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2021

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The Detection And Identification Of Blood On Interfering Substrates Using Raman Spectroscopy And Hamand For Forensic Purposes, Jalissa M. Thomas Jan 2021

The Detection And Identification Of Blood On Interfering Substrates Using Raman Spectroscopy And Hamand For Forensic Purposes, Jalissa M. Thomas

Legacy Theses & Dissertations (2009 - 2024)

Body fluids, such as blood and semen, can provide invaluable information to a criminal investigation. As such, it is imperative that body fluid evidence is properly detected and identified. Our laboratory has developed a methodology to universally detect and identify body fluids using Raman spectroscopy and chemometrics. This methodology was developed under ideal conditions, which are rare in the field. Body fluid evidence can be found on substrates that produce a large Raman signal that can hinder detection of body fluid traces, which produce a weak signal. This project proposes the use of a statistical program called HAMAND (Hypothetical Addition …

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Retrotransposon-Mediated Transduction Of An Environmental Cue To Regulate Centrosome Fate, Shawn Patrick Murphy Jan 2021

Retrotransposon-Mediated Transduction Of An Environmental Cue To Regulate Centrosome Fate, Shawn Patrick Murphy

Legacy Theses & Dissertations (2009 - 2024)

In 1969, the enrichment of mobile element repeat sequences led Britton and Davidson to propose the hypothesis that gene expression in higher eukaryotes is regulated through the exaptation of mobile elements. In this work, I have explored the hypothesis that mobile elements can also be harnessed by the host to regulate asymmetric cell division, thereby determining cell fate. Retrotransposons are ubiquitous eukaryotic mobile elements that transpose through an RNA intermediate. They are often active in cell types that divide asymmetrically to yield daughter cells with different fates, such as embryonic stem cells, germline stem cells, neuronal stem cells and the …

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The Phosphodiesterase, Rv0805, Is An Unheralded Component Of Tb Complex Mycobacterial Physiology In And Beyond Camp Homeostasis, James R. Mcdowell Jan 2021

The Phosphodiesterase, Rv0805, Is An Unheralded Component Of Tb Complex Mycobacterial Physiology In And Beyond Camp Homeostasis, James R. Mcdowell

Legacy Theses & Dissertations (2009 - 2024)

Phosphodiesterases (PDEs) are integral components of 3’,5’-cyclic adenosine monophosphate (cAMP) signaling pathways by degrading cAMP to modulate the concentration, duration, and localization of the cAMP signal which maintains the specificity of cAMP pathways. The human pathogen, Mycobacterium tuberculosis (Mtb) has a unique cAMP network architecture with at least 15 adenylyl cyclases (ACs) that generate cAMP, but only one characterized PDE, Rv0805, which is found exclusively in pathogenic mycobacteria. Rv0805 can influence Mtb cAMP levels but the absence of Rv0805 orthologs in non-pathogenic mycobacteria and apparent separation of Rv0805 from cAMP directed roles led to numerous questions surrounding PDE function in …

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Settler-Colonialism In Mexico : Mestizaje As A Project Of Elimination, Rosa Maria Navarro Jan 2021

Settler-Colonialism In Mexico : Mestizaje As A Project Of Elimination, Rosa Maria Navarro

Legacy Theses & Dissertations (2009 - 2024)

No abstract provided.

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Identification Of Ires Activity In Cellular Mrnas And Viral Rna Using A Circular Rna Construct, Priyanka Sehta Jan 2021

Identification Of Ires Activity In Cellular Mrnas And Viral Rna Using A Circular Rna Construct, Priyanka Sehta

Legacy Theses & Dissertations (2009 - 2024)

Translation initiation is a critical step in the process of protein synthesis. The canonical way of translation initiation involves ribosomes being recruited to the 7-methyl guanosine cap present at the 5’end of the untranslated region (5’ UTR) of the RNAs. However, viral RNAs and some cellular mRNAs lack this 5’ cap structure and thus deploy an alternate non-canonical translation initiation mechanism. In non-canonical translation initiation, ribosome recruitment is facilitated by the RNA secondary structures called Internal Ribosome Entry Site (IRES) present most often in the 5’ UTR. To measure IRES-mediated translation, the dual luciferase assay has been the gold standard. …

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Novel Functional Proteomics Techniques For Multiplex And Single Cell Cytokines Detection, Mohammed Abdullah Jan 2021

Novel Functional Proteomics Techniques For Multiplex And Single Cell Cytokines Detection, Mohammed Abdullah

Legacy Theses & Dissertations (2009 - 2024)

Since the early stages of biological research, the vital role of molecules in living creatures has been investigated and documented. According to Francis Watson's definition of the central dogma of biology, proteins are the final product of molecular biology and can't transfer information to other proteins like DNA or mRNA. Therefore, they are considered as the functional molecules of biology making them are more clinically relevant. However, the available techniques to study the protein characters, which coined laterally as proteomics science, are not well developed as genomics techniques did. Since the first human genome project is finished, the cost of …

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Role Of Rna Helicases In The Drosophila Germline, Patrick Blatt Jan 2021

Role Of Rna Helicases In The Drosophila Germline, Patrick Blatt

Legacy Theses & Dissertations (2009 - 2024)

Gametogenesis, the process of creating egg or sperm, is required for launching successive generations of sexually reproducing organisms. The developmental milestones that occur during gamete production have been studied for decades and are of critical interest to gain insight to conserved features of human fertility. Drosophila has been used for over a century as an efficient research model and remains pivotal in uncovering fundamental biological paradigms. During Drosophila egg production, or oogenesis, several developmental transitions must be traversed to ensure completion of oogenesis including: Germline Stem Cell (GSC) maintenance and differentiation, mitotic and meiotic cell divisions, and production of maternally …

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Methamphetamine-Induced Modulation Of Anxiety/Depressive-Like Behaviors And Hpa Axis Output : Contributing Factors Within Stress Associated Brain Regions, Jason Jacobskind Jan 2021

Methamphetamine-Induced Modulation Of Anxiety/Depressive-Like Behaviors And Hpa Axis Output : Contributing Factors Within Stress Associated Brain Regions, Jason Jacobskind

Legacy Theses & Dissertations (2009 - 2024)

Methamphetamine (MA) is a psychostimulant drug of addiction that induces a wide range ofeffects. Among its many side effects is the potentiation of cellular, physiological, and behavioral changes in the stress response system. Upon exposure, the hypothalamic-pituitary-adrenal (HPA) axis is initiated. This process entails many factors. Receiving input from other brain regions, the paraventricular nucleus (PVN) of the hypothalamus secretes corticotropin-releasing factor (CRF) and arginine vasopressin into the anterior pituitary gland. These together stimulate the synthesis and release of adrenocorticotropic hormone, which circulates via the blood stream to cause the release of glucocortoicoids, the stress hormone (CORT). Binding of glucocorticoids …

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Applied Methodologies Demonstrated Through Three Independent Studies For Assessing The Effects Of Socioeconomic, Environmental Chemical Exposure, And Therapeutic Factors On Oncological Diseases And Covid-19, Bayarmagnai Maggie Munkhjargal Jan 2021

Applied Methodologies Demonstrated Through Three Independent Studies For Assessing The Effects Of Socioeconomic, Environmental Chemical Exposure, And Therapeutic Factors On Oncological Diseases And Covid-19, Bayarmagnai Maggie Munkhjargal

Legacy Theses & Dissertations (2009 - 2024)

When trying to understand risk factors for a disease, even before we know the causal agents, it is necessary to create a surveillance data set that answers the questions of who, when, and where, and includes any potential covariates which may either promote or prevent the disease. There are a wide variety of surveillance data. For example, hospital discharge data, such as the New York Statewide Planning and Research Cooperative System (SPARCS) data, encompass all hospitalized cases in the state, while clinical datasets cover a specially constructed population in pursuit of research of a certain disease type. Analysis of surveillance …

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The Role Of Empathy In Moral Inquiry, William Gray Kidder Jan 2021

The Role Of Empathy In Moral Inquiry, William Gray Kidder

Legacy Theses & Dissertations (2009 - 2024)

In this dissertation, I defend the view that, despite empathy’s susceptibility to problematic biases, we can and should cultivate empathy to aid our understanding of our own values and the values of others. I argue that empathy allows us to critically examine and potentially revise our values by considering concrete moral problems and our own moral views from the perspective of another person. Appropriately calibrated empathy helps us achieve a critical distance from our own moral perspective and is thus tied to impartiality in moral inquiry. In defending this role for empathy in moral inquiry, I draw on empirical work …

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Missense Mutations In The Gamma Crystallins And Mechanisms Of Lens Opacity, Wenjuan Hou Jan 2021

Missense Mutations In The Gamma Crystallins And Mechanisms Of Lens Opacity, Wenjuan Hou

Legacy Theses & Dissertations (2009 - 2024)

Cataract, or clouding of the ocular lens, among the most common types of eye diseases, is the leading cause of blindness worldwide. With the opacity or clouding of the lens, light incident on the lens is scattered rather than being transmitted and is thus prevented from focusing on the retina. The lens becomes cataractous due to a large number of reasons, among which aging and genetic mutations are two of the most common factors. Clouding of the center of the lens or nuclear opacity, is the most frequently observed type of age-onset cataract, as well as inherited, congenital cataract [1, …

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Racism, Mental Health And The Role Of Racial Conflict For Multiracial People, Christina Martin Jan 2021

Racism, Mental Health And The Role Of Racial Conflict For Multiracial People, Christina Martin

Legacy Theses & Dissertations (2009 - 2024)

Objective: This study examined the moderating role of racial conflict among the relation between experiences of racial discrimination and mental health (psychological distress and psychological well-being) for the multiracial sub-group. Furthermore, this study was among the first to also explore how multifaceted identity choice/racial self-identification was associated with racism, racial tension, and mental health. Methods: Two hierarchical multiple regressions were conducted to assess the potential moderation effect of racial conflict on the relationships between racism and mental health for 242 multiracial adults using survey design and recruitment methods through Amazon’s Mechanical Turk and social media. Results: As predicted, experiences of …

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The Effect Of Mindfulness On Autonomic Nervous System Coordination In Individuals With Interparental Conflict Exposure, Rachel Clegg Jan 2021

The Effect Of Mindfulness On Autonomic Nervous System Coordination In Individuals With Interparental Conflict Exposure, Rachel Clegg

Legacy Theses & Dissertations (2009 - 2024)

Adverse childhood experiences, such as interparental conflict exposure, have long-term negative effects across various domains, including psychological and physiological health. Research reveals a link between interparental conflict and coordination between stress response systems, specifically sympathetic and parasympathetic nervous systems (SNS and PNS, respectively). Despite this knowledge, much less is known about potential protective factors or intervention strategies within this area. Mindfulness interventions have been found to be useful in the treatment of psychological and physical problems, including PTSD and stress-related diseases. The present study examined the effect of a mindfulness intervention on coordination between PNS, as measured by respiratory sinus …

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Mass Spectral And Chemometric Analysis For The Detection And Identification Of Forensically Relevant Materials, Meghan Grace Appley Jan 2021

Mass Spectral And Chemometric Analysis For The Detection And Identification Of Forensically Relevant Materials, Meghan Grace Appley

Legacy Theses & Dissertations (2009 - 2024)

Forensic science is the application of science to the law which in and of itself covers a substantial number of disciplines. Many of these involve the detection and identification of materials using analytical techniques. Traditional analysis methods include microscopy, spectroscopy and mass spectrometry. The materials encountered by forensic practitioners are ever evolving, resulting in the need to develop new methods to complement conventional techniques to enhance the evidentiary value of the samples. The research presented here shows that novel methods including direct analysis in real time–high-resolution mass spectrometry (DART-HRMS), thermal desorption coupled with gas chromatography-mass spectrometry (TD-GC-MS), solid-phase microextraction (SPME) …

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Rna Modifications As A Novel Mediator Of Viral Infection, Rachel Netzband Jan 2021

Rna Modifications As A Novel Mediator Of Viral Infection, Rachel Netzband

Legacy Theses & Dissertations (2009 - 2024)

Viral epitranscriptomics is a novel field of RNA biology. Chemical groups are appended to RNA nucleotides under different conditions in cells, and I examine these changes using a mass spectrometry-based approach. Various changes are found to occur in post-transcriptional modifications (PTMs) during viral infection. The field primarily studies a small number of PTMS, such as m6A, while I explore a variety of novel modifications and their impact on viral infection. Hepatitis C virus (HCV) infection induces a variety of modification changes, including the novel presence of dimethylcytosine (m5Cm/m44C). One Writer enzyme for this modification is determined to likely be METTL15, …

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Meeting Places : The Entanglements Of Poetry And Science In The Modern American Imagination, James H. Searle Jan 2021

Meeting Places : The Entanglements Of Poetry And Science In The Modern American Imagination, James H. Searle

Legacy Theses & Dissertations (2009 - 2024)

“Meeting Places: The Entanglements of Poetry and Science in the Modern American Imagination” explores how Ralph Waldo Emerson, W.E.B. Du Bois, William Carlos Williams, and Muriel Rukeyser responded to the rise of modern science and industrial technology by reflecting on the similarities and differences between the poetic and scientific imaginations. Across four chapters, I show how the growth of the natural and social sciences from the mid-nineteenth to mid-twentieth century spurred these writers to rethink the social and cultural functions of literature in a democratic society. Unlike many of their peers, these figures refused to treat science either as a …

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Impact Of Camouflaging On Females With Autism, Cortney Janicki-Menzie Jan 2021

Impact Of Camouflaging On Females With Autism, Cortney Janicki-Menzie

Legacy Theses & Dissertations (2009 - 2024)

Females with autism spectrum disorder are an underrepresented group in the autism literature that is in need of greater understanding. Growing evidence suggests that autistic females have a unique clinical presentation of symptoms and they are more frequently camouflaging their autism characteristics to fit in with peers. While support for social camouflaging theory builds, little attention has been paid to the effects of camouflaging on outcomes for females with autism. The current study proposes that females with autism will demonstrate greater use of camouflaging behaviors and that camouflaging behaviors will predict adverse outcomes for these women. Specific outcomes addressed in …

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Legacy And Emerging Per- And Polyfluoroalkyl Substances : Analysis, Environmental Distribution, And Bioconcentration, Richard Anthony Brase Jan 2021

Legacy And Emerging Per- And Polyfluoroalkyl Substances : Analysis, Environmental Distribution, And Bioconcentration, Richard Anthony Brase

Legacy Theses & Dissertations (2009 - 2024)

Per- and polyfluoroalkyl substances (PFAS) constitute a broad class of anthropogenic chemicals that have been used in numerous industrial and consumer-product applications since the late 1940s. The environmental persistence of these compounds in combination with their widespread commercial use have led PFAS to be recognized as contaminants of concern on the global scale. Despite regulatory efforts calling for the decreased use of certain perfluorocarboxylic and -sulfonic acids referred to as “legacy” PFAS, these compounds continue to be detected in both environmental and biological matrices. Moreover, manufacturers have begun to replace the legacy PFAS with emerging alternatives for which the regulations …

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Understanding Awol As A Crisis Response In Out-Of-Home Placement Settings, Stephen James Oby Jr Jan 2021

Understanding Awol As A Crisis Response In Out-Of-Home Placement Settings, Stephen James Oby Jr

Legacy Theses & Dissertations (2009 - 2024)

Youth elopement from out-of-home placement settings, an act colloquially referred to as AWOL, is a frequent and extremely risky outcome for youth and a key concern for child welfare entities. AWOL is hypothesized here as a maladaptive coping response to the experience of out-of-home placement as a crisis-inducing event. Conceiving of AWOL as a response to a crisis state redefines apparent risk factors as crisis origins and enables an understanding of which youth may experience a removal and out-of-home placement event as crisis inducing. Factors related to AWOL outcomes are embedded within an ecological systems framework and the interactions between …

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Application Of Direct Analysis In Real Time-High Resolution Mass Spectrometry To Genus- And Species-Level Differentiation And Identification Of Coral, Jessica Mary Hayes Jan 2021

Application Of Direct Analysis In Real Time-High Resolution Mass Spectrometry To Genus- And Species-Level Differentiation And Identification Of Coral, Jessica Mary Hayes

Legacy Theses & Dissertations (2009 - 2024)

Coral reefs are one of the most biologically diverse ecosystems, and the accurate identification of the species is essential for diversity assessment, species delimitation and conservation. Current species and genus determination approaches are time consuming, resource intensive and can be highly subjective. To explore the hypothesis that the small molecule profiles of coral are species and genus specific, and can be used as a rapid tool to catalogue, classify and identify coral genera and species, the small-molecule chemical fingerprints of coral belonging to the species Acanthastrea echinata, Catalaphyllia jardinei, Duncanopsammia axifuga, Echinopora lamellosa, Euphyllia divisa, Euphyllia paraancora, Euphyllia paradivisa, Galaxea …

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Study Of Primary Cilium Structure And Intraflagellar Transport, Shufeng Sun Jan 2021

Study Of Primary Cilium Structure And Intraflagellar Transport, Shufeng Sun

Legacy Theses & Dissertations (2009 - 2024)

Primary cilia are hair-like protrusions that stem from the basal bodies in the cytoplasm and extend into the extracellular space to sense signals. Intraflagellar transport (IFT) functions to transport cargo molecules into and out of the ciliary compartment to assemble, maintain, and disassemble the cilia. Accurate knowledge of the three-dimensional (3D) structure of primary cilia and precise details of the IFT profile is the foundation for understanding the sensory functions of primary cilia. This work covers three aspects of primary cilia. Firstly, we obtained and analyzed the overall 3D architecture of the complete primary cilia axoneme region using serial section …

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Behavioral, Endocrine, And Neural Responses To Stress In Postpartum And Nulliparous Rats : Potential Mechanisms Of Postpartum Stress Resilience, Joanna Medina Jan 2021

Behavioral, Endocrine, And Neural Responses To Stress In Postpartum And Nulliparous Rats : Potential Mechanisms Of Postpartum Stress Resilience, Joanna Medina

Legacy Theses & Dissertations (2009 - 2024)

Major depressive disorder is one of the most pervasive psychiatric illnesses in the United States. Women are at greater risk for developing depression, particularly during their childbearing years. Approximately 17% of new mothers develop postpartum depression within 4 weeks after parturition. The risk for postpartum depression is even greater in women who do not breastfeed or stop breastfeeding early. Major depressive disorder and postpartum depression share the same symptomology and common etiological bases. Dysregulated stress responses, dopamine activity, and neuroinflammation are recognized mechanisms for depression. The transition to motherhood encompasses physiological and behavioral adaptations in the brain essential for ensuring …

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Black Women Social Workers : A Qualitative Exploration Of Stress And Coping, Collina D. Cooke Jan 2021

Black Women Social Workers : A Qualitative Exploration Of Stress And Coping, Collina D. Cooke

Legacy Theses & Dissertations (2009 - 2024)

Black women social workers (BWSW) represent essential workforce members. They are burdened by overlapping expectations associated with their multiple marginalized and unique identities. Their definitions of stress and creation of strategies to deal with highly stressful situations have been absent from the research literature, leaving intervention strategies to support highly stressed BWSW unknown. This study was developed to explore stress perceptions and holistic manifestations of stress. A primary focus was to highlight the coping responses used by BWSW to decrease stress levels. In addition, the researcher sought to investigate various ways organizations have created stressful situations for BWSW and identify …

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Graduate Students' Intrinsic Motivation In Fully Online Courses, Ahmed Alahmari Jan 2021

Graduate Students' Intrinsic Motivation In Fully Online Courses, Ahmed Alahmari

Legacy Theses & Dissertations (2009 - 2024)

Motivation in general is one of the most important components of the process of learning and teaching in any educational environment, and it can explain the success or failure of student. In online learning, learners tend to study on their own and intrinsic motivation is particularly the main source that triggers and sustains learning process (Hartnett, 2016; Johnson et al., 2015; Shroff et al., 2007). Therefore, learners need high levels of intrinsic motivation to ensure success in their studies. Despite the emerging research regarding online learning, little attention has been given to graduate students’ intrinsic motivation in online courses. Therefore, …

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The Effects Of Cumulative Risk And Cross-Domain Risk On Preschooler's Executive Functioning Performance : The Buffering Role Of Parental Autonomy Support, Atara B. Siegel Jan 2021

The Effects Of Cumulative Risk And Cross-Domain Risk On Preschooler's Executive Functioning Performance : The Buffering Role Of Parental Autonomy Support, Atara B. Siegel

Legacy Theses & Dissertations (2009 - 2024)

There is robust evidence that early childhood adversity has wide ranging impacts on mental health, physical health and well-being in adulthood. Executive functioning (EF) deficits may partially mediate these effects, predisposing children to risky behavior and poor decision making. A growing body of research indicates that there is a link between early adversity and EF. However, more research is needed with younger children and with children at higher risk of multiple adversities. Measuring multiple adversities is complex, and researchers differ in their approaches to measuring cumulative adversity. Cumulative risk (CR) scores are an established method to capture important components of …

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Long Noncoding Rna Ak001796 As A Mediator Of Epithelial-To-Mesenchymal Transition In Metastatic Breast Cancer, Sumayya Adib Alchalabi Jan 2021

Long Noncoding Rna Ak001796 As A Mediator Of Epithelial-To-Mesenchymal Transition In Metastatic Breast Cancer, Sumayya Adib Alchalabi

Legacy Theses & Dissertations (2009 - 2024)

Long noncoding RNAs (lncRNAs) are emerging as key molecules regulating several cellular pathways and contributing to the development and progression of different diseases including cancer. The epithelial-to- mesenchymal transition (EMT), a molecular reprogramming process that plays a critical role in cancer metastasis, involves a complex interaction between protein coding and non-coding transcripts including lncRNAs. Understanding the biological significance of those lncRNAs of relatively unknown function, may help to uncover potential therapeutic targets for the aggressive subtypes of breast and other cancers. In this study, we examined the expression profiles of more than 17,000 lncRNAs in a large set of patients’ …

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Change And Continuity In Biology, Gunnar O'Neill Babcock Jan 2021

Change And Continuity In Biology, Gunnar O'Neill Babcock

Legacy Theses & Dissertations (2009 - 2024)

This dissertation considers various examples of change and continuity in biology. In particular, it focuses on the conceptual possibilities during the fission of microorganisms and genes when they multiply or replicate. Among the kinds of conceptual revision that are outlined in the first two chapters, the three chapter argues that certain concepts such as death, reproduction and organism have limited applicability in certain domains of biology. The fourth chapter investigates whether synthetic genomes should be considered parts of genetic lineages. It concludes that synthetic genomes are parts of the lineages upon which they were modeled. The final chapter aims to …

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Kinetic Characterization Of Two C-Family Polymerases From The Gram-Positive Bacterium Staphylococcus Aureus, Sean P. Fagan Jan 2021

Kinetic Characterization Of Two C-Family Polymerases From The Gram-Positive Bacterium Staphylococcus Aureus, Sean P. Fagan

Legacy Theses & Dissertations (2009 - 2024)

In this dissertation, I review the fundamental processes and mechanisms for bacterial DNA replication, especially the mechanisms employed by high-fidelity DNA polymerases to replicate the genome. Unlike the prototypical bacterial system from Escherichia coli which uses a single C-family polymerase, DNA polymerase IIIα (Pol IIIα), to replicate the genome, low-GC content Gram-positive bacteria utilize two essential C-family polymerases, PolC and DnaE. PolC and DnaE work cooperatively to replicate the genome, with DnaE initiating synthesis from RNA-primers and PolC performing the bulk synthesis. Although atomic structures of both PolC and Pol IIIα are available, detailed pre-steady state kinetic analysis of the …

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The Impact Of Problem Behaviors, Parenting And Availability Of Supports On Aspects Of Family Life In Children With Autism Spectrum Disorder, Celia Tam Jan 2021

The Impact Of Problem Behaviors, Parenting And Availability Of Supports On Aspects Of Family Life In Children With Autism Spectrum Disorder, Celia Tam

Legacy Theses & Dissertations (2009 - 2024)

It is well documented that children with autism spectrum disorder (ASD) tend to exhibit more problem behaviors compared to typical peers; moreover, parents of children with ASD are more likely to report experiencing greater parental and family stress. The current study set out to shed light on the ways and degree to which problem behaviors in children with ASD may impact multiple aspects of family life. The potential moderating role of family resources and perceived support, including emotional, physical, and disability-related support, along with certain parenting behaviors, was also explored. Participants included parents/caregivers of children diagnosed with ASD between the …

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Novel Sensing Concept For Organophosphate Monitoring, Cheyenne Bowman Jan 2021

Novel Sensing Concept For Organophosphate Monitoring, Cheyenne Bowman

Legacy Theses & Dissertations (2009 - 2024)

Organophosphates are a group of insecticides that are commonly used as chemical warfare agents (CWAs), since they can act as nerve agents by inhibiting acetylcholinesterase. Acetylcholinesterase is a vital enzyme of the central nervous system (CNS). This enzyme facilitates the breakdown of acetylthiocholine into thiocholine and acetate. The major goal of the research will be to provide a preliminary rapid, sensitive, and reliable method for sensing organophosphates. Current methods are enzyme inhibition-based – that is, a decrease in absorbance or signal yields a positive indicator for the presence of analyte. Herein, two different novel approaches to organophosphate sensing are described.The …

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