Digital Commons Network^™

Arsenic: It’S Not Just For Rats. The Benefits Of Arsenic Trioxide For The Treatment Of Acute Promyelocytic Leukemia, Lauren Sheldon

Nursing Doctoral

Purpose: The purpose of this review is to compare the effectiveness of induction therapy with arsenic trioxide (ATO) paired with retinoic acid (ATRA) and standard chemotherapy for the treatment of newly diagnosed acute promyelocytic leukemia (APL).

Background and Significance: The use of chemotherapy for APL treatment has demonstrated successful results, but is associated with toxicities. Research has shown that the use of ATO/ATRA not only achieves complete molecular remission, but also increased survival rates and reduced disease relapse.

Methods: Databases used include CINAHL, PubMed, and ProQuest Nursing and Allied Health. Keywords searched were induction treatment, acute promyelocytic leukemia, arsenic trioxide, …

Simulated Contact Tracing Of Covid-19 Propagation At Kutztown University For Fall 2020, Dale E. Parson

Computer Science and Information Technology Faculty

From mid-May through August 2020 the author designed, built, revised, and analyzed resulting data from two simulation programs for virtual contact tracing of COVID-19 infection propagation at Kutztown University in the fall 2020 semester. The first was command-line driven and non-graphical, with results distributed to faculty and administrators on May 28. The second was a three-dimensional interactive graphical simulation, distributed to faculty, administrators, and the public as a narrated video via YouTube on July 16. The algorithm is an adaptation of spreading activation as used in theoretical psychology and artificial intelligence research since the 1970s. It propagates discrete, probable infections …

Uab-Developed Viral Immunotherapy For Pediatric Brain Tumors Shows Promise, Alicia Rohan

Browse All News

No abstract provided.

Healthcare Disparities Among Incarcerated Pregnant Women, Molly Carpenter, Halim Oluwatunmise, Whitney Shipley, Ojiugo Udensi

Epsilon Sigma at-Large Research Conference

No abstract provided.

The 'English Bath': English Sweating Sickness And The 1529 Continental Outbreak, Anika Esther Martin

Phi Alpha Theta Pacific Northwest Regional Conference

Abstract: Sudor Anglicus, or "English Sweating Sickness," was a peculiar disease which afflicted England during the Tudor period. First appearing in the late summer of 1485, Sweating Sickness quickly proved itself to be a terrifying killer. Those who contracted the Sweat were struck ill suddenly, often died within the first twenty-four hours, and suffered from a host of symptoms, the most visible of which being a raging fever and oppressive sweat. Between 1485 and 1551, five major outbreaks of the disease wracked the country, attracting the worried attention of those beyond England. In 1529, those anxieties were realized when a …

The Development And Validation Of Covid-19 Prevention Behaviour Scale On Female Hungarian Population, Kinga Kalcza-Janosi, Susana Jancso-Farcas, Kinga Szabo, Ibolya Kotta, Eszter E. Marschalkó

Journal of International Women's Studies

In the emergency situation of an ongoing global pandemic, disease prevention behaviour is essential. The majority of studies assess preventive behaviour through relevant unidimensional questions, but this approach is not necessarily the best way to conceptualize prevention, as health maintenance guidelines cover several different areas of possible individual precautionary and preventive practices. The aim of the study is the development and validation of a multidimensional COVID-19 prevention behaviour scale for the Hungarian speaking population (Covid-19-PBS). The items address major aspects related to preventive behaviour towards COVID-19 inspired by preliminary pandemic studies and the WHO prevention recommendations. 612 eligible female individuals …

The Moderation Effect Of Generation On The Relationship Between Psychological Flexibility And Covid-19 Preventive Behaviour Among Females, Ibolya Kotta, Kinga Szabo, Eszter E. Marschalkó, Susana Jancso-Farcas, Kinga Kalcza-Janosi

Journal of International Women's Studies

Disease prevention behaviour is essential during the ongoing COVID-19 pandemic. How people respond to information and regulations to control this infectious disease can be influenced by their age and generational identity. An individual with an optimal level of psychological flexibility can adapt to challenging situations more efficiently. Hence, the purpose of the present study was to investigate the moderating effect of generation on the relationship between psychological flexibility and COVID-19 preventive behaviour among different generational cohorts of women (baby boomers, X, Y, and Z). This relationship was rarely addressed in the literature, which is what inspired this study. Data were …

Covid-19: A Call For Legal And Institutional Reform, Steve (Y.S.) Lee

Law Review Blog Posts

COVID-19 has caused an unprecedented health crisis in the United States and the world. The article calls for legal and institutional reform to better manage present and future pandemics.

2021-April-09-Etsu Health Covid-19 Vaccine Clinics April 10 And 13, University Marketing And Communication, East Tennessee State University

ETSU News

Following federal guidance released from the FDA and the CDC this morning, ETSU Health is canceling its Johnson & Johnson Janssen COVID-19 vaccine clinic scheduled for Tuesday, April 13, 2021.  All patients who had appointments today will be notified via text messaging and are encouraged to schedule vaccines at alternative vaccine sites that are offering either the Moderna or Pfizer COVID-19 vaccines. To learn where you can receive a Pfizer or Moderna vaccine, go to www.vaccinefinder.org. To schedule an appointment to receive a Pfizer vaccine from Ballad, go to https://www.balladhealth.org/medical-services/infectious-disease#schedule. Ballad currently has sites in Elizabethton, Kingsport, and …

Characterizing Micronutrient Status And Risk Factors Among Late Adolescent And Young Women In Rural Pakistan: A Cross-Sectional Assessment Of The Mapps Trial, Jo-Anna B. Baxter, Yaqub Wasan, Amjad Hussain, Sajid Bashir Soofi, Imran Ahmed, Zulfiqar Ahmed Bhutta

Woman and Child Health

Nutritional deficiencies are a leading underlying risk factor contributing to the global burden of disease. In Pakistan, late adolescence is considered a nutritionally vulnerable period, as micronutrient requirements are increased to support maturation, and dietary staples are nutrient poor. However, there has been limited evaluation of micronutrient status beyond anemia and its determinants. Using cross-sectional data from late adolescent and young women (15-23 years) at enrolment in the Matiari emPowerment and Preconception Supplementation (MaPPS) Trial, we aimed to describe the prevalence of key micronutrient deficiencies of public health concern, and generate hierarchical models to examine associations with proxies for social …

Interview With Jon Molina (1522), Jorge Arroliga, Jon Molina

Voces of a Pandemic

No abstract provided.

Pfmfr3: A Multidrug-Resistant Modulator In Plasmodium Falciparum, Frances Rocamora, Purva Gupta, Eva S Istvan, Madeline R Luth, Emma F Carpenter, Krittikorn Kümpornsin, Erika Sasaki, Jaeson Calla, Nimisha Mittal, Krypton Carolino, Edward Owen, Manuel Llinás, Sabine Ottilie, Daniel E Goldberg, Marcus C S Lee, Elizabeth A Winzeler

2020-Current year OA Pubs

In malaria, chemical genetics is a powerful method for assigning function to uncharacterized genes. MMV085203 and GNF-Pf-3600 are two structurally related napthoquinone phenotypic screening hits that kill both blood- and sexual-stage

Predicting Cognitive Rehabilitation Needs In Patients With Central Nervous System Infections Using Montreal Cognitive Assessment, Matilde Ørum, Merete Storgaard, Paul Denton, Trine Hyrup Mogensen, Christina Kjærgaard Højbjerg, Mathilde Pedersen, Jesper Damsgaard Gunst

Biology Faculty Publications

Cognitive impairments are reported in some patients with central nervous system (CNS) infections after discharge. Our objectives were to evaluate the prevalence of CNS patients in need of rehabilitation after discharge and to assess whether the Montreal Cognitive Assessment (MoCA) could be used as a screening tool to identify these patients. CNS patients admitted during a 2-year study period were included. The need for rehabilitation was assessed by physicians with the aid of an occupational therapy assessment, after which a MoCA was performed. The prevalence of needing rehabilitation was 58% among CNS patients. An abnormal MoCA score < 26 was the only variable strongly associated with higher odds of needing rehabilitation. In 42% of the CNS patients in need of rehabilitation, the MoCA score was ≥ 26, and most of these patients were aged 16 to 43 years (young adults). There is a need for rehabilitation among CNS patients after discharge. As a screening tool, MoCA was able to identify patients in need of rehabilitation. In young adults, MoCA scores were often normal despite a need for rehabilitation. Thus, MoCA cannot stand alone as a screening tool for identifying young adults in need of rehabilitation following CNS infection.

Why Deteriorating Relations, Xenophobia, And Safety Concerns Will Deter Chinese International Student Mobility To The United States, Ryan M. Allen, Ying Ye

Education Faculty Articles and Research

Collaborations between American and Chinese universities have been critical to global knowledge production. Chinese students accounted for over a third of all international students in the United States prior to COVID-19, but the pandemic paused most global mobility in 2020. We argue that this international mobility to the United States will not fully recover if larger stressors are left unaddressed. First, relations between the United States and China have deteriorated in recent years, especially under the Trump administration, with growing suspicion against Chinese researchers and scholars. Second, viral acts of violence and anti-Asian incidents have painted the United States as …

State V. Hewlett Appellant's Brief Dckt. 48352

Not Reported

No abstract provided.

Quarantine Ethics: From Past To Covid-19, Chrystal Barnes

OHSU-PSU School of Public Health Annual Conference

Quarantines have been a preventative measure for reducing communicable disease spread for centuries. The method of implementation can vary widely and to some extent requires some level of judgement from enforcing powers, often state police power. As such, historically, some quarantines have been unfairly enforced based on discriminatory practices. COVID-19 has brought about the most widespread and extended quarantine in U.S. history, which makes evaluating the ethics all the more critical. In addition, it is well established that COVID-19 impacts have disproportionately caused harm to populations, such as those who are of a low socioeconomic status and people of color. …

Ontology Of Library And Information Science Theses Of The Central Universities In India, Syamili C Dr., Rekha Rv Dr.

Library Philosophy and Practice (e-journal)

The study attempted to design the ontology of Library and Information Science theses of central universities of India to visualize the doctoral research output in Library Information Science. The study also attempts to develop the ontology using ‘Methontology’, which is an ontology engineering methodology to explore the method. This Ontology contains 247 concepts, 244 Individuals, 125 Object property assertions, 85 Data property assertions. The developed ontology was evaluated and made sure that it meets the information need of its users and it has been found that Ontology could answer the majority of the questions after evaluation. The evaluation results are …

The Crosstalk Between Insulin Resistance, Systemic Inflammation, Redox Imbalance And The Thyroid In Subjects With Obesity, Nicoleta Răcătăianu, Nicoleta Valentina Leach, Sorana D. Bolboacă, Maria Loredana Soran, Mirela Flonta, Ana Valea, Andrada-Luciana Lazăr, Cristina Ghervan

Journal of Mind and Medical Sciences

We aimed at assessing the interaction between visceral adipose tissue (VAT), insulin resistance (IR), circulating levels of monocyte chemoattractant protein-1 (MCP-1) and malondialdehyde (MDA) and the thyroid parameters in obese subjects. Methods. Obese subjects without thyroid pathologies or diseases associated with systemic inflammation and OS were recruited. Insulinemia, visceral fat thickness, metabolic and thyroid parameters were assayed. Circulating levels of MCP-1 and MDA were used to quantify inflammation and OS. Results. A number of 160 obese subjects were included. The MCP-1 level increased with the degree of obesity and HOMA-IR. MCP 1 was positively associated with antithyroperoxidase antibody (TPOab) levels …

D-Dimer Levels And Acute Pulmonary Embolism Development In Covid-19 Patients, Vural Ahmet, Kahraman Ahmet Nedim

Journal of Mind and Medical Sciences

Objective. To identify those who develop pulmonary embolism with Ddimer levels by evaluating pulmonary CT angiographies of patients who are followed up with suspicion of coronavirus disease 2019 (COVID-19). Methods. Patients who were followed up in a community hospital with suspicion of COVID-19 and underwent Pulmonary CT angiography examination were evaluated. Clinical and demographic parameters and DDimer values for patients with and without pulmonary embolism were evaluated in the pulmonary CT angiogram. Results. During the COVID-19 pandemic, Thorax CT examination was performed in our center for suspicion or follow-up of COVID-19 infection in 3396 patients. Pulmonary CT angiography was applied …

Modern Approaches For Antiandrogen-Resistant Prostate Cancer Therapy, Felix Voinea, Laura Mazilu, Ioan Sergiu Micu, Adrian Paul Suceveanu, Madalina Iliescu, Andrada Dumitru, Vlad Denis Constantin, Ioana Paunica, Andra Iulia Suceveanu

Journal of Mind and Medical Sciences

Prostate cancer represents the leading malignant tumor in men over 50 years of age with 400,000 new cases being diagnosed yearly in Europe. Even if the incidence rate is higher than the mortality rate, still there is an increasing trend when speaking of its mortality. The increasing incidence of the metabolic syndrome, the unhealthy lifestyle, the high lipid and Calcium intake, the high spread of infections with Human Papilloma Virus, Human Herpes Virus, the excess of androgen consumption and the longer life expectancy, are few of the main causes of prostate cancer increasing incidence. The new systemic therapies such as …

Aspects Of Climate Change, Anthony Defusco

English Department: Research for Change - Wicked Problems in Our World

Climate change continues to become a global issue, and with that, more people being affected by the harmful factors that come with it. Climate change not only effects the environment, but also has aspects of cultural and health issues. Different cultures view this problem differently than other as it affects different aspects of that culture. Health risk is on the rise as air pollution is more prominent and diseases spread. The climate is being warmed, causing extreme weather and drought. These different perspectives on global warming allow for new and unknowing people to be exposed to this issue and allow …

April 8, 2021: Covid-19 Campus Update, Kettering University

Communication Updates

Topics in this Update:

COVID-19 Vaccines

COVID-19 Testing Exemptions

Safe Campus 2021

Vol.48 N.38 April 8th 2021, Voice Media Ventures

Black Voice News

No abstract provided.

April 8, 2021, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Influence Of Previous Covid-19 And Mastitis Infections On The Secretion Of Brain-Derived Neurotrophic Factor And Nerve Growth Factor In Human Milk, Veronique Demers-Mathieu, Dustin J. Hines, Rochelle M. Hines, Sirima Lavangnananda, Shawn Fels, Elena Medo

Psychology Faculty Research

Background: Brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) play a critical role in neurodevelopment, where breast milk is a significant dietary source. The impact of previous COVID-19 infection and mastitis on the concentration of BDNF and NGF in human milk was investigated. Methods: Concentrations of BDNF and NGF were measured via ELISA in human milk samples collected from 12 mothers with a confirmed COVID-19 PCR, 13 mothers with viral symptoms suggestive of COVID-19, and 22 unexposed mothers (pre-pandemic Ctl-2018). These neurotrophins were also determined in 12 mothers with previous mastitis and 18 mothers without mastitis. Results: The NGF …

The Importance Of Right To Science During Pandemics, Natallia Sianko, Albina Balidemaj, Mark Small

Articles

Few articles of the Universal Declaration of Human Rights (UDHR) have received less attention than the right to science. All signatory members agreed that the right of everyone to “share in scientific advancement and its benefits” [Article 27(1)] is to be promoted and protected in every place around the globe (United Nations, 1948). The right to science is further secured in the International Covenant on Economic, Social and Cultural Rights (ICESCR). This not only reaffirms it as a basic human right, but also, upon coming into force in 1976, established the responsibility of governments to respect the right of everyone …

The New Hampshire, Vol. 110 [111], No. 54 (Apr. 8, 2021), The New Hampshire

The New Hampshire Print Edition

An independent student produced newspaper from the University of New Hampshire. This volume was printed as 110, but it is the 111th volume in the series. This was corrected in pencil.

Covid-19 And Preparing Planetary Health For Future Ecological Crises: Hopes From Glycomics For Vaccine Innovation, Xueqing Wang, Zhaohua Zhong, Wei Wang

Research outputs 2014 to 2021

A key lesson emerging from COVID-19 is that pandemic proofing planetary health against future ecological crises calls for systems science and preventive medicine innovations. With greater proximity of the human and animal natural habitats in the 21st century, it is also noteworthy that zoonotic infections such as COVID-19 that jump from animals to humans are increasingly plausible in the coming decades. In this context, glycomics technologies and the third alphabet of life, the sugar code, offer veritable prospects to move omics systems science from discovery to diverse applications of relevance to global public health and preventive medicine. In this expert …

'Health And Safety First': Town Hall Addresses Return To Campus, Matt Windsor

Browse All News

No abstract provided.

Effects Of News And Threat Perceptions On Americans’ Covid-19 Precautionary Behaviors, Riva Tukachinsky Forster, Megan A. Vendemia

Communication Faculty Articles and Research

Our study examines the relationship between news exposure at the onset of the COVID-19 pandemic, personal threat beliefs, beliefs about others’ threat perceptions, and participation in precautionary actions. A survey of 377 U.S . adults revealed a significant main effect of news exposure on various precautionary behaviors (e.g., facial mask wear, physical distancing). Personal threat beliefs and beliefs about others’ threat perceptions serve as unique mechanisms mediating the effect of news on specific CDC-recommended and less socially desirable actions. These findings can guide news sources covering health crises in a socially responsible manner.