Digital Commons Network^™

Chromosome Xq23 Is Associated With Lower Atherogenic Lipid Concentrations And Favorable Cardiometabolic Indices, Pradeep Natarajan, Akhil Pampana, Sarah E. Graham, Sanni E. Ruotsalainen, James A. Perry, Paul S. De Vries, Jai G. Broome, James P. Pirruccello, Michael C. Honigberg, Krishna Aragam, Brooke Wolford, Jennifer A. Brody, Lucinda Antonacci-Fulton, Moscati Arden, Stella Aslibekyan, Themistocles L. Assimes, Christie M. Ballantyne, Lawrence F. Bielak, Joshua C. Bis, Brian E. Cade, Donna K. Arnett

Epidemiology and Environmental Health Faculty Publications

Autosomal genetic analyses of blood lipids have yielded key insights for coronary heart disease (CHD). However, X chromosome genetic variation is understudied for blood lipids in large sample sizes. We now analyze genetic and blood lipid data in a high-coverage whole X chromosome sequencing study of 65,322 multi-ancestry participants and perform replication among 456,893 European participants. Common alleles on chromosome Xq23 are strongly associated with reduced total cholesterol, LDL cholesterol, and triglycerides (min P = 8.5 × 10⁻⁷²), with similar effects for males and females. Chromosome Xq23 lipid-lowering alleles are associated with reduced odds for CHD among 42,545 …

Benefits Of Montessori Method Use In Activity Involvement On Individuals With Dementia, Megan Canzoneri

MOT Student Capstones

Background: The Montessori Method was a teaching approach developed by Dr. Maria Montessori for children who did not have access to proper education and materials. She used this method by teaching them through familiar tasks, puzzles, and self-driven interest. This taught them independence, problem-solving, and decision make. This project discusses the use of the method within the geriatric and memory care population to help them remain independent through choosing activities that interest them. These activities consist of familiar tasks such as setting a table, washing dishes, and folding clothes. Method: This project used a needs survey, pre- and post-survey, and …

Expressive Arts In Occupational Therapy: Children Traumatized From Opioid-Addicted Caregivers, Laura Maclean

MOT Student Capstones

Occupational therapy has been associated with expressive arts and the act of healing the body and mind since the inception of the profession. Children use expressive arts to self-express, explore, and enhance the development of the brain and body. Children that have experienced trauma may have trouble recognizing and expressing emotions, thus react with negative behaviors, poor social skills, and learning challenges. Trauma may occur in children from caregivers' behaviors due to opioid addiction. The use of expressive arts through occupational therapy's holistic perspective provides traumatized children with a guide to recognize and express emotions, increase attention, and improve social …

Learn About The Best Varieties Of Seedless Table Grapes To Grow In Nh, Lori Tyler Gula

UNH Today Archive

No abstract provided.

The Utah Statesman, April 12th, 2021, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Effects Of Socioeconomic Status On Glycemic Control In Children And Young Adults With Type 1 Diabetes, Julianna Morgan

Undergraduate Research and Scholarship Symposium

The purpose of this research presentation is to identify the relationship between socioeconomic status and glycemic control in children and young adults living with Type 1 diabetes. Poor blood glucose regulation can often lead to various lasting complications such as chronic kidney disease, loss of eyesight, infection, and even death. These can be devastating to an individual, yet preventable. The complications resulting from the lack of strict glucose regulation are a significant problem currently facing healthcare and disproportionally affecting patients from lower socioeconomic groups. Using CINAHL, research studies about the relationship between type 1 diabetes control and socioeconomic status were …

Functional Interpretation Of Atad3a Variants In Neuro-Mitochondrial Phenotypes, Zheng Yie Yap, Yo Han Park, Saskia B Wortmann, Adam C Gunning, Shlomit Ezer, Sukyeong Lee, Lita Duraine, Ekkehard Wilichowski, Kate Wilson, Johannes A Mayr, Matias Wagner, Hong Li, Usha Kini, Emily Davis Black, Kristin G Monaghan, James R Lupski, Sian Ellard, Dominik S Westphal, Tamar Harel, Wan Hee Yoon

Faculty, Staff and Students Publications

BACKGROUND: ATPase family AAA-domain containing protein 3A (ATAD3A) is a nuclear-encoded mitochondrial membrane-anchored protein involved in diverse processes including mitochondrial dynamics, mitochondrial DNA organization, and cholesterol metabolism. Biallelic deletions (null), recessive missense variants (hypomorph), and heterozygous missense variants or duplications (antimorph) in ATAD3A lead to neurological syndromes in humans.

METHODS: To expand the mutational spectrum of ATAD3A variants and to provide functional interpretation of missense alleles in trans to deletion alleles, we performed exome sequencing for identification of single nucleotide variants (SNVs) and copy number variants (CNVs) in ATAD3A in individuals with neurological and mitochondrial phenotypes. A Drosophila Atad3a Gal4 …

Effect Of Preoperative Versus Postoperative Use Of Transversus Abdominis Plane Block With Plain 0.25% Bupivacaine On Postoperative Opioid Use: A Retrospective Study, Richard Kalu, Peter Boateng, Lauren Carrier, Jaime Garzon, Amy Tang, Craig Reickert, Amalia Stefanou

Surgery Articles

BACKGROUND: Enhanced recovery protocols optimize pain control via multimodal approaches that include transversus abdominis plane (TAP) block. The aim of this study was to evaluate the effect of preoperative vs. postoperative plain 0.25 % bupivacaine TAP block on postoperative opioid use after colorectal surgery.

METHODS: A retrospective cohort study comparing postoperative opioid use in patients who received preoperative (n = 240) vs. postoperative (n = 22) plain 0.25 % bupivacaine TAP blocks. The study was conducted in a single tertiary care institution and included patients who underwent colorectal resections between August 2018 and January 2020. The primary outcome of the …

Indoor Vertical Farming Potential Solution To Long-Term Global Food Security Issues, Natalie Rigby

Student Research Symposium

Indoor vertical farming may be a solution for global food security issues, especially those driven by climate change, supply chain disruptions, environmental decline, and urban sprawl. This method of cultivation has numerous benefits and drawbacks dependent on the different options used. This presentation will use resilience frameworks developed by USU's Center for Anticipatory Intelligence to help identify these threats facing global food systems and how they may be mitigated by indoor vertical farms. In the coming years, rapid climate change issues are predicted to play an important role in agriculture around the world. The world currently faces a number of …

Physicochemical Properties Of High Protein Rice Flours And Application In A Cupcake, Ricardo Jose Santos Aleman

LSU Master's Theses

Rice (Oryza sativa L.) is an important ingredient for the development of gluten free bakery products. The quality of these types of products varies depending on the levels of rice amylose, particle size of the rice flour, grain length, water absorption rate and the used of other ingredients such as hydrocoillds. This research work aimed to develop a cupcake using high protein brown rice flour in combination with tapioca starch and potato starch of which the formulations were evaluated for textural properties (resilience, springiness, chewiness, cohesiveness and hardness), specific volume, color and sensory attributes, using a mixture design of Simplex-Centroid …

The Influence Of A Mindfulness-Based Curriculum On Executive Function In Four-Year-Olds, Victoria Mccann

Honors Theses

Research on the effectiveness of mindfulness as a method for improving a variety of psychological, social, and emotional skills has grown throughout the last decade. Extensive literature reviews show promising results for the improvement of executive function skills utilizing mindfulness-based interventions, though the current literature is primarily focused on adults, adolescents, and older children. Preliminary work has suggested that training executive function skills using mindfulness-based interventions in early childhood would be beneficial, but few studies investigating mindfulness-based interventions for young children exist. The purpose of this study was to examine whether a 12-week mindfulness-based curriculum using yoga had an impact …

Mitochondria Delay Proteolysis In An In Vitro Model Simulating Postmortem Conditions, Mackenzie Taylor

Student Research Symposium

In fresh meat products, the most important attribute dictating consumer satisfaction is tenderness. Accordingly, researchers have rigorously studied the biochemical mechanisms involved in meat tenderization during aging, and found that proteolytic degradation of structural muscle proteins is one of the major mechanisms. Postmortem proteolysis is driven by endogenous proteases present in the muscle, and calpain-1 has been identified as the main protease involved in the tenderization process. Calpain-1 is a calcium-dependent protease that rely on calcium to become proteolytically active. Recently, mitochondria have garnered interest due to their ability to sequester and decrease cytosolic calcium concentration. However, it remains unclear …

Cytokine Indicators Of Inflammation In Mice Fed A Western Type Diet, Eliza Owens, Emily Mortensen

Student Research Symposium

Colorectal cancer is currently the second leading cause of cancer-related deaths in the United States. The risk of colon cancer increases in individuals who suffer from colitis, which is inflammation of the colon lining. Colitis is common in patients with inflammatory bowel disease (IBD). The development of colorectal cancer is complex and can be associated with dysbiosis of the gut microbiota, which has been shown to be affected by diet. Disruption of the gut microbiome can lead to the overgrowth of pathogenic bacteria which can contribute to disease. Pathogenic bacteria and other bacterial byproducts that manage to cross the epithelial …

Designing An Effective Employee Wellness Program: A Targeted Approach Using Employee Health Surveys, Sierra Giles

Student Research Symposium

Purpose – Given that employees typically spend a significant amount of their time at the workplace, an effective workplace wellness program has the potential to reduce employees’ health risks and improve their quality of life. The purpose of this project was to collect and assess baseline data on current health status for a Utah organization with approximately 400 employees and use the results to inform a comprehensive wellness program. Methods – Based on validated questionnaires from the literature, I developed an employee health screening survey which consisted of two parts – a biometric screening and a mixed methods health assessment …

Impact Of Fecal Microbiota Transfer (Fmt) On Phenotype Of Mice Fed A Standard Diet And A Western-Style Diet Using A Colitis-Associated Colorectal Cancer Model, Abbey Horrocks

Student Research Symposium

A variety of genetic and environmental factors can affect the composition of the human gut microbiota, including a poor diet. Western diets are typically associated with dysbiosis and other adverse health outcomes that are expressed phenotypically. The primary objective of this study is to determine the contribution of gut microbiota from mice donors who have previously consumed one of two basal diets: 1) the standard AIN93G diet, which is designed to promote rodent health; and 2) the total Western diet (TWD), which promotes inflammation-associated colorectal tumorigenesis. The donors’ microbiota were transferred to a cohort of mice who were fed either …

Roles Of Nad In Dna Repair And Response To Oxidative Stress, Micah Forbush

Student Research Symposium

It has become a common trend for people to start their families at a later age, often due to lifestyle choices like achieving career goals first and waiting to achieve financial stability. Along with this trend of increasing parental age comes another, the decrease in fertility. While it is well established that female fertility declines significantly with age, current research is showing that male fertility may be impacted just as much. NAD (Nicotinamide Adenine Dinucleotide) is an important biochemical cofactor in most metabolic reactions, and importantly, is it also essential for DNA repair. As age increases in humans, the amount …

Ὁ Δρόμος: Testing The Charge At Marathon, 490 Bce, Daniel Porter

Student Research Symposium

In 490 BCE, a heavily outnumbered Greek force of mainly Athenians fought an invading Persian army at Marathon to preserve their freedom. According to Herodotus, the Hellenes charged at a run (δρόμος) across the plain, a distance of eight stades (.9 miles), to engage and subsequently repel the Persians. Herodotus continues on to claim that this was the first Greek charge. The reason for this was that the phalanx, the Greek military formation, required close ranks and heavy armor, so running was not easy. Modern historians have questioned Herodotus’ veracity as well as the actual plausibility of this event due …

Fecal Microbiota Transfer (Fmt) From Tumor-Bearing Mice Fed The Total Western Diet (Twd) Does Not Contribute To A Higher Tumor Burden In Mice Fed A Healthy Diet, Porter Green

Student Research Symposium

Colorectal cancer (CRC) is the third most common cause of cancer death in the United States. Diet and gut microbiome have shown to influence the development of colitis associated colorectal cancer (CAC). For this study, the goal was to determine the association between colon inflammation, diet and microbiome in the development of CAC in mice. The primary objective of this study was to determine the contribution of gut microbiota from mice donors who have previously consumed one of two basal diets: 1) the standard AIN93G diet, which is designed to promote rodent health; and 2) the total Western diet (TWD), …

Effects Of Selection For Seed Size On Grazing‐Type Population Of An Inter‐Specific Hybrid (Pennisetum Purpureum × P. Glaucum), R. Usberti, J. A. Usberti Jr., P. B. Alcantara, A. T. Tsuhako

IGC Proceedings (1977-2023)

No abstract provided.

Allotrioemeis: Or, A Preposterous Preponderance Of Pins Produced, Strangely Doesburg

Phi Alpha Theta Pacific Northwest Regional Conference

Debellatus, the 1698 account of a witchcraft trial in Bargarren, Scotland, suggests new interpretations of witchcraft epidemiology. From late 1696 through 1697 a young girl named Christian Shaw experienced fits, visions, trances, and even levitation. More interesting, and decidedly the more tactile, was her tendency to demonstrate her affliction by vomiting various items: pins, straw, warm coals, balls of hair, and pieces of dung. Previous scholarship has dubbed this phenomena Allotriophagy, linking it to compulsive consumption conditions like Pica, seemingly overlooking their presence in contemporary Scottish medical literature. Furthermore, coincident accounts of stagecraft reveal numerous techniques were being practiced to …

Physiology Of Growth, Bhagyalakshmi K

Faculty work

No abstract provided.

Addressing Adherence And Barriers To Long-Tenn Elimination Diet Therapy Through Occupational Therapy In Order To Improve Quality Of Life In Adults With Eosinophilic Esophagitis, Alexis White

MOT Student Capstones

The six-food elimination diet {SFED) is an effective treatment approach for eosinophilic esophagitis {EoE), but it can be challenging and affect patients' quality of life. The aim of this study assesses patients' potential factors influencing adherence to long-term elimination diets. This project employed participant questionnaires to measure attitudes and practice regarding living with EoE; and an education presentation ppt with a pre- and post-survey for key stakeholders synthesizing research findings while aligning patient-provider interaction to promote improved diet adherence. Using data electronic surveys, analysis was conducted using electronic statistical software to determine patient barriers; and to determine accuracy and impact …

Understanding Benefits Of A Community Garden On Those Impacted By Food Insecurity, Taylor Boone

MOT Student Capstones

Occupational therapy professionals can support individual and community interventions for improved health and wellness. Occupational therapists have the unique ability to assess the multi-faceted contexts that impact an individual's and/or community's ability to participate in daily occupations and their level of occupational performance. Addressing nutrition can improve the individual's overall health and wellness and subsequently improve occupational performance, and ability to participate in daily occupations. Many community-based programs act as resources, or access, to improved nutritional intake for community members working towards food security. Occupational therapy has a role in these community-based programs to facilitate improved nutritional intake through functional …

Rotc Cadets' Nutrition Knowledge & Behaviors: A Pilot Study, Mikaela Blake, Annika Israelsen, Tori Gossling, Jacob Lamb

Student Research Symposium

The Reserve Officer Training Corps (ROTC) prepares college students for future military service. The ROTC includes a rigorous physical training program. As such, effective nutrition practices are necessary to maintain performance. The purpose of this study was to assess USU Cadets’ nutrition knowledge and practices to inform future research and intervention needs. Cadets were recruited through email and classroom announcements. Participants completed an online survey that gathered demographic, fitness, nutrition knowledge, nutrition behaviors, Intuitive Eating, perceived stress, and food security data. Results indicated that most cadets had a moderate knowledge of nutrition with a deficit in sports nutrition. This study …

Diabetes And Cancer: Metabolic Association, Therapeutic Challenges, And The Role Of Natural Products, Wamidh H. Talib, Asma Ismail Mahmod, Sara Feras Abuarab, Eliza Hasen, Amer A. Munaim, Shatha Khaled Haif, Amani Marwan Ayyash, Samar Khater, Intisar Hadi Al-Yasari, Lina T. Al Kury

All Works

Cancer is considered the second leading cause of death worldwide and in 2018 it was responsible for approximately 9.6 million deaths. Globally, about one in six deaths are caused by cancer. A strong correlation was found between diabetes mellitus and carcinogenesis with the most evident correlation was with type 2 diabetes mellitus (T2DM). Research has proven that elevated blood glucose levels take part in cell proliferation and cancer cell progression. However, limited studies were conducted to evaluate the efficiency of conventional therapies in diabetic cancer patients. In this review, the correlation between cancer and diabetes will be discussed and the …

Brachiaria Hybrids: Their Origin And Potential Forage Use, Esteban A. Pizarro, Michael D. Hare, John W. Miles

IGC Proceedings (1977-2023)

No abstract provided.

The Gada Test For Seed Storability, Don F. Grabe

All Articles

No abstract provided.

Physiology Of Seed Storage, James C. Delouche

All Articles

No abstract provided.

How Nutrition And Lower Socioeconomic Status Affects The Overall Health Of Rural Appalachian Residents, Johanna Dundon, Chloe Foutch, Renae Helm, Katherine Walsh

Epsilon Sigma at-Large Research Conference

No abstract provided.

Healthcare Disparities Among Incarcerated Pregnant Women, Molly Carpenter, Halim Oluwatunmise, Whitney Shipley, Ojiugo Udensi

Epsilon Sigma at-Large Research Conference

No abstract provided.