Digital Commons Network^™

The Awakening: The Impact Of Covid-19, Racial Upheaval, And Political Polarization On Black Women Lawyers, Tsedale M. Melaku

Fordham Law Review

No abstract provided.

Bighorn Sheep Demographics Following Pneumonia Die-Off Events, Kylie Sinclair

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Bighorn sheep populations across the Intermountain West are subject to disease pressure from the respiratory bacteria Mycoplasma ovipneumoniae. Although the effects of M. ovipneumoniae-associated disease die-offs are well documented, less is known about the factors driving long-term differences in post-die-off population responses. While many herds experience years to decades in which recruitment is less than 20 lambs per 100 ewes, some herds’ lamb survival rates are able to rebound rapidly following die-off events. The reason why these herds recover quickly while others do not is currently unknown. Here, we assess the roles environmental, demographic, and pathogen-associated factors could …

The Effects Of Differences In Vaccination Rates Across Socioeconomic Groups On The Size Of Measles Outbreaks, Elizabeth Hunter, John D. Kelleher

Conference papers

Vaccination rates are often presented at the level of a country or region. However, within those areas there might be geographic or demographic pockets that have higher or lower vaccination rates. We use an agent-based model designed to simulate the spread of measles in Irish towns to examine if the effectiveness of vaccination rates to reduce disease at a population level is sensitive to the uniformity of vaccinations across socioeconomic groups. We find that when vaccinations are not applied evenly across socioeconomic groups we see more outbreaks and outbreaks with larger magnitudes.

Pandemic Emotions: The Extent, Correlates And Mental Health Consequences Of Personal And Altruistic Fear Of Covid-19, Melissa M. Sloan, Murat Haner, Amanda K. Graham, Francis T. Cullen, Justine T. Pickett, Cheryl L. Jonson

Criminal Justice & Criminology: Faculty Publications

COVID-19 has had unprecedented effects on populations around the world. Given the political context of the pandemic and the nation’s response to it, this study sought to assess the extent of Americans’ personal fear about the virus as well as their fear for others (altruistic fear), identify potential predictors of these fears, and examine the mental health impact of heightened COVID-19 fears. Overall, a majority of respondents worried about various aspects of the virus, from being exposed to dying, and reported often worrying about others, including family, the elderly, and healthcare professionals. Building on the fear of crime literature, we …

Implications Of The Evolutionary Past On The Activities Of Virb: A Key Transcriptional Regulator Of Virulence Genes In Shigella Flexneri, Jillian Nicole Socea

UNLV Theses, Dissertations, Professional Papers, and Capstones

Shigella species are bacterial agents that are the leading cause of diarrheal diseases, the second leading cause of child mortality worldwide. One key protein in Shigella is VirB, a transcriptional regulator of virulence genes that is essential for pathogenicity. VirB functions to antagonize H-NS, a histone-like nucleoid structuring protein that silences many genes found on the large virulence plasmid (pINV). The interplay between H-NS, the silencer, and VirB, the anti-silencer, is fundamental for Shigella virulence. Furthermore, this mechanism of gene regulation appears widespread in many bacteria including other enteric pathogens.

The goal of my dissertation was to explore the activities …

Global Trends In Norovirus Genotype Distribution Among Children With Acute Gastroenteritis., Jennifer L. Cannon, Joseph Bonifacio, Filemon Bucardo, Javier Buesa, Leesa Bruggink, Martin Chi-Wai Chan, Tulio M. Fumian, Sidhartha Giri, Mark D. Gonzalez, Joanne Hewitt, Jih-Hui Lin, Janet Mans, Christian Muñoz, Chao-Yang Pan, Xiao-Li Pang, Corinna Pietsch, Mustafiz Rahman, Naomi Sakon, Rangaraj Selvarangan, Hannah Browne, Leslie Barclay, Jan Vinjé

Manuscripts, Articles, Book Chapters and Other Papers

Noroviruses are a leading cause of acute gastroenteritis (AGE) among adults and children worldwide. NoroSurv is a global network for norovirus strain surveillance among children(genotype and polymerase type) and uploaded 1,325 dual-typed sequences to the NoroSurv web portal during 2016-2020. More than 50% of submitted sequences were GII.4 Sydney[P16] or GII.4 Sydney[P31] strains. Other common strains included GII.2[P16], GII.3[P12], GII.6[P7], and GI.3[P3] viruses. In total, 22 genotypes and 36 dual types, including GII.3 and GII.20 viruses with rarely reported polymerase types, were detected, reflecting high strain diversity. Surveillance data captured in NoroSurv enables the monitoring of trends in norovirus strains …

Sentiment Analysis Of Covid-19 Pandemic On The Stock Market, Prajwal Eachempati, Praveen Ranjan Srivastava, Prabin Kumar Panigrahi

American Business Review

COVID-19 is a dreadful infectious disease, morphed into an economic crisis causing extensive and longstanding ramifications across global markets. Investors continue to hear about COVID-19 and its impact in one corner of the globe or the other for a long time. Though the effects of COVID19 started in December 2019 in Wuhan, China, global markets did not respond actively till W.H.O officially declared on March 11, 2020, that the COVID19 outbreak is a global pandemic. These multi-channel events have eroded investor sentiment, tanking the global stock markets. This article uses a machine learning approach to Twitter to analyze and follow …

The Days After Covid-19: A Meta-Analysis On The Impact Of Epidemics And Pandemics On Long-Term Macro-Economic Performance, Maria Klona

American Business Review

During the COVID-19 pandemic, the future of the global economies appears gloomy as policy, industry and academia stakeholders assess the immediate adverse effects. This research meta-analysis studies on the impact of epidemics and pandemics on the longer-term performance of national economies covering the past 30 years. The findings indicate that the impact of pandemics on economies for periods of over two years might move from the immediate adverse effects to small positive effects. Several moderators were found to affect this relationship, including socio-economic and methodological factors. The findings agree with a significant amount of existing literature and are in line …

How Covid-19 Has Fundamentally Changed Clinical Research In Global Health, Jay J H. Park, Robin Mogg, Gerald E. Smith, Etheldreda Nakimuli-Mpungu, Fyezah Jehan, Craig R. Rayner, Jeanine Condo, Eric H. Decloedt, Jean B. Nachega, Gilmar Reis, Edward J. Mills

Department of Paediatrics and Child Health

COVID-19 has had negative repercussions on the entire global population. Despite there being a common goal that should have unified resources and efforts, there have been an overwhelmingly large number of clinical trials that have been registered that are of questionable methodological quality. As the final paper of this Series, we discuss how the medical research community has responded to COVID-19. We recognise the incredible pressure that this pandemic has put on researchers, regulators, and policy makers, all of whom were doing their best to move quickly but safely in a time of tremendous uncertainty. However, the research community's response …

Urgently Seeking Efficiency And Sustainability Of Clinical Trials In Global Health, Jay J H. Park, Rebecca F. Grais, Monica Taljaard, Etheldreda Nakimuli-Mpungu, Fyezah Jehan, Jean B. Nachega, Nathan Ford, Denis Xavier, Andre P. Kengne, Zulfiqar Ahmed Bhutta

Department of Paediatrics and Child Health

This paper shows the scale of global health research and the context in which we frame the subsequent papers in the Series. In this Series paper, we provide a historical perspective on clinical trial research by revisiting the 1948 streptomycin trial for pulmonary tuberculosis, which was the first documented randomised clinical trial in the English language, and we discuss its close connection with global health. We describe the current state of clinical trial research globally by providing an overview of clinical trials that have been registered in the WHO International Clinical Trial Registry since 2010. We discuss challenges with current …

Prevalence And Reasons Of Increased Type 2 Diabetes In Gulf Cooperation Council Countries, Mohammed Z. Aljulifi

Saudi Medical Journal

Arab Gulf Cooperation Council countries are considered as one of the most regions exhibiting a high prevalence of diabetes including the kingdom of Saudi Arabia, Bahrain, Qatar, Oman, Kuwait, and United Arab of Emirates, which have similar population characteristics (for example, religion, language, lifestyle, diet, and income). The frequency rate of diabetes in these countries ranged from 8 to 22% according to the last International Diabetes Federation (IDF) report. Many factors impact the prevalence in this region including obesity, unhealthy lifestyle, increased life expectancy, increased healthcare expenditures, increased the incidence of type 2 diabetic mellitus (T2DM) among children and young …

Food Selection And Consumption During The Covid-19 Pandemic/Quarantine, Shawnyse Debaun, Pui Tan Lau

Loma Linda University Research Reports

Background: The Coronavirus disease 2019 (COVID-19) created an unexpected outbreak that led to a pandemic and the fear of scarcity regarding food. Due to those who shopped in panic, grocery stores began to limit the number of specific items purchased per family. The COVID-19 is a novel disease that has changed society by wearing face-coverings when out in public, temporarily closing indoor dining at restaurants, and converting schools online. The over-purchase of toilet paper and water caused many grocery and department stores to exhaust their inventory. This situation may have instilled fear of scarcity and leave to the over-purchase …

The Cases They Carry : A Narrative Analysis Of Crisis Counselors Working In Behavioral Health Emergency Settings, Rachel E. Sugerman

Theses, Dissertations and Culminating Projects

Utilizing a qualitative approach informed by narrative inquiry, this study considered the ways in which eight crisis counselors working in behavioral health emergency settings make meaning of their experiences. Participant narratives focused on the intense, multidimensional, and often emotionally demanding nature of crisis work, something they understood to be inherent to working within these settings. The findings revealed that these crisis counselors often felt isolated, unsupported, and unprepared for their positions, leaving them to negotiate the demands of the work and to make meaning of their experiences on their own. Participants developed various methods of coping, yet these techniques were …

A Web Application To Disseminate Repatriation And Travel Information About African Countries, Daniel Otuo-Acheampong

Theses, Dissertations and Culminating Projects

Africa is a continent with incredibly diversified cultures, landscapes, and people. Due its vastness, it can be difficult to assess accurate travel related information about African countries. The purpose of this project is to build a website that will serve as an African destination information insider. African countries are drawing people from all around the world, and this is evident in the formulation of initiatives to attract people to the continent during the past decade. Prime examples of these initiatives include Ghana’s Year of Return initiative and Nigeria’s door of return. This project, that entails the design and development of …

Impact Of Covid-19 On Residential Waste Streams Of Montclair Township, Jeanne Huguette Perrine

Theses, Dissertations and Culminating Projects

The COVID-19 pandemic has been found to have numerous impacts on day-to-day life, everywhere around the globe. One important sector which is particularly being affected is the waste management sector. Reports from the Solid Waste Association of North America (SWANA) showed possible variations in the source and volume of solid waste generated due to the enforcement of lockdown by the authorities to contain the coronavirus outbreak (Kulkarni & Anantharama, 2020). Food waste specifically is one of the most discussed topics in the world nowadays. About one-third of the food produced for humans ends up in the trash (Nusaka, 2020). It …

I Matter: Understanding The Self-Care Practices Of School Counselors During The Covid-19 Pandemic And How Internal And External Factors Create Barriers, Alisha Rene Marie Jones

Graduate Theses and Dissertations

Diminished self-care practices and heightened stress of school counselors is a continuing problem in education. With role ambiguity, high student-to-counselor ratios, emotional exhaustion, and others adding pressure to the roles and responsibilities of school counselors, this study investigated the self-care practices of Missouri school counselors and the internal and external factors which influence them, specifically within the context COVID-19. Clayton Alderfer’s (1972) Existence, Relatedness, and Growth theory was used as a theoretical framework for chosen self-care practices represented in this study and was supported by Robert Kegan’s and Lisa Lahey’s (2009) Immunity to Change theory to understand the competing commitments …

Hepatitis C Elimination Among People Incarcerated In Prisons: Challenges And Recommendations For Action Within A Health Systems Framework, Matthew J. Akiyama, Nadine Kronfli, Joaquin Cabezas, Yumi Sheehan, Prem H. Thurairajah, Richard Lines, Andrew R. Lloyd, International Network On Health And Hepatitis In Substance Users–Prisons Network

Project ECHO Bibliography

Hepatitis C virus (HCV) is a global public health problem in correctional settings. The International Network on Health and Hepatitis in Substance Users–Prisons Network is a special interest group committed to advancing scientific knowledge exchange and advocacy for HCV prevention and care in correctional settings. In this Review, we highlight seven priority areas and best practices for improving HCV care in correctional settings: changing political will, ensuring access to HCV diagnosis and testing, promoting optimal models of HCV care and treatment, improving surveillance and monitoring of the HCV care cascade, reducing stigma and tackling the social determinants of health inequalities, …

Publication Study Of Liquid Crystals In International Perspective: A Scientometric Approach, Dr Padmavathi N, Dr Nayana J

Library Philosophy and Practice (e-journal)

The purpose of this paper is to identify the worldwide scientific publications of Liquid Crystal's research and a significant rising thrust area that has huge potential to improve information understanding, organization, decision making and administration. This study retrieved scholarly communications published during 1999-2019, which are available on the Web of Science. The scientometric analysis performed from global output characteristics, institutional, core journals, continental, countries/territories and topical aspects. International publications' features identified that Liquid crystal research has improved stage and colossal participation and collaboration. The vast research papers were published in 2018. This is the first study to evaluate global literature …

A Scientometric Analysis And Visualization Mapping Of Convalescent Plasma Therapy, Iranna M. Shettar, Gururaj S. Hadagali

Library Philosophy and Practice (e-journal)

This paper deals with the scientometric analysis of the scholarly literature on Convalescent Plasma Therapy, or simply Plasma Therapy, indexed in the SCOPUS database from its first publication to 2020. In this study, 1,722 bibliographic records were analysed, published in 545 journals by 9491 authors from 6046 organizations located in nearly 175 countries. The results showed a sudden increase in the number of publications in 2020 because of the clinical trials due to the COVID-19 pandemic. During the period, an inconsistent trend of publications and the annual growth rate is observed. The average Degree of Collaboration calculated for the overall …

Comparative Analysis Of The Intestinal Bacterial Communities In Mud Crab Scylla Serrata In South India, Elina Apine, Praveen Rai, Madhu K. Mani, Vikram Subramanian, Indrani Karunasagar, Anna Godhe, Lucy M. Turner

School of Biological and Marine Sciences

No abstract provided.

The Impact Of Oxygen Availability And Oxidative Stress On Regulation Of Cyclic-Dimeric-Gmp In Listeria Monocytogenes Strain F2365, Anna G. Welch

Honors Theses

Listeria monocytogenes is a gram-positive foodborne pathogen that results in the infectious disease listeriosis. The second messenger molecule cyclic-dimeric-GMP has been found to be responsible for the regulation of expression of many of its virulence factors with diguanylate cyclases and phosphodiesterases regulating the intracellular concentration of cyclic-di-GMP through synthesis and degradation, respectively. This study investigated the possibility that the availability of oxygen is the environmental signal crucial to the regulation of these enzymes. Prior research in our laboratory has demonstrated that the intracellular concentration of cyclic-di-GMP is elevated when exposed to anaerobic conditions. Due to this, it was hypothesized that …

Leadership, Job Stress And Uncertainty Among Nurses During The Covid-19 Pandemic: Impacts And Implications In Lieu Of Pertinent Theoretical Constructs, Davis Woodson

Honors Theses

The purpose of this study is to determine the effect of the COVID-19 pandemic on practicing nurses in the United States. The study considered the effect of communication, self-efficacy, intolerance to uncertainty, and life satisfaction on nurses’ job satisfaction; additionally, this study considered the extent to which nurses perceived organizational response efficacy was predicted by their perceptions of communication and perceived threat susceptibility. A total of 191 nurses participated in the online survey. The study revealed that life satisfaction was positively predicted by communication, self-efficacy, and life satisfaction in multiple regression analyses. Perceived communication positively predicted perceived organizational response efficacy …

Sodium Pyruvate Ameliorates Influenza A Virus Infection In Vitro And In Vivo, Jessica M. Reel

Graduate Theses/Dissertations

Pyruvate is produced in duplicate at the end of glycolysis in addition to ATP and NADH. Pyruvate is the metabolite of choice in most cells, whether obtained exogenously or endogenously. Recently we found that the addition of pyruvate’s conjugate base, sodium pyruvate, to cell culture media dampened the immune response to influenza A virus (IAV) infection in cultured innate immune cells. Thus, I decided to investigate the mechanism and potential for treatment of IAV. In vitro using bone marrow derived macrophages that were infected with IAV we found that adding sodium pyruvate to the media decreased immune signaling pathways through …

Spirulina Platensis Inclusion Reverses Circulating Pro-Inflammatory (Chemo)Cytokine Profiles In Broilers Fed Low-Protein Diets, Garrett J. Mullenix, Elizabeth S. Greene, Nima K. Emami, Guillermo Tellez-Isaias, Walter G. Bottje, Gisela F. Erf, Michael T. Kidd Jr., Sami Dridi

Poultry Science Faculty Publications and Presentations

Proteins are considered the most expensive nutrients in commercial modern broiler production, and their dietary inclusion at low levels is pivotal to minimize feed costs and reduce nitrogen waste. The quest for an environmentally friendly source of proteins that favor the formulation of low protein diets without compromising broiler health, welfare, and growth performance has become a hotspot in nutrition research. Due to its high protein content, the naturally growing Spirulina microalgae is considered a promising nutrient source. The purpose of the present study was, therefore, to determine the effects of Spirulina supplementation on liver bacterial translocation, hematological profile, and …

Population Genomics Of Invasive Rodents On Islands: Genetic Consequences Of Colonization And Prospects For Localized Synthetic Gene Drive, Kevin P. Oh, Aaron B. Shiels, Laura Shiels, Dimitri V. Blondel, Karl J. Campbell, J. Royden Saah, Alun L. Lloyd, Paul Q. Thomas, Fred Gould, Zaid Abdo, John R. Godwin, Antoinette J. Piaggio

United States Department of Agriculture Wildlife Services: Staff Publications

Introduced rodent populations pose significant threats worldwide, with particularly severe impacts on islands. Advancements in genome editing have motivated interest in synthetic gene drives that could potentially provide efficient and localized suppression of invasive rodent populations. Application of such technologies will require rigorous population genomic surveys to evaluate population connectivity, taxonomic identification, and to inform design of gene drive localization mechanisms. One proposed approach leverages the predicted shifts in genetic variation that accompany island colonization, wherein founder effects, genetic drift, and island-specific selection are expected to result in locally fixed alleles (LFA) that are variable in neighboring nontarget populations. Engineering …

Monitoring Of The Living Conditions Of People With Disabilities In Ukraine Under The Conditions Of The Covid-19 Pandemic (On The Example Of Evangelical Christian Baptists), Olga Polumysna

Occasional Papers on Religion in Eastern Europe

The article finds that the Covid-19 pandemic has significantly affected social relations and exacerbated the already vulnerable situation of people with disabilities. Everything that was hidden or veiled in relation to people with disabilities by society has fully manifested. In these conditions it is necessary to monitor the living conditions of people with disabilities as the most vulnerable category of the population, which are currently ignored because healthy people suffer and are usually put first. The social and medical spheres proved to be the most unstable in the conditions of the pandemic in terms of assistance to vulnerable groups of …

Suppression Of Inflammation Of Cytokine Following Induced Francisella Tularensis Infection, Nicole Renee Setzu

Open Access Theses & Dissertations

Francisella tularensis is intracellular bacteria which is the causative agent of the disease Tularemia. Highly virulent in both humans and animals, it takes only as few as 10 microorganisms to cause a lethal infection. The bacteria can enter via direct or indirect routes causing the activations of the host innate inflammatory response to ensue. The bacteria invade host dendritic cells and neutrophils but predominately macrophages. This causes a mass inflammatory response resulting in the cytokine storm. Activation of Natural Killer T (NKT) cells has been shown to suppress inflammation in in vivo studies. Development and optimization of an in vitro …

Acquired Aorto-Atrial Fistula From Intravenous Drug Use With Underlying Congenital Heart Disease., Mohamed Tashani, Laura Given, Emhemmid Karem, Mahmoud Abualayem

Marshall Journal of Medicine

The development of an aorta-atrial fistula secondary to mechanical aortic valve infective endocarditis, is a rare, serious complication. The fistula is an aberrant intra-cardiac shunt that occurs between the aorta and either the left or right atrium.

An aorta-atrial fistula can be congenital or acquired. In the case of infective endocarditis, the infection’s expansion beyond the valvular structure, may result in an aorto-cavitary fistula (ACF or AAF) with an estimated incidence of 1-2% (1). No clinical trials have been conducted for the best approach of management for this condition. Therefore, treatment strategies are applied to a case-by-case basis by expert …

Zoologists On The Move: Mga Karanasan, Hamon, At Motibasyon Ng Mga Zoologists Edad 25-50 Sa Metro Manila, Eunice Gabrielle A. Galimpin, Natalie Teresita Romualdez

DLSU Senior High School Research Congress

Ang pananaliksik na ito ay tungkol sa danas ng mga zoologists sa Metro Manila. Binigyang pansin dito ang pangkalahatang danas, hamon, at motibasyon ng mga kalahok. Ang pananaliksik ay isinagawa gamit ang penomenolohikal na disenyo ng pag-aaral. Pinili ang labing-isang (11) kalahok gamit ang Purposive Sampling. Bumuo rin ng Patnubay na Talatanungan na naglalaman ng dalawampung (20) tanong na ginamit sa isinagawang pakikipanayam. Batay sa pagsusuri ng mga mananaliksik, nakita na ang mga karaniwang karanasan ng mga zoologists ay ang pagsasagawa ng mga eksperimento sa field site o

laboratoryo, ang paggawa at pagbabahagi ng mga pananaliksik nila, at pagtuturo sa …

Tuberculoid Leprosy Masquerading As Erythema Induratum, Manuel Britto, Danish M. Siddiq, Michael Morgan, Anthony Dedea, Utpal Patel

HCA Healthcare Journal of Medicine

Introduction

Erythema Induratum (EI) is a relatively rare dermatologic disorder affecting subcutaneous fat tissue, which is often associated with Mycobacterium tuberculosis. This report details the presentation, diagnosis and management in a 70-year-old female who presented with a painful erythematous annular rash at the clinic. The rash was later diagnosed as EI associated with Mycobacterium leprae, one rarely seen in literature.

Discussion

EI is a rare form of panniculitis that typically presents as a recurrent grouping of tender nodules and plaques on the posterior aspect of the lower legs. Although EI is considered idiopathic in most cases, it can be associated …