Digital Commons Network^™

Solopreneur Digital Ecosystems: Genesis, Lineage And Preliminary Categorization, Gabriele Piccoli, Biagio Palese, Joaquin Rodriguez

Faculty Publications

This paper traces the genesis and lineage of solopreneur digital ecosystems. These ecosystems, fostered by a digital environment that is infrastructural, combinatorial and servitized, are enabling the rise to prominence of the solopreneur. We theorize solopreneur digital ecosystems as the latest incarnation of systems beyond firm control, with digital platforms and digital marketplaces as their principal enablers. In an effort to compare them from the perspective of the solopreneur, we categorize solopreneur digital ecosystems on three dimensions: algorithmic control, commoditization, and lock-in. Our work contributes a framework that solopreneurs can use to identify ecosystems in which they can optimally invest …

Are You There, Law? It's Me, Semen, Anita Bernstein

Faculty Scholarship

No abstract provided.

The Aoc In The Age Of Covid - Pandemic Preparedness Planning In The Federal Courts, Zoe Niesel

Faculty Articles

The 2020 COVID-19 pandemic created a crisis for American society—and the federal courts were not exempt. Court facilities came to a grinding halt, cases were postponed, and judiciary employees adopted work-from-home practices. Having court operations impacted by a pandemic was not a new phenomenon, but the size, scope, and technological lift of the COVID-19 pandemic was certainly unique.

Against this background, this Article examines the history and future of pandemic preparedness planning in the federal court system and seeks to capture some of the lessons learned from initial federal court transitions to pandemic operations in 2020. The Article begins by …

The End Of The Golden Age Of American Legal Education: My Year As Interim Dean, Vincent R. Johnson

Faculty Articles

This article is part of the story of my year as interim dean. The year began without a sign of trouble anywhere on the horizon and ended with an empty campus, cancellation of traditional law school events, face masks and social distancing requirements, uncertainty about whether new law graduates would be able to take the bar exam, and furloughs and layoffs of law school personnel. As my year drew to a close, dozens of American law school deans were meeting online every Friday to share information about how to cope with the challenges of the Covid-19 Pandemic and the uncertainties …

R2u3d: Recurrent Residual 3d U-Net For Lung Segmentation, Dhaval D. Kadia, Md Zahangir Alom, Ranga Burada, Tam Nguyen, Vijayan K. Asari

Computer Science Faculty Publications

3D Lung segmentation is essential since it processes the volumetric information of the lungs, removes the unnecessary areas of the scan, and segments the actual area of the lungs in a 3D volume. Recently, the deep learning model, such as U-Net outperforms other network architectures for biomedical image segmentation. In this paper, we propose a novel model, namely, Recurrent Residual 3D U-Net (R(2)U3D), for the 3D lung segmentation task. In particular, the proposed model integrates 3D convolution into the Recurrent Residual Neural Network based on U-Net. It helps learn spatial dependencies in 3D and increases the propagation of 3D volumetric …

At A Covid Crossroads: Public Health, Patient Privacy, And Health Information Confidentiality, Stacey A. Tovino

Saint Louis University Law Journal

This essay summarizes and assesses the various bulletins, guidance documents, and notices of enforcement discretion released by the federal Department of Health and Human Services regarding the application of the HIPAA Privacy Rule to the COVID-19 pandemic. Among other topics and actions, these authorities address the application of the HIPAA Privacy Rule to the use and disclosure of protected health information for public health activities, waive the application of certain HIPAA Privacy Rule requirements during the COVID-19 pandemic, and announce enforcement discretion regarding certain covered entities’ non-compliance with particular provisions within the HIPAA Privacy Rule. These authorities overwhelmingly, and appropriately, …

Covid-19 And Public Accommodations Under The Americans With Disabilities Act: Getting Americans Safely Back To Restaurants, Theaters, Gyms, And “Normal”, Frank Griffin

Saint Louis University Law Journal

COVID-19 permanently changed the way places of public accommodation like restaurants, theaters, medical facilities, arenas, gyms, and many other proprietors of mainstream American activities must operate in order to accommodate people with newly-defined, COVID-19-related disabilities under Title III of the Americans with Disabilities Act (ADA). The required modifications will affect all patrons and employees of these establishments. Under the ADA, places of public accommodation are barred from discriminating against people with disabilities in the full and equal enjoyment of goods, services, and facilities. Infectious diseases like tuberculosis and HIV have been categorized as disabilities under the ADA, and COVID-19 is …

Mobilizing World Public Opinion Against Use Of Plastic Products, Kishor Dere

California Western Law Review

No abstract provided.

Vascular Access (2nd Ed.), Registered Nurses' Association Of Ontario

General Submissions: Community and Population-based Materials

The purpose of this best practice guideline (BPG) is to provide nurses (nurse practitioners, registered nurses, registered practical nurses and nursing students) and other members of the interprofessional team with evidence-based recommendations and resources related to the insertion, assessment and maintenance of vascular access devices (VADs) in the infant (0-;1 year), pediatric (1-;18 years) and adult populations (18 years and older).

For more information including supplementary documents and available translations visit: https://rnao.ca/bpg/guidelines/Vascular_Access

The Risks Of Stone Diagnosis And Stone Removal Procedure After Different Bariatric Surgeries, Steven M. Monda, Joel M. Vetter, Margaret A. Olsen, Matthew R. Keller, J. Christopher Eagon, Michael S. Chevinsky, Vasian Markollari, Ramakrishna Venkatesh, Alana C. Desai

Open Access Publications

No abstract provided.

Unexpected Role Of Sterol Synthesis In Rna Stability And Translation In Leishmania, Zemfira N Karamysheva, Samrat Moitra, Andrea Perez, Sumit Mukherjee, Elena B Tikhonova, Andrey L Karamyshev, Kai Zhang

Open Access Publications

No abstract provided.

Engaging Caregivers And Providers Of Children With Sickle Cell Anemia In Shared Decision Making For Hydroxyurea: Protocol For A Multicenter Randomized Controlled Trial, Anna M Hood, Allison A King, Cecelia Calhoun, Et Al

Open Access Publications

BACKGROUND: Sickle cell anemia (SCA) is a genetic blood disorder that puts children at a risk of serious medical complications, early morbidity and mortality, and high health care utilization. Until recently, hydroxyurea was the only disease-modifying treatment for this life-threatening disease and has remained the only option for children younger than 5 years. Evidence-based guidelines recommend using a shared decision-making (SDM) approach for offering hydroxyurea to children with SCA (HbSS or HbS/β0 thalassemia) aged as early as 9 months. However, the uptake remains suboptimal, likely because caregivers lack information about hydroxyurea and have concerns about its safety and potential long-term …

Development And Validation Of A Multivariable Prediction Model For Missed Hiv Health Care Provider Visits In A Large Us Clinical Cohort, April C. Pettit, Aihua Bian, Cassandra O. Schember, Peter F. Rebeiro, Jeanne C. Keruly, Kenneth H. Mayer, W. Christopher Mathews, Richard D. Moore, Heidi M. Crane, Elvin Geng, Sonia Napravnik, Bryan E. Shepherd, Michael J. Mugavero

Open Access Publications

Background: Identifying individuals at high risk of missing HIV care provider visits could support proactive intervention. Previous prediction models for missed visits have not incorporated data beyond the individual level.

Methods: We developed prediction models for missed visits among people with HIV (PWH) with ≥1 follow-up visit in the Center for AIDS Research Network of Integrated Clinical Systems from 2010 to 2016. Individual-level (medical record data and patient-reported outcomes), community-level (American Community Survey), HIV care site-level (standardized clinic leadership survey), and structural-level (HIV criminalization laws, Medicaid expansion, and state AIDS Drug Assistance Program budget) predictors were included. Models were developed …

Evaluation Of A Clinical Decision Support Strategy To Increase Seasonal Influenza Vaccination Among Hospitalized Children Before Inpatient Discharge, Evan W. Orenstein, Omar Elsayed-Ali, Swaminathan Kandaswamy, Erin Masterson, Reena Blanco, Pareen Shah, Patricia Lantis, Amy Kolwaite, Thomas E. Dawson, Edwin Ray, Christy Bryant, Srikant Iyer, Andi L. Shane, Stephanie Jernigan

Open Access Publications

Importance: Hospitalized children are at increased risk of influenza-related complications, yet influenza vaccine coverage remains low among this group. Evidence-based strategies about vaccination of vulnerable children during all health care visits are especially important during the COVID-19 pandemic.

Objective: To design and evaluate a clinical decision support (CDS) strategy to increase the proportion of eligible hospitalized children who receive a seasonal influenza vaccine prior to inpatient discharge.

Design, Setting, and Participants: This quality improvement study was conducted among children eligible for the seasonal influenza vaccine who were hospitalized in a tertiary pediatric health system providing care to more than half …

Cd16+Cd163+ Monocytes Traffic To Sites Of Inflammation During Necrotizing Enterocolitis In Premature Infants, Oluwabunmi O. Olaloye, Misty Good, Et Al

Open Access Publications

Necrotizing enterocolitis (NEC) is a severe gastrointestinal complication of prematurity. Using suspension and imaging mass cytometry coupled with single-cell RNA sequencing, we demonstrate severe inflammation in patients with NEC. NEC mucosa could be subtyped by an influx of three distinct neutrophil phenotypes (immature, newly emigrated, and aged). Furthermore, CD16+CD163+ monocytes/Mϕ, correlated with newly emigrated neutrophils, were specifically enriched in NEC mucosa, found adjacent to the blood vessels, and increased in circulation of infants with surgical NEC, suggesting trafficking from the periphery to areas of inflammation. NEC-specific monocytes/Mϕ transcribed inflammatory genes, including TREM1, IL1A, IL1B, and calprotectin, and neutrophil recruitment genes …

Extracorporeal Support Prognostication-Time To Move The Goal Posts?, Neel Shah, Ahmed S Said

Open Access Publications

Advances in extracorporeal membrane oxygenation (ECMO) technology are associated with expanded indications, increased utilization and improved outcome. There is growing interest in developing ECMO prognostication scores to aid in bedside decision making. To date, the majority of available scores have been limited to mostly registry-based data and with mortality as the main outcome of interest. There continues to be a gap in clinically applicable decision support tools to aid in the timing of ECMO cannulation to improve patients' long-term outcomes. We present a brief review of the commonly available adult and pediatric ECMO prognostication tools, their limitations, and future directions.

An Open Label, Block Randomized, Community Study Of The Safety And Efficacy Of Co-Administered Ivermectin, Diethylcarbamazine Plus Albendazole Vs. Diethylcarbamazine Plus Albendazole For Lymphatic Filariasis In India, Purushothaman Jambulingam, Vijesh Sreedhar Kuttiatt, Kaliannagounder Krishnamoorthy, Swaminathan Subramanian, Adinarayanan Srividya, Hari Kishan K. Raju, Manju Rahi, Roopali K. Somani, Mallanna K. Suryaprakash, Gangeshwar P. Dwivedi, Gary J Weil

Open Access Publications

No abstract provided.

Pandemic, Plague, Pestilence And The Tropics: Critical Inquiries From Arts, Humanities And Social Sciences, Anita Lundberg, Kalala J. Ngalamulume, Jean Segata, Arbaayah Ali Termizi, Chrystopher J. Spicer

History Faculty Research and Scholarship

The Tropics have long been associated with exotic diseases and epidemics. This historical imaginary arose with Aristotle’s notion of the tropics as the ‘torrid zone’, a geographical region virtually uninhabitable to temperate peoples due to the hostility of its climate, and persisted in colonial imaginaries of the tropics as pestilential latitudes requiring slave labour. The tropical sites of colonialism gave rise to urgent studies of tropical diseases which lead to (racialised) changes in urban planning. The Tropics as a region of pandemic, plague and pestilence has been challenged during the COVID-19 pandemic. The novel coronavirus did not (simply) originate in …

Just Plain Dumb?: How Digital Contact Tracing Apps Could’Ve Worked Better (And Why They Never Got The Chance), Brian E. Ray

Law Faculty Articles and Essays

This essay describes how the privacy debate that emerged over digital contact tracing and Google’s and Apple’s decisions to strictly limit apps permitted to use their platforms resulted in undercutting their potential usefulness as a tool to combat the pandemic while still failing to engender trust in these tools as intended.

Towards An Ontology-Based Approach To The "New Normality" After Covid-19:The Spanish Case During Pandemic First Wave, Evelio Gonzalez

Turkish Journal of Electrical Engineering and Computer Sciences

The impact of the pandemic caused by COVID-19 has been immense in all fields of human activity. In most of the affected countries, the authorities have decreed a series of legal measures to try to stop the growth of the disease and the number of people affected by it. These legal measures involved, in most cases, restrictions on the free movement of people and on work and trade activities, new hygiene procedures, and social distancing. In the particular case of Spain, the rapid evolution of the pandemic led to the declaration of a so-called state of alarm and a period …

No Payment, No Procreative Liberty: The Case Against Restrictions And Prohibitions On Payment For Gametes, Chloe Nelson

Student Works

No abstract provided.

A 'Public' Journey Through Covid-19: Donald Trump, Twitter, And The Secrecy Of U.S. Presidents’ Health, Mark Fenster

UF Law Faculty Publications

Donald Trump ignored numerous governance norms in his one term as U.S. President, especially those that prescribe disclosure of official and personal financial information. His brief period of illness from COVID-19, which he broadcast to the world via his Twitter account, revealed the complexity of Trump’s relationship to the concept and norms of transparency that presume information’s necessity for a functional and accountable state. At the same time that Trump offered little in the way of coherent and authoritative information about his health, he also provided an enormous amount of seemingly “inside” and direct accounts of the progress of his …

Validity Of A Four-Item Household Water Insecurity Experiences Scale For Assessing Water Issues Related To Health And Well-Being, Sera L. Young, Joshua D. Miller, Edward A. Frongillo Jr., Godfred O. Boateng, Zeina Jamaluddine, Torsten B. Neilands

Faculty Publications

We sought to determine whether a shortened version of the 12-item Household Water Insecurity Experiences (HWISE) Scale, which measures water insecurity equivalently in low- and middle-income countries (LMICs), is valid for broad use. Using data from 9,261 households in 25 LMICs, subsets of candidate items were evaluated on their predictive accuracy, criterion validity, and sensitivity-specificity. A subset with items assessing "worry," "changing plans," "limited drinking water," and "inability to wash hands" because of problems with water (range: 0-12) were highly correlated with full HWISE Scale scores (correlation coefficient: 0.949-0.980) and introduced minimal additional error (root mean square error: 2.13-2.68). Criterion …

Role Of Gravin/Akap12 Variants In Regulating Endothelial Cell Behavior, Ashrifa Ali

Theses and Dissertations

A functional endothelium must maintain an equilibrium among processes such as endothelial cell (EC) migration, barrier function and angiogenesis. The endothelium is constantly exposed to external factors that that result in a complex network of signaling wired to several possible cellular outcomes. A-kinase anchoring proteins (AKAPs) have a critical role in regulating cell signaling by providing spatial and temporal control of signaling proteins to increase downstream target specificity. Several studies have linked gravin (also called SSeCKS or AKAP12), an AKAP, to migration, barrier function, and angiogenesis. However, the functional significance of each gravin variant in ECs has not been investigated …

Monocyte Abundance And White Blood Cell Expression Of Prolactin And Nf-Kb Pathway Genes In Beef Steers Are Altered By Grazing Toxic Endophyte-Infected Tall Fescue And Lipopolysaccharide Challenge, Cecilia Winfrey

Theses and Dissertations--Animal and Food Sciences

Experiment 1 tested the hypothesis that ad libitum consumption of a 1:1 blend (MIX) of sodium selenite (ISe) and SELPLEX vs solely ISe as selenium (Se) supplements (27 ppm) in a vitamin-mineral mix (V-M) by steers subjected to summer-long grazing of toxic endophyte-infected tall fescue (TE) would ameliorate the negative effects of TE by positively affecting the expression pattern of prolactin (PRL) and NF-kB pathway genes by circulating leukocytes (WBC). Experiment 2 tested the hypothesis that the MIX form of supplemental Se also would ameliorate the negative effects of in vitro blood lipopolysaccharide challenge (LPS) on WBC gene expression. The …

Association Between Learning Methods And Analgesic Opioid Abuse, Nicole Marie Blanchard

Walden Dissertations and Doctoral Studies

Opioids are an extremely addictive class of medication used to treat pain; overprescribing practices and chronic misuse has led to an epidemic that continues to grow. The opioid epidemic not only has the potential to cause injury or even death but also has a large impact on the U.S. economy. Research regarding determinants of abuse are needed to improve safeguards for opioid abuse prevention. The purpose of this quantitative study was to determine if learning capabilities and/or learning medium preference are correlated with analgesic opioid abuse. The social-ecological model was used to evaluate the social levels of influence for abuse …

New Graduate Nurses’ Transfusion Training Views: Reflection On Experiences With Adverse Reactions, Hind Jaber-Daou

Walden Dissertations and Doctoral Studies

Abstract:New graduate nursing students transitioning to becoming professionals undergo education and training to gain knowledge and competence about transfusions. Nonetheless, new graduate nurses experience stress during a blood transfusion adverse reaction, which can be associated with lack of knowledge and inadequate training. The purpose of this qualitative study was to gather data from new graduate nurses who described their lived experiences with patients exhibiting symptoms of adverse reactions, how they reflected on their emotional effects, and the influences of the training on their knowledge and confidence. The research was grounded in social cognitive theory that centers on the concept of …

Public Health Policing And The Case Against Vaccine Mandates, Dr. Tryon Woods

St. Thomas Law Review

There can be no simple reading of a text, be it literary, philosophical or scientific, nor of the social text in the most general sense. Rather, the question must turn upon itself, no less than its putative object, as a matter of interpretation and, more important, as a matter of the forces at work in the interpretative activity under way. There is always the ascription of voice to what is otherwise silent, the attribution of a face or the placement of a mask. Le germe n’est rien, c’est le terrain qui est tout. The microbe is nothing, the soil is …

Self-Adjuvanted Virus-Like Particle For Safe And Highly Immunogenic Vaccination, Yiwen Zhao

Open Access Dissertations

Vaccination is one of the most outstanding inventions in medical history and has made significant contributions to prevent various types of infectious diseases. Once highly fatal disease, smallpox, was eradicated in 1980 after decades of vaccination effort. Mounting evidence also supports vaccination as the most effective way to control the recent outbreak of COVID-19.

Different types of vaccines have been developed from the early inactivated and live-attenuated vaccines to recent subunit vaccines, and to recent emerging nucleic acid-based vaccines that vary in vaccine immunogenicity and safety. Subunit vaccines are attractive vaccine types due to its good safety profiles, flexible design, …

Covid-19, Courts, And The 'Realities Of Prison Administration.' Part Ii: The Realities Of Litigation, Chad Flanders

All Faculty Scholarship

Lawsuits challenging prisons and jails for not doing enough to stop the spread of COVID-19 among inmates have faced mixed results in the courts: wins at the district court level are almost always followed by losses (in the form of stays of any orders to improve conditions) at the appeals court level or at the Supreme Court. This short article tries to explain why this is happening, and makes three comparisons between how district courts and appeals courts have analyzed these lawsuits. First, district courts and appeals courts tend to emphasize different facts in their decisions. District courts focus more …