Digital Commons Network^™

Ignatian Information Literacy: Applying The Ignatian Pedagogical Paradigm To Library Instruction, Anthony Tardiff

Jesuit Higher Education: A Journal

Instruction librarians in higher education specialize in information literacy, which is the set of skills needed to interact effectively with information. The guiding document for library instruction, the Association of College and Research Libraries’ (ACRL) Framework for Information Literacy, calls for imparting the foundational wisdom and self-awareness which underlie these skills. Unfortunately, most library instruction is delivered in 50- or 75-minute “one-shots” focusing on the technical skills of searching library resources, which makes deeper information literacy instruction a challenge. One way to meet this challenge is to utilize the Ignatian Pedagogical Paradigm (IPP), which shares with the ACRL Framework …

Determine The Effects Of Propionate On The Interactions Between Macrophages And Listeria Monocytogenes, Stephanie M. Johnson

Honors Theses

Listeria monocytogenes is an opportunistic and intracellular foodborne pathogen that can be deadly in high risk populations. During infection in the human body, L. monocytogenes may encounter macrophages, a type of white blood cell that is critical in innate immune response both by directly targeting invading pathogens and by eliciting adaptive immune responses. During intestinal as well as peripheral infections, both L. monocytogenes and macrophages may encounter propionate, a common gut microbiome metabolite. Although propionate is shown to have various regulatory and nutritional functions, its effects on infection outcome is not well understood. Therefore, the goal of this research is …

Chipatala Cha Pa Foni, Malawi's 'Health Center By Phone,' Improving Information Given About Pregnancy-Related Symptoms, Breakthrough Research, Villagereach

Reproductive Health

The Health Center by Phone, or "Chipatala cha pa Foni" (CCPF), was developed by Malawi’s Ministry of Health and VillageReach as a community-based hotline in the Balaka district of Malawi. CCPF was identified as an existing national health strategy with potential for providing Malawi’s women and their families important postpartum hemorrhage information. Because CCPF archives de-identified audio recordings of all calls, 28 telephone transcripts were qualitatively examined to assess whether women experiencing pregnancy-related complications such as postpartum bleeding call CCPF, and how hotline workers respond to them.

The Communal Integration Of Nutrition-Related Cultural Assets Of The Latinx Population In The Greater Dayton Area, Hannah G. Waters

Honors Theses

Due to a series of social determinants, the Latinx population currently living in the United States is suffering from a multitude of health disparities. Many of these disparities are nutrition-related, as the health issues that most disproportionately affect the Latinx population are obesity and diabetes. In order to treat these dietary-related health disparities, one must examine the complex aggregation of factors that work to influence specific dietary habits. Dietary habits are impacted by a series of individual, social and environmental factors. Moreover, in the case of Latinx nutrition, the level of acculturation, or cultural adjustment, plays a crucial role in …

The Effects Of Telehealth On Patient Satisfaction And Information Recall For Breast Cancer Survivors During Covid-19, Stacey Teicher

Doctoral Projects

The coronavirus (COVID-19) pandemic has changed how cancer survivorship care is delivered. (Al‐Shamsi, 2020). To protect vulnerable breast cancer patients, health care providers are moving towards telecommunication such as telephone, video, and secure messaging (electronic mail) versus in-person visits to connect with their patients (Segelov et al., 2020) during this pandemic. Breast cancer survivorship visits can be safely deferred from in-person visits to telehealth visits (Dietz et al., 2020). This doctoral project examines the impact of transitioning from in-person to telehealth (telephone or video) visits on patient satisfaction and recall of information for breast cancer survivors reviewing their Survivorship …

Anti-Inflammatory And Immunomodulatory Properties Of Fermsented Plant Food, Roghayeh Shahbazi, Farzaneh Sharifzad, Rana Bagheri, Nawal Alsadi, Hamed Yasavoli-Sharahi, Chantal Matar

Chemistry Faculty Publications and Presentations

Fermented plant foods are gaining wide interest worldwide as healthy foods due to their unique sensory features and their health-promoting potentials, such as antiobesity, antidiabetic, antihypertensive, and anticarcinogenic activities. Many fermented foods are a rich source of nutrients, phytochemicals, bioactive compounds, and probiotic microbes. The excellent biological activities of these functional foods, such as anti-inflammatory and immunomodulatory functions, are widely attributable to their high antioxidant content and lactic acid-producing bacteria (LAB). LAB contribute to the maintenance of a healthy gut microbiota composition and improvement of local and systemic immunity. Besides, antioxidant compounds are involved in several functional properties of fermented …

Tennessee Farm Bureau News - May 2021, Tennessee Farm Bureau Federation

Tennessee Farm Bureau News

No abstract provided.

Type 2 Diabetes Subgroups, Risk For Complications, And Differential Effects Due To An Intensive Lifestyle Intervention, Michael P Bancks, Haiying Chen, Ashok Balasubramanyam, Alain G Bertoni, Mark A Espeland, Steven E Kahn, Scott Pilla, Elizabeth Vaughan, Lynne E Wagenknecht

Faculty, Staff and Students Publications

OBJECTIVE: We reevaluated the Action for Health in Diabetes (Look AHEAD) intervention, incorporating diabetes subgroups, to identify whether intensive lifestyle intervention (ILI) is associated with differential risk for cardiovascular disease (CVD) by diabetes subgroup.

RESEARCH DESIGN AND METHODS: In the Look AHEAD trial, 5,145 participants, aged 45-76 years, with type 2 diabetes (T2D) and overweight or obesity were randomly assigned to 10 years of ILI or a control condition of diabetes support and education. The ILI focused on weight loss through decreased caloric intake and increased physical activity. To characterize diabetes subgroups, we applied k-means clustering to data on age …

Acetyl-Coa And Metabolite Fluxes Regulate White Adipose Tissue Expansion, Jessica B Felix, Aaron R Cox, Sean M Hartig

Faculty, Staff and Students Publications

White adipose tissue (WAT) depends on coordinated regulation of transcriptional and metabolic pathways to respond to whole-body energy demands. We highlight metabolites that contribute to biosynthetic reactions for WAT expansion. Recent studies have precisely defined how byproducts of carbohydrate and lipid metabolism affect physiological and endocrine functions in adipocytes. We emphasize the critical emerging roles of short-chain fatty acids (SCFAs) and tricarboxylic acid (TCA) cycle metabolites that connect lipogenesis to WAT energy balance and endocrine functions. These insights address how adipocytes use small molecules generated from central carbon metabolism to measure responses to nutritional stress.

Associations Of Abdominal Pain And Psychosocial Distress Measures With Health-Related Quality-Of-Life In Pediatric Healthy Controls And Irritable Bowel Syndrome, John M Hollier, Danita I Czyzewski, Mariella M Self, Yan Liu, Erica M Weidler, Miranda A L Van Tilburg, James W Varni, Robert J Shulman

Faculty, Staff and Students Publications

BACKGROUND: Children with irritable bowel syndrome (IBS) have lower health-related quality-of-life (HRQOL) than healthy controls (HC). Abdominal pain and psychosocial distress are negatively associated with HRQOL, although their relative effect is unclear.

AIM: The aim of this study was to compare the relative associations of abdominal pain and psychosocial distress with HRQOL in HC and IBS.

STUDY: Baseline abdominal pain, psychosocial distress, and HRQOL measures were obtained from HC and IBS pediatric clinical trial participants. Regression assessed which measures were most strongly associated with Physical and Psychosocial HRQOL separately by group. Interaction analyses examined group differences in the associations of …

Particle Tracking Reveals Pelagic Red Crabs As Indicators Of Climate-Driven Range Expansion In The California Current, Elizabeth Saraf

Senior Honors Projects

Since their first recorded occurrence in 1859, Pelagic Red Crabs (PRC; Pleuroncodes planipes) have experienced increased frequency of episodic mass stranding events in the Eastern Pacific Ocean. PRC’s are transported over 1,000 km northward of their central domain from the coast of central Baja California, Mexico. They have been reported by the thousands on the beaches of central and southern California. Their presence influences the surrounding ecosystem and commercial fisheries because they are nutritional prey items and large predators change their diet to incorporate PRC’s when they are available. Seasonal coastal currents and the California Undercurrent transport warmer waters …

Nutritional Data And Corresponding Performance Impacts Of Uri Student-Athletes, Abigael Fenbert

Senior Honors Projects

This research project investigates the diets of various sport athletes at the University of Rhode Island. The question that this project aims to answer is if our athletes are meeting recommended daily values nutritionally, and if not, why? Research continues to grow regarding how performance implications are tied to varying nutritional disparities for athletes. Various studies show malnourishment leads to performance decline, increased injury risk, and improper recovery. This is influenced by factors such as deficits in caloric intake, macronutrient and micronutrient availability, and dehydration. For college athletes, a lack of food availability and nutritional knowledge leaves them especially predisposed …

A Story Told, Carly Caldarella

Senior Honors Projects

How do we educate our future generations about topics that are difficult to discuss? Oftentimes, children ask us questions that make us think, "How do I respond to this?" It is essential for our young generations to understand the history of racism, its present manifestations, and solutions and methods of action in order for a bright and revolutionary future. It is not always a simple task for children to comprehend such intricate topics. However, through text and pictures in storybooks, children can better grasp the concepts of such subject matter. "A Story Told" shares the story of young children in …

Composition, Diversity, Abundance, And Spatial Variation In The Floral Nectar Mycobiome Of Rhododendron Catawbiense And Lobelia Cardinalis, Ayesha Khan

Undergraduate Honors Theses

Plant nectar microbiome, primarily consisting of fungi and bacteria, can qualitatively and quantitively alter the floral rewards by exploiting the chemical composition of the nectar which can thus impact plant-pollinator interactions, and ultimately affect plant reproductive success. Evidence suggests that changes in the microenvironmental conditions across various spatial gradients can induce changes in the floral nectar microbiome, which can account for microbial variation not only across plant species, but also within. Furthermore, nectar microbiome is also contingent on the pollinator systems and nectar quality. In this study, we used Rhododendron catawbiense (bee-pollinated; highly toxic nectar) and Lobelia cardinalis (hummingbird-pollinated; mildly …

Getting Excited For Our Class: Instructor Immediacy, Rapport, And Effects For Students, Emily Napier

Undergraduate Honors Theses

This thesis examined the relationships between instructors and students to determine the effects of prosocial instructor behavior on the college student experience for both in-person and online learning. Study One examined instructor rapport with students and verbal and nonverbal immediacy behaviors in face-to-face classes. Students reported on how their instructor constructed the classroom climate and perceptions of their instructor’s behavior. Results indicated that students’ perceptions of instructor verbal and nonverbal immediacy behaviors were related to lower student communication apprehension with instructors; whereas perceived classroom rapport was related with higher perceptions of their instructor’s credibility and was also related with a …

Leptin Activation Of Metabolically-Related Hypothalamic Neurons, Kailee Hixon

Undergraduate Honors Theses

Obesity is often associated with multiple other clinical conditions, including hypertension and cardiovascular disease. Currently, more than one-third of the world’s population is classified as obese. Leptin is a neuropeptide that is released from adipose cells and is responsible for reducing appetite and increasing metabolism. Leptin also has a role in the activation of cardiovascular and metabolic pre-sympathetic neurons and has been reported to increase blood pressure and heart rate. Thus, understanding the activation of the autonomic nervous system by leptin has implications in the development and safety of drugs to avoid activation of cardiovascular pre-sympathetic neurons. This is important …

Omega-3 Fatty Acid Fortification Of Marinara Sauce, Hannah Collie

Undergraduate Honors Theses

In westernized culture, there is a deficit of healthy fats in the average person’s diet. Decreased intake of omega-3 fatty acids has been correlated to many different conditions such as cardiovascular disease, cancer, and chronic inflammatory issues. The “Mediterranean Diet” has been proposed as an ideal way to combat these issues. This diet promotes fish as a protein source and as a way to increase intake of essential polyunsaturated fatty acids. Due to location and dietary trends, fish is less often the main component of Northeast Tennessee's diet. This study investigated ways to fortify a more commonly consumed food in …

The Impact Of Prolonged Estrogen Deficiency On Cardiac Hypertrophy Following Chronic Sympathetic Stimulation, Isabelle Krueger

Undergraduate Honors Theses

Cardiovascular disease (CVD) is the leading cause of death for both men and women in developed countries. Compared to age-matched males, premenopausal women experience lower rates of CVD but this increases after menopause. A central feature in CVD is changes in sympathetic regulation leading to pathological changes such as cardiac hypertrophy characterized by changes in cardiomyocyte size due to overcompensation of the muscle following injury. The goal of this research is to study the effect of prolonged estrogen loss on cardiac hypertrophy following chronic sympathetic stimulation. Female mice were ovariectomized at 10 weeks of age and treated with Isoproterenol to …

Picky Eating In Children: Associations With Iq And Executive Functioning, Ara Nazmiyal

Senior Honors Papers / Undergraduate Theses

Picky eating is an under-researched behavior in children. The current study aims to assess what behaviors correlate with picky eating to better understand potential risk factors for Anorexia Nervosa. 111 children were evaluated at 5 and 6 years old, and a subset was evaluated again at 7 and 8 years old (n=36). Executive function and IQ were evaluated using parent reports and behavioral measures at baseline. Picky eating was reported by a parent questionnaire. Results showed deficits in shifting to be a predictor of higher picky eating behaviors at ages 5-6 years. Additionally, children who were reported extremely picky eaters …

What Consumers Actually Know: The Role Of Objective Nutrition Knowledge In Processing Stop Sign And Traffic Light Front-Of-Pack Nutrition Labels, J. Craig Andrews, Richard G. Netemeyer, Scot Burton, Jeremy Kees

Marketing Faculty Research and Publications

Examining the effects of what consumers actually know (i.e., objective knowledge) is an important gap in front-of-pack (FOP) nutrition research. In experiments with over 2,000 primary food shoppers, we examine the moderating impact of objective nutrition knowledge on key FOP nutrition symbols (Stop Sign labels, Traffic-Light labels, and a control) for effects on nutrient perceptions, nutrition use accuracy, disease risk, brand attitudes, and purchase intentions. Results support the effectiveness of the Stop Sign label over the Traffic Light label for key outcome measures, with the Traffic Light label performing better on nutrition use accuracy. Importantly, those with greater objective nutrition …

Indirect Impact Of Soil Microbial Communities On Plant-Aphid Interactions, Zachary Tiemann

Master's Theses

The community dynamics of soil micro-environments are influenced by root, fungal, and bacterial exudates that can preferentially select for functional classes of microbes. Arbuscular mycorrhizal fungi (AM) fungi and plant growth promoting rhizobacteria (PGPR) are members of this community form symbiotic relationships with plants and play an important role in triggering induced systemic resistance (ISR), resulting in defensive “priming.’ Consequently, ‘primed’ plants can activate stronger and faster defense responses to future attacks by pathogens and insects. The biological system in this study involved four genotypes of barrel medic plants (Medicago truncatula), pea aphids (Acyrthosiphon pisum), and microbial communities present in …

Evaluation Of Α-Pyrrolidindovalerophenone (Α-Pvp) And Its Isomers In Male And Female Sprague-Dawley Rats Trained To Discriminate Mdpv, Kaley Cargile

Masters Theses

Recreational use of synthetic cathinones, 3,4-methylenedioxypyrovalerone (MDPV) and α‐pyrrolidinovalerophenone (α‐PVP), has become increasingly popular, thus prompting characterization of their behavioral and neurochemical effects. MDPV has been studied for several years now, though there is still much unknown about α‐PVP, and its isomers. The primary objective of this study was to characterize the discriminative effects of α‐PVP and its isomers in comparison to MDPV. Male and female Sprague-Dawley rats were trained to discriminate 0.5mg/kg MDPV from saline injections under a fixed ratio 20 (FR 20) schedule of food reinforcement. Substitution tests were conducted with MDPV (0.05-0.5mg/kg), α‐PVP (0.05-0.5mg/kg), (S)-α‐PVP (0.05-1mg/kg) and …

How Historic Shipwrecks Influence Dispersal Of Deep-Sea Microbiomes, Rachel Moseley

Master's Theses

This thesis investigates how historic shipwrecks potentially shape dispersal of deep-sea microbiomes. Processes impacting dispersal of microbiomes around artificial structures in the ocean and how they connect to other deep-sea habitats is unknown. Dispersal processes are explained for some macroorganisms by theories in ecology, specifically the Theory of Island Biogeography and the Wooden Stepping Stone hypothesis. These have not been investigated for microorganisms, and thus this work will probe if they are applicable to microbial biogeography in this habitat. Experiments were conducted to establish new “island-like” features in near proximity (25-125 m) to wooden-hulled historic shipwrecks in the northern Gulf …

An Evaluation Of Activity In A Colonial Maya Cemetery Using Femoral Cross-Sectional Analysis, Casey Lejeune

Master's Theses

Cortical bone formation in the population of Tipu, a colonial visita site in Belize, was examined here to reveal factors of their activity and address the possibility of a status-based burial plan. To answer this question, this research examined the endosteal surface of the midshaft femur using digital imaging methods. The femora from 70 individuals were photographed and examined using the BoneJ plugin in ImageJ software. The cortical bone area was compared to additional variables, including sex, age, stature, pilastric index, and burial location. It was hypothesized that sex, age, and stature would correlate with cortical bone area similarly across …

A Hindbrain Dopaminergic Neural Circuit Prevents Weight Gain By Reinforcing Food Satiation, Yong Han, Guobin Xia, Yanlin He, Yang He, Monica Farias, Yong Xu, Qi Wu

Children’s Nutrition Research Center Staff Publications

The neural circuitry mechanism that underlies dopaminergic (DA) control of innate feeding behavior is largely uncharacterized. Here, we identified a subpopulation of DA neurons situated in the caudal ventral tegmental area (cVTA) directly innervating DRD1-expressing neurons within the lateral parabrachial nucleus (LPBN). This neural circuit potently suppresses food intake via enhanced satiation response. Notably, this cohort of DAcVTA neurons is activated immediately before the cessation of each feeding bout. Acute inhibition of these DA neurons before bout termination substantially suppresses satiety and prolongs the consummatory feeding. Activation of postsynaptic DRD1LPBN neurons inhibits feeding, whereas genetic deletion of Drd1 within the …

N-3 Fatty Acid Biomarkers And Incident Type 2 Diabetes: An Individual Participant-Level Pooling Project Of 20 Prospective Cohort Studies, Frank Qian, Andres V Ardisson Korat, Fumiaki Imamura, Matti Marklund, Nathan Tintle, Jyrki K Virtanen, Xia Zhou, Julie K Bassett, Heidi Lai, Yoichiro Hirakawa, Kuo-Liong Chien, Alexis C Wood, Maria Lankinen, Rachel A Murphy, Cecilia Samieri, Kamalita Pertiwi, Vanessa D De Mello, Weihua Guan, Nita G Forouhi, Nick Wareham, Interact Consortium Frank B Hu, Ulf Riserus, Lars Lind, William S Harris, Aladdin H Shadyab, Jennifer G Robinson, Lyn M Steffen, Allison Hodge, Graham G Giles, Toshiharu Ninomiya, Matti Uusitupa, Jaakko Tuomilehto, Jaana Lindström, Markku Laakso, David S Siscovick, Catherine Helmer, Johanna M Geleijnse, Jason H Y Wu, Amanda Fretts, Rozenn N Lemaitre, Renata Micha, Dariush Mozaffarian, Qi Sun

Children’s Nutrition Research Center Staff Publications

Objective: Prospective associations between n-3 fatty acid biomarkers and type 2 diabetes (T2D) risk are not consistent in individual studies. We aimed to summarize the prospective associations of biomarkers of α-linolenic acid (ALA), eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA), and docosahexaenoic acid (DHA) with T2D risk through an individual participant-level pooled analysis.

Research design and methods: For our analysis we incorporated data from a global consortium of 20 prospective studies from 14 countries. We included 65,147 participants who had blood measurements of ALA, EPA, DPA, or DHA and were free of diabetes at baseline. De novo harmonized analyses were performed …

Integration Of Palliative Care For Improving Quality Of Life In Patients With Chronic Obstructive Pulmonary Disease, Christina Davis Rasanen

Physician Assistant Scholarly Project Papers

The purpose of this scholarly project is to determine if the integration of palliative care into COPD management provides an improvement in symptom burden associated with quality of life and end of life care when compared to the standard of care. A review of the literature was performed using the following electronic databases, and the use of keywords and mesh terms were used to define the set of literature that would be critically analyzed. A total of 16 articles achieved the necessary criteria for review and critical assessment. The literature reviewed various aspects related to symptom burden and symptom management …

Effect Of Cftr Modulators On Respiratory Function In Adults With Cystic Fibrosis, Melissa Severson

Physician Assistant Scholarly Project Papers

Cystic Fibrosis (CF) is an autosomal recessive disorder that shortens one’s life due to its effect on the cystic fibrosis transmembrane regulator (CFTR) gene. CFTR modulator medications can correct the CFTR gene and consist of a potentiator (ivacaftor), and corrector (lumacaftor, tezacaftor and elexacaftor). This research and literature review sought to evaluate if lung function improved in an individual with genetically confirmed CF after being started on CFTR modulator medications. To complete the review, six databases were searched which included: CINAHL, PubMed, Clinical Key, Cochrane Library, Embase and Dynamed Plus. Both keyword and mesh terms were used to define a …

Effectiveness Of Diet/Exercise In Prevention Of Gestational Diabetes Mellitus And Associated Cesarean Section Delivery, Jonathyn Andrew Marx

Physician Assistant Scholarly Project Papers

Gestational diabetes mellitus (GDM) is becoming a more common diagnosis during pregnancy. GDM is defined as glucose intolerance diagnosed during pregnancy. Women diagnosed with GDM during pregnancy are at an increased risk for emergent or planned cesarean section delivery and the development of overt diabetes mellitus post pregnancy. Complications related to GDM include eclampsia, macrosomia, shoulder dystocia, stillbirth, and cesarean section delivery. Initial treatment consists of diet and exercise and if glucose can not be controlled then pharmacotherapy is introduced. A literature review was performed utilizing scientific databases, mesh terms, and keywords to gather statistically relevant research to analyze the …

Treatment Of Male Obesity-Related Secondary Hypogonadism And The Effects On Fertility, Julie E'Lane Harmon

Physician Assistant Scholarly Project Papers

The link between obesity and testosterone deficiency has often been a topic of research. Male obesity-related secondary hypogonadism (MOSH) is often underdiagnosed in the young male population. The current standard of care for hypogonadism in the older male population typically includes testosterone replacement therapy (TRT). The purpose of this study is to highlight available treatment options for MOSH in the younger population and the various effects on fertility. The method utilized was a systematic review of the current literature that targeted obese males below the age of 65 treated for secondary hypogonadism. The review excluded articles published longer than ten …