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Transcriptome Profiling Of Stevia Rebaudiana Ms007 Revealed Genes Involved In Flower Development, Nurul Hidayah Samsulrizal, Khairul Shahyidi Khadzran, Tamil Sundram Meenakshi Sundram, Zarina Zainuddin, Siti Hajar Nor Shaarani, Nur Sabrina Ahmad Azmi, Sarahani Harun

Turkish Journal of Biology

Stevia rebaudiana is a medicinal plant recommended to diabetic or obese patients as an alternative sweetener owing to its low-calorie property. Previous studies have found that the stevioside level is highest at the time of flower bud formation and lowest at the time of preceding and following flower bud formation. Hence, this study aims to identify the genes involved in the flowering of local S. rebaudiana accession MS007 by investigating the transcriptomic data of two stages of growth, before flowering (BF) and after flowering (AF) that were deposited under accession number SRX6362785 and SRX6362784 at the NCBI SRA database. The …

Racism In Medicine And Science, Samantha Soriano

USF St. Petersburg campus Honors Program Theses (Undergraduate)

The history of racism and prejudice in the United States is not limited to segregation, slavery, and discrimination. Medical and scientific racism continue to disproportionately affect Black and Indigenous People of Color (BIPOC). BIPOC have been used for scientific advancement without full disclosure of potential harm or adequate compensation. Scientists and medical providers have dehumanized minority individuals by disrespecting their autonomy and targeting vulnerable populations. This thesis consists of a literature review that surrounds the history of medical and scientific exploitation of people of color, ethical guidelines surrounding research, eugenics, and how assumptions affect the quality of care that minority …

Physical And Behavioral Factors And Their Influence On Psychosocial Functioning And Adherence In Women With Celiac Disease, Joclyn R. Malys

PCOM Psychology Dissertations

Celiac disease is a chronic autoimmune disease with physiological symptoms including diarrhea, vomiting, abdominal pain, and anemia. Weight change before and after treatment is common among women with Celiac disease. The relationship between the physical manifestations of Celiac disease and their effects on psychosocial functioning is unclear. The purpose of this study was to examine the effects of the magnitude of weight change on depression, body image, and eating behaviors. This cross-sectional study used data that were collected via online anonymous surveys from 140 women with Celiac disease. Functioning and adherence were assessed using the Patient Health Questionnaire-9 (PHQ-9), The …

Neuropathy In Covid-19 Associated With Dysbiosis-Related Inflammation, Busra Aktas, Belma Aslim

Turkish Journal of Biology

Although COVID-19 affects mainly lungs with a hyperactive and imbalanced immune response, gastrointestinal and neurological symptoms such as diarrhea and neuropathic pains have been described as well in patients with COVID-19. Studies indicate that gut-lung axis maintains host homeostasis and disease development with the association of immune system, and gut microbiota is involved in the COVID-19 severity in patients with extrapulmonary conditions. Gut microbiota dysbiosis impairs the gut permeability resulting in translocation of gut microbes and their metabolites into the circulatory system and induce systemic inflammation which, in turn, can affect distal organs such as the brain. Moreover, gut microbiota …

Targeting Cov-2 Spike Rbd And Ace-2 Interaction With Flavonoids Of Anatolian Propolis By In Silico And In Vitro Studies In Terms Of Possible Covid-19 Therapeutics, Hali̇l İbrahi̇m Güler, Fulya Ay Şal, Zehra Can, Yakup Kara, Oktay Yildiz, Ali̇ Osman Beldüz, Sabri̇ye Çanakçi, Sevgi̇ Kolayli

Turkish Journal of Biology

Propolis is a multi-functional bee product rich in polyphenols. In this study, the inhibitory effect of Anatolian propolis against SARS-coronavirus-2 (SARS-CoV-2) was investigated in vitro and in silico. Raw and commercial propolis samples were used, and both samples were found to be rich in caffeic acid, p-coumaric acid, ferulic acid, t-cinnamic acid, hesperetin, chrysin, pinocembrin, and caffeic acid phenethyl ester (CAPE) at HPLC-UV analysis. Ethanolic propolis extracts (EPE) were used in the ELISA screening test against the spike S1 protein (SARS-CoV-2): ACE-2 interaction for in vitro study. The binding energy values of these polyphenols to the SARS-CoV-2 spike and ACE-2 …

Treatment Of Covid-19 Patients With Quercetin In Combination With Vitamin C And Bromelain: A Prospective, Single - Centre, Randomized, Controlled Trial, Hasan Önal, Bengü Arslan, Nurcan Üçüncü Ergun, Hani̇m Şeyma Topuz, Seda Yilmaz Semerci̇, Mehmet Eren Kurnaz, Yulet Mi̇ray Molu, Mehmet Abdussamet Bozkurt, Nuretti̇n Süner, Ali̇ Kocataş

Turkish Journal of Biology

Scientific research continues on new preventive and therapeutic strategies against severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2). So far, there is no proven curative treatment, and a valid alternative therapeutic approach needs to be developed. This study is designed to evaluate the effect of quercetin in COVID-19 treatment. This was a single-centre, prospective randomized controlled cohort study. Routine care versus QCB (quercetin, vitamin C, bromelain) supplementation was compared between 429 patients with at least one chronic disease and moderate-to-severe respiratory symptoms. Demographic features, signs, laboratory results and drug administration data of patients were recorded. The endpoint was that QCB supplementation was …

Determination Of The Interaction Between The Receptor Binding Domain Of 2019-Ncov Spike Protein, Tmprss2, Cathepsin B And Cathepsin L And Glycosidic And Aglycon Forms Of Some Flavonols, Erman Sali̇h İsti̇fli̇, Arzuhan Şihoğlu Tepe, Paulo Augusto Netz, Cengi̇z Sarikürkcü, İbrahi̇m Hali̇l Kiliç, Bektaş Tepe

Turkish Journal of Biology

The novel coronavirus (COVID-19, SARS-CoV-2) is a rapidly spreading disease with a high mortality. In this research, the interactions between specific flavonols and the 2019-nCoV receptor binding domain (RBD), transmembrane protease, serine 2 (TMPRSS2), and cathepsins (CatB and CatL) were analyzed. According to the relative binding capacity index (RBCI) calculated based on the free energy of binding and calculated inhibition constants, it was determined that robinin (ROB) and gossypetin (GOS) were the most effective flavonols on all targets. While the binding free energy of ROB with the spike glycoprotein RBD, TMPRSS2, CatB, and CatL were -5.02, -7.57, -10.10, and -6.11 …

Association Between Prepregnancy Obesity And Health Behaviors, Adverse Conditions, And Birth Outcomes In South Dakota, Lily Sanderson

Electronic Theses and Dissertations

Introduction: Prepregnancy obesity is associated with an increased risk for various adverse outcomes for mother and fetus. These adverse associations exist within the realms of preconception health, prenatal health, birth outcomes, and postnatal health.
Methods: This retrospective cohort study used data from the South Dakota Pregnancy Risk Assessment Monitoring System (SD PRAMS) survey, which is an ongoing statebased surveillance system of maternal behaviors, attitudes, and experiences before, during, and shortly after pregnancy. The 2017 and 2018 SD PRAMS sampled a total of 3,805 mothers who were randomly selected from birth certificate records to be representative of all South Dakota women …

Exploring The Relationship Between Antenatal Care And Postnatal Care To Newborn Outcomes In Borno State, Northeastern Nigeria, Adebe Gabriel

Walden Dissertations and Doctoral Studies

Newborn outcomes (morbidity or mortality) have been on the increase in Borno State. This study explores the relationship between antenatal care (ANC) and postnatal care (PNC) and newborn outcomes among women in Mafa local government area, Borno State. Also examined were the relationships between transportation and newborn outcomes, women’s knowledge of illness during pregnancy and ANC attendance, availability of staff/health workers, availability of supplies/equipment relations with ANC and PNC attendance. The three delays model was used as theoretical framework. The research will be useful for government and program-implementing partners to guide quality reproductive maternal newborn child adolescent health and nutrition …

Resilience As A Moderator Between Food And Housing Insecurity And Mental Distress, Denise Mchugh Loggie

Walden Dissertations and Doctoral Studies

The prevalence of food insecurity (FI) and housing insecurity (HI) in college students has increased over the last decade along with an associated increase in mental health problems. Studies show significant increases in many markers for mental distress in this population including a higher prevalence of mood disorders, non-lethal self-harm, and attempted and completed suicides, particularly over the last decade. Compounding these challenges is the low level of resilience found in college-age young adults, potentially limiting their ability to cope with and recover from the hardship of FI and HI. This quantitative study, guided by resilience theory and Maslow’s hierarchy …

How Women Who Have Recidivated Describe Their Readiness For Employment After Release From Prison, Simba Kathleen Fox

Walden Dissertations and Doctoral Studies

Since the 1980s, the population of women prisoners incarcerated in the state of California had significantly increased by 500% more than that of the male prisoners. The United States had more incarcerated women than any other country. Along with this alarming rise in female incarceration, recidivism rates were also higher among female inmates. This problem has negatively affected women in California; whereas 57% of the women released from prison were rearrested within three to seven years. The purpose of this qualitative phenomenological research study was to investigate how 18 women who had recidivated with the same or a different criminal …

Breastfeeding Information And Breastfeeding Duration Among African American Women With A Family History Of Breast Or Ovarian Cancer, Aleatha Johnson

Walden Dissertations and Doctoral Studies

Decades of research supports the notion that breastfeeding may help prevent breast and ovarian cancer in women. Women with a family history of these cancers are at greater risk. African American women have the lowest breastfeeding rates, yet the highest breast and ovarian cancer mortality rates. No studies have been conducted exploring the impact of being informed about breastfeeding from health care providers, breastfeeding support services, or family and friends and the relationship between their knowledge of family history of breast or ovarian cancer and breastfeeding duration for African American women. The purpose of this quantitative study was to determine …

Lived Experiences Of Parents Regarding Their Elementary-Age Child’S Exclusion From School Due To Behavioral Problems, Lauren Claire Ferber

Walden Dissertations and Doctoral Studies

AbstractDisciplinary exclusion, particularly school expulsion, presents a significant challenge to school-age children and their families. Although the impacts of disciplinary exclusion from school on children are well-known, less is known about how this phenomenon affects their parents. The purpose of this qualitative phenomenological study was to understand the lived experiences of parents who have a child who has been subjected to disciplinary exclusion due to behavioral problems in the classroom. Bronfenbrenner’s ecological systems theory provided the framework for this study. Data were collected from semistructured interviews with 12 parents of children who faced exclusion. Four themes emerged from coding analysis: …

The Importance Of Understanding Functionality In Home- And Community-Based Care And The Impact On Costs As America Ages, Shannon Stanley

Walden Dissertations and Doctoral Studies

The United States is on a trajectory to reach 20% of citizens aged 65 and over by 2030. This hyper-aging population affects the costs of healthcare, but it is not adequately represented in current U.S. models. Studies indicate other hyper-aged nations have experienced this increase and implemented long-term care measures to counter the increase in aging populations and costs with system responsiveness. This study examined the role of Medicaid home -and community- based service (HCBS) contributions in states that have the fastest-aging populations. Using the established framework and data collected by the Centers for Medicare and Medicaid, the study looked …

Parents’ Decision Making And Uptake Of Human Papillomavirus Vaccination Among Adolescent Males, Franklyn Penn

Walden Dissertations and Doctoral Studies

Human papillomavirus (HPV) infections account for most oropharyngeal, anal, and penile cancers among men. Two vaccines have been recommended for boys 11 years of age or older to prevent HPV infection, but HPV vaccination rates are far below the Healthy People 2030 target goal. Some research indicates the role of the parent is vital in HPV vaccine uptake, but to what extent is unclear. Through quantitative secondary data analysis of the National Immunization Survey-Teen 2016 (NIS-Teen) data set (n = 43,271) that was grounded in the health belief model, chi-square, and logistic regression analyses revealed three key findings. First, male …

Perceptions Of Using Complementary Alternative Medicine During Pregnancy For Nausea And Vomiting, Debra L. Blackett

Walden Dissertations and Doctoral Studies

Nausea Vomiting during Pregnancy (NVP) conditions have commonly occurred among pregnant women during gestation for more than 4,000 years. The purpose of the multicase qualitative design was to examine and improve the understanding of perceptions of pregnant women experiencing nausea and the potential use of Complementary Alternative Medicine (CAM) modalities to treat NVP symptoms. In this study, the Health Belief Model six core constructs provided the foundation for the theoretical framework for the process, explaining how working pregnant women experience decision-making and relate to the daily challenges associated with pregnancy. The research questions examined experience of coping with NVP and …

Effect Of Vegan Diet On Cardiovascular Health, Rachel Schottenfeld

Capstone Showcase

Abstract

Introduction: Cardiovascular disease (CVD) is the leading cause of death globally, and in the United States, regardless of socioeconomic strata. Current diet guidelines in the US endorse the consumption of animal products, but research show retrospective, prospective and cross-sectional studies that a vegan diet is more effective at reducing BP, cholesterol, blood sugar levels, and body mass index (BMI) as compared to a non-vegan diet. This paper will focus on the benefits of a vegan diet (I) in reducing CVD risk (O) in adults (P) as compared to a non-vegan diet (C). It is the hope that increased focus …

Effect Of Probiotics Supplementation In The Treatment Of Parkinson’S Disease, Sophia Tse

Capstone Showcase

Parkinson’s Disease (PD) is a neurodegenerative disease that results from the depletion of dopamine-secreting nerve cells. The mainstay of treatment for PD is Levodopa, a precursor to dopamine, which helps replenish dopamine levels in the body. However, this treatment is not curative and does not delay disease progression. PD, as an alpha-synucleinopathy, is hypothesized to have a potential pathway of disease development and progression through the brain-gut axis. This literature review investigated the effect of probiotics supplementation in the treatment of PD. Although the analysis of six articles demonstrated only one study with definitive benefits of probiotics supplementation in PD, …

Restoration Through Regeneration: An Analysis Of Agriculture In The United States, Rebecca Norine Graham

Capstone Showcase

The industrialization of agriculture in the mid-twentieth century has revolutionized global food systems, with enough food produced annually to sustain 10 billion people on a planet of only 7.8 billion people. Such a high-yielding agricultural system comes at a great cost to the Earth’s ecosystem, as industrialized farming has taken on factory-like production methods. Particularly harmful is the livestock sector, with ruminating animals such as cattle contributing to rising global temperatures and environmental degradation. The environmental destruction caused by industrialized animal agriculture can be halted and ultimately reversed through regenerative agriculture. Regenerative agriculture is a restorative farming practice that promotes …

Experiential Learning In Soil Science: Evaluating Soil Quality In South Wollo, Ethiopia, Melissa Allen, Martha Mamo, Shimelis Beyene, Teshome Regassa, Gandura O. Abagandura, Solomon Abreha, Anthony James Mucia, Tsegaye Tadesse

National Drought Mitigation Center: Faculty Publications

This study abroad program provided an opportunity to enhance the international experience and research skills of University of Nebraska-Lincoln (UNL) students within a multidisciplinary team’s research-education goal on improving food security in Ethiopia. The experiential study component of the project included preparatory sessions during the Fall 2015 Semester at the UNL followed by a four- to five-week fieldwork experience in Ethiopia. Teams from the UNL and an Ethiopian university participated in survey data collection and field soil evaluations from farms in the Gerado area of South Wollo, Ethiopia. Having students interact with farmers increased student self-confidence and enhanced their leadership …

Meta-Techniques For Faculty Development: A Continuous Improvement Model For Building Capacity To Facilitate In A Large Interprofessional Program, S. A. Williams, Amy D. Johnson, L. B. Cross

ETSU Faculty Works

Literature regarding faculty development in uniprofessional healthcare programs is prolific; however, little has been written about instructional programs designed for faculty delivering interprofessional education (IPE). In this paper, we describe the genesis, content, and improvement of a faculty development workshop which exemplifies a meta teaching model and was designed to serve faculty facilitators in a rapidly growing IPE program. Evaluations following initial delivery of the workshops in fall 2018 returned high faculty satisfaction ratings and feedback suggesting a need for even more pedagogical training with a stronger emphasis on meta techniques and less on a review of student content. In …

The State Of Woodford County’S Assistance Network, Katherine Connair

MPA/MPP/MPFM Capstone Projects

This study seeks to determine what the overall picture of assistance network serving the Woodford County region is. The goal was to determine if there are any observable gaps in the network and to have a clear understanding of what the assistance network is. Gaps were identified by studying the existing network, surveying network members, and examining publicly available resources. A Strengths, Weaknesses, Opportunities, and Threats (SWOT) analysis was conducted to analysis the whole network. Assistance for this study refers to programs/organizations that provide cash or in-kind benefits/services to people (U.S. Census Bureau). The assistance network is all of the …

Horn Fly (Diptera: Muscidae) - Biology, Management, And Future Research Directions, Gary Brewer, Dave J. Boxler, Luisa D. Domingues, Rebecca T. Trout Fryxell, Chris Holderman, Kelly M. Loftin, Erika Machtinger, Brandon Smythe, Justin L. Talley, Wes Watson

Department of Entomology: Faculty Publications

The horn fly, Haematobia irritans irritans (L.), is one of the most important external parasites of cattle in North America and elsewhere. Horn fly adults have an intimate association with cattle, their primary host. With their often-high numbers and by feeding up to 38 times per day per fly, horn flies stress cattle. The resulting productivity loss is valued at more than 2.3 billion USD in the United States. Insecticides are commonly used to mitigate direct injury from feeding and indirect injury from disease transmission. This paper discusses horn fly biology, distribution, and management. Emphasis is on promising new approaches …

Cost Of Co-Infection In Peromyscus Leucopus Mice, Ananya Sagar

Scripps Senior Theses

Abstract

Co-infections occur frequently across humans & wildlife, and can have effects on host health. Despite the prevalence of microparasite-helminth co-infections, majority of the research focuses either on singular infections or on concurrent infections in a laboratory setting. This fails to take into account the interspecific interactions between the multiple parasites and the host in natural settings. The interactions could be direct by resource competition, or indirect via the host immune system. In our research, we studied the relationship between nematodes and coccidia in their host, Peromyscus leucopus mice, at the Mountain Lake Biological Station, Virginia. We further evaluated the …

Reducing Weight Bias: Creating An Anti-Weight Stigma Educational Simulation For Nurse Practitioner Students, Andrea A. Eickelmann

Doctor of Nursing Practice Projects

Background: Large-bodied people make up the majority of the American population, but healthcare providers are rarely taught specific techniques and strategies for management of their care and medical spaces are designed with furniture and equipment that does not accommodate large bodies. This alienation has resulted in a measurable detriment to the population’s mortality and morbidity, such increased mortality of 60% from experiencing weight stigma and over 50% high combined cancer death rates as compared to the rates of those with normal BMIs (Sutinet al., 2015; Calle et al., 2003).

Objective: This project will examine the evidence about weight stigma, efficacy …

Aboveground Herbivory Influences Belowground Defense Responses In Maize, Lise Pingault, Saumik Basu, Prince Zogli, W. Paul Williams, Nathan Palmer, Gautam Sarath, Joe Louis

Department of Entomology: Faculty Publications

The European corn borer (ECB; Ostrinia nubilalis) is an economically damaging insect pest of maize (Zea mays L.), an important cereal crop widely grown globally. Among inbred lines, the maize genotype Mp708 has shown resistance to diverse herbivorous insects, although several aspects of the defense mechanisms of Mp708 plants are yet to be explored. Here, the changes in root physiology arising from short-term feeding by ECB on the shoot tissues of Mp708 plants was evaluated directly using transcriptomics, and indirectly by monitoring changes in growth of western corn rootworm (WCR; Diabrotica virgifera virgifera) larvae. Mp708 defense responses …

Caregiver Knowledge And Perceptions Of Dementia-Specific Nutritional Approaches, Danielle Freitag

All Graduate Theses, Dissertations, and Other Capstone Projects

Dementia is a syndrome that affects millions worldwide. The syndrome can cause great distress not only for the diagnosed individual but also for the family and friends who provide care. It is known that many caregivers for people with dementia face difficulties in planning and preparing meals, feeding, and making nutritional decisions for their loved ones. Several diets have been shown to assist with dementia-related symptoms pre and post diagnosis. However, what is unknown is whether caregivers are aware of the benefits of these diets and what the barriers are to implementing them into their nutrition regime. This study surveyed …

Safety And Efficacy Of Bioidentical Hormone Therapy In Menopause: A Literature Review, Kathryn Akre

All Graduate Theses, Dissertations, and Other Capstone Projects

Vasomotor symptoms (VMS) experienced during menopause can negatively impact a woman’s quality of life, productivity, sleep, and mood. Systemic hormone therapy (HT) is the most effective treatment for moderate to severe VMS, however safety concerns raised by the 2002 Women’s Health Initiative (WHI) trial have led to a decrease in overall HT use and a growing demand for custom-compounded bioidentical HT. Misconceptions regarding the superior safety and efficacy of custom-compounded hormones and lack of clinician expertise in menopause management contribute to ongoing uncertainty and low uptake of United States (U.S.) Food and Drug Administration (FDA) approved bioidentical HT products. This …

Reducing Disease Exacerbation In Women With Confirmed Copd: A Systematic Literature Review, Jill Essay

All Graduate Theses, Dissertations, and Other Capstone Projects

Abstract

A systematic literature review was conducted to establish whether gender specific treatment exists for patients with Chronic Obstructive Pulmonary Disease (COPD), specifically, women with (COPD). The PICO question developed for this review is as follows: In women with confirmed diagnoses of COPD, does gender-specific treatment, compared to standard treatment, impact the frequency of exacerbations? Could the number of COPD exacerbations in women be reduced by incorporating interventions designed with (female) gender in mind? Four databases were included in the search: CINAHL, Pubmed, Medline, and Nursing and Allied Health. Articles included addressed gender differences in relation to the disease process, …

The Impact Of A Plant-Based Diet On The Prevention And Management Of Type 2 Diabetes Mellitus, Megan E. Ziola

All Graduate Theses, Dissertations, and Other Capstone Projects

Background: In the United States, type 2 diabetes is on the rise. Through lifestyle modifications, adults can prevent, delay, or help manage diabetes. Consuming a plant-based diet means limiting or eliminating animal products while focusing on fruits, vegetables, and whole grains. This dietary habit may be beneficial when it comes to diabetes prevention and treatment.

Objectives: A literature review was conducted to determine the effects of a plant-based diet on the prevention and treatment of type 2 diabetes in adults.

Methods: The search process was limited to 2010-2020. The databases including Academic Search Premier, CINAHL, Cochrane Database of Systematic Reviews, …