Digital Commons Network^™

Effects Of A Professional Development Training Package On Nature-Based Teaching Strategies For Early Childhood Educators Of Children With Developmental Disabilities, Sylvia Collazo

Electronic Theses and Dissertations 2020 - Present

Research suggests spending time outdoors and with natural materials can benefit all young children across different areas of development. However, children with developmental disabilities often have fewer opportunities to engage with nature as a result of the limited understanding and negative views about nature expressed by their caregivers and educators. This study examined the effects of a professional development training package on the knowledge, perception, and application of nature-based teaching strategies of early childhood educators who teach young children with developmental disabilities. It also explored how teachers’ implementation of nature-based activities support children’s developmental outcomes. Results showed the professional development …

Effects Of Serotonin Modulation On Methionine Sulfoxide Reductase Deficient Drosophila Melanogaster, Ali Hamadeh

Electronic Theses and Dissertations 2020 - Present

Methionine sulfoxide reductase (MSR) is an important antioxidant to help mitigate oxidative stress that contributes to age-associated neurodegenerative diseases, such as Alzheimer’s Disease and Parkinson’s Disease. In MSR deficient Drosophila melanogaster (fruit flies), larvae show a developmental delay like that seen when wild-type larvae are reared on nutrient deficit culture medium. These investigators further showed that serotonin levels were depressed in these nutrient deficient larvae. The overarching aim of this study was to better understand the role of serotonin in MSR regulated physiology. Supplementing food with serotonin partially rescued the slower mouth hook movements (MHM) observed in the MSR-deficient flies. …

Efficient Machine Learning Algorithms For Identifying Risk Factors Of Prostate And Breast Cancers Among Males And Females, Samaneh Rikhtehgaran

Electronic Theses and Dissertations 2020 - Present

One of the most common types of cancer among women is breast cancer. It represents one of the diseases leading to a high number of mortalities among women. On the other hand, prostate cancer is the second most frequent malignancy in men worldwide. The early detection of prostate cancer is fundamental to reduce mortality and increase the survival rate. A comparison between six types of machine learning models as Logistic Regression, Decision Tree, Random Forest, Gradient Boosting, k Nearest Neighbors, and Naïve Bayes has been performed. This research aims to identify the most efficient machine learning algorithms for identifying the …

Evidence For The Independent Evolution Of Visual Perception During Seafinding By Hatchling Leatherback Sea Turtles (Dermochelys Coriacea), Samantha E. Trail

Electronic Theses and Dissertations 2020 - Present

Hatchling marine turtles exhibit a positive phototaxis by crawling toward the lowest and brightest horizon when they emerge from nests on the beach at night, which should lead them to the ocean (“seafinding”). Previous research with cheloniid (loggerhead and green turtle) hatchlings demonstrated that the perceptual spectral sensitivities are well below the light available on the beach regardless of lunar phase. The goal of this research was to determine the perceptual spectral sensitivities of leatherback hatchlings, the most distantly related of all extant sea turtle species. This study revealed that, like cheloniids, leatherbacks are most sensitive to shorter wavelengths (< 500 nm). However, leatherbacks were 10 – 100x less sensitive than cheloniids at all tested wavelengths. This difference in sensitivity corresponds with increased crawl duration and circling behavior under new moon conditions when light levels are lowest and the difference in radiance between the landward and seaward direction is small.

Flood Analysis In Nassau County, Florida, Michelle Hewett

Electronic Theses and Dissertations 2020 - Present

Flooding is a major threat to coastal and inland communities in the state of Florida. There are a variety of reasons for the increasing risk of flooding, such as hurricanes, torrential downpours, sea level rise, and storm surge/tides. This paper will focus on Nassau County, the most northeastern county in the state. While the area is affected by most of the aforementioned flood become more prominent over the years and will continue to impact the safety and well-being of coastal communities. In this context, planning for the future entails conducting multi-hazard analysis of risks posed by current and future storm …

G-Csf Gene Therapy For Brain Diseases And/Or Sickle Cell Anemia, Stefan Basilio

Electronic Theses and Dissertations 2020 - Present

Ischemic stroke is defined as a blockage or reduced flow of blood to select areas of brain tissue due to either plaque formation or buildup of blood clots in the small blood vessels. A characteristic of sickle cell anemic patients is the potential for them to experience a similar type of blockage due to the sticky nature of the sickled red blood cells as well as defective oxygen delivery to the brain. Because of this similarity, sickle cell anemia may represent a good animal research model for therapeutic intervention based on stroke models. In recent studies, Granulocyte-Colony Stimulating Factor (GCSF), …

Gcsf Gene Therapy For Parkinson’S Disease, Zachary Lee

Electronic Theses and Dissertations 2020 - Present

The kynurenine pathway plays a critical role in regulating immunological homeostasis in the brain. Evidence supporting the hypothesis that kynurenine pathway dysfunction may exacerbate progression of neurodegenerative diseases like Parkinson’s is growing. First, we investigate the effects of Interferon-γ, Lipopolysaccharide, and Interleukin-4 on several key kynurenine pathway metabolites using high performance liquid chromatography. We found that Interferon-γ had significant effects on the extracellular concentration of kynurenine metabolites in astrocytes, microglia, and macrophage. GCSF gene therapy is previously demonstrated to exert neuroprotective effects on models of Parkinson’s and Alzheimer’s disease. Seven days after receiving GCSF gene therapy, A53T Parkinson’s mice were …

Identification And Evaluation Of Critical Freight Corridors, Aline Anacleto Machado

Electronic Theses and Dissertations 2020 - Present

Efficient freight mobility plays a major role in the economy, and its performance is closely related to the quality of the transportation system. Requirements for funding transportation infrastructure projects often do not specify the analytical tools planners should use to request funding. Critical Urban and Rural Freight Corridors are sections of the National Highway Freight Network providing critical connectivity of goods and must have improved system performance. This research study offers a method for identifying these corridors considering temporal and spatial inputs. For this end, a multi-criteria spatial decision support system (MC-SDSS) was developed. This framework attributes a score to …

Identification Of Anti-Adhesion Small Molecules, Which Inhibit Sequestration Of Plasmodium-Falciparum Infected Erythrocytes, Using A Two-Step Approach, Pimnitah S. Visitdesotrakul

Electronic Theses and Dissertations 2020 - Present

A hallmark trait of P. falciparum malaria is sequestration, in which parasite infected erythrocytes (IEs) adhere to the vasculature, causing organ failure and death. Current antimalarials only kill the parasites, necessitating development of anti-adhesion drugs. Using our two-step approach, we can efficiently screen for anti-adhesion small molecules. Screenings of 75libraries using Bio-Plex 200 identified the most active TPI libraries, which were deconvoluted to single compounds. Screenings library TPI 1319 yielded 3 inhibiting non-optimized compounds, each of which inhibits binding between two receptors, CSA and ICAM1, and their binding PfEMP1 domains. Two compounds deconvoluted from TPI 2103 prevent binding between PfEMP1 …

Impact Of Sargassum Accumulations On Loggerhead Hatchling Recruitment To Nearshore Water On A Raked Urban Nesting Beach In Florida., Joshua P. Schiariti

Electronic Theses and Dissertations 2020 - Present

Hatchling loggerhead turtles emerge from subsurface nests on the beach at night, crawl down the beach and enter the sea. Recently, increases in a floating algae (Sargassum) has been reported in the mid-Atlantic and the Caribbean, resulting in large algal wrack on Florida beaches. The purpose of my study was to determine if these accumulations acted as a barrier, preventing hatchlings from completing their crawl to the sea. To address this issue I recorded seasonal changes in Sargassum density and directly observed when, and under what circumstances, hatchlings could cross the wrack. There was a significant overlap between when Sargassum …

Late Afternoon And Five Unspoken Stories, Mauricio J. Almonte

Electronic Theses and Dissertations 2020 - Present

The thesis consists of a novella and five short stories, all narrated from the perspective of a mute diasporic narrator who chronicles several returns to a nameless Caribbean village. Against a rich intertextual backdrop, these texts predominantly explore issues of mutism, the relationship between language and a sense of place, intricacies of translation, and the orality-literacy spectrum.

The Question Of A Federal Supreme Court In Germany 1806-1815, David Seleski

Electronic Theses and Dissertations 2020 - Present

The effectiveness and the sustainability of the Holy Roman Empire remained a subject of debate over the past two centuries. While nationalist historians derided the lack of centralized institutions, revisionist historians after the Second World War largely stressed the positive aspects of the Empire. The Reichskammergericht and the Reichshofrat were two of the institutions that experienced this positive reassessment. While most historians focused on the effectiveness of the Reich courts during the existence of the Empire, few have examined the perception of the courts immediately after the demise of the Empire in 1806. This thesis analyzes the perception of the …

The Relationship Between Principal Cultural Intelligence And Graduation Rates Of Black And Latinx Students: A Study Of Cultural Responsiveness In Public High School Principals, Melanie Ann Stefanovic

Electronic Theses and Dissertations 2020 - Present

Our nation’s culturally diverse public school students require transformative social justice school leadership that values, affirms, and includes all cultures. Studies focused on educational leadership for diverse student populations increasingly center around cultural responsiveness just as empirical studies on cultural intelligence (CQ) outside the field of education are also proliferating. This study was built upon a conceptual framework that highlights the overlaps between culturally responsive school leadership (CRSL) and the multi-dimensional framework of CQ. Based upon evidence of CQ as an antecedent to a number of positive outcomes in culturally diverse settings, the purpose was to uncover the extent to …

Yesterday We Were Girls, Katherine Prock

Electronic Theses and Dissertations 2020 - Present

Yesterday We Were Girls is a body of work which includes photographs selected from family albums and current images I create based in and around my childhood and adolescent memories. The photographs are accompanied by porcelain recreations of precious girlhood treasures, handwritten poetic prose, and an installation which also includes found furniture and a large open book form. Focused on my lived experience of the tension between intimacy and distance, acceptance and rejection, as well as the hidden and that which is laid bare, this body of work is an exploration of identity, female life cycles, family history, and mother …

Barriers To Scholarship Integration In Professional Athletic Training Programs And Resources Needed To Overcome Barriers: A Report From The Association For Athletic Training Education Research Network, Julie M. Cavallario, Cailee E. Welch, Stacy E. Walker, Lindsey E. Eberman

Rehabilitation Sciences Faculty Publications

Context: Athletic training program administrators have identified that it is important to incorporate a scholarship component into professional education curricula.

Objective: Explore the barriers to implementing student scholarship in professional programs and identify resources necessary to overcome the barriers.

Design: Consensual qualitative research.

Setting: Individual teleconference interview.

Patients or Other Participants: A total of 17 program directors of professional programs was interviewed.

Data Collection and Analysis: Programs reported an average of 3 ± 1 core faculty supporting 37 ± 21 students, with 3 ± 2 faculty involved in scholarship activities of their students. Data saturation guided the number of participants.Interviews …

Lumbopelvic Stability And Trunk Muscle Contractility Of Individuals With Chronic Ankle Instability, Ryan S. Mccann, Kelly Johnson, Ashley M.B. Suttmiller

Rehabilitation Sciences Faculty Publications

BACKGROUND: Chronic ankle instability (CAI) results in hip neuromuscular impairments that can perpetuate dysfunction through reduced lumbopelvic stability and subsequent malpositioning of the lower body during functional movement. Lumbopelvic stability might be further impaired through changes in trunk muscular contractility. However, lumbopelvic stability and trunk muscle morphology have not been compared between individuals with and without CAI.

PURPOSE: To compare lumbopelvic stability and trunk muscle contractility between individuals with and without chronic ankle instability (CAI) and determine if lumbopelvic stability and trunk muscle contractility are associated with self-reported function.

STUDY DESIGN: Case-control study.

METHODS: Ten individuals with CAI, 10 …

Employability In Academe For Athletic Trainers With The Doctor Of Athletic Training Degree, Bonnie L. Van Lunen, Stephanie H. Clines, Tyler Reems, Lindsey E. Eberman, Dorice A. Hankemeier, Cailee E. Welch

Rehabilitation Sciences Faculty Publications

The doctor of athletic training (DAT) degree has recently been introduced into academe. Limited literature exists regarding how individuals with this degree can become part of an athletic training faculty. To identify department chairs' perceptions of the DAT degree and determine whether they viewed the degree as viable when hiring new faculty within a postbaccalaureate professional athletic training program. Cross-sectional study. Online survey instrument. A total of 376 department chairs who had oversight of Commission on Accreditation of Athletic Training Education athletic training programs were invited to participate. Of these, 190 individuals (50.5%) accessed the survey, and 151 of the …

A Systematic Review Of Center Of Mass As A Measure Of Dynamic Postural Control Following Concussion, Sarah Patejak, Joshua Forrest, Emily Harting, Mable Sisk, Eric Schussler

Rehabilitation Sciences Faculty Publications

BACKGROUND: The incidence of sports-related concussion in the US is between 1.6-3.8 million annually. Identification of ongoing impairment post-concussion continues to be challenging, as research indicates many patients are cleared for return to activity while still suffering subclinical impairment of function. Purpose: To identify and review the current literature on the use of center of mass (COM) during gait as a potential indicator variable after concussive injury. Study Design: Systematic Review.

METHODS: A Pubmed search was undertaken utilizing search terms involving gait performance and concussion. Study inclusion criteria included: (1) COM used as a variable in data analysis, (2) study …

Celebrating Women Scholars In Athletic Training, Julie M. Cavallario, Cailee E. Welch Bacon, Lindsey E. Eberman, Stacy E. Walker

Rehabilitation Sciences Faculty Publications

No abstract provided.

Mitochondrial Regulation Of Diabetic Kidney Disease, Daniel L Galvan, Koki Mise, Farhad R Danesh

Faculty, Staff and Students Publications

The role and nature of mitochondrial dysfunction in diabetic kidney disease (DKD) has been extensively studied. Yet, the molecular drivers of mitochondrial remodeling in DKD are poorly understood. Diabetic kidney cells exhibit a cascade of mitochondrial dysfunction ranging from changes in mitochondrial morphology to significant alterations in mitochondrial biogenesis, biosynthetic, bioenergetics and production of reactive oxygen species (ROS). How these changes individually or in aggregate contribute to progression of DKD remain to be fully elucidated. Nevertheless, because of the remarkable progress in our basic understanding of the role of mitochondrial biology and its dysfunction in DKD, there is great excitement …

A Pharmacokinetic Analysis Of Hemodialysis For Metformin-Associated Lactic Acidosis, Stephen A Harding, Rana Biary, Robert S Hoffman, Mark K Su, Mary Ann Howland

Faculty, Staff and Students Publications

OBJECTIVE: Although hemodialysis is recommended for patients with severe metformin-associated lactic acidosis (MALA), the amount of metformin removed by hemodialysis is poorly documented. We analyzed endogenous clearance and hemodialysis clearance in a patient with MALA.

METHODS: A 62-year-old man with a history of type II diabetes mellitus presented after several days of vomiting and diarrhea and was found to have acute kidney injury (AKI) and severe acidemia. Initial serum metformin concentration was 315.34 μmol/L (40.73 μg/mL) (typical therapeutic concentrations 1-2 μg/mL). He underwent 6 h of hemodialysis. We collected hourly whole blood, serum, urine, and dialysate metformin concentrations. Blood, urine, …

Full Issue

Religious Educator: Perspectives on the Restored Gospel

No abstract provided.

Supporting Literacy And Comprehension In Religious Education, Stephen A. Nelson

Religious Educator: Perspectives on the Restored Gospel

Imagine the following scenario unfolding in a seminary classroom: The assigned scripture block that day is James chapter 1, and the instructor is anxious to facilitate a meaningful discussion focusing on verses 5 and 6. To help his students identify the principle “God generously gives wisdom to those who ask of him in faith,” he writes the following question on the board: “What did James advise his readers to do to find answers to their questions?”[1] After a compelling readiness activity, the teacher invites a young man to read James 1:5–6 aloud while the rest of the class follows along …

Thirsty Places, Priya Baskaran

Scholarly Articles in Law Reviews & Journals

The United States, among the wealthiest and most prosperous nations in the world, regularly fails to provide clean, potable water to many of its citizens. Recent water crises occur within communities categorized as Geographically Disadvantaged Spaces ("GDS'), which often encompass urban and rural areas. What is more, people of color and economically vulnerable populations are often located within GDS, disproportionately burdening these groups with the economic and public health consequences of failing water infrastructure. This article provides a novel, comparative analysis of communities lacking potable water in Flint, Michigan, and southern West Virginia. This analysis highlights entrenched structural problems present …

Legal Diplomacy In An Age Of Authoritarianism, Fernanda Giorgia Nicola Dr.

Scholarly Articles in Law Reviews & Journals

No abstract provided.

Difficulty Of Care: Aligning Tax And Health Care Policy For Family Caregiving, Christine Speidel

Scholarly Articles in Law Reviews & Journals

In the United States millions of people live with disabilities, many of whom require assistance with activities of daily life to remain in their homes and communities. However, financial support for this assistance is limited. Many caregivers forgo working outside the home in order to provide care to a family member. And while state and federal programs provide some compensation for caregiving, caregivers frequently face problems including poverty, lack of health insurance, lack of Social Security and Medicare credits, and lack of retirement savings. Our nation’s paltry support for caregiving threatens the practical ability of people with disabilities to choose …

Sham Subpoenas And Prosecutorial Ethics, Ira Robbins

Scholarly Articles in Law Reviews & Journals

Prosecutors are given broad freedom to conduct their investigations through-out the grand jury process; their power is not without legal and ethical limits, however. For example, courts have discretion to quash subpoenas that have been issued without a proper purpose. Unlike law enforcement officials who may use deceptive tactics throughout an investigation, prosecutors are subject to professional rules of responsibility. All lawyers are subject to some variation of Rule 4.2 of the Model Rules of Professional Responsibility—the No-Contact Rule—which prohibits a lawyer from communicating with a represented individual. Prosecutors, however, have escaped the Rule’s reach by communicating with represented individuals …

The Emerging Shape Of Global Justice: Retrogression Or Course Correction?, Diane Orentlicher

Scholarly Articles in Law Reviews & Journals

No abstract provided.

Symposium: Expanding Compassion Beyond The Covid-19 Pandemic, Jenny Roberts

Scholarly Articles in Law Reviews & Journals

Compassionate relief matters. It matters so that courts may account for tragically unforeseeable events, as when an illness or disability renders proper care impossible while a defendant remains incarcerated, or when family tragedy leaves an inmate the sole caretaker for an incapacitated partner or minor children. It matters too, as present circumstances make clear, when public-health calamities threaten inmates with literal death sentences. It matters even when no crisis looms, but simply when continued incarceration would be "greater than necessary" to achieve the ends of justice.

The Past, Present, And Future Of Investment Treaty Conflict Management And Dispute Systems Design, Susan Franck

Scholarly Articles in Law Reviews & Journals

ABSTRACT: International investment dispute resolution is in an era of unprecedented flux. At first blush, it might appear that major transforma- tions in international law are pulling in opposite directions. On the one hand, non-adjudicative dispute resolution and "alternative" dispute resolu- tion mechanisms like mediation are gaining traction, and with the creation of a Convention on the Enforcement of Mediated Settlement, it might ap- pear to reign supreme. On the other hand, traditional rule of law mecha- nisms, namely international courts, seem to be gaining momentum with the strong advocacy of the European Union for the creation of an …