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Standardization And Dna Barcoding Of Cannabis In Thailand And Pharmacological Properties Of Cannabis-Based Thai Traditional Medicine Formula Extract (Kealomkeasan), Kanittha Nakkliang

Chulalongkorn University Theses and Dissertations (Chula ETD)

Cannabis sativa L. subsp. Indica (Cannabaceae) has been used as a medicinal plant in various aspects. C. sativa has been part of Thai medicine for more than three centuries and its Ingredients in herbal medicine recipe. Kealomkeasan (KLKS) remedy is one of the Thai traditional medicines, consists of seven plants with an unequal part by weight (1:2:3:4:5:20:40) as follows: Cuminum cyminum L. fruits, Nigella sativa L. seeds, Foeniculum vulgare Miller fruits, Zingiber officinale Roscoe rhizomes, Plumbago indica L. roots, Cannabis sativa L. leaves and Piper nigrum L. seeds for relief of muscle pain and anti-inflammation. Recently, medical cannabis was officially …

Therapeutic Efficacy Of Subconjunctival Injectionof Canine Adipose-Derived Mesenchymal Stem Cells On Canine Spontaneous Chronic Corneal Epithelial Defect, Pechchalee Kengkla

Chulalongkorn University Theses and Dissertations (Chula ETD)

Spontaneous chronic corneal epithelial defects (SCCEDs) are important corneal injuries in dogs. Canine adipose-derived mesenchymal stem cells (cAD-MSCs) was used for treatment of various types of corneal ulcers in dogs. This study aimed to evaluate clinical outcomes and concentrations of tear fluid cytokine after subconjunctival injection of cAD-MSCs in canine SCCEDs. 9 canine SCCEDs eyes previously treated by debridement twice were included into this study. All eyes received a single subconjunctival injection of 1x106 cAD-MSCs. Ophthalmic examinations were undergone at day 7, 14 and 21 after treatment. Photographs of the cornea were taken to assess corneal epithelial defect, neovascularization and …

Production Of Pd-L1 Immune Checkpoint Inhibitor In Nicotiana Benthamiana, Thareeya Phetphoung

Chulalongkorn University Theses and Dissertations (Chula ETD)

Immune checkpoint antibodies disrupt the binding of receptor-ligand pairs which regulate immune response in cancer treatment. PD-1/PD-L1 pathway has become one target of the cancer immunotherapy approaches. Atezolizumab, the first FDA-approved antibody to PD-L1 in the treatment of metastatic urothelial, non-small cell lung, small cell lung, and hepatocellular cancers, is expressed in Chinese Hamster Ovary (CHO) cell lines with several limitations, i.e., high costs of production, limited-capacity yields, and pathogen risks. To overcome these drawbacks, the transient expression in Nicotiana benthamiana leaves, which provide expandable scalability and inexpensive costs, was investigated by co-infiltration of Agrobacterium tumefaciens GV3101 cultures harboring Atezolizumab …

Development Of A Animal Assisted Therapy Intervention Manual And Screening Tool For The Pediatric Population, Moira O'Keefe

Occupational Therapy Doctoral Capstones

The doctoral capstone project aims to 1) create a pediatric animal assisted therapy intervention manual and 2) screening tool to promote appropriate and diverse usage of AAT for increased goal achievement. The intervention manual and screening tool serves as an evidence-based educational resource and tool that therapists can use to advocate for occupational therapists' role within animal assisted therapy and fill a gap within the population.

Deciphering The Role Of Mitochondrial Physiology And Thermal Acclimation In Shaping Whole Organismal Performance Of An Invasive Forest Pest, Essa Alrashdi

Masters Theses

Environmental factors such as temperature are substantial determinants of the spongy moth, L. dispar, distribution, reproduction, and growth. Accumulating energy reserves at the larval stage is particularly important to L. dispar, since the larvae metamorphose into a fully-grown, non-feeding adult. As non-feeding adults, the energy balance of the pupae must be adequate, to ensure enough energy reserves for adult dispersal, egg maturation and overall persistence of the species in the region. At this stage, environmental temperature also determines daily metabolic demands, and the overall cost of sustaining ecologically relevant activities. Various hypotheses describing a mismatched growth and metabolic …

"Comic"Ally Calling For Cultural Competency: Using Graphic Narratives To Teach Social Justice In The Writing Classroom, Travis Moody

Masters Theses

No abstract provided.

Comparison Of Bigheaded Carp Reproduction In Tributaries Of The Illinois And Wabash Rivers, David J. Yff

Masters Theses

Understanding environmental conditions that support bigheaded carp (Hypophthalmichthys sp.) reproduction in tributary rivers provides key predictions of their invasion throughout the United States. Past research, primarily in larger order rivers, identified factors such as discharge, temperature, and turbidity as main environmental drivers of bigheaded carp reproduction. I used the variable hydrologic conditions between the Illinois and Wabash Rivers to compare environmental conditions between tributaries of each basin, determine which conditions influence bigheaded carp reproduction in tributaries, and predict tributaries likely to support bigheaded carp reproduction. Three tributaries of the Illinois and Wabash Rivers were sampled for ichthyoplankton from …

Differences In The Growth And Bioenergetics Between Centrarchids In A Midwestern Power Plant Lake, Kyle Joseph Rempe

Masters Theses

Black Crappie Pomoxis nigromaculatus and Bluegill Lepomis macrochirus are popular sportfishes that co-occur in similar bodies of water throughout most of the Central and Eastern United States but have distinct thermal physiologies. L. macrochirus is often found in warmer regions of freshwater reservoirs, where P. nigromaculatus tends to exploit cooler regions, especially in power plant cooling reservoirs. The coal-fired Coffeen Power Station ceased energy production in October 2019, providing an ideal scenario to study the organismal effects of the sudden shift in thermal regime. Previous studies showed that P. nigromaculatus inhabited the less thermally-impacted areas of Coffeen Lake, whereas L. …

Oregon State Rank Assessment For Larch Mountain Salamander (Plethodon Larselli), Eleanor P. Gaines

Institute for Natural Resources Publications

Oregon state conservation status assessment for Larch Mountain salamander (Plethodon larselli) using NatureServe methodology, 2022.

Differential Progression Of Unhealthy Diet-Induced Hepatocellular Carcinoma In Obese And Non-Obese Mice, Emma Hymel, Elizabeth M. Vlock, Kurt W. Fisher, Paraskevi A. Farazi

Journal Articles: Epidemiology

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) ranks first among liver diseases in Western countries. NAFLD is typically associated with obesity and diabetes, however it also develops in lean individuals without metabolic syndrome. The prevalence of lean NAFLD is 7 percent in the U.S. and 25-30 percent in some Asian countries. NAFLD starts with excess liver fat accumulation (NAFL), progresses to nonalcoholic steatohepatitis (NASH), cirrhosis and hepatocellular carcinoma (HCC). The pathogenesis of lean NASH-HCC and how it differs from obese NASH-HCC is not well understood.

METHODS: In this work, we generated a mouse model of lean and obese NASH-HCC using a …

Willingness To Pay For Mangroves’ Coastal Protection: A Case Study In Santo Angel, Calauag, Quezon, Philippines, Wesley Gagarin, Decibel F. Eslava, Rico Ancog, Cristino L. Tiburan Jr, Noelynna Ramos

Forest and Society

The mangroves in Santo Angel in the municipality of Calauag, Quezon Province in the Philippines, provide a wide array of ecological services that range from provisioning of resources and habitat to various floral and faunal species to regulating services including coastal protection. Coastal protection from mangroves is needed by the local community as Santo Angel is susceptible to typhoons and storm surges. However, the mangrove’s ability to provide coastal defense has considerably declined in the past decades due to overexploitation. Using the double-bounded dichotomous choice contingent valuation method, the willingness to pay (WTP) of the local community for a hypothetical …

Loss Of Smad4 Is Associated With Poor Tumor Immunogenicity And Reduced Pd-L1 Expression In Pancreatic Cancer, Daniel R. Principe, Patrick W. Underwood, Sandeep Kumar, Kaytlin E. Timbers, Regina M. Koch, Jose G. Trevino, Hidayatullah G. Munshi, Ajay Rana

Surgery Publications

Transforming Growth Factor β (TGFβ) is a key mediator of immune evasion in pancreatic ductal adenocarcinoma (PDAC), and the addition of TGFβ inhibitors in select immunotherapy regimens shows early promise. Though the TGFβ target SMAD4 is deleted in approximately 55% of PDAC tumors, the effects of SMAD4 loss on tumor immunity have yet to be fully explored. Using a combination of genomic databases and PDAC specimens, we found that tumors with loss of SMAD4 have a comparatively poor T-cell infiltrate. SMAD4 loss was also associated with a reduction in several chemokines with known roles in T-cell recruitment, which was recapitulated …

Should "Morphed" Child Pornography Fall Under The Protection Of The First Amendment's Free Speech Clause?, Carliette Sierralta

Nova Law Review

No abstract provided.

Iguanodons Throughout The Ages (Illustrations), Patrick Estell

The Synapse: Intercollegiate science magazine

No abstract provided.

[Crn 37945] Philosophy 103, Alina N. Feld

Open Educational Resources

This is a syllabus for PHIL 103 a Zero-Cost Course, using an OER textbook.

Acute Ethanol-Induced Liver Injury Is Prevented By Betaine Administration, Madan Kumar Arumugam, Srinivas Chava, Sathish Kumar Perumal, Matthew C. Paal, Karuna Rasineni, Murali Ganesan, Terrence Donohue, Natalia A. Osna, Kusum K. Kharbanda

Journal Articles: Internal Medicine

Binge drinking is the most common form of excessive alcohol use. Repeated episodes of binge drinking cause multiple organ injuries, including liver damage. We previously demonstrated that chronic ethanol administration causes a decline in the intrahepatic ratio of S-adenosylmethionine (SAM) to S-adenosylhomocysteine (SAH). This decline causes impairments in essential methylation reactions that result in alcohol-induced fatty liver (steatosis) and other features of alcohol-associated liver disease (ALD). Co-treatment with betaine during chronic ethanol feeding, normalizes hepatocellular SAM:SAH ratio and alleviates many features of liver damage including steatosis. Here, we sought to examine whether betaine treatment similarly protects against liver injury in …

Clouded Precedent: Tandon V. Newsom And Its Implications For The Shadow Docket, Alexander Gouzoules

Faculty Publications

The Supreme Court’s “shadow docket”—the decisions issued outside its procedures for deciding cases on the merits—has drawn increasing attention and criticism from scholars, commentators, and elected representatives. Shadow docket decisions have been criticized on the grounds that they are made without the benefit of full briefing and argument, and because their abbreviated, per curiam opinions can be difficult for lower courts to interpret.

A spate of shadow docket decisions in the context of free-exercise challenges to COVID-19 public health orders culminated in Tandon v. Newsom, a potentially groundbreaking decision that may upend longstanding doctrines governing claims brought under the Free …

Food, Freedom, Fairness, And The Family Farm, Robin M. Rotman, Sophie Mendelson

Faculty Publications

The concept of the “family farm” holds powerful sway within the American narrative, embodying both nostalgia for an imagined past and anxiety for a future perceived to be under threat. Since the founding of the United States, this cultural ideal has been invoked in support of a rosy vision of agrarian democracy while obscuring the ways in which the U.S. Department of Agriculture’s codified definition of “family farm” has unfairly aggregated advantages for the benefit of a particular kind of family (nuclear) and farmer (white, male, straight). At the same time, consumers are misled by an under-interrogated conflation of family …

Avian Eggshell Coloration Predicts Shell-Matrix Protoporphyrin Content, Charles F. Thompson, Kara E. Hodges, Nathan T. Mortimer, Alysia D. Vrailas-Mortimer, Scott K. Sakaluk, Mark E. Hauber

Faculty Publications – Biological Sciences

Avian eggshell pigmentation may provide information about a female’s physiological condition, in particular her state of oxidative balance. Previously we found that female House Wrens (Troglodytes aedon Vieillot, 1809) with lighter, less-maculated, and redder ground-colored shells were older and produced heavier offspring than females laying more-maculated and browner eggs. The strong pro-oxidant protoporphyrin is responsible for this species’ eggshell pigmentation, so differences in pigmentary coloration may be related to eggshell protoporphyrin content and reflect female oxidative balance and condition during egg formation. Therefore, we tested the assumption that egg-surface coloration is related to the amount of protoporphyrin in the …

Biomarkers Of Inflammation And Oxidative Stress In The Prediction And Management Of Acute Coronary Syndrome, Udaya Ralapanawa, Sivakanesan R

Health Sciences

The assessment of patients presenting with chest pain or symptoms indicative of cardiac ischemia remains a diagnostic challenge. Many types of research have focused on the search for ideal biological markers for the rapid detection of cardiac cell injuries. Markers of inflammation and oxidative stress are the way forward. At present, the biomarker most widely used for diagnosing acute coronary syndrome is cardiac troponin though it has some limitations. Apart from cardiac troponin, several other biomarkers, especially inflammation and oxidative stress markers in acute coronary syndrome, have been investigated. However, most of them still require validation in further studies. As …

Spring Break In Chernobyl: Urbex, Apocalypse, And Materiality In Writing Classrooms, K Shannon Howard

The Journal of the Assembly for Expanded Perspectives on Learning

The practice of urban exploration, or urbex—an activity in which we confront and document landscapes of ruin and make meaning from them—acts as a focal point through which students may investigate and write about the world surrounding them by gaining new perspectives of physical spaces and objects that often go ignored in daily living. More importantly, urbex inspires writing that responds to existing problems in our world (resource scarcity, lack of sustainability, and environmental trauma) while also helping students to conceptualize a better one.

South Dakota State University Graduate Catalog 2022-2023, South Dakota State University

South Dakota State University Catalogs and Bulletins: 1935 to present

No abstract provided.

The Chironian 2021-2022, New York Medical College

The Chironian

The Chironian is distributed to a readership of 16,000 faculty, alumni and employees of New York Medical College, government and community leaders, affiliated hospitals and selected media. Each issue is carefully crafted to provide a balance of articles on cutting-edge research, personality profiles, student accomplishments and alumni news from all five schools on the NYMC campus. Inquiries can be sent to [email protected].

Admissions Publications 2022-2023, University Of Minnesota Morris, Admissions

Miscellaneous Campus Publications

Admissions publications for 2022-2023.

-Thrive

-An Investment That Counts

-People Place Purpose Find Yours At Morris

The Honors Beacon, Issue 20, 2021-2022, Honors Program At Minnesota State University, Mankato

Honors Beacon

2021-2022 newsletter of the Honors Program at Minnesota State University, Mankato.

Biological Sciences Associate Degree Annual Program Outcomes Assessments, 2021-22, Lake Campus, Wright State University

Annual Program Outcomes Assessments - All

This report reviews Wright State University's Biological Sciences Associate Degree program for the 2021-2022 academic year.

Maud Gordon Holmes Arboretum List Of Tree Species, Chloe Mokadam

Maud Gordon Holmes Arboretum database

Maud Gordon Holmes Arboretum database of Tree Species.

From Logic To Realism To Brighter Future For Humanity, Victor Christianto, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

This collection of published papers at International Journal of Neutrosophic Science actually began with just a simple request by Dr. Broumi Said, the editor of IJNS, to us, to submit an article for his new journal. Then we submitted a series of new articles discussing various applications of Neutrosophic Logic, a new kind of logic as developed by one of us (FS). We explore a wide range of subject, from Godel’s incompleteness theorem, to possible technocalypse and neutro-futurology, and also additional sections. Hopefully you will find these articles interesting for better understanding of nature.

Artificial Intelligence And Trade Secret Law, 21 Uic Rev. Intell. Prop. L. 252 (2022), Gregory Gerard Greer

UIC Review of Intellectual Property Law

No abstract provided.

Myths And Clichés: The Doctrinal Myopia Of Publicity Right, 22 Uic Rev. Intell. Prop. L. 50 (2022), Mira Moldawer

UIC Review of Intellectual Property Law

No abstract provided.