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2021

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Influencing Capitalist Attitudes To Drive More Capital Towards Social Good, Leah Michelle Burton Jan 2021

Influencing Capitalist Attitudes To Drive More Capital Towards Social Good, Leah Michelle Burton

Antioch University Dissertations & Theses

The purpose of this study is to better understand how to influence capitalist attitudes and drive more capital towards social good. This is why we must explore the prospect of emancipating the capitalists from capitalism. This study identifies capitalism as a form of oppression that is contributing to a newly developed ethics of capital, a term introduced in this study. Emancipatory action research and general systems theory were employed as the primary approaches to engaging a group of venture capitalists and finance professionals in activities and dialogues. Value2 is the theory of action I use to influence the attitudes of …


Self-Concept, Healthcare, And Leadership: Understanding The Lived Experiences Of Physician Leaders In Urban Community Healthcare Centers, Eric James Charlton Jan 2021

Self-Concept, Healthcare, And Leadership: Understanding The Lived Experiences Of Physician Leaders In Urban Community Healthcare Centers, Eric James Charlton

Antioch University Dissertations & Theses

Reducing disparities in health services delivery and outcomes is a continued challenge. The consistence of healthcare disparities, despite advances in medical technology and increased awareness of the problem, poses an ongoing test to the nation. There is a growing body of work that demonstrates providing access to good primary care may be the most effective intervention at hand. For over 40 years, community health centers have been providing quality, comprehensive primary care focusing on reducing health outcome disparities. Increased awareness is now emphasizing primary care elimination of health disparities within disadvantaged, underserved populations. A major failing of the system that …


Educating For Global Competence: Co-Constructing Outcomes In The Field: An Action Research Project, Kristina A. Van Winkle Jan 2021

Educating For Global Competence: Co-Constructing Outcomes In The Field: An Action Research Project, Kristina A. Van Winkle

Antioch University Dissertations & Theses

Capacity building for globally competent educators is a 21st Century imperative to address contemporary complex and constantly changing challenges. This action research project is grounded in positive psychology, positive organizational scholarship, relational cultural theory, and relational leadership practices. It sought to identify adaptive challenges educators face as they try to integrate globally competent teaching practices into their curricula, demonstrate learning and growth experienced by the educators in this project, and provide guidance and solutions to the challenges globally competent educators face. Six educators participated in this three-phase project, which included focus groups, reflective journal entries, and an exit interview. Data …


Teachers Of Color's Perception On Identity And Academic Success: A Reflective Narrative, Lynette Suliana Sikahema Finau Jan 2021

Teachers Of Color's Perception On Identity And Academic Success: A Reflective Narrative, Lynette Suliana Sikahema Finau

Antioch University Dissertations & Theses

Research and scholarship in multicultural education has consistently affirmed that as a result of the long standing racial academic achievement gap and the current teaching force not reflecting the changing demographics of students in the United States, students of color continue to be deprived from having teachers who look like them and who may bring similar life, social, and cultural experiences that can increase the value they place on academics. The purpose of this study was to explore the lived experiences of teachers of color and how they perceive their identity as significant and meaningful to their profession and its …


Strengthening Organizational Performance Through Integration Of Systems Leadership, Participatory Communication, And Dynamic Capabilities, Esther Ewurafuah Sackey Jan 2021

Strengthening Organizational Performance Through Integration Of Systems Leadership, Participatory Communication, And Dynamic Capabilities, Esther Ewurafuah Sackey

Antioch University Dissertations & Theses

This dissertation seeks to include systems leadership and participatory communication as facilitators of the elements that enhance dynamic organizational capabilities to improve performance. The study employs the normative theory-building process to show how systems leadership and participatory communication can facilitate and enhance dynamic capabilities. Specifically, this dissertation offers an integrative model that combines systems leadership, participatory communication, and dynamic capabilities. The proposed integrative model is accompanied by a series of propositions that extend the dynamic capabilities theory through the integration of systems leadership and participatory communication. The potential relevance and application of the proposed model are demonstrated through multiple case …


Effects Of Sacubitril/Valsartan On Cardiac Function, Mitochondrial Quality And Autophagy In A Rat Model With Chronic Mitral Regurgitation, Lalida Tantisuwat Jan 2021

Effects Of Sacubitril/Valsartan On Cardiac Function, Mitochondrial Quality And Autophagy In A Rat Model With Chronic Mitral Regurgitation, Lalida Tantisuwat

Chulalongkorn University Theses and Dissertations (Chula ETD)

Sacubitril/Valsartan (S/V), an angiotensin receptor blocker-neprilysin inhibitor (ARNi), has demonstrated beneficial outcomes in heart failure (HF) patients. However, the effects of the drug in mitral regurgitation (MR) condition are not thoroughly elucidated. The objective of this study was to investigate the effects of S/V compared with valsartan (Val) on cardiac function, mitochondrial quality and autophagy in a rat model with chronic MR. MR was induced in male, Sprague-Dawley, rats (n=24), while the other 6 rats underwent sham surgery. Four weeks post-surgery, the MR rats were randomly divided into 3 groups: MR (n=8), Val (n=7), and S/V (n=8); one rat was …


The Acute And Chronic Effects Of Electromagnetic Radiation Of Mobile Phone On Cardiac Function And Heart Rate Variability In Healthy Dogs, Dong Nhut Khanh Van Jan 2021

The Acute And Chronic Effects Of Electromagnetic Radiation Of Mobile Phone On Cardiac Function And Heart Rate Variability In Healthy Dogs, Dong Nhut Khanh Van

Chulalongkorn University Theses and Dissertations (Chula ETD)

The study aimed to determine the effects of acute and chronic exposures of electromagnetic radiation (EMR) emitted from mobile phone (MP) on cardiac structure and function, as well as autonomic control to the heart in healthy dogs. Seven male beagles were enrolled in this study. The study consisted of two parts: (1) the acute effects of EMR from MP on electrocardiography (ECG), blood pressure (BP), heart rate variability (HRV), and body’s surface temperature; and (2) the chronic effects of EMR from MP on ECG, echocardiography, BP, cardiac biomarkers (i.e., cardiac troponin I–cTnI), HRV, and body’s surface temperature in healthy conscious …


Examining University Stakeholders' Perception Of The Implementation Of Internationalization In Higher Education Institutions In The Uae, Mohammed Madi Yousif Jan 2021

Examining University Stakeholders' Perception Of The Implementation Of Internationalization In Higher Education Institutions In The Uae, Mohammed Madi Yousif

Dissertations

The globalization of economies and societies worldwide, has brought massive transformations in the field of higher education, creating a context to include an ‘international’ dimension in higher education institutions (HEIs). Global learning is essential in the development of cognitive skills, as well as for increased success among academics, hence institutional stakeholders such as administrators, faculty, and students are key participants in initiatives to internationalize academia. The current study examines the perspectives of institutional stakeholders (top administrators, faculty, and students) concerning the process and implementation of internationalization of higher education in the UAE, revealing its potential benefits and challenges. In a …


Process Mining Analytics For Industry 4.0 With Graph Signal Processing, Georgios Drakopoulos, Eleanna Kafeza, Phivos Mylonas, Spyros Sioutas Jan 2021

Process Mining Analytics For Industry 4.0 With Graph Signal Processing, Georgios Drakopoulos, Eleanna Kafeza, Phivos Mylonas, Spyros Sioutas

All Works

Process mining is the art and science of (semi)automatically generating business processes from a large number of logs coming from potentially heterogeneous systems. With the recent advent of Industry 4.0 analog enterprise environments such as floor shops and long supply chains are bound to full digitization. In this context interest in process mining has been invigorated. Multilayer graphs constitute a broad class of combinatorial objects for representing, among others, business processes in a natural and intuitive way. Specifically the concepts of state and transition, central to the majority of existing approaches, are inherent in these graphs and coupled with both …


Translanguaging And Reading Comprehension In A Second Language, Muhammad Asif Qureshi, Ahmad Aljanadbah Jan 2021

Translanguaging And Reading Comprehension In A Second Language, Muhammad Asif Qureshi, Ahmad Aljanadbah

All Works

The current study examined the impact of translanguaging on second language reading comprehension. The study involved an experimental and a control group. The participants in the experimental group (n = 38) were offered four opportunities to engage Arabic–their first language–in comprehending a text in English. These occasions for translanguaging included: (a) receiving Arabic glosses (i.e., only meaning) for key terms in the text, (b) employing their first language for summarizing four paragraphs from the passage, (c) using their first language in discussion for comparing summaries with peers, and (d) consulting the Arabic meanings (provided) while attempting the vocabulary items. After …


A Data-Based Guiding Framework For Digital Transformation, Zakaria Maamar, Saoussen Cheikhrouhou, Said Elnaffar Jan 2021

A Data-Based Guiding Framework For Digital Transformation, Zakaria Maamar, Saoussen Cheikhrouhou, Said Elnaffar

All Works

This paper presents a framework for guiding organizations initiate and sustain digital transformation initiatives. Digital transformation is a long-term journey that an organization embarks on when it decides to question its practices in light of management, operation, and technology challenges. The guiding framework stresses out the importance of data in any digital transformation initiative by suggesting 4 stages referred to as collection, processing, storage, and dissemination. Because digital transformation could impact different areas of an organization for instance, business processes and business models, each stage suggests techniques to expose data. 2 case studies are adopted in the paper to illustrate …


A Study Of The Effects Of The Covid-19 Pandemic On College Student Academic Dishonesty, Drake Fromenthal Jan 2021

A Study Of The Effects Of The Covid-19 Pandemic On College Student Academic Dishonesty, Drake Fromenthal

Honors Capstones

No abstract provided.


Disability As Metaphor And Lived Experience In Samuel Richardson's Pamela And Sarah Scott's Millenium Hall, Jason S. Farr Jan 2021

Disability As Metaphor And Lived Experience In Samuel Richardson's Pamela And Sarah Scott's Millenium Hall, Jason S. Farr

English Faculty Research and Publications

No abstract provided.


Review Of Contest, Translation, And The Chaucerian Text, Elizaveta Strakhov Jan 2021

Review Of Contest, Translation, And The Chaucerian Text, Elizaveta Strakhov

English Faculty Research and Publications

No abstract provided.


A Primer On Opposing Construction Of Wind Farms Near Public-Use Airports, Alan Armstrong Jan 2021

A Primer On Opposing Construction Of Wind Farms Near Public-Use Airports, Alan Armstrong

Journal of Air Law and Commerce

We are witnessing an explosion in the construction of wind turbine generators, cell phone towers, and television/radio broadcast towers around the United States. The statutes, rules, regulations, and police guidance addressing when and where such structures can be erected near public-use airports are complex and intricate. The Federal Aviation Administration (FAA) focuses more on subjective than objective criteria in assessing whether an obstruction to air navigation is a hazard to air navigation.

To the extent the FAA conducts studies to determine whether an obstruction is a hazard, the courts are not uniform in assessing the effects of FAA studies. In …


Mahanoy Area School District V. B.L.: The Court Protects Student Social Media But Leaves Unanswered Questions, David L. Hudson Jr. Jan 2021

Mahanoy Area School District V. B.L.: The Court Protects Student Social Media But Leaves Unanswered Questions, David L. Hudson Jr.

Law Faculty Scholarship

In Mahanoy Area School District v. B.L.: The Court Protects Student Social Media but Leaves Unanswered Questions, published in the Cato Supreme Court Review, David L. Hudson Jr. analyzes the U.S. Supreme Court’s landmark decision addressing the scope of public schools’ authority over off-campus student speech on social media. Situating Mahanoy within the Court’s broader K–12 student speech jurisprudence—from Barnette and Tinker to Fraser, Hazelwood, and Morse—the Article explains how the Court declined to adopt a categorical rule excluding off-campus speech from regulation while nevertheless ruling in favor of the student. The majority recognized diminished school …


Coming To Terms: Using Contract Theory To Understand The Detroit Water Shutoffs, Marissa Jackson Sow Jan 2021

Coming To Terms: Using Contract Theory To Understand The Detroit Water Shutoffs, Marissa Jackson Sow

Law Faculty Publications

After the City of Detroit underwent financial takeover and filed the largest municipal bankruptcy in American history in 2013, the city’s emergency manager encouraged mass water shutoffs as a way of making the city’s water utility a more attractive asset for sale—and for privatization—by ridding the water department of its association with bad debt. The sale never took place, but the water shutoff, too, became the largest ever in American history, with over 141,000 homes subjected to water disconnections over a period of over six years. The governor of the State of Michigan ordered that the shutoffs be temporarily suspended …


Catalog 2021-2022, University Of North Florida Jan 2021

Catalog 2021-2022, University Of North Florida

UNF Course Catalogs

No abstract provided.


Flight And Dietary Antioxidants Influence Antioxidant Expression And Activity In A Migratory Bird, Kristen J. Demoranville, Wales A. Carter, Barbara J. Pierce, Scott R. Mcwilliams Jan 2021

Flight And Dietary Antioxidants Influence Antioxidant Expression And Activity In A Migratory Bird, Kristen J. Demoranville, Wales A. Carter, Barbara J. Pierce, Scott R. Mcwilliams

Biology Faculty Publications

Ecologically-relevant factors such as exercise and diet quality can directly influence how physiological systems work including those involved in maintaining oxidative balance; however, to our knowledge, no studies to date have focused on how such factors directly affect expression of key components of the endogenous antioxidant system (i.e., transcription factors, select antioxidant genes, and corresponding antioxidant enzymes) in several metabolically active tissues of a migratory songbird. We conducted a 3-factor experiment that tested the following hypotheses: (H1) Daily flying over several weeks increases the expression of transcription factors NRF2 and PPARs as well as endogenous antioxidant genes (i.e., CAT, SOD1, …


A Complex Interplay Between Balancing Selection And Introgression Maintains A Genus-Wide Alternative Life History Strategy, Kalle Tunstrom, Alyssa Woronik, Joseph J. Hanly, Pasi Rastas, Anton Chichvarkhin, Andrew D. Warren, Akito Kawahara, Sean D. Schoville, Vincent Ficarrotta, Adam H. Porter, Ward B. Watt, Arnaud Martin, Christopher W. Wheat Jan 2021

A Complex Interplay Between Balancing Selection And Introgression Maintains A Genus-Wide Alternative Life History Strategy, Kalle Tunstrom, Alyssa Woronik, Joseph J. Hanly, Pasi Rastas, Anton Chichvarkhin, Andrew D. Warren, Akito Kawahara, Sean D. Schoville, Vincent Ficarrotta, Adam H. Porter, Ward B. Watt, Arnaud Martin, Christopher W. Wheat

Biology Faculty Publications

Alternative life-history strategies (ALHS) are genetic polymorphisms generating phenotypes differing in life histories that generally arise due to metabolic resource allocation tradeoffs. Although ALHS are often be limited to a single sex or populations of a species, they can, in rare cases, be found among several species across a genus. In the butterfly genus Colias, at least a third of the species have a female limited ALHS called Alba. While many females develop brightly pigmented wings, Alba females reallocate nitrogen resources used in pigment synthesis to reproductive development, producing white-winged, more fecund females. Whether this ALHS evolved once or …


Law's Ability To Further The "Menstrual Movement", Christopher A. Cotropia Jan 2021

Law's Ability To Further The "Menstrual Movement", Christopher A. Cotropia

Law Faculty Publications

"The current menstrual movement calls for overcoming the cultural stigma associated with menstruation, achieving “menstrual equity,” and ending “period poverty.” The stigma the movement seeks to address is that menstruation is seen as taboo, unclean, and impure. The movement’s aims are twofold: First, it wants to increase awareness of menstruation and remove discrimination against those who menstruate, thus achieving menstrual equity. Second, it intends to provide greater access to menstrual hygiene products (“MHPs”), particularly for homeless and lower income people, thus eliminating period poverty. To achieve these goals, the movement is advocating to legislatively eliminate the “tampon tax” and increase …


Association Between Working Condition And Musculoskeletal Disorders (Msds) Among Female Garmentworkers In Khan Mean Chey, Phnom Penh City, Cambodia, Try Phally Jan 2021

Association Between Working Condition And Musculoskeletal Disorders (Msds) Among Female Garmentworkers In Khan Mean Chey, Phnom Penh City, Cambodia, Try Phally

Chulalongkorn University Theses and Dissertations (Chula ETD)

Musculoskeletal disorders (MSDs) are a serious public health issue in both industrialized and developing countries. This study aims to investigate the prevalence of musculoskeletal symptoms and the association between working conditions and MSDs among female garment workers in Khan Mean Chey, Phnom Penh city, Cambodia. A cross-sectional research design was conducted among 423 female garment workers. Data collection was convenient sampling through face-to-face interview using a structured questionnaire consisted of socio demographics, working conditions, and the Standardized Nordic Questionnaire for musculoskeletal symptoms assessment during the period between April and May 2022. Descriptive statistics was used to present the prevalence of …


การปรับปรุงประสิทธิภาพพลังงานโดยการจัดตารางในการจ่ายน้ำมันของคลังน้ำมันแห่งหนึ่ง, ศุภณัฐ สีทา Jan 2021

การปรับปรุงประสิทธิภาพพลังงานโดยการจัดตารางในการจ่ายน้ำมันของคลังน้ำมันแห่งหนึ่ง, ศุภณัฐ สีทา

Chulalongkorn University Theses and Dissertations (Chula ETD)

งานวิจัยนี้นำเสนอการปรับปรุงประสิทธิภาพพลังงานโดยการจัดตารางการเติมน้ำมันให้กับรถบรรทุกน้ำมันที่เข้ามารับน้ำมันในคลังน้ำมันกรณีศึกษา โดยการจัดตารางการรับน้ำมันจะคำนึงถึงความสำคัญของปั๊มมากกว่าคำสั่งซื้อน้ำมัน และคำสั่งซื้อที่ถูกจัดตารางเป็นคำสั่งซื้อที่สามารถรับน้ำมันได้หลายชนิดในเวลาเดียวกัน ประกอบกับการใช้งานปั๊มที่ปั๊มแต่ละตัวสามารถจ่ายน้ำมันให้กับรถบรรทุกน้ำมัน 2-5 คันพร้อม ๆ กัน ซึ่งกระบวนการจัดตารางจะเป็นแบบฮิวริสติกพลวัต (Dynamic Heuristic) โดยอาศัยกฎ Least Operation Remaining และ Largest Total Processing Time ในการจัดลำดับความสำคัญของใบคำสั่งซื้อ และการจัดตารางเวลาที่คำนึงถึงจำนวนหัวจ่ายที่ถูกใช้งาน งานที่เหลืออยู่ในระบบ และการใช้พลังงานของปั๊มที่เปลี่ยนแปลงตามเวลา จากการจัดตารางด้วยฮิวริสติกพลวัตทั้งหมด 6 วิธี พบว่าค่าพลังงานที่ใช้ต่อปริมาณน้ำมัน 1 ลิตรลดลงร้อยละ 42 จากการใช้พลังงานเฉลี่ยเดิม 0.42 วัตต์ชั่วโมงต่อลิตร เหลือเพียง 0.24 วัตต์ชั่วโมงต่อลิตร มีผลให้ประหยัดค่าใช้จ่ายด้านพลังงานเฉลี่ยของปั๊มเป็นจำนวนเงิน 199,006.25 บาทต่อเดือน ทั้งนี้การจัดตารางดังกล่าวดำเนินการภายใต้กระบวนการจัดตารางที่รู้จำนวนงานล่วงหน้า ไม่มีการเปลี่ยนแปลงจำนวนงานระหว่างการจัดตาราง ที่ถูกออกแบบโดยการคำนึงถึงลักษณะทางกายภาพของคลังน้ำมันเป็นหลัก


A Causal Model For The Quality Of Nursing Work Life Among Professional Nurses In Public Hospitals, Thailand, Pattaramon Tubsoongnoen Jan 2021

A Causal Model For The Quality Of Nursing Work Life Among Professional Nurses In Public Hospitals, Thailand, Pattaramon Tubsoongnoen

Chulalongkorn University Theses and Dissertations (Chula ETD)

This cross-sectional study aimed to develop and test causal relationships between transformational leadership, job characteristics, organizational climate, job satisfaction, and quality of nursing work life among professional nurses in Thailand. The hypothesized model was conducted based on Kanter’s theory of structural empowerment. A multi-stage sampling technique was utilized to recruit 392 Thai professional nurses from 22 hospitals who met the inclusion criteria. Research instruments consisted of demographic data form, Multifactor Leadership Questionnaire, Job Content Questionnaire, Organizational Climate Questionnaire, Nurses’ Job Satisfaction Scale, and the Thai version of Brooks’ Quality of Nursing Work Life survey. The validity of all instruments was …


Venom Characterization And Toxicology Of Box Jellyfish Chironex Indrasaksajiae, Chanikarn Yongstar Jan 2021

Venom Characterization And Toxicology Of Box Jellyfish Chironex Indrasaksajiae, Chanikarn Yongstar

Chulalongkorn University Theses and Dissertations (Chula ETD)

Box jellyfish is considered one of the most venomous animals. The genus Chironex (C. indrasaksajiae) is a multi-tentacle box jellyfish found in Thai waters that are dangerous to humans, particularly the venom that could cause death within minutes. This study aimed to perform a proteomic approach to characterize the protein components of C. indrasaksajiae venom. A total of 532 unique protein groups were identified, including toxins and proteins essential for nematocyte development and nematocyst formation (nematogenesis). Toxins CfTX-1 and CfTX-2, with sequence coverage of 39.3 percent and 34.8 percent, respectively, are the most abundant in the venom of C. indrasaksajiae. …


Substrate Binding Mechanism Of Glycerophosphodiesterase Towards Pesticides And Improvement Of Stability By Mutational Analysis, Nayana Bhat Jan 2021

Substrate Binding Mechanism Of Glycerophosphodiesterase Towards Pesticides And Improvement Of Stability By Mutational Analysis, Nayana Bhat

Chulalongkorn University Theses and Dissertations (Chula ETD)

Molecular dynamics studies have been providing a great number of atomistic details of biological systems to understand enzymatic activity and underlying reaction mechanisms. Herein, molecular dynamic (MD) simulations were employed to study the binding mechanisms of organophosphate pesticides towards two metallohydrolases, i.e., glycerophosphodiesterase (GpdQ) and methyl parathion hydrolase (MPH). OPH are the class of enzymes which breaks down harmful organophosphates, including the pesticides and warfare agents into less harmful byproducts. Hence, these enzymes are excellent candidates for bioremediation. In the present study, various nonspecific organophosphate pesticides were docked into GpdQ and MPH enzymes to construct the pesticide/protein complex for performing …


Analysis Of Protein-Protein Interaction Network From Leukocyte Transcriptomic Profiles In Severe Covid -19 Patients, Pakorn Sagulkoo Jan 2021

Analysis Of Protein-Protein Interaction Network From Leukocyte Transcriptomic Profiles In Severe Covid -19 Patients, Pakorn Sagulkoo

Chulalongkorn University Theses and Dissertations (Chula ETD)

Coronavirus disease 2019 (COVID-19) still provides global public health issues although several vaccines and antiviral agents have been developed. Some patients experience severe conditions needed medical intensive care, and some are dead due to the failure of treatments. Therefore, identifying the key genes and underlying molecular mechanisms is necessary to discover precisely targeted drugs. Analysis of protein-protein interaction (PPI) networks provides invaluable information to find disease mechanisms and effective alternative drugs. Hence, PPI network analysis based on leukocyte transcriptomic profiles of severe COVID-19 collected from Gene Expression Omnibus (GEO) DataSets was proposed for this study. A network diffusion method called …


Characterization Of Aberrant Mtor Signaling Pathway In U87mg Glioblastoma Cell Line By Quantitative Phosphoproteomics, Nuttiya Kalpongnukul Jan 2021

Characterization Of Aberrant Mtor Signaling Pathway In U87mg Glioblastoma Cell Line By Quantitative Phosphoproteomics, Nuttiya Kalpongnukul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Glioblastoma (GBM) is one of the most damaging primary brain tumors with a poor prognosis. GBM is associated with an abnormality of the mTOR signaling pathway, consisting of two distinct kinase complexes: mTORC1 and mTORC2. The protein complexes play critical roles in cellular metabolism, proliferation, cell survival, cell migration through the cytoskeletal organization, and DNA damage response in cancers. Nevertheless, the functions of mTORC2 are less unraveled. This study investigated the aberrant mTORC2 signaling pathway in glioblastoma cells using stable isotope labeling, phosphopeptide enrichment, and LC-MS/MS. We performed the quantitative phosphoproteomic analysis of U87MG grade IV glioma cells treated with …


Epidemiology, Molecular Genetic, And Evolutionary Analysis Of Humanrotavirus A Infection In Thailand, Fajar Budi Lestari Jan 2021

Epidemiology, Molecular Genetic, And Evolutionary Analysis Of Humanrotavirus A Infection In Thailand, Fajar Budi Lestari

Chulalongkorn University Theses and Dissertations (Chula ETD)

Rotavirus A (RVA) infection remains one of the major causes of viral diarrhea in young children worldwide. Despite the success of RVA vaccines including RotaTeq in significantly reducing morbidity and disease severity associated with hospitalization, national immunization against RVA have only just begun in Thailand in 2020. Consequently, possible RV vaccine shedding among pediatric vaccine recipients has not been rigorously documented here.The first part of my study was summarize the virology, disease burden, prevalence, distribution of genotypes and seasonality of RVs, and the current status of RV vaccination in Southeast Asia (Cambodia, Indonesia, Lao People’s Democratic Republic, Malaysia, Myanmar, Philippines, …


Production And Characterization Of Mannanase From Aureobasidium Sp. For Mannooligosaccharide Preparation From Spent Coffee Ground, Syahriar Nur Maulana Malik Ibrahim Jan 2021

Production And Characterization Of Mannanase From Aureobasidium Sp. For Mannooligosaccharide Preparation From Spent Coffee Ground, Syahriar Nur Maulana Malik Ibrahim

Chulalongkorn University Theses and Dissertations (Chula ETD)

The aims of this study are to produce and characterize mannanase from the selected Thai Aureobasidium strain and use the enzyme for hydrolysis of spent coffee ground extract (SCGE) to prepare mannooligosaccharide (MOs). The optimum condition for SCGE extraction by hot water was 1:30 solid to liquid ratio with 60 min incubation time at 121°C 15 lbs per in2. The maximum yield was 9.5 g/100 g substrate. The second dominant composition of SCGE was hemicellulose at 28 %. Aureobasidium pullulans NRRL 58524 was selected as the best mannanase producer with 8.07 U/mL. The mannanase production medium was optimized by using …