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Foreword: Interactions Between Religion And Medicine In Eastern Europe During The Sars-Cov-2 Pandemic: Social Context, Iurii Kuchyn, Nataliia Ishchuk

Occasional Papers on Religion in Eastern Europe

A special issue of OPREE, dedicated to the interaction of religion and medicine, is being released on the anniversary of the struggle of humankind against the SARS-CoV-2 pandemic. Unfortunately, hopes of overcoming the infection quickly proved futile. The outbreak of this infectious disease has caused chaos in the private and social lives of billions of people. It changed the usual rhythm and forced people to obey new rules. For many people, it caused job and income loss and changes in personal priorities. For most people, the question of reappraisal of values arose when the need for self-realization gave way to …

Everyone Matters: Eliminating Dehumanizing Practices In Physical Education, Brian Culp

Faculty Articles

Recently, discussions regarding how to create a positive school climate where all can be successful has come to the forefront. Healthy schools support student learning, well-being, time, space to be active, and opportunities for social and emotional growth. However, a host of numerous trends suggest that the school climate is becoming increasingly hostile towards students who are from immigrant, LBGTQ, and ethnic minority groups. What is often seen as disrespectful behavior toward these students is in fact actions that can be more accurately defined as dehumanization. This article overviews the practice of dehumanization, the implications for learning, and introduces proactive …

Increased Mood Disorder Symptoms, Perceived Stress, And Alcohol Use Among College Students During The Covid-19 Pandemic, Nora E. Charles, Stephanie J. Strong, Lauren C. Burns, Margaret R. Bullerjahn, Katherine M. Serafine

Faculty Publications

The COVID-19 pandemic caused significant disruption during the spring of 2020. Many college students were told to leave campus at spring break and to complete the semester remotely. This study evaluates effects of this disruption on student well-being. Measures of psychological symptoms, perceived stress, and alcohol use during the pandemic were completed by 148 students in spring 2020 and 352 students in fall 2020 at a university in the southeastern U.S. Results from both cohorts were compared to 240 students who completed the same measures in the fall 2019 semester. Participants in spring 2020 reported more mood disorder symptoms, perceived …

Hiv-1 Latency And Viral Reservoirs: Existing Reversal Approaches And Potential Technologies, Targets, And Pathways Involved In Hiv Latency Studies, Sushant Khanal, Madison Schank, Mohamed El Gazzar, Jonathan P. Moorman, Zhi Q. Yao

ETSU Faculty Works

Eradication of latent human immunodeficiency virus (HIV) infection is a global health challenge. Reactivation of HIV latency and killing of virus-infected cells, the so-called “kick and kill” or “shock and kill” approaches, are a popular strategy for HIV cure. While antiretroviral therapy (ART) halts HIV replication by targeting multiple steps in the HIV life cycle, including viral entry, integration, replication, and production, it cannot get rid of the occult provirus incorporated into the host-cell genome. These latent proviruses are replication-competent and can rebound in cases of ART interruption or cessation. In general, a very small population of cells harbor provirus, …

Trimming Type I Interferon-Mediated Innate Immune Response In Antiviral And Antitumor Defense, Ling Wang, Shunbin Ning

ETSU Faculty Works

The tripartite motif (TRIM) family comprises at least 80 members in humans, with most having ubiquitin or SUMO E3 ligase activity conferred by their N-terminal RING domain. TRIMs regulate a wide range of processes in ubiquitination-or sumoylation-dependent manners in most cases, and fewer as adaptors. Their roles in the regulation of viral infections, autophagy, cell cycle progression, DNA damage and other stress responses, and carcinogenesis are being increasingly appreciated, and their E3 ligase activities are attractive targets for developing specific immunother-apeutic strategies for immune diseases and cancers. Given their importance in antiviral immune response, viruses have evolved sophisticated immune escape …

Primary Care In A Pandemic: A Qualitative Study On The Impact Of Covid-19 On Workplace Wellness, Oriana Pando, Amy Cunningham, Erin Kelley, Randa Sifri, Kelsey Smith

Phase 1

Introduction:

On March 16, 2020, the city of Philadelphia announced a state of emergency due to the COVID-19 global pandemic. The Primary Care Department of Thomas Jefferson Hospital had to alter operations to protect patients, providers and staff. These changes included an increase in telehealth, personal protective equipment (PPE), spacing in-person visits, and working from home. This study was designed to qualitatively assess how these changes have impacted providers and staff in Jefferson’s primary care settings.

Methods:

We conducted 31 qualitative semi-structured interviews with employees of Jefferson Primary Care practices. Though, our population was heavily skewed toward clinical staff (N=9), …

Results Of The 2020 Immunization Status Survey Of 24-Month Old Children In Tennessee, Tennessee. Department Of Health.

Immunization Rates

No abstract provided.

Strategically Rational Risk Taking By Age In Covid-19, And The Heterogeneous Agent Behavioral Sir Model, Siamak Javadi, Elena Quercioli, Lones Smith

School of Economics and Finance Faculty Publications

Given the dramatic age variation in COVID death rates, we create a heterogeneous agent version of the Behavioral SIR contagion model of Engle et al. (2020). The Bayes Nash equilibrium of our infection avoidance game yields a simple new log-linear relationship between the case fatality rate (CFR) and COVID incidence: Everyone knows that everyone optimizes vigilance both for the prevalence and their CFR. We explain 2020 CDC incidence data for the USA north-east in terms of the CFR to age-specific COVID death data for Massachusetts. Our model is statistically significant: A 10% higher CFR reduces incidence by about 1%.

Implications Of Covid-19 On Progress In The Un Conventions On Biodiversity And Climate Change, Andrea Monica D. Ortiz, Alaya M. De Leon, Justine Nicole V. Torres, Cecilia Therese T. Guiao, Antonio Gabriel M. La Viña

Environmental Science Faculty Publications

2020 was to be a landmark year for setting targets to stop biodiversity loss and prevent dangerous climate change. However, COVID-19 has caused delays to the 15th Conference of the Parties (COP) of the UN Convention on Biological Diversity and the 26th COP of the UN Framework Convention on Climate Change. Negotiations on the Global Biodiversity Framework and the second submission of Nationally Determined Contributions under the Paris Agreement were due to take place at these COPs. There is uncertainty as to how the COVID-19 disruption will affect the negotiations, whether parties will pursue more ambitious actions or take a …

Maternal And Newborn Health Risks Of Climate Change: A Call For Awareness And Global Action, Nathalie Roos, Sari Kovats, Shakoor Hajat, Veronique Filippi, Matthew Chersich, Stanley Luchters, Fiona Scorgie, Britt Nakstad, Olof Stephansson, Chamnha Consortium

Population Health, East Africa

Climate change represents one of the largest global health threats of the 21st century with immediate and long‐term consequences for the most vulnerable populations, especially in the poorest countries with the least capacity to adapt to climate change. Pregnant women and newborns are increasingly being recognized as vulnerable populations in the context of climate change. The effects can be direct or indirect through heat stress, extreme weather events and air pollution, potentially impacting both the immediate and long‐term health of pregnant women and newborns through a broad range of mechanisms. In 2008, the World Health Organization passed a resolution during …

Synergistic Efficacies Of Thymoquinone And Standard Antibiotics Against Multi-Drug Resistant Isolates, Ayed A. Dera, Irfan Ahmad, Prasanna Rajagopalan, Mesfer Al Shahrani, Ahmed Saif, Mohammad Y. Alshahrani, Yasser Alraey, Ahmad M. Alamri, Sultan Alasmari, Mohammed Makkawi, Ali G. Alkhathami, Gaffar Zaman, Abdulrahim Hakami, Razan Alhefzi, Mohammad A. Alfhili

Saudi Medical Journal

Objectives: To explore the antibacterial activity of thymoquinone (TQ), a quinone extracted from Nigella sativa . Methods: This study was conducted from May 2019 to March 2020 at the Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia. The antimicrobial activity, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) of TQ were determined using an agar well diffusion method and broth microdilution assays, and the synergistic effect was evaluated using antibiotics in parallel. The disruptive effect of TQ on bacterial cell membranes was determined using scanning electron microscopy. The antivirulence properties of …

Distribution And Antibiotic Resistance Profiles Of Salmonella Enterica In Rural Areas Of North Carolina After Hurricane Florence In 2018, Yuqing Mao, Mohamed Zeineldin, Moiz Usmani, Sital Uprety, Joanna Shisler, Antarpreet Jutla, Avinash Unnikrishnan, Thanh H. Nguyen

Civil and Environmental Engineering Faculty Publications and Presentations

The frequency and magnitude of extreme events are increasing globally (Arnell & Gosling, 2016). Inundation, as a result of massive flooding, has the potential to change environmental conditions abruptly, and as a result, add pressure to the metabolism and proliferation of microorganisms (Furtak et al., 2020). The resulting overland flows and additional burden from domestic sewer and septic tank systems during an extreme flood event can introduce pathogens into ecologically unstable water bodies. For example, Yu et al. (2018) reported elevated levels of Escherichia coli and antibiotic resistance genes (ARGs) in river water samples 6 months after flooding in Houston, …

Comparing The Quality Of An In-Person Versus Virtual Diabetes Education Course Due To Covid 19 Pandemic, Allie Hamilton, Rickie Brawer, Phd

Phase 1

Introduction: Group diabetes education courses are proven to improve patients’ diabetes knowledge and metabolic control. Due to the COVID19 pandemic, Stephen Klein Wellness Center (SKWC) shifted their diabetes education course to an online format over Zoom. This study aimed to investigate difference in patient experience and course effectiveness between the in-person and online courses.

Methods: The population for this study includes 89 patients at SKWC that completed either the in-person or online diabetes education course. Participant satisfaction was measured with phone interviews and a survey. Course effectiveness was measured using surveys to assess the change in patients’ weight, amount of …

Student Well-Being In The Time Of Covid: Survey Of Online Students’ Coping, Ellen Catherine Coble

Theses and Dissertations

The emergence of the COVID-19 pandemic has presented the global population with a considerable stressor resulting in significant loss of life, impaired health, disrupted social practices, and economic atrophy. While many have been impacted and are currently being studied, a population less frequently considered in the literature is that of online college students. Previous research has indicated the influence of several factors on college students’ well-being when coping with stress under typical circumstances such as coping strategies (e.g., problem-focused, emotion-focused, and avoidant/dysfunctional), experiential avoidance, and social support. Studies performed in the wake of large-scale crises highlight proximity to the crisis …

Characterization And Localization Of Antigens For Serodiagnosis Of Human Paragonimiasis, Kurt C Curtis, Kerstin Fischer, Young-Jun Choi, Makedonka Mitreva, Gary J Weil, Peter U Fischer

2020-Current year OA Pubs

Paragonimiasis is a foodborne trematode infection that affects 23 million people, mainly in Asia. Lung fluke infections lead frequently to chronic cough with fever and hemoptysis, and are often confused with lung cancer or tuberculosis. Paragonimiasis can be efficiently treated with praziquantel, but diagnosis is often delayed, and patients are frequently treated for other conditions. To improve diagnosis, we selected five Paragonimus kellicotti proteins based on transcriptional abundance, recognition by patient sera, and conservation among trematodes and expressed them as His-fusion proteins in Escherichia coli. Sequences for these proteins have 76-99% identity with amino acid sequences for orthologs in the …

Std Prevention: An Educational Intervention For Exotic Dancers, Maria Delurdes Dehoyos

Electronic Theses and Dissertations

The Centers for Disease Control and prevention reported nearly 2.3 million STD cases diagnosed in 2017, and the number is continuing to rise. San Antonio, Texas, is ranked third in the state of Texas with the highest STD rates and leading in the state with congenital syphilis. There is an increased risk for contracting STDs working in the sex industry. There are little to no studies pertaining to any educational interventions offered to exotic dancers to increase personal knowledge on STDs. This research has focused on an educational intervention offered by a nurse practitioner to exotic dancers in two adults-only …

High Prevalence Of Multidrug-Resistant Clostridioides Difficile Following Extensive Use Of Antimicrobials In Hospitalized Patients In Kenya, Winnie C. Mutai, Marianne W. Mureithi, Omu Anzala, Gunturu Revathi, Brian Kullin, Magdaline Burugu, Cecilia Kyany’A, Erick Odoyo, Peter Otieno, Lillian Musila

Pathology, East Africa

Introduction: Clostridioides difficile is a neglected pathogen in many African countries as it is generally not regarded as one of the major contributors toward the diarrheal disease burden in the continent. However, several studies have suggested that C. difficile infection (CDI) may be underreported in many African settings. The aim of this study was to determine the prevalence of CDI in hospitalized patients, evaluate antimicrobial exposure, and detect toxin and antimicrobial resistance profiles of the isolated C. difficile strains.

Methods: In this cross-sectional study, 333 hospitalized patients with hospital-onset diarrhoea were selected. The stool samples were collected and cultured on …

Religious Epidemics On The Territory Of Ukraine: Historical Parallels And Essential Characteristics, Olena Predko, Denis Predko

Occasional Papers on Religion in Eastern Europe

The article deals with two religious epidemics that unfolded in Ukraine in a span of one hundred years. The study analyzes the factors influencing the emergence and development of religious epidemics. On this basis, their peculiar algorithm has been singled out, the components of which are, on the one hand, the worldview and crisis of values caused by the rapid turns of history, and—on the other—-choosiness by God, charisma of the leader of a particular organization, which is “fed” by an eschatological idea, syncretic teachings, which are cultivated as an alternative religious model to established traditions. The definition of a …

How Christians Of The First Centuries Experienced Epidemics, Maryna Lukashenko, Lidiya Biletska

Occasional Papers on Religion in Eastern Europe

The article examines the ethical responses of the Christian communities of the first centuries to the challenges of the Antonine Plague and the Plague of Cyprian. During these times, the institutionalization and development of the Christian church took place, and thus the strategies of its social service and behavior in the conditions of acute social crises and trials were developed. Already during the first epidemics, the Christian communities showed a radically different attitude to the sick and sufferers than was accepted in the society of that time. This attitude was based on Christian love and charity, self-sacrifice and service to …

“All Enemies, Foreign And Domestic”: The Presence Of Anti-Latinx Political Rhetoric And Latinxs As Third World Threats In Secondary U.S. Citizenship Curriculum, Christopher Busey, Álvaro José Corral, Erika L. Davis

Political Science Faculty Publications

Background/Context

Anti-Latinx political discourses have long positioned Latin America and, by extension, U.S. Latinxs as economic, sociocultural, and political threats to the general welfare of the United States. In formal school curricula, this threat narrative has become one of the many political curricular discourses for codifying citizenship as White, and noncitizens as Other (read Black, Indigenous, Latinx, Asian American).

Purpose/Objective/Research Question/Focus of Study

The purpose of this study was to illustrate how collapsible Latin American tropes and current anti-Latinx sentiments are reproduced in social studies curricula across the United States. Drawing from and expanding upon Leo Chavez's notion of the …

In Vitro Evaluation Of Novel Titania-Containing Borate Bioactive Glass Scaffolds, Romina Shafaghi, Omar Rodriguez, Anthony W. Wren, Loraine Chiu, Emil H. Schemitsch, Paul Zalzal, Stephen D. Waldman, Marcello Papini, Mark R. Towler

Chemical and Biochemical Engineering Faculty Research & Creative Works

Titanium-containing borate bioactive glass scaffolds (0, 5, 15, and 20 mol %, identified as BRT0, BRT1, BRT3, and BRT4) with a microstructure similar to that of human trabecular bone were prepared and evaluated in vitro for potential bone loss applications in revision total knee arthroplasty (rTKA). Methyl thiazolyl tetrazolium (MTT) cell viability assays of scaffold ion release extracts revealed that BRT0 scaffolds (0 mol % titanium) inhibited cell proliferation and activity at day 14. At day 30, all scaffold extracts decreased cell proliferation and activity significantly. However, live/dead cell assay results demonstrated that degradation products from all the scaffolds had …

Rrh Library Newsletter, February 2021, Libraries At Rochester Regional Health

Rochester Regional Health authored publications and proceedings

Newsletter sections include: Vaccine Hesitancy; Library Services during COVID-19

The Fungus Leptosphaerulina Persists In Anopheles Gambiae And Induces Melanization, Godfrey Nattoh, Joel L. Bargul, Gabriel Magoma, Lilian Mbaisi, Hellen Butungi, Enock Mararo, Evan Teal, Jeremy Keith Herren

All Peer-Reviewed Publications

Anopheles mosquitoes are colonized by diverse microorganisms that may impact on host biology and vectorial capacity. Eukaryotic symbionts such as fungi have been isolated from Anopheles, but whether they are stably associated with mosquitoes and transmitted transstadially across mosquito life stages or to subsequent generations remains largely unexplored. Here, we show that a Leptosphaerulina sp. fungus isolated from the midgut of An. gambiae can be stably associated with An. gambiae host and that it imposes low fitness cost when re-introduced through co-feeding. This fungus is transstadially transmitted across An. gambiae developmental stages and to their progeny. It is present in …

Disparities In Sars-Cov-2 Positivity Rates: Associations With Race And Ethnicity, Harvey W Kaufman, Justin K Niles, David B. Nash

College of Population Health Faculty Papers

Numerous reports indicate that African Americans and Latinos are being affected disproportionately by coronavirus disease 2019 (COVID-19). Positivity rates have not been analyzed on scale because only 4 states report race/ethnicity as part of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing. Previous studies also have had little ability to control for many known risk factors to better identify the effects of COVID-19 on racial and ethnic communities. Using test results from a large national reference laboratory database that included patients from all 50 states and the District of Columbia, this study compared positivity rates for SARS-CoV-2 nucleic acid amplification …

The Quest For Conquering Covid-19: Updates From The Laboratory, David B. Nash

College of Population Health Faculty Papers

No abstract provided.

Immune Checkpoint Inhibitor Therapy In Hiv-Associated Merkel Cell Carcinoma: A Case Series Of 3 Patients., Song Y Park, Candice Church, Nora A Alexander, Michi M Shinohara, Kelly G Paulson, Karl D Lewis, Nancy S Lee, Paul Nghiem

Articles, Abstracts, and Reports

No abstract provided.

Microbiome: Role And Functionality In Human Nutrition Cycle, Fahad Alhusain

Saudi Medical Journal

ABSTRACT Microbes are present almost everywhere on this Earth. Humans harbor microbes in various organs, including skin, gut, mouth, and nose. Among these, the gut region has the highest population of microbes. Gut microbiota is directly linked with homeostasis, and a minor change in their numbers predisposes humans to ailments. Notably, the role of the microbial population in the digestive tract directly contributes to body weight. Sometimes, lifestyle changes or antibiotics intake to manage certain infections are associated with disturbance in the gut microflora. Several scientific studies allude to the obesity linkage with disturbed intestinal microflora. This review mainly focuses …

A Scientometric Analysis Of Global Literature On Hydroxychloroquine Based On Scopus, Gururaj S. Hadagali, Iranna M. Shettar, Lokesh Shashtri, B Ramesh Babu

Library Philosophy and Practice (e-journal)

This paper deals with the scientometric analysis of the global literature on Hydroxychloroquine as indexed in SCOPUS database from its first publication in 1946 to 2020. The objective of the study was to perform a scientometric analysis of Hydroxychloroquine publications. The study analyzed 25,163 publications which were contributed by 88,834 individual authors affiliated to 159 countries. The results showed momentum in the research publications during the 1980s and accelerated immediately from the beginning of the 21st century. It was observed a fluctuating trend for the Annual Growth Rate and CAGR recorded to 0.129635. The Relative Growth Rate recorded between 0.04 …

Global Research Performance On Covid 19 In Dimensions Database, Jeyapragash Balasubramani, Muthuraj Anbalagan

Library Philosophy and Practice (e-journal)

Purpose: This paper examines the global research performance on COVID 19 in Dimensions Database. Dimensions contains more than 100 million publications, ranging from articles published in scholarly journals, books and book chapters, to preprints and conference proceedings.

Methodology: The data were extracted from Dimensions Website (https://app.dimensions.ai/discover/publication). The word “Covid 19” has been used to retrieve the data as on 2^nd December 2020. A total of 200852 records and 810426 citations received for the year 1871-2020. The study also analyzed top twenty researchers, source wise publications, funding wise publications, types of publications and top twenty highly cited research …

Hyperglycemia And Dyslipidemia: Reduced Hla-Dr Expression In Monocyte Subpopulations From Diabetes Patients, Blanca I. Restrepo, Marcel Twahirwa, Chinnaswamy Jagannath

School of Medicine Publications

Immune dysfunction contributes to the higher risk of communicable and non-communicable diseases among diabetics. HLA-DR expression is a robust marker of immune competence in mononuclear cells, including antigen presentation to CD4 lymphocytes. Given the high prevalence of obesity among diabetics, we evaluated the independent association between hyperglycemia and dyslipidemias with respect to HLA-DR expression in blood monocytes from type 2 diabetes patients. The monocytes from individuals with (n=16) or without diabetes (n=25) were phenotyped by flow cytometry to assess the differential expression of HLA-DR on their three subpopulations (classical, intermediate and non-classical monocytes). Diabetes was independently associated with lower HLA-DR …