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2021-06-19_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

A Feverish Spring: A Comparative Analysis Of Covid-19 News Framing In Sweden, The Uk, And Egypt, Hend Abdelgaber Ahmed El-Behary

Theses and Dissertations

Based on framing and the social responsibility theoretical frameworks, this comparative study analyzes the dominance of frames in the media coverage of the COVID-19 global pandemic across three countries that have adopted different preventative measures: Sweden (herd immunity) the United Kingdom (full lockdown) and Egypt (partial lockdown ‘curfew’). While several studies have investigated the media’s role during COVID-19, few have analyzed the frames used by the media. The analyses that were made here, for the most part, is on individual countries. The current study bridges a gap by using a comparative approach to interpret the frames discovered in news articles …

Social Determinants Of Health Screening And Preventive Care: A Survey To Assist In Linking Patients To Community Resources In Payson, Utah, Gabriel Ghanadan

Undergraduate Honors Theses

A survey was conducted to screen for social factors that may negatively affect the health of patients being seen by physicians at the Revere Health Family Medicine Clinic in Payson, Utah. Patients who expressed the need for local community services and resources were referred to these services by researchers via phone after physicians were consulted. Out of 690 individuals who visited the clinic between November 11 to December 2, 2019, the survey was administered to and filled out completely by 169 patients. Demographic information on participants was not collected to reduce response time and encourage participation. One hundred and twelve …

Sars-Cov-2 E Gene Variant Alters Analytical Sensitivity Characteristics Of Viral Detection Using A Commercial Reverse Transcription-Pcr Assay, Stephen Tahan, Bijal A Parikh, Lindsay Droit, Meghan A. Wallace, Carey-Ann D Burnham, David Wang

Open Access Publications

Diagnostic assays for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are essential for patient management, infection prevention, and the public health response for coronavirus disease 2019 (COVID-19). The efficacy and reliability of these assays are of paramount importance in both tracking and controlling the spread of the virus. Real-time reverse transcription-PCR (RT-PCR) assays rely on a fixed genetic sequence for primer and probe binding. Mutations can potentially alter the accuracy of these assays and lead to unpredictable analytical performance characteristics and false-negative results. Here, we identify a G-to-U transversion (nucleotide 26372) in the SARS-CoV-2 E gene in three specimens …

Undiagnosed And Untreated Disease Identified In Rural South Africa, Public Relations

Browse All News

No abstract provided.

Educational Intervention On Rheumatic Heart Disease In Samoa, Linda Loyda Ida Tovar

Undergraduate Honors Theses

This paper reviews the impact of rheumatic heart disease (RHD) in Samoa and assesses the effectiveness of a caregiver education intervention by using data collected during the 2019 Rheumatic Relief Program trip. A pre- and post- survey collection tool was used to evaluate the effectiveness of current educational efforts among Samoan child caregivers. Dr. Richard Gill and Dr. Lori Allen, who are both BYU Department of Biology professors and Rheumatic Relief directors, participated in the creation of this program evaluation and completion. This project aims to assess the current caregiver education intervention program used in Rheumatic Relief and provide clear …

Covid-19 And Nursing: A Scientometric Mapping Of Global Literature During 2020-2021, Surulinathi Muthuraj, Jayasuriya T., Srinivasaragavan S., Rosaline Mary A.

Library Philosophy and Practice (e-journal)

The main aim of this paper is to analyze the global Covid-19 and Nursing literature to discover underlying trends and developments at the global, national, institutional, and individual level using Scientometric indicators. The publications and citations data for the study were sourced from the Web of Science database published during 2020–2021. The most productive and leading countries are: USA with 621 (43.4%) share far by China with 136(9.5%), UK with 108 (7.5%) share and Australia with 101(7.1%) share and other countries are published less than 5% of publications. India possessed 14^th rank with 15 (1.0%) publications share. International collaboration …

A Pragmatic Machine Learning Model To Predict Carbapenem Resistance, Ryan J Mcguire, Sean C Yu, Philip R O Payne, Albert M Lai, M Cristina Vazquez-Guillamet, Marin H Kollef, Andrew P Michelson

Open Access Publications

Infection caused by carbapenem-resistant (CR) organisms is a rising problem in the United States. While the risk factors for antibiotic resistance are well known, there remains a large need for the early identification of antibiotic-resistant infections. Using machine learning (ML), we sought to develop a prediction model for carbapenem resistance. All patients >18 years of age admitted to a tertiary-care academic medical center between 1 January 2012 and 10 October 2017 with ≥1 bacterial culture were eligible for inclusion. All demographic, medication, vital sign, procedure, laboratory, and culture/sensitivity data were extracted from the electronic health record. Organisms were considered CR …

Effectiveness Of A Vaccination Education Module For College Freshman, Gavin Robert Behunin

Theses and Dissertations

The purpose of this thesis is to evaluate a vaccination education module and evaluate its effectiveness to improve vaccine beliefs and behaviors among college freshmen. The participants included 177 college freshmen at one Utah university. Participants were eligible for this study if admitted as a new freshman during the 2019-2020 school year. The study was a cross-sectional pre- and post-education evaluation assessing vaccine beliefs and behaviors using a Likert-type scale. After completing the vaccination education module, participants' vaccine beliefs and behavioral intentions improved. Participants reported they were more likely to be up-to-date on personal vaccines and more likely to expect …

Association Of Convalescent Plasma Therapy With Survival In Patients With Hematologic Cancers And Covid-19, Michael A. Thompson, Jeffrey P. Henderson, Pankil K. Shah, Samuel M. Rubinstein, Michael J. Joyner, Toni K. Choueiri, Daniel B. Flora, Elizabeth A. Griffiths, Anthony P. Gulati, Clara Hwang, Vadim S. Koshkin, Esperanza B. Papadopoulos, Elizabeth V. Robilotti, Christopher T. Su, Elizabeth M. Wulff-Burchfield, Zhuoer Xie, Peter Paul Yu, Sanjay Mishra, Jonathon W. Senefeld, Dimpy P. Shah, Jeremy L. Warner

Hematology/Oncology Articles

Importance: COVID-19 is a life-threatening illness for many patients. Prior studies have established hematologic cancers as a risk factor associated with particularly poor outcomes from COVID-19. To our knowledge, no studies have established a beneficial role for anti-COVID-19 interventions in this at-risk population. Convalescent plasma therapy may benefit immunocompromised individuals with COVID-19, including those with hematologic cancers.

Objective: To evaluate the association of convalescent plasma treatment with 30-day mortality in hospitalized adults with hematologic cancers and COVID-19 from a multi-institutional cohort.

Design, Setting, and Participants: This retrospective cohort study using data from the COVID-19 and Cancer Consortium registry with propensity …

Candida Cell‐Surface‐Specific Monoclonal Antibodies Protect Mice Against Candida Auris Invasive Infection, Jonothan Rosario‐Colon, Karen Eberle, Abby Adams, Evan Courville, Hong Xin

School of Graduate Studies Faculty Publications

Candida auris is a multidrug‐resistant fungal pathogen that can cause disseminated bloodstream infections with up to 60% mortality in susceptible populations. Of the three major classes of antifungal drugs, most C. auris isolates show high resistance to azoles and polyenes, with some clinical isolates showing resistance to all three drug classes. We reported in this study a novel approach to treating C. auris disseminated infections through passive transfer of monoclonal antibodies (mAbs) targeting cell surface antigens with high homology in medically important Candida spe-cies. Using an established A/J mouse model of disseminated infection that mimics human candidi-asis, we showed that …

The Impact Of Contact Tracing On The Spread Of Covid-19: An Egocentric Agent-Based Model, Andrew Pilny, Lin Xiang, Corey Huber, Will Silberman, Sean Goatley-Soan

Communication Faculty Publications

At its core, contact tracing is a form of egocentric network analysis (ENA). One of the biggest obstacles for ENA is informant accuracy (i.e., amount of true contacts identified), which is even more prominent for interaction-based network ties because they often represent episodic relational events, rather than enduring relational states. This research examines the effect of informant accuracy on the spread of COVID-19 through an egocentric, agent-based model. Overall when the average person transmits COVID-19 to 1.62 other people (i.e., the R₀), they must be, on average, 75% accurate with naming their contacts. In higher transmission contexts (i.e., …

New Perspectives On Antimicrobial Agents: Ceftolozane-Tazobactam, Bryan D Lizza, Kevin D Betthauser, David J Ritchie, Scott T Micek, Marin H Kollef

Open Access Publications

Ceftolozane-tazobactam (C/T) is a new fifth-generation cephalosporin/beta-lactamase inhibitor combination approved by the Food and Drug Administration and the European Medicines Agency for treatment of complicated intraabdominal infections, complicated urinary tract infections, and hospital-acquired pneumonia in adult patients. This review will briefly describe the pharmacology of C/T and focus on the emerging clinical trial and real-world data supporting its current utilization. Additionally, our synthesis of these data over time has set our current usage of C/T at Barnes-Jewish Hospital (BJH). C/T is primarily employed as directed monotherapy at BJH when Pseudomonas aeruginosa isolates are identified with resistance to other beta-lactams. C/T …

Evaluation Of Total Body Weight Versus Adjusted Body Weight Voriconazole Dosing In Obese Patients, Elizabeth Diller, Tamara Krekel, Andrej Spec, Jeff Klaus

Open Access Publications

This retrospective single-center study of a cohort of adult patients who received voriconazole with a steady-state trough concentration measured during therapy evaluated the rate of therapeutic trough attainment using adjusted body weight (AdjBW)-based and total body weight (TBW)-based dosing in overweight and obese patients. Of the 130 patients included, 45 patients received TBW-based dosing and 85 patients received AdjBW-based dosing. Therapeutic trough attainment was significantly improved with AdjBW-based dosing compared to TBW-based dosing (64.7% versus 46.7%;

Elite Cues And The Rapid Decline Of Trust In Science Agencies On Covid-19, Lawrence C. Hamilton, Thomas G. Safford

Faculty Publications

The COVID-19 pandemic has been marked by political divisions in US public trust of scientists. Such divisions are well known on other science topics, but regarding COVID-19 they arose suddenly, with disastrous results. Public distrust of scientists has been variously explained in terms of conflicts with belief systems, psychology, peer influences, or communication from elites. Three surveys conducted from March to July 2020 in the US state of New Hampshire observed changing perceptions on COVID-19, providing a test of alternative explanations. Over this period trust in science agencies such as the CDC for information on the coronavirus fell dramatically among …

Dietary Fiber Intake, The Gut Microbiome, And Chronic Systemic Inflammation In A Cohort Of Adult Men, Wenjie Ma, Yin Cao, Et Al.

2020-Current year OA Pubs

BACKGROUND: A higher intake of dietary fiber is associated with a decreased risk of chronic inflammatory diseases such as cardiovascular disease and inflammatory bowel disease. This may function in part due to abrogation of chronic systemic inflammation induced by factors such as dysbiotic gut communities. Data regarding the detailed influences of long-term and recent intake of differing dietary fiber sources on the human gut microbiome are lacking.

METHODS: In a cohort of 307 generally healthy men, we examined gut microbiomes, profiled by shotgun metagenomic and metatranscriptomic sequencing, and long-term and recent dietary fiber intake in relation to plasma levels of …

Covid-19: A One Health Issue, Karen Gruszynski

Cumberland Mountain Naturalist

COVID-19 has very rapidly become part of modern societal lexicon as the disease highlights the importance understanding zoonotic diseases and the impact they can have on human life. With a 177million human cases and 3.82million deaths globally at the time of this publication, the "One Health" nature of the disease has had a lasting impact across the planet. As the disease spread rapidly, it highlighted the dissemination of information through social media and other sources. With this in mind, Dr. Gary Vroegindewey, Director for One Health at LMU-CVM, put forth the idea to have students collect and summarize information about …

Data Sharing In Southeast Asia During The First Wave Of The Covid-19 Pandemic, Arianna Maever L. Amit, Veincent Christian F. Pepito, Bernardo Gutierrez, Thomas Rawson

Ateneo School of Medicine and Public Health Publications

Background: When a new pathogen emerges, consistent case reporting is critical for public health surveillance. Tracking cases geographically and over time is key for understanding the spread of an infectious disease and effectively designing interventions to contain and mitigate an epidemic. In this paper we describe the reporting systems on COVID-19 in Southeast Asia during the first wave in 2020, and highlight the impact of specific reporting methods.

Methods: We reviewed key epidemiological variables from various sources including a regionally comprehensive dataset, national trackers, dashboards, and case bulletins for 11 countries during the first wave of the epidemic in Southeast …

Covid-19 & Blm: Racial Inequity In Healthcare, Laken Berndt

University Honors Theses

In this review of scholarship on healthcare inequality, as well as recent scholarship focused on COVID-19, we find there are clear racial disparities within healthcare, seen within previous trends, as well as the current pandemic. Minorities have historically been at greater risk during prior health crises, as well as being at risk for various underlying health conditions, and now, there are higher rates of infection and mortality amongst minority groups.

Socioeconomic factors play an incredibly important role in these disparities, and much of the current discourse does regard socioeconomic status as a primary factor in these trends. However, we find …

Exploring Community Health Worker Roles, Support, And Experiences In The Context Of The Covid-19 Pandemic In Bangladesh, Frontline Health Project

Reproductive Health

This brief presents results from the Frontline Health project's study in Bangladesh which explores CHWs' perspectives and challenges providing support to their communities during COVID-19.

Solar Disinfection Of Turbid Hygiene Waters In Lexington, Ky, Usa, Atena Amirsoleimani, Gail M. Brion

Civil Engineering Faculty Publications

Solar disinfection (SODIS) could be a key to providing a clean, hygiene water for birthing uses, but the recommended climate zone is limited, the microbial indicators are related to gastrointestinal illness and not wound infections. SODIS feasibility was investigated to remove Escherichia coli from turbid water at temperatures less than 50 °C in Lexington, KY. Increasing turbidity from 0 to 200 NTU decreased E. coli inactivation from 5 to 1 log. With the same experimental protocol, more than 4-log inactivation of Staphylococcus aureus and Staphylococcus epidermidis (common human-skin microorganisms related to serious post-partum infections of both mother and child) was …

Evaluation Of Sex Education Curriculum And Policy Related To The Needs Of Lgbtq+ Latinx Youth, Olivia Nayler

University Honors Theses

Sex education is contentious and inconsistent in the United States but it is extremely necessary to address the health needs of young people and the adults they become. This study aims to evaluate how well comprehensive sex education curricula attend to the needs of high school age LGBTQ+ Latinx students. The curricula Our Whole Lives (OWL) and FLASH were chosen for the study as established sex education curricula based on their assertions of being factual and comprehensive, and for their adaptability in different settings and locations. A content analysis was performed on both curricula. In addition, an analysis of OAR …

Relationships Between Coping Mechanisms And Perceived Stress Of Portland State University Community Members Amidst Covid-19, Julie Goldman

University Honors Theses

Purpose: The purpose of this study was to assess the coping mechanisms used by the Portland State University (PSU) community and their relationships to perceived stress.

Methods: A virtual survey composed of demographic questions, the Perceived Stress Scale (PSS10), the Brief COPE, and two open-ended questions was distributed to the community. Data were collected from 231 respondents, mostly PSU students. Statistical Package for the Social Sciences (SPSS) was used to compute mean PSS score, adaptive coping score, and avoidant coping score. Pearson correlations and t-tests were run to explore the relationship between perceived stress and coping data.

Results: Perceived stress …

Plotting The Literature On Precautionary Measures Of Covid-19: A Scientometric Analysis Of Web Of Science, Muhammad Shoaib, Nusrat Ali, Abeel Naseer

Library Philosophy and Practice (e-journal)

This study attempted to evaluate the scholarly publications on COVID-19, social distance, physical distance, social isolation, and self-isolation employing the scientometric analysis technique from 2020 to 2021. The main purpose was to consolidate the published scholarship on the COVID-19 in the Web of Science indexed documents. A total of 635 publications were found. The results indicated that social distance and COVID-19 was the top topic along with the article as a type of document, and the majority were published in the English language in 2021. The name of Gimenez-Llort L was at top of the list of authors, along with …

Generation Of Antibiotic Resistant Mutants In The Minimal Pathogen Mycoplasma Pneumoniae, Bryant De Jesus

Theses and Dissertations

Mycoplasma pneumoniae (MPN) causes community acquired pneumonia (CAP). The inability to identify M. pneumoniae infections through common clinical screenings has added to the global antibiotic resistance problem. MPN characteristically lacks a cell wall, which prevents proper diagnosis in an infected patient. This has led to the inappropriate prescriptions of antibiotics at insufficient dosages, allowing these microorganisms to thrive at sub-lethal concentrations. The small genome size of MPN, makes it a viable candidate for studying and developing tools to understand the genetic mechanisms behind the acquisition of antibiotic resistance by microbes. This study aimed to generate MPN mutants through prolonged exposure …

Postojna-Planina Cave System In Slovenia, A Hotspot Of Subterranean Biodiversity And A Cradle Of Speleobiology, Maja Zagmajster, Slavko Polak, Cene Fišer

KIP Articles

The Postojna-Planina Cave System (PPCS) in central Slovenia is a globally exceptional site of subterranean biodiversity, comprised of many interconnected caves with cumulative passage length exceeding 34 km. Two rivers sink into the caves of the PPCS, called the Pivka and Rak, and join underground into Unica River, which emerges to the surface. The studies of fauna of PPCS began in the 19th century with the first scientific descriptions of specialized cave animals in the world, making it “the cradle of speleobiology”. Currently, the species list of PPCS contains 116 troglobiotic animal species belonging to eight phyla, confirming its status …

Unified In Pride: Lgbtq+ Patient Care And Research, Mary Ashley Canevaro

Browse All News

No abstract provided.

Assessment Of Pathogenic Changes In The Gut-Liver Axis In Plwh With Heavy Alcohol Drinking And Gut Dysbiosis Marked By Decreased Butyrogenic Potential., Smita Ghare, Vaughn Bryant, Richa Singhal, Sabina Gautam, Chanakya Charan Tirumala, Andrea Reyes-Vega, Craig J. Mcclain, Ronald Cohen, Varand Govind, Robert L. Cook, Shirish Barve

Faculty and Staff Scholarship

Purpose: People living with HIV infection (PLWH) experience increasing risk for non-AIDS diseases including liver dysfunction and injury. Both HIV-infection and heavy alcohol drinking (HAD) are known to cause gut microbial dysbiosis and systemic inflammation that may potentially contribute to altered Gut-Liver axis. However, the specific pathogenic features associated with combinatorial harmful effects of alcohol and HIV infection on gut-liver interactions are not completely understood. This study evaluate the pathogenic changes in the Gut-Liver axis in PLWH with HAD.

Microglial Implications In Sars-Cov-2 Infection And Covid-19: Lessons From Viral Rna Neurotropism And Possible Relevance To Parkinson's Disease, Ifeoluwa O. Awogbindin, Benneth Ben-Azu, Babatunde A. Olusola, Elizabeth T. Akinluyi, Philip A. Adeniyi, T. Di Paolo, Marie-Eve Tremblay

Faculty Publications

Since December 2019, humankind has been experiencing a ravaging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak, the second coronavirus pandemic in a decade after the Middle East respiratory syndrome coronavirus (MERS-CoV) disease in 2012. Infection with SARS-CoV-2 results in Coronavirus disease 2019 (COVID-19), which is responsible for over 3.1 million deaths worldwide. With the emergence of a second and a third wave of infection across the globe, and the rising record of multiple reinfections and relapses, SARS-CoV-2 infection shows no sign of abating. In addition, it is now evident that SARS-CoV-2 infection presents with neurological symptoms that include early …

A Monte Carlo Simulation Of A Protein (Cove) In A Matrix Of Random Barriers, R. B. Pandey

Faculty Publications

Monte Carlo simulations are performed to study structure and dynamics of a protein CoVE in random media generated by a random distribution of barriers at concentration c with a coarse-grained model in its native (low temperature) and denatured (high temperature) phase. The stochastic dynamics of the protein is diffusive in denature phase at low c, it slows down on increasing c and stops moving beyond a threshold (c_th ≈ 0.10). In native phase, the protein moves extremely slow at low c but speeds up on further increasing c in a characteristic range (c =0.10–0.20) before …