Digital Commons Network^™

Research On Cgf-Oriented Virtual Human Perceptual Attention Model, Weilong Yang, Xu Kai, Xie Xu, Sun Lin

Journal of System Simulation

Abstract: Perception model is an important research field of CGF behavior modeling. As the input of the reasoning module, the information obtained from the perception model has an important influence on the fidelity of the simulation. The CGF perception model is researched, and the attention mechanism, effective time of attention model is analyzed, compared with the traditional model of perception. By modeling the knowledge base and information feedback, a virtual human perception framework based on attention mechanism is proposed, and the experiment is carried out in the simulation environment.

Overview Of Cgf-Oriented Cognitive Architecture, Xu Kai, Junjie Zeng, Weilong Yang, Qin Long, Quanjun Yin

Journal of System Simulation

Abstract: In order to further formalize and boost standardized behavioral model development of Computer Generated Forces (CGF), the CGF-oriented cognitive architecture is reviewed and the implementation details of one of the CGF cognitive behaviors, i.e. plan recognition, upon standard cognitive architecture are designed. The results show that the well-designed architecture has a strong support for complex behavior modeling. Four specific suggestions, including requirement analysis, design implementation, theoretical principle and cooperation mechanism, for architecture design and complex behavior modeling are provided.

Mutational And Biophysical Robustness In A Prestabilized Monobody, Peter G. Chandler, Li Lynn Tan, Benjamin T. Porebski, James S. Green, Blake T. Riley, Sebastian S. Broendum, David E. Hoke, Robert J. Falconer, Trent P. Munro, Malcolm Buckle, Colin J. Jackson, Ashley M. Buckle

Advanced Science Research Center

The fibronectin type III (FN3) monobody domain is a promising non-antibody scaffold, which features a less complex architecture than an antibody while maintaining analogous binding loops. We previously developed FN3Con, a hyperstable monobody derivative with diagnostic and therapeutic potential. Prestabilization of the scaffold mitigates the stability–function trade-off commonly associated with evolving a protein domain toward biological activity. Here, we aimed to examine if the FN3Con monobody could take on antibody-like binding to therapeutic targets, while retaining its extreme stability. We targeted the first of the Adnectin derivative of monobodies to reach clinical trials, which was engineered by directed evolution for …

Ecological Restoration And Countmeasures Against Desertification Crisis In Aral Sea Region., Mingzhu He, Xin Gao, Zhenyong Zhao, Haotian Yang, Lei Huang, Xinrong Li, Jiaqiang Lei

Bulletin of Chinese Academy of Sciences (Chinese Version)

Land degradation and desertification are the serious ecological problems and challenges to achieve global sustainable development goals. The Chinese government proposes to integrate the construction of the Silk Road Economic Belt with the environmental improvement of the Central Asia, to build an intimate community of shared destiny between China and the Central Asia countries, and to promote the green and sustainable development of the Silk Road Economic Belt. However, the ecological crisis in the Aral Sea causes a significant shrinking in water body, loss of biodiversity, salinization, desertification, and salt dust storm, which have become major environmental problems encountered in …

Developing Ocean Negative Carbon Emission Technology To Support National Carbon Neutralization., Nianzhi Jiao

Bulletin of Chinese Academy of Sciences (Chinese Version)

Carbon neutrality is the right means to cope with global warming. The basic approaches to achieve carbon neutralization include reducing CO2 emissions to the atmosphere and increasing carbon sinks or negative emissions (absorption of atmospheric CO2). As a developing country and a big emitter, China should try its best to increase carbon sinks while reducing emissions as much as possible. The ocean is the largest active carbon pool on Earth, with great potentials for carbon negative emission. We have established marine carbon sequestration theory, which has laid solid foundation for negative emission and set up the linkage between science and …

Factors Affecting Outbreaks And Prevention And Control Strategies Of Wildlife Infectious Diseases, Zhibin Zhang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Recently, wildlife infectious diseases have become a more and more serious problem in the world which imposes a big threat to bio-safety and eco-safety of worldwide. Accelerated climate change and human activities are key driving forces in causing more frequent occurrences of wildlife infectious diseases. Climate change could create favorable conditions for large-scale outbreak or invasion of wildlife infectious diseases by altering range shift or habitat of wildlife infectious diseases or their host/vectors. Human disturbance increases interspecific transmission of pathogens across people, wild and domestic animals, as well as their spread velocity facilitated by the modern transportation systems, and then …

Regionalization Of Ecological Risk Of China-Mongolia-Russia Economic Corridor Transportation And Pipeline Construction And Policy Suggestions, Suocheng Dong, Yijia Li, Fujia Li, Jingwen Li, Yu Li, Zehong Li, Hao Cheng, Guoyu Li, Shengyu Li

Bulletin of Chinese Academy of Sciences (Chinese Version)

The cross-border railways and oil and gas pipelines along the China-Mongolia-Russia Economic Corridor are key hubs and channels supporting the regional cooperation and development. It is very important to complete scientific regionalization of ecological risk of China-Mongolia-Russia Economic Corridor and put forward suggestions to guarantee smooth construction and safe cross-border traffic project. By establishing ecological risk evaluation model, we quantitatively analyzed the ecological risk of China-MongoliaRussia Economic Corridor, and regionalized high, middle, and low risk. We put forward the ecological risk prevention and control countermeasures for China-Mongolia-Russia Economic Corridor. It shows that the ecological risk areas are distributed along the …

Visions And Scenarios Of People And Science And Technology Development To 2030, Fuhai Leng, Hong Li, Jianfang Wang, Zhongyang Xi, Qiuju Zhang, Xiaoyi Chen, Chunlei Ge, Dong Liu, Jing Ye, Xiaoqi Jia, Chao Li, Chao Ai, Huajun Cao

Bulletin of Chinese Academy of Sciences (Chinese Version)

In the next 10 to 15 years, scientific and technological progress will change the industrial structure and global economic growth, and will profoundly change people’s needs for food, clothing, housing, transportation and their forms of the needs to meet. Based on the foresight analysis data of economic, social, and technological development from major countries and international organizations or big enterprises, with the method of information and knowledge element analysis, this study describes humanbased vision from the following five aspects, life, work, health, information, and safety. For each aspect, we put forward some social development trends, visions, specific scenarios, and key …

Wuhan National Geodetic Observatory

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

High-Precision Superconducting Gravimetric Observations And Investigations Provide National Surveying And Mapping And Earth’S Dynamics With Theoretical Fundamentals, Heping Sun, Jiangcun Zhou, Jianqiao Xu, Xiaodong Chen, Xiang'e Lei, Xiaoming Cui, Xiaowei Niu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Since 1985, about 35-year high-precision gravity data have been being well accumulated and worldwide cooperation was effectively carried out. The unique international tidal gravity reference in Asia was established. The background noise model for low frequency in Chinese continent was constructed. A global experimental model and an accurate correction model in Chinese continent for gravity tides of the Earth were both constructed. The theoretical simulation of the effect of surface mass loading on gravity was improved. The signals related to the nearly diurnal resonance, Earth’s free oscillation and translational wobble of the Earth’s inner core were detected to investigate the …

Founders' Day Convocation (2021 Program And Video), Illinois Wesleyan University

Founders’ Day

No abstract provided.

Navigating The Blue Economy, Edward Canuel

William & Mary Environmental Law and Policy Review

The time has come, the Walrus said,

To talk of many things:

Of shoes—and ships—and sealing-wax—

Of cabbages—and kings—

And why the sea is boiling hot—

And whether pigs have wings.

And like the conversation of the Walrus and Carpenter walking along the “wet as wet could be” sea, the blue economy offers us the opportunity to talk of many things. Part I of this Article analyzes what the blue economy is and its relevance. Governance mechanisms, including ecosystem-based management and marine spatial planning are introduced and reviewed. The section discusses the benefits associated with such mechanisms, including streamlined decision-making, …

Molecular Characterization Of Tick Galectin In Context Of Α-Gal Syndrome, Sumar Beauti

Mississippi Undergraduate Honors Conference

α-Gal Syndrome (AGS) is a tick-borne delayed hypersensitivity reaction that occurs 3-6 hours after red meat consumption. It is induced by oligosaccharide galactose-α-1,3-galactose (α-gal) found in the Lone Star tick, Amblyomma americanum, and all mammalian-derived foods. α-gal specific IgE (sIgE) antibodies are produced after α-gal transmission from the tick bite and activates after subsequent red meat consumption. Previously, an immune-affinity approach utilized α-Gal antibody to isolate and identify covalently linked tick saliva antigens to α-gal followed by Liquid Chromatography-tandem Mass Spectrometry (LS-MS/MS) analysis. The identified antigen included tick salivary Galectin, a carbohydrate-binding protein involved in many physiological functions such as …

Transitioning To College: Experiences Of Successful First-Generation College Students, Jonathan R. Ricks, Jeffrey M. Warren

Journal of Educational Research and Practice

This qualitative study explored the high school to college transition experiences of ten successful first-generation college students (FGCS). Participants were college seniors at an historically black university in the United States. A generic qualitative research design was used, including in-depth, semi-structured interviews to collect and analyze data. Participants reported that the transition experience led to confusion with academic and financial procedures, various emotions including anxiety and fear, the realization that they had deficits in academic skills, and the receipt of support from family members and others. Cultural and social capital appeared to play key roles in their success. Student affairs …

The Fierce Green Fire: Vol. 11 Issue 3, Wofford College. Department Of Environmental Studies

The Fierce Green Fire

No abstract provided.

Recent Advances In The Application Of Crispr/Cas9 Gene Editing System In Poultry Species, Collins N. Khwatenge, Samuel N. Nahashon

Agricultural and Environmental Sciences Faculty Research

CRISPR/Cas9 system genome editing is revolutionizing genetics research in a wide spectrum of animal models in the genetic era. Among these animals, is the poultry species. CRISPR technology is the newest and most advanced gene-editing tool that allows researchers to modify and alter gene functions for transcriptional regulation, gene targeting, epigenetic modification, gene therapy, and drug delivery in the animal genome. The applicability of the CRISPR/Cas9 system in gene editing and modification of genomes in the avian species is still emerging. Up to date, substantial progress in using CRISPR/Cas9 technology has been made in only two poultry species (chicken and …

Identifying Receptors For Neuropeptides And Peptide Hormones: Challenges And Recent Progress, Md Shadman Ridwan Abid, Somayeh Mousavi, James W. Checco

Department of Chemistry: Faculty Publications

Intercellular signaling events mediated by neuropeptides and peptide hormones represent important targets for both basic science and drug discovery. For many bioactive peptides, the protein receptors that transmit information across the receiving cell membrane are not known, severely limiting these signaling pathways as potential therapeutic targets. Identifying the receptor(s) for a given peptide of interest is complicated by several factors. Most notably, cell-cell signaling peptides are generated through dynamic biosynthetic pathways, can act on many different families of receptor proteins, and can participate in complex ligand-receptor interactions that extend beyond a simple one-to-one archetype. Here, we discuss recent methodological advances …

Ex Uno, Plures-From One Tissue To Many Cells: A Review Of Single-Cell Transcriptomics In Cardiovascular Biology., Elvira Forte, Michael A Mclellan, Daniel A Skelly, Nadia Rosenthal

Faculty Research 2021

Recent technological advances have revolutionized the study of tissue biology and garnered a greater appreciation for tissue complexity. In order to understand cardiac development, heart tissue homeostasis, and the effects of stress and injury on the cardiovascular system, it is essential to characterize the heart at high cellular resolution. Single-cell profiling provides a more precise definition of tissue composition, cell differentiation trajectories, and intercellular communication, compared to classical bulk approaches. Here, we aim to review how recent single-cell multi-omic studies have changed our understanding of cell dynamics during cardiac development, and in the healthy and diseased adult myocardium.

Crossroads Camps Return To Gardner-Webb For Sold-Out Week In July, Office Of University Communications

Gardner-Webb NewsCenter Archive

Gardner-Webb University alumnus Clayton King is bringing a week of Crossroads Camps back to the GWU campus this summer—and it’s already sold out. King founded the non-profit Christian ministry in 1995 when he was a senior at Gardner-Webb.

In Vitro Analysis Of The Antioxidant And Antiviral Activity Of Embelin Against Herpes Simplex Virus-1, Tony Elias, Lee H. Lee, Miriam Rossi, Francesco Caruso, Sandra D. Adams

Department of Biology Faculty Scholarship and Creative Works

Herpes simplex virus-1 (HSV-1) causes a wide range of infections from mild to life-threatening in the human population. There are effective treatments for HSV-1 infections that are limited due HSV-1 latency and development of resistance to current therapeutics. The goal of this study was to investigate the antioxidant and antiviral effects of embelin on HSV-1 in cultured Vero cells. Oxidative stress was verified by an extensive production of a reactive oxygen species (ROS) H2O2. Vero cells were infected with a recombinant strain of HSV-1 and antiviral assays, time course attachment, penetration, and post penetration assays, confocal microscopy, qPCR, and antioxidant …

Zoonotic Diseases: New Directions In Human–Animal Pathology, Robin Bendrey, Debra Martin

Anthropology Faculty Research

Zoonotic diseases—human diseases of animal origin—represent one of the world's greatest health challenges, both today and in the past. Since the Neolithic, zoonotic diseases have been one of the major factors shaping and influencing human adaptation. Archaeology is ideally situated to provide the long view on human–animal–pathogen relationships through combining cultural, environmental and biological datasets, yet long-term studies of linked human and animal records have often been overlooked and undertheorized. The seven papers in this special issue “Zoonotic diseases: New directions in human–animal pathology” cover a range of diseases caused by bacterial, viral, and parasitic pathogens, from case studies drawn …

Protease Oma1 Modulates Mitochondrial Bioenergetics And Ultrastructure Through Dynamic Association With Micos Complex, Martonio Ponte Viana, Roman M. Levytskyy, Ruchika Anand, Andreas S. Reichert, Oleh Khalimonchuk

Department of Biochemistry: Faculty Publications

Remodeling of mitochondrial ultrastructure is a process that is critical for organelle physiology and apoptosis. Although the key players in this process—mitochondrial contact site and cristae junction organizing system (MICOS) and Optic Atrophy 1 (OPA1)—have been characterized, the mechanisms behind its regulation remain incompletely defined. Here, we found that in addition to its role in mitochondrial division, metallopeptidase OMA1 is required for the maintenance of intermembrane connectivity through dynamic association with MICOS. This association is independent of OPA1, mediated via the MICOS subunit MIC60, and is important for stability of MICOS and the intermembrane contacts. The OMA1-MICOS relay is required …

Trident - Spring 2021, Dugoni School Of Dentistry

Trident

The newsletter of the Pacific Orthodontic Alumni Chapter at University of the Pacific, Arthur A. Dugoni School of Dentistry. This issue is dedicated to the memory of our late Dean Emeritus Dr. Dugoni.

Biodegradable Cellulose Film Prepared From Banana Pseudo-Stem Using An Ionic Liquid For Mango Preservation, Binling Ai, Lili Zheng, Wenqi Li, Xiaoyan Zheng, Yang Yang, Dao Xiao, Jian Shi, Zhanwu Sheng

Biosystems and Agricultural Engineering Faculty Publications

The excessive use and disposal of plastic packaging materials have drawn increasing concerns from the society because of the detrimental effect on environment and ecosystems. As the most widely used fruit packing material, polyethylene (PE) film is not suitable for long-term preservation of some tropical fruits, such as mangos, due to its inferior gas permeability. Cellulose based film can be made from renewable resources and is biodegradable and environmental-friendly, which makes it a promising alternative to PE as a packaging material. In this study, cellulose film synthesized from delignified banana stem fibers via an ionic liquid 1-Allyl-3-methylimidazolium chloride ([AMIm][Cl]) were …

2021 February 19 - Board Of Trustees Agenda And Minutes, Board Of Trustees, East Tennessee State University

Board of Trustees Agendas and Minutes

No abstract provided.

Rsif Weekly Vol.2 No.6 - Benin Outperforms Rest With Women Engineers, Regional Scholarship And Innovation Fund (Rsif)

Rsif Newsletters

No abstract provided.

Whole-Exome Sequencing And Hipsc Cardiomyocyte Models Identify Myrip, Trappc11, And Slc27a6 Of Potential Importance To Left Ventricular Hypertrophy In An African Ancestry Population, Marguerite R. Irvin, Praful Aggarwal, Steven A. Claas, Lisa De Las Fuentes, Anh N. Do, C. Charles Gu, Andrea Matter, Benjamin S. Olson, Amit Patki, Karen Schwander, Joshua D. Smith, Vinodh Srinivasasainagendra, Hemant K. Tiwari, Amy J. Turner, Deborah A. Nickerson, Dabeeru C. Rao, Ulrich Broeckel, Donna K. Arnett

Epidemiology and Environmental Health Faculty Publications

Background: Indices of left ventricular (LV) structure and geometry represent useful intermediate phenotypes related to LV hypertrophy (LVH), a predictor of cardiovascular (CV) disease (CVD) outcomes.

Methods and Results: We conducted an exome-wide association study of LV mass (LVM) adjusted to height^2.7, LV internal diastolic dimension (LVIDD), and relative wall thickness (RWT) among 1,364 participants of African ancestry (AAs) in the Hypertension Genetic Epidemiology Network (HyperGEN). Both single-variant and gene-based sequence kernel association tests were performed to examine whether common and rare coding variants contribute to variation in echocardiographic traits in AAs. We then used a data-driven …

Oxidation Chemistry Of Catechol Utilized In Designing Stimuli-Responsive Adhesives And Antipathogenic Biomaterials, Rattapol Pinnataip, Bruce Lee

Michigan Tech Publications, Part 1

Mussel foot proteins (Mfps) contain a large amount of the catecholic amino acid, DOPA, allowing the marine organism to anchor themselves onto various surfaces in a turbulent and wet environment. Modification of polymers with catechol imparts these materials with a strong, wet adhesive property. The oxidation chemistry and oxidation state of catechol are critical to the design of synthetic adhesives and biomaterials. In this Mini-Review, the effect of catechol oxidation state on adhesion, oxidation-mediated catechol cross-linking, and the generation of reactive oxygen species (ROS) during catechol oxidation are reviewed. Finally, the tuning of catechol oxidation state in designing stimuli-responsive adhesives …

2021 February 19 - Board Of Trustees Academic, Research, And Student Success Committee Agenda And Minutes, Board Of Trustees, East Tennessee State University

Board of Trustees Agendas and Minutes

No abstract provided.

Kenyon Collegiate - February 19, 2021

Kenyon Collegiate

No abstract provided.