Digital Commons Network^™

Brooks Range Perennial Snowfields : Mapping And Modeling Change In Alaska's Cryosphere, Molly E. Tedesche

Engineering

Perennial snowfields, such as those found in the Brooks Range of Alaska, are a critical component of the cryosphere. They serve as habitat for an array of wildlife, some of which are crucial for rural subsistence hunters. Snowfields also influence hydrology, vegetation, permafrost, and have the potential to preserve valuable archaeological artifacts. In this study, perennial snowfield extents in the Brooks Range are derived from satellite remote sensing, field acquired data, and snowmelt modeling. The remote sensing data are used to map and quantify snow cover area changes across multiple temporal scales, spatial resolutions, and geographic sub-domains. Perennial snowfield classification …

Rheumatic Heart Disease In The United States: Forgotten But Not Gone: Results Of A 10 Year Multicenter Review, Sarah R De Loizaga, Lakshmi R Gokanapudy Hahn, Et Al

Open Access Publications

Background Recent evaluation of rheumatic heart disease (RHD) mortality demonstrates disproportionate disease burden within the United States. However, there are few contemporary data on US children living with acute rheumatic fever (ARF) and RHD. Methods and Results Twenty-two US pediatric institutions participated in a 10-year review (2008-2018) of electronic medical records and echocardiographic databases of children 4 to 17 years diagnosed with ARF/RHD to determine demographics, diagnosis, and management. Geocoding was used to determine a census tract-based socioeconomic deprivation index. Descriptive statistics of patient characteristics and regression analysis of RHD classification, disease severity, and initial antibiotic prescription according to community …

Great Plains Population Of The Dwarf Shrew (Sorex Nanus), With A Record From Nebraska, Russell A. Benedict, Zachary P. Roehrs, Thomas E. Labedz, Hugh H. Genoways

Western North American Naturalist

A diminutive shrew from Sioux County, Nebraska, is shown to be the first state record for the dwarf shrew, Sorex nanus. This specimen appears to be a member of a dwarf shrew population occurring on the Great Plains in the vicinity of the Black Hills in western South Dakota, eastern Wyoming, and southeastern Montana, but not within the Black Hills proper. Other populations of this species occur in montane environments in the Rocky Mountains, from Montana south through Wyoming, Colorado, New Mexico, Utah, and some isolated mountains in Arizona. The arid grassland habitats inhabited by the Great Plains population …

Predicting Dominance Of Sand Transport By Waves, Tides, And Their Interactions On Sandy Continental Shelves: Dataset, Erin Victoria King, Daniel Conley, Gerd Masselink, Nicoletta Leonardi

Faculty of Science and Engineering Datasets

This is the dataset accompanying the article of King et al. (2021) by the same title in the Journal of Geophysical Research: Oceans. This dataset contains data in MATLAB .mat format for the data presented in the above paper, including trained k-Nearest Neighbour classifiers for dominant sand transport mode and magnitude. Citation KIng, E. V. et al. (2021). Predicting Dominance of Sand Transport by Waves, Tides, and Their Interactions on Sandy Continental Shelves: Dataset. PEARL Research Repository http://dx.doi.org/10.24382/5004

The Histories Of Hivs : The Emergence Of The Multiple Viruses That Caused The Aids Epidemics, William H. Schneider

Ohio University Press Open Access Books

This new collection of essays on HIV viruses spans disciplines to topple popular narratives about the origins of the AIDS pandemic and the impact of the disease on public health policy.

With a death toll in the tens of millions, the AIDS pandemic was one of the worst medical disasters of the past century. The disease was identified in 1981, at the height of miraculous postwar medical achievements, including effective antibiotics, breakthrough advances in heart surgery and transplantations, and cheap, safe vaccines—smallpox had been eradicated just a few years earlier. Arriving as they did during this era of confidence in …

Electrochemical Micro-Aptasensors For Exosome Detection Based On Hybridization Chain Reaction Amplification, Wenfen Zhang, Zhenhua Tian, Shujie Yang, Joseph Rich, Shuaiguo Zhao, Mikael Klingeborn, Po-Hsun Huang, Zhishang Li, Alexander Stout, Quinn Murphy, Edward Patz, Shusheng Zhang, Guozhen Liu, Tony Jun Huang

Faculty Publications

Exosomes are cell-derived nanovesicles that have recently gained popularity as potential biomarkers in liquid biopsies due to the large amounts of molecular cargo they carry, such as nucleic acids and proteins. However, most existing exosome-based analytical sensing methods struggle to achieve high sensitivity and high selectivity simultaneously. In this work, we present an electrochemical micro-aptasensor for the highly sensitive detection of exosomes by integrating a micropatterned electrochemical aptasensor and a hybridization chain reaction (HCR) signal amplification method. Specifically, exosomes are enriched on CD63 aptamer-functionalized electrodes and then recognized by HCR products with avidin-horseradish peroxidase (HRP) attached using EpCAM aptamers as …

Bridging Expert Knowledge And Fisheries Data To Inform Assessment And Management Of Rockfishes In The Gulf Of Alaska, Jesse Gordon

Fisheries

Over the past few decades, nearshore rockfishes (Sebastes spp.) have experienced increased pressure from multiple fisheries throughout the Gulf of Alaska. The unique life history traits of rockfishes pose a host of challenges that make them difficult to monitor and vulnerable to overfishing. Rockfishes are economically and culturally important to coastal communities in the Gulf of Alaska. Therefore, the inclusion of fishers' knowledge in rockfish assessment and management will help to address biological goals and meet the needs of a growing fishery. This thesis examines the recent history and current management issues in nearshore rockfish fisheries in the Gulf of …

Ocean And Stream Ecology Of Adult Hatchery And Wild Pink Salmon, Julia Mcmahon

Fisheries

In this thesis I investigate potential interactions of hatchery and wild pink salmon (Oncorhynchus gorbuscha) at sea and on the spawning grounds, in the context of the ecological and economic importance of modern Alaskan hatcheries. Although hatchery and wild salmon are known to interact, the nature and outcome of those interactions remain unclear. Here, I identify potential mechanisms of competition and hatchery salmon fitness with two datasets from Prince William Sound, Alaska, home to the largest pink salmon hatchery program in the world. First, I compared fitness-related traits such as body length, return timing, instream lifespan, and egg retention between …

Phylogenetic And Drug-Resistance Analysis Of Hiv-1 Sequences From An Extensive Paediatric Hiv-1 Outbreak In Larkana, Pakistan, Syed Hani Abidi, George Makau Nduva, Dilsha Siddiqui, Wardah Rafaqat, Syed Faisal Mahmood, Amna Rehana Siddiqui, Apsara Ali, Aneeta Hotwani, Rashida Abbas Ferrand, Fatima Mir

Department of Biological & Biomedical Sciences

Introduction: In April 2019, an HIV-1 outbreak among children occurred in Larkana, Pakistan, affecting more than a thousand children. It was assumed that the outbreak originated from a single source, namely a doctor at a private health facility. In this study, we performed subtype distribution, phylogenetic and drug-resistance analysis of HIV-1 sequences from 2019 outbreak in Larkana, Pakistan.
Methods: A total of 401 blood samples were collected between April-June 2019, from children infected with HIV-1 aged 0-15 years recruited into a case-control study to investigate the risk factors for HIV-1 transmission. Partial HIV-1 pol sequences were generated from 344 blood …

College Of Education News, Georgia Southern University

College of Education: News & Publications (2003-2023)

• Call for presenters for 2021 Trauma Informed Education Symposium
• Three faculty awarded research assistance in competitive selection process
• College of Education 2021 Jack Miller Award winners announced
• Georgia Southern education faculty receives 2021 Inspiring Programs in STEM Award from INSIGHT Into Diversity

Mechanistic Investigation Of Neuropeptide S-Nitrosylation By Nitric Oxide Moieties: A Kinetic And Thermodynamic Approach, Vusumuzi Leroy Sibanda

Dissertations and Theses

This dissertation focuses on providing quantitative insights regarding kinetic, thermodynamic and mechanistic parameters of neuropeptide S-nitrosylation by nitrous acid (HNO₂), peroxynitrite (ONOO^-) and S-nitroso-N-acetyl-D,L-penicillamine (SNAP) to produce S-nitrosothiols (SNOs). Peptide thiol stability and the formation of SNOs from neuropeptides; arginine vasopressin (AVP), somatostatin-14 (SST-14) and urotensin II (U-II) was studied. Investigations into the effects of temperature, copper chelators and pH on peptide thiol autoxidation show that AVP, SST-14 and U-II thiols have half-lives of 30, 44 and 28.2 mins respectively at physiologically relevant temperature and pH in the absence of metal chelators. Target peptide thiols were …

Family & Friends, Volume 7, Number 1

Family & Friends, 1998-2006

Patricia Pair, Publisher. Anita C. Moyt, Managing Editor. Anthony Hardaway, Multi-Cultural Affairs Editor. Contributors: J. Shane Wilson, Laine McNeil, Rex Wockner, John Crossen, Kevin Shaw, Jim Easter, Katie Hiestand, Laer Gib Retae, Wansel Greenberry.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Family & Friends, Volume 7, Number 3

Family & Friends, 1998-2006

Patricia Pair, Publisher. Anita C. Moyt, Managing Editor. Anthony Hardaway, Multi-Cultural Affairs Editor. Contributors: J. Shane Wilson, Laine McNeil, Rex Wockner, John Crossen, Kevin Shaw, Jim Easter, Katie Hiestand, Laer Gib Retae, Wansel Greenberry.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.

Rheumatic Heart Disease In The United States: Forgotten But Not Gone: Results Of A 10 Year Multicenter Review., Sarah R. De Loizaga, Lindsay Arthur, Bhawna Arya, Brian Beckman, Wubishet Belay, Cole Brokamp, Nak Hyun Choi, Sean Connolly, Soham Dasgupta, Tavenner Dibert, Marylou M. Dryer, Lakshmi R. Gokanapudy Hahn, Elizabeth Anne Greene, Daphney Kernizan, Omar Khalid, Jennifer Klein, Ryan Kobayashi, Subhrajit Lahiri, Raymond P. Lorenzoni, Andrea Otero Luna, Jennifer A. Marshall, Theodore Millette, Lily Moore, Babu Muhamed, Meghna Murali, Kinjal Parikh, Amy Sanyahumbi, Divya Shakti, Elizabeth Stein, Sanket Shah, Hannah Wilkins, Mcallister Windom, Scott Wirth, Meghan Zimmerman, Andrew F. Beck, Nicholas Ollberding, Craig Sable, Andrea Beaton

Manuscripts, Articles, Book Chapters and Other Papers

Background Recent evaluation of rheumatic heart disease (RHD) mortality demonstrates disproportionate disease burden within the United States. However, there are few contemporary data on US children living with acute rheumatic fever (ARF) and RHD. Methods and Results Twenty-two US pediatric institutions participated in a 10-year review (2008-2018) of electronic medical records and echocardiographic databases of children 4 to 17 years diagnosed with ARF/RHD to determine demographics, diagnosis, and management. Geocoding was used to determine a census tract-based socioeconomic deprivation index. Descriptive statistics of patient characteristics and regression analysis of RHD classification, disease severity, and initial antibiotic prescription according to community …

Favorable Outcomes With Reduced Steroid Use In Juvenile Dermatomyositis, Amir B Orandi, Lampros Fotis, Jamie Lai, Hallie Morris, Andrew J White, Anthony R French, Kevin W Baszis

2020-Current year OA Pubs

BACKGROUND: High-intensity glucocorticoid regimens are commonly used to induce and maintain remission in Juvenile Dermatomyositis but are associated with several adverse side-effects. Evidence-based treatment guidelines from North American and European pediatric rheumatology research societies both advocate induction with intravenous pulse steroids followed by high dose oral steroids (2 mg/kg/day), which are then tapered. This study reports the time to disease control with reduced glucocorticoid dosing.

METHODS: We retrospectively reviewed the records at a single tertiary-care children's hospital of patients diagnosed with Juvenile Dermatomyositis between 2000 and 2014 who had a minimum of 2 years of follow-up. The primary outcome measure …

Reins: Genotype-Phenotype Correlations In Neurofibromatosis And Their Potential Clinical Use, Clemens O. Hanemann

Peninsula Medical School

No abstract provided.

Breeding Rootstocks For Fruit Trees In Palestine: Status And Prospective Toward Future Climate Change Scenarios, Rezq Basheer, Fatina Hawamdeh, Abdul Jalil Hamdan

Hebron University Research Journal-A (Natural Sciences) - (مجلة جامعة الخليل للبحوث- أ (العلوم الطبيعيه

This review characterizes, identifies and presents remarks of breeding rootstocks in Palestine. It’s based upon a survey of the rootstocks that have been used along decades of breeding and grafting of local and introduced cultivars. All for acclimatization for hard conditions that confront fruit trees. It also proposes some expected promising rootstocks that might suit the climate change and whatever affected by it of biotic and abiotic stresses in the area. Obviously, this review discusses the advantages of the current confirmed rootstocks that are compatible with most of the species of the popular trees. It also pointed out to inadequate …

Comparing A Dss And Farmers' Decisions For Rangeland Management In Semi Arid Namibia, D. F. Joubert, I. Zimmermann, J. Fendler, H. Winschiers, F. P. Graz

IGC Proceedings (1977-2023)

No abstract provided.

Building A Shared Diagnosis Of Land Use Within A Multi‐Stakeholder Platform In A Pastoral Mountainous Area In The Western Pyrenees, N. Girard, D. Magda, P. Gascouat, D. Lassalle

IGC Proceedings (1977-2023)

No abstract provided.

Atg8 Is Conserved Between Saccharomyces Cerevisiae And Psychrophilic, Polar-Collected Fungi, B. J. Ivory, H. M. Smith, E. Cabrera, M. R. Robinson, J. T. Sparks, A. Solem, J. I. Ishihara, H. Takahashi, M. Tsuji, V. A. Segarra

Osteopathic Medicine, Jerry M. Wallace School of

No abstract provided.

A Nation And Culture's Fight For Survival: How The Existing Indian Family Exception Renders Icwa Inapplicable, Keely Kleven

Nebraska Law Bulletin (Selected Issues)

The Indian Child Welfare Act (ICWA) was enacted to curtail the removal of Indian children from their tribes and families by allowing tribes to have jurisdiction over custody proceedings involving Indian children; it ensured the security of tribes by allowing them to pass Indian culture down from one generation to the next. The chances of Indian survival, as noted by Calvin Isaac, are significantly reduced when Indian children are raised in non-Indian homes or denied exposure to their heritage. Although some states have complied with the spirit of the ICWA, other states have created the existing Indian family (EIF) exception …

School Choice In Tennessee: A Violation Of The State Constitutional Right To A Substantially Equal Education, Emma Knapp

Lincoln Memorial University Law Review Archive

Most states have experimented with various versions of school choice over the past several years. While a federal right to education is not recognized, all fifty state constitutions provide some variation of an education clause, guaranteeing a state constitutional right to education. In Tennessee, satisfaction of the state constitutional right to education requires substantially equal educational opportunities for all students across the state. Despite this constitutional mandate, students in public schools across the state of Tennessee experience vast disparities in educational opportunities. Litigation is currently pending before the Tennessee Supreme Court regarding the constitutionality of the Tennessee Education Savings Account …

Attack Transferability Against Information-Theoretic Feature Selection, S. Gupta, R. Golota, Gregory Ditzler

Henry M. Rowan College of Engineering Departmental Research

Machine learning (ML) is vital to many application-driven fields, such as image and signal classification, cyber-security, and health sciences. Unfortunately, many of these fields can easily have their training data tampered with by an adversary to thwart an ML algorithm’s objective. Further, the adversary can impact any stage in an ML pipeline (e.g., preprocessing, learning, and classification). Recent work has shown that many models can be attacked by poisoning the training data, and the impact of the poisoned data can be quite significant. Prior works on adversarial feature selection have shown that the attacks can damage feature selection (FS). Filter …

Schenk To Use Desert Flowers To Pursue An Unanswered Question About Macroevolution, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

A Novel Treatment Strategy For Lapatinib Resistance In A Subset Of Her2-Amplified Gastric Cancer., Gang Ning, Qihui Zhu, Wonyoung Kang, Hamin Lee, Leigh Maher, Yun-Suhk Suh, Michael Michaud, Mayerlin Silva, Jee Young Kwon, Chengsheng Zhang, Charles Lee

Faculty Research 2021

BACKGROUND: Gastric cancer (GC) is one of the leading causes of cancer-related deaths worldwide. Human epidermal growth factor receptor 2 (HER2) amplification occurs in approximately 13-23% of all GC cases and patients with HER2 overexpression exhibit a poor prognosis. Lapatinib, a dual EGFR/HER2 tyrosine kinase inhibitor, is an effective agent to treat HER2-amplified breast cancer but it failed in gastric cancer (GC) clinical trials. However, the molecular mechanism of lapatinib resistance in HER2-amplified GC is not well studied.

METHODS: We employed an unbiased, genome-scale screening with pooled CRISPR library on HER2-amplified GC cell lines to identify genes that are associated …

From Green Pastures To Scorched Earth: German Environmentalism And Ecology, C. 1800s-1945, Santiago G. Lozada

Student Theses

Nature Conservation in Germany from The Second German Empire until Nazi Germany

Development Of The Biohybrid Assay: Combining Primary Human Vascular Smooth Muscle Cells And Blood To Measure Vascular Calcification Propensity, Armand M G Jaminon, Asim C Akbulut, Niko Rapp, Rafael Kramann, Erik A L Biessen, Lieve Temmerman, Barend Mees, Vincent Brandenburg, Robert Dzhanaev, Willi Jahnen-Dechent, Juergen Floege, Jouni Uitto, Chris P Reutelingsperger, Leon J Schurgers

Department of Dermatology and Cutaneous Biology Faculty Papers

BACKGROUND: Vascular calcification is an active process that increases cardiovascular disease (CVD) risk. There is still no consensus on an appropriate biomarker for vascular calcification. We reasoned that the biomarker for vascular calcification is the collection of all blood components that can be sensed and integrated into a calcification response by human vascular smooth muscle cells (hVSMCs).

METHODS: We developed a new cell-based high-content assay, the BioHybrid assay, to measure in vitro calcification. The BioHybrid assay was compared with the o-Cresolphthalein assay and the T50 assay. Serum and plasma were derived from different cohort studies including chronic kidney disease (CKD) …

08-16-2021 Railey Rumohr Named Paula Jeanne Horsburgh Memorial Scholar At Swosu, Southwestern Oklahoma State University

THE BARK ARCHIVE 2021

No abstract provided.

Legal Barriers To Accessing Safe Abortion Services In India: A Fact Finding Study, Aparna Chandra, Mrinal Satish, Shreya Shree, Mini Saxena

Books

No abstract provided.

College Of Arts & Sciences Welcome Locations, Aug 21, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.