Digital Commons Network^™

The Effect Of Age On Neurological Inflammation To Acute Sleep Fragmentation In Mice, Molly Taylor

Mahurin Honors College Capstone Experience/Thesis Projects

Obstructive sleep apnea is identified by recurring events of airway collapse during sleep, intermittent hypoxia, and perturbations in sleep continuity, known as sleep fragmentation. There is evidence to suggest that elderly patients are more at risk of developing obstructive sleep apnea. The purpose of this study was to assess whether age affects neurological inflammatory responses to acute sleep fragmentation. This assessment was made by subjecting young (4-5 months old) and old (10-11 months old) male C57BL/6j mice to automated sleep fragmentation, as well as having mice in both age categories as a control with no sleep fragmentation, for twenty-four hours. …

Application Of Analogical Reasoning For Use In Visual Knowledge Extraction, Kara Lian Combs

Browse all Theses and Dissertations

There is a continual push to make Artificial Intelligence (AI) as human-like as possible; however, this is a difficult task because of its inability to learn beyond its current comprehension. Analogical reasoning (AR) has been proposed as one method to achieve this goal. Current literature lacks a technical comparison on psychologically-inspired and natural-language-processing-produced AR algorithms with consistent metrics on multiple-choice word-based analogy problems. Assessment is based on “correctness” and “goodness” metrics. There is not a one-size-fits-all algorithm for all textual problems. As contribution in visual AR, a convolutional neural network (CNN) is integrated with the AR vector space model, Global …

Volume Iv, Spring 2021, International Anchoritic Society

International Anchoritic Society Newsletter

No abstract provided.

Molecular Dynamics Of Bcs1l: A New Homology Model And The Structural Impact Of Pathogenic Mutations, Josh Deyoung, Sadie Heeringa, Rachael Baker, Amy Wilstermann

Summer Research

• Mutations to BCS1L can lead to one of three distinct rare diseases: Björnstad syndrome, BCS1L mitopathy, GRACILE syndrome
• These diseases cause a variety of symptoms in patients that range from mild (hearing loss and brittle hair) to severe and fatal (iron overload, failure to thrive, lactic acidosis, aminoaciduria, early death)

Upwelling Velocity And Ventilation In The Western South China Sea Deduced From Cfc-12 And Sf6 Observations, Weimin Wang, Peng Huang, Hengxiang Deng, Mian Chen, Minggang Cai, Zhiyou Jing, Shihao Luo, Xuehong Zheng, Chunhui Wang, Hongwei Ke

Journal of Marine Research

This study presents observations of the transient tracers CFC-12 and SF₆ in the western South China Sea during the fall of 2015. A CFC-12 maximum was discovered in the western South China Sea at the subsurface layer (150–200 m), which could be traced back to the North Pacific Tropical Water. The transit time distribution approach was used to estimate the ventilation time in this area. The constrained Δ /Γ ratio of 0.5 was obtained using CFC-12/SF₆ tracer pair. This ratio is lower than the empirical unit ratio of one as used for previous estimates. Waters in the northern …

Editor's Commentary: A Bathythermograph, Kenneth H. Brink

Journal of Marine Research

In this classic, Athelstan Spilhaus reports on his progress on a prototype of the mechanical bathythermograph, a project that C.-G. Rossby encouraged him to pursue. Although now most often seen in museums or on movie sets (they look a bit like rockets), bathythermographs were extremely influential from the later 1930s into the 1950s. These remarkable, durable instruments allowed continuous traces of temperature versus depth (previously measured as bottle temperatures at typically 50-m separations), and so opened up an entirely new vision of what ocean thermal structure actually looks like. Spilhaus further provides some actual data...

Classic Article: On The Process Of Upwelling, H. U. Sverdrup

Journal of Marine Research

The phenomenon of upwelling which is present along many coasts has been discussed from various points of view. A general explanation of the phenomenon has been given by application of Ekman’s theory of wind driven currents (Thorade 1909; McEwen 1912), and emphasis has been put on the velocity of the vertical motion (McEwen 1934) or on the depth from which water is brought to the surface (Sverdrup 1930; Gunther 1936). Defant (1936) has discussed the horizontal and vertical motion and the distribution of density within the region of upwelling off the coast of southwest Africa, but his analysis is based …

Viropana (Vna) 2, Abijeet Singh Mehta, Panagiotis A. Tsonis, Amit Singh

Components of a Regeneration Toolkit: Notophthalmus viridescens

Viropana (vna) 2

• ID – vna 2
• Details – Gene from a novel protein family belonging to the regeneration tool kit of Notophthalmus viridescens
• Base pairs – 396

Research And Creative Activity, July 1, 2020-June 30, 2021: Major Sponsored Programs And Faculty Accomplishments In Research And Creative Activity, University Of Nebraska-Lincoln, Office Of Research And Economic Development, University Of Nebraska-Lincoln

Office of Research and Economic Development: Publications

Foreword by Bob Wilhelm, Vice Chancellor for Research and Economic Development, University of Nebraska-Lincoln:

This booklet highlights successes in research, scholarship and creative activity by University of Nebraska–Lincoln faculty during the fiscal year running July 1, 2020, to June 30, 2021.

It lists investigators, project titles and funding sources on major grants and sponsored awards received during the year; fellowships and other recognitions and honors bestowed on our faculty; books and chapters published by faculty; performances, exhibitions and other examples of creative activity; patents and licensing agreements issued; National Science Foundation I-CORPS teams; and peer-reviewed journal articles and conference presentations. …

M.S. Environmental Biology Capstone Project, Shanelle Thevarajah

Regis University Student Publications (comprehensive collection)

Chapter 1: Coexistence begins with respect: human impacts on brown bears (Ursus arctos)

Chapter 2: Grizzly bear foraging patterns in relation to human disturbances in Sweden

Chapter 3: Activity budgets and social relationships of bull Asian elephants (Elephas maximus) at Denver Zoo

Chapter 4: Loris trade not so slow: conservation and welfare of slow lorises

Why Homogeneous Membranes Lead To Optimal Water Desalination: A Possible Explanation, Julio Urenda, Martine Ceberio, Olga Kosheleva, Vladik Kreinovich

Departmental Technical Reports (CS)

A recent experiment has shown that out of all possible biological membranes, homogeneous ones proved the most efficient water desalination. In this paper, we show that natural symmetry ideas lead to a theoretical explanation for this empirical fact.

Race-Insurance Disparities In Prostate Patients’ Magnetic Resonance Imaging Biopsies And Their Subsequent Cancer Care; A New York State Cohort Study [Protocol], Mansi Chandra, Seth Greenspan, Xiaoning Li, Jie Yang, Annie Laurie Shroyer, John P. Fitzgerald

Department of Urology Faculty Publications

No abstract provided.

Concurrent Validity And Reliability Of The Load-Velocity Relationship To Predict The One-Repetition Maximum During Three Weightlifting Derivatives, Ricardo Berton, Marcos Soriano, Demostenys David Da Silva, Marcel Lopes Dos Santos, Gustavo Teixeira, Fernando Reiser, Valmor Tricoli

Faculty Publications - Kinesiology and Recreation

The study investigated the concurrent validity and reliability of the load-velocity relationship to predict the one-repetition maximum (1RM) of the power clean from the knee (PCK), high pull from the knee (HPK), and mid-thigh clean pull (MTCP). For each exercise, 12 participants performed two 1RM sessions tests and two sessions to measure the barbell’s load-velocity relationship at 30, 45, 60, 75, and 90% of 1RM. The velocity recorded at each load was used to establish the linear regression equation and, consequently, to predict 1RM value. A low validity between the 1RM direct test and predicted 1RM was observed for PCK …

2021-2022 - Etsu General Academic Analysis Tables (October), Budget And Financial Planning, East Tennessee State University

ETSU General Academic Operating Budgets and Analysis

No abstract provided.

Berryman, Matilene Spencer, Msrc Staff

Manuscript Division Finding Aids

The papers of Attorney Matilene Spencer Berryman (1926-2003), reflect a legacy of outstanding achievements and accomplishments related to her work as an oceanographer, college professor and administrator in marine and environmental science as well as an attorney. The collection spans from 1964 to 2001, and measure twenty two cubic feet. The bulk of the papers covers the period from 1973-2000. In 2010, Moorland Spingarn Research Center acquired the collection from the estate of the late Dr. Sherrill Berryman Johnson, Berryman’s eldest daughter’s. Berryman's papers primarily consist of documents relating to her educational career inclusive of materials from her graduate studies …

Continuous Improvement Of Instructional Materials, David Wiley, Ross Strader, Robert Bodily

Entrepreneurship Faculty Research

From time-to-time new technologies provide us with a qualitatively different ability to engage in previously possible activities. For example, 20 years ago it was already possible to publish an essay online. You simply used the command line program Telnet to login to a remote server, navigated into the directory from which your webserver made html files available to the public, launched the pico editor from the command line, wrote your essay, and manually added all the necessary html tags. Today, open-source blogging software like WordPress makes publishing an essay online as easy as using a word processor. Yes, it was …

Ionizable Lipid Nanoparticles For In Utero Mrna Delivery., Rachel S. Riley, Meghana V Kashyap, Margaret M Billingsley, Brandon White, Mohamad-Gabriel Alameh, Sourav K Bose, Philip W Zoltick, Hiaying Li, Rui Zhang, Andrew Y Cheng, Drew Weissman, William H Peranteau, Michael J Mitchell

Henry M. Rowan College of Engineering Departmental Research

Clinical advances enable the prenatal diagnosis of genetic diseases that are candidates for gene and enzyme therapies such as messenger RNA (mRNA)-mediated protein replacement. Prenatal mRNA therapies can treat disease before the onset of irreversible pathology with high therapeutic efficacy and safety due to the small fetal size, immature immune system, and abundance of progenitor cells. However, the development of nonviral platforms for prenatal delivery is nascent. We developed a library of ionizable lipid nanoparticles (LNPs) for in utero mRNA delivery to mouse fetuses. We screened LNPs for luciferase mRNA delivery and identified formulations that accumulate within fetal livers, lungs, …

Understanding Changes In Marine Communities Through A Discretized, Size-Structured Matrix Model, Courtney Swanson

Senior Seminars and Capstones

We study a discretized, size-structured matrix model which calculates population in a marine community over time. A portion of this model is a discretized version of the McKendrick-von Foerster equation, so we spend some time studying the process of discretizing that equation. We implement a mini model containing 10 size categories instead of the original 50, and we looked at how the marine community behaves over 40 years. We discuss some of the challenges when implementing this model.

The Impact Of Early Deprivation On A Child's Cognitive And Social/Emotional Development, Hannah Grace Miller

All Electronic Theses and Dissertations

This literature review seeks to answer the question of: “What effect does early deprivation have on the cognitive and social/emotional development of a child?” Education is constantly changing, and one part that has dramatically shaped and shifted since its inception in 1975 is the area of special education. Within special education is a vast spectrum of student needs and differences. In order to be effective, teachers need to know their students’ strengths, areas of need, and anything else that plays a role in how they learn. This paper seeks to bring more clarity to how trauma, specifically the trauma of …

Ua68/14 Newsletter, Wku Folk Studies & Anthropology

WKU Administration Documents

Newsletter created by and about WKU Folk Studies & Anthropology.

• Applegate, Darlene. From the Department Head & Anthropology Program Director
• Ferrell, Ann. From the Folk Studies Program Director
• Student Profiles - Georgia Dassler, Camille Acosta
• Student Profiles - Azadeh Najafian, Corbin Pike
• Student Profiles - James Skaggs, Jordan Mansfield
• Student Projects
• This Year's Graduates
• Department Events & Activities
• Faculty/Staff News - Tim Frandy, Darlene Applegate, Ann Ferrell
• Faculty/Staff News - Gwynn Henderson, Erika Brady, Jean-Luc Houle, Kate Hudepohl, David Pollack, Justin Carlson
• Kentucky Folklife Program
• Kentucky Archaeological Survey
• Alumni Updates

2020-2021 Undergraduate Catalog, Sacred Heart University

Graduate & Undergraduate Catalogs

No abstract provided.

William H. Hannon Library Year In Review 2020 – 2021, William H. Hannon Library

William H. Hannon Year-in-Reviews

No abstract provided.

The Role Of Vps54 In Drosophila Melanogaster Neuronal Development And Age Progressive Neurodegeneration, Emily Wilkinson

Electronic Theses and Dissertations

Vps54 is a subunit of the Golgi-associated retrograde protein (GARP) complex, which is involved in tethering endosome-derived vesicles to the trans-Golgi network (TGN). The “wobbler” mouse is the phenotypic result of a destabilizing point mutation in Vps54. This mutation causes neurodegeneration and is subsequently used as a model for human motor neuron disease. Presently, it is unclear how disruption of GARP complex function leads to motor neuron degeneration. To better understand the role of Vps54 in motor neuron development, function, and age-related neurodegeneration, we disrupted expression of the Vps54 ortholog in Drosophila and examined the impact on larval neuromuscular junction …

Compressible Hydrodynamics Of Few Body Optical Vortices, Jasmine M. Andersen

Electronic Theses and Dissertations

The ubiquity of vortices nearly rivals that of the innumerable fluids and spaces in which they live. Not only do they exist in systems such as superfluids, superconductors, optical fields, or cold atomic gases, for example, but they also exist in our atmospheres, oceans, and even in our veins. This makes understanding and accurately predicting the dynamics of vortices in various systems a relevant and meaningful endeavor.

From a typical hydrodynamic perspective, vortices move within a given fluid because of the background fluid density and phase gradients at the vortex location. However, we find that these gradients alone are insufficient …

A. B.A.L.A.N.C.E.: A Well-Being Research Study, Reggie Gwinn

Electronic Theses and Dissertations

The purpose of this study has been to investigate the impact of a well-being intervention, using a well-being curriculum, known as A. B.A.L.A.N.C.E.. The method of educational criticism and connoisseurship was used as the qualitative method. Educational criticism is rooted in the process of expressing the specific qualities of one’s observations, while educational connoisseurship is rooted in the process of appreciation. The intervention will be conducted by an interventionist, myself, who gave the 10-lesson intervention to six 6th grade (11 – 12 years old) participants over a two-week period. This was orchestrated over a technological platform known as Zoom. It …

Understanding Challenges To Well-Being Among Latina Farmworkers In Rural Idaho Using In An Interdisciplinary, Mixed-Methods Approach, Cynthia L. Curl, Lisa Meierotto, Rebecca L. Som Castellano

Public and Population Health Faculty Publications and Presentations

The aim of this study was to identify social, cultural and workplace-related risk factors affecting well-being among Latina farmworkers in rural Idaho. We recruited 70 Latina farmworkers from southwestern Idaho in 2019. We employed an inter-disciplinary, mixed-methods approach—including surveys, focus groups, interviews, and pesticide biomonitoring—to characterize multiple domains that influence well-being, including food security and access, housing conditions, social supports, access to medical care, and workplace safety. Six major themes emerged as primary challenges to Latina farmworkers’ well-being. In the public sphere, study participants identified these challenges as long working hours, concerns regarding pesticide exposure, and lack of enforcement of …

Bryophyte Ecology, Janice M. Glime

Open Access Books

Bryophyte Ecology is an ebook comprised of 5 volumes written by Janice Glime, Professor Emerita of Biological Sciences at Michigan Technological University. Chapter coauthors include Irene Bisang, S. Robbert Gradstein, J. Lissner, W. J. Boelema, and D. H. Wagner.

This book is written in the hope that it is useful to a broad audience, from children to seasoned professionals. Its citations help the scientist find further information. The images help the beginner to understand. Its aim is to broaden the group of people who appreciate and understand the roles that bryophytes play in our world.

For videos that accompany the …

The Impact Emotions Have On Recall, Sadie-Marie Wright

Undergraduate Research Posters 2021

The relationship of how emotions impact the way a person remembers events has helped improve fields outside of psychology, such as criminal justice and biology. Most studies that explore emotions and recall have had inconclusive results due to factors such as participants being tasked with free recall in response to stimuli such as the study done by Gorlin et al. (2018). With that knowledge, the current study focused on a task of recall from a short list of words along with a direct stimulus in the form of an emotional or non-emotional passage with hopes that it would affect the …

Resting-State Cerebral Perfusion Patterns: An Exploratory Factor Analysis Of Single-Photon Emission Computed Tomography Clinical Data, Scott Harcourt

Theses and Dissertations

Resting-state (RS) networks (neural regions demonstrating a temporal correlation when a person is not engaged in deliberate activity) are a new topic in neuroscience and neuropsychology, not gaining significant traction in the literature until 2005. Few studies have used single-photon emission computed tomography (SPECT) regional cerebral blood flow (rCBF) to analyze RS. The omission is critical because SPECT RS networks have a different structure and statistical representation than functional magnetic resonance imaging (fMRI) RS networks. Moreover, recent fMRI research has explored RS differences in persons with psychopathology but have not studied brain-behavior assessment with the potential of application of neuropsychological …

The Structure Of The Cysteine-Rich Region From Human Histone-Lysine N-Methyltransferase Ehmt2 (G9a), Keshia M. Kerchner, Tung-Chung Mou, Yizhi Sun, Domniţa-Valeria Rusnac, Stephen R. Sprang, Klára Briknarová

Biological Sciences Faculty Publications

Euchromatic histone-lysine N-methyltransferase 1 (EHMT1; G9a-like protein; GLP) and euchromatic histone-lysine N-methyltransferase 2 (EHMT2; G9a) are protein lysine methyltransferases that regulate gene expression and are essential for development and the ability of organisms to change and adapt. In addition to ankyrin repeats and the catalytic SET domain, the EHMT proteins contain a unique cysteine-rich region (CRR) that mediates protein-protein interactions and recruitment of the methyltransferases to specific sites in chromatin. We have determined the structure of the CRR from human EHMT2 by X-ray crystallography and show that the CRR adopts an unusual compact fold with four bound zinc atoms. The …