Digital Commons Network^™

Quantifying Phosphatidylethanol From Blood Samples, James V. Defrancesco, Majid Afshar

Chemistry: Faculty Publications and Other Works

Disclosed herein is a method for quantifying phosphatidylethanol (“ PEth ”), direct ethanol biomarker, from a blood sample using gas chromatography mass spectrometry. The method disclosed herein is useful for diagnosing acute and chronic alcohol abuse.

A Dosimetric Study On Photon Beam Energies With And Without A Flattening Filter In Sbrt Treatments For Prostate Cancer, Alexis F. Puruleski

Masters Projects

Purpose: The role of radiation therapy in managing prostate cancer has developed and improved greatly throughout the years. The purpose of this study was to analyze a newly developing method of treatment practices with two different therapy energies.

Methods: This retrospective study pulled patient data from the facility’s treatment planning system database who had primary prostate cancer treated to the prostate bed. Each patient was planned for the same treatment technique with two different beam energies, 6X and 6FFF (flattening filter free).

Results: A two-sample t-test was done to compare means of the max doses to the bladder, rectum, and …

A Single Cell Pair Mechanical Interrogation Platform To Study Cell–Cell Adhesion Mechanics, Amir Monemianesfahani

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Cell-cell adhesion complexes are macromolecular adhesive organelles that integrate cells into tissues. Perturbations of the cell-cell adhesion structure or relatedmechanotransduction pathways lead to pathological conditions such as skin and heart diseases, arthritis, and cancer. Mechanical stretching has been used to stimulate the mechanotransduction process originating from the cell-cell adhesion and cell-extracellular matrix (ECM) complexes. The current techniques, however, have limitations on their ability to measure the cell-cell adhesion force directly and quantitatively. These methods use a monolayer of cells, which makes it impossible to quantify the forces within a single cell-cell adhesion complex. Other methods using single cells or cell …

Characterization Of Response To Atezolizumab + Bevacizumab Versus Sorafenib For Hepatocellular Carcinoma: Results From The Imbrave150 Trial, Riccardo Lencioni

All Publications

Background: IMbrave150 is a phase III trial that assessed atezolizumab + bevacizumab (ATEZO/BEV) versus sorafenib (SOR) in patients with unresectable hepatocellular carcinoma (HCC) and demonstrated a significant improvement in clinical outcomes. Exploratory analyses characterized objective response rate (ORR), depth (DpR), and duration of response (DoR), and patients with a complete response (CR).

Methods: Patients were randomized 2:1 to intravenous ATEZO (1200 mg) + BEV (15 mg/kg) every 3 weeks or oral SOR (400 mg) twice daily. Tumors were evaluated using Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1) and HCC-modified RECIST (mRECIST). ORR by prior treatment and largest …

Gaiety, October 1975

Gaiety, 1975-1977

Co-Editors: Gary Poe, Lila Baker. News Editor: Fred Harris. Graphics: Jim Alley

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

The Variability Of Seawater Carbonate Chemistry In Two Florida Urban Mangrove Ecosystems, Alexandrina R. Rangel

All HCAS Student Capstones, Theses, and Dissertations

Anthropogenic carbon dioxide (CO₂) emissions into the atmosphere are yielding serious impacts across the world’s ocean, including ocean acidification, sea level rise, and increasing seawater temperature. However, these changes are not occurring uniformly across all marine ecosystems. Coastal ecosystems, such as mangroves, already experience extreme and variable environmental conditions due to natural biogeochemical and physical processes. The goal of this study was to document small-scale variability in two urban mangrove ecosystems to gain insight into how ocean acidification will manifest within these systems. Using a stand-up paddleboard, a suite of sensors, and traditional bottle sampling techniques, we measured …

Physical Activity As A Mediator Between Race/Ethnicity And Changes In Multimorbidity., Jason T. Newsom, Emily C. Denning, Miriam R. Elman, Anda Botoseneanu, Heather G. Allore, Corey L. Nagel, David A. Dorr, Ana R. Quiñones

Psychology Faculty Publications and Presentations

Studies report racial/ethnic disparities in multimorbidity (≥2 chronic conditions) and their rate of accumulation over time as well as differences in physical activity. Our study aimed to investigate whether racial/ethnic differences in the accumulation of multimorbidity were mediated by physical activity among middle-aged and older adults.

Pgc1Α Is Required For The Renoprotective Effect Of Lncrna Tug1 In Vivo And Links Tug1 With Urea Cycle Metabolites, Li Li, Jianyin Long, Koki Mise, Daniel L Galvan, Paul A Overbeek, Lin Tan, Shwetha V Kumar, Wai Kin Chan, Phillip L Lorenzi, Benny H Chang, Farhad R Danesh

Faculty, Staff and Students Publications

lncRNA taurine-upregulated gene 1 (Tug1) is a promising therapeutic target in the progression of diabetic nephropathy (DN), but the molecular basis of its protection remains poorly understood. Here, we generate a triple-mutant diabetic mouse model coupled with metabolomic profiling data to interrogate whether Tug1 interaction with peroxisome proliferator-activated receptor gamma coactivator 1α (PGC1α) is required for mitochondrial remodeling and progression of DN in vivo. We find that, compared with diabetic conditional deletion of Pgc1α in podocytes alone (db/db; Pgc1αPod-f/f), diabetic Pgc1α knockout combined with podocyte-specific Tug1 overexpression (db/db; TugPodTg; Pgc1αPod-f/f) reverses the protective phenotype of …

Do Early-Successional Weeds Facilitate Or Compete With Seedlings In Forest Restoration? Disentangling Abiotic Versus Biotic Factors, Mylen Arias, Rupesh R. Kariyat, Kimberly Wahl-Villarreal, Stephany Mendez, Jesus Chavana, Bradley O. Christoffersen

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

1. Semi-arid forests need cost-effective restoration strategies to address their severe degradation. Tree shelters are often used to minimize abiotic and biotic stress during seedling establishment. We asked if early-successional weeds act as a natural shelter by facilitating native seedlings, contingent on abiotic and biotic stressors and seedling ecological strategy.

2. We conducted a manipulative weed exclusion experiment at a semi-arid site in South Texas targeted for large-scale forest restoration to discern the net effect of weeds on the growth and survival of target thornscrub tree and shrub seedlings. We assessed the roles of contrasting seedling ecological strategies (fast vs. slow growth …

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An Assessment Of Journal Quality Indicators: A Comparative Study Of Selected Medical Journals, Mamatha V, Dr Keshava

Library Philosophy and Practice (e-journal)

The purpose of the study was to assess the correlation between four bibliometric indicators (Impact Factor-IF, Eigenfactor Score-ES, SCImago Journal Rank-SJR, and H5 index) of typical online medical journals were selected from the medical group. Findings from the study evident that in accordance with Pearson’s (r) statistical correlation there is a high significance between four indicators and as per Spearman’s rho statistical correlation there is an association between the three indicators i.e. JIF, SJR, and H5. The above-mentioned indicators are correlated with one a different and it is chiefly true for medical journals when used as communal indicators to estimate …

Pasture Development In Guizhou Province: 25 Years Of New Zealand-China Co‐Operation, M. Philip Rolston, Jishi Xie, T. G. Harvey

IGC Proceedings (1977-2023)

No abstract provided.

Western Beef Development Centre: A Model For Research And Demonstration In Western Canada, Paul G. Jefferson

IGC Proceedings (1977-2023)

No abstract provided.

Integrating Knowledge From Research And Farmer Practice In The Development Of More Productive Forage Systems For Dairy Farms In South‐Eastern Australia, M. O'Kane, G. O'Brien, A. Crawford, Mark S. Paine, D. F. Chapman, J. J. Jacobs

IGC Proceedings (1977-2023)

No abstract provided.

Performance And Locus Of Control Of Small Farmers In Yunnan Province, Alan Mcdermott

IGC Proceedings (1977-2023)

No abstract provided.

Petrel: Platform For Extra And Terrestrial Remote Examination With Lctf, Yoichi Yatsu, Kei Wantanabe, Hiroyuki Kobayashi, Naoki Kawaguchi, Hiroki Hara, Noriatsu Nakamura, Shun Ogata, Kaoru Asaba, Kiyona Miyamoto, Toshihiro Chujo, Saburo Matunaga, Nobuyuki Kawai, Yuji Sakamoto, Kazuhiro Wako, Yoshihide Aoyanagi, Hiroaki Kobayashi, Masashi Uo, Toru Nakano, Takashi Yoshikawa, Eriko Kusunoki, Yu Murata, Norihide Takeyama, Akito Enokuchi, Toshihiko Kimura

Small Satellite Conference

A small satellite ”PETREL” for UV astronomy and remote sensing with ”tunable” multi-spectral cameras conducted by an academia-industrial collaboration is presented. This project was originally proposed by an astronomer who desired a satellite for exploration of explosive objects in ultraviolet. To avoid the earthshine the astronomical observations are scheduled only in the nighttime. To utilize the daytime more electively we conceived a plan of ”satellite sharing” with the industrial collaborators, that can also reduce the developing cost drastically. The daytime mission is spectroscopy that is one of the potential fields in terms of data business, because that can provide chemical …

Hyti: Thermal Infrared Spectroscopy From A 6u Platform, Robert Wright, Paul Lucey, Luke Flynn, Chiara Ferrari-Wong, Andrea Gabrieli, Miguel Nunes, Sarath Gunapala, David Ting, Sir Rafol, Alexander Soibel, Thomas George

Small Satellite Conference

The HyTI (Hyperspectral Thermal Imager) mission, funded by NASA’s Earth Science Technology Office InVEST (In-Space Validation of Earth Science Technologies) program, will demonstrate how high spectral and spatial long-wave infrared image data can be acquired from a 6U CubeSat platform. The mission will use a spatially modulated interferometric imaging technique to produce spectro-radiometrically calibrated image cubes, with 25 channels between 8-10.7 μm, at 13 cm^-1 resolution), at a ground sample distance of ~60 m. The HyTI performance model indicates narrow band NE∆Ts of < 0.3 K. The small form factor of HyTI is made possible via the use of a no-moving-parts Fabry-Perot interferometer, and JPL’s cryogenically-cooled HOT-BIRD FPA technology. Launch is scheduled for no earlier than Fall 2021. The value of HyTI to Earth scientists will be demonstrated via on-board processing of the raw instrument data to generate L1 and L2 products, with a focus on rapid delivery of data regarding volcanic degassing, land surface temperature, and precision agriculture metrics.

In this presentation we will provide an overview of the HyTI measurement approach, the onboard data …

Volume 34, Numbers 1, 2, 3, 4, Fall 1996/Winter 1997/Spring 1997/Summer 1997 Speaker And Gavel

Speaker & Gavel

Complete digitized volume (volume 34, numbers 1-4, Fall 1996/Winter 1997/Spring 1997/Summer 1997) of Speaker & Gavel.

Volume 32, Numbers 1, 2, 3, 4, Fall 1994/Winter 1995/Spring 1995/Summer 1995 Speaker And Gavel

Speaker & Gavel

Complete digitized volume (volume 32, numbers 1-4, Fall 1994/Winter 1995/Spring 1995/Summer 1995) of Speaker & Gavel.

Volume 30, Numbers 1, 2, 3, 4, Fall 1992/Winter 1993/Spring 1993/Summer 1993 Speaker And Gavel

Speaker & Gavel

Complete digitized volume (volume 30, numbers 1-4, Fall 1992/Winter 1993/Spring 1993/Summer 1993) of Speaker & Gavel.

University Week Fall 2021, Rebecca Yantis

University Week

Schedule for the Fall 2021 session of University Week.

LandscanTm‐-Graziers Using Soil Tests And Natural Indicators To Make Better Decisions, Michael J. Keys, B. W. Clements

IGC Proceedings (1977-2023)

No abstract provided.

A Participatory Assessment Of The Development Needs Of Semi‐Sedentary Pastoralists In Kenya, George A. Keya, M. Muga, M. Okoti, A. Adongo, M. Ngutu, D. Mbuvi, F. Wayua, M. Shibia

IGC Proceedings (1977-2023)

No abstract provided.

Research And Extension Experiences On Grassland Protection And Construction (Gpc) Techniques In China, Xiangyang Hou

IGC Proceedings (1977-2023)

No abstract provided.

Engaging Stakeholders To Implement Community‐Based Rangeland Rehabilitation Plans In Southern And Northeastern Ethiopia, G. Gebru, D. Amosha, S. Desta, L. Gizachew, A. Kebede, D. Layne Coppock

IGC Proceedings (1977-2023)

No abstract provided.

Early & Late Erp Responses To L1 & L2 Emotion Words, Brenda Lizeth Guerrero

Theses and Dissertations

The thesis aims to explore bilingual emotion word processing. Participants performed a lexical decision task and decided whether presented letter strings displayed on the computer screen were legal words or nonwords. Stimuli consisted of positive emotion (i.e., hope), negative emotion (i.e., sad), and neutral (i.e., umbrella) words, as well as emotion-laden words (e.g. death, puppy). Reaction time and participant accuracy were collected as behavioral measures. In addition, participants’ electrophysiological responses were recorded. Specifically, the early posterior negativity (EPN) and late positive complex (LPC) components were recorded. Participants’ language dominance was measured using the Bilingual Dominance Scale (BDS) (Dunn & Fox-Tree, …

Episode 6: Kate Mansfield: Turtle Research And Marine Biology, University Of Central Florida

Knights Do That Podcast Transcripts

In this week’s Knights Do That episode, we speak with Davis-Schein Endowed Professor in Conservation Biology Kate Mansfield. She is a marine scientist who is the lab director for the UCF Marine Turtle Research Group and graduate coordinator for UCF's Department of Biology in the College of Sciences.

In this episode, we learn how Mansfield got into this field, some of the coolest things that she’s discovered over the years and what hands-on experiences for her students look like.

Produced by UCF, the podcast highlights students, faculty, staff, administrators and alumni who do incredible things on campus, in the community …

Osteoporosis Implications For The Aging Adult, Grace Alford

Nursing Student Class Projects (Formerly MSN)

This poster describes the pathophysiology, symptoms, implications for care, and treatment of osteoporosis for advanced practice RNs. The research was conducted within health-related databases. The literature review narrowed the search to only include the pathophysiology, interventions, and care for osteoporosis. Literature was restricted to within the past five years. The research showed that osteoporosis reduces mineral density in bones and can be adequately treated within a short amount of time. It is important for nurses and advanced practice providers to be aware of current guidelines, screenings, and treatments for osteoporosis.

New Bs In Environmental Science And Sustainability Will Prepare 21st Century Leaders, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Impacts Of Manipulating Photoperiod On Circadian Rhythms Of Agave Photosynthesis, Robert Hadfield

Undergraduate Honors Theses

Agave uses photoperiod, among other environmental conditions, to time its circadian rhythm of photosynthesis. Two species of Agave (A. americana and A. murpheyi) were tested under two extreme photoperiod conditions (constant light and constant dark) against a normal photoperiod control (12 hours light, 12 hours dark) to identify the impact of abnormal photoperiod on circadian rhythms of Agave photosynthesis. Under constant light conditions, normal oscillations in CO2 gas exchange became unpredictable in duration and amplitude in both species and became very infrequent in A. murpheyi. Under constant dark conditions, net CO2 uptake stabilized at a negative value and oscillations ceased …

Dosimetric Evaluation Of Fixed Jaw And Jaw Tracking Vmat Treatment Plans For Prostate Cancer With Involved Pelvic Nodes, William Rios

Masters Projects

Intro

A mechanical limitation of modern linacs affecting the quality of radiotherapy treatments of large tumor volumes is the travel length of multicollimator leaves. Considering this limitation, research was carried out to evaluate the dosimetric differences between a split-field fixed-jaw volumetric arc radiotherapy (SF-FJ VMAT) technique and a jaw tracking VMAT (JT VMAT) technique for the treatment of prostate cancer with involved lymph nodes.

Methods

Plans for 16 patients treated with the same dose regimen were created using both techniques. Initial JT-VMAT plans were planned with two arcs to encompass the entire tumor volume without jaw restrictions and jaw tracking …