Digital Commons Network^™

Evidence Of Western Corn Rootworm (Diabrotica Virgifera Virgifera Leconte) Field-Evolved Resistance To Cry3bb1 + Cry34/35ab1 Maize In Nebraska, Jordan Reinders, Emily E. Reinders, Emily Robinson, Brian W. French, Lance J. Meinke

Department of Entomology: Faculty Publications

BACKGROUND: Western corn rootworm (WCR; Diabrotica virgifera virgifera) field-evolved resistance to transgenic maize expressing the Cry3Bb1 protein derived from Bacillus thuringiensis (Bt) has been confirmed across the United States Corn Belt. Although use of pyramided hybrids expressing Cry3Bb1 + Cry34/35Ab1 has increased in recent years to mitigate existing WCR Bt resistance, susceptibility of Nebraska WCR populations to this rootworm–Bt pyramid has not been assessed. Plant-based bioassays were used to characterize the susceptibility of WCR populations to Cry3Bb1 and Cry3Bb1 + Cry34/35Ab1 maize. Populations were collected from areas of northeastern Nebraska with a history of planting Bt maize that expressed Cry3Bb1 …

Design, Synthesis, And Catalytic Application Of Crystalline Porous Nanomaterials, Zainab Abdullah Almansaf

Graduate Theses and Dissertations

Chapter 1: COFs (covalent organic frameworks) are a new type of microporous crystalline polymer connected by organic units via strong covalent bonds. Due to their well-defined crystalline structures and excellent chemical and thermal stabilities, COF materials are considered promising candidates in applications such as gas adsorption, catalysis, and energy storage.Chapter 2: A new covalent organic framework (COF) based on imine bonds was assembled from 2-(4-formylphenyl)-5-formylpyridine and 1,3,6,8-tetrakis(4-aminophenyl)pyrene, which showed an interesting dual-pore structure with high crystallinity. Postmetallation of the COF with Pt occurred selectively at the N donor (imine and pyridyl) in the larger pores. The metalated COF served as …

Factors That Influence The Extent To Which Cities On Florida’S Atlantic Coast Are Preparing For Climate Change: A Multiple Regression Analysis And Learning Opportunities For Policymakers, Sheila Ann Young

Theses and Dissertations

This study involved a survey (Appendix A) to leaders of 158 cities inside the counties that border the Atlantic coast of Florida. The impetus behind this study was to identify how policymakers were obtaining, understanding, and sharing information about climate change in order to help inform the policymaking process about adaptation. We cannot only train students at the secondary and university levels about climate change and expect policies to change right away. Those students, for the most part, will not be in policymaking leadership positions for years or decades. What is needed now are strategies to address the climate change …

Variations In Otolith-Zinc Concentrations Of Brown Surgeonfish (Acanthurus Nigrofuscus) Between Marine Protected Areas And Fished Reefs, Matthew Austin Nichols

Theses and Dissertations

As human populations continue to increase, the growing reliance on exploited fish stocks has furthered patterns of declining body size and biomass worldwide. To mitigate these impacts, fisheries managers have implemented a variety of conservation strategies, including marine protected areas (MPA), as these serve as a refuge for fish, resulting in increases in numerous health metrics (fish density, biomass, body-size, and species diversity). By using fish otolith samples previously concluded to have physiological and morphometric differences between MPA and fished reef (FR) fish, this thesis explores the potential of using microchemical analysis of zinc (Zn) to reveal impacts MPAs might …

Characteristics Of Substance Addicted Mothers That Predict Graduation From The Family Treatment Court, Katherine Barnett

Doctorate of Nursing Science Dissertations

In the United States, substance addiction is a major contributing factor to incarceration of mothers and separation of children from their families. Five hundred Family Treatment Courts (FTC) operate across the country to combat the growing problem of women addicted to drugs. The FTC model provides mothers with substance addiction treatment, intensive judicial monitoring, repeated drug testing, counseling, incentives or sanctions, and case management with the goal of reaching long term sobriety and reunification with their children. Understanding characteristics that may influence graduation from the Family Treatment Court will provide valuable information on developing interventions to support participants’ success and …

Alterations In Excitatory And Inhibitory Synaptic Development Within The Mesolimbic Dopamine Pathway In A Mouse Model Of Prenatal Drug Exposure, Taylor Boggess, James C. Williamson, Ethan B. Niebergall, Hannah Sexton, Richard D. Egleton, Larry Grover, Chris Risher

Biomedical Sciences

The rise in rates of opioid abuse in recent years in the United States has led to a dramatic increase in the incidence of neonatal abstinence syndrome (NAS). Despite improved understanding of NAS and its acute symptoms, there remains a paucity of information regarding the long-term effects of prenatal exposure to drugs of abuse on neurological development. The primary goal of this study was to investigate the effects of prenatal drug exposure on synaptic connectivity within brain regions associated with the mesolimbic dopamine pathway, the primary reward pathway associated with drug abuse and addiction, in a mouse model. Our secondary …

The Medium-Term Impacts Of Integrated Crop–Livestock Systems On Crop Yield And Economic Performance, Teerath Singh Rai, Thandiwe Nleya, Sandeep Kumar, Peter Saxton, Tong Wang, Yubing Fan

Agronomy, Horticulture and Plant Science Faculty Publications

Integrated crop–livestock (ICL) systems are diverse production systems that can improve resource utilization through spatially or temporally rotating land among crop, livestock, and pasture uses. However, research on whether the enhanced resource utilization translates to greater crop productivity is still warranted. A field experiment was initiated at South Dakota State University in 2016 to determine the impacts of integrating cover crops and livestock grazing into a crop rotation of oat (Avena sativa L.)–maize (Zea mays L.)–soybean [Glycine max (L.) Merr.]. The objectives were to (a) determine the medium-term (4–6 yr) impacts of cover crops and livestock grazing …

Longitudinal Monitoring Of Tumor Response To Immune Checkpoint Inhibitors Using Diffuse Optical Spectroscopy, Joel Isaac Rodriguez Troncoso

Graduate Theses and Dissertations

Immune checkpoint drugs have completely changed the way people treat metastatic melanoma and non-small-cell lung cancer. While the impacts of these immunological checkpoints and their suppression on T cell function are well characterized, their consequences on the tumor microenvironment are not. In a CT26 mouse colorectal cancer model, we employed diffuse reflectance spectroscopy to track in vivo tumor microenvironmental alterations in response to immune checkpoint inhibitors. On three separate days, animals bearing CT26 tumor xenografts were given anti-PD-L1, anti-CTLA-4, a combination of both inhibitors, and isotype control. Within the first 6 days, monotherapy with either anti-PD-L1 or anti-CTLA-4 resulted in …

Building Energy Model Simulation Of A Single Building In Comparison To A Broader Building Stock, Paola Michelle Santillano

Open Access Theses & Dissertations

Residential facilities and buildings are the largest consumers of energy in the United States. More than 76% of electricity and more than 40% of all energy consumption comes from providing a comfortable and healthy environment in buildings. Prioritizing building energy technology goals for performance and cost can significantly reduce energy use within the next ten years despite a substantial forecasted population increase. Retrofitting existing buildings and improving future construction has the potential to realize cost savings and environmental benefits over time. A key component to realizing these benefits is regional building energy modeling. One of the challenges to widespread building …

Long-Term Effects Of Adolescent Fluoxetine Exposure On Hippocampal Gene Expression In Male C57bl/6 Mice, Anapaula Themann

Open Access Theses & Dissertations

Mood-related disorders, including depression and anxiety, are prevalent among children and adolescents. This poses a public health challenge, given their adverse impact on these young populations. Treatment with the selective serotonin reuptake inhibitor fluoxetine (FLX) is the first line of pharmacological intervention in pediatric patients suffering from affect-related illnesses. Although the use of this antidepressant has been deemed efficacious in the juvenile population, the enduring neurobiological consequences of adolescent FLX exposure are not well understood. For this reason, we explored for persistent molecular adaptations, in the adult hippocampus, as a function of adolescent FLX pretreatment. To do this, we administered …

Identification Of Prostate Cancer-Associated Genomic Alterations By Analyzing Variant Frequencies, Functional Effects, And Protein Interactions, Bofei Wang

Open Access Theses & Dissertations

With the ever-increasing varieties of sequencing techniques, the volume and scope of genomic data are explosively expanded, offering unparalleled opportunities for researchers to study gene-disease associations, identify biomarkers, and thus develop more effective diagnostic and therapeutic strategies. In this project, I have developed a computational workflow and a new scoring scheme, which combine statistical frequency-based analyses with two well-established functional effect prediction tools FATHMM and PROVEAN, to evaluate nonsynonymous GSVs and identify potential cancer-related protein-coding genes for downstream enrichment and protein-protein interaction (PPI) studies.

This method has been applied to process a collection of 503 whole exome sequencing datasets for …

The Posthuman Paradox: Acknowledging What Matters Through Affective Rhetoricity, Alison Wells Zepeda

Open Access Theses & Dissertations

This dissertation advances a theory of affective rhetoricity through personal narrative and an integrative literature review as a methodological approach. The project draws on a theoretical framework constructed from intra- and extra-disciplinary theories of posthumanism, affect, language, material feminism, object-oriented ontology, new materialism, and rhetoric through which collisions between objects and language are examined as arguments for affective rhetoricity as a revised way of understanding rhetoric’s force. The study culminates with ethical and pedagogical implications for the rhetoric and writing classroom, what it means to enact an ontological disposition toward writing, and an exploration of our human capacity to write …

A Integrated Approach Of Deep Learning And Augmented Reality For Pneumonia Detection In Chest X-Ray Images, Jeevarathinam Senthilkumar

Open Access Theses & Dissertations

Pneumonia is a viral or fungal illness that spreads to the lungs of the human body, causing fluid to accumulate in the lungs' air sacs. Millions of people are affected by this disease each year. One of the most common radiological diagnostics for diagnosing and screening this kind of sickness is a chest X-ray. The most commonly available radiological test for diagnosing and screening this kind of illness is a chest X-ray. An inaccurate diagnosis, especially over-diagnosis and under-diagnosis, is a common issue in the medical sector. As another issue, human-assisted diagnosis has limitations like the availability of an expert, …

Computational Study Of Grain Structure Evolution In Cdte/Cds Via Molecular Dynamics, Sharmin Abdullah

Open Access Theses & Dissertations

Grain structure analysis plays an important role in the identification of grain boundary characteristics, which can affect the efficiency of Cadmium Telluride/Cadmium Sulfide (CdTe/CdS) solar cells since they can act as recombination centers for carriers. Computer simulations such as molecular dynamics (MD) can be a very convenient and cost- effective method of investigating the growth evolution and grain structure of materials. The recently reported and experimentally validated MD simulated growth of polycrystalline CdTe/CdS films shows that these materials mostly consist of zinc blende (ZB) and wurtzite (WZ) structures, along with highly disordered atoms. However, little information about the semiconductor compound …

The Physiological Factors Of Diabetes And Their Effect On The Cognitive And Emotional Functioning In Older Populations: A Secondary Data Analysis, Celeste Anahi Alvidrez

Open Access Theses & Dissertations

Background: The rates of Type 2 Diabetes (T2D) have increased over the past 20 years in all age groups. The physiological factors that underlie T2D could have impact on specific brain pathways that support cognitive and emotional functioning. Aims and Objective: The goal of this study was to examine whether older Mexican American individuals with a history of T2D were more likely to develop later cognitive impairment and/or depression. Hypotheses: It was predicted that elderly participants (mean age at time of interview = 87.87 years) with a history of T2D onset prior to age 65, are more likely to have …

Examination Of The Association Between C - Reactive Protein(Crp) And Covid-19 Infection Severity And Length Of Hospitalization, Abdulahi Aremu Ayanwale

Open Access Theses & Dissertations

Chronic stress can lead to many systemic complications and low-grade systemic inflammation including increased levels of inflammatory cytokines, such as C-reactive protein (CRP). CRP is a marker of systemic inflammation and is associated with depression and perceived stress. Elevations can result in ineffective immune responses, thereby increasing the risk of complications and mortality from infections. Recent evidence suggests that uncontrolled inflammatory responses associated with COVID 19 are a major determinant of disease severity.  The COVID 19 is transmitted from one person to another through droplets from coughing, sneezing, talking, touching droplets on surfaces and contamination by hand-to-mouth routes. The mechanism …

Cell Bioprinting: A Novel Approach For Alpha Cell To Beta Cell Transdifferentiation, Atzimba Casas

Open Access Theses & Dissertations

Diabetes is a chronic disease that occurs in the body when the pancreas fails to either produce insulin (TID) or does not effectively use the insulin produced (TIID) and poses further health complications as well as an insurmountable economic impact.[1] Type I diabetes is an autoimmune disease characterized by a deficient amount of insulin production on account of the body’s immune system destroying its own β-cells.[2] Current diabetes treatment methods include the administration of insulin via injections or islet transplantation therapy. However, although both are viable options, they come with limitations that make the managing of this disease difficult. It …

Development Of Metaheuristic Algorithms For The Efficient Allocation Of Power Flow Control Devices, Eduardo Jose Castillo Fatule

Open Access Theses & Dissertations

Modern energy grids have become extremely complex systems, requiring more variable and active flow control. As a remedy to this, Distributed Flexible AC Transmission Systems (D-FACTS) are cost-efficient devices used to mitigate power flow congestion and integrate renewable energies. The objective of this research is then to propose an efficient multiple objective evolutionary algorithm to solve a stochastic model for D-FACTS allocation, which aims to optimize various objectives related to cost, grid health, and environmental impacts. The model was implemented on a modified RTS-96 test system, and the results show that optimally allocating D-FACTS modules using the proposed model can …

In Vitro Investigation Of Tumor Selective Piperidones As Therapeutic Agents Against Leukemia Cancer Cells, Lisett Contreras

Open Access Theses & Dissertations

Cancer is a continuous global health issue. It is the second leading cause of death behind heart disease. Disparities across the emergence of cancer and resulting fatalities raise the importance of researching the disease. Treatments are available for certain types of cancers. However, these are typically accompanied by residual problems including side effects and the possibility for relapse. Some treatments attack all cells, leading to unwarranted side effects that make the possibility of living a comfortable life nearly impossible. Other treatments are specific to certain genetic alterations, making them only useful for a small percentage of patients. Not one treatment …

Effects Of Coated/Uncoated Copper-Based Nanoparticles And Compounds On Rice (Oryza Sativa) And Soybean (Glycine Max) Plants, Chaoyi Deng

Open Access Theses & Dissertations

Engineering nanoparticles (ENPs) have been widely used in industry due to their promising chemical, physical, electrical, magnetic, optical, and electronic properties. Copper-based ENPs are used as gas sensors, catalysts, semiconductors and agricultural products, among others. Because of their antifungal and antibacterial properties, they are used in agriculture as insecticides, herbicides and antifungal agents. Due to their mass production and use, ENPs are likely to be ubiquitous in our in the environment in the near future. In addition, metal nanoparticles are usually coated with organic compounds to enhance the properties of the nanoparticles. Previous studies have shown that copper-based ENPs can …

Linking Plot And Landscape Level Phenology, Alejandra Flores

Open Access Theses & Dissertations

Plant phenology has become popularize since the 1990s to help understand the effects of climate change on vegetation, it is a way to study the patterns of leaf-out, flowering, and senescing of the life-cycle of the plant. The timing from start of season (SOS) to end-of-season (EOS) of plant leaf-out development has important implication on ecosystem productivity and carbon cycling across ecological scales from individual trees to whole regions. The need for plant phenology studies in dryland are highly anticipated, since they make up 40% of the terrestrial landscape and recently have shown the play an important role in the …

Student Attitudes Toward Science: Growth Trajectories And Thematic Analysis Of A Project-Based Internship, Robert Donavin Mccreary

Open Access Theses & Dissertations

In order to increase the number of students pursuing science-related careers, science educators and policymakers have advocated for improving student attitudes toward science (SAS) through inquiry-based instruction, such as project-based learning (PBL). While challenges exist in PBL, research suggests cogenerative dialogue (cogen) can ease the transition for students from traditional learning to PBL. In the present study, a secondary analysis was conducted to examine SAS growth trajectories from participants of the Work With A Scientist Program (WWASP) – a student-scientist internship which integrated cogen with PBL. Additionally, a thematic analysis was conducted to explore student attitudes toward cogen. The growth …

Study Of Barrier Heights And Magnetic Property Using Locally Scaled And Perdew-Zunger Self-Interaction Methods, Prakash Mishra

Open Access Theses & Dissertations

Kohn-Sham density functional theory is a widely used method to estimate the ground state total energies and densities of interacting correlated electronic structures of atoms, molecules, clusters, solids, and liquids. In theory, exact solutions for these properties can be obtained by solving self-consistent one-electron Schrodinger equations based on density functionals for the energy.The practical application of KS DFT require approximation to the exchange-correlation energy functional. Many density functional approximations (DFAs) have been developed with various degree of sophistication and complexity by the satisfaction of exact constraints. Depending on the complexity, these functionals include electron density, density gradients, density Laplacian, kinetic …

Leading In Gendered Spaces: Women Presidents' Perceptions Of Their Experiences In Community Colleges, Keri Moe

Open Access Theses & Dissertations

Gender inequality in leadership is an ongoing challenge found in higher education, including community colleges. Since women remain underrepresented in leadership positions at community colleges, specifically as college presidents, the purpose of this study was to document and better understand the experiences of women in these roles by focusing on three research questions:

• RQ 1: How do women presidents describe their experience in male-dominated community colleges?
• RQ 2: How do gender identity and gender expectations of women impact the behavior of women community college presidents?
• RQ 3: How do women presidents navigate their role within male-dominated community colleges?

Through the …

Evaluation Of Varying Graphene Oxides Through Their Physicochemical Characterizations On Erythrocytes, Hs27 Cells, Escherichia Coli And Staphylococcus Aureus Bacteria Cell Lines, To Assess Graphene Oxides Cytotoxicity., Miriam Montana

Open Access Theses & Dissertations

Research on the toxicity of Graphene Oxides (GO) has captivated interest in the field of material science, environmental sciences, and medicine for their avail significance in biomedical engineer applications either as integrates, enhancements, or in the making of medical devices. Moreover, there is still a lack of understanding as to what characteristics on GOs causes them to be cytotoxic at a cellular level. In our study we synthesized four different GOs by varying in both the method used for oxidation (Modified Hummer’s method & Improved Marcano-Tour’s method), and the precursor parent graphite, for a standardization approach to aid in the …

Carbon Fiber Electrodes For Intracellular Recording And Stimulation, Yu Huan, Jeffrey P. Gill, Hillel J. Chiel

Faculty Scholarship

Objective. To understand neural circuit dynamics, it is critical to manipulate and record many individual neurons. Traditional recording methods, such as glass microelectrodes, can only control a small number of neurons. More recently, devices with high electrode density have been developed, but few of them can be used for intracellular recording or stimulation in intact nervous systems. Carbon fiber electrodes (CFEs) are 8 µm-diameter electrodes that can be assembled into dense arrays (pitches 80 µm). They have good signal-to-noise ratios (SNRs) and provide stable extracellular recordings both acutely and chronically in neural tissue in vivo (e.g. rat motor cortex). The …

Sociocultural And Psychological Acculturation Strategies Of South African International Students In A Flemish University In Belgium: A Photovoice Study

Journal of Comparative & International Higher Education

No abstract provided.

Plant Disease Detection Through Convolutional Neural Networks: A Survey Of Existing Literature, Best Practices, And Implementation, Kevin Label

Master's Theses

In the United States alone, common diseases spread among plants account for billions of dollars lost in crop yield each year. This issue is exacerbated in countries with less infrastructure to defend against crop epidemics, and can lead to famine and forced migration. Farmers can seek the help of plant pathology experts to defend against diseases and detect crop irregularities early on. However, access to experts can be difficult, and even those trained in the field may miss symptoms before it is too late. To assist in early disease detection, a number of papers have been released on the potential …

Ftc Orders Destruction Of Algorithms Created From Unlawfully Acquired Data, Randi W. Singer, Michael Goodyear

Articles & Chapters

No abstract provided.

It's Intense: A Mixed Methods Study Of Student Stress In Pta Education, Gina Tarud, Beverly A. Labosky, Laura Cruz, Nicole Paranich, Brian Thomas

Health Professions Education

Purpose. This study was implemented to measure the self-reported factors contributing to student stress and anxiety levels and the strategies employed to navigate these stressors.

Methods. This study utilized a mixed method design for collecting and analyzing both quantitative and qualitative data to identify the trends and details of the complex learning environment of the Physical Therapist Assistant (PTA) students. Current enrolled students within a Physical Therapist Assistant program were invited to participate in this study. A survey was created to gather the data using Qualtrics and a link was distributed via their university email.

Results. This study explored the …