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2021

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Assessment Of The Level Of Compliance Of Women Of Uzbekistan With A Healthy Lifestyle, Durdona M. Akhmedova, Adiba A. Usmankhodjaeva, Ulugbek A. Sharipov Dec 2021

Assessment Of The Level Of Compliance Of Women Of Uzbekistan With A Healthy Lifestyle, Durdona M. Akhmedova, Adiba A. Usmankhodjaeva, Ulugbek A. Sharipov

Central Asian Journal of Medicine

In January 2021, in order to assess the level of healthy living of the women of Uzbekistan, i.e. the observance of a healthy lifestyle, to identify many common diseases and problems among women, we conducted mass medical examinations (anthropometric examinations) among women in Namangan and and Andijan cities. 276 women (aged 46-74 years) took part in the medical examination. We have studied all 276 women with age, gender, hereditary diseases, concomitant diseases, and have analyzed and evaluated them based on several principles. We put the data obtained into tables and diagrams so that it is easy to analyze. From the …


Development Of An Innovative Computer-Information Apparatus For Designing And Implementing An Integrated Model Of Training And Activity Of A Specialist In Medical Universities, Axmat F. Marasulov, Muratali I. Bazarbayev, Erkinbay Ya. Ermetov Dec 2021

Development Of An Innovative Computer-Information Apparatus For Designing And Implementing An Integrated Model Of Training And Activity Of A Specialist In Medical Universities, Axmat F. Marasulov, Muratali I. Bazarbayev, Erkinbay Ya. Ermetov

Central Asian Journal of Medicine

It is proposed to develop an integrated model of training a future specialist based on the construction and implementation of: an integrated conceptual and theoretical apparatus for the activities of a teacher and a student, a functionally task-oriented hierarchical system of an educational and methodological knowledge base and a database for training a specialist, department computer and information technology for managing the training of a future specialist. Computer-information technology of the integrated apparatus of conceptual and theoretical activity of the teacher and student, based on the disclosure of the content and structure of methodological knowledge of the teacher associated with …


Features Of Dermatological Manifestations After Coronavirus Infection In Patients With Previously Intact Skin, Umida A. Tashkenbaeva, Guzal D. Klebleeva Dec 2021

Features Of Dermatological Manifestations After Coronavirus Infection In Patients With Previously Intact Skin, Umida A. Tashkenbaeva, Guzal D. Klebleeva

Central Asian Journal of Medicine

Being a relatively new pathology, coronavirus infection, due to the multiple organ damage to the body, has many clinical manifestations, including dermatological ones, the study of which is still the subject of research. Since its spread, there have been very few reports of dermatological manifestations of COVID-19 and its cutaneous manifestations in the community. Purpose of the study: is to identify the features of the clinical course of dermatological manifestations in patients who have undergone coronavirus infection. Materials and methods: The study included 108 patients who underwent a comprehensive examination and treatment in the Samarkand regional dermatovenerologic dispensary from July …


Disfunction Of Vascular Endothelium As A Pathogenetic Factor Of The Development Of Thrombophilic Conditions In Chronic Obstructive Pulmonary Disease (Review), Elnora A. Abduganieva, Irina V. Liverko, Rano K. Dadabaeva Dec 2021

Disfunction Of Vascular Endothelium As A Pathogenetic Factor Of The Development Of Thrombophilic Conditions In Chronic Obstructive Pulmonary Disease (Review), Elnora A. Abduganieva, Irina V. Liverko, Rano K. Dadabaeva

Central Asian Journal of Medicine

In world medicine, the problem of cardiopulmonary comorbidity, including the development of thrombotic cardiovascular catastrophes against the background of chronic obstructive pulmonary disease (COPD), is becoming increasingly important. Endothelial dysfunction, developing as a result of changes in the underlying pathogenesis of COPD, can increase the predisposition to cardiovascular complications - thrombosis in this group of patients. The purpose. The aim of this study was to analyze the available scientific data on the possible role of endothelial dysfunction in the high incidence of thrombotic complications in COPD. Material and research methods. The research material was the open access scientific literature of …


Results Of Morphological Studies Of Various Forms Of Chronic Tonsillitis, Firdavs N. Nordjigitov, Jamolbek A. Djuraev Dec 2021

Results Of Morphological Studies Of Various Forms Of Chronic Tonsillitis, Firdavs N. Nordjigitov, Jamolbek A. Djuraev

Central Asian Journal of Medicine

Traditionally, the diagnosis of chronic tonsillitis is based on the assessment of clinical signs. It should also be born in mind that the morphological examination of the tonsils is an invasive method and can only be used to confirm the diagnosis after tonsillectomy, and not as a routine examination of patients with chronic tonsillitis. Morphological changes in palatine tonsils during chronic tonsillitis are represented by the proliferation of connective tissue in the thickness of the lymphoid tissue, the presence of necrotic foci, damage to the walls of capillary vessels, and disturbances in the crypt epithelium. In the case of the …


Epidemiology Of Benign Prostate Hyperplasia And The Importance Of Risk Factors In The Development Of Pathology (On The Example Of Andijan), Alisher A. Shadmanov, Akramjon R. Saliev, Feruza I. Salomova Dec 2021

Epidemiology Of Benign Prostate Hyperplasia And The Importance Of Risk Factors In The Development Of Pathology (On The Example Of Andijan), Alisher A. Shadmanov, Akramjon R. Saliev, Feruza I. Salomova

Central Asian Journal of Medicine

Aim of the study: the prevalence of benign prostate hyperplasia and the importance of risk factors in the development of pathology among the unorganized male population in Andijan was analyzed. Materials and methods: the total volume of the competition was 2702 people, and the survey coverage was 1977 people (72.3%). Conclusions: benign prostatic hyperplasia was registered in 844 (42.7%) people, the lowest rate was in the age group 30-39 years old, and the highest in the age group 50-59 years old (28.4%). The results of the assessment of the main risk factors for the development of prostatic hyperplasia showed that …


Study Of Apparent Molar Volumes Of Electrolyte Solutions And Its Application In Medicine, Muratali I. Bazarbayev, Qumrijon I. Narziqulova, Islom Mullojonov, Erkinbay Ya. Ermetov Dec 2021

Study Of Apparent Molar Volumes Of Electrolyte Solutions And Its Application In Medicine, Muratali I. Bazarbayev, Qumrijon I. Narziqulova, Islom Mullojonov, Erkinbay Ya. Ermetov

Central Asian Journal of Medicine

All biological processes in plant or animal organisms, including in the human body, are carried out in solutions. Therefore, the progress of sciences such as biology, medicine, etc., is closely related to the development of the doctrine of solutions. When dissolved, various chemical interactions occur between the components and due to Van der Waals force, etc. One of the methods for determining the ion molecular interaction is the study of the partial molar volume of electrolytes.


Complement-Mediated Selective Tumor Cell Lysis Enabled By Bi-Functional Rna Aptamers, Hua Shi, Prabhat K. Mallik, Kimi Nishikawa, Pramit Mallik Dec 2021

Complement-Mediated Selective Tumor Cell Lysis Enabled By Bi-Functional Rna Aptamers, Hua Shi, Prabhat K. Mallik, Kimi Nishikawa, Pramit Mallik

Biological Sciences Faculty Scholarship

Unlike microbes that infect the human body, cancer cells are descended from normal cells and are not easily recognizable as “foreign” by the immune system of the host. However, if the malignant cells can be specifically earmarked for attack by a synthetic “designator”, the powerful effector mechanisms of the immune response can be conscripted to treat cancer. To implement this strategy, we have been developing aptamer-derived molecular adaptors to invoke synthetic immune responses against cancer cells. Here we describe multi-valent aptamers that simultaneously bind target molecules on the surface of cancer cells and an activated complement protein, which would tag …


Implications Of Salinity Normalization Of Seawater Total Alkalinity In Coral Reef Metabolism Studies, Travis A. Courtney, Tyler Cyronak, Alyssa J. Griffin, Andreas J. Andersson Dec 2021

Implications Of Salinity Normalization Of Seawater Total Alkalinity In Coral Reef Metabolism Studies, Travis A. Courtney, Tyler Cyronak, Alyssa J. Griffin, Andreas J. Andersson

Marine & Environmental Sciences Faculty Articles

Salinity normalization of total alkalinity (TA) and dissolved inorganic carbon (DIC) data is commonly used to account for conservative mixing processes when inferring net metabolic modification of seawater by coral reefs. Salinity (S), TA, and DIC can be accurately and precisely measured, but salinity normalization of TA (nTA) and DIC (nDIC) can generate considerable and unrecognized uncertainties in coral reef metabolic rate estimates. While salinity normalization errors apply to nTA, nDIC, and other ions of interest in coral reefs, here, we focus on nTA due to its application as a proxy for net coral reef calcification and the importance for …


Dynamic Relationship Study Between The Observed Seismicity And Spatiotemporal Pattern Of Lineament Changes In Palghar, North Maharashtra (India), Biswajit Nath, Ramesh P. Singh, Vineet K. Gahalaut, Ajay P. Singh Dec 2021

Dynamic Relationship Study Between The Observed Seismicity And Spatiotemporal Pattern Of Lineament Changes In Palghar, North Maharashtra (India), Biswajit Nath, Ramesh P. Singh, Vineet K. Gahalaut, Ajay P. Singh

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The Palghar region (north Maharashtra, India), located in the northwestern part of the stable continental region of India, experienced a low magnitude earthquake swarm, which was initiated in September 2018 and is continuing to date (as of October 2021). From December 2018 to December 2020, ~5000 earthquakes with magnitudes from M1.2 to M3.8 occurred in a small region of 20 × 10 km2. These earthquakes were probably triggered by fluid migration during seasonal rainfall. In this study, we have used multi-temporal Landsat satellite data of the year 2000, 2015, 2018, 2019, and 2020, extracted lineaments, and studied the …


Deep Learning Supplants Visual Analysis By Experienced Operators For The Diagnosis Of Cardiac Amyloidosis By Cine-Cmr, Philippe Germain, Armine Vardazaryan, Nicolas Padoy, Aissam Labani, Catherine Roy, Thomas Hellmut Schindler, Soraya El Ghannudi Dec 2021

Deep Learning Supplants Visual Analysis By Experienced Operators For The Diagnosis Of Cardiac Amyloidosis By Cine-Cmr, Philippe Germain, Armine Vardazaryan, Nicolas Padoy, Aissam Labani, Catherine Roy, Thomas Hellmut Schindler, Soraya El Ghannudi

Open Access Publications

BACKGROUND: Diagnosing cardiac amyloidosis (CA) from cine-CMR (cardiac magnetic resonance) alone is not reliable. In this study, we tested if a convolutional neural network (CNN) could outperform the visual diagnosis of experienced operators.

METHOD: 119 patients with cardiac amyloidosis and 122 patients with left ventricular hypertrophy (LVH) of other origins were retrospectively selected. Diastolic and systolic cine-CMR images were preprocessed and labeled. A dual-input visual geometry group (VGG ) model was used for binary image classification. All images belonging to the same patient were distributed in the same set. Accuracy and area under the curve (AUC) were calculated per frame …


Top Ole Miss News Stories Of 2021, Staff Report Dec 2021

Top Ole Miss News Stories Of 2021, Staff Report

University of Mississippi News

Relive a year of accolades and achievements at the university


Fungicidal Effects Of Homoeopathic Medicines Versus Allopathic Ketoconazole In Candida Albicans, Chiara X. Mercado, Brandy Garrett Kluthe Dec 2021

Fungicidal Effects Of Homoeopathic Medicines Versus Allopathic Ketoconazole In Candida Albicans, Chiara X. Mercado, Brandy Garrett Kluthe

Indian Journal of Research in Homoeopathy

Background: Candida albicans, accounts for more than 75% of all Candidal infections. Apart from its growing prevalence, it is also one of the most resistant strains against antifungal medication. Homoeopathy is an alternative to allopathic medication and has shown inhibiting fungal growth. Objective: This study was to determine effectiveness of homoeopathic tinctures and medications versus allopathic Ketoconazole in growth inhibition and fungicidal properties against in vitro cultures of C. albicans. Materials and Methods: Efficacy of five antifungal agents were tested for inhibiting fungal growth and their fungicidal properties on cultured C. albicans the agents tested were Eucalyptus globulus and Ocimum …


A Comparison Of Solid Electrolyte Interphase Formation And Evolution On Highly Oriented Pyrolytic And Disordered Graphite Negative Electrodes In Lithium-Ion Batteries, Haoyu Zhu, Joshua A. Russell, Zongtang Fang, Pete Barnes, Lan Li, Corey M. Efaw, Allison Muenzer, Jeremy May, Kailash Hamal, I. Francis Cheng, Paul H. Davis, Eric J. Dufek, Hui Xiong Dec 2021

A Comparison Of Solid Electrolyte Interphase Formation And Evolution On Highly Oriented Pyrolytic And Disordered Graphite Negative Electrodes In Lithium-Ion Batteries, Haoyu Zhu, Joshua A. Russell, Zongtang Fang, Pete Barnes, Lan Li, Corey M. Efaw, Allison Muenzer, Jeremy May, Kailash Hamal, I. Francis Cheng, Paul H. Davis, Eric J. Dufek, Hui Xiong

Materials Science and Engineering Faculty Publications and Presentations

The presence and stability of solid electrolyte interphase (SEI) on graphitic electrodes is vital to the performance of lithium-ion batteries (LIBs). However, the formation and evolution of SEI remain the least understood area in LIBs due to its dynamic nature, complexity in chemical composition, heterogeneity in morphology, as well as lack of reliable in situ/operando techniques for accurate characterization. In addition, chemical composition and morphology of SEI are not only affected by the choice of electrolyte, but also by the nature of the electrode surface. While introduction of defects into graphitic electrodes has promoted their electrochemical properties, how such structural …


The Utilization Of Enzymes And Enzyme Products For Antimicrobial Effects, Brandon Edward Burdette Dec 2021

The Utilization Of Enzymes And Enzyme Products For Antimicrobial Effects, Brandon Edward Burdette

Theses and Dissertations

Bacterial resistance is outpacing the discovery of novel antimicrobials. Therefore, it is essential to look at antimicrobials using novel methods. MTAN is a crucial enzyme for some bacteria such as Helicobacter pylori. Transition state analog inhibitor design and fragment-based drug design are drug design approaches typically used independently, but combining these techniques yields inhibitors that bind tightly and are effective in pM concentrations. We demonstrate the efficacy of the combined techniques by investigating the inhibition of HpMTAN, which is an essential enzyme. Enzyme byproducts can also be effective for causing bacterial cell death, hydrolyzing GsdmD by caspases-1/4/5/11 results in an …


When The Dark Shadow Of Virtual Reality Intrudes Into The Real World : A Study Of Ursula Poznanski’S Young Adult Novel, Erebos, Siriporn Sriwarakan Dec 2021

When The Dark Shadow Of Virtual Reality Intrudes Into The Real World : A Study Of Ursula Poznanski’S Young Adult Novel, Erebos, Siriporn Sriwarakan

Journal of Letters

This paper studies Ursula Poznanski’s Erebos (2010), a German young adult novel, in terms of the concerns it raises about the dangers of and solutions to computer game addiction among young adults. The novel shows   the dominance of the computer game “Erebos,” which uses artificial intelligence (AI) to process the interests and desires of its players. These players are shown attaching themselves to their virtual selves so much that they deny their real-world selves, and are then manipulated by the Erebos AI to commit acts of violence. On the other hand, the novel reveals that such obsession can be solved …


Water-Use Efficiency And Infiltration Under Different Rangeland Conditions And Cultivation In A Semi-Arid Climate Of South Africa, Hennie A. Snyman Dec 2021

Water-Use Efficiency And Infiltration Under Different Rangeland Conditions And Cultivation In A Semi-Arid Climate Of South Africa, Hennie A. Snyman

IGC Proceedings (1977-2023)

The objective of this study was to determine the impact of rangeland in different botanical composition classes (good, moderate and poor), on water-use efficiency (WUE: crude protein produced per unit of evapotranspiration) and soilwater content. The same measurements were also made on an undisturbed bare soil surface and soil cultivated twice per annum. Evapotranspiration was determined by quantifying the soil-water balance equation with the aid of runoff plots and soil-water content measurements done by a neutron hydroprobe. Water-use efficiency declined significantly (P ≤ 0.01) with rangeland degradation. Rangeland in good condition averaged a WUE of 0.28 kg crude protein ha …


Community Structure Of Serrated Tussock (Nassella Trichotoma) Infested Grasslands, Warwick B. Badgery, David R. Kemp, D. L. Michalk, W. Mcg. King Dec 2021

Community Structure Of Serrated Tussock (Nassella Trichotoma) Infested Grasslands, Warwick B. Badgery, David R. Kemp, D. L. Michalk, W. Mcg. King

IGC Proceedings (1977-2023)

Serrated tussock (Nassella trichotoma) is the most serious perennial grass weed in southeastern Australia, extending over more than a million hectares. Previous control techniques using herbicides and oversowing with competitive pastures are no longer feasible in many of the lower fertility, infested areas. New management solutions need to be found, based upon a better understanding of the ecology of this species. A survey was done to determine the community structure of serrated tussock infested grasslands. Winter growing C3 grasses were closely associated with serrated tussock, while C4 perennial grasses appeared not to be. It is not known if …


Valuing The Pasture Resource - Importance Of Perennials In Higher Rainfall Regions Of South Eastern Australia, P. M. Dowling, R. E. Jones, David R. Kemp, D. L. Michalk Dec 2021

Valuing The Pasture Resource - Importance Of Perennials In Higher Rainfall Regions Of South Eastern Australia, P. M. Dowling, R. E. Jones, David R. Kemp, D. L. Michalk

IGC Proceedings (1977-2023)

The premature decline of perennial grass based pastures in southern temperate Australia results in poor productivity and unstable pastures that allow invasion by less desirable weedy species and the potential for soil degradation. The loss of perennial species is attributed to overgrazing arising from an undervaluation of the pasture resource. Resowing pastures is largely uneconomic so maintenance of, or increasing the perennial, is dependent on improved grazing and pasture management practices. A key to changing perceptions is valuing the true worth of the perennial component. Results are presented from a model that takes into account the seasonality of production of …


Using ‘Traps’ (Transect Recording And Processing System) In Woody Weed Control Studies In Australia, P. V. Back Dec 2021

Using ‘Traps’ (Transect Recording And Processing System) In Woody Weed Control Studies In Australia, P. V. Back

IGC Proceedings (1977-2023)

The ‘TRAPS’ (Transect Recording And Processing System) methodology has proven to be a powerful and versatile tool for studying the effects of various woody weed control strategies in studies carried out in Queensland, Australia. ‘TRAPS’ allows the tracking of individual woody plants even when destructive control techniques such as bulldozing, ploughing and burning are used. This methodology also allows the investigator to discriminate between plants present before any treatment is imposed and plants recruited after the treatment.


The Effect Of Organizational Culture On Institutional Excellence Through The Mediating Role Of Strategic Thinking (An Empirical Study On The Palestinian Universities In The Gaza-Strip), Belal Z. Albashiti أستاذ مشارك Dec 2021

The Effect Of Organizational Culture On Institutional Excellence Through The Mediating Role Of Strategic Thinking (An Empirical Study On The Palestinian Universities In The Gaza-Strip), Belal Z. Albashiti أستاذ مشارك

Journal of Al-Azhar University – Gaza (Humanities)

Abstract:

This study aims to analyze and explain the role of organizational culture on the institutional excellence through the mediating role of strategic thinking. Cross sectional data was collected using simple random sample from the employees holding supervisory positions at the Palestinian universities in the Gaza-Strip. The structure equation model (SEM) is designed to explain the studied variables, the findings and analysis shows high level of relative weight for the studied variables and found indirect effect between; the independent variable "Organizational Culture" and the dependent variable "Institutional Excellence". Some important recommendations and some suggestions further studies in the line of …


الأهداف التعليمية الواردة في محتوى الوحدات الخاصة بالفيزياء في منهاج العلوم للصف الثامن في الأردن والولايات المتحدة الأمريكية دراسة تحليلية مقارنة, الهام حسن عبدالكريم ماجستير, حسين عبداللطيف بعارة أستاذ مساعد Dec 2021

الأهداف التعليمية الواردة في محتوى الوحدات الخاصة بالفيزياء في منهاج العلوم للصف الثامن في الأردن والولايات المتحدة الأمريكية دراسة تحليلية مقارنة, الهام حسن عبدالكريم ماجستير, حسين عبداللطيف بعارة أستاذ مساعد

Journal of Al-Azhar University – Gaza (Humanities)

الملخص:

هدفت الدراسة معرفة تصنيف الأهداف التعليمية الواردة في منهاج العلوم للصف الثامن في الأردن والولايات المتحدة الأمريكية, ولتحقيق أهداف الدراسة تم تحليل محتوى وحدات الفيزياء, وقد تكون مجتمع الدراسة وعينته من الوحدات الخاصة بالفيزياء وعددها ثلاث وحدات في الأردن ووحدتان في الولايات المتحدة الأمريكية, وتم تطوير أداة لتحليل محتوى منهاج العلوم من دراسة (Kim& Park,2009), وصنفت الأهداف إلى خمسة معايير: المعرفة العلمية، والاستقصاء العلمي، والاتجاهات العلمية، والعلم والتكنولوجيا والمجتمع، والفلسفة وتاريخ العلم, وتوصلت الدراسة إلى: احتواء منهاج العلوم في الأردن على معرفة علمية بنسبة (56.7%) يليها الاستقصاء العلمي(18.2%) ثم العلم والتكنولوجيا والمجتمع (11.7%), يليها الفلسفة وتاريخ العلم (9.8%), ثم …


The Impact Of Covid-19 Pandemic On The Evolution Of The Saudi House In Riyadh City, Khaled Alqahtani, Mohammad Alissan Dec 2021

The Impact Of Covid-19 Pandemic On The Evolution Of The Saudi House In Riyadh City, Khaled Alqahtani, Mohammad Alissan

Emirates Journal for Engineering Research

Over the past 100 years, the Saudi dwelling has undergone a series of transformations in its form, design, and function. These evolutions were the result of economic, regulatory, intellectual, and many other influences (Bahammam, 2018). During COVID-19 lockdown, people had to live a new lifestyle, practiced learning and working remotely, and had to stay longer hours at home and keep social distance apart. Daily prayers and outdoor leisure were only limited to the confines of the household. Residents had to consider preventive health precautions such as the use of sterilizing tools and allowing for natural ventilation and daylight.

This study …


Exploring The Relationships Among Stoichiometric Coefficients, Number Of Transferred Electrons, Mean Oxidation Number Of Carbons, And Oxidative Ratio In Organic Combustion Reactions, Pong Kau Yuen, Cheng Man Diana Lau Dec 2021

Exploring The Relationships Among Stoichiometric Coefficients, Number Of Transferred Electrons, Mean Oxidation Number Of Carbons, And Oxidative Ratio In Organic Combustion Reactions, Pong Kau Yuen, Cheng Man Diana Lau

Faculty Publications

Combustion reactions, stoichiometry, and redox reactions are some of the basic contents in chemistry curriculum. Although the counting of transferred electrons is critical in redox reactions, assigning mean oxidation number of organic carbons (ONc) is not always easy. Even though the relationship between the oxidative ratio (OR) and ONc is known, the relationship between the number of transferred electrons (Te−) and OR has not been thoroughly studied. The H-atom method has already been developed to balance and deduct organic combustion reactions. It can be used further to help establish the relationships among the stoichiometric coefficients (SC), the number of transferred …


The Question Of Veganism, The Dangers Of Moral Extensionism, And A Pragmatist Ecofeminist Alternative, Erin Mckenna Dec 2021

The Question Of Veganism, The Dangers Of Moral Extensionism, And A Pragmatist Ecofeminist Alternative, Erin Mckenna

Between the Species

In this paper I argue that the framework of moral extensionism relies on human exceptionalism and human centeredness. I discuss the dangers of human exceptionalism and human centeredness using the work of ecofeminist philosophers Val Plumwood, Carol Adams, Lori Gruen, A. Breeze Harper, and Lisa Kemmerer. These ecofeminists each articulate alternative approaches to human relations with other animal beings. There are tensions among these alternatives, though, and I use a pragmatist perspective to interrogate their different positions on how other animal beings should or should not figure into the diets of human beings. I will argue that we need a …


Genome-Wide Analysis Of Methylome In The Mouse Brain Using Long-Read Sequencing Technology, Zachary Even, He Huang, Ramkumar Mathur, Xusheng Wang Dec 2021

Genome-Wide Analysis Of Methylome In The Mouse Brain Using Long-Read Sequencing Technology, Zachary Even, He Huang, Ramkumar Mathur, Xusheng Wang

Arts & Sciences Undergraduate Showcase

DNA methylation is an epigenetic modification that transfers a methyl group onto the C-5 position of the cytosine to form 5-methylcytosine. DNA methylation regulates gene expression by recruiting proteins involved in gene repression or by inhibiting the binding of transcription factor(s) to DNA, especially in regulation of Allele Specific Expression (ASE). In this study, we used Oxford Nanopore long-read sequencing technology to profile methylome in the two inbred mouse strains, C57BL/6J (B6) and DBA/2J (D2). Compared with bisulfite conversion followed by Illumina Sequencing, long-read sequencing technology allows us to achieve much longer read length of 4,653.675 base pairs on average …


Development Of Radiochemical Quality Control Methods For Ra-223 And Th-227 Radiotherapies, Abigail Hasson Dec 2021

Development Of Radiochemical Quality Control Methods For Ra-223 And Th-227 Radiotherapies, Abigail Hasson

McKelvey School of Engineering Graduate Student Theses & Dissertations

Introduction. Radiolabeled molecules for use in disease detection and targeted treatment are a mainstay of patient management. The majority of radiopharmaceuticals deployed to date undergo a single radioactive transition (decay) to reach a stable ground state. Complex emitters, which produce a series of daughter radionuclides, are emerging as novel radiopharmaceuticals, and there is a need for the proper validation of content and purity using common quality control instrumentation. Hypothesis. There is a need for proper characterization of complex emitters for more accurate quality control on readily available equipment. Here, we demonstrate the novel characterization of Th-227 and Ra-223 using a …


Changes Of Volatile Flavor Compounds In Lemon Pulp During Vacuum Freezing, Wang Hai-Ou, Duan Xiao-Jie, Wu Yu-Long, Ben Ai-Ling, Zhang Wei, Hua Chun Dec 2021

Changes Of Volatile Flavor Compounds In Lemon Pulp During Vacuum Freezing, Wang Hai-Ou, Duan Xiao-Jie, Wu Yu-Long, Ben Ai-Ling, Zhang Wei, Hua Chun

Food and Machinery

Objective: The variation characteristics of volatile flavor compounds in lemon pulp during vacuum freezing were investigated in this study, aiming to provide theoretical guidance for the regulation of the volatile flavor quality of the vacuum frozen lemon pulp. Methods: The analysis technologies of the electronic nose (E-nose) and gas-mass spectrometry (GC-MS) were employed to measure the volatile flavor compounds in fresh samples and frozen samples after 10, 20, and 30 minutes of vacuum-freezing, respectively. Results: The results showed that E-nose could be used to analyze different types of volatile flavor compounds in lemon pulp. The samples with different freezing time …


Changes Of Proteolysis And Microstructure Of Dapanji During The Stir-Fried And Stewed Processing, Zhao Dian-Bo, Li Jun-Guang, Liu Hong-Li, Bai Yan-Hong Dec 2021

Changes Of Proteolysis And Microstructure Of Dapanji During The Stir-Fried And Stewed Processing, Zhao Dian-Bo, Li Jun-Guang, Liu Hong-Li, Bai Yan-Hong

Food and Machinery

Objective: It was expected to provide guidance for the improvement of production technology and standardization of industrial production of dapanji. Methods: The intelligent frying machine was used to make Dapanji according to the traditional frying and stewing technique. The contents of free amino acid were measured by amino acid analyzer, Kjeldahl method was used to measure the content of total nitrogen and non-protein nitrogen, the degradation of myofibrillar protein and the transform of microstructure in Dapanji during the stir-fried and stewed processing were investigated by the SDS-PAGE and Scanning electron microscope. Results: The results indicated that the content of free …


The Effect On Nutritional Value And Non-Volatile Flavor Substance Content Of Pleurotus Eryngii With Fermentable Corn Steep Liquor, Li Jing, Zheng Xi-Qun, Liu Xiao-Lan Dec 2021

The Effect On Nutritional Value And Non-Volatile Flavor Substance Content Of Pleurotus Eryngii With Fermentable Corn Steep Liquor, Li Jing, Zheng Xi-Qun, Liu Xiao-Lan

Food and Machinery

Objective: In order to improve the comprehensive utilization value of corn steep liquor, fermentable corn steep liquor was used to partially replace bran for cultivation of Pleurotus eryngii. Methods: 6 percent of the nitrogen source in the traditional matrix was replaced by fermentable corn steep liquor in the cultivation of P. eryngii, and the differences in non-volatile flavor composition and nutritional value were analyzed by measuring the content and composition of free amino acids, organic acids, soluble glycol, 5'-nucleotides. Results: The results showed that the chemical scores of P. eryngii amino acids were 50.31 and 48.93, the BV values were …