Digital Commons Network^™

Global Impact Of Physical Inactivity And Implications For Public Health Nursing, Elizabeth A. Moxley, Kashica Webber-Ritchey, Laura Hayman

Faculty Articles, Papers, and Other Scholarship

Physical inactivity has been a public health problem worldwide for more than a decade. Of those who are physically active, a substantial percentage engage solely in low or very low physical activity (PA) levels. In the last 3 decades, the prevalence of PA in the United States has decreased with approximately 80% of adults not meeting the recommended guidelines for aerobic and muscle strengthening PA. The PA levels of youth have dramatically decreasedwith 85% of adolescents reporting no PA. Regular PA participation can aid in preventing chronic diseases. A strong inverse dose-response relationship exists between PA and the incidence of …

A Lesson Involving Nursing Management Of Diabetes Care: Incorporating Simulation In Didactic Instruction To Prepare Students For Entry-Level Practice, Elizabeth A. Moxley, Larry Maturin Jr., Desale Habtzghi

Faculty Articles, Papers, and Other Scholarship

Background: Diabetes is a global health problem requiring nursing students demonstrate a thorough understanding for NCLEX^® and entry-level practice, although clinical opportunities are increasingly limited, especially for Associate Degree Programs.

Method: A Simulation-based Education was incorporated in a didactic lesson to improve diabetes nursing care. Knowledge, confidence, application and relevance were measured using Wilcoxon signed-rank, Chi-square and Kruskal-Wallis analyses.

Results: Student (n=46, 85% female) perceived knowledge of glycemic management (post > pre, p < 0.0001), confidence administering insulin (post > pre, p < 0.0001), and clinical relevance improved. Confidence increased among three cohorts per Kruskal Wallis H test (² = 7.76, p = 0.021). Increased confidence correlated with relevance (² = 30.965, p = 0.009) and prior understanding of therapy ( …

Analyzing The Potential Of Bioelectrical Impedance Analysis In Identifying The Effects Of Freezing In Atlantic Sea Scallop Products (Placopecten Magellanicus), Joseph Ehrhard

All Theses And Dissertations

The sensitivity of bioelectrical impedance analysis (BIA) was investigated to assess the potential of identifying the effects of freezing in market-ready Atlantic sea scallops (Placopecten magellanicus). Measurements of resistance (R) and reactance (Xc) were recorded using a Certified Quality Reader (CQR) (Certified Quality Food Inc., Clinton Township, MI 48035) BIA device at 50kHz. Prior to investigating the effects of freezing on BIA measurements a standard operating procedure (SOP) was established to limit sources of error. BIA measurements were used in establishing an SOP which focused upon the preparation of samples through blot drying, as well as, proper orientation …

The Role Of Pim3 Kinase In Promoting Tumorigenesis, Tumor Metastasis, And Cancer Cell Stemness In Human Hepatoblastoma, Raoud Marayati

All ETDs from UAB

Hepatoblastoma is the most common primary liver tumor in children. Despite an increasing incidence and major advances in care for other pediatric solid tumors, therapy for hepatoblastoma has remained virtually unchanged for the last 20 years, and children with metastatic or relapsed disease continue to suffer from a dismal prognosis. Treatment strategies primarily rely on cisplatin, due to its role as the most active single agent in hepatoblastoma treatment. However, chemoresistance remains a significant challenge with 54-80% of patients developing resistance to chemotherapy after 4-5 cycles of treatment. We have previously demonstrated that Proviral Integration site in Maloney murine leukemia …

Association Between Antioxidant Capacity And Vascular Hemodynamics In Premenopausal Women Following 12 Weeks Of Exercise Training, Aparna Tamhane

All ETDs from UAB

Background: Oxidative stress induced by “free radicals” plays role in vascular dysfunction and cardiovascular health. Studies exploring beneficial effects of chronic aerobic training by enhancing antioxidant mechanisms in the body and thus, hemodynamic outcome measures are limited. Purpose: To assess effects of chronic aerobic exercise training on association between change (Δ) in antioxidant capacity, measured in terms of ferric reducing ability of plasma (ΔFRAP), and change in vascular hemodynamic (outcome) measures: systolic blood pressure (ΔSBP), diastolic blood pressure (ΔDBP), large arterial elasticity index (ΔLAEI) and small arterial elasticity index (ΔSAEI), in a cohort of healthy women. Methods: This was a …

Transcriptional Regulation And Islet Transplantation Advantages Of Brown Adipose Tissue, Jessica D. Kepple

All ETDs from UAB

Metabolic disease encompasses various disorders, including obesity and diabetes, that negatively impact glucose and lipid homeostasis and increase the risk of co-morbidities. Adipose tissue, which regulates whole-body energy balance and acts as a specialized endocrine tissue, is negatively affected by obesity and diabetes. Brown adipose tissue (BAT) functions to dissipate excess energy as heat and therefore is an attractive target against metabolic disease. To develop more effective therapeutic strategies, BAT physiology and genetic regulatory mechanisms need to be better understood. This dissertation highlights studies seeking to illuminate novel transcriptional regulation and islet transplantation applications of BAT. We investigated the requirement …

Effectiveness Of A University Employee Assistance Program Using The Workplace Outcome Suite And Client Satisfaction Survey, Josephine Jackson Banks

All ETDs from UAB

Background: Gallup (2013) reported that 30% of the U.S. workforce was not engaged in their work which means they were not reaching their full potential or productivity level. For organizations, lost productivity due to absenteeism or less than ideal performance at work impacts company performance and bottom line. Employee assistance programs are a resource to help increase employee health, productivity, and satisfaction through counseling interventions. Methods: Data were collected by a large urban university EAP over a 20-month period. The analysis was limited to EAP clients over the age of 18. A total of 866 subjects participated in this study, …

Socioeconomic Status In Adolescence And Dna Methylation In Young Adulthood, Malcolm Barker-Kamps

All ETDs from UAB

Children from low socioeconomic status (SES) families are at a greater risk of negative health outcomes in adulthood, in part from chronic stress. The chronic stress of these experiences may become biologically embedded through DNA methylation in stress-related genes. However, the effects of specific SES dimensions during childhood or adolescence on later epigenetic profiles in adulthood are not well understood. The present study examined the roles of two objective SES dimensions and two subjective SES dimensions experienced in early adolescence in DNA methylation in young adulthood. The analyses focused on two genes, NR3C1 and SLC6A4, because their methylation has been …

Importance Of The Zebrafish Model For Understanding Nutrition, Michael Britt Williams

All ETDs from UAB

The common zebrafish Danio rerio is a useful model for human health. Effective utilization of this model required development of husbandry and reproductive protocols as well as genomic sequencing and creation of relevant molecular techniques. However, the dietary needs of the species remain woefully under investigated. At this time no chemically-defined open source diets are available to the zebrafish research community. Consequently, those labs utilizing the zebrafish model rely on commercial diets that may not provide adequate nutrition and lack consistency needed for rigorous and reproducible research. The first focus of these studies was to examine the current state of …

Evidence For A Bioelectrical Marker Of Insulin Resistance In Premenopausal Women: Membrane Capacitance, Valene E Garr Barry

All ETDs from UAB

Insulin resistance (IR) is associated with poor metabolic and reproductive outcomes among premenopausal women. Early identification of women with IR might mitigate these outcomes. However, clinically suitable methods to identify women with IR are unavailable due to high cost, high patient burden, or limited reliability. The objective was to examine a bioimpedance-based approach to identifying women with IR using membrane capacitance (CM). CM is a measure of cell membrane health and function, which is independently associated with IR and may be a suitable predictor. We validated the association of CM with IR and established the clinical utility of CM as …

Predictors Of Subjective And Objective Everyday Functioning In Middle-Aged And Older Adults With Hiv, Alexandra Elaine Jacob

All ETDs from UAB

People with HIV (PWH) are at an increased risk for everyday functionalimpairment, especially as they age. The purpose of this study was: (1) to identify factors associated with subjective and objective instrumental activities of daily living (IADL) difficulty in PWH and (2) to identify factors associated with awareness of functional capacity. This cross-sectional study included 261 PWH. Participants completed a comprehensive neurobehavioral assessment, including self-report and performance-based measures of everyday functioning. Hierarchical multiple regressions were performed to identify health, psychological, and cognitive factors that contribute to subjective and objective evaluation of everyday functioning. We also examined factors that predicted a …

Rural And Urban Differences In Vegetable And Fruit Consumption Among Older Cancer Survivors In The Deep South: An Exploratory Cross-Sectional Study, Harleen Kaur

All ETDs from UAB

Background: Rural Americans have poorer overall health and physical functioning than their urban counterparts. A varied diet, rich in vegetable and fruit (V&F) consumption may improve health; however, little is known about rural-urban differences in V&F consumption, especially in older cancer survivors. Objective: To assess differences in V&F consumption among older cancer survivors residing in urban- and rural-designated areas, and explore whether differences exist by sex, race, and cancer type. Design: This was a cross-sectional secondary analysis. Participants/setting: Screening data from the Harvest for Health trial was obtained on 731 Medicare-eligible cancer survivors across Alabama. Main outcome measures: V&F consumption …

Chemical, Physical, And Antibacterial Properties Of Contemporary Pulp Capping Materials, Yu-Yin Lin

All ETDs from UAB

The purpose of this project was to compare the chemical, physical, and antibacterial properties of right contemporary direct pulp capping materials. The material categories included in this study were calcium hydroxide (Dycal, Lime-Lite and Ultra-Blend plus), calcium silicate (MTA Angelus, Biodentine, TheraCal LC), calcium aluminate (Ceramir Protect LC), and resin ionomer (Bio-Cap). Calcium release and pH changes were measured via a calcium ion-selective electrode (Vernier Company) and pH sensor (Vernier Company) respectively, after specimens were immersed in 36.8oC deionized water for 1, 7, 28 and 90 days. Water solubility was calculated with weight loss of the specimens from 0 to …

The Role Of Race, Sex, And Place In The Association Of Diabetes And Cardiovascular Disease, Gargya Malla

All ETDs from UAB

Cardiovascular disease risk is higher among adult with diabetes than those without diabetes. This increase in risk may vary by race, sex, and neighborhood characteristics. Recent US data showed a resurgence in stroke and coronary heart disease (CHD) among adults with diabetes, and an increase in heart failure (HF) mortality. Therefore, this dissertation investigated how cardiovascular disease risk may vary by race, sex, and neighborhood characteristics for adults across the glycemic spectrum.Data from the REasons for Geographic and Racial Differences in Stroke (REGARDS) study, an ongoing prospective cohort of 30,239 Black and White adults age 45 years at baseline (2003-07) …

Evaluation Of Antimicrobial Effect Of Licorice Extrcat Agiasnt Oral Microorganisms, Roshanak Rastegar

All ETDs from UAB

Introduction: The causative factors of dental caries have been studied for many years, however, preventing the formation of dental caries remains an elusive task. Microorganisms have been the focal point of numerous studies as a prime cariogenic factor. Streptococcus mutans and Candida albicans have been frequently co-isolated from dental biofilm in patients with early childhood caries (ECC) and studies have demonstrated the synergistic effects of these two microorganisms in promoting tooth demineralization. Acid and glucan production, which are two virulence factors produced by S. mutans that mediate biofilm formation and tooth decay, have been shown to be promoted during co-colonization …

An Investigation Into The Effects Of Diet On Pain And Pain Disparities, Larissa Jane Strath

All ETDs from UAB

Chronic pain is one of the most common and disabling disorders in Westernsociety. Recently, it has been suggested that dietary quality may play a key role in the development and maintenance of pain. Additionally, diet differs between demographic groups, as does physiological differences in response to metabolites. We sought to explore 1) the central way in which diet influences pain sensitivity and 2) if dietary patterns affected various demographic groups differently. We first employed a rat model to observe diet-related changes in the dorsal horn of the spinal cord. In the absence and presence of an injury, rats fed a …

From Deviance To Disease: How Congress Frames Opioid Use, 1994-2019, Stephanie Kirkland

All ETDs from UAB

Over the past thirty years, the use of opioids like heroin, fentanyl, oxycodone, and hydrocodone led to tens of thousands of deaths from overdoses and caused a public health crisis. Researchers have noted the roles of various social organizations and groups in creating a public discourse around this topic and have studied the changing public views of opioid use in light of new scientific research. And yet, there remains a gap in research on the role of the members of Congress in this public discourse. These legislators pass policies that directly affect people who live with or who know someone …

Using Authentic Online Resources In Russian For Stem Coursework For Novice Through Superior Level Learners, Molly Thomasy Blasing

Russian Language Journal

This article makes a case for incorporating STEM content into Russian language courses at the Novice through Superior levels of proficiency. The author presents models of asynchronous learning activities based on authentic online resources developed for a Russian for STEM pilot course taught during the COVID-19 pandemic. These lessons can be employed in online or face-to-face courses to prepare students to speak, read, write, and understand the language of STEM fields in Russian.

Dna Barcoding Approach To Characterize Microalgae Isolated From Freshwater Systems In Ecuador, Isabel Ballesteros, Paulina Terán, Cristina Guamán-Burneo, Nory González, Alejandra Cruz, Pablo Castillejo

Neotropical Biodiversity

The use of suitable DNA barcodes and the generation of databases with reference sequences have been considered a promissory approach for the identification of Chlorophyta and Cyanophyta microalgae. In this study, we carried out a molecular characterization and identification of strains isolated from freshwater systems in Ecuador using a dual barcode method. The target sequences for Chlorophyta were 18S rDNA and rbcL genes, and 16S rDNA and 16S–23S rDNA intergenic spacer (ITS) for Cyanophyta. We reported these DNA barcodes for 20 different Molecular Operational Taxonomic Units (MOTUs) for Chlorophyta and 10 for Cyanophyta. Our results show that the 18S V4 …

Lachryphagy By Cockroaches: Reptile Tears To Increase Reproductive Output?, Matthijs P. Van Den Burg, Javier Aznar González De Rueda

Neotropical Biodiversity

Lachryphagy, or tear-feeding, is generally considered as supplementary feeding by invertebrates with a long proboscis to acquire essential nutrients. Commonly reported vertebrate host species of lachrypaghic interations are humans and birds, and in reptiles concern large species: turtles and crocodiles, with one report from an iguanid host. Here, we report tear-feeding by a cockroach, a species lacking a proboscis, on a small squamate species, Anolis fuscoauratus. We address how the nutritional needs for the reproductive cycle may force cockroaches to explore any dietary source with essential nutrients. In addition to birds, our report adds Anolis as invertebrate predators that are …

The Structure Of Tardigrade Communities At Fine Spatial Scales In An Andean Polylepis Forest, Balbina P.L. Ramsay, Nigel J. Marley, David T. Bilton, Simon D. Rundle, Paul M. Ramsay

Neotropical Biodiversity

Little is known about distribution patterns of micrometazoan organisms at different spatial scales and the mechanisms driving these patterns across different environments. Here we explore the fine-scale structure of tardigrades in a high-elevation Polylepis forest in northern Ecuador. To investigate spatial patterns of tardigrade abundance, we collected samples from different bryophyte taxa (hosts) on the woodland floor. We identified some tardigrades to species, but most taxa were considered at the level of morphological operational taxonomic units. Tardigrade assemblages differed in composition between host taxa, with some tardigrade taxa associated more with certain hosts, which might relate to host architecture or …

Herbivory And Leaf Traits Of Two Tree Species From Different Successional Stages In A Tropical Dry Forest, Fernando Henrique De Sena, Bruno Melo Lustosa, Silvia Roberta Santos Silva, Hiram Marinho Falcão, Jarcilene Silva De Almeida

Neotropical Biodiversity

Leaf traits are analyzed as essential drivers for the evolutionary and ecological role of plant defense mechanisms. Plants show leaf trait variation as a response to the diverse environmental conditions, like different successional stages. Those variations can impact leaf herbivory rates and drive changes in the allocation of plant resources. In this study, we aimed at comparing the expression of leaf defenses in established plants over different successional stages in a tropical dry forest to understand how these defenses modify the plant–herbivore interactions based on herbivory rates. We analyzed physical leaf traits (specific leaf area, thickness, and density), nutrient content …

Sampling Performance Of Bait Traps In High Andean Fruit-Feeding Butterflies, Carlos Federico Álvarez, Alejandra Clavijo-Giraldo, Sandra Inés Uribe, Tomasz Wilhelm Pyrcz, Cristiano Agra Iserhard, André Victor Lucci Freitas, Mario Alejandro Marín

Neotropical Biodiversity

Studies on model organisms such as butterflies are useful tools for conservation decision-making. However, in tropical ecosystems with an intrinsic high diversity a full understanding of biotic communities is difficult to obtain. Bait trap samplings have traditionally been used for community appraisals related to ecological and conservation issues. Nonetheless, in the Andes Mountains, there is little knowledge related to the effectiveness of bait traps for butterfly sampling. In this study, we tested the success of fermented fruits and rotten fish baits for butterfly sampling in four land-cover types (páramo, cloud forests, mixed, and pasture) in the upper Rio Chico basin …

Developing And Evaluating A Quality Improvement Intervention To Facilitate Patient Navigation In The Accountable Health Communities Model, Jennifer L Holcomb, Gretchen H Walton, Itunu O Sokale, Gayla M Ferguson, Vanessa R Schick, Linda Highfield

Faculty, Staff and Student Publications

Introduction: The Accountable Health Communities (AHC) Model was designed to address the health-related social needs of Centers for Medicare & Medicaid Services beneficiaries. Bridge organizations across the AHC Model have identified lack of technical assistance and peer planning as potential barriers to Model success, particularly around patient navigation. The technical assistance and peer planning literature lacks an organizing, conceptual framework, but implementation science frameworks could serve as useful guides. The Strengthening Peer AHC Navigation (SPAN) research protocol seeks to fill this gap and will apply three implementation science frameworks, Consolidated Framework for Implementation Research, Intervention Mapping, and the Expert Recommendations …

Can The Circular Economy Concretize Sustainability? A Construal Level Approach To Encourage Sustainable Consumption., Jolie Gutentag

Theses and Dissertations

Despite a growing awareness and understanding of the impact our lifestyles have on the environment, most people have not adequately changed their consumption patterns. One possibility for the disconnect is the perceived abstractness of sustainability. Drawing on construal level theory, this research proposes that framing environmental sustainability as circularity, using the principles of the circular economy, reduces the perceived abstractness of sustainability. Four studies investigate the effects of circular framing on sustainable consumption behavior, including the moderating role of consumers’ chronic level of construal, an innate mindset reflecting a tendency to view information more concretely or abstractly. Findings provide initial …

Feasibility And Acceptability Of A Technology-Based, Rural Weight Management Int Ervention In Older Adults With Obesity, John A. Batsis, Curtis L. Petersen, Matthew M. Clark, Summer B. Cook, David Kotz, Tyler L. Gooding, Meredith N. Roderka, Rima I. Al-Nimer, Dawna M. Pidgeon, Ann Haedrich, K. C. Wright, Christina Aquila, Todd A. Mackenzie

Dartmouth Scholarship

Background

Older adults with obesity residing in rural areas have reduced access to weight management programs. We determined the feasibility, acceptability and preliminary outcomes of an integrated technology-based health promotion intervention in rural-living, older adults using remote monitoring and synchronous video-based technology.

Methods

A 6-month, non-randomized, non-blinded, single-arm study was conducted from October 2018 to May 2020 at a community-based aging center of adults aged ≥65 years with a body mass index (BMI) ≥30 kg/m2. Weekly dietitian visits focusing on behavior therapy and caloric restriction and twice-weekly physical therapist-led group strength, flexibility and balance training classes were delivered using video-conferencing …

Heeding The Call Of Covid-19, David Wiebers, Valery Feigin

Animal Sentience

We are grateful to all of our commentators. They have provided a wide range of valuable perspectives and insights from many fields, revealing a broad interest in the subject matter. Nearly all the commentaries have helped to affirm, refine, expand, amplify, deepen, interpret, elaborate, or apply the messages in the target article. Some have offered critiques and suggestions that help us address certain issues in greater detail, including several points concerning industrialized farming and the wildlife trade. Overall, there is great awareness and strong consensus among commentators that any solution for preventing future pandemics and other related health crises must …

Identifying Meaningful Dietary Intake And Physical Activity Questions For Individual And Population Health, Jennifer Bennett Shinall, David G. Schlundt, Et Al.

Vanderbilt Law School Faculty Publications

We aimed to identify valid screening questions for adults regarding physical activity and dietary behaviours that (a) were correlated with BMI, (b) were deemed by patients and providers to be relevant to clinical care, and (c) have utility for longitudinal understanding of health behaviours in populations. The goal was to identify screening questions that could be implemented at annual health care visits. First, we identified dietary behaviour questions and solicited patient input. Next, we tested both physical activity and dietary behaviour questions in a large sample to test their potential utility. Finally, we used cognitive interviews with patients and physicians …

Characterizing Industrial And Artisanal Fishing Vessel Catch Composition Using Environmental Dna And Satellite-Based Tracking Data, Demian A. Willette, Gabriela Navarrete-Forero, Zachary Gold, Apollo Marco D. Lizano, Leonardo Gonzalez-Smith, Giovanna Sotil

Biology Faculty Works

The decline in wild-caught fisheries paired with increasing global seafood demand is pushing the need for seafood sustainability to the forefront of national and regional priorities. Validation of species identity is a crucial early step, yet conventional monitoring and surveillance tools are limited in their effectiveness because they are extremely time-consuming and require expertise in fish identification. DNA barcoding methods are a versatile tool for the genetic monitoring of wildlife products; however, they are also limited by requiring individual tissue samples from target specimens which may not always be possible given the speed and scale of seafood operations. To circumvent …

Parental Substance Use And Its Impact On Children’S Health And Safety. Increased Need For Collaboration And Multidisciplinary Efforts, Blerta Shehaj, Joanne Chopak-Foss

Eagles Talking About the Public’s Health

No abstract provided.