Digital Commons Network^™

Proteomic Signatures Of Myeloid Derived Suppressor Cells From Liver And Lung Metastases Reveal Functional Divergence And Potential Therapeutic Targets, Nicholas A. Dasilva, Benjamin J. Barlock, Prajna Guha, Chandra C. Ghosh, Catherine E. Trebino, Jodi L. Camberg, Steven C. Katz, David C. Rowley

Cell and Molecular Biology Faculty Publications

Myeloid-derived suppressor cells (MDSCs) promote immunosuppressive activities in the tumor microenvironment (TME), resulting in increased tumor burden and diminishing the anti-tumor response of immunotherapies. While primary and metastatic tumors are typically the focal points of therapeutic development, the immune cells of the TME are differentially programmed by the tissue of the metastatic site. In particular, MDSCs are programmed uniquely within different organs in the context of tumor progression. Given that MDSC plasticity is shaped by the surrounding environment, the proteomes of MDSCs from different metastatic sites are hypothesized to be unique. A bottom-up proteomics approach using sequential window acquisition of …

Hsva: Hierarchical Semantic-Visual Adaptation For Zero-Shot Learning, Shiming Chen, Guo Sen Xie, Yang Liu, Qinmu Peng, Baigui Sun, Hao Li, Xinge You, Ling Shao

Machine Learning Faculty Publications

Zero-shot learning (ZSL) tackles the unseen class recognition problem, transferring semantic knowledge from seen classes to unseen ones. Typically, to guarantee desirable knowledge transfer, a common (latent) space is adopted for associating the visual and semantic domains in ZSL. However, existing common space learning methods align the semantic and visual domains by merely mitigating distribution disagreement through one-step adaptation. This strategy is usually ineffective due to the heterogeneous nature of the feature representations in the two domains, which intrinsically contain both distribution and structure variations. To address this and advance ZSL, we propose a novel hierarchical semantic-visual adaptation (HSVA) framework. …

Q & A With Cole: 2021 Festival Of Lights, Cole Ray

GWU-Today

Dr. Josh Cheney is the assistant professor of music and the director of choral activities and coordinator of worship leadership in the Gardner-Webb Department of Music. I sat down with him to learn more about the Festival of Lights and what to expect this year. The Festival Of Lights is Dec. 2 at 7 p.m. in Dover Auditorium

Social Inflation: Rising Tides In The Insurance Markets, Noah E. Heim

University Honors Program

Social inflation, despite its relative recency, has been a strong concern for some of the largest insurance carriers in the world. With claims costs increasing across broad markets, especially in casualty markets, insurers are racing to find the reason why. Increased claims costs can result in a number of negative effects on both insurance carriers as well as insurances buyers. Social inflation seems to be a key driver of these increased costs. Doing a deep dive into the validity of this claim and studying some potential causes as well as markets in which social inflation is occurring has led to …

Gender Analysis Of Publishing Among Medical Students In Dermatology, Michelle Militello, Mindy D. Szeto, Kayd J. Pulsipher, Abigail L. Meckley, Kristen H. Ward, Taylor Harp, Colby L. Presley, Cara Barber, Hope R. Rietcheck, Taylor M. Runion, Chandler W. Rundle, Robert P. Dellavalle

Research and Historical Works - 2021

No abstract provided.

Odei Pathways, Office Of Diversity, Equity, And Inclusion

Newsletters

GREETINGS 1-2

TOPIC OF THE MONTH

Diverse End of the Year Holidays 2-7

Supporting LGBTQIA+ People During the Holidays 7

PROGRAM UPDATES ODEI

Diversity, Equity and Inclusion Council 8-9

Burundi Presentation 9-10

Moving Beyond Bias 10

equity arcata 11

Network Updates Ongoing Learning Modules 11

PCSI381S Community Leadership in Action 12

WAYS TO ENGAGE

NCFDD-National Center for Faculty Development and Diversity 12-13

AUB 1.0 and 2.0 14

Equity Advocate 14

Training Calendar 15

Whiteness Accountability Space 15

Home Away from Home equity arcata distribution 12/11 16

ANNOUNCEMENTS

HSU Recognized as Equity Champions 17

MENSA Scholarship Opportunity BIPOC and LGBTQIA+ 18

Forum Selection Clauses, Non-Signatories, And Personal Jurisdiction, John F. Coyle, Robin J. Effron

Notre Dame Law Review

Who is bound by a forum selection clause? At first glance, the answer to this question may seem obvious. It is black letter law that a person cannot be bound to an agreement without her consent. In recent years, however, courts have not followed this rule with respect to forum selection clauses. Instead, they routinely enforce these clauses against individuals who never signed the contract containing the clause. Courts justify this practice on the grounds that it promotes litigation efficiency by bringing all of the litigants together in the chosen forum. There are, however, problems with enforcing forum selection clauses …

Black Leadership Zine, Aleem A., Hunter Richard, Gabriella C.

Student Zines

Leadership takes forms in different ways where the art o languages whispers subjectivity.

This zine project takes various definitions of leadership and presents it through a different lens of a political United States.

New York State Birth Through Five (Nysb5) Preschool Development Grant Needs Assessment Update Report (2021), Center For Human Services Research, University At Albany

Education & Early Childhood Development Reports and Research Briefs

In 2019, the New York State Council on Children and Families (CCF) in partnership with the Center for Human Services Research (CHSR) at the University at Albany, State University of New York conducted a comprehensive needs assessment of the state’s early childhood care and education system (ECCE). As noted in the 2019 New York State Birth Through Five (NYSB5) Preschool Development Grant Needs Assessment Report, the state’s expanded investment in ECCE infrastructure reflects a strong commitment to supporting young children and families. See https://www.ccf. ny.gov/files/4915/7773/1159/nysb5_na_report.pdf.

In March 2020, the lives of New Yorkers were upended by the COVID-19 pandemic in …

Automated Discovery And Interpretation Of Ada-Compliant Door Placards, John J. Feilmeier

Computer Science and Information Technology Faculty

A familiar difficulty to any new student on campus is making one’s way from classroom A to classroom B. Facilities with different wings, multiple floors, and irregular floorplans can magnify this challenge, while students with vision impairments are impacted even more by the challenge of identifying the destination. This thesis explored different methods of discovering Americans with Disabilities Act (ADA)- compliant room identifying placards (“plaques”) and identifying the text on the sign. The plaque detection was accomplished with both standard image manipulation techniques and a Histogram of Oriented Gradients (HOG) (Dalal & Triggs, 2005) object detector. The text reading utilized …

Quantum State Tomography Of Molecules By Ultrafast Diffraction, Ming Zhang, Shuqiao Zhang, Yanwei Xiong, Hankai Zhang, Anatoly A. Ischenko, Oriol Vendrell, Xiaolong Dong, Xiangxu Mu, Martin Centurion, Haitan Xu, R. J.Dwayne Miller, Zheng Li

Martin Centurion Publications

Ultrafast electron diffraction and time-resolved serial crystallography are the basis of the ongoing revolution in capturing at the atomic level of detail the structural dynamics of molecules. However, most experiments capture only the probability density of the nuclear wavepackets to determine the time-dependent molecular structures, while the full quantum state has not been accessed. Here, we introduce a framework for the preparation and ultrafast coherent diffraction from rotational wave packets of molecules, and we establish a new variant of quantum state tomography for ultrafast electron diffraction to characterize the molecular quantum states. The ability to reconstruct the density matrix, which …

Identifying Functional Profiles Of Challenging Behaviors In Autism Spectrum Disorder With Unsupervised Machine Learning, Emily Daskas

Computational and Data Sciences (MS) Theses

Machine learning and deep learning methods are becoming increasingly used in the understanding, identification, and improvement of the diagnosis and treatment of Autism Spectrum Disorder. People with ASD often exemplify challenging behaviors that can put their safety, education, and general quality of life at risk. Challenging behaviors are driven by one of four functions. The combination of common occurrences of challenging behaviors and their respective behavioral functions are unique to the individual and circumstance, and the most successful therapies account for both challenging behaviors and their respective functions. Therefore, it is important that research is done on these concepts to …

Rolling Submissions

The Prairie Light Review

No abstract provided.

Oranges, Maxwell Harris

The Prairie Light Review

No abstract provided.

Tongue Tied, Madelene Przybysz

The Prairie Light Review

No abstract provided.

Climate Change, Kendall Molina

The Prairie Light Review

No abstract provided.

Flowers, Linnea Sardina

The Prairie Light Review

No abstract provided.

Self Portrait, Raymond Loi

The Prairie Light Review

No abstract provided.

Rheological Properties Of Recyclable Polymer Matrices For Advanced Composite Applications, Rahul Shankar

Dissertations

This dissertation focuses on evaluating the rheological characteristics of a variety of recyclable polymer matrices, which can compete with thermosets in a wide range of specialized applications. Studying the fundamental solid and melt-state viscoelastic properties and establishing structure-property-processing relationships is critical for the widespread adoption of these novel recyclable polymers in commercial applications. The first chapter provides an introductory overview of the different recyclable polymer matrices and their applications including high performance thermoplastics as thermoset replacements in high energy composite manufacture, multifunctional specialty thermoplastics for additive manufacturing and next generation, reprocessable covalent adaptable networks for self-healing applications. Furthermore, the important …

Synthesis Of Molecular Probes For The Detection Of Toxic Analytes, Rashid Mia

Dissertations

Two different types of molecular probes have been synthesized. The first family of probes is the coumarin class of compounds. These chemodosimters are referred to as Low Molecular Weight Fluorescent probes (LMFP). The other type of molecular probe is a macrocycle known as a pillar[5]arene receptor.

The chemodosimters (2.12a-c and 3.12a) were synthesized in four to five steps. The photophysical properties were extensively studied in various solvent systems (DMSO, CH₃CN, DMF, MeOH, EtOH, Me₂CO, MeCO₂Et, CHCl₃, C₆H₅Me, and C₆H₆). Dimethyl sulfoxide (DMSO) …

The Relationship Between Principal Support And First-Year Teacher Job Satisfaction, Beau Hannah

Dissertations

The purpose of the study was to assess the relationship between the four dimensions of principal support and first-year teacher job satisfaction. First-year teachers responded to an online questionnaire that collected demographic data and information regarding principal support importance and overall job satisfaction, using a Likert scale. This questionnaire was developed to measure principal support and first-year teacher job satisfaction. The researcher used a combination of the Principal Support, Minnesota Satisfaction Questionnaire, and a collected of items addressing the importance of the principal supports, along with demographics of the respondents.

A multiple linear regression was used to predict to what …

Employee Engagement And The Role Of Time Perspective, Donna Valestro

Dissertations

Employee engagement is how employees think, feel, and form intentions to decide behavioral actions. A review of related literature indicated a central tension between employees and the work environment requires psychologically adapting and adjusting to cope with their perceptions of internal and external conditions. The employee’s goal is to stay as close to their authentic self as possible within the organizational environment to maintain their well-being. The psychological process comprises a temporal dimension represented as time perspective in this study. The purpose of this research is to determine if a relationship exists between employee engagement and time perspective.

This nonexperimental, …

Re-Framing Gender: An Analysis Of Journalism’S Social Media Characterization Of Female Presidential Candidates During The 2020 Presidential Election, Taylor Kiernan

Dissertations

The completion of this dissertation would not have been possible without those who supported me both academically and personally throughout this process.

I would like to thank my dissertation chair and mentor, Dr. Christopher Campbell whose expertise and guidance made this research possible. I would also like to thank my dissertation committee members Dr. David Davies, Dr. Cheryl Jenkins, Dr. Laura Stengrim, and Dr. Fei Xue, for their guidance and advice during the research process, as well as their expertise in the classroom which molded my abilities as a researcher during my time at The University of Southern Mississippi.

I …

Obstacles To The Implementation Of Criminal Justice Reform, Matt Allen

Dissertations

Mass incarceration or overincarceration has gained significant attention over the last two decades, and criminal justice reform seeks to address it. This study uses constructivist grounded theory to examine the implementation of criminal justice reform legislation in Mississippi. Mississippi was chosen as the study setting because the state has been recognized as a national leader in enacting reform legislation and it has one of the nation’s highest incarceration rates. It is well established that policy implementation affects outcomes. Therefore, if the policies Mississippi is implementing are effective and they are implemented correctly, it stands to reason the state could benefit …

Scholars' Mine Quick Facts November 2021, Nancy S. Krost

Scholars’ Mine Statistics

Scholars' Mine Quick Facts are monthly reports of downloads, page hits, and other information about works in the institutional repository of Missouri S&T. A map with downloads by region is also included.

Uranium Carbonate Complexes Demonstrate Drastic Decrease In Stability At Elevated Temperatures, Alexander Kalintsev, Artas Migdisov, Christopher Alcorn, Jason Baker, Joël Brugger, Robert A. Mayanovic, Nadib Akram, Xiaofeng Guo, Hongwu Xu, For Complete List Of Authors, See Publisher's Website.

College of Natural and Applied Sciences

Quantitative understanding of uranium transport by high temperature fluids is crucial for confident assessment of its migration in a number of natural and artificially induced contexts, such as hydrothermal uranium ore deposits and nuclear waste stored in geological repositories. An additional recent and atypical context would be the seawater inundated fuel of the Fukushima Daiichi Nuclear Power Plant. Given its wide applicability, understanding uranium transport will be useful regardless of whether nuclear power finds increased or decreased adoption in the future. The amount of uranium that can be carried by geofluids is enhanced by the formation of complexes with inorganic …

(R1463) On The Central Limit Theorem For Conditional Density Estimator In The Single Functional Index Model, Abbes Rabhi, Nadia Kadiri, Fatima Akkal

Applications and Applied Mathematics: An International Journal (AAM)

The main objective of this paper is to investigate the nonparametric estimation of the conditional density of a scalar response variable Y, given the explanatory variable X taking value in a Hilbert space when the sample of observations is considered as an independent random variables with identical distribution (i.i.d.) and are linked with a single functional index structure. First of all, a kernel type estimator for the conditional density function (cond-df) is introduced. Afterwards, the asymptotic properties are stated for a conditional density estimator when the observations are linked with a single-index structure from which we derive an central …

(R1508) Stability And Zero Velocity Curves In The Perturbed Restricted Problem Of 2 + 2 Bodies, Rajiv Aggarwal, Dinesh Kumar, Bhavneet Kaur

Applications and Applied Mathematics: An International Journal (AAM)

The present study investigates the existence and linear stability of the equilibrium points in the restricted problem of 2+2 bodies including the effect of small perturbations epsilon-1 and espilon-2 in the Coriolis and centrifugal forces respectively. The less massive primary is considered as a straight segment and the more massive primary a point mass. The equations of motion of the infinitesimal bodies are derived.We obtain fourteen equilibrium points of the model, out of which six are collinear and rest non-collinear with the centers of the primaries. The position of the equilibrium points are affected by the small perturbation in centrifugal …

Understory Vegetation Composition And Small Mammal Abundance In An Exotic Eucalyptus Forest Vs Adjacent Native Habitat, Kelly Mcfadden

Master of Science in Environmental Sciences and Management Projects

None provided

Measuring Hydraulic Conductivity Using Flexible Walled Permeameter And Astm Method D5084, Bradon Povah

Master of Science in Environmental Sciences and Management Projects

This project is a guide that details the protocol synthesized from the ASTM D5084-16a method, the Humboldt control panel manual, and the time spent learning the intricacies of the Permeability Cell instrument.