Digital Commons Network^™

Integrating Dynamic Systems Theory And City As Text™ Framework: In-Depth Reflections On ‘Lens’, Ron Weerheijm, Patricia Vuijk, Bernice Braid

National Collegiate Honors Council Monographs: Chapters

City as Text™ provides a semi-structured learning environment in which small groups of people are challenged to examine parts of a city through “mapping, observing, interpreting, analyzing, reflecting.” In 2014, I (Ron Weerheijm) attended a City as Text (CAT) Faculty Institute in Lyon. During an early session on the hills overlooking the eastern part of Lyon, our group observed a Basilique, the Notre Dame de Fourvière (1872–1884; interior finished 1964). Having a degree in architecture, I looked at this church from architectural and historical viewpoints. I was puzzled. In a quick scan, many different styles competed for my attention, hurting …

Mapping The Current Landscape Of Research Library Engagement With Emerging Technologies In Research And Learning: Final Report, Sarah Lippincott, Mary Lee Kennedy, Clifford Lynch, Scout Calvert, Jocelyn Cozzo

University of Nebraska-Lincoln Libraries: Faculty Publications

The generation, dissemination, and analysis of digital information is a significant driver, and consequence, of technological change. As data and information stewards in physical and virtual space, research libraries are thoroughly entangled in the challenges presented by the Fourth Industrial Revolution:1 a societal shift powered not by steam or electricity, but by data, and characterized by a fusion of the physical and digital worlds.2 Organizing, structuring, preserving, and providing access to growing volumes of the digital data generated and required by research and industry will become a critically important function. As partners with the community of researchers and scholars, research …

Timber Talk, Vol. 59, No. 2, June 2021

Timber Talk: Nebraska Forest Industry Newsletter

Timber Talk, Vol. 59, No.2, June 2021

To Teach As We Are Known: The ‘Heart And Soul’ Labor Of Teacher Educators Of Color Working In Pwis, Amanda R. Morales, John Raible

Department of Teaching, Learning, and Teacher Education: Faculty Publications

In this chapter, the authors outline the ongoing dialogues, thought processes, and pedagogical moves we make as two seasoned colleagues of color attempting to enhance the cultural competence of students through a critical multicultural education course offered at a public university-based teacher education program. We document how we address many enduring moral, ethical, and epistemological questions through our practice that are unique to educators of color working at predominantly white institutions (PWIs). We frame our work within the literature on diversity and social justice pedagogy and link our own work to the broader well-documented challenges faced by many educators of …

Board Of Regents Meeting Materials, February 18, 2021, Eastern Michigan University

Board of Regents Meeting Materials

No abstract provided.

Board Of Regents Meeting Materials, April 22, 2021, Eastern Michigan University

Board of Regents Meeting Materials

No abstract provided.

Board Of Regents Meeting Materials, October 14, 2021, Eastern Michigan University

Board of Regents Meeting Materials

No abstract provided.

The Foster Care System: Domestic Abuse, Guadalupe Hernandez Rodriguez

Nebraska College Preparatory Academy: Senior Capstone Projects

In the United States, children not only experience domestic abuse at home but can also be an issue while placed in the foster care system. In the foster care system, the abuse suffered by these individuals is increased due to home instability. Abuse can take place in many forms (physical, emotional, economical, and sexual) and can occur in many places. It can become a life-threatening crime or a crime that affects an individual’s day-to-day life. The youth and young adults who pass through this system are left with physical injuries and adverse childhood experiences (abuse, neglect, and household dysfunction). The …

Why We Create Enemies, Jerry Mejia

Nebraska College Preparatory Academy: Senior Capstone Projects

Our enemies are not always distinguishable by features such as a black trench coat or twirly mustache. However, humans still attempt to characterize their enemies into a stereotype. This is to create a sense of calm-you know who your enemy is. This research topic explored why society requires a scapegoat to feel better about its own shortcomings. Even if the worst happens, at least we will know who to blame. This has been human nature for thousands of years and will continue to do so.

Noise Exposure Potentiates Exocytosis From Cochlear Inner Hair Cells, Luis E Boero, Shelby Payne, Maria Eugenia Gómez-Casati, Mark A Rutherford, Juan D Goutman

Open Access Publications

Noise-induced hearing loss has gained relevance as one of the most common forms of hearing impairment. The anatomical correlates of hearing loss, principally cell damage and/or death, are relatively well-understood histologically. However, much less is known about the physiological aspects of damaged, surviving cells. Here we addressed the functional consequences of noise exposure on the capacity of inner hair cells (IHCs) to release synaptic vesicles at synapses with spiral ganglion neurons (SGNs). Mice of either sex at postnatal day (P) 15-16 were exposed to 1-12 kHz noise at 120 dB sound pressure level (SPL), for 1 h. Exocytosis was measured …

Cooperative Feeding In Common Dolphins As Suggested By Ontogenetic Patterns In Δ15N Bulk And Amino Acids, Rocio I. Ruiz-Cooley, Tim Gerrodette, Susan Chivers, Kerri Danil

United States Department of Commerce: Staff Publications

1. Understanding the effect of stage-specific traits on species feeding habits can reveal how natural selection shapes life strategies. Amino acid (AA) nitrogen stable isotopes (δ¹⁵N) provide multiple proxies of habitat baseline values and diet that can improve our understanding of species feeding strategies relative to their animal metabolism. We evaluated the effect of body length as a proxy for life stage and sex on the feeding habits of the common dolphin Delphinus delphis delphis using δ¹³C and δ¹⁵N in bulk tissue and AAs δ¹⁵N from skin samples collected for almost two …

Development And Validation Of A Deep Learning Model To Quantify Glomerulosclerosis In Kidney Biopsy Specimens, Jon N. Marsh, Ta-Chiang Liu, Parker C. Wilson, S. Joshua Swamidass, Joseph P. Gaut

Open Access Publications

Importance: A chronic shortage of donor kidneys is compounded by a high discard rate, and this rate is directly associated with biopsy specimen evaluation, which shows poor reproducibility among pathologists. A deep learning algorithm for measuring percent global glomerulosclerosis (an important predictor of outcome) on images of kidney biopsy specimens could enable pathologists to more reproducibly and accurately quantify percent global glomerulosclerosis, potentially saving organs that would have been discarded.

Objective: To compare the performances of pathologists with a deep learning model on quantification of percent global glomerulosclerosis in whole-slide images of donor kidney biopsy specimens, and to determine the …

Sex-Dimorphic Genetic Effects And Novel Loci For Fasting Glucose And Insulin Variability, Vasiliki Lagou, Ping An, Michael A. Province, Et Al.

Open Access Publications

No abstract provided.

Quantitative Evaluation Of Frequency Domain Measurements In High Density Diffuse Optical Tomography, Guy A. Perkins, Adam T. Eggebrecht, Hamid Dehghani

Open Access Publications

No abstract provided.

Dengue And The Lectin Pathway Of The Complement System, Romchat Kraivong, Nuntaya Punyadee, M Kathryn Liszewski, John P Atkinson, Panisadee Avirutnan

Open Access Publications

Dengue is a mosquito-borne viral disease causing significant health and economic burdens globally. The dengue virus (DENV) comprises four serotypes (DENV1-4). Usually, the primary infection is asymptomatic or causes mild dengue fever (DF), while secondary infections with a different serotype increase the risk of severe dengue disease (dengue hemorrhagic fever, DHF). Complement system activation induces inflammation and tissue injury, contributing to disease pathogenesis. However, in asymptomatic or primary infections, protective immunity largely results from the complement system's lectin pathway (LP), which is activated through foreign glycan recognition. Differences in N-glycans displayed on the DENV envelope membrane influence the lectin pattern …

Liver-Specific Deletion Of Mttp Versus Tm6sf2 Reveals Distinct Defects In Stepwise Vldl Assembly, Elizabeth P Newberry, Gregory W Strout, James A J Fitzpatrick, Nicholas O Davidson

Open Access Publications

No abstract provided.

Programmed Cell Death Recruits Macrophages Into The Developing Mouse Cochlea, Vikrant Borse, Tejbeer Kaur, Ashley Hinton, Kevin Ohlemiller, Mark E Warchol

Open Access Publications

Programmed cell death (PCD) plays a critical role in the development and maturation of the cochlea. Significant remodeling occurs among cells of the greater epithelial ridge (GER) of Kölliker's organ, leading to tissue regression and formation of the inner sulcus. In mice, this event normally occurs between postnatal days 5-15 (P5-15) and is regulated by thyroid hormone (T3). During this developmental time period, the cochlea also contains a large population of macrophages. Macrophages are frequently involved in the phagocytic clearance of dead cells, both during development and after injury, but the role of macrophages in the developing cochlea is unknown. …

Shifting Pathways Of Stimulant Use Among Individuals With Opioid Use Disorder: A Retrospective Analysis Of The Last Thirty Years, Matthew S Ellis, Zachary A Kasper, Stephen Scroggins

Open Access Publications

No abstract provided.

Follow The Metaplasia: Characteristics And Oncogenic Implications Of Metaplasia's Pattern Of Spread Throughout The Stomach, José B Sáenz

Open Access Publications

The human stomach functions as both a digestive and innate immune organ. Its main product, acid, rapidly breaks down ingested products and equally serves as a highly effective microbial filter. The gastric epithelium has evolved mechanisms to appropriately handle the myriad of injurious substances, both exogenous and endogenous, to maintain the epithelial barrier and restore homeostasis. The most significant chronic insult that the stomach must face is

Overlapping But Disparate Inflammatory And Immunosuppressive Responses To Sars-Cov-2 And Bacterial Sepsis: An Immunological Time Course Analysis, Tyler J Loftus, Ricardo Ungaro, Marvin Dirain, Philip A Efron, Monty B Mazer, Kenneth E Remy, Richard S Hotchkiss, Luer Zhong, Rhonda Bacher, Petr Starostik, Lyle L Moldawer, Scott C Brakenridge

Open Access Publications

Both severe SARS-CoV-2 infections and bacterial sepsis exhibit an immunological dyscrasia and propensity for secondary infections. The nature of the immunological dyscrasias for these differing etiologies and their time course remain unclear. In this study, thirty hospitalized patients with SARS-CoV-2 infection were compared with ten critically ill patients with bacterial sepsis over 21 days, as well as ten healthy control subjects. Blood was sampled between days 1 and 21 after admission for targeted plasma biomarker analysis, cellular phenotyping, and leukocyte functional analysis

Associations Between Education And Dementia In The Caribbean And The United States: An International Comparison, Jing Li, Jorge J Llibre-Guerra, Amal Harrati, Jordan Weiss, Ivonne Z Jiménez-Velázquez, Daisy Acosta, Juan De Jesús Llibre-Rodriguez, Mao-Mei Liu, William H Dow

Open Access Publications

Introduction: Despite high dementia prevalence in Hispanic populations globally, especially Caribbean Hispanics, no study has comparatively examined the association between education and dementia among Hispanics living in the Caribbean Islands and older adults in the United States.

Methods: We used data on 6107 respondents aged 65 and older in the baseline wave of the population-based and harmonized 10/66 survey from Cuba, the Dominican Republic, and Puerto Rico, collected between 2003 and 2008, and 11,032 respondents aged 65 and older from the U.S.-based Health and Retirement Study data in 2014, a total of 17,139 individuals. We estimated multivariable logistic regression models …

Harnessing The Potential Of Multiomics Studies For Precision Medicine In Infectious Disease, Rebecca A. Ward, Philip A. Mudd, Rachel M. Presti, Andrej Spec, Et Al

Open Access Publications

The field of infectious diseases currently takes a reactive approach and treats infections as they present in patients. Although certain populations are known to be at greater risk of developing infection (eg, immunocompromised), we lack a systems approach to define the true risk of future infection for a patient. Guided by impressive gains in "omics" technologies, future strategies to infectious diseases should take a precision approach to infection through identification of patients at intermediate and high-risk of infection and deploy targeted preventative measures (ie, prophylaxis). The advances of high-throughput immune profiling by multiomics approaches (ie, transcriptomics, epigenomics, metabolomics, proteomics) hold …

Evaluation Of Commercial Rapid Lateral Flow Tests, Alone Or In Combination, For Sars-Cov-2 Antibody Testing, Peter U Fischer, Kerstin Fischer, Kurt C Curtis, Yuefang Huang, Nicole Fetcho, Charles W Goss, Gary J Weil

Open Access Publications

Antibody tests can be tools for detecting current or past severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 [coronavirus disease 2019 (COVID-19)]) infections. Independent test evaluations are needed to document the performance with different sample sets. We evaluated six lateral flow assays (LFAs) and two laboratory-based tests (EUROIMMUN-SARS-CoV-2 ELISA and Abbott-Architect-SARS-CoV-2-IgG). We tested 210 plasma samples from 89 patients diagnosed with acute COVID-19. These samples were collected at different time points after the onset of symptoms. In addition, 80 convalescent plasma samples, and 168 pre-pandemic samples collected from adults in the United States and in Africa were tested. LFA performance varied …

Genome‑Wide Chromatin Accessibility Analyses Provide A Map For Enhancing Optic Nerve Regeneration, Wolfgang Pita-Thomas, Tassia Mangetti Gonçalves, Ajeet Kumar, Guoyan Zhao, Valeria Cavalli

Open Access Publications

No abstract provided.

Female And Male-Controlled Livestock Holdings Impact Pastoralist Food Security And Women’S Dietary Diversity, Henriette Gitungwa, Christopher Gustafson, E.Y. Jimenez, E. Wesley F. Peterson, M. Mwanzalila, Asha Makweta, E. Komba, R.R. Kazwala, J.A.K. Mazet, Elizabeth Vanwormer

School of Veterinary and Biomedical Sciences: Faculty Publications

Background: Food insecurity is a global problem that requires a One Health approach. As many households in low- and middle-income nations rely on crops and livestock that they produce to meet their household’s needs, food security and nutrition are closely linked to the health of animals and the environment. Resources controlled by women are more often allocated to uses that benefit the entire household, such as food, health, and educating children, than men’s resources. However, studies of gender control of resources among pastoralist societies are scant. We examined the effect of female and male control of livestock resources on food …

United States Army Report And Message Formats, United States Army

United States Army: Field Manuals

United States Army Report and Message Formats, United States Army Field Manual FM 6-99

Pesticide Occurrence And Persistence Entering Recreational Lakes In Watersheds Of Varying Land Uses, Jessica Satiroff, Tiffany Messer, Aaron R. Mittelstet, Daniel D. Snow

Nebraska Water Center: Faculty Publications

Currently little is known of newer pesticide classes and their occurrence and persistence in recreational lakes. Therefore, the objectives of this study were to (1) assess average pesticide concentrations and loadings entering recreational lakes in three mixed land use watersheds throughout the growing season, (2) evaluate pesticide persistence longitudinally within the lakes, and (3) perform an ecotoxicity assessment. Six sampling campaigns were conducted at three lakes from April through October 2018 to measure the occurrence and persistence during pre, middle, and post growing season. Polar organic chemical integrative samplers (POCIS) were placed in streams near lake inlets and monthly samples …

Occurrence Of Arsenite In Surface And Groundwater Associated With A Perennial Stream Located In Western Nebraska, Usa, Arindam Malakar, Rajesh Singh, Jeffrey Westrop, Karrie A. Weber, Christopher N. Elofson, Manish Kumar, Daniel D. Snow

Nebraska Water Center: Faculty Publications

Dissolved arsenic typically results from chemical weathering of arsenic rich sediments and is most often found in oxidized forms in surface water. The mobility of arsenic is controlled by its valence state and also by its association with iron oxides minerals, the forms of which are both influenced by abiotic and biotic processes in aqueous environment. In this study, speciation methods were used to measure and confirm the presence of reduced arsenic species in the surface water of Frenchman creek, a gaining stream that crosses the Colorado- Nebraska border. Selective extraction analysis of aquifer and stream bed sediments shows that …

Diversification Of Angiosperms During The Cretaceous Period, Sakia Fields

Department of Environmental Studies: Undergraduate Student Theses

The topic of the Angiosperms relatively sudden appearance and diversification is a topic that has puzzled plenty of biologists and is even referred to as an “abominable mystery” by Charles Darwin. Up to date, many hypotheses have been proposed using various forms of data to form them. The available knowledge used to evaluate this topic has changed over the years, which has created some theme shifts. Some of the best supported of these hypotheses are more recent, but this does not make older articles unworthy of being evaluated, as they still often have relevant information. In the past, their appearance …

How Is Remote Sensing Being Used To Prevent Wildfires Today?, Luke Lauby

Department of Environmental Studies: Undergraduate Student Theses

Wildfires frequencies and severities are on the rise. To properly combat and contain them, artificial intelligence should be utilized. An in-depth literature review was conducted in order to evaluate the current state of artificial intelligence specifically relating to wildfire prevention and suppression efforts. The findings in this research sheds further light on the helpful implications that these technologies (both satellites and UAVs) do, and can have on wildfire suppression. If further adopted in wildfire suppression efforts, artificial intelligence can play a more effective role. Through this, fires can become better prevented, more controllable, and better understood using modern technology.