Digital Commons Network^™

Atrx Inactivation And Idh1-R132h Drive Preferential Sensitivity To Proton Vs. X-Ray Radiotherapy In Glioma Stem Cells, Ángel Adrián Garcés

Dissertations and Theses (Open Access)

Background: Glioma Stem Cells (GSCs) are self-renewable, treatment resistant cells in the glioma tumor mass known to promote tumor development. In contrast to traditional photon-based radiation therapy (XRT), proton radiation therapy (PRT) may induce more complex DNA damage and therefore might have the potential to eliminate GSCs. Although previous studies have individually linked IDH mutations, specifically IDH1^R132H, and ATRX inactivating mutations to improved patient outcomes and suppressed DNA damage repair compared to their respective wild-types, the mechanisms by which these two genetic alterations interact in GSCs treated with PRT compared to XRT are currently unknown. We hypothesize that …

Section 230 And The Problem Of Social Cost, Stanley M. Besen, Philip L. Verveer

Journal of Law and Policy

This Article employs, with certain modifications, the framework developed in Ronald Coase’s classic article, “The Problem of Social Cost,” to analyze the current debate over Section 230 of the Communications Decency Act. This provision absolves interactive computer services, also known as platforms, from liability when they disseminate materials that cause “harm” to third parties, “harm” that can take the form of compensable damage of a sort found in ordinary tort cases but also can include broader injuries to social order and cohesion in the form of such things as hate speech and misinformation. The Article begins by pointing out that, …

A Close Association Of Freedom From Pain, Migraine-Related Functional Disability, And Other Outcomes: Results Of A Post Hoc Analysis Of Randomized Lasmiditan Studies Samurai And Spartan, Richard B. Lipton, Simin K. Baygani, Stewart J. Tepper, John H. Krege, Raghavendra Vasudeva, Eric M. Pearlman, Paula M. Hauck, Li Shen Loo

Dartmouth Scholarship

Background: While pain freedom at 2 h is a key primary outcome for current trials for acute treatment of migraine, the relationship between the degree of head pain and other efficacy measures at 2 h has rarely been explored. Following lasmiditan treatment of a migraine attack with moderate or severe head pain, we contrast those who achieve pain freedom with those who achieve mild pain but not pain freedom 2 h post dosing. Methods: Patient-level data were pooled across studies and treatment arms from two Phase 3 trials comparing lasmiditan and placebo, SAMURAI and SPARTAN. This post hoc analysis assessed …

English As A Foreign Language Preservice Teachers’ Technology Integration In Teaching Speaking Skills: A Study From Indonesia, I Putu Indra Kusuma

Dissertations

The novel coronavirus, namely COVID-19, has drastically forced schools and universities around the globe to implement emergency remote teaching (henceforth, ERT) in online forms. During this ERT, the personal computer, internet-accessible devices, and computer programs have expanded the opportunities of language learners to obtain more authentic materials and learning experiences. Moreover, technology enables students to record and store their speaking performance in digital forms, accommodating a new reform in English language teaching. Very little is known about how English as a foreign language (henceforth, EFL) preservice teachers, especially student teachers, implement technology in teaching speaking skills during their practice teaching. …

Kansas Speaks Fall 2021 Statewide Public Opinion Survey, Brett Zollinger Ph.D., Jian Sun Ph.D., Michael Walker M.S., Marisa M. Johnson M.B.A.

Docking Institute of Public Affairs

The 2021 Kansas Speaks fall survey was conducted from December 4 to December 17, 2021. A panel of 523 adult residents of Kansas age 18 and older were surveyed online to assess their attitudes and opinions regarding various issues of interest to Kansas citizens.

Effects Of Nitrogen Management And Cultivar On Strawberry Production Under Disease Pressure, Kamille A. Garcia-Brucher

Master's Theses

Effects of nitrogen management and cultivar on strawberry production under disease pressure

Kamille Garcia-Brucher

California strawberry growers face increasing regulatory pressures to manage nitrogen (N) applications in their production system. Standard practice in the California strawberry industry is to apply a synthetic pre-plant controlled release fertilizer (CRF) to ensure the crop has sufficient N during winter establishment. Some research from the UC Cooperative Extension suggests this practice is not efficient at delivering N to the crop since most of the N is released from CRF before strawberry crop N uptake is significant. Another concern for California strawberry growers is loss …

Secure Data Collection And Analysis In Smart Health Monitoring, Pei Huang

All Dissertations

Smart health monitoring uses real-time monitored data to support diagnosis, treatment, and health decision-making in modern smart healthcare systems and benefit our daily life. The accurate health monitoring and prompt transmission of health data are facilitated by the ever-evolving on-body sensors, wireless communication technologies, and wireless sensing techniques. Although the users have witnessed the convenience of smart health monitoring, severe privacy and security concerns on the valuable and sensitive collected data come along with the merit. The data collection, transmission, and analysis are vulnerable to various attacks, e.g., eavesdropping, due to the open nature of wireless media, the resource constraints …

Effects Of Food-Grade Nonionic Surfactants On The Iron-Catalyzed Oxidative Stability Of Lycopene In Oil-In-Water Emulsions, Jeffrey Allen Bowles

All Dissertations

In this research a novel method for the rapid, direct measurement of oxidative lycopene degradation in oil-in-water emulsions via colorimetric means was developed. This analytical method was used to conduct experiments monitoring the degradation of lycopene-containing oil-in-water emulsions of decane spontaneously formed in the presence of nonionic surfactants (Span and Tween) of different tail lengths and molar ratios. The structure and ratio of these nonionic surfactants was manipulated to probe the mechanism of lycopene stabilization when iron-catalyzed oxidation was the main pathway of degradation, as controlled by pH and oil phase selection. The effect of addition of chloride salts with …

“I Thought I Was Going To War”: Experiences Of Health-Care Workers During The Covid-19 Pandemic – An Exploration Of Projectcope, Smith F. Heavner

All Dissertations

The COVID-19 pandemic continues to strain health-care systems throughout the world. While early reports compared its impacts to other contemporary disease outbreaks (e.g., SARS and MERS), it quickly became apparent that COVID-19 would dwarf these contemporary crises, escalating to a scale more on par with the 1918 influenza outbreak. This disaster will have unprecedented effects on health-care workers, among whom burnout was already a serious concern. Burnout and linked phenomena moral distress, compassion fatigue, and secondary trauma are associated with increased turnover and intent to leave health-care professions, decreased quality of care delivered to patients, and poor mental and physical …

Enhancing The Performance Of Text Mining, Farah Mahmoud Al Shanik

All Dissertations

The amount of text data produced in science, finance, social media, and medicine is growing at an unprecedented pace. The raw text data typically introduces major computational and analytical obstacles (e.g., extremely high dimensionality) to data mining and machine learning algorithms. Besides, the growth in the size of text data makes the search process more difficult for information retrieval systems, making retrieving relevant results to match the users’ search queries challenging. Moreover, the availability of text data in different languages creates the need to develop new methods to analyze multilingual topics to help policymakers in governmental and health systems to …

An Assessment Of The Needs Of School-Based Agricultural Educators And Other Professionals In Agricultural Service Agencies For A Professional Online Master’S Degree In Agricultural Education, Maria Mercedes Rossi

All Dissertations

Online learning is one form of distance education mediated through information and communications technology such as the Internet or other technologies. The teaching content is delivered online, and instructors develop teaching modules that enhance their learning and interactivity (student-student, teacher-student, and content-student). Using social cognitive theory (SCT) concepts, the research team developed and validated a multidimensional instrument tool to assess the needs for a professional online master’s degree in agricultural education. The study aimed to assess participants’ readiness and motivations to learn online and identify participants’ needs and experience with online learning. Participants’ perceptions of online learning were assessed and …

The Future Of Humankind: Comparative Cross-Cultural Study Of Youth Environmental Engagement And Environmental Outcomes, Lyudmyla Tsykalova

All Dissertations

Throughout history, the relationship of humans with nature evolved with culture. Climate change calls for a cultural shift in how we relate to nature and fellow humans, pointing to the need to rethink most human activities. Youth are frequently seen as agents of change. However, the widespread understanding that youth environmental engagement is necessary and brings more sustainable outcomes has almost no supporting empirical evidence. Research is needed to reveal whether youth environmental engagement is related to climate policies and ecological consequences and how this engagement varies across cultures.

Based on data from over 300,000 15-year-olds from 40 countries across …

Interventions To Increase Prospective Teacher Candidates' Praxis Ii Content Exam Scores, Takara Hart

All Dissertations

Teacher shortages are a pervasive issue in South Carolina’s public schools. Some prospective teacher candidates have shown obstacles in meeting the minimum required Praxis II Content exam score. The purpose of this qualitative phenomenological study was to explore and develop specific Praxis II Content exam interventions to improve scores for six prospective teacher candidates in South Carolina. All participants were trying to meet the licensure exam requirement for various alternative certification programs. Malcolm Knowles’ Andragogy Adult Learning Theory guided the study as a theoretical framework, and Lev Vygotsky’s Socio-Cultural Constructivism provided the conceptual frame. Descriptive coding and analysis, using Dedoose …

A Youthful Metaverse: Towards Designing Safe, Equitable, And Emotionally Fulfilling Social Virtual Reality Spaces For Younger Users, Divine Maloney

All Dissertations

Social virtual reality (VR) represents the modern rendition of the metaverse, this dissertation aims to fill the research gaps while highlighting trends of youth in VR. The scientific contributions of this research include 1) expanding the current HCI understanding of the social dynamics and the interactions of teens in emerging novel online digital spaces; 2) bridging two research areas that have not been widely studied in HCI, social VR and young users in social VR; and 3) generating design implications to inform the design of future social VR platforms to better support and protect teens’ online social experiences, results which …

El Leñador, December 2021, El Leñador Staff

El Leñador Newspaper

El Leñador is an English and Spanish newspaper produced by Humboldt State University students. Our staff cover and provide news to Latinx and other diverse communities on campus and in Humboldt County. We are committed to providing relevant news and expanding the representations and stories told about people of color and other marginalized groups. Our work helps create more social, political and cultural diversity in local media.

El Leñador es un periodico en español y inglés producido por estudiantes de la Universidad Estatal de Humboldt. Nuestro personal cubre y provee noticias a la comunidad Latinx y otras comunidades diversas en …

Comparing Organic And Conventional Yield Responses To Climate Variations, Joost Wilken Meyer

Graduate Theses and Dissertations

This thesis compares the responses of organic yields and conventional yields towards climate variations. To achieve this objective, weather variables such as growing season weather conditions (average temperature, precipitation, cloud cover, relative humidity, drought index), weather anomalies, the occurrence of severe or extreme droughts and excessive rainfalls, are combined with 23 data sets gathered from previous studies that compare organic and conventional yields from the same location and time periods. To narrow the scope, the thesis focuses on soybean, maize, and wheat production in Europe and North America. Study-level fixed-effects models are used to control for any time-invariant factors such …

Exploring Unpredictability In Augusta Read Thomas' Six Piano Etudes And Traces, Gianne Ge Zhu

Dissertations, 2020-current

Augusta Read Thomas (1964-) composes in many genres. Her music is often filled with subtle nuances of articulation and color, and contains many intentional "surprises." Thomas achieves these sound effects by applying three compositional principles: by providing a score with detailed instructions and additional information that result in the feeling of "spontaneity"; by using her "organic" language to transform the connections to the past or to living composers; and by considering all musical elements as one "gestalt" to form her music.

Six Piano Etudes (1996-2005) and Traces (2006) are filled with "surprises," in which the listener can discover elements of …

The Technologization Of Insurance: An Empirical Analysis Of Big Data And Artificial Intelligence’S Impact On Cybersecurity And Privacy, Shauhin A. Talesh, Bryan Cunningham

Utah Law Review

This Article engages one of the biggest issues debated among privacy and technology scholars by offering an empirical examination of how big data and emerging technologies influence society. Although scholars explore the ways that code, technology, and information regulate society, existing research primarily focuses on the theoretical and normative challenges of big data and emerging technologies. To our knowledge, there has been very little empirical analysis of precisely how big data and technology influence society. This is not due to a lack of interest but rather a lack of disclosure by data providers and corporations that collect and use these …

Infodemic: The Effect Of Death-Related Thoughts On News-Sharing, Amy J. Lim, Edison Tan, Tania Lim

Research Collection School of Social Sciences

Research on the sharing of fake news has primarily focused on the manner in which fake news spreads and the literary style of fake news. These studies, however, do not explain how characteristics of fake news could affect people’s inclination toward sharing these news articles. Drawing on the Terror Management Theory, we proposed that fake news is more likely to elicit death-related thoughts than real news. Consequently, to manage the existential anxiety that had been produced, people share the news articles to feel connected to close others as a way of resolving the existential anxiety. Across three experimental studies (total …

The Pandemic As Political Opportunity: Jokowi’S Indonesia In The Time Of Covid-19, Charlotte Setijadi

Research Collection School of Social Sciences

In mid-2021, the Delta strain of the Covid-19 virus caused a second wave of transmissions and deaths in Indonesia at a scale much greater than what was seen in 2020. In this paper, I examine what the Indonesian government’s handling of the Covid crisis in 2021 reveals about the priorities of President Joko Widodo (Jokowi), as well as his political agenda and attitude towards the country’s democracy, as he strives to cement his legacy. I argue that, while devastating, the Covid-19 pandemic has given Jokowi the opportunity to push through long-planned economic and political reforms. Furthermore, I contend that, under …

Functional Singular Spectrum Analysis, Hossein Haghbin, Seyed Morteza Najibi, Rahim Mahmoudvand, Jordan Trinka, Mehdi Maadooliat

Mathematical and Statistical Science Faculty Research and Publications

In this paper, we develop a new extension of the singular spectrum analysis (SSA) called functional SSA to analyze functional time series. The new methodology is constructed by integrating ideas from functional data analysis and univariate SSA. Specifically, we introduce a trajectory operator in the functional world, which is equivalent to the trajectory matrix in the regular SSA. In the regular SSA, one needs to obtain the singular value decomposition (SVD) of the trajectory matrix to decompose a given time series. Since there is no procedure to extract the functional SVD (fSVD) of the trajectory operator, we introduce a computationally …

The Parthenon, December 1, 2021, Xena Bunton, Isabella Robinson, Madison Perdue, Abby Hanlon, Catherine Blankenship, Zach Hiser, Tyler Spence, Carter Truman, Tyler Kennett, Abby Ayes, Noah Hickman

The Parthenon

No abstract provided.

Us Consumers' Perceptions Of Raw And Cooked Broken Rice, Matthew G. Richardson, Philip Glen Crandall, Han-Seok Seo, Corliss A. O'Bryan

Food Science Faculty Publications and Presentations

Rice supplies about 20% of the calories to the world’s consumers. Milling removes the outer husk and bran, breaking about 20% of the rice kernels during the milling process that equates to almost 100,000,000 tons of rice annually. Broken rice is discounted in price by almost half or relegated to non-human consumption. This study seeks to understand why this large percentage of rice production is discounted for human consumption. Consumers who routinely consume rice evaluated raw and cooked rice with 5%, 10%, 20%, 30% and 40% levels of brokens. Sensory analysis indicated the appearance of raw rice with high levels …

Thermoelectric-Based Cooling Systems For Building Application: A Sustainable Solution, Seyedehmohadeseh Seyednezhad

Theses and Dissertations

In the United States, buildings account for a large share of the annual energy consumption, nearly 40%. Fossil fuels including coal, oil, and natural gas account for the main source of electric power generation and constitute the largest portion of the building energy consumption. Such a high level of fossil fuel consumption is a multifaceted challenge as demand for energy grows, and natural resources become scarce and expensive, while the climatic effects of massive energy use will be clearly felt by all. As a necessary component for occupants’ thermal comfort, cooling and air conditioning systems are among the largest energy …

The Relationship Between Mindfulness, Social Anxiety Traits, And Emotions, Maria Jackeline Diaz

Theses and Dissertations

The relationship between mindfulness, social anxiety traits, and emotion processing is the first study of its kind to be looked over. In this study we will assess similarities and differences, plus how they work together to provide further research and understanding of these complexities when combined. Such research can be helpful in making us understand our emotions, as well as how our emotions can be perceived in social functioning and communication.

Teacher Knowledge, Perceptions, And Language Orientations Towards Oral Language Instruction In A Dual Language Classroom, Lucy A. Montalvo

Theses and Dissertations

Dual language (DL) schools provide literacy in students’ native languages; however, it is unknown if there is a focus on oral language (OL) development, an essential component for emergent bilinguals’(EB) literacy development. The purpose of this mixed-methods case study is to understand what DL teachers in Virginia know about OL instruction when providing literacy instruction to EB students. This study also explored DL teachers’ perceptions and language orientations towards OL instruction in a DL classroom. The Holistic Biliteracy Framework by Escamilla et al. (2014) provided a research-based pedagogical model to compare teachers’ knowledge on OL instruction. The Language Orientation Framework …

Resiliency Of Utah's Road Network: A Logit-Based Approach, Max Evan Barnes

Theses and Dissertations

The Utah Department of Transportation (UDOT) manages and maintains a complex state-wide network of highways. Recent incidents such as the collapse of the I-35W bridge in Min- neapolis, Minnesota, and the I-85/Piedmont Road fire and subsequent bridge collapse in Atlanta, Georgia, have brought identification of transportation network vulnerabilities to the forefront of UDOT’s planning efforts. Traditional estimates of transportation network impacts have focused on increases to user travel time or the volume of affected traffic, but studies of these disasters have revealed that when facing a degraded transportation network, people adjust their trip making in terms of destination, mode, and …

Roi-Aware Content-Adaptive Video Streaming System For Power Savings, William Oswald

Graduate Theses and Dissertations (2019 - present)

The demand for mobile video streams is constantly increasing. With this demand comes a need for mobile devices to receive more videos at ever increasing quality. However, due to the large size of video data and intensive computational requirements, video streaming requires frequent memory access that consumes a substantial amount of mobile device power; as a result, the battery life of mobile devices is limited. In this thesis, a video content-adaptable Region-of-Interest (ROI)-aware video storage technique that promotes power savings is presented. During the video encoding process on the transmitting server, based on the macroblock variance and ROI characterization, the …

Expanding The Concept Of Comprehensive Area Ratio Parameter To The South-Central States: Towards Simplifying The Structural Evaluation Of Flexible Pavements At The Network Level, Mena Souliman, Samer Dessouky, Nitish R. Bastola

Publications

The surface deflection bowl data collected through falling weight deflectometer (FWD) test is utilized by highway agencies in assessing the performance of the flexible pavement. However, a robust method to evaluate pavement sections utilizing FWD data from all the sensors is seldom developed. There is always a need for DOTs and highway agencies to have a simplified procedure, which can be directly implemented in agencies' databases. This study focuses on expanding and validating the concept of previously developed area ratio parameters towards the pavement section of South-Central States (Arkansas, Louisiana, New Mexico, Oklahoma, and Texas) in effectively analyzing the pavement …

Theorizing A Catholic Hispanic-Serving Institution (C-Hsi) Identity Through Latinx Theological Lenses Of Lo Cotidiano And Traditioning, Gina A. Garcia, John Decostanza Jr, Jaqueline Romo

Journal of Catholic Education

As the students entering U.S. colleges and universities become increasingly diverse, the number of Hispanic-Serving Institutions (HSI's) continues to increase. Catholic colleges and universities, similarly, are seeing an increase in student diversity on campus, with an emergence of Catholic HSIs as well. As the number of Catholic colleges and universities in the United States that are HSI-eligible increases they must grapple with what it means to be both Catholic and Hispanic-serving. The purpose of this article is to propose a U.S. Catholic HSI (C- HSI) identity that brings together the extensive literatures on Catholic identity and HSI identity through the …