Digital Commons Network^™

Predicting, Monitoring And Controlling The Growth Of Listeria In Complex Food Matrices, Laura Mary Nyhan

Theses

Listeria monocytogenes is a foodborne pathogen which is a significant challenge in food production, particularly for ready-to-eat (RTE) products. Incidence of Listeria in RTE foods can be reduced by the application of intelligent combinations of preservative factors or hurdles, while data quantifying the efficacy of hurdle combinations can be exploited and used in the area of predictive microbiology. Traditional culture-based techniques, such as viable plate counts, are commonly used to monitor the growth/survival of microorganisms in foods, however these methods are tedious, time-consuming and due to their destructive nature, are associated with low reproducibility and high variability. Therefore, rapid, non-invasive …

Predicting Carcass Cut Yields In Cattle From Digitalimages Using Artificial Intelligence, Darragh Matthews

Theses

Beef carcass classification in Europe is predicated on the EUROP grid for both fatness and conformation. Although this system performs well for grouping visually similar carcasses, it cannot be used to accurately predict meat yields from these groups, especially when considered on an individual cut level. Deep Learning (DL) has proven to be a successful tool for many image classification problems but has yet to be fully proven in a regression scenario using carcass images. Here we have trained DL models to predict carcass cut yields and compared predictions to more standard machine learning (ML) methods. Three approaches were undertaken …

Patient-Perceived Versus Actual Risk Of Cardiovascular Disease And Associated Willingness To Consider And Use Prevention Therapy, Ann Marie Navar, Tracy Y Wang, Shuang Li, Xiaojuan Mi, Zhuokai Li, Jennifer G Robinson, Salim S Virani, Eric D Peterson

Faculty, Staff and Students Publications

BACKGROUND: Cardiovascular prevention guidelines use estimated 10-year atherosclerotic cardiovascular disease (CVD) risk based on the pooled cohort equations to guide treatment decisions and engage patients in shared decision-making. We sought to determine patient perceived versus actual risk of atherosclerotic CVD and associations with willingness for preventive therapy.

METHODS: We evaluated calculated and perceived CVD risk among 4187 patients across 124 sites in the Patient and Provider Assessment of Lipid Management Registry. Ten-year risk was assessed using the pooled cohort equations; risk relative-to-peers was determined based on age-, sex-, and race-based percentiles; and patient estimates of risk were assessed using patient …

The Bile Acid Induced Hepatokine Orosomucoid Suppresses Adipocyte Differentiation, Sung Ho Lee, Jong Min Choi, Sung Yun Jung, Aaron R Cox, Sean M Hartig, David D Moore, Kang Ho Kim

Faculty, Staff and Students Publications

Bile acids have recently emerged as key metabolic hormones with beneficial impacts in multiple metabolic diseases. We previously discovered that hepatic bile acid overload distally modulates glucose and fatty acid metabolism in adipose tissues to exert anti-obesity effects. However, the detailed mechanisms that explain the salutary effects of serum bile acid elevation remain unclear. Here, proteomic profiling identified a new hepatokine, Orosomucoid (ORM) that governs liver-adipose tissue crosstalk. Hepatic ORMs were highly induced by both genetic and dietary bile acid overload. To address the direct metabolic effects of ORM, purified ORM proteins were administered during adipogenic differentiation of 3T3-L1 cells …

Effects Of Nutrition On Honey Bee Microbiology, Disease Occurrence, And Hive Growth, Shelby P. Fettig

EWU Masters Thesis Collection

Honey bees (Apis mellifera) are major pollinators of many food crops, but unfortunately, population declines are threatening global food security and ecosystem health. Honey bees are under multiple stressors, such as poor nutrition, parasitic mites, and pathogens. Similar to human health, the gut microbiome of the honey bee is hypothesized to affect bee’s overall health by supporting host metabolism and immune system. However, it’s not clear how stressors impact gut microbiome, and thus health, of bees. Nutritional supplementation could mitigate negative effects of stressors, particularly for bees that don’t have access to diverse floral resources. In this study, I conducted …

Conservative Clothing Effects On Body Composition Assessment By Air Displacement Plethysmography, Shaun L. Orvell, Kasuen Mauldin, John Gieng

Faculty Research, Scholarly, and Creative Activity

International Journal of Exercise Science 14(4): 687-695, 2021. Form-fitting spandex swimsuits or single-layer compression shorts are recommended during BOD POD® testing to ensure accurate results. The purpose of this study was to evaluate the effects of various outfit types on body composition measurements using the BOD POD®, and self-reported comfort level wearing each outfit. Twenty-one participants, 8 females and 13 males, (age 31.6 ± 9.8 years) wore a spandex swim cap and three different outfits during BOD POD® testing (manufacturer-recommended form-fitting spandex swimsuit, short sleeve spandex, long sleeve spandex). Measured variables include body mass, body fat percentage, body volume, and …

Mitochondrial Regulation Of Diabetic Kidney Disease, Daniel L Galvan, Koki Mise, Farhad R Danesh

Faculty, Staff and Students Publications

The role and nature of mitochondrial dysfunction in diabetic kidney disease (DKD) has been extensively studied. Yet, the molecular drivers of mitochondrial remodeling in DKD are poorly understood. Diabetic kidney cells exhibit a cascade of mitochondrial dysfunction ranging from changes in mitochondrial morphology to significant alterations in mitochondrial biogenesis, biosynthetic, bioenergetics and production of reactive oxygen species (ROS). How these changes individually or in aggregate contribute to progression of DKD remain to be fully elucidated. Nevertheless, because of the remarkable progress in our basic understanding of the role of mitochondrial biology and its dysfunction in DKD, there is great excitement …

The Key To Solving Agency Lock-In: Prepublication Regulatory Discussions (Pre Reg), Gwendolyn Savitz

Articles, Chapters in Books and Other Contributions to Scholarly Works

Most legally binding administrative rules emerge from the notice-and-comment process, which explicitly requires the agency to consider input from the general public. However, by the time the opportunity for public input occurs, the agency is already substantially locked into its chosen approach and cannot act on new information in the comments. This is true even though its chosen approach was decided upon with input from only those the agency routinely deals with. This process entrenches already established interests and prevents those without existing agency connections from meaningfully contributing earlier in the process.

This problem could be solved by holding public …

Nucleus Type-Specific Dna Methylomics Reveals Epigenetic “Memory” Of Prior Adaptation In Skeletal Muscle, Yuan Wen, Cory M. Dungan, C. Brooks Mobley, Taylor Valentino, Ferdinand Von Walden, Kevin A. Murach

Health, Human Performance and Recreation Faculty Publications and Presentations

Using a mouse model of conditional and inducible in vivo fluorescent myonuclear labeling (HSA-GFP), sorting purification of nuclei, low-input reduced representation bisulfite sequencing (RRBS), and a translatable and reversible model of exercise (progressive weighted wheel running, PoWeR), we provide the first nucleus type-specific epigenetic information on skeletal muscle adaptation and detraining. Adult (>4 mo) HSA-GFP mice performed PoWeR for 8 wk then detrained for 12 wk; age-matched untrained mice were used to control for the long duration of the study. Myonuclei and interstitial nuclei from plantaris muscles were isolated for RRBS. Relative to untrained, PoWeR caused similar myonuclear CpG …

Safety And Efficacy Of Fecal Microbiota Transplantation To Treat And Prevent Recurrent Clostridioides Difficile In Cancer Patients, Hiba Ali, Shruti Khurana, Weijie Ma, Yuanzun Peng, Zhi-Dong Jiang, Herbert Dupont, Hao Chi Zhang, Anusha S Thomas, Pablo Okhuysen, Yinghong Wang

Faculty, Staff and Students Publications

Background: Cancer patients are at increased risk of recurrent Clostridioides difficile infection (rCDI) due to malignancy itself, cancer therapy, and frequent antibiotic use and have a lower response rate to standard oral antibiotics. There are limited data on the safety and efficacy of fecal microbiota transplantation (FMT) for treating rCDI in cancer patients. We aim to describe our experience of using FMT to treat rCDI at a tertiary cancer center.

Methods: We conducted a retrospective study of cancer patients who underwent FMT for rCDI at The University of Texas MD Anderson Cancer Center from June 2017 through January 2020. Baseline …

An International Study Of Interobserver Variability Of “String Sign” Of Pancreatic Cysts Among Experienced Endosonographers, Seifeldin Hakim, Emmanuel Coronel, Graciela M Nogueras González, Philip S Ge, Suresh T Chari, Nirav Thosani, Srinivas Ramireddy, Ricardo Badillo, Tomas Davee, Marc F Catalano, Robert J Sealock, Sreeram Parupudi, Lyndon V Hernandez, Virendra Joshi, Atsushi Irisawa, Surinder Rana, Sundeep Lakhtakia, Peter Vilmann, Adrian Saftoiu, Siyu Sun, Marc Giovannini, Matthew H Katz, Michael P Kim, Manoop S Bhutani

Faculty, Staff and Students Publications

BACKGROUND AND OBJECTIVES: No single optimal test reliably determines the pancreatic cyst subtype. Following EUS-FNA, the "string sign" test can differentiate mucinous from nonmucinous cysts. However, the interobserver variability of string sign results has not been studied.

METHODS: An experienced endosonographer performed EUS-FNA of pancreatic cysts on different patients and was recorded on video performing the string sign test for each. The videos were shared internationally with 14 experienced endosonographers, with a survey for each video: "Is the string sign positive?" and "If the string sign is positive, what is the length of the formed string?" Also asked "What is …

Shu Altop News Issue #2, Spring, Dr. Susan L. Davis, Rn & Richard J. Henley College Of Nursing

News, Magazines and Reports

Updates from the Davis & Henley College of Nursing Sacred Heart University Alternatives to Opioids for Pain Grant.

Alternatives to Opioids for Pain (ALTOP) is a HRSA funded project to help combat the opioid epidemic in Connecticut.

"And They Took My Milk!", I. Bennett Capers

Faculty Scholarship

No abstract provided.

Physician Burnout: An Assessment Of Impact, Drivers And Design Of Prevention Programs, David Dupee

Yale Medicine Thesis Digital Library

Burnout merits close study, with particular attention paid to means of quantifying institutional impact, reducing provider burnout burden, and measuring said burden. This study utilized economic and qualitative analyses to indicate institutional impact. It modified and piloted an intervention for attending level physicians. It also proposes a novel wellness program for resident physicians based off of triumphs and gaps in literature. Lastly, it utilizes survey comparison to track overall changes in burnout rate at Yale New Haven Hospital (YNHH). Overall, the cost of physician burnout at YNHH was estimated to range between $171 and $233 million annually. Reducing physician burnout …

Stock Shows And Rodeos: The Crossroads Of Commodification, Consumption, And Care Of Nonhuman Animals, Erin Kidder

Electronic Theses and Dissertations, 2020-2023

This study explores the complex relationship between humans and nonhuman animals through the lens of stock shows and rodeos (SSR). This study employs a feminist theoretical framework and an interpretive qualitative research methodology to gain insight into the ways in which humans practice a range of speciesist behaviors relating to their commodification, consumption, and care of other animals. Data consist of semi-structured interviews with 21 individuals who participate in SSR as spectators and competitors and with two animal medical experts, along with field observations at three different SSR held in Florida and Texas. Findings suggest that nonhuman animals serve many …

Emotional Availability: A Practice-As-Research Exploration On Acting In Film And Theatre, Janice Munk

Electronic Theses and Dissertations, 2020-2023

Actors are frequently required to be emotionally available on the spot, in situations ranging from an early morning acting class, to filming a scene well past midnight after a full day on set. In theatre, there is the expectation to deliver the right emotion every performance, and in film, when the camera and crew are ready, the actor is expected to produce the emotion at that moment. This demand to give emotionally compelling performances can cause an actor to stress under the pressure to deliver. Acting for stage and film have similarities and differences, and an actor needs to learn …

Building Pastoral Capacity In The Post-Pandemic Era Alongside Of “Human Fraternity”, Greg Soetomo Sj

Asia Pacific Mission Studies

A great number of people have expressed their admiration for the document on “Human Fraternity for World Peace and Living Together” (HF). One of the comments that is commonly heard is, “We will use this document as a guide to build and strengthen good and vibrant interfaith and intercultural relations.” This desire for better relations is validated by a statement in the paper itself: “It is a document that invites all persons who have faith in God and faith in human fraternity to unite and work together so that it may serve as a guide for future generations to advance …

Identifying Biomarkers Of Alzheimer's Disease From The Dakhleh Oasis Kellis 2 Cemetery Using Icp-Ms, Emily Barron

Electronic Theses and Dissertations, 2020-2023

Alzheimer's disease is a prevalent disease that affects roughly 5.4 million individuals each year (Fisher et al., 2018). Understanding the prevalence of Alzheimer's disease within the bioarchaeological record can help anthropologists gain an understanding of a population's health while also understanding the potential social ramifications. Trace element analysis is a valuable tool that allows bioarchaeologists to gain insight into individuals' health and development within the context of the past. In bioarchaeological studies, hair analysis has been used to map the nutritional status and migration patterns of individuals of past peoples, with recent studies focusing on disease prevalence. Analysis of hair …

Using The Very Short Form Of The Children’S Behavior Questionnaire For Spanish-Speaking Populations In Low- And Middle-Income Countries: A Psychometric Analysis Of Dichotomized Variables, Elsa Lucia Escalante-Barrios, Sonia Suarez Enciso, Samuel P. Putnam, Helen Raikes, Sergi Fàbregues

Department of Child, Youth, and Family Studies: Faculty Publications

While the psychometric properties of the Spanish version of the Very Short Form of the Children’s Behavior Questionnaire (CBQ-VSF) have been assessed in the US and Europe in samples composed of middle- and high-income parents with high levels of education, no studies have tested the instrument in low-income Spanish-speaking populations living in low- and middle- income countries. To fill this gap, our cross-sectional study assessed the psychometric properties of the Spanish version of the CBQ-VSF version in a sample of 315 low-income and low-educated parents with preschool children living in the Caribbean Region of Colombia. While our findings revealed problems …

Food Program Participation Influences Nutrition Practices In Early Care And Education Settings, Bethany D. Williams, Susan B. Sisson, Irene Padasas, Dipti Dev

Department of Child, Youth, and Family Studies: Faculty Publications

Objective: To determine differences by Child and Adult Care Food Program (CACFP) participation on nutrition requirements and best practices and barriers to implementing both in early care and education programs (ECEs) stratified by context (centers vs home-based ECEs).

Design: Cross-sectional survey.

Setting: Three-thousand and fourteen licensed Nebraska ECEs in 2017.

Participants: One-thousand three hundred forty-five ECEs.

Main Outcome Measures: Director-reported nutrition practices in classrooms serving children aged 2-5 years (8 requirements for foods served, 5 best practices for foods served, and 14 best practices for mealtime behaviors).

Analysis: Chi-square analysis adjusted for multiple comparisons.

Results: Of the sample, 86.8% participated …

Improving Breastfeeding Environments And Feeding Practices In Family Child Care Homes With The Go Nap Sacc Program, Kara Kohel, Holly Hatton-Bowers, Natalie A. Williams, Dipti Dev, Donnia Behrends, Emily Hulse, Zainab Rida, Holly Dingman, Danae Dinkel, Liz Gebhart

Department of Child, Youth, and Family Studies: Faculty Publications

Purpose: Breastfeeding and responsive feeding are important practices that support the health of infants and women. In the United States, breastfeeding continuation rates remain lower than recommended, and working women face additional challenges with breastfeeding continuation. Providers in a family child care setting are uniquely positioned to support and provide important resources to families in their breastfeeding and infant feeding practices.

Methods: The Go NAP SACC program was designed to improve the nutrition and physical activity environments and practices in child care settings serving infants and young children. This evaluation focuses on Breastfeeding and Infant Feeding in Nebraska Family Child …

Supporting Children’S Healthy Development During Mealtime In Early Childhood Settings, Adrien D. Malek‑Lasater, Kyong‑Ah Kwon, Diane M. Horm, Susan B. Sisson, Dipti Dev, Sherri L. Castle

Department of Child, Youth, and Family Studies: Faculty Publications

The purpose of this study was to examine the frequency of and relationship between responsive feeding practices used during early childhood education (ECE) mealtimes and high-quality teaching practices and teacher characteristics. We found variation in teachers’ use of responsive feeding practices. Teachers were more often observed using role modeling than supporting eating self-regulation. Programs that implemented family style meal service had a generally higher use of responsive feeding practices. Overall, we found positive associations between high-quality teaching practices and responsive feeding practices. Teachers’ Head Start status was associated with teaching practices and role modeling during mealtime. Teachers’ education and salary …

Mealtime Emotional Climate And Child Health: A Systematic Review, Jasmin Smith, Jaclyn A. Saltzman, Dipti Dev

Department of Child, Youth, and Family Studies: Faculty Publications

Background: Positive mealtime emotional climate (MEC) has been linked to better nutrition, psychosocial, literacy and academic outcomes, and fewer behavior problems. However, MEC has been defined in a variety of ways across studies, limiting the ability to synthesize findings and plan future research.

Objective: To identify which child characteristics are associated with MEC and to determine how previous studies have measured MEC.

Methods: We searched three databases (1980–2020) for peer-reviewed articles measuring MEC. Inclusion criteria required at least one child-level outcome related to physical, nutritional, or developmental health; children aged 0–18 years old; and quantitative data using cohort, case-control, intervention, …

Improving Higher-Order Comprehension Skills Of Grade 3 Learners In A Second Language At A Quintile 2 School, In Cape Town, South Africa, Vuyokazi Fatyela, Janet Condy, Lawrence Meda, Heather Phillips

All Works

Background: Developing higher-order comprehension skills of learners in primary schools is a challenge that faces many countries. South Africa is no exception. Primary school learners in South Africa have particularly low literacy and comprehension skills: many learners struggle to read for understanding. There is little published scholarship that focuses on developing the comprehension skills of Grade 3 learners in a second language. A lack of practical classroom knowledge in this area is what this article seeks to address. Objectives: To improve the higher-order comprehension skills of Grade 3 learners in a second language. Method: A qualitative approach, using a case …

A Review Of The Efficacy Of The Dietary Intervention In Autism Spectrum Disorder, Zainab Taha, Khalid A. Abdalhai

All Works

BACKGROUND: Autism spectrum disorder (ASD) is an early-onset neurodevelopmental disorder with 1 in 68 children prevalence. The key symptoms of ASD include social deficits, verbal and non-verbal communication deficits, and restricted, repetitive patterns of behavior, interests, or activities. For unknown reasons, gastrointestinal symptoms are related to ASD. The aim of the current paper is to review the available literature on dietary interventions in children with ASD and provide up-to-date evidence. METHODS: Searches in online databases, using the search terms’ dietary intervention, “autism spectrum disorders,” and “autism” were conducted. The search targeted publications ranging from 2010 to 2020. RESULTS: Twenty-six studies …

Human Milk Microbiota And Oligosaccharides: A Glimpse Into Benefits, Diversity And Correlations, Carole Ayoub Moubareck

All Works

Human milk represents a cornerstone for growth and development of infants, with extensive array of benefits. In addition to exceptionally nutritive and bioactive components, human milk encompasses a complex community of signature bacteria that helps establish infant gut microbiota, contributes to maturation of infant immune system, and competitively interferes with pathogens. Among bioactive constituents of milk, human milk oligosaccharides (HMOs) are particularly significant. These are non-digestible carbohydrates forming the third largest solid component in human milk. Valuable effects of HMOs include shaping intestinal microbiota, imparting antimicrobial effects, developing intestinal barrier, and modulating immune response. Moreover, recent investigations suggest correlations between …

Chloroplast Immunity Illuminated, George R. Littlejohn, Susan Breen, Nicholas Smirnoff, Murray Grant

School of Biological and Marine Sciences

No abstract provided.

Recalibrating Directors’ Liabilities Amidst Technological Flux, Pey Woan Lee, Susanna Leong

Research Collection Yong Pung How School Of Law

In this chapter, we consider how to balance corporate innovation and personal liability in the specific context of directors’ exposure to personal liability for corporate copyright infringements. Directors may incur personal liability in the statutory context if they have ‘authorised’ the company’s infringement, or at common law if they acted as the company’s joint tortfeasor. Due to the conflicting policy goals of encouraging innovation whilst preserving personal accountability, we observe that this regime is unsatisfactory. Delving into the modern history of copyright law, we seek to demonstrate that directors of technological companies operate in an environment of high legal uncertainty …

P0082 / #337: Barriers To Delivering Enteral Nutrition In Picus: A Survey And New Quality Improvement Tool, L Tume, R Eveleens, S Verbruggen, G Harrison, Jm Latour, F Valla

School of Nursing and Midwifery

No abstract provided.

Subtly Encouraging More Deliberate Decisions: Using A Forcing Technique And Population Stereotype To Investigate Free Will, Alice Pailhès, Gustav Kuhn

School of Psychology

Magicians’ forcing techniques allow them to covertly influence spectators’ choices. We used a type of force (Position Force) to investigate whether explicitly informing people that they are making a decision results in more deliberate decisions. The magician placed four face-down cards on the table in a horizontal row, after which the spectator was asked to select a card by pushing it forward. According to magicians and position effects literature, people should be more likely to choose a card in the third position from their left, because it can be easily reached. We manipulated whether participants were reminded that they were …