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Formation Of Pyrroloindolines And Alkylation Of N-Heterocycles With Trichloroacetimidates And Synthesis Of Quinoline Based Small Molecule Inhibitors Of Ghrelin O-Acyltransferase (Goat), Bhaskar Joshi

Dissertations - ALL

Pyrroloindolines and related systems are present in a large number of complex natural products. These core structures have generated considerable synthetic interest, as many of the compounds possess challenging, elaborate structures and interesting biological properties. Recently we have focused on using trichloroacetimidates for the synthesis of these fascinating molecules. Trichloroacetimidates can be used an electrophilic source of an alkyl group to form the pyrroloindoline directly from tryptamine derivatives. In this manner trichloroacetimidates provide a flexible solution to accessing highly functionalized pyrroloindoline core structures, needing only a catalytic amount of a Lewis acid to effect the requisite transformations.

Isatin (1H-indol-2,3-dione) based …

Rational Design Of Supported Metal Catalysts For Carbonyl Reduction During Biomass Upgrading, Xin Gao

Dissertations - ALL

Ketone hydrogenation:A model system of carbonyl (ketone) hydrogenation, acetone hydrogenation over supported Pt catalysts in the gas-phase fixed bed reactor was investigated to understand both the mechanism and rate controlling steps in a fundamental level. The experiments and outcomes include the detailed macro- and micro-kinetic analysis of hydrogenation of acetone. The apparent reaction orders of hydrogen and acetone, apparent activation energies, and observed kinetic isotope effects over a large range of temperatures and concentrations (compound partial pressures) are reported in this document. Generally speaking, the ketone hydrogenation over metal surfaces in vapor phase comply with the mechanism that hydrogen atoms …

Bactericidal Effects And Stability Of Ll-37 And Cama In The Presence Of Human Lung Epithelial Cells, Regina Geitani, Carole Ayoub Moubareck, Floriane Costes, Léa Marti, Gabrielle Dupuis, Dolla Karam Sarkis, Lhousseine Touqui

All Works

Cationic antimicrobial peptides (CAMPs) are important actors in host innate immunity and represent a promising alternative to combat antibiotic resistance. Here, the bactericidal activity of two CAMPs (LL-37, and CAMA) was evaluated against Pseudomonas aeruginosa (PA) in the presence of IB3-1 cells, a cell line derived from patients with cystic fibrosis. The two CAMPs exerted different effects on PA survival depending on the timing of their administration. We observed a greater bactericidal effect when IB3-1 cells were pretreated with sub-minimum bactericidal concentrations (Sub-MBCs) of the CAMPs prior to infection. These findings suggest that CAMPs induce the production of factors by …

Distribution And Characterization Of Rhyolites Of The Strawberry Volcanics -- Evolution Of A Major Rhyolite Field Associated With Columbia River Basalt Magmatism, Eastern Oregon, Usa, Chanel Leigh Dvorak

Dissertations and Theses

The Strawberry Rhyolites constitute a significant rhyolite field among the largest in Oregon. Aerial coverage of approximately 386 km² and an overall estimated volume of ~67 km³ using a median thickness for each unit. On the other hand, the total volume could be greater than 100 km³ if greater thicknesses apply. The Strawberry Rhyolites, a largely unknown mid-Miocene silicic volcanic rocks, crop out amongst voluminous flood basalt flows of the Columbia River Basalt Group (CRBG) in eastern Oregon. The eruptive activity of the Strawberry Rhyolites is currently constrained to span a period of about 2 million years, …

The Dark Realism Of Miyazawa Kenji: Social Activism In The Science-Fiction Children's Story, The Life Of Gusukō Budori, And Its Precursor Work, Elsiemae Ann Ito

Dissertations and Theses

Miyazawa Kenji (1896-1933) is widely known in Japan as a children's story writer and poet, but he was also grounded in real life as a teacher, soil scientist, and farmer. Recognizing the harsh realities for farmers in his native Iwate, he nonetheless dreamed of an ideal world, as seen in his stories. To better understand the dark realities of life in Iwate, Japan, Miyazawa changed his occupation from teacher to farmer, focusing more on social activism that would better the lives of the people in his community. His late children's story, The Life of Gusukō Budori (Gusukō Budori no …

Improved Bathymetry Leads To >4000 New Seamount Predictions In The Global Ocean – But Beware Of Phantom Seamounts!, C Yesson, Tb Letessier, A Nimmo-Smith, P Hosegood, As Brierley, M Hardouin, R Proud

School of Biological and Marine Sciences

Seamounts are important marine habitats that are hotspots of species diversity. Relatively shallow peaks, increased productivity and offshore locations make seamounts vulnerable to human impact and difficult to protect. Present estimates of seamount numbers vary from anywhere between 10,000 to more than 60,000. Seamount locations can be estimated by extracting large, cone-like features from bathymetry grids (based on criteria of size and shape). These predicted seamounts are a useful reference for marine researchers and can help direct exploratory surveys. However, these predictions are dependent on the quality of the surveys underpinning the bathymetry. Historically, quality has been patchy, but is …

The Impact Of Critical Incidents On Nurses And Midwives: A Systematic Review, Melanie Buhlmann, Beverley Ewens, Amineh Rashidi

Research outputs 2014 to 2021

Aims: To synthesise the existing literature, which focuses on the impact of critical incidents on nurses and midwives, and to explore their experiences related to the support they received in the current healthcare environment to move on from the event.

Design: Systematic review and qualitative synthesis.

Data sources: The electronic databases CINAHL, MEDLINE, PsycINFO, PubMed, Embase and Nursing and Allied Health (ProQuest) were systematically searched from 2013–2018, and core authors and journals identified in the literature were manually investigated.

Review methods: Qualitative studies of all research design types written in English were included according to the PRISMA reporting guidelines. The …

Effects Of Nitrogen Fertilization On The Production Of Panicum Maximum Cv. Ipr 86 Under Grazing, S. M. B. Lugão, L. R. De A. Rodrigues, E. B. Malheiros, J. J. Dos S. Abrahão, A. De Morais

IGC Proceedings (1977-2023)

The experiment was conducted at the Experimental Station of Paranavaí/IAPAR-PR-Brazil, from October 1998 to May 1999, to evaluate the effects of N fertilization on Panicum maximum cv. IPR 86 pastures. Four doses of N (0; 150; 300; and 450 kg.ha^-1.year^-1) were applied to pastures under rotational grazing with grazing cycles (GCs) of 40 days (5 days-grazing and 35 days-rest). It was used a randomized complete block design, with split-plots, and two replications per treatment, being the N-doses studied in the main plots and the GCs in the sub-plots. In all GCs the variables dry matter of …

Effects Of Management Strategies On Seed Production And Seedling Recruitment In Birdsfoot Trefoil-White Clover Mixtures, W. Ayalá, M. Carámbula, D. F. Risso, J. Hodgson, Peter D. Kemp

IGC Proceedings (1977-2023)

The effects of grazing management on seed production, seed bank size and seedling emergence patterns of Trifolium repens cv. Zapicán (WC) and Lotus corniculatus cv. San Gabriel (BFT) oversown swards were evaluated. A complete randomized block design with 4 replicate blocks was used, in which 4 grazing strategies (grazing all year (SI), summer spelling for seed production (S2), winter rest plus summer spelling (S3) and autumn rest plus summer spelling (S4)), were combined with two defoliation severalties (4 and 10 cm height post-grazing residuals). Plots of 110 m² were grazed monthly by sheep. Seed production, soil seed bank and …

Announcements For Japas 9(2), Japas Editors

Journal of Amish and Plain Anabaptist Studies

No abstract provided.

Positive Leadership Theory For Online Dissertation Mentoring, Lee Stadtlander

Journal of Educational Research and Practice

A number of theoretical models have been suggested for how to mentor doctoral students. However, they tend to rely on hierarchical and authoritarian relationships between the faculty and students. Such models tend to create dependency and fear of the faculty, resulting in a reluctance in coming to the mentor for guidance. Such models do not tend to work well with online adult doctoral students with jobs and families. This paper proposes a model of positive leadership for online doctoral mentors, where mentors are accessible and create an environment where success is assumed and social support is provided by both the …

Review Of: Handrick, Frances. 2019. Amish Women: Work And Change- An Investigation Into The Lives Of Amish Women In Pennsylvania And Ohio., Amy Schlabach

Journal of Amish and Plain Anabaptist Studies

I opened the dissertation with hopeful interest. Would “Amish Women: Work and Change” be the factual, realistic view I had hoped for so many times before? The British author, Frances M. Handrick, interviewed 30 Amish women in Pennsylvania and Ohio. She compares our lives with the lives of Amish women 30 to 50 years ago. She also gleans bits of information from other writers and researchers, and the end result is a mixture of fact and the usual stereotypes. I want to recognize that, from what I understand, Ms. Handrick researched and wrote the dissertation for her own use, not …

Review Of: Kleinsasser, Ian. 2019. Blessings And Burdens: 100 Years Of Hutterites In Manitoba., Martin Lutz

Journal of Amish and Plain Anabaptist Studies

Ian Kleinsasser’s short book on Hutterites in Manitoba deserves attention. It is based on three lectures given at the inaugural Jacob D. Maendel Lectures in 2019. This lecture series was established in honor of Jacob Maendel (1911-1972) in the context of the centennial preparation of permanent Hutterite settlement in Canada. The three lectures were held in Portage la Prairie, and as the book’s introduction points out, were attended by representatives of both Schmiedeleut I and II groups. Jacob D. Maendel was a prominent Schmiedeleut leader of his generation and a driving force in advancing Hutterite education. His initiative led to …

Agricultural Support For The Old Colony Mennonites Of Belize: A Collaborative Effort Between North American Old Order Mennonites And A Cornell Extension Educator, Judson Reid

Journal of Amish and Plain Anabaptist Studies

The Old Colony Mennonites of Belize practice a conservative form of Anabaptism where technology, dress and lifestyle choices are informed by church standards. Members live in a spatially contiguous Colony, which creates land pressure over time as population increases. The development of new Colonies is necessary for the Mennonites to participate in agricultural livelihoods. The Indian Creek Colony of Belize has experienced agricultural and economic hardships since its inception in the 1989 due to land costs, crop failures and debt structure. Old Order Mennonites of North America developed an outreach effort to assist with on-farm production of vegetable crops to …

Penn State Extension Services And Plain People: An Inside Perspective On A Trust-Based Relationship, Phillip Martin

Journal of Amish and Plain Anabaptist Studies

This perspective on Penn State Extension Services and plain people is based on my personal experiences as a plain person, in which I interacted with Extension Services first as a farmer, and then (while working on a doctorate) as a part of the Extension system. Penn State Extension started over a century ago and was deliberate in reaching out to plain (conservative Anabaptist) farmers since the beginning, which led to a history of trust-based cooperation. For all these successes there remain challenges to effective cooperation with certain plain individuals and subgroups. I suggest these challenges are broadly similar to those …

Hotline Number To Reach And Offer Agricultural Information To Plain Anabaptists During The Covid-19 Workplace Closures, Emily Shoop, Carly Becker, Nathan Glenn Briggs, Danielle Smarsh

Journal of Amish and Plain Anabaptist Studies

The Penn State Extension Animal Systems Team developed a toll-free hotline phone number to convey short educational messages to maintain contact and outreach to Pennsylvania’s animal producing Amish, Mennonite, and other plain Anabaptist populations. During the COVID-19 pandemic, Penn State Extension’s programming went largely online via webinars, online courses, and emails. This change in programming excluded a large sector of Pennsylvania farmers who do not use or have access to the internet and, as such, were liable to miss important best management practice reviews and timely updates in animal agriculture. The Animal Systems Hotline offered callers the choice to listen …

Providing Agricultural Information To Amish And Mennonite Farmers: Creative Adaptations To Wisconsin Extension Programs And Communications, Richard Halopka

Journal of Amish and Plain Anabaptist Studies

This service provider report taps into the experience of a longtime Extension Educator in Wisconsin. Pulling from his work in Clark County, WI, where Amish and Old Order Mennonites have been particularly important to the local agricultural economy, he provides examples of how Extension can modify programming to meet the needs of plain producers. Topics of interest to Amish and Mennonite farmers include nutrient management, forage quality, and farm safety. Areas of program modification include approaches to communication, training, and support in ways that are culturally sensitive to church restrictions. In-person training and informational voicemail recordings have been particularly useful …

Effective Communication And Programming When Working With Amish Farmers: Reflections From A Wisconsin Agriculture Educator, Vance Haugen

Journal of Amish and Plain Anabaptist Studies

The author, an agricultural educator who worked with the Amish in Wisconsin for over 30 years, discusses his outreach efforts, which have been focused on managed grazing, a method well suited to Amish producers. Managed grazing offers agronomic, economic, and ecological benefits. A key educational tool for communicating managed grazing practices is the pasture walk, and the author relates lessons learned from these events. The communal nature and focus on farmer-to-farmer information exchange is well received by Amish producers. It is helpful if pasture walk scheduling is done well in advance and is focused on farmer-based problems with farmer-based solutions …

Ohio’S Amish And Mennonite Produce Growers: Farm Trends, Information Needs, And Agricultural Communication Preferences, Brad Bergefurd

Journal of Amish and Plain Anabaptist Studies

This study (1) describes the characteristics of Ohio Amish and Mennonite produce farmers and their operations; (2) determines awareness of and participation in OSU Extension programs by Amish and Mennonite produce farmers; (3) determines the methods used by Amish and Mennonite produce farmers to acquire farming information; and (4) identifies subject matter needs of Amish and Mennonite produce farmers for future Extension programming. In order to provide effective future Extension programming efforts for this particular clientele, a mail survey was used to collect data from 345 Ohio Amish and Mennonite farmers who participate at Ohio produce auctions. They were asked …

The Success Of Plain People’S Produce Auctions And Partnership With Missouri Extension, James Quinn, John Kruse, Londa Nwadike, James C. Piñero, David Trinklein

Journal of Amish and Plain Anabaptist Studies

The number of produce auctions led by plain Anabaptist producers has surged since the mid-1990s. Typically grower-owned, these businesses are centralized facilities providing a wholesale market to area growers for a diverse group of buyers. For growers seeking an adequate living from growing produce, these facilities help reduce marketing time and product transportation, and provide frequent sales events that guarantee payment. As such, they have developed into a solid and long-standing market for local produce. However, plain growers have experienced challenges trying new crops or scaling up production. This article details how Missouri Extension assisted plain farmers with their challenges …

Methodological Considerations For Amish-Focused Opinion Research: Lessons From A Study Of Beliefs And Practices About Agriculture And The Environment, David Hockman-Wert

Journal of Amish and Plain Anabaptist Studies

Certain aspects of Amish agriculture have been studied extensively but much is still unknown about Amish environmental attitudes and beliefs. This is due, in part, to the difficulty of directly soliciting responses from adherents. This article—part of a larger study of the Kishacoquillas Valley Amish settlement in Mifflin County, Pennsylvania—reflects on methodological challenges that arose during a study on Amish environmental attitudes and behaviors. Farmers from two Amish groups, as well as two non-Amish groups used for comparison, were interviewed about their environmental attitudes. Recruiting Amish participants for interviews was difficult due to the limited use of modern telecommunications technology, …

Farm Food Safety Training For Amish Produce Growers Covered Under The Food Safety Modernization Act (Fsma), Luke Laborde, Jeffrey Stoltzfus, Kaila Thorn

Journal of Amish and Plain Anabaptist Studies

Commercial production of fruits and vegetables on Amish farms provides significant amounts of fresh produce that are regionally distributed through wholesale markets. In response to several multi-state foodborne disease outbreaks linked to contamination of fresh produce, the U.S. Food and Drug Administration (FDA) mandated farm food safety standards that most commercial produce growers must implement. Although there have been no foodborne disease outbreaks attributed to fresh produce grown on Amish farms, this regulation poses regulatory challenges for those who sell produce at wholesale produce auctions, cooperatives, and distribution warehouses. This article describes recent farm food safety standards issued by the …

Performing Amish Agrarianism: Negotiating Tradition In The Maintenance Of Pennsylvania Dairy Farms, Nicole Welk-Joerger

Journal of Amish and Plain Anabaptist Studies

Amish people have a reputation for being ecologically and environmentally conscientious. As numerous scholars in Amish and Plain Anabaptist studies have demonstrated, Amish views of the environment are diverse and ultimately anchored in the understanding that God made nature for human use. In these cases, Amish views of the environment could be described as much more anchored in traditional philosophical notions of “agrarianism” than “environmentalism.” In this article, I explore how some Amish approach agrarianism with a turn from more traditional farm life toward necessary economic engagement with multi-faceted operations and diversification. Based on intensive ethnographic research and participant observation, …

Caring For The Land And The Livestock: Anabaptist Agricultural Practices In Europe And Colonial Pennsylvania, Rebecca Shenton

Journal of Amish and Plain Anabaptist Studies

Anabaptists have a strong history of agricultural innovation and care for the land. Their innovative spirit was forged out of persecution, migration, and the need to survive in challenging circumstances. This article examines the agricultural practices of seventeenth- and eighteenth-century Swiss and South German Anabaptist farmers and those of eighteenth-century Anabaptist immigrants to Pennsylvania. European Anabaptist tenant farmers distinguished themselves by their family-centered mixed agriculture and their investment in both the land (using manure, lime, gypsum, and crop rotation to improve the soil) and livestock (improving natural meadows and planting pastures for fodder, maintaining clean barns, practicing confinement feeding, and …

Title Page And Table Of Contents 9(2), Japas Editors

Journal of Amish and Plain Anabaptist Studies

No abstract provided.

Guest Editor’S Introduction: Outreach And Applied Agriculture Research With Plain Anabaptists: Lessons Learned And Future Directions, Caroline Brock

Journal of Amish and Plain Anabaptist Studies

This issue of the Journal of Amish and Plain Anabaptist Studies (JAPAS) contributes to a dearth of literature on ways to understand how plain Anabaptist culture influences agri-environmental beliefs and practices and how it informs outreach and research. Only a few studies currently focus on outreach with plain Anabaptist growers (e.g., Brock, Ulrich-Schad, and Prokopy 2018; Bergefurd 2011; Jepsen and Mann 2015; Stoltzfus 2019; Hoorman and Spencer 2001/2002). This issue of JAPAS is the first comprehensive publication to include research articles and service provider reports focusing on plain people and agriculture. This issue addresses the history of Anabaptist …

Front Matter, Editors

Exile

No abstract provided.

Exile Talks To Poet Deborah Digges, Colin Bossen

Exile

No abstract provided.

Untitled (Artwork), Kate Graf

Exile

No abstract provided.

Body (Artwork), Todd Gys

Exile

No abstract provided.