Digital Commons Network^™

La Esfera Lúdica: Entretenimiento Popular En El Espacio Público Urbano Del Río De La Plata, 1870-1933, Maria Soledad Mocchi Radichi

Arts & Sciences Graduate Student Theses and Dissertations

In this dissertation, I focus on popular ludic and cultural practices that shaped the urban spaces of Uruguay and Argentina at the end of the nineteenth century and the beginning of the twentieth. I argue that by inhabiting the public sphere in close dialogue with modernization and urbanization, popular entertainment became a main protagonist within everyday life. Cultural practices such as carnival, theater, soccer, radio, and cinema, presented intersections between each other. These intersections generated what I term the ludic urban sphere, to underscore not just the overwhelming presence of play and entertainment as central elements in the urban landscape, …

Addressing Pragmatic Challenges In Utilizing Ai For Security Of Industrial Iot, Maede Zolanvari

McKelvey School of Engineering Graduate Student Theses & Dissertations

Industrial control systems (ICSs) are an essential part of every nation's critical infrastructure and have been utilized for a long time to supervise industrial machines and processes. Today’s ICSs are substantially different from the information technology (IT) devices a decade ago. The integration of internet of things (IoT) technology has made them more efficient and optimized, improved automation, and increased quality and compliance. Now, they are a sub (and arguably the most critical) part of IoT's domain, called industrial IoT (IIoT).

In the past, to secure ICSs from malicious outside attack, these systems were isolated from the outside world. However, …

“Africa Of The Heart”: The African Experience In Derek Walcott's Omeros, Hussein Kadhum Challab

Alustath Journal for Human and Social Sciences

Derek Walcott's book-length poem Omeros won critical acclaim soon after its publication in 1990. In this poem, the world of the Caribbean is linked with that of Homer by recalling the dramas of Homer’s Iliad and Odyssey in a Caribbean setting. Africa is heavily featured in Omeros as most of the major characters of the poem who in one way or another go through the African experience. 'Return to Africa' is a recurrent theme in Derek Walcott's works. However, this kind of return is not for the sole purpose of finding their old lost homeland, but rather for establishing roots …

Satirizing Empire: Comparing Ancient China And Rome, Di Wang

Arts & Sciences Graduate Student Theses and Dissertations

Comparative scholars of the ancient Mediterranean and East Asian worlds have recently taken a serious interest in the unprecedented and simultaneous emergence of two classical empires: Rome and China. The trend, invigorated by the contemporary geopolitical development of China’s rise as a world empire challenging the post-World War II Western hegemony, has yielded new insights into the many divergences and convergences of the world’s two most enduring political and cultural systems. However, preoccupied with describing the political, cultural institutions and grand narratives of empire, scholarship has largely ignored the detractors of empire, whose ingenious expressions are as enduring as these …

Informetrics Of Webinars Through Video Conferencing Platforms For Teaching And Learning By Different Lis Professional During Covid-19 Period: An Evaluative Study, Laltu Aich, Ankit Das

Library Philosophy and Practice (e-journal)

Now-a-days education and educational resources are open to all but we are facing a terrible epidemic situation due to Corona virus (COVID-19), so we need different electronic learning platforms for e-learning. In this present study, authors have explained, how many webinars are organized by Library and Information Science (LIS) professional during this period April 2020 to June 2021, distribution of webinars based on month capacity, how many web conferencing platforms used in LIS related webinars, distribution of types of organizers of webinars, distribution of webinars based on the respective region, distribution of webinars by time duration and time schedule. The …

Probing New Physics Beyond The Standard Model Via New Neutrino Interactions, Garv Chauhan

Arts & Sciences Graduate Student Theses and Dissertations

The Standard Model (SM) of Particle Physics provides a self-consistent quantum field theoretic framework to explain three of the four known fundamental forces (electromagnetic, weak, strong) along with classifying all known elementary particles. Since its conception in the 1960s, the SM has been one of the most tested theories of physics and has withstood all experimental batterings. In spite of these successes, there are compelling indications, both experimental and theoretical, that require us to expand our understanding of the nature beyond the SM (BSM). Arguably the most glaring indication of BSM physics is the observation of neutrino oscillations, which implies …

Quantifying Components Of Protein Translation And Metabolite Heterogeneity In Isogenic Microbial Populations, Alexander Schmitz

McKelvey School of Engineering Graduate Student Theses & Dissertations

Cell-to-cell variation in gene expression and metabolite levels have a significant impact on ensemble productivity of microbial bioproduction. New metabolic engineering tools and approaches are needed that consider cell cultures as an amalgam of uniquely behaving individuals to improve the slow commercialization of metabolically engineered systems. Stochastic cellular process including gene expression, metabolism, and growth lead to phenotypic variation between genetically identical cells. Understanding and the ability to control microbial phenotypic variation is key to improving microbial bioproduction metrics. During protein translation, codon usage strongly influences ensemble gene expression but the effect on the variation of gene expression was not …

A Study On The Hormonal Regulation And Novel Role Of Na+ Leak Channel, Non-Selective (Nalcn) In Human Myometrial Smooth Muscle Cells, Chinwendu Amazu

Arts & Sciences Graduate Student Theses and Dissertations

During pregnancy, the uterus transitions from a quiescent state to an excitable, highly contractile state to deliver the fetus. Two important contributors essential for this transition are progesterone (P4) and estrogen (E2), which promote quiescence or contraction, respectively, by acting on the myometrial smooth muscle cells (MSMCs). While these hormones regulate uterine contractions, it is unclear how they affect electrical activity of MSMCs, which underlies uterine contractile activity. Our lab recently identified Na+ leak channel, non-selective (NALCN) as a component of the leak current in human MSMCs and showed that mice lacking NALCN in the uterus have dysfunctional labor. In …

Characterization And Proteolytic Maturation Of Head Proteins In A Giant Salmonella Virus, Aaron Scheuch

Theses

Giant phages are of interest for biocontrol of pathogenic bacteria, however, there is limited knowledge about their biology. We study the Salmonella phage SPN3US to better understand virion structure and function. SPN3US has a contractile tail and a large T=27 icosahedral capsid that contains its 240-kb genome. Previous analyses showed the SPN3US virion is highly unusual because it contains >80 different proteins, a number that is highly unusual for a tailed phage. In addition, there is a mass (>40 MDa) of proteins ("ejection proteins") within the head that enter the Salmonella cell, possibly with roles in host takeover at …

The Artemis Project: Exploring Mass Communication Utilizing A Visual Exploration Of Influential Imagery., Brooke K. Collins

Theses

Society struggles to have difficult conversations. Polite silence is often preferred to dredging up uncomfortable topics. This silence is deafening as the majority of Americans do not consider topics such as The American Sex Trafficking Crisis. In a post-pandemic world, how do we initiate difficult conversations in both digital forums and public domains? The Artemis Project seeks to visually explore this gap in conversation, undergoing an optical investigation of utilizing design and illustrative practices as tools for mass communication. This project conceptualizes the development and application of imagery to introduce a conversation, facilitating understanding and empathy. In short, The Artemis …

Amazon Reviews Using Sentiment Analysis, Ammar Rashed Hamdallah

Theses

The intense competition to attract and maintain customers online is compelling businesses to implement novel strategies to enhance the customer experiences. It is becoming necessary for companies to examine customer reviews on online platforms such as Amazon to understand better how customers rate their products and services. The purpose of this study is to investigate how companies can conduct sentiment analysis based on Amazon reviews to gain more insights into customer experiences. The dataset selected for this capstone consists of customer reviews and ratings from consumer reviews of Amazon products. Amazon product reviews enable a business to gain insights on …

Virology: Mutagenizing The Proteolytic Cleavage Site In The Major Capsid Protein In Ssv1, Thejanee Liyanaarachchi

University Honors Theses

SSV1, spindle-shaped virus 1, is an archaeal virus with a unique shape that belongs to the family of fuselloviruses and infects hyperthermophilic archaea that thrive at 80°C and pH 3. SSV1 has two capsid proteins, VP1 and VP3, that presumably produce the lemon-shaped virion structure characteristic of fuselloviruses. The VP1 amino acid sequence is highly conserved among SSVs. Here, we investigate the importance of the proteolytic cleavage site in position E66 in VP1 by changing its glutamic acid to the other 19 amino acids. We have developed a new protocol for creating SSV1 mutants through HiFi Assembly (NEB) to increase …

An Investigation Into The Relationship Between Obstetric Racism And Postpartum Depression In Black Women, Miguel A. Claxton Iii

University Honors Theses

Postpartum depression is the most common postpartum mood disorder, with 13% of new mothers reporting symptoms within the first year. Adverse birth outcomes, such as low birth weight and preterm birth co-index with the development of postpartum depression. This correlation is particularly alarming considering that Black women have about a 60% higher rate of preterm birth and an 88% higher rate of low birth weight infants than Caucasian women. By utilizing theories of stratified reproduction, necropolitics, and obstetric racism, this paper aims to situate postpartum depression in Black women as a psychological response to systems of medicolegal control and domination. …

Psychological Assessment And Testing, Leslie A. Miller, Ruby Daniels

Marketing Faculty Publications (Archived)

No abstract provided.

The Effect Of Promotion On Instagram With Psychographics On The Intensity Of Visits At The Ministry Library In Indonesia, Tri Hartanto, Muhammad Azwar

Library Philosophy and Practice (e-journal)

Libraries have an essential role in managing collections to meet the information needs of users. Libraries need to do more intense promotions by optimizing Instagram's social media. This study aims to determine how much influence promotion on Instagram with psychographics has on the Intensity of visits at the ministry library in Indonesia. This research was conducted in the library of the ministry of education and culture, Indonesia. This study uses associative statistics with a quantitative approach. The data analysis used was multiple linear regression to test the hypothesis of the influence of variables X1 and X2 on variable Y. Sampling …

Transcriptional Reprogramming Differentiates Active From Inactive Esr1 Fusions In Endocrine Therapy-Refractory Metastatic Breast Cancer, Xuxu Gou, Shunqiang Li, Et Al.

2020-Current year OA Pubs

Genomic analysis has recently identified multiple

The Impact Of The Rare Disease And Orphan Drug Act In Taiwan, Ning-Chun Hsiang, Weng-Foung Huang, Churn-Shiouh Gau, Teng-Wen Tsai, Lin-Chau Chang

Journal of Food and Drug Analysis

The Rare Disease and Orphan Drug Act (the Act) was enacted in 2000 in Taiwan for the facilitation of the research, development, and accessibility of orphan drugs and special nutritional foods; for the prevention and early diagnosis of rare diseases; and for providing intensive care for patients with rare diseases. The aim was to investigate the impact of the Act on the availability and use of orphan drugs in Taiwan in the hope of identifying the remaining challenges and possible solutions to assist future policy making, which may be applicable in other countries as well. The information and statistics for …

A Novel Nrf2/Are Inhibitor Gossypol Induces Cytotoxicity And Sensitizes Chemotherapy Responses In Chemo-Refractory Cancer Cells, Ya-Chu Tang, Hsin-Huei Chang, Huang-Hui Chen, Jau-Ying Yao, Yu-Tsen Chen, Yung-Jen Chuang, Jang-Yang Chang, Ching-Chuan Kuo

Journal of Food and Drug Analysis

NRF2/ARE signaling pathway is a principal regulator of cellular redox homoeostasis. The stress-induced transcription factor, NRF2, can shield cells from the oxidative damages via binding to the consensus antioxidant-responsive element (ARE) and driving several cyto-protective genes expression. Increasing evidence indicated that aberrant activation of NRF2 in malignant cells may support their survival through various pathways to detoxify chemotherapy drugs, attenuate drug-induced oxidative stress, or induce drug efflux, all of which are crucial in developing drug resistance. Accordingly, NRF2 is a potential drug target for improving the effectiveness of chemotherapy and to reverse drug resistance in cancer cells. A stable ARE-driven …

Curcumin-Induced Antitumor Effects On Triple-Negative Breast Cancer Patient-Derived Xenograft Tumor Mice Through Inhibiting Salt-Induced Kinase-3 Protein, Tzu-Chun Cheng, John Oliver Sayseng, Shih-Hsin Tu, Ting-Ching Juan, Chia-Lang Fang, You-Cheng Liao, Cheng-Ying Chu, Hui-Wen Chang, Yun Yen, Li-Ching Chen, Yuan-Soon Ho

Journal of Food and Drug Analysis

This study demonstrated for the first time that curcumin effectively inhibits the growth of triple-negative breast cancer (TNBC) tumors by inhibiting the expression of salt-induced kinase-3 (SIK3) protein in patient-derived xenografted tumor mice (TNBC-PDX). For TNBC patients, chemotherapy is the only option for postoperative adjuvant treatment. In this study, we detected the SIK3 mRNA expression in paired-breast cancer tissues by PCR analysis. The results revealed that SIK3 mRNA expression was significantly higher in tumor tissues when compared to the normal adjacent tissues (73.25 times, n=183). Thus, it is proposed for the first time that the antitumor effect induced by curcumin …

Exile Talks To Reginald Mcknight, Paul Durica, Alison Stine

Exile

No abstract provided.

Changing Face Of Jacksonville, Florida: 1900-1910, James B. Crooks

Florida Historical Quarterly

Compelled by a devastating fire, May 3, 1901, that laid waste to most of downtown, Jacksonville not only rebuilt, but changed notably in other ways during the first decade of the twentieth century. Its population more than doubled. New or expanding suburbs, skyscrapers, hotels, theaters, automobiles, streetcar lines, parks, and city services reflected urban development. Substantial economic growth took place in banking, trade, and transportation. Public and private efforts to provide health, education, and human services increased. In addition, the community’s popular culture became more diversified.

Partnerships And Collaboration: Working Together To Build And Achieve Disaster Recovery, Joseph Richmond, Cheryl Knight

Journal of Global Awareness

On May 22, 2011, an EF-5 tornado struck Joplin, Missouri, leaving behind 161 fatalities and $2.8 billion in economic impacts. This case study research design used in-depth semi-structured, one-on-one interviews and a qualitative design and analysis to examine the economic recovery following the disaster. It also formed the foundation for future research on the impact of interdisciplinary teams, specifically disaster emergency management and social work in disaster recovery.

Lessons Learned From Bp: Deepwater Horizon And The Transition To Renewables, Daniel Valle

Journal of Global Awareness

This paper analyzes the gradual transition of British Petroleum (BP), one of the world's largest oil and gas companies, into a renewable energy company focused on sustainability and the reduction of carbon emissions. BP's leadership and ethical practices are compared before and after the 2010 Deepwater Horizon disaster. The purpose of the comparison and the broader analysis of the transition is to identify how effective leadership can be used to transform a company with a suspect social responsibility record into a leader among its peers. Lessons learned from the disaster, and the subsequent transition conclude the research.

Stakeholder Involvement In Upscaling Of Soil Fertility Research Output In Tharaka-Nithi County, Kenya, Serah W. Kimaru-Muchai

Journal of Global Awareness

Food insecurity in Sub-Saharan Africa has prompted a lot of research in the development of soil fertility technologies; however, few of the recommendations from soil fertility management research have been put into use by the target end-users. The objective of the study was to investigate information exchange pathways used by researchers in upscaling of soil fertility in Maara and Mbeere South Sub-counties in Kenya. Structured questionnaires were used to collect information from 22 researchers and 240 farmers. Data was analyzed using descriptive statistics like frequency, mean, and percentages, while Chi-square, Kendal's correlation coefficient was used to test the magnitude of …

We Hold These Distruths To Be Self-Evident: How Legal History Could Save America From Itself, William Murphy

Journal of Global Awareness

This paper explores the threat of disinformation to American society. Focusing on social and cable news media as the primary disseminators of disinformation, it examines how the very design and nature of these two mediums promote and stimulate the intentional and viral spread of wholly inaccurate information as well as the significant and tangible negative consequences experienced across American society as a result. The paper subsequently proposes a legal solution to this dilemma in the form of a repeal of Section 230 paired with a reinstatement of the Fairness Doctrine. The background, history, and effect of each are thoroughly discussed, …

Notes From The Editor, Jay Nathan

Journal of Global Awareness

No abstract provided.

Adjusting Equalizer Settings Based On Learned User Preferences, Michael D. Townsend

Defensive Publications Series

Currently, the equalizer settings for media playback via a headset are selected based on a limited number of user studies. Equalizer preferences depend on various factors, including earbud fit (which impacts audio leakage levels) and the genre of audio being listened to. This disclosure describes techniques to automatically set or recommend equalizer settings using machine learning models that are trained on a crowdsourced dataset of user preferences, obtained with user permission. Equalizer settings, audio genre, and magnitude of acoustic leakage are obtained from deployed media playback devices and are used to train the machine learning model. During operation, the trained …

Teaching And Assessing College Stem Courses Online During Covid-19: Evidence-Based Strategies And Recommendations, Santanu De, Georgina Arguello

FDLA Journal

Since the devastating COVID-19 pandemic, most schools, colleges, and universities worldwide underwent a paradigm shift by transitioning to digital teaching and learning modalities. This phenomenon was essential to mitigate the contagion; however, the academic institutions needed to quickly come up with ways to ensure that the quality and rigor of education were maintained, especially the active and experiential learning required by undergraduate and graduate courses in science, technology, engineering, and mathematics (STEM). This paper highlights key approaches reported or proposed to effectively conduct college-level, in-person STEM courses online owing to the pandemic. These would range from synchronous versus asynchronous pedagogies …

A Study On The Impact Of Socioeconomic Status On Emergency Electronic Learning During The Coronavirus Lockdown, Marie Camille Cuisia-Villanueva, Jayrome Lleva Núñez

FDLA Journal

This research paper tackles the relationship of socioeconomic status (SES) to students’ emergency electronic learning (e-Learning) during the Coronavirus (COVID-19) lockdown period in the Philippines. The study investigates the impact of accessibility to the students’ performance in distance learning. By looking at these variables, the researchers seek to answer the research question, ‘what is the impact of the students’ family socioeconomic status on their accessibility to emergency e-Learning’. This mini-study will be viewed in the lens of human capital theory guided by Gary Becker (1964).

Philosophical Foundations Of African Women's Indigenous Knowledge For Food Security: Towards Narrative Feminist Pedagogy, Humphrey Jeremiah Ojwang, Wanjiku Mukabi Kabira, Penninah Amolo Ogada

FDLA Journal

This paper explores the pedagogical value of African Women’s Indigenous Knowledge or Food Security. The approach is narratological and takes into account oral testimonies and life-stories of women farmers in Homa Bay County, Kenya. The paper proposes African feminist epistemology as a viable approach in the pedagogy of food security and agricultural extension in rural Kenya. This is a paradigm shift which incorporates women farmers’ indigenous knowledge in formal agricultural education and extension programmes. The paradigm shift to African feminist epistemology is a response to a pedagogical anomaly where women’s indigenous knowledge has been relegated to the sidelines, with hegemonic …