Digital Commons Network^™

Glaciermap: A Virtual Opportunity To Explore The Andes’ Vanishing Glaciers, Caroline Clason, Sally Rangecroft, Gina Kallis, Shaun Lewin, Tom Mullier

School of Nursing and Midwifery

For many of us, when we think about glaciers, we might imagine cold, icy polar environments such as the Arctic or Antarctica and their associated characteristic fauna. However, the existence of glaciers is not limited to high latitudes, with numerous glaciers also found close to, or even within, the Tropics, where elevation is high enough for snow and ice to persist year-round. Indeed, high mountain regions at lower latitudes, such as the South American Andes and the Asian Himalayas, are home to many hundreds of glaciers and these glaciers provide important water resources for local populations. These mountain glaciers act …

Toward A Methodology For Evaluating Dna Variants In Nuclear Families, Dustin B. Miller, Reid Robison, Stephen Piccolo

Faculty Publications

The genetic underpinnings of most pediatric-cancer cases are unknown. Population-based studies use large sample sizes but have accounted for only a small proportion of the estimated heritability of pediatric cancers. Pedigree-based studies are infeasible for most human populations. One alternative is to collect genetic data from a single nuclear family and use inheritance patterns within the family to filter candidate variants. This approach can be applied to common and rare variants, including those that are private to a given family or to an affected individual. We evaluated this approach using genetic data from three nuclear families with 5, 4, and …

The Cover Crop Seed Industry: An Indiana Case Study, John C. Tyndall, Adriana Valcu-Lisman, Melanie Bogert, Abigail Zobrodsky

Journal of Applied Farm Economics

Winter cover crops are plants used to protect soils during the period between the harvest and establishment of cash crops such as corn and soybeans, effectively providing farm fields with perennial cover. The total cost of cover crops varies considerably from site to site and year to year, yet the single costliest aspect of using cover crops is the cost of seed. Seed cost also tends to be the most volatile component of the cost of cover crop use, subject to complex supply dynamics associated with producing viable seed, storage capacity, and unpredictable regional demand. We conducted a survey of …

The Role Of Farmer Heterogeneity In Nutrient Management: A Farm-Level Analysis, Hua Wang, Naveen Adusumilli, Daniel Fromme, Keith Shannon

Journal of Applied Farm Economics

Understanding farmer heterogeneity regarding nutrient management decisions is crucial for the success of any nonpoint source pollution prevention programs. Data from a farm- level experiment of cover crops in corn production were used in the Stochastic Efficiency with Respect to a Function framework to examine preference for nitrogen strategies over a range of risk aversion levels. We show the highest net return and certainty equivalent to the consideration of N supplied by cover crops. The results provide insights into policy discussions about the level of conservation incentives and plans that offer solutions to mitigate nonpoint source pollution.

Assessment Of Student-Faculty Choices On Digital Resources: A Case Study Of Haryana Agricultural University, Hisar, Kulveen Kaur Dr., Kulveen Kaur Dr

Library Philosophy and Practice (e-journal)

Universities are pioneer in adopting digital platform as a new mainstream. The inclusion of digital resources in university libraries has steered the education system deeper towards digital learning. To gather insight into student-faculty choices on digital resources, a survey on 183 subjects’ of Haryana Agricultural University, Hisar was conducted focusing on major aspects related to use of digital resources. Student-faculty awareness and frequency of using digital resources; their preferences towards different digital resources; reasons for their preferences as well the possibilities of libraries getting print less in future. It was discovered that digital media has deep impact on student-faculty choices. …

Tree Competition Reduces Cattle Growth Rates In Eucalypt Woodlands Of Queensland, T. J. Hall, J. R. Douglas

IGC Proceedings (1977-2023)

The wiregrass/bluegrass (Aristida/Bothriochloa) native pasture community in Eucalypt woodlands is a major cattle producing resource in Queensland. The effects of poplar box tree (Eucalyptus populnea) competition (at 5 m²/ha tree basal area) and grazing pressure on pastures and on growth of Brahman-cross steers were measured in a grazing experiment. Treatments were 2 tree competition levels (live trees or clearing) by 3 grazing pressures (low - 25%, medium - 50% and high - 75% utilisation of annual pasture growth). Pasture yield and pasture foliage cover increased for 3 years from the reduction in tree competition …

Perloline, The Forgotten Plant Alkaloid, L. P. Bush

IGC Proceedings (1977-2023)

Perloline, a biologically active plant alkaloid, accumulated in vegetative tissue of tall fescue during the summer months. Perloline content increased with increased available nitrogen and light. Total perloline accumulation was greatest with NO₃-N fertilizer, but greatest perloline content per unit of dry wt was measured with NH₄-N. In mature plants greatest perloline accumulation occurred in the leaves and immature inflorescences, but was not detected in the seed. Leaves of meadow fescue contained the greatest amounts of perloline, tall fescue was intermediate and giant fescue, and ryegrasses and yellow foxtail had low amounts of the alkaloid. Tryptophan …

Bloat In Ruminants: The Cell Rupture Hypothesis, B. P. Berg, T. A. Mcallister, K.-J. Cheng

IGC Proceedings (1977-2023)

An alfalfa (Medicago sativa L.) cultivar with a low initial rate of digestion (LIRD), AC Grazeland B, was developed to test the hypothesis that the rate of cell rupture was a cause of frothy bloat in cattle or sheep. The amount of cell wall increases and digestibility declines as plants mature. Thus the cell rupture theory also predicts that the bloat potential of alfalfa is related to maturity. This study compared the digestibility of cell walls (NDF) in LIRD cultivars with that of a standard, Beaver, in relation to maturity and bloat incidence. Fresh alfalfa was fed to wethers …

Effect Of Storage Time And Temperature On Recovery Of Synergistes Jonesii From Rumen Fluid And Feces, W. M. Andrew, M. J. Williams, M. J. Allison, C. C. Chase Jr., C. G. Chambliss, R. S. Kalmbacher, W. E. Kunkle

IGC Proceedings (1977-2023)

Synergistes jonesii is a rumen bacterium that degrades 3,4-dihydroxypyridine (3,4 DHP), the toxic breakdown product of mimosine in leucaena (Leucaena leucocephala). Fecal culture is the most practical way to determine S. jonesii presence in zoological ruminants, particularly if feces can be collected from night penning facilities. Fresh rumen fluid and fecal or fecal slurry (sheep [Ovis spp.] only, 1:4 wt to vol. feces and culture media) from cattle (Bos spp.) and sheep, known to be colonized by S. jonesii, were subjected various storage times (0, 6, 12, and 24 h) and temperatures (5, 23, and …

Intein Inhibitors As Novel Antimicrobials: Protein Splicing In Human Pathogens, Screening Methods, And Off-Target Considerations, Diana A. Wall, Chunyu Wang, Kenneth Mills, Christopher W. Lennon

Faculty & Staff Research and Creative Activity

Protein splicing is a post-translational process by which an intervening polypeptide, or intein, catalyzes its own removal from the flanking polypeptides, or exteins, concomitant with extein ligation. Although inteins are highly abundant in the microbial world, including within several human pathogens, they are absent in the genomes of metazoans. As protein splicing is required to permit function of essential proteins within pathogens, inteins represent attractive antimicrobial targets. Here we review key proteins interrupted by inteins in pathogenic mycobacteria and fungi, exciting discoveries that provide proof of concept that intein activity can be inhibited and that this inhibition has an effect …

October 7, 2021, Ohio University Board Of Trustees Meeting Minutes, Ohio University Board Of Trustees

Board of Trustees Meeting Minutes

Meeting minutes document the activities of Ohio University's Board of Trustees.

Bryant University Day Of Understanding, Justice Begins With Us, Office Of Institutional Diversity, Equity, And Inclusion

Day of Understanding Programs

No abstract provided.

Cellular Origins Of Egfr-Driven Lung Cancer Cells Determine Sensitivity To Therapy, Fan Chen, Jinpeng Liu, Robert M. Flight, Kassandra J. Naughton, Alexsandr Lukyanchuk, Abigail R Edgin, Xiulong Song, Haikuo Zhang, Kwok-Kin Wong, Hunter N. B. Moseley, Chi Wang, Christine F. Brainson

Toxicology and Cancer Biology Faculty Publications

Targeting the epidermal growth factor receptor (EGFR) with tyrosine kinase inhibitors (TKIs) is one of the major precision medicine treatment options for lung adenocarcinoma. Due to common development of drug resistance to first- and second-generation TKIs, third-generation inhibitors, including osimertinib and rociletinib, have been developed. A model of EGFR-driven lung cancer and a method to develop tumors of distinct epigenetic states through 3D organotypic cultures are described here. It is discovered that activation of the EGFR T790M/L858R mutation in lung epithelial cells can drive lung cancers with alveolar or bronchiolar features, which can originate from alveolar type 2 (AT2) cells …

Systematic Review Of Polyherbal Combinations Used In Metabolic Syndrome, Amber Hanif Palla, Faridah Amin, Bilqees Fatima, Arooj Shafiq, Najeeb Ur Rehman, Ikram Ul Haq, Anwar-Ul-Hassan Gilani

Department of Biological & Biomedical Sciences

Background: Metabolic syndrome (MetS) is a multifactorial disease, whose main stay of prevention and management is life-style modification which is difficult to attain. Combination of herbs have proven more efficacious in multi-targeted diseases, as compared to individual herbs owing to the "effect enhancing and side-effect neutralizing" properties of herbs, which forms the basis of polyherbal therapies This led us to review literature on the efficacy of herbal combinations in MetS.
Methods: Electronic search of literature was conducted by using Cinnahl, Pubmed central, Cochrane and Web of Science, whereas, Google scholar was used as secondary search tool. The key words used …

An Examination Of The Relationship Between Eating Competence And Biopsychosocial Factors In Adults With Metabolic Syndrome, Jenna Hickey

Theses

Background: An association between eating competence and bioclinical factors for healthy adults has been identified. However, no research has been conducted into the association of ecSI 2.0TM scores and biopsychosocial measures for adults with metabolic syndrome. Purpose: To examine the congruence between eating competence and biopsychosocial measures at baseline and post-intervention in individuals with metabolic syndrome. Methods: Self report surveys administered to participants: Satter Eating Competence Inventory (ecSI 2.0TM), Short Form Health Survey Mental Health and Vitality scales(SF-36 MH and VT), Perceived Stress Scale (PSS), Patient Health Questionnaire – 8 (PHQ-8). Bioclinical measures: HDL cholesterol, triglycerides, blood glucose, BMI, and …

October 7, 2021, Caa

Minutes

No abstract provided.

Enviromic Assembly Increases Accuracy And Reduces Costs Of The Genomic Prediction For Yield Plasticity In Maize, Germano Costa-Neto, Jose Crossa, Roberto Fritsche-Neto

Faculty Publications

Quantitative genetics states that phenotypic variation is a consequence of the interaction between genetic and environmental factors. Predictive breeding is based on this statement, and because of this, ways of modeling genetic effects are still evolving. At the same time, the same refinement must be used for processing environmental information. Here, we present an “enviromic assembly approach,” which includes using ecophysiology knowledge in shaping environmental relatedness into whole-genome predictions (GP) for plant breeding (referred to as enviromic-aided genomic prediction, E-GP). We propose that the quality of an environment is defined by the core of environmental typologies and their frequencies, which …

Evaluating Otter Reintroduction Outcomes Using Genetic Spatial Capture-Recapture Modified For Dendritic Networks, Sean M. Murphy, Jennifer R. Adams, Lisette P. Waits, John J. Cox

Forestry and Natural Resources Faculty Publications

Monitoring the demographics and genetics of reintroduced populations is critical to evaluating reintroduction success, but species ecology and the landscapes that they inhabit often present challenges for accurate assessments. If suitable habitats are restricted to hierarchical dendritic networks, such as river systems, animal movements are typically constrained and may violate assumptions of methods commonly used to estimate demographic parameters. Using genetic detection data collected via fecal sampling at latrines, we demonstrate applicability of the spatial capture–recapture (SCR) network distance function for estimating the size and density of a recently reintroduced North American river otter (Lontra canadensis) population in …

Adolescent Girls And Covid-19: Mapping The Evidence On Interventions, Sarah Blake, Miriam Temin, Tara Abularrage, Nihal Said

Poverty, Gender, and Youth

With the COVID-19 crisis continuing to evolve, evidence on the effectiveness of short-term emergency-oriented responses and long-term mitigation strategies is expanding but still limited. There are, and will continue to be, substantial evidence gaps on programming to address risk across outcomes of importance to adolescent girls. More evidence is needed to slow the risks posed by the pandemic for this subpopulation, which can help guide gender- and age-responsive prevention and impact mitigation investments. Evidence from approaches delivered in other unstable contexts may offer important lessons for decision-making in the current context. Recognizing this, the Population Council conducted a structured review …

Hawks' Herald -- Oct. 7, 2021, Roger Williams University

Hawk's Herald

No abstract provided.

Newsroom, Georgia Southern University

Newsroom (2006-2023)

• Georgia Southern University to host 2021 Active Minds Send Silence Packing® Exhibit
• Checo Colón-Gaud receives inaugural Leadership Award from Society for Freshwater Science

Daily Eastern News: October 07, 2021, Eastern Illinois University

October

No abstract provided.

Receiver Apprehension & Listener Style Retention, Karlene T. Clark

Librarian Posters and Presentations

Receiver apprehension is the anxiety patrons feel when approaching someone for help. There are different types of ways in which people process information, some of which can be a detriment to the person hoping to learn something or just have a question answered. This presentation looks at the different styles of listeners and how librarians can utilize this knowledge to better meet the needs of patrons coming to the reference desk for assistance.

Novel Insights Into Negative Pressure Wound Healing From An In Situ Porcine Perspective, Jacob G. Hodge, Ashley L. Pistorio, Christopher A. Neal, Hongyan Dai, Jennifer G. Nelson-Brantley, Molly E. Steed, Richard A. Korentager, David S. Zamierowski, Adam J. Mellott

School of Medicine Faculty Research

Negative pressure wound therapy (NPWT) is used clinically to promote tissue formation and wound closure. In this study, a porcine wound model was used to further investigate the mechanisms as to how NPWT modulates wound healing via utilization of a form of NPWT called the vacuum-assisted closure. To observe the effect of NPWT more accurately, non-NPWT control wounds containing GranuFoam™ dressings, without vacuum exposure, were utilized. In situ histological analysis revealed that NPWT enhanced plasma protein adsorption throughout the GranuFoam™, resulting in increased cellular colonization and tissue ingrowth. Gram staining revealed that NPWT decreased bacterial dissemination to adjacent tissue with …

The Colby Echo (2021-10-07), Colby College

The Colby Echo

Published by the students of Colby College since 1877, The Colby Echo is the weekly, editorially independent student-run newspaper of Colby College in Waterville, Maine. Published monthly, 1877-1886; semi-monthly, 1886-1897; and weekly, during the academic year, 1898-present.

Recent Applications Of Quantitative Systems Pharmacology And Machine Learning Models Across Diseases, Sara Sadat Aghamiri1, Rada Amin, Tomáš Helikar

Department of Biochemistry: Faculty Publications

Quantitative systems pharmacology (QSP) is a quantitative and mechanistic platform describing the phenotypic interaction between drugs, biological networks, and disease conditions to predict optimal therapeutic response. In this meta-analysis study, we review the utility of the QSP platform in drug development and therapeutic strategies based on recent publications (2019–2021). We gathered recent original QSP models and described the diversity of their applications based on therapeutic areas, methodologies, software platforms, and functionalities. The collection and investigation of these publications can assist in providing a repository of recent QSP studies to facilitate the discovery and further reusability of QSP models. Our review …

Assemblages Of Acari In Shallow Burials: Mites As Markers Of The Burial Environment, Of The Stage Of Decay And Of Body‑Cadaver Regions, Jas K. Rai, Brian J. Pickles, M. Alejandra Perotti

Harold W. Manter Laboratory of Parasitology: Library Materials

The burial of a cadaver results in reduced arthropod activity and disruptions in colonisation patterns. Here, the distribution and diversity of mite taxa was studied across decomposition stages of shallowly buried pig carcasses (Sus scrofa domesticus). In total 300 mites (88 species) were collected from three pig shallow graves compared to 129 mites (46 species) from control (bare) soil samples at the same depth. A successional pattern of Acari higher taxa and families was observed, and species richness and biodiversity fluctuated throughout decomposition, whereas active decay showed the greatest biodiversity. Mesostigmata mites were the most abundant in ‘cadaver …

A Neutrosophic Folding On A Neutrosophic Fundamental Group, M. Abu-Saleem

Neutrosophic Sets and Systems

No abstract provided.

Free-Floating Immunostaining Of Mouse Brains, Longlong Tu, Nan Zhang, Kristine M Conde, Jonathan C Bean, Chunmei Wang, Yong Xu

Children’s Nutrition Research Center Staff Publications

Immunohistochemical staining of mouse brains is a routine technique commonly used in neuroscience to investigate central mechanisms underlying the regulation of energy metabolism and other neurobiological processes. However, the quality, reliability, and reproducibility of brain histology results may vary among laboratories. For each staining experiment, it is necessary to optimize the key procedures based on differences in species, tissues, targeted proteins, and the working conditions of the reagents. This paper demonstrates a reliable workflow in detail, including intra-aortic perfusion, brain sectioning, free-floating immunostaining, tissue mounting, and imaging, which can be followed easily by researchers in this field.

Also discussed are …

Using Bibliometrics To Evaluate Outcomes And Influence Of Translational Biomedical Research Centers, Kristine M. Bragg, Gwen C. Marchand, Jonathan C. Hilpert, Jeffrey L. Cummings

Educational Psychology, Leadership, and Higher Education Faculty Research

Introduction. Federal grant funding to support infrastructure development of translational biomedical research centers is a form of public health intervention. Establishing rigorous methods for measuring center success and outcomes is essential to justify continued funding. Methods. Bibliometric data compiled from a 5-year funding cycle of a neurodegeneration and translational neuroscience research center was analyzed using the package bibliometrix for open source software R and the NIH-developed research tool iCite. Results. The research team and their collaborators (n=485) produced 157 grant-citing publications from 2015-2020. The science was produced by small research teams clustered around three main communities of topics: Alzheimer's Disease, …