Digital Commons Network^™

How Is Organisational Fit Addressed In Australian Entry Level Midwifery Job Advertisements, Dianne Bloxsome, Courtney Glass, Sara Bayes

Research outputs 2014 to 2021

Background: Midwifery job retention is an ongoing global issue. Prior research has recognised that considering an individual’s attributes in relation to their work environment may assist in improving job satisfaction among midwives, leading to improved long-term job retention in the midwifery profession. The aim of this study was to evaluate whether, and how organisational fit is addressed in current entry level midwifery job advertisements within Australia. Methods: Midwifery jobs were searched for within 12 search engines, using the search term ‘midwife’, including Seek.com, Indeed.com, government employment websites for all Australian states and territories, and private health organisation websites. Data were …

Process Development And Safety Evaluation Of Abcb5+ Limbal Stem Cells As Advanced-Therapy Medicinal Product To Treat Limbal Stem Cell Deficiency, Alexandra Norrick, Jasmina Esterlechner, Elke Niebergall-Roth, Ulf Dehio, Samar Sadeghi, Hannes M. Schröder, Seda Ballikaya, Nicole Stemler, Christoph Ganss, Kathrin Dieter, Ann-Kathrin Dachtler, Patrick Merz, Saadettin Sel, James Chodosh, Claus Cursiefen, Natasha Y. Frank, Gerd U. Auffarth, Bruce Ksander, Markus H. Frank, Mark A. Kluth

Research outputs 2014 to 2021

Background: While therapeutic success of the limbal tissue or cell transplantation to treat severe cases of limbal stem cell (LSC) deficiency (LSCD) strongly depends on the percentage of LSCs within the transplanted cells, prospective LSC enrichment has been hampered by the intranuclear localization of the previously reported LSC marker p63. The recent identification of the ATP-binding cassette transporter ABCB5 as a plasma membrane-spanning marker of LSCs that are capable of restoring the cornea and the development of an antibody directed against an extracellular loop of the ABCB5 molecule stimulated us to develop a novel treatment strategy based on the utilization …

An Integrative Literature Review Of The Implementation Of Microcredentials In Higher Education: Implications For Practice In Australasia, Ratna M. Selvaratnam, Michael D. Sankey

Research outputs 2014 to 2021

Micro-credentials research, which includes digital badges, is a relatively new field of study that seeks to inform the implementation, portability and sustainability of the ecology of meaningful delivery. This paper reviews literature relevant to understanding connections between universities' intent to offer micro-credentials and the environment that is needed to do so. From this integrated study, the paper distils a number of core concerns and identifies some gaps in the literature. One of its primary goals is to clear the ground for the construction of a technical model of micro-credentialing implementation that can be used by the various stakeholders involved in …

Development Of A Breech-Specific Integrated Care Pathway For Pregnant Women: Protocol For A Mixed Methods Study, Sara Morris, Sadie Geraghty, Deborah Sundin

Research outputs 2014 to 2021

Background: The development of an integrated care pathway with multidisciplinary input to standardize and streamline care for pregnant women experiencing breech presentation at 36 or more weeks of gestation poses several challenges because of the divisive and contentious nature of the phenomenon. Although many clinicians are interested in obtaining the skills required to safely support women desiring a vaginal breech birth, the primary trend in most health care facilities is to recommend a cesarean section. Objective: This paper aims to discuss the mixed methods approach used in a doctoral study conducted to generate new knowledge regarding women’s experiences of breech …

Detect Schools Study Protocol: A Prospective Observational Cohort Surveillance Study Investigating The Impact Of Covid-19 In Western Australian Schools, Marianne J. Mullane, Hannah M. Thomas, Melanie Epstein, Joelie Mandzufas, Narelle Mullan, Alexandra Whelan, Karen Lombardi, Tina Barrow, Sherlynn Ang, Adele Leahy, Ewan Cameron, Leanne Lester, Matt Cooper, Paul Stevenson, Mitch Hartman, Anne Mckenzie, Francis Mitrou, Stephen R. Zubrick, Juli Coffin, Donna Cross, Asha C. Bowen, Peter Gething

Research outputs 2014 to 2021

Introduction: Amidst the evolving COVID-19 pandemic, understanding the transmission dynamics of the SARS-CoV-2 virus is key to providing peace of mind for the community and informing policy-making decisions. While available data suggest that school-aged children are not significant spreaders of SARS-CoV-2, the possibility of transmission in schools remains an ongoing concern, especially among an aging teaching workforce. Even in low-prevalence settings, communities must balance the potential risk of transmission with the need for students' ongoing education. Through the roll out of high-throughput school-based SARS-CoV-2 testing, enhanced follow-up for individuals exposed to COVID-19 and wellbeing surveys, this study investigates the dynamics …

Self-Regulatory Goal Motivational Processes In Sustained New Year Resolution Pursuit And Mental Wellbeing, Joanne M. Dickson, Nicholas J. Moberly, David Preece, Alyson Dodd, Christopher D. Huntley

Research outputs 2014 to 2021

Recent research suggests people typically “give up” pursuing their New Year resolutions within the first month. The present study investigated goal features proposed to be implicated in promoting both mental wellbeing and sustained New Year resolution pursuit. Australian and UK participants (n = 182) took part in an online longitudinal study, including four timepoints over a two-month period. At baseline, participants listed the New Year resolution to which they were most committed, and completed self-report measures to assess mental wellbeing, goal flexibility and te-nacity. At the follow-up surveys, participants completed the wellbeing measure and their New Year resolution commitment, effort …

Plasma Amyloid‐Beta Levels In A Pre‐Symptomatic Dutch‐Type Hereditary Cerebral Amyloid Angiopathy Pedigree: A Cross‐Sectional And Longitudinal Investigation, Pratishtha Chatterjee, Michelle Tegg, Steve Pedrini, Anne M. Fagan, Chengjie Xiong, Abhay K. Singh, Kevin Taddei, Samantha Gardener, Colin L. Masters, Peter R. Schofield, Gerhard Multhaup, Tammie L. S. Benzinger, John C. Morris, Randall J. Bateman, Steven M. Greenberg, Mark A. Van Buchem, Erik Stoops, Hugo Vanderstichele, Charlotte E. Teunissen, Graeme J. Hankey, Marieke J. H. Wermer, Hamid R. Sohrabi, Ralph N. Martins, The Dominantly Inherited Alzheimer Network

Research outputs 2014 to 2021

Plasma amyloid‐beta (Aβ) has long been investigated as a blood biomarker candidate for Cerebral Amyloid Angiopathy (CAA), however previous findings have been inconsistent which could be attributed to the use of less sensitive assays. This study investigates plasma Aβ alterations between pre‐symptomatic Dutch‐type hereditary CAA (D‐CAA) mutation‐carriers (MC) and non-carriers (NC) using two Aβ measurement platforms. Seventeen pre‐symptomatic members of a D‐ CAA pedigree were assembled and followed up 3–4 years later (NC = 8;MC = 9). Plasma Aβ1‐40 and Aβ1‐42 were cross‐sectionally and longitudinally analysed at baseline (T1) and follow‐up (T2) and were found to be lower in MCs …

Deconstructing Health And Physical Education Teacher Education: A Mapping And Analysis Of Programme Structure And Content In Australia, Donna Barwood, Lachlan T. Spears, Eibhlish O'Hara, Dawn Penney

Research outputs 2014 to 2021

Background: In Australia, Initial Teacher Education Institutions (ITEIs) provide undergraduate Health and Physical (HPE) programmes that meet a number of regulatory requirements, including those of the Australian Institute for Teaching and School Leadership (AITSL) and the Tertiary Education Quality and Standards Agency (TEQSA). In addition, ITEIs must also ensure programme alignment with state/territory-based jurisdictional requirements. While historically varied philosophies and practices have shaped HPE teacher education nationally, ITEIs are thus operating in an increasingly regulated environment.

Purpose: The purpose of this paper is to report research that has critically examined the structure and content of ITEI undergraduate programmes …

Risks To Healthcare Organizations And Staff Who Manage Obese (Bariatric) Patients And Use Of Obesity Data To Mitigate Risks: A Literature Review, Kim Mcclean, Martyn Cross, Sue Reed

Research outputs 2014 to 2021

This literature review explores obesity risks to healthcare staff and organizations that manage and caring for obese (bariatric) patients. These risks are anticipated to increase due to Australian population obesity rate projections increasing from 31% in 2018 to 42% by the year 2035, which will result in increased hospital admissions of patients with obesity. Literature searches were conducted through the Cumulative Index to Nursing and Allied Health Literature (CINAHL), MEDLINE, Scopus, and Web of Science. Thirty studies met the inclusion criteria and were tabulated and critiqued using appropriate appraisal techniques. High risk of injury to healthcare staff was identified relating …

Reliability Of Isokinetic Tests Of Velocity‐ And Contraction Intensity‐Dependent Plantar Flexor Mechanical Properties, Matheus D. Pinto, Cody J. Wilson, Anthony D. Kay, Anthony J. Blazevich

Research outputs 2014 to 2021

“Flexibility” tests are traditionally performed voluntarily relaxed by rotating a joint slowly; however, functional activities are performed rapidly with voluntary/reflexive muscle activity. Here, we describe the reliabilities and differences in maximum ankle range of motion (ROM_max) and plantar flexor mechanical properties at several velocities and levels of voluntary force from a new test protocol on a commercially available dynamometer. Fifteen participants had their ankle joint dorsiflexed at 5, 30, and 60° s⁻¹ in two conditions: voluntarily relaxed and while producing 40% and 60% of maximal eccentric torque. Commonly reported variables describing ROM_max and resistance to stretch …

Forensic Experts’ Perspectives On Australian Indigenous Sexual Offenders And Factors Important In Evaluating The Risk Of Recidivism, Alfred Allan, Cate L. Parry, Hilde Tubex, Caroline Spiranovic, Frank Morgan

Research outputs 2014 to 2021

Law and ethics require that risk assessment should be cross-culturally valid and fair, but Australian research in this regard is underdeveloped. A logical first step in progressing the work required to build a strong evidence base on culturally sensitive risk assessment in Australia is to determine the expert views of those in the field. We interviewed 13 Australian evaluators who assess Indigenous sexual offenders’ recidivism risk to determine their perceptions of the risk assessment instruments they use and the attributes they believe evaluators doing cross-cultural assessments should have. Our central findings are that evaluators use the available instruments because they …

Foot Ulcers Associated With External Trauma Among People With Diabetes: An Integrative Review Of The Origin Of Trauma And Outcomes, Ma-En Zaid Abu-Qamar, Vivien Kemp, Lisa Whitehead

Research outputs 2014 to 2021

Background

Foot ulcers are common among people with diabetes. These ulcers are caused by a number of factors including trauma. To date, research findings on the origin of external trauma and the outcome of foot ulcers resulting from an external trauma have not been summarised.

Objective

To examine the origin of external trauma that contribute to the development of foot ulcers among people with diabetes and the outcome of such ulcers.

Design

An integrative review.

Settings

Hospital/community.

Participants

Patients with diabetes and foot ulcer.

Method

The Joanna Briggs framework was used to underpin this integrative review. Six different databases (CINAHL …

Towards Predicting Dnapl Source Zone Formation To Improve Plume Assessment: Using Robust Laboratory And Numerical Experiments To Evaluate The Relevance Of Retention Curve Characteristics, Christian Engelmann, Kaveh Sookhak Lari, Luisa Schmidt, Charles J. Werth, Marc Walther

Research outputs 2014 to 2021

© 2020 The Authors We conducted multiple laboratory trials in a robust and repeatable experimental layout to study dense non-aqueous phase liquid (DNAPL) source zone formation. We extended an image processing and analysis framework to derive DNAPL saturation distributions from reflective optical imaging data, with volume balance deviations < 5.07%. We used a multiphase flow model to simulate source zone formation in a Monte Carlo approach, where the parameter space was defined by the variation of retention curve parameters. Integral and geometric measures were used to characterize the source zones and implemented into a multi-criteria objective function. The latter showed good agreement between observation data and simulation results for effective DNAPL saturation values > 0.04, especially for early stages of DNAPL migration. The common hypothesis that parameters defining the DNAPL-water retention curves are constant over time was not confirmed. Once DNAPL pooling started, the optimal fit in the parameter space was significantly different compared to the earlier DNAPL migration stages. We suspect more complex processes (e.g., …

Mental Health Consequences Of Covid-19 Media Coverage: The Need For Effective Crisis Communication Practices, Zhaohui Su, Dean Mcdonnell, Jun Wen, Metin Kozak, Jaffar Abbas, Sabina Šegalo, Xiaoshan Li, Junaid Ahmad, Ali Cheshmehzangi, Yuyang Cai, Ling Yang, Yu Tao Xiang

Research outputs 2014 to 2021

© 2021, The Author(s). During global pandemics, such as coronavirus disease 2019 (COVID-19), crisis communication is indispensable in dispelling fears, uncertainty, and unifying individuals worldwide in a collective fight against health threats. Inadequate crisis communication can bring dire personal and economic consequences. Mounting research shows that seemingly endless newsfeeds related to COVID-19 infection and death rates could considerably increase the risk of mental health problems. Unfortunately, media reports that include infodemics regarding the influence of COVID-19 on mental health may be a source of the adverse psychological effects on individuals. Owing partially to insufficient crisis communication practices, media and news …

Comparison Of Circulating Tumour Dna And Extracellular Vesicle Dna By Low-Pass Whole-Genome Sequencing Reveals Molecular Drivers Of Disease In A Breast Cancer Patient, Olivia Ruhen, Bob Mirzai, Michael E. Clark, Bella Nguyen, Carlos Salomon, Wendy Erber, Katie Meehan

Research outputs 2014 to 2021

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. There is increasing recognition of circulating tumour DNA (ctDNA) as a non-invasive alternative to tumour tissue for the molecular characterisation and monitoring of disease. Recent evidence suggests that cancer-associated changes can also be detected in the DNA contained within extracellular vesicles (EVs). As yet, there has been limited investigation into the relationship between EV DNA and ctDNA, and no studies have examined the EV DNA of breast cancer patients. The aim of this study was to use low-pass whole-genome sequencing to identify copy number variants (CNVs) in serial samples of both …

Titanium Nitride Thin Film Based Low‐Redox‐Interference Potentiometric Ph Sensing Electrodes, Shimrith Paul Shylendra, Wade Lonsdale, Magdalena Wajrak, Mohammad Nur‐E‐Alam, Kamal Alameh

Research outputs 2014 to 2021

© 2020 by the authors. Licensee MDPI, Basel, Switzerland.

In this work, a solid‐state potentiometric pH sensor is designed by incorporating a thin film of Radio Frequency Magnetron Sputtered (RFMS) Titanium Nitride (TiN) working electrode and a commercial Ag|AgCl|KCl double junction reference electrode. The sensor shows a linear pH slope of −59.1 mV/pH, R2 = 0.9997, a hysteresis as low as 1.2 mV, and drift below 3.9 mV/hr. In addition, the redox interference performance of TiN electrodes is compared with that of Iridium Oxide (IrO2) counterparts. Experimental results show −32mV potential shift (E0 value) in 1 mM ascorbic acid (reducing …

Information, Communication, Advocacy, And Complaint: How The Spouse Of A Man With Aphasia Managed His Discharge From Hospital, Deborah Hersh, Elizabeth Armstrong

Research outputs 2014 to 2021

Background:

The impact of stroke and aphasia has been recognised as a family problem for many years with studies highlighting spouses’ need for information at different times along the recovery journey, for practical and emotional support, recognition, and respite. In particular, the decision-making around discharge from hospital, or planning for rehabilitation, is not always collaborative even though family involvement assists family members to plan and adjust to their new caring role.

Aims:

This study aims to explore how the wife of a man with aphasia managed his discharge from hospital in the acute phase post-stroke. It provides an opportunity for …

An Exploration Of Aphasia Therapy Dosage In The First Six Months Of Stroke Recovery, Emily Brogan, Natalie Ciccone, Erin Godecke

Research outputs 2014 to 2021

Aphasia research uses the length of time within rehabilitation sessions as the main measure of dosage. Few papers detail therapeutic ingredients or outline the number of times these were delivered over the treatment period. The present observational study identified therapeutic ingredients in the Very Early Rehabiltiation in SpEech (VERSE) trial and explored the dosage provided using a model of cumulative intervention intensity (CII). Therapists video recorded one therapy session per week and 53 (12%) randomly selected therapy videos were analysed. The videos were coded for number of error productions, self-corrections and type and frequency of therapist cueing. The Western Aphasia …

Young Adults With High Autistic-Like Traits Displayed Lower Food Variety And Diet Quality In Childhood, Catherine Panossian, Philippa Lyons-Wall, Andrew Whitehouse, Wendy H. Oddy, Johnny Lo, Jane Scott, Therese O'Sullivan

Research outputs 2014 to 2021

This study explored the association between autistic-like traits in young adults and dietary intake in early childhood in the Gen2 Raine Study cohort. Data were available from 811 participants at years 1, 2 and 3 for the assessment of dietary intake, and at year 20 for measurement of autistic-like traits. Results showed as autistic-like traits increased, total food variety, core food variety and dairy variety decreased (p < 0.05), with a lower consumption of citrus fruits and yoghurt (both p = 0.04). As autistic-like traits increased, diet quality decreased, this trend was significant at 2 years (p = 0.024). Our results suggest that young adults with higher autistic-like traits were more likely to have had lower food variety and diet quality in early childhood.

Cruciferous Vegetable Intake Is Inversely Associated With Extensive Abdominal Aortic Calcification In Elderly Women: A Cross-Sectional Study, Lauren C. Blekkenhorst, Marc Sim, Simone Radavelli Bagatini, Nicola P. Bondonno, Catherine P. Bondonno, Amanda Devine, John T. Schousboe, Wai H. Lim, Douglas P. Kiel, Richard J. Woodman, Jonathan M. Hodgson, Richard L. Prince, Joshua Lewis

Research outputs 2014 to 2021

We have previously shown higher intake of cruciferous vegetables is inversely associated with carotid artery intima-media thickness. To further test the hypothesis that an increased consumption of cruciferous vegetables is associated with reduced indicators of structural vascular disease in other areas of the vascular tree, we aimed to investigate the cross-sectional association between cruciferous vegetable intake and extensive calcification in the abdominal aorta. Dietary intake was assessed, using a food frequency questionnaire, in 684 older women from the Calcium Intake Fracture Outcome Study. Cruciferous vegetables included cabbage, Brussels sprouts, cauliflower and broccoli. Abdominal aortic calcification (AAC) was scored using the …

Taking The Pulse Of A New Football Franchise': Team Identification And The Melbourne Heart Fc In Australia's A-League, Anthony K. Kerr, Aaron J. Wijeratne

Research outputs 2014 to 2021

In a bid to revive soccer’s fortunes in Australia, the A-League was created whereby private franchises represented the country’s major cities. This article examines the Melbourne Heart FC and the emotional attachment of members during its first two seasons. A survey methodology was used to identify attitudes towards the brand and the Sport Spectator Identification Scale (SSIS) measured their identification with the franchise. There is conclusive evidence that strong levels of identification can develop quickly for a new team, yet three of the scale’s items made a weaker contribution. There is also a suggestion that identity is multi-layered. New sport …

Emergencies Within Hospital Wards: An Observational Study Of The Non-Technical Skills Of Medical Emergency Teams, Rosemary Saunders, Emma Wood, Adam Coleman, Karen Gullick, Renee Graham, Karla Seamon

Research outputs 2014 to 2021

Background

Medical emergency teams are essential in responding to acute deterioration of patients in hospitals, requiring both clinical and non-technical skills. This study aims to assess the non-technical skills of medical emergency teams during hospital ward emergencies and explore team members perceptions and experiences of the use non-technical skills during medical emergencies.

Methods

A multi-methods study was conducted in two phases. During phase one observation and assessment of non-technical skills used in medical emergencies using the Team Emergency Assessment Measure (TEAM™) was conducted; and in the phase two in-depth interviews were undertaken with medical emergency team members.

Results

Based on …

Investigating Primary Preservice Teachers’ Ultraviolet Radiation Awareness And Perceived Ability To Teach Sun Safety, Joseph Scott, Robyn Johnston, Mark Strickland, Jill Darby, Elin Gray

Research outputs 2014 to 2021

Issue addressed

Sun protection practices in Australian primary schools remain inconsistent. Therefore, this study investigates primary PSTs sun protective sun behaviours, ultraviolet (UV) radiation awareness and perceived ability to teach sun safety.

Methods

A convenience sample of undergraduate PSTs (N = 275; mean age = 23.13 years) enrolled at one Western Australian university completed an online survey. Descriptive analyses provided features of the data. Factors associated with sun protection behaviours and perceived knowledge and skill to teach sun safety were explored using multivariable logistic regression models.

Results

Lesser than 10% of participants reported using sun protective measures daily (midday shade …

Educators’ Emotions Involved In The Transition To Online Teaching In Higher Education, Dawn Naylor, Julie Nyanjom

Research outputs 2014 to 2021

Higher education (HE) has seen a growing trend towards online study. However, teaching is deeply connected to one’s beliefs, values, commitments and to relationships with students. A change in the mode of instruction and pedagogy has the potential to disrupt these deep and personal connections giving rise to an emotional response. The purpose of this phenomenological study was to explore the nature and significance of emotions in HE educators transitioning to online teaching. Findings indicate a dynamic relationship between the type of emotional responses and the amount of institutional support. Based on the type of emotional response and amount of …

Resistance Exercise Dosage In Men With Prostate Cancer: Systematic Review, Meta-Analysis And Meta-Regression, Pedro Lopez, Dennis R. Taaffe, Robert U. Newton, Daniel A. Galvao

Research outputs 2014 to 2021

Purpose

Resistance training (RT) improves an array of treatment-related adverse effects in men with prostate cancer, however, the minimal dosage required is unknown. We systematically reviewed the RT effects in prostate cancer patients to determine the minimal dosage regarding the exercise components (type, duration, volume, and intensity) on body composition, physical function, muscle strength, cardiorespiratory fitness, body mass index (BMI), and prostate-specific antigen (PSA).

Methods

Using PRISMA guidelines, MEDLINE, CINAHL, EMBASE, SPORTDiscus, and Web of Science databases were searched. Eligible randomised controlled trials examined prostate cancer patients undertaking resistance-based exercise programs during or following treatment. Meta-analysis was undertaken when more …

Comparing The Protective Effects Of Resveratrol, Curcumin And Sulforaphane Against Lps/Ifn-Γ-Mediated Inflammation In Doxorubicin-Treated Macrophages, Eman Ramadan, Mohey Elmazar, Haidy A. Saleh

Pharmacy

Doxorubicin (DOX) chemotherapy is associated with the release of inflammatory cytokines from macrophages. This has been suggested to be, in part, due to DOX-mediated leakage of endotoxins from gut microflora, which activate Toll-like receptor 4 (TLR4) signaling in macrophages, causing severe inflammation. However, the direct function of DOX on macrophages is still unknown. In the present study, we tested the hypothesis that DOX alone is incapable of stimulating inflammatory response in macrophages. Then, we compared the anti-inflammatory effects of curcumin (CUR), resveratrol (RES) and sulforaphane (SFN) against lipopolysaccharide/interferon-gamma (LPS/IFN-γ)-mediated inflammation in the absence or presence of DOX. For this purpose, …

Novel Mechanistic Insights Towards The Repositioning Of Alogliptin In Parkinson's Disease, Eman Ramadan, Marwa M. Safar

Pharmacy

Parkinson's disease (PD) is a progressive neurodegenerative disease that impairs people's lives tremendously. The development of innovative treatment modalities for PD is a significant unmet medical need. The critical function of glucagon-like peptide-1 (GLP-1) in neurodegenerative diseases has raised impetus in investigating the repositioning of a dipeptidyl peptidase IV inhibitor, alogliptin (ALO), as an effective treatment for PD. As a result, the focus of this research was to assess the effect of ALO in a rat rotenone (ROT) model of PD. For 21 days, ROT (1.5 mg/kg) was delivered subcutaneously every other day. ALO (30 mg/kg/day), delivered by gavage for …

Interpretable, Not Black-Box, Artificial Intelligence Should Be Used For Embryo Selection, Michael Anis Mihdi Afnan, Yanhe Liu, Vincent Conitzer, Cynthia Rudin, Abhishek Mishra, Julian Savulescu, Masoud Afnan

Research outputs 2014 to 2021

Artificial intelligence (AI) techniques are starting to be used in IVF, in particular for selecting which embryos to transfer to the woman. AI has the potential to process complex data sets, to be better at identifying subtle but important patterns, and to be more objective than humans when evaluating embryos. However, a current review of the literature shows much work is still needed before AI can be ethically implemented for this purpose. No randomized controlled trials (RCTs) have been published, and the efficacy studies which exist demonstrate that algorithms can broadly differentiate well between ‘good-’ and ‘poor-’ quality embryos but …

Realization And Optimization Of Optical Logic Gates Using Bias Assisted Carrier-Injected Triple Parallel Microring Resonators, Fayza Kizhakkakath, Sooraj Ravindran, Kwangwook Park, Kamal Alameh, Yong Tak Lee

Research outputs 2014 to 2021

We propose a p-i-n diode embedded parallel triple microring resonator (MRR) configuration to simultaneously realize optical OR and AND, or NAND and NOR logic gates using a bias-assisted carrier injection mechanism. The applied bias on the rings induces refractive index change in the intrinsic region through bandfilling, bandgap shrinkage and free carrier absorption effects, leading to intensity variation at the output ports of the MRR due to respective resonant wavelength shift. The optical logic gate operational outputs are represented as the light intensities at the output ports of the MRR with the wavelength of the input optical signal launched into …

Sansevieria: An Evaluation Of Potential Cytotoxic Activity In Reference To Metabolomic And Molecular Docking Studies, Amgad Albohy

Pharmacy

Sansevieria trifasciata Prain. and Sansevieria suffruticosa N.E.Br. were selected to evaluate their cytotoxic activity against colon (CACO2), lung (A-549) and liver (HepG-2) carcinoma cell lines. Results indicated that S. suffruticosa N.E.Br. showed a significant cytotoxic effect on CACO2 with IC50= 30.9 ± 0.72 μg/ml. Evaluating the phenolic and flavonoid contents, S. suffruticosa N.E.Br. has higher total phenolic and flavonoid contents than S. trifasciata Prain. The phenolic content was estimated using HPLC detecting the presence of apigenin-7-glucoside and cinnamic acid only in S. suffruticosa N.E.Br. with p-hydroxybenzoic acid and p-coumaric acid being the major compounds. While, catechin and kaempferol are the …