Digital Commons Network^™

Taylor Alumna Pursues Master's In Global Health, Biosecurity And Disaster Preparedness, Taylor University

2021 Website News Stories

No abstract provided.

A Microbiota-Directed Food Intervention For Undernourished Children, Robert Y Chen, Matthew C Hibberd, Arjun S Raman, Daniel Webber, Cyrus Zhou, Vinaik Sundaresan, Kazi Ahsan, Martin F Meier, Michael J Barratt, Jeffrey I Gordon, Et Al

Open Access Publications

BACKGROUND: More than 30 million children worldwide have moderate acute malnutrition. Current treatments have limited effectiveness, and much remains unknown about the pathogenesis of this condition. Children with moderate acute malnutrition have perturbed development of their gut microbiota.

METHODS: In this study, we provided a microbiota-directed complementary food prototype (MDCF-2) or a ready-to-use supplementary food (RUSF) to 123 slum-dwelling Bangladeshi children with moderate acute malnutrition between the ages of 12 months and 18 months. The supplementation was given twice daily for 3 months, followed by 1 month of monitoring. We obtained weight-for-length, weight-for-age, and length-for-age z scores and mid-upper-arm circumference …

Rn Perception Of Resources, Communication, And Leadership During Covid-19 And The Impact On Rn Satisfaction And Turnover In A Multi-Hospital System, Gina Bullington

DNP Projects

Abstract

While RN retention has been a perennial challenge, COVID-19 has exacerbated the problem. The project’s purpose was to study RNs’ perception of communication, resources, and leadership during COVID-19, and the impact on RN turnover in a multi-hospital system. 3280 RNs’ engagement survey responses and turnover percentages from pre-COVID-19 (November 2019) were compared to engagement survey responses and turnover percentages 12 months later (November 2020). 90% (n = 2963) were female and 43% (n = 1396) were between the ages of 25 and 39 years. The majority of RN respondents were employed 1-9 years (59%, n = 1934). …

Changes In Body Mass Index Among Antiretroviral Therapy Naïve People Living With Hiv In Southeastern Nigeria, John O. Olawepo, Jennifer R. Pharr, Chad L. Cross, Babayemi O. Olakunde, Chinedu Aniekwe, Mercy Niyang, Raisa Kabir, Ayodotun Olutola

Environmental & Global Health Faculty Research

The proportion of people living with HIV (PLHIV) who are overweight or obese is rising, leading to a double epidemic of HIV and obesity. The purpose of this retrospective longitudinal study was to examine changes in body mass index (BMI) among PLHIV who were new to antiretroviral therapy (ART) in two states in Southeastern Nigeria. The BMI at baseline and 12 months were compared and the difference in proportions in each BMI category was tested. The association between the BMI at 12 months and the demographic and/or clinical variables was examined using multiway analysis of covariance. The study included 2,146 …

Summary, Campus Advisory Board Meeting, April 22, 2021, University Of South Florida St. Petersburg. Campus Board

Campus Board Minutes

Summary of a meeting of the Campus Advisory Board for the University of South Florida St. Petersburg held on April 22, 2021.

Respiratory Pathogens In Patients With Acute Exacerbation Of Non-Cystic Fibrosis Bronchiectasis From A Developing Country, Shayan Shahid, Kausar Jabeen, Nousheen Iqbal, Joveria Farooqi, Muhammad Irfan

Medical College Documents

Bronchiectasis unrelated to cystic fibrosis (non-CF bronchiectasis) has become a major respiratory disease in developing nations. The dilated mucus filled airways promote bacterial overgrowth followed by chronic infection, bronchial inflammation, lung injury and re-infection Accurate pathogen identification and antimicrobial susceptibility allowing appropriate treatment, in turn, may break this vicious cycle. To study the spectrum and antimicrobial spectrum of pathogen yielded from respiratory specimens in adult patients with acute exacerbation of non-cystic fibrosis (CF) bronchiectasis. This cross-sectional study was performed at the pulmonology clinics of the Aga Khan University, Karachi, Pakistan from 2016-2019. Respiratory specimens were collected from adult patients with …

How Do Canadian Public Health Agencies Respond To The Covid-19 Emergency Using Social Media: A Protocol For A Case Study Using Content And Sentiment Analysis, Anita Kothari, Lyndsay Foisey, Lorie Donelle Phd, Rn, Fcan, Michael Bauer

Publications

INTRODUCTION: Keeping Canadians safe requires a robust public health (PH) system. This is especially true when there is a PH emergency, like the COVID-19 pandemic. Social media, like Twitter and Facebook, is an important information channel because most people use the internet for their health information. The PH sector can use social media during emergency events for (1) PH messaging, (2) monitoring misinformation, and (3) responding to questions and concerns raised by the public. In this study, we ask: what is the Canadian PH risk communication response to the COVID-19 pandemic in the context of social media? METHODS AND ANALYSIS: …

Carbapenems: A Literature Review Regarding Resistance, Risk Factors, And Mortality In Pneumonia, Tania R. Amalia, Eli Halimah, Riyadi Adrizain, Miski A. Khairinisa

Pharmacology and Clinical Pharmacy Research

Carbapenem is one of antibiotic to treat respiratory infections such as pneumonia that frequently used in tertiary care facilities and started to create resistances. This study aims to review the resistance of carbapenems, assess the risk factors for resistance that leads to mortality, and the more effective antibiotic treatment options to overcome the resistance. Assessment of the use of carbapenems in pneumonia through previous studies were carried out by searching the articles in search engine databases in 2011 to 2021. Articles reporting carbapenems resistance, risk factors, and mortality were selected based on inclusion and exclusion criteria. Of 14 articles included …

Pneumatosis Intestinalis And Intestinal Perforation In A Case Of Multisystem Inflammatory Syndrome In Children, Lela Heza, Aliza Olive, Jenna Miller

Student Publications

This case demonstrates pneumatosis intestinalis and small bowel perforation in a paediatric patient with multisystem inflammatory syndrome in children (MIS-C). Our patient presented with fever, abdominal pain and shortness of breath. She progressed to haemodynamic failure and small bowel perforation approximately 1 week after admission. Patients with suspected or confirmed MIS-C should be monitored closely for abdominal catastrophe, especially when critically ill in the intensive care unit.

Sars Pandemic Exposure Impaired Early Childhood Development In China, Yunfei Fan, Huiyu Wang, Quong Wu, Xiang Zhou, Yubo Zhou, Bin Wang, Yiqun Han, Tao Xue, Tong Zhu

Department of Educational Studies Faculty Publications

Social and mental stressors associated with the pandemic of a novel infectious disease, e.g., COVID-19 or SARS may promote long-term effects on child development. However, reports aimed at identifying the relationship between pandemics and child health are limited. A retrospective study was conducted to associate the SARS pandemic in 2003 with development milestones or physical examinations among longitudinal measurements of 14,647 children. Experiencing SARS during childhood was associated with delayed milestones, with hazard ratios of 3.17 (95% confidence intervals CI: 2.71, 3.70), 3.98 (3.50, 4.53), 4.96 (4.48, 5.49), or 5.57 (5.00, 6.20) for walking independently, saying a complete sentence, counting …

Wastewater Surveillance For Sars-Cov-2 On College Campuses: Initial Efforts, Lessons Learned, And Research Needs, Sasha Harris-Lovett, Kara L. Nelson, Paloma Beamer, Heather N. Bischel, Aaron Bivins, Andrea Bruder, Caitlyn Butler, Todd D. Camenisch, Susan K. De Long, Smruthi Karthikeyan, David A. Larsen, Katherine Meiediercks, Paula J. Mouser, Sheree Pagsuyoin, Sarah M. Prasek, Tyler S. Radniecki, Jeffrey L. Ram, D. Keith Roper, Hannah Safford, Samendra P. Sherchan, William Shuster, Thibault Stalder, Robert T. Wheeler, Katrina Smith Korfmacher

Pharmacy Faculty/Staff Publications

Wastewater surveillance for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging approach to help identify the risk of a coronavirus disease (COVID-19) outbreak. This tool can contribute to public health surveillance at both community (wastewater treatment system) and institutional (e.g., colleges, prisons, and nursing homes) scales. This paper explores the successes, challenges, and lessons learned from initial wastewater surveillance efforts at colleges and university systems to inform future research, development and implementation. We present the experiences of 25 college and university systems in the United States that monitored campus wastewater for SARS-CoV-2 during the fall 2020 academic …

Mastomys Natalensis Has A Cellular Immune Response Profile Distinct From Laboratory Mice, Tsing Lee Tang-Huau, Kyle Rosenke, Kimberly Meade-White, Aaron Carmody, Brian J. Smith, Catharine M. Bosio, Michael A. Jarvis, Heinz Feldmann

School of Biomedical Sciences

The multimammate mouse (Mastomys natalensis; M. natalensis) has been identified as a major reservoir for multiple human pathogens including Lassa virus (LASV), Leishmania spp., Yersinia spp., and Borrelia spp. Although M. natalensis are related to well-characterized mouse and rat species commonly used in laboratory models, there is an absence of established assays and reagents to study the host immune responses of M. natalensis. As a result, there are major limitations to our understanding of immunopathology and mechanisms of immunological pathogen control in this increasingly important rodent species. In the current study, a large panel of commercially available rodent reagents were …

2021-04-21_Michiganoverview_Covidtestingtimes, Michigan Department Of Health & Human Services

Michigan COVID-19 Testing Turnaround Data

The COVID Testing Turnaround Time page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173-545615--,00.html.

This report was created by the Michigan Department of Health & Human Services, providing data for the past 14 days on the average time it takes for a diagnostic COVID-19 laboratory test to be reported to the state health department. Testing turnaround time data will be updated weekly on Friday mornings.

MDHHS receives results from commercial labs, hospitals, and public health labs. However, public health laboratories perform limited diagnostic testing and disease surveillance for infectious diseases. Total turnaround time is calculated from the difference of …

2021-04-21_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

We Are...Marshall, April 21, 2021, Office Of Marshall University Communications

We Are ... Marshall: the Newsletter for Marshall University 1999-2023

No abstract provided.

From Bunks And Bars To Sidewalks And Skies: Support For Reentry From Incarceration, Ashley Ann Steen

Theses and Graduate Projects

Currently, there are over 2.3 million inmates in the prison system throughout the United States (Bureau of Justice Statistics, 2018). Over 10,000 ex-prisoners are released from America's state and federal prisons every week and studies show that approximately two-thirds will likely be rearrested within three years of release (Bureau of Justice Statistics, 2018). This scholarly project will explore the literature on why inmates face such a high rate of recidivism. It will further explore the current programming that is provided to inmates prior to release back to the community and offer a questionnaire to utilize in all reentry programs to …

Optimized Polyepitope Neoantigen Dna Vaccines Elicit Neoantigen-Specific Immune Responses In Preclinical Models And In Clinical Translation, Lijin Li, Xiuli Zhang, Xiaoli Wang, Samuel W Kim, John M Herndon, Michelle K Becker-Hapak, Beatriz M Carreno, Nancy B Myers, Mark A Sturmoski, Michael D Mclellan, Christopher A Miller, Tanner M Johanns, Benjamin R Tan, Gavin P Dunn, Timothy P Fleming, Ted H Hansen, S Peter Goedegebuure, William E Gillanders

2020-Current year OA Pubs

BACKGROUND: Preclinical studies and early clinical trials have shown that targeting cancer neoantigens is a promising approach towards the development of personalized cancer immunotherapies. DNA vaccines can be rapidly and efficiently manufactured and can integrate multiple neoantigens simultaneously. We therefore sought to optimize the design of polyepitope DNA vaccines and test optimized polyepitope neoantigen DNA vaccines in preclinical models and in clinical translation.

METHODS: We developed and optimized a DNA vaccine platform to target multiple neoantigens. The polyepitope DNA vaccine platform was first optimized using model antigens in vitro and in vivo. We then identified neoantigens in preclinical breast cancer …

Treatment Of Acute Bronchitis In Active Duty Military Members Benchmark Project, Nicole Williams

MSN Capstone Projects

Antibiotic resistant infections are a growing problem in the United States and the world. The main cause of this is antibiotic prescriptions, which can not only cause antibiotic resistance but adverse events. Decreasing the amount of antibiotics prescribed for inappropriate conditions can help to decrease the rates of antibiotic resistant infections and the problems these infections can cause. One illness that is treated frequently with antibiotics, against recommendations, is acute bronchitis. Acute bronchitis is a self-limiting viral infection, characterized by cough. By decreasing the number of providers who are prescribing antibiotics for acute bronchitis, the clinic can help to prevent …

A Guide To Helminth Parasites Reported From Shorebirds (Charadriidae) From The Americas, Albert G. Canaris, Sofia Capasso, Gay J. Canaris

MANTER: Journal of Parasite Biodiversity

The shorebird family Charadriidae in the Americas consists of 21 native and 7 vagrant species. Members of the family occupy a diversity of open habitats, ranging from Arctic tundra during nesting, coastal sands, and mudflats to inland prairies, savannas, and wetlands. Some native plovers migrate from nesting grounds in North America to wintering grounds in South America (Hayman et al., 1986; Paulson, 2005; Winkler et al., 2020). Our search of the literature revealed the following: 17 of 28 host species infected with helminth parasites, 153 helminth species, and 199 infections involving 13 geographic areas. The purpose of this guide is …

Insects Provide Unique Systems To Investigate How Early-Life Experience Alters The Brain And Behavior, Rebecca R. Westwick, Clare C. Rittschof

Entomology Faculty Publications

Early-life experiences have strong and long-lasting consequences for behavior in a surprising diversity of animals. Determining which environmental inputs cause behavioral change, how this information becomes neurobiologically encoded, and the functional consequences of these changes remain fundamental puzzles relevant to diverse fields from evolutionary biology to the health sciences. Here we explore how insects provide unique opportunities for comparative study of developmental behavioral plasticity. Insects have sophisticated behavior and cognitive abilities, and they are frequently studied in their natural environments, which provides an ecological and adaptive perspective that is often more limited in lab-based vertebrate models. A range of cues, …

Sexuality And Borders In Right Wing Times: A Conversation, Alyosxa Tudor, Miriam Ticktin

Publications and Research

We respond to prompts about the relationships between race, migration, and sexuality, as these intersecting differences have been forced into the same frame by the violent practices of right-wing regimes, and brought into relief by Covid19. Even as we have long known that sexual politics are a way to govern bodies, and to distribute uneven states of vulnerability, we are seeing new incarnations of government. What we aim to point out is how people who are seen as “different” are being attacked, maimed, dispossessed and murdered. But perhaps more importantly, we insist on the specific nature of right-wing times because …

Black Maternal Mortality In The United States, Grace Phelps

Honors College Theses

Black maternal mortality is a looming issue in the United States as the rate of Black maternal deaths is 3-4 times higher than the average rate for White women. Research establishes that this is a multifaceted issue of care quality, preexisting health, biases and racism, and structural inequalities. This study aims to discuss the statistics, contributing factors, and possible solutions to the issue of Black maternal mortality. Specifically, this study aims to educate nursing students on the matter and test the implications an educational session has on knowledge about Black maternal mortality and how health care professionals can be part …

Indian Contribution In Animal Cell Diseases: A Scientometric Mapping Of Research Publications, Surulinathi Muthuraj, Rajkumar N Research Scholar, Arputha Sahaya Rani Y Research Scholar, Srinivasaragavan S Professor, Jayasuriya T Final Year M.L.I.Sc

Library Philosophy and Practice (e-journal)

This study evaluates the Indian Animal Cell Diseases research output during 1989–2021. We have made a Scientometric analysis of contribution from India in leading journals, international collaboration of publications, most productive Institutions, most productive authors and highly cited works. The study uses 32 years (1989– 2021) publications data in Animal Cell Disease drawn from Web of Science international multidisciplinary bibliographical database. Animal Cell Diseased share of 1741 Publications are collaboration with 75 countries and registered 38345 Citations. Publications and Citations are increased rapidly during the study period, and most notably in the 2013 to 2020. In total, there were 1741 …

Covid-19, Science, And Race: A Black Pentecostal Engagement, David Daniels

Spiritus: ORU Journal of Theology

A Black Pentecostal engagement of COVID-19, science, and race points towards a rapport between the Spirit-empowered Movement and health sciences where religious and secular (science) actors are respected agents in the public arena with each offering valuable perspectives and resources to pivotal conversations about public health in this case. In this article, it is argued that the Church of God in Christ (COGIC) represented in the episcopal letters of Bishop Charles E. Blake, Sr., the presiding bishop of COGIC from 2007 to 2021, demonstrate a religious perspective that possesses a critical perspective on engaging health science during the COVID-19 pandemic. …

Cxcl11 And Smica As Predictive Biomarkers For Efficacy Of Anti-Ctla4 Immunotherapy, Keith Sadoon Bahjat, Helena Maria Hoen, Yoshinobu Koguchi, Alan J. Korman

Technology Transfer - Patents

Provided herein are methods for selecting a cancer patient for anti-CTLA-4 immunotherapy, or predicting whether a cancer patient will respond to anti-CTLA4 immunotherapy, based on measured levels of CXCL1 1 and/or sMICA. Such methods are useful for determining whether an anti-CTLA-4 immunotherapy is likely to improve overall survival of a cancer patient. Also provided herein are methods of treating a cancer patient with an anti-CTLA-4 immunotherapy, wherein the patient is first tested for levels of CXCL1 1 and/or sMICA. Also provided are methods for treating a cancer patient with a CXCL1 1 antagonist or sMICA ant agonist alone, or in …

“Can You Make It Out Alive?” Investigating Penal Imaginaries At Forts, Sanitaria, Asylums, And Segregated Schools, Linda Mussell, Kevin Walby, Justin Piché

Qualitative Criminology (QC)

"We draw from literature on penal imaginaries to examine representations at fright nights and other staged cultural scenes from across Canada and the United States that reproduce justifications for imprisonment and punishment. Based on an analysis of online content and news coverage of fright nights organized at forts, sanitoria, psychiatric institutions/asylums, and segregated schools, we demonstrate that these displays mobilize stereotypes and shame to denigrate prisoners and naturalize imprisonment. Moreover, we show that these displays invoke health tropes concerning contagion to intensify fears regarding prisoners by portraying them as a threat to the social body, further rationalizing the existence of …

Cyp2d6 Genetic Variation And Its Implication For Vivax Malaria Treatment In Madagascar, Rajeev K. Mehlotra, Andrea Gaedigk, Rosalind E. Howes, Tovonahary A. Rakotomanga, Arsene C. Ratsimbasoa, Peter A. Zimmerman

Manuscripts, Articles, Book Chapters and Other Papers

Plasmodium vivax is one of the five human malaria parasite species, which has a wide geographical distribution and can cause severe disease and fatal outcomes. It has the ability to relapse from dormant liver stages (hypnozoites), weeks to months after clearance of the acute blood-stage infection. An 8-aminoquinoline drug primaquine (PQ) can clear the hypnozoites, and thus can be used as an anti-relapse therapeutic agent. Recently, a number of studies have found that its efficacy is compromised by polymorphisms in the cytochrome P450 2D6 (CYP2D6) gene; decreased or absence of CYP2D6 activity contributes to PQ therapeutic failure. The …

Covid-19 Newsletter (Vol. 68), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Main Achievements, Challenges, And Recommendations Of Biodiversity Conservation In China, Fuwen Wei, Xiaoge Ping, Yibo Hu, Yonggang Nie, Yan Zeng, Guangping Huang

Bulletin of Chinese Academy of Sciences (Chinese Version)

After nearly 30 years of development, China has basically realized the comprehensive conservation of biodiversity. Biodiversity conservation has been upgraded to a national strategy and incorporated into the top-level design, with laws and regulations gradually being improved and major scientific breakthroughs continuously being achieved. Through the implementation of major biodiversity conservation and ecological restoration projects, establishment of protected area system, and delineation of ecological red line, important ecosystems and endangered species have been effectively protected, and social participation and public awareness have been significantly improved. In addition, by signing a number of biodiversity-related international conventions and agreements and proposing the …

Not-So-Low-Hanging Fruit: Journey From Identifying Hcv To Proving It Pathogen Of Hepatitis C, Xiaofei Fan, Cheng Zhou

Bulletin of Chinese Academy of Sciences (Chinese Version)

The Nobel Prize in Physiology or Medicine 2020 was awarded jointly to Harvey J. Alter, Michael Houghton, and Charles M. Rice for their contributions in the discovery of hepatitis C virus (HCV). However, eight years lapsed between Houghton hunting down the virus in 1989 and Rice proving HCV alone could cause hepatitis in 1997. How did this seemingly low-hanging fruit turn out to take so long? We reviewed literature to piece together studies during those years, and determined contributions by different groups (Rice's group included). Through a close look into its performance at two milestones (determining the 3'-terminal sequence of …