified growth in Arkansas’ economy and thus plays a vital role in maintaining economic stability throughout the state. This report 1) compares the relative size of the Agriculture and Food Sector in Arkansas with …