Digital Commons Network^™

Acupuncture For Pain, Julita Mitchell, Md

Department of Family & Community Medicine Presentations and Grand Rounds

Objectives

➢ To introduce basic acupuncture theory and proposed mechanisms.

➢ To describe a typical acupuncture encounter.

➢ To outline the indications for acupuncture.

➢ To explore clinical evidence behind acupuncture for pain
○ Knee osteoarthritis, low back pain, headache

➢ Review AAFP Clinical Recommendations for acupuncture.

➢ To discuss logistical aspects of acupuncture referral.

Maternal Methylmercury Exposure Through Rice Ingestion And Child Neurodevelopment In The First Three Years: A Prospective Cohort Study In Rural China, Sarah E. Rothenberg, Susan A. Korrick, Jihong Liu, Yanfen Nong, Chuan Hong, Eva P. Trinh, Xu Jiang, Fred J. Biasini, Fengxiu Ouyang

Faculty Publications

Background

Rice is an important dietary source for methylmercury; however, rice does not contain the same beneficial nutrients as fish. Our main objective was to assess associations of prenatal methylmercury exposure through rice ingestion with child neurodevelopment in rural China.

Methods

Eligible peripartum women were enrolled (n = 391), provided peripartum hair samples, and children’s neurodevelopment was assessed at 12 months (n = 264, 68%) and 36 months (n = 190, 48%) using the Bayley Scales of Infant Development, 2nd Edition, including the Mental Developmental Index (MDI) and the Psychomotor Developmental Index (PDI). Associations between prenatal methylmercury …

Identification Of A Chlorovirus Pbcv-1 Protein Involved In Degrading The Host Cell Wall During Virus Infection, Irina V. Agarkova, Leslie C. Lane, David D. Dunigan, Cristian F. Quispe, Garry A. Duncan, Elad Milrot, Abraham Minsky, Ahmed Esmael, Jayadri S. Ghosh, James L. Van Etten

Nebraska Center for Virology: Faculty Publications

Chloroviruses are unusual among viruses infecting eukaryotic organisms in that they must, like bacteriophages, penetrate a rigid cell wall to initiate infection. Chlorovirus PBCV-1 infects its host, Chlorella variabilis NC64A by specifically binding to and degrading the cell wall of the host at the point of contact by a virus-packaged enzyme(s). However, PBCV-1 does not use any of the five previously characterized virus-encoded polysaccharide degrading enzymes to digest the Chlorella host cell wall during virus entry because none of the enzymes are packaged in the virion. A search for another PBCV-1-encoded and virion-associated protein identified protein A561L. The fourth domain …

Novel Genetic Mutations In Genes Agbl5 And Tulp1 For Presumed Unilateral Retinitis Pigmentosa Managed With Low Vision Rehabilitation: A Case Report And Review, Maggie Man Ki Ho Od, Ms, Faao, Stephanie Schmiedecke-Barbieri Od, Faao, Abcmo, Dip Low Vision, Patricia C. Sanchez-Diaz Phd, Dvm, Faao, Carolyn E. Majcher Od, Faao, Fors

Optometric Clinical Practice

Background: Retinitis pigmentosa is a group of hereditary retinal diseases characterized by the degeneration of rod and cone photoreceptors. It commonly results in night blindness followed by tunnel vision and central vision reduction. The classic triad of clinical signs includes pigmented bone spicules, waxy disc pallor, and arterial attenuation. Unilateral retinitis pigmentosa is rare and can be supported with ancillary testing including genetic and laboratory studies to rule out differential diagnoses.

Case Report: A 68-year-old Hispanic female was referred to the low vision rehabilitation clinic due to progressive vision loss in the left eye (OS) that began 15 years ago. …

The New (?) Look Of Precaution, Paul B. Freeman Od

Optometric Clinical Practice

Letter from the Editor-in-Chief

2021-04-27_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Book Of Abstracts, Seton Hall University

Petersheim Academic Exposition

No abstract provided.

Phenotype Of Peripheral Nk Cells In Latent, Active, And Meningeal Tuberculosis, José Alberto Choreño-Parra, Shabaana A. Khader, Et Al

Open Access Publications

No abstract provided.

The Anti-Sigma Factor Muca Is Required For Viability In Pseudomonas Aeruginosa, Melissa C. Schofield, Daniela Q. Rodriguez, Amanda A. Kidman, Erin K. Cassin, Lia A. Michaels, Elizabeth A. Campbell, Peter A. Jorth, Boo Shan Tseng

Teaching and Learning Faculty Research

During decades-long infections in the cystic fibrosis (CF) airway, Pseudomonas aeruginosa undergoes selection. One bacterial genetic adaptation often observed in CF isolates is mucA mutations. MucA inhibits the sigma factor AlgU. Mutations in mucA lead to AlgU misregulation, resulting in a mucoid phenotype that is associated with poor CF disease outcomes. Due to its ability to be mutated, mucA is assumed to be dispensable for bacterial viability. Here we show that, paradoxically, a portion of mucA is essential in P. aeruginosa. We demonstrate that mucA is no longer required in a strain lacking algU, that mucA alleles encoding for proteins …

The Analysis Of Folate-Dependent Transcription Factor Zinc Finger Protein 410, Feifan Xu

Senior Honors Theses

A previous study that introduced dietary folate to mice in the form of folic acid to determine if gene activity would be altered based on this biological molecule demonstrated that mice without folic acid had cognition deficits, and this phenomenon was correlated with altered gene expression in their brains. The included bioinformatic analysis revealed two main transcription factors that bind to proteins in the nucleus, and one is known as the Zinc Finger Protein 410 (Zfp410). Due to the lack of literature explaining the function of this transcription factor, this project is intended to analyze Zfp410 in detail from scratch. …

Covid-19 Newsletter (Vol. 69), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Preferred Narratives And Their Impact On Historical Memory: An Examination Through Comparison Of Twentieth Century Pandemics, Renee Semple

Honors Scholar Theses

Societal response to a crisis and the narratives that emerge from the event(s) often vary and oppose one another. A narrative can be considered a point of view or a lens that is often cultivated through experiences and carries its own tone while telling events. This thesis compares the narratives that emerged from both the 1918 and 1957 influenza pandemics. Examining the 1918 influenza pandemic reveals both a public and a private narrative, in which the public narrative is the preferred out of the two. Filled with optimism, the preferred public narrative focused on moving forward and furthering scientific research—a …

Increasing The Frequency Of Periodic Spatial Disturbance Decreases Surface Attachment Protein Expression In Staphylococcus Aureus, Ivana M. Barraza

All HCAS Student Capstones, Theses, and Dissertations

Staphylococcus aureus is an opportunistic pathogen that can cause a variety of acute and chronic illnesses. The severity of these illnesses such as sepsis, necrotizing pneumonia, and toxic shock syndrome is measured through the virulence that S. aureus inflicts on its host. Methicillin-resistant S. aureus (MRSA) is commonly associated with secondary infections and is challenging to treat given the limited selection of antibiotics that are effective against it. Accordingly, novel approaches to reduce S. aureus pathogenicity are required. S. aureus regulates pathogenesis through a cell-to-cell communication system referred to as quorum sensing. Effective communication determines the production of two broad …

Perceptions Of Women, Their Husbands And Healthcare Providers About Anemia In Rural Pakistan: Findings From A Qualitative Exploratory Study, Sumera Aziz Ali, Anam Shahil Feroz, Zahid Abbasi, Savera Aziz Ali, Ahreen Allana, K Michael Hambidge, Nancy F. Krebs, Jamie E. Westcott, Elizabeth M. Mcclure, Robert L. Goldenberg, Sarah Saleem

Community Health Sciences

Background: In Pakistan, there is a dearth of literature on the perceptions of anemia among women of reproductive age (WRA). This study was undertaken to explore the perceptions of women, their husbands, and healthcare providers about anemia, its possible causes, and how anemia impacts maternal and child health in Thatta, Pakistan.
Methods: A qualitative study was conducted in Thatta, Pakistan from September to December 2018. Using a pre-tested semi-structured interview (SSI), we collected data to understand their definitions of anemia through ten focus group discussions (FGDs) with women and their partners and ten primary informant interviews (KIIs) with healthcare providers. …

Infectious Disease Propagation Modeling, Joseph E. Simpson, Joseph S. Overstreet

Linfield University Student Symposium: A Celebration of Scholarship and Creative Achievement

We present several computational models of infectious disease propagation. We discuss both stochastic network models and deterministic differential equations models. The primary focus is on variations of the SIR compartmental differential equations model. We attempt to determine the characteristics of a pandemic that lead to endemic diseases and explore how individual mitigation strategies affect the spread of infectious diseases.

Pre-Departure Training Is Essential For Preparing Healthcare Teams For Service-Learning To Resource-Limited Countries, Suzanne Fox Trotter

Education Collection

Introduction: Limited research exists on effective pre-departure training (PDT) for interprofessional healthcare disciplines participating in international service-learning (ISL), particularly to resource-limited settings.

Method: A convenience sample of 21 physical and occupational therapy students and clinicians who participated in four 1-hour PDT sessions were included in this mixed-methods study. Training consisted of informative, reflective, and simulation experiences to enhance self-awareness, teambuilding, cultural knowledge, and in support of trip preparations. Training session debriefings were transcribed and coded. The Cross-Cultural Adaptability Inventory (CCAITM) was administered pre-training and post-experience.

Results: Qualitative data showed emerging themes around collaboration, mentorship, empowerment, opportunity, preparedness, self-awareness, and confidence …

Highly Branched Polymers Based On Poly(Amino Acid)S For Biomedical Application, Marisa Thompson, Carmen Scholz

PRC-Affiliated Research

Polymers consisting of amino acid building blocks continue to receive consideration for biomedical applications. Since poly(amino acid)s are built from natural amino acids, the same building blocks proteins are made of, they are biocompatible, biodegradable and their degradation products are metabolizable. Some amino acids display a unique asymmetrical AB2 structure, which facilitates their ability to form branched structures. This review compares the three forms of highly branched polymeric structures: structurally highly organized dendrimers, dendrigrafts and the less organized, but readily synthesizable hyperbranched polymers. Their syntheses are reviewed and compared, methods of synthesis modulations are considered and variations on their traditional …

Highly Branched Polymers Based On Poly(Amino Acid)S For Biomedical Application, Marisa Thompson, Carmen Scholz

PRC-Affiliated Research

Polymers consisting of amino acid building blocks continue to receive consideration for biomedical applications. Since poly(amino acid)s are built from natural amino acids, the same building blocks proteins are made of, they are biocompatible, biodegradable and their degradation products are metabolizable. Some amino acids display a unique asymmetrical AB2 structure, which facilitates their ability to form branched structures. This review compares the three forms of highly branched polymeric structures: structurally highly organized dendrimers, dendrigrafts and the less organized, but readily synthesizable hyperbranched polymers. Their syntheses are reviewed and compared, methods of synthesis modulations are considered and variations on their traditional …

The Health Of Haitian Schoolchildren: Longitudinal Effect Of Annual Visits On Growth, Jamarie Geller, Mary Starrs, Andrew Bartholomew, Sara Kaliszak, Jeri Kessenich

Journal of Refugee & Global Health

Objectives: Haiti has one of the highest rates of childhood undernutrition in the world, devastating overall health. This study focuses on the growth of children offered longitudinal healthcare by Kids Health for Haiti, using BMI to indicate developmental and nutritional status. Objectives include collecting baseline prevalence data, examining the longitudinal impact of longitudinal interventions, and discussing future investigation and programming areas.

Methods: A retrospective longitudinal observational chart review on 245 students over a six-year period analyzing height, weight, and BMI. All data was collected as part of routine health provision and underwent statistical analysis using a single-subject design.

Results:46.3%, …

2021 Schedule Of Events, Seton Hall University

Petersheim Academic Exposition

No abstract provided.

Streptococcus Anginosus Lung Infection And Empyema: A Case Report And Review Of The Literature, Nishita Tripathi, Kuldeep Ghosh, Anupama Raghuram

The University of Louisville Journal of Respiratory Infections

Streptococcus milleri group (SMG) also referred to as the Streptococcus anginosus group. These are Gram-positive, variable hemolysis, catalase negative, microaerophilic, non-motile facultative anaerobes which have been known to cause abscesses in humans. We report a case of empyema caused by Streptococcus anginosus in a patient with an unresolved pneumonia for over a month. In early October 2018, the patient presented to an emergency room with the complaints of shortness of air, productive cough, chills, subjective fever and weight loss for 4 weeks. A chest X-ray revealed a left lower lobe pneumonia. He was treated with 250 mg of azithromycin for …

2021-04-26_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

S.O.S. For Covid-19 (Subjective And Objective Screening): Are Asymptomatic Cases Truly Without Warning Signs?, Nathan Hughes

Honors College Theses

This study investigates the usefulness of five objective signs, evaluates relationships between objective signs with symptoms of COVID-19, and assesses the accuracy of ambient forehead temperature with tympanic temperature. Data were collected at Wayne State University. Blood oxygen levels and blood pressure were measured via pulse oximeters and blood pressure cuff. Body temperature was measured with a thermometer via the temple and the forehead. Smell was tested with two scented markers. None of the 29 participants confirmed a positive COVID-19 test. Therefore, only relationships between vital sign measurements were reported. No significant correlations were revealed upon analysis. Infrared and temporal …

Use Of Probiotic In Preventing Antibiotic-Associated Diarrhea, Chanda Amatya

MSN Capstone Projects

Antibiotic-associated diarrhea (AAD) including Clostridium difficile associated diarrhea (CDAD) has been a challenging topic for the healthcare industry. AAD is caused by the disruption of normal microbial balance along with the gastrointestinal (GI) tract due to the use of an antibiotic. AAD not only increases healthcare cost burden but also increases morbidity and mortality among vulnerable populations such as the elderly. Death from CDAD for a patient over 65 years is about 90% (Mallina et al., 2018). Antibiotic use is very common among the elderly and it is the responsibility of healthcare providers to take appropriate measures in preventing complications …

275— The Effects Of Social Behavior And Its Relation To Covid-19 In The State Of New York, Emily Mcneil, Sedar Ngoma

GREAT Day Posters

When COVID-19 first reached the United States the virus impacted the various states differently. By determining the initial rate of increase of the disease for each state, the basic reproduction number, can be used to determine how contagious the disease is. The basic reproduction number, denoted as $\mathcal{R}_0$, is the average number of secondary cases produced by one infectious individual in an entirely acceptable population. Using the $\mathcal{R}_0$ value determined from data collected from the state of New York, we construct SIR/SEIR models to quantify the effects of social behavior, like social distancing and wearing masks, and the relation to …

Exploring Community Health Worker Roles, Support, And Experiences In The Context Of The Covid-19 Pandemic In Kenya, Frontline Health Project

Reproductive Health

This brief presents quantitative results from a mixed-methods study conducted by Population Council Kenya which explores the experiences and roles of community health workers (CHWs) during COVID-19. The results indicate that CHWs are carrying out their routine work at higher levels, with increased responsibilities due to COVID-19.

Psychiatric Symptoms, Risk, And Protective Factors Among University Students In Quarantine During The Covid-19 Pandemic In China (Vol 17, 15, 2021), Shufang Sun, Simon B. Goldberg, Danhua Lin, Shan Qiao, Don Operario

Faculty Publications

Background

The COVID-19 pandemic has made unprecedented impact on the psychological health of university students, a population vulnerable to distress and mental health disorders. This study investigated psychiatric symptoms (anxiety, depression, and traumatic stress) during state-enforced quarantine among university students in China (N = 1912) through a cross-sectional survey during March and April 2020.

Results

Psychiatric symptoms were alarmingly prevalent: 67.05% reported traumatic stress, 46.55% had depressive symptoms, and 34.73% reported anxiety symptoms. Further, 19.56% endorsed suicidal ideation. We explored risk and protective factors of psychological health, including demographic variables, two known protective factors for mental health (mindfulness, perceived …

215— Schistosomiasis Infections In School Aged Children In Ghana, Katerina Pisciotta, Maia Mazzaferro

GREAT Day Posters

Schistosomiasis is a Neglected Tropical Disease caused by a parasitic blood fluke. There are currently over 240 million people affected globally. Humans become infected after coming into contact with water containing the infectious stage of the parasite. Our data consists of egg counts for Schistosoma haematobium and Schistosoma mansoni collected from school-aged children in Tomefa, Ghana, a marginalized informal community, between 2014 and 2019. Our research explores whether or not reinfections and continuous infections were occurring over the six-year period. Although the government conducts periodic mass drug administration, reinfections are likely given the social and environmental conditions in the community. …

076— Geneseo Covid 19 Study Group Report Ii: Infection Mechanism And Methods Of Prevention, Joshua Thomas, Kazushige Yokoyama, Mir Ali, Rachel Hirschkind

GREAT Day Posters

The SARS-CoV-2 virus is spread by infected individuals exhaling aerosols that contain active virus cells that are inhaled by another person or land on high-contact surfaces. Once the virus is inhaled, the angiotensin-converting enzyme 2 (ACE2) protein on the lung cells functions as a receptor for the SARS-CoV-2 virus. ACE2 normally converts angiotensin II (ANG II), a protein that is harmful to the lungs, into another molecule that counteracts the effects of ACE2. When ACE2 is occupied with SARS-CoV-2, ANG II will not be converted, resulting in damage to the lungs. Distancing six feet apart has become a standard guideline …

352— Investigating The Function Of Mhc Class I In Xenopus Laevis Tadpoles, Stephanie Alvarez Merlos, Annika Mounts

GREAT Day Posters

Xenopus laevis, is an excellent model organism for transgenesis and immunological research due to their large eggs and the similarities between mammalian and amphibian immune systems. MHC Class I is found on nearly all cells and educates T cells to recognize between self and non-self which is an essential immune system function. However, tadpoles don’t have detectable MHC Class I expression while adult frogs do. Despite this tadpoles are still immunocompetent; thus the role of MHC Class I in tadpoles is unknown. To investigate MHC Class I function we inactivated the corresponding gene in Xenopus laevis using CRISPR/Cas9. The …