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2022

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A Comparative Analysis Of Repatriation Of Native American Artifacts And Human Remains Laws In Montana, Usa And Alberta Canada, Helen Cryer Jan 2022

A Comparative Analysis Of Repatriation Of Native American Artifacts And Human Remains Laws In Montana, Usa And Alberta Canada, Helen Cryer

Graduate Student Theses, Dissertations, & Professional Papers

ABSTRACT: Native American and Indigenous communities across the United States and Canada have lost an extensive amount of human remains and sacred artifacts to non-Native people exhuming Native American and Indigenous burial sites that may have been dug up for personal gain, stolen, placed in museums, or left in the hands of non-Native collectors. The repatriation of human remains and sacred artifacts to Native nations can be a lengthy, political, and challenging process yet it is worth the effort for Native people. Native American advocacy and evolving public sentiment toward Native people have led to legislative advancements in the United …


Omega-6 And Omega-3 Fatty Acid-Derived Oxylipins From The Lipoxygenase Pathway In Maternal And Umbilical Cord Plasma At Delivery And Their Relationship With Infant Growth, Maranda Thompson, Arzu Ulu, Ana G. Yuil-Valdes, Maheswari Mukherjee, Melissa K. Thoene, Matthew Van Ormer, Rebecca Slotkowski, Elizabeth Lyden, Ann Anderson-Berry, Corrine K. Hanson, Tara M. Nordgren, Sathish Kumar Natarajan Jan 2022

Omega-6 And Omega-3 Fatty Acid-Derived Oxylipins From The Lipoxygenase Pathway In Maternal And Umbilical Cord Plasma At Delivery And Their Relationship With Infant Growth, Maranda Thompson, Arzu Ulu, Ana G. Yuil-Valdes, Maheswari Mukherjee, Melissa K. Thoene, Matthew Van Ormer, Rebecca Slotkowski, Elizabeth Lyden, Ann Anderson-Berry, Corrine K. Hanson, Tara M. Nordgren, Sathish Kumar Natarajan

Journal Articles: Pediatrics

Omega-3 and omega-6 fatty acids are important for neonatal development and health. One mechanism by which omega-3 and omega-6 fatty acids exert their effects is through their metabolism into oxylipins and specialized pro-resolving mediators. However, the influence of oxylipins on fetal growth is not well understood. Therefore, the objective of this study was to identify oxylipins present in maternal and umbilical cord plasma and investigate their relationship with infant growth. Liquid chromatography-tandem mass spectrometry was used to quantify oxylipin levels in plasma collected at the time of delivery. Spearman's correlations highlighted significant correlations between metabolite levels and infant growth. They …


Living Mysteries: Embodiment Of Divine Knowledge In Jewish Apocalypticism, Andrei Orlov Jan 2022

Living Mysteries: Embodiment Of Divine Knowledge In Jewish Apocalypticism, Andrei Orlov

Theology Faculty Research and Publications

The study explores the early Jewish understanding of divine knowledge as divine presence, which is embodied in major biblical exemplars, such as Adam, Enoch, Jacob, and Moses. It demonstrates that the personification of divine knowledge in early Judaism and, especially, in the Jewish pseudepigrapha reveals a distinct “cultic” way of mediating the divine presence and, consequentially, the divine knowledge that can be designated as the “divine presence’s epistemology.”


Activity Patterns Of The Del Norte Salamander (Plethodon Elongatus): Monitoring Plethodontid Behavior Using Pit Tag Surveys, Sabrina Horrack Jan 2022

Activity Patterns Of The Del Norte Salamander (Plethodon Elongatus): Monitoring Plethodontid Behavior Using Pit Tag Surveys, Sabrina Horrack

Cal Poly Humboldt theses and projects

Semi-fossorial plethodontid salamanders exhibit behavioral plasticity to avoid desiccation, retreating underground to shelter from adverse conditions such as low precipitation and high temperatures. In this study, I used passive integrated transponder (PIT) tag surveys to monitor this behavior in the Del Norte salamander (Plethodon elongatus), a small plethodontid native to northwestern California and southwestern Oregon. Within its range, a climatic gradient exists in which coastal areas experience milder temperatures and high precipitation, while inland areas tend to have colder winters, hotter summers, and lower precipitation. By monitoring the activity patterns of this species in inland and coastal areas, …


Expanding American Indian Land Stewardship: An Environmental Solution For A Country In Crisis, Haley Edmonds Jan 2022

Expanding American Indian Land Stewardship: An Environmental Solution For A Country In Crisis, Haley Edmonds

Law Student Publications

Land is the central foundation around which all life is formed. Therefore, societies must have a stable connection with the land in order to be structurally sound. If this connection is weak or inflexible, every building-block of civilization laid on top of it will inevitably crumble. Some societies have established stable relationships with the land by working around and responding to nature’s rhythms in order to satisfy their needs. Whereas other societies have ignored nature’s intricacies and instead have tried to strong-arm nature into yielding to their whims. These two diametrically opposed approaches to conceiving of humans’ relationship with the …


Temporal Buffer Zones: The Constitutional Case For Regulating Political Speech Immediately Prior To Elections, Kiel Brennan-Marquez, Douglas M. Spencer Jan 2022

Temporal Buffer Zones: The Constitutional Case For Regulating Political Speech Immediately Prior To Elections, Kiel Brennan-Marquez, Douglas M. Spencer

Publications

The First Amendment forbids most limits on political speech, but it permits buffer zones around polling stations on Election Day. This exception to the deregulatory thrust of election speech doctrine is striking, and strikingly under-theorized. In what follows, we excavate the core principle that underpins the buffer zone exception-decisional solemnity-and we argue that, properly understood, the same principle justifies the use of temporal buffer zones: stricter-than-normal regulations on certain types of political speech in the immediate vicinity of an election. Voting, we argue, is an act different in kind from the deliberation that precedes it. Accordingly, governmental efforts to ensure …


Consequences Of Thermal Plasticity For Hypoxic Performance In Coastal Amphipods, Michael Collins, Manuela Truebano, John I. Spicer Jan 2022

Consequences Of Thermal Plasticity For Hypoxic Performance In Coastal Amphipods, Michael Collins, Manuela Truebano, John I. Spicer

School of Biological and Marine Sciences

No abstract provided.


Responding To Eruptive Transitions During The 2020–2021 Eruption Of La Soufrière Volcano, St. Vincent, E. P. Joseph, M. Camejo-Harry, T. Christopher, R. Contreras-Arratia, S. Edwards, O. Graham, M. Johnson, A. Juman, J. L. Latchman, L. Lynch, V. L. Miller, I. Papadopoulos, K. Pascal, R. Robertson, G. A. Ryan, A. Stinton, R. Grandin, I. Hamling, M. J. Jo, J. Barclay, P. Cole, B. V. Davies, R. S.J. Sparks Jan 2022

Responding To Eruptive Transitions During The 2020–2021 Eruption Of La Soufrière Volcano, St. Vincent, E. P. Joseph, M. Camejo-Harry, T. Christopher, R. Contreras-Arratia, S. Edwards, O. Graham, M. Johnson, A. Juman, J. L. Latchman, L. Lynch, V. L. Miller, I. Papadopoulos, K. Pascal, R. Robertson, G. A. Ryan, A. Stinton, R. Grandin, I. Hamling, M. J. Jo, J. Barclay, P. Cole, B. V. Davies, R. S.J. Sparks

School of Geography, Earth and Environmental Sciences

Abstract: A critical challenge during volcanic emergencies is responding to rapid changes in eruptive behaviour. Actionable advice, essential in times of rising uncertainty, demands the rapid synthesis and communication of multiple datasets with prognoses. The 2020–2021 eruption of La Soufrière volcano exemplifies these challenges: a series of explosions from 9–22 April 2021 was preceded by three months of effusive activity, which commenced with a remarkably low level of detected unrest. Here we show how the development of an evolving conceptual model, and the expression of uncertainties via both elicitation and scenarios associated with this model, were key to anticipating this …


Framing And Contesting Unauthorized Work, Angela D. Morrison Jan 2022

Framing And Contesting Unauthorized Work, Angela D. Morrison

Faculty Scholarship

Unauthorized workers face precarity in the workplace and the threat of forced expulsion from their communities. Some of the reasons for that precarity result from how the law frames unauthorized workers. The law views unauthorized workers as lacking full human or civil rights, as “unauthorized,” to the exclusion of their other identities. The legal system also creates a binary that views unauthorized workers as either criminals who are complicit in their exploitation or passive victims for employers to exploit. This Article draws on social movement literature to theorize the processes that result in this framing and to explore how immigrant …


2021 Annual Report, Bank Of Mongolia (Mongolbank) Jan 2022

2021 Annual Report, Bank Of Mongolia (Mongolbank)

Documents

No abstract provided.


Influences Of Disrupted Circadian Rhythms On Stroke Outcome, Jennifer A. Liu Jan 2022

Influences Of Disrupted Circadian Rhythms On Stroke Outcome, Jennifer A. Liu

Graduate Theses, Dissertations, and Problem Reports (ETD)

The circadian system is composed of a subset of temporal oscillators that function through a transcriptional and post-translational molecular and functional negative feedback loop cycling approximately every 24 hours. The central clock located in the suprachiasmatic nucleus is responsible for entrainment using light as the key timekeeper (zeitgeber); it is responsible for synchronizing and optimizing physiological behavior and function to the environment. Exogenous information, such as day length and light-dark cycles, provide critical temporal cues for adjusting to environmental conditions. Proper alignment to natural light dark cycles and circadian rhythms is optimal for vital health, fitness, and survival in organisms. …


Investigating The Interplay Of The Immune System, Skin Barrier, And Microbiome Following Dermal Exposure To Triclosan, Rachel Baur Jan 2022

Investigating The Interplay Of The Immune System, Skin Barrier, And Microbiome Following Dermal Exposure To Triclosan, Rachel Baur

Graduate Theses, Dissertations, and Problem Reports (ETD)

Triclosan is an antimicrobial chemical used in healthcare products that are applied to the skin. However, exposure to triclosan has been positively associated with food allergy, aeroallergy, and asthma severity in humans. In mice, dermal triclosan exposure, although not directly sensitizing, has been shown to augment the allergic response in a model of asthma. Furthermore, exposure to triclosan on mouse skin has been demonstrated to be immunomodulatory through the activity of thymic stromal lymphopoietin and S100 calcium-binding protein A8. The skin barrier and microbiome are known to interact with the immune system and disruptions in barrier integrity and the microbiome …


Integration Of Fisheries Ecology With The Assessment Of Microplastic Consumption In Black Bass In The Upper Ohio River Drainage, Kaylyn Zipp Jan 2022

Integration Of Fisheries Ecology With The Assessment Of Microplastic Consumption In Black Bass In The Upper Ohio River Drainage, Kaylyn Zipp

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis explores the dynamics of microplastic consumption of black bass (smallmouth, Micropterus salmoides, largemouth, M. dolomieu, and spotted bass, M. punctulatus) in the Monongahela and Kanawha River and explores dietary characteristics in the Ohio, Monongahela, and Kanawha River. The first chapter serves as an introduction and synthesis of microplastic consumption, fisheries ecology, and regional information. The second chapter quantifies microplastic consumption in the Monongahela River and explores spatial variation within and between species by pool and seasonal effects. The third chapter consists of exploratory Quasi Poisson modeling of total microplastics in the Point Marion pool, Monongahela River, WV using …


Evaluating Muskellunge (Esox Masquinongy) Catch-And-Release Mortality At Elevated Summer Water Temperature, Ian Taylor Booth Jan 2022

Evaluating Muskellunge (Esox Masquinongy) Catch-And-Release Mortality At Elevated Summer Water Temperature, Ian Taylor Booth

Graduate Theses, Dissertations, and Problem Reports (ETD)

Angling for Muskellunge (Esox masquinongy) has become widespread and increasingly popular throughout the fish’s range. Current management strategies for Muskellunge include high minimum harvest lengths (>1016mm), closed seasons, and catch-and-release regulations. Due to these strategies and angler sentiments, up to 97% of Muskellunge caught today are released by anglers assuming they will live and be caught again in the future. Previous research on catchand-release mortality in Muskellunge has suggested relatively low mortality rates (0%-5%). However, these studies were all conducted within the fish’s thermal optimum and generally at water temperatures25°C during the summer months, representing a need to evaluate …


Integration Of Spectroscopic And Mass Spectrometric Tools For The Analysis Of Novel Psychoactive Substances In Forensic And Toxicology Applications, Travon Cooman Jan 2022

Integration Of Spectroscopic And Mass Spectrometric Tools For The Analysis Of Novel Psychoactive Substances In Forensic And Toxicology Applications, Travon Cooman

Graduate Theses, Dissertations, and Problem Reports (ETD)

Analytical methods aiming for the detection of novel psychoactive substances are continuously revised due to their utility in the seized drug and toxicology realms. One method frequently employed for the preliminary identification of illicit materials is portable Raman spectroscopy. Even when a substance in possession of an offender is identified, conclusive evidence that it may have been consumed requires additional confirmatory work and further toxicological evaluation of a biological specimen. Many times, the substance consumed may not be detected in the analyzed specimen due to its extensive metabolism. It is therefore challenging to rule out the identity of the drug …


Performance Of Sensor Fusion For Vehicular Applications, Nikola Janevski Jan 2022

Performance Of Sensor Fusion For Vehicular Applications, Nikola Janevski

Graduate Theses, Dissertations, and Problem Reports (ETD)

Sensor fusion is a key system in Advanced Driver Assistance Systems, ADAS. The perfor-
mance of the sensor fusion depends on many factors such as the sensors used, the kinematic
model used in the Extended Kalman Filter, EKF, the motion of the vehicles, the type of
road, the density of vehicles, and the gating methods. The interactions between parameters
and the extent to which individual parameters contribute to the overall accuracy of a sensor
fusion system can be difficult to assess.
In this study, a full-factorial experimental evaluation of a sensor fusion system based
on a real vehicle was performed. …


Population Characteristics Of Three Black Bass Species In The Upper Ohio River Drainage, Levi Foster Brown Jan 2022

Population Characteristics Of Three Black Bass Species In The Upper Ohio River Drainage, Levi Foster Brown

Graduate Theses, Dissertations, and Problem Reports (ETD)

In West Virginia, species of black bass are economically and ecologically important and support popular fisheries. In the state’s large, navigable river systems, recent information suggests that anglers consider these fisheries diminished relative to their historic stocks. This study sought to describe the population characteristics of Largemouth, Smallmouth, and Spotted Bass in the upper Ohio River drainage and evaluate possible management actions. Low relative abundances coupled with poor growth estimates for Largemouth and Spotted Bass suggests that a suite of environmental and anthropogenic factors may be reducing the quality of their recreational fisheries. Conversely, demographic estimates produced for Smallmouth Bass …


Landmark Enforcement And Principal Component Analysis For Improving Gan-Based Morphing, Samuel W. Price Jan 2022

Landmark Enforcement And Principal Component Analysis For Improving Gan-Based Morphing, Samuel W. Price

Graduate Theses, Dissertations, and Problem Reports (ETD)

Facial Recognition Systems (FRSs) are a key target for adversaries determined to circumvent security checkpoints. Morph images threaten FRS by presenting as multiple individuals, allowing an adversary to swap identities with another subject. Although morph generation using generative adversarial networks (GANs) results in high-quality morphs without possessing the spatial artifacts caused by landmarkbased methods, there is an apparent loss in identity with standard GAN-based morphing methods. In this thesis, we examine landmark-based and GAN-based morphing methods to fuse the advantages of both methodologies. We propose a novel StyleGAN2 morph generation technique by introducing a landmark enforcement method. Considering this method, …


Clitic Doubling: The Case Of Nariño Andean Spanish, Jessica Paola Jurado Eraso Jan 2022

Clitic Doubling: The Case Of Nariño Andean Spanish, Jessica Paola Jurado Eraso

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis examines the behavior of clitic doubling in Nariñense, a little-studied Andean Spanish variety spoken in the southwest of Colombia, and compares it to well-studied varieties such as standard Peninsular, Rioplatense, and other Andean Spanish varieties. Its aim is to present novel data about clitic doubling in order to shed more light into the extensive literature about this phenomenon in Spanish. Through spontaneous speech recordings obtained from thirty native speakers of Nariñense, 133 sentences involving clitic doubling were analyzed. Features such as agreement matching between the clitic and the doubled NP, use of the preposition a to introduce the …


Frayed Connections: How Long-Term Nitrogen Additions Disrupt Plant-Soil Interactions And The Carbon Cycle Of A Temperate Forest, Brooke A. Eastman Jan 2022

Frayed Connections: How Long-Term Nitrogen Additions Disrupt Plant-Soil Interactions And The Carbon Cycle Of A Temperate Forest, Brooke A. Eastman

Graduate Theses, Dissertations, and Problem Reports (ETD)

Forests are expected to mitigate some of the negative effects of climate change by sequestering anthropogenic carbon (C) from the atmosphere, but the degree to which they drawn down C will depend on the availability of key nutrients, such as nitrogen (N). There is a fair amount of uncertainty in the future of the forest C sink, mostly owing to the fate of soil organic matter (SOM) and soil heterotrophic respiration to future conditions. In N limited systems, plants allocate a significant amount of their photosynthate belowground for the acquisition of nutrients, but under conditions of chronic N deposition, plants …


Fasciotomies, Gabriel Bass Jan 2022

Fasciotomies, Gabriel Bass

Graduate Theses, Dissertations, and Problem Reports (ETD)

This collection of poems follows the disjointed and never complete trajectory of personal recovery from trauma and alcoholism. The poems and their arrangement trouble the notion of a person ever being fixed, even as they make progress toward a better version of themselves. The collection illustrates how the past can impose itself on the present, creating dissonance and complicating the speaker’s understanding of time and recovery.


Amelioration Of Mitochondrial Bioenergetic Dysfunction In Diabetes Mellitus: Delving Into Specialized And Non-Specific Therapeutics For The Ailing Heart, Andrya Jean Durr Jan 2022

Amelioration Of Mitochondrial Bioenergetic Dysfunction In Diabetes Mellitus: Delving Into Specialized And Non-Specific Therapeutics For The Ailing Heart, Andrya Jean Durr

Graduate Theses, Dissertations, and Problem Reports (ETD)

Morbidity and mortality of the diabetic population is influenced by many confounding factors, but cardiovascular disease (CVD), remains the leading cause of death. Mitochondrial dysfunction is central in the development of cardiac contractile dysfunction, with decreased mitochondrial bioenergetic function, increased dependence on free fatty acid utilization, and a decrease in glucose utilization having been shown to contribute to contractile dysfunction. Strategies targeting the amelioration of mitochondrial bioenergetic function are attractive for limiting diabetes-induced heart failure, and preserving health-span. The goals of this dissertation were to assess two mitochondrial-centric approaches for the amelioration of mitochondrial and cardiac contractile dysfunction in diabetes …


Incidence Of Cancer, Depression, And Economic Burden Of Prescription Nsaids Among Older Adults With Osteoarthritis: Statistical And Machine Learning Approaches, Nazneen Fatima Mohammed Umer Shaikh Jan 2022

Incidence Of Cancer, Depression, And Economic Burden Of Prescription Nsaids Among Older Adults With Osteoarthritis: Statistical And Machine Learning Approaches, Nazneen Fatima Mohammed Umer Shaikh

Graduate Theses, Dissertations, and Problem Reports (ETD)

Understanding the role of chronic inflammation among older adults is critical because of its implications on chronic inflammatory conditions as well as its interaction with anti-inflammatory medications. Osteoarthritis (OA) is a heterogeneous multi-faceted joint disease with multi-tissue involvement of varying severity, and increasing evidence demonstrates a key role of chronic inflammation in its pathogenesis. Approximately 30 million adults in the United States have OA, and it is reported that a large proportion (43%) of them are older than 65 years. OA is typically treated using non-steroidal anti-inflammatory drugs (NSAIDs) for minimizing pain and reducing inflammation. NSAIDs have consistently shown clinically …


Navigating Abrupt Shifts In Contextual Discourses During A Pandemic And Lack Of Mentorship: A Preservice Teacher’S Journey Developing Critical Pedagogical Discourses, Casey L. King Jan 2022

Navigating Abrupt Shifts In Contextual Discourses During A Pandemic And Lack Of Mentorship: A Preservice Teacher’S Journey Developing Critical Pedagogical Discourses, Casey L. King

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study is centered on one English language arts (ELA) preservice teacher’s development of her critical pedagogical discourses (CPD) with the contextual discourses of a school placement for preservice teaching and later shift to a full-time teacher before the placement was complete during a pandemic and in the midst of implementing online learning. Data is drawn from a 4-month interpretive qualitative case study that included classroom observations and semi-structured interviews. The objective for this study included how a preservice teacher uses their beliefs and identity about instruction amid changing contextual discourses in a pandemic and with a lack of mentorship. …


Utilizing The K18-Hace2 Mouse Model To Develop Protective Covid-19 Vaccines, Ting Y. Wong Jan 2022

Utilizing The K18-Hace2 Mouse Model To Develop Protective Covid-19 Vaccines, Ting Y. Wong

Graduate Theses, Dissertations, and Problem Reports (ETD)

The ongoing Coronavirus Disease 2019 (COVID-19) pandemic is caused by the respiratory virus Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Similar to other respiratory viruses, SARS-CoV-2 is transmitted through inhalation of respiratory droplets and aerosols from infected individuals. Once inhaled, SARS-CoV-2 utilizes the receptor binding domain (RBD) on the spike protein to bind to human Angiotensin Converting Enzyme 2 (hACE2) receptor to gain entrance into host cells to begin viral replication. SARS-CoV-2 infection can result in mild to severe cases of COVID-19 ranging from asymptomatic infections, cold or flu like symptoms to respiratory failure. The onset of the pandemic in …


Associations Between Self-Reported Awe And Heart Rate, Laura E. Bernstein Jan 2022

Associations Between Self-Reported Awe And Heart Rate, Laura E. Bernstein

Graduate Theses, Dissertations, and Problem Reports (ETD)

Fredrickson’s (1998, 2013) broaden and build theory states that positive emotions can expand our social and cognitive awareness and provide health benefits. Some positive emotions, such as awe, may operate differently. We sought to understand how subjective reports of awe, induced through videos, correlate with HR. We know that HR tends to decrease with age (Umetani et al., 1998), individuals have less physiological reactivity as they age (Blanchard-Fields, 2007), and older adults report more positive emotions than negative emotions (Mroczek & Kolarz, 1998). Given these findings, we were interested in understanding whether there were age differences in self-reported awe and …


Deep Radio Observations And The Role Of The Cosmic Web In Galaxy Evolution, Nicholas M. Luber Jan 2022

Deep Radio Observations And The Role Of The Cosmic Web In Galaxy Evolution, Nicholas M. Luber

Graduate Theses, Dissertations, and Problem Reports (ETD)

A current open question in the evolution of galaxies, is what are the physical mechanisms that cut off galaxies from their primordial gas reservoirs, resulting in the end of their star-formation capabilities? Recent observational programs have shown that the properties of galaxies show dependencies on their placement within the large-scale structure (LSS) of the universe. These observations have motivated recent developments in theoretical work that have shown how a galaxy's interaction with the LSS may impact its connection to primordial gas supply, and ability to continue to accrete gas, the fundamental ingredient in star-formation.

In order to investigate the role …


Transitions Between The Steps Of Group Iic Intron Forward And Reverse Splicing And Integration Into Dna, Claire Mae Smathers Jan 2022

Transitions Between The Steps Of Group Iic Intron Forward And Reverse Splicing And Integration Into Dna, Claire Mae Smathers

Graduate Theses, Dissertations, and Problem Reports (ETD)

Group II introns are ancient ribozymes capable of self-excision and mobility into new genomic locations. As the ancestors of both the eukaryotic spliceosome and eukaryotic retroelements, these simple RNA machines serve as excellent models for understanding the mechanisms of both gene splicing and retroelement activity in eukaryotes. Although group II introns have been studied for decades, knowledge of the most unique and arguably evolutionarily relevant class of group II introns, IIC, is limited. Our knowledge is especially limited in terms of understanding how IIC introns mediate the transition between the two transesterification steps of forward splicing and reverse splicing into …


Bitter Sweet, Hanna M. Kesty Jan 2022

Bitter Sweet, Hanna M. Kesty

Graduate Theses, Dissertations, and Problem Reports (ETD)

This written document is the accompanying thesis for my Master of Fine Arts Exhibition, Bitter Sweet. The exhibition featured traditional framed prints with sculptural accents that reveal brutally honest negative personal experiences, interactions, and emotions, paired with delicately cute aesthetics. My work embodies the necessity of personal artistic expression to process years of emotional repression. The prints and sculptures in the exhibition focus around a collection of insults and harsh comments coupled with feelings of loneliness and isolation. I allow personal vulnerability to show, to reinforce that these moments have molded and shaped who I am and will continue to …


Detecting Adverse Drug Events Using A Deep Neural Network Model, Saminur Islam Jan 2022

Detecting Adverse Drug Events Using A Deep Neural Network Model, Saminur Islam

Graduate Theses, Dissertations, and Problem Reports (ETD)

Adverse drug events represent a key challenge in public health, especially with respect to drug safety profiling and drug surveillance. Drug-drug interactions represent one of the most popular types of adverse drug events. Most computational approaches to this problem have used different types of drug-related information utilizing different types of machine learning algorithms to predict potential interactions between drugs. In this work, our focus is on the use of genetic information about the drugs, in particular, the protein sequence and protein structure of drug protein targets to predict potential interactions between drugs. We collected information on drug-drug interactions (DDIs) from …