Digital Commons Network^™

Human Monocyte-Derived Macrophage Responses To M. Tuberculosis Differ By The Host’S Tuberculosis, Diabetes Or Obesity Status, And Are Enhanced By Rapamycin, Blanca I. Restrepo, Arshad Khan, Vipul K. Singh, Erica De Leon, Genesis P. Aguillón-Durán, Eder Ledezma-Campos, David H. Canaday, Chinnaswamy Jagannath

School of Medicine Publications

Human macrophages play a major role in controlling tuberculosis (TB), but their anti-mycobacterial mechanisms remain unclear among individuals with metabolic alterations like obesity (TB protective) or diabetes (TB risk). To help discern this, we aimed to: i) Evaluate the impact of the host’s TB status or their comorbidities on the anti-mycobacterial responses of their monocyte-derived macrophages (MDMs), and ii) determine if the autophagy inducer rapamycin, can enhance these responses. We used MDMs from newly diagnosed TB patients, their close contacts and unexposed controls. The MDMs from TB patients had a reduced capacity to activate T cells (surrogate for antigen presentation) …

"A White-And-Negro Environment Which Is Seldom Spotlighted" The Twilight Of Jim Crow In The Postwar Urban Midwest, Brent M. S. Campney

History Faculty Publications

This article investigates white-black race relations in postwar urban Kansas. Focusing on seven small and mid-sized cities, it explores how white Kansans continued to maintain discrimination, segregation, and exclusion in these years, even as they yielded slowly to the demands of civil rights activists and their supporters. Specifically, it examines the means employed by whites to assert their dominance in social interactions; to discriminate in housing, employment, and commerce; and, in some cases, to defend their all-white (or nearly all-white) municipalities, the so-called sundown towns, from any black presence at all. In addition, it briefly discusses the white backlash which …

Flight Training For Commercial Remote Pilots, Michael Walach

Theses and Dissertations

A remote pilot training program, part of an sUAS course, were studied to determine the effectiveness and portability of the training curriculum. Students in a university unmanned aircraft systems course were the subjects, and multiple data points were collected over the 15 week program. No differences were found in student performance on the metrics used to assess the students regardless of who the students had as a flight instructor. Males scored higher than females on prior flight experience upon entering the course; however, neither gender nor prior aviation experience were significant contributing factors in student success either academically (written tests) …

Table Of Contents (Vol. 92, Issue 4)

University of Colorado Law Review

No abstract provided.

From The Crisis Of Critique To The Critique Of Crisis, Ben Golder

University of Colorado Law Review

No abstract provided.

Making The Critical Moves: A Top Ten In Progressive Legal Scholarship, Jorge L. Esquirol

University of Colorado Law Review

No abstract provided.

Past Prescient, Christopher Tomlins

University of Colorado Law Review

No abstract provided.

The Future Of Facts: The Politics Of Public Health And Medicine In Abortion Law, Aziza Ahmed

University of Colorado Law Review

While a great deal of public scrutiny has focused on how information circulates through online outlets including Twitter and Facebook, less attention has been devoted to how more traditional institutions traffic in factual assertions for the sake of setting a particular distributional agenda into motion.1 Of these more traditional institutions, courts play a central role in legitimating legal and factual claims in the process of applying and clarifying legal rules. In public health-related adjudication, courts play at least two important roles: first, judges and juries make decisions between competing sets of public health and medical claims and second, courts legitimate …

Racializing Environmental Justice, Eric K. Yamamoto, Jen-L W. Lyman, Susan K. Serrano

University of Colorado Law Review

No abstract provided.

Neutroalgebra For The Evaluation Of Barriers To Migrants’ Access In Primary Health Care In Chile Based On Prospector Function, Diego Silva Jiménez, Juan Alexis Valenzuela Mayorga, Mara Esther Roja Ubilla, Noel Batista Hernández

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Sets And Systems, Vol. 41, 2021, Florentin Smarandache, Mohamed Abdel-Basset, Said Broumi

Neutrosophic Sets and Systems

No abstract provided.

Inequalities In Girls’ Learning Opportunities Via Edtech: Addressing The Challenge Of Covid-19, Helen Crompton, Agnes Chigona, Katy Jordan, Christina Myers

Teaching & Learning Faculty Publications

The onset of the Covid-19 pandemic prompted school closures, which affected nearly 1.5 billion learners globally. Girls are likely to have experienced learning losses during the pandemic to a greater extent, as there are multiple barriers that influence gender disparities in accessing and benefiting from EdTech, including social inequalities or norms and technological constraints. Equity needs to be foregrounded when EdTech interventions are implemented, by considering disparities emerging from digital access, freedom, literacy, pedagogies, and design:

Digital access: Potential gender disparities in digital access, including at home, should be considered when EdTech interventions are designed.

Digital freedom: Social norms, as …

Edtech And Emergency Remote Learning: A Systematic Review, Helen Crompton, Diane Burke, Katy Jordan, Sam Wilson, Susan Nicolai, Christina Myers

Teaching & Learning Faculty Publications

An output of the EdTech Hub, https://edtechhub.org

Individualized Coaching To Improve Pre-School Quality: Perception Of Teachers And Administrators, Danielle Anna Picot

Honors Theses and Capstones

No abstract provided.

Impact Of An Educational Module On Female Collegiate Athlete Knowledge Regarding The Female Athlete Triad, Cayla Marie Barretto

Honors Theses and Capstones

The Female Athlete Triad was defined in women’s sport as early as 1992, by the American College of Sports Medicine (ACSM). The guidelines regarding the Triad emphasis the importance of education in the prevention of the disorder. However, there is little research supporting if this education is occurring and if it is effective. A quantitative, quasi-experimental study was conducted at the University of New Hampshire. Twenty-five female collegiate athletes participated in a pre-test, educational intervention, and post-test to determine baseline knowledge and if there was any improvement in knowledge after education. Percent changes in scores from pre-test and post-test were …

The Future Of Auditing: An Analysis Of Ai Implementation In The Big Four Accounting Firms, Alexander Michael Heye

Honors Theses and Capstones

The implementation of Artificial Intelligence (AI) technology has become somewhat of a hot topic within the modern business world. Many companies have chosen to embrace the potential that these systems have on the ways we can conduct business, while others are hesitant to “dip their toes” in the figurative waters of AI research and utilization. Auditing is no different from other industries in that firms are excited to see what potential these new innovations have in store for promoting a faster, more efficient, and more accurate audit. This review peers into how some Big 4 firms have made the first …

Does The Emigration Of Skilled Labor From Hungary Merit Being Called A Brain Drain?, Alexa Marie Mayo

Honors Theses and Capstones

No abstract provided.

A Critical Review Of Apraxia Of Speech And Childhood Apraxia Of Speech, Madison Joan Smith

Honors Theses and Capstones

The theories and neural bases of Apraxia of Speech (AOS) have long been debated. In 1861, Paul Broca identified two patients with speech/language impairments who became the basis for the theory on aphemia, now known as apraxia. Broca noted of patients with AOS that “there are cases in which the general faculty for language remains unaltered; where the auditory apparatus is intact; where all muscles—including those of speech and articulation—are under voluntary control; and where nevertheless, a cerebral lesion abolishes articulated language” (Broca, 1861/2000). The term “apraxia” was first introduced by Hugo Liepmann in 1908 and was described as “the …

Changing Representations Of The Second World War: Why We Fight, Victory At Sea, And The World At War, Maiah Vorce

Honors Theses and Capstones

No abstract provided.

Engineering Thermostable Regulators For Inducible Gene Expression In Thermophiles, Connor M. Joyce

Honors Theses and Capstones

Thermophilic bacteria have attracted research interest due to their ability to grow at high temperatures ranging from 45 °C to 75 °C with some extreme thermophiles able to survive nearly boiling temperatures. They are valuable sources of thermostable biocatalysts and many have great potential as industrial hosts for biofuel production because fermentation at high temperatures has advantages such as reduced processing costs and lower risk of contamination compared with mesophilic bacteria. For example, some Geobacillus species has been shown to have high solvent tolerance, making them good candidates as host for alcohol production. To develop them as industrial hosts, large …

Business Risk And Attest Service Fees: Understanding The Effect Of Low Fed Interest Rates On Bank Audit Fees, Lucas Erik Jones

Honors Theses and Capstones

No abstract provided.

Increment And Decrement Effects In Motion Induced Blindness, Sofia C. Lombardo

Honors Theses and Capstones

Motion induced blindness (MIB) refers to the perceptual disappearance of a stationary stimulus in the presence of a motion mask. The current study investigated the degree to which afterimages affect MIB inhibition when measured as a contrast detection threshold in a modified replication of White et al. (2020). Adult participants (N = 3) with normal or corrected-to-normal eyesight completed a series of target detection tasks while viewing a standard MIB stimulus with the motion mask removed that consisted of increment versus decrement inducer and target components. A univariate ANOVA data analysis procedure revealed a significant afterimage effect (Scheffé p < 0.0253) on contrast detection threshold was found for targets presented at an interstimulus interval of 500 ms. This effect was stronger for decrement targets compared to increment targets in the decrement inducer conditions. Based on a comparison with previous research in which the MIB effect was found to endure across interstimulus intervals up to 15500 ms, the current findings indicate that afterimages do not significantly influence contrast detection thresholds for MIB. Further research is necessary for determining the strength and duration of afterimage effects on contrast detection thresholds in MIB that may be caused by interaction with the motion mask.

Stressful Life Events And Postpartum Depression, Madison E. Laurent

Honors Theses and Capstones

No abstract provided.

Understanding The Factors That Influence Tweet Popularity, Kyle A. Jalbert

Honors Theses and Capstones

No abstract provided.

How Can An Economic Analysis Affect The Understanding Of A Court’S Decision?, Yanni N. Kakouris

Honors Theses and Capstones

No abstract provided.

Understanding Secret Consumer Purchases And Their Effects On Brands, Jenna M. Peterson

Honors Theses and Capstones

Relationships created between brands and consumers are very important to establish loyalty and ensure repeat purchases. Our research examines the different ways that brands can help consumers keep their purchases a secret and how these methods help to develop relationships with the consumers. We also examine how the different secrecy methods affect feelings linked to the brand, such as, guilt, satisfaction, and more. We hypothesize that the secrecy methods which lead a consumer to feelings of guilt will directly correlate with feelings of dissatisfaction with their purchase and a higher connection with the brand. We find that although consumers link …

Evaluating The Relationship Between Confidence And Anxiety During The Covid-19 Pandemic, Althea M. Devereux

Honors Theses and Capstones

No abstract provided.

Ethical Use Of Beauty In Advertising, Koca Chan

Honors Theses and Capstones

The use of beauty images in advertising has been generally deemed to be unethical in society, based on the general negative presupposition in modern western culture. The ethicalness of the display of high standards of beauty in advertisements is especially controversial and questionable in the advertising industry. Advertising watchdogs, social groups, and individuals have investigated the possibility of banning the display of high standards of beauty to be displayed in advertisings and publications. This paper argues that image advertising of high beauty standards may not be necessarily unethical in all situations. And under certain conditions, by considering and combining image(s) …

Uses Unaddressed: How Social Technologies Tacitly Allow Gender-Based Violence, Brooke J. Marston

Honors Theses and Capstones

Growing technological capabilities have enhanced and intensified the potential for surveillance in many areas of life. Particularly, the placement of advanced technology in the hands of everyday people has produced ample opportunities for interpersonal monitoring. This growing capacity to surveil others we know without sophisticated techniques has concerning implications for acts of gender-based violence and intimate partner violence, which often hinge on surveillance, isolation, and control. Often, technology is used to the advantage of abusers in achieving such ends, and the wealth of personal information that is often available online leaves users vulnerable to acts of gender-based violence such as …

The Effect Of The Covid-19 Pandemic On The Issuance Of Going Concern Opinions And Financial Restatements, Jessica Oswald

Honors Theses and Capstones

No abstract provided.