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2021

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Assessing The Role Of Cyberbiosecurity In Agriculture: A Case Study, Tiffany Drape, Noah Magerkorth, Anuradha Sen, Joseph J. Simpson, Megan Seibel, Randall Steven Murch, Susan E. Duncan Aug 2021

Assessing The Role Of Cyberbiosecurity In Agriculture: A Case Study, Tiffany Drape, Noah Magerkorth, Anuradha Sen, Joseph J. Simpson, Megan Seibel, Randall Steven Murch, Susan E. Duncan

International Business and Entrepreneurship Faculty Publications

Agriculture has adopted the use of smart technology to help meet growing food demands. This increased automation and associated connectivity increases the risk of farms being targeted by cyber-attacks. Increasing frequency of cybersecurity breaches in many industries illustrates the need for securing our food supply chain. The uniqueness of biological data, the complexity of integration across the food and agricultural system, and the importance of this system to the U.S. bioeconomy and public welfare suggests an urgency as well as unique challenges that are not common across all industries. To identify and address the gaps in awareness and knowledge as …


Triangle Journal News, Volume 1, Number 10 Aug 2021

Triangle Journal News, Volume 1, Number 10

Triangle Journal News, 1990-2006

Co-Editors: Allen Cook, John Stilwell. Staff Writers: Vincent Astor, Bob Dumais. Contributors: Becky Caperton, Lisa McGaughran, Gary Bodell. Typesetting and Layout: Allen Cook, John Stilwell, Bob Dumais, Vincent Astor. Advertising: Vincent Astor, Bob Dumais.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.


Using Alternative Teaching And Learning Approaches To Deliver Clinical Microbiology During The Covid19 Pandemic, Lovleen Tina Joshi Aug 2021

Using Alternative Teaching And Learning Approaches To Deliver Clinical Microbiology During The Covid19 Pandemic, Lovleen Tina Joshi

Peninsula Dental School

No abstract provided.


August 18, 2021 Greenmail, University Of Alabama At Birmingham Aug 2021

August 18, 2021 Greenmail, University Of Alabama At Birmingham

GreenMail (student newsletter through 2024)

No abstract provided.


Nurse Describes Conditions Inside A Covid-19 Unit, Laura Gasque Aug 2021

Nurse Describes Conditions Inside A Covid-19 Unit, Laura Gasque

Browse All News

No abstract provided.


Uab Study, Among Others, Shows Masks Are Effective In Preventing Spread Of Covid-19, Alicia Rohan Aug 2021

Uab Study, Among Others, Shows Masks Are Effective In Preventing Spread Of Covid-19, Alicia Rohan

Browse All News

No abstract provided.


The Size And Culturability Of Patient-Generated Sars-Cov-2 Aerosol, Joshua L. Santarpia, Vicki L. Herrera, Danielle N. Rivera, Shanna Ratnesar-Shumate, St. Patrick Reid, Daniel N. Ackerman, Paul Denton, Jacob W.S. Martens, Ying Fan, Nicholas Conoan, Michael V. Callahan, James V. Lawler, David M. Brett-Major, John J. Lowe Aug 2021

The Size And Culturability Of Patient-Generated Sars-Cov-2 Aerosol, Joshua L. Santarpia, Vicki L. Herrera, Danielle N. Rivera, Shanna Ratnesar-Shumate, St. Patrick Reid, Daniel N. Ackerman, Paul Denton, Jacob W.S. Martens, Ying Fan, Nicholas Conoan, Michael V. Callahan, James V. Lawler, David M. Brett-Major, John J. Lowe

Biology Faculty Publications

Background

Aerosol transmission of COVID-19 is the subject of ongoing policy debate. Characterizing aerosol produced by people with COVID-19 is critical to understanding the role of aerosols in transmission.

Objective

We investigated the presence of virus in size-fractioned aerosols from six COVID-19 patients admitted into mixed acuity wards in April of 2020.

Methods

Size-fractionated aerosol samples and aerosol size distributions were collected from COVID-19 positive patients. Aerosol samples were analyzed for viral RNA, positive samples were cultured in Vero E6 cells. Serial RT-PCR of cells indicated samples where viral replication was likely occurring. Viral presence was also investigated by western …


Family & Friends, Volume 8, Number 3 Aug 2021

Family & Friends, Volume 8, Number 3

Family & Friends, 1998-2006

Patricia Pair, Publisher. Anita C. Moyt, Managing Editor. Anthony Hardaway, Multi-Cultural Affairs Editor. Contributors: John Crossen, Jim Easter, Charlie Green, Hal Harmon, Katie Hiestand, Jim Norcross, Laer Gib Retae, Kevin Shaw, Rex Wockner.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.


Frailty Index In The Colonias On The Us-Mexico Border: A Special Report, Eron G. Manusov, Carolina Gomez De Ziegler, Vincent P. Diego, Gerardo Munoz-Monaco, Sarah Williams-Blangero Aug 2021

Frailty Index In The Colonias On The Us-Mexico Border: A Special Report, Eron G. Manusov, Carolina Gomez De Ziegler, Vincent P. Diego, Gerardo Munoz-Monaco, Sarah Williams-Blangero

School of Medicine Publications

Frailty is the age-related decline in well-being. The Frailty index (FI) measures the accumulation of health deficits and reflects biopsychosocial and cultural determinants of well-being. Frailty is measured as a static phenotype or as a Frailty Index comprising a ratio of suffered health deficits and total deficits. We report a Frailty Index calculated from routinely measured clinical variables gathered from residents of two Colonias (neighborhoods) in South Texas. A Colonia is a predominantly Hispanic, economically distressed, unincorporated neighborhood. We analyzed retrospective data from 894 patients that live in two Colonias located on the Texas-Mexico border. We calculated the FI with …


Exploring Relationship Between Perception Indicators And Mitigation Behaviors Of Soil Erosion In Undergraduate Students In Sonora, Mexico, Alondra María Díaz-Rodríguez, Claire Kelly, Valle A Del, Claudio Bravo-Linares, William Blake, Hugo Velasco, Dos Anjos R Meigikos, Laura Fernanda Barrera-Hernández, Los Santos-Villalobos S De Aug 2021

Exploring Relationship Between Perception Indicators And Mitigation Behaviors Of Soil Erosion In Undergraduate Students In Sonora, Mexico, Alondra María Díaz-Rodríguez, Claire Kelly, Valle A Del, Claudio Bravo-Linares, William Blake, Hugo Velasco, Dos Anjos R Meigikos, Laura Fernanda Barrera-Hernández, Los Santos-Villalobos S De

School of Geography, Earth and Environmental Sciences

Soil erosion represents a critical socio-economic and environmental hazard for Mexico and the world. Given that soil erosion is a phenomenon influenced by human activities, it is essential to know the level of cultural perspectives on this matter. An instrument with eight scales was applied to 275 university students from a northwestern Mexican city, which measured the knowledge about soil erosion, self-efficacy in solving the problem, future perspectives, perceived consequences, obstacles to addressing soil erosion, and mitigation intentions and behaviors. To analyze the relationship between the scales and the intentions and behaviors of soil erosion mitigation, a model of structural …


Exploring The Ecology Of Establishing Oak Trees In Urban Settings Of The Northeast, Tierney Bocsi, Rick W. Harper, Paige S. Warren, Stephen Destefano Aug 2021

Exploring The Ecology Of Establishing Oak Trees In Urban Settings Of The Northeast, Tierney Bocsi, Rick W. Harper, Paige S. Warren, Stephen Destefano

Cities and the Environment (CATE)

Urban forests notoriously lack diversity in the biological communities that inhabit them, from the age and species composition of street trees to wildlife populations. In reaction to invasions of nonnative insects and diseases as well as predicted response to climate change, an emerging number of community foresters and tree wardens are expanding their urban tree planting practices to include a broader assemblage of tree species. These include oaks, among other species able to tolerate and adapt to urban conditions. Oaks are potentially favorable in regions like the northeastern U.S., where they grow extensively in rural forests and demonstrate potential resistance …


2021-08-17_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services Aug 2021

2021-08-17_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated three times a week on Mondays, Wednesdays, and Fridays.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, …


Rheumatic Heart Disease In The United States: Forgotten But Not Gone: Results Of A 10 Year Multicenter Review., Sarah R De Loizaga, Lindsay Arthur, Bhawna Arya, Brian Beckman, Wubishet Belay, Cole Brokamp, Nak Hyun Choi, Sean Connolly, Soham Dasgupta, Tavenner Dibert, Marylou M Dryer, Lakshmi R Gokanapudy Hahn, Elizabeth Anne Greene, Daphney Kernizan, Omar Khalid, Jennifer Klein, Ryan Kobayashi, Subhrajit Lahiri, Raymond P Lorenzoni, Andrea Otero Luna, Jennifer Marshall, Theodore Millette, Lily Moore, Babu Muhamed, Meghna Murali, Kinjal Parikh, Amy Sanyahumbi, Divya Shakti, Elizabeth Stein, Sanket Shah, Hannah Wilkins, Mcallister Windom, Scott Wirth, Meghan Zimmerman, Andrew F Beck, Nicholas Ollberding, Craig Sable, Andrea Beaton Aug 2021

Rheumatic Heart Disease In The United States: Forgotten But Not Gone: Results Of A 10 Year Multicenter Review., Sarah R De Loizaga, Lindsay Arthur, Bhawna Arya, Brian Beckman, Wubishet Belay, Cole Brokamp, Nak Hyun Choi, Sean Connolly, Soham Dasgupta, Tavenner Dibert, Marylou M Dryer, Lakshmi R Gokanapudy Hahn, Elizabeth Anne Greene, Daphney Kernizan, Omar Khalid, Jennifer Klein, Ryan Kobayashi, Subhrajit Lahiri, Raymond P Lorenzoni, Andrea Otero Luna, Jennifer Marshall, Theodore Millette, Lily Moore, Babu Muhamed, Meghna Murali, Kinjal Parikh, Amy Sanyahumbi, Divya Shakti, Elizabeth Stein, Sanket Shah, Hannah Wilkins, Mcallister Windom, Scott Wirth, Meghan Zimmerman, Andrew F Beck, Nicholas Ollberding, Craig Sable, Andrea Beaton

Pediatrics Research and Scholarship

Background Recent evaluation of rheumatic heart disease (RHD) mortality demonstrates disproportionate disease burden within the United States. However, there are few contemporary data on US children living with acute rheumatic fever (ARF) and RHD. Methods and Results Twenty-two US pediatric institutions participated in a 10-year review (2008-2018) of electronic medical records and echocardiographic databases of children 4 to 17 years diagnosed with ARF/RHD to determine demographics, diagnosis, and management. Geocoding was used to determine a census tract-based socioeconomic deprivation index. Descriptive statistics of patient characteristics and regression analysis of RHD classification, disease severity, and initial antibiotic prescription according to community …


Cxcl1: A New Diagnostic Biomarker For Human Tuberculosis Discovered Using Diversity Outbred Mice., Deniz Koyuncu, Muhammad Khalid Khan Niazi, Thomas Tavolara, Claudia Abeijon, Melanie L Ginese, Yanghui Liao, Carolyn Mark, Aubrey Specht, Adam C Gower, Blanca I Restrepo, Daniel M Gatti, Igor Kramnik, Metin Gurcan, Bülent Yener, Gillian Beamer Aug 2021

Cxcl1: A New Diagnostic Biomarker For Human Tuberculosis Discovered Using Diversity Outbred Mice., Deniz Koyuncu, Muhammad Khalid Khan Niazi, Thomas Tavolara, Claudia Abeijon, Melanie L Ginese, Yanghui Liao, Carolyn Mark, Aubrey Specht, Adam C Gower, Blanca I Restrepo, Daniel M Gatti, Igor Kramnik, Metin Gurcan, Bülent Yener, Gillian Beamer

Faculty Research 2021

More humans have died of tuberculosis (TB) than any other infectious disease and millions still die each year. Experts advocate for blood-based, serum protein biomarkers to help diagnose TB, which afflicts millions of people in high-burden countries. However, the protein biomarker pipeline is small. Here, we used the Diversity Outbred (DO) mouse population to address this gap, identifying five protein biomarker candidates. One protein biomarker, serum CXCL1, met the World Health Organization's Targeted Product Profile for a triage test to diagnose active TB from latent M.tb infection (LTBI), non-TB lung disease, and normal sera in HIV-negative, adults from South Africa …


Contributors To Reduced Life Expectancy Among Native Americans In The Four Corners States, Olusola A. Omisakin, Hyojun Park, Max T. Roberts, Eric N. Reither Aug 2021

Contributors To Reduced Life Expectancy Among Native Americans In The Four Corners States, Olusola A. Omisakin, Hyojun Park, Max T. Roberts, Eric N. Reither

Sociology, Social Work and Anthropology Student Research

To assess trends in life expectancy and the contribution of specific causes of death to Native American-White longevity gaps in the Four Corners states, we used death records from the National Center for Health Statistics and population estimates from the U.S. Census Bureau from 1999–2017 to generate period life tables and decompose racial gaps in life expectancy. Native American-White life expectancy gaps narrowed between 2001 and 2012 but widened thereafter, reaching 4.92 years among males and 2.06 years among females in 2015. The life expectancy disadvantage among Native American males was primarily attributable to motor vehicle accidents (0.96 years), liver …


Family & Friends, Volume 6, Number 8 Aug 2021

Family & Friends, Volume 6, Number 8

Family & Friends, 1998-2006

Patricia Pair, Publisher. Anita C. Moyt, Managing Editor. Anthony Hardaway, Multi-Cultural Affairs Editor. Contributors: J. Shane Wilson, Laine McNeil, Rex Wockner, John Crossen, Kevin Shaw, Jim Easter, Katie Hiestand, Laer Gib Retae

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.


Evaluation Of Total Body Weight Versus Adjusted Body Weight Liposomal Amphotericin B Dosing In Obese Patients, Michelle H Ting, Andrej Spec, Scott T Micek, David J Ritchie, Tamara Krekel Aug 2021

Evaluation Of Total Body Weight Versus Adjusted Body Weight Liposomal Amphotericin B Dosing In Obese Patients, Michelle H Ting, Andrej Spec, Scott T Micek, David J Ritchie, Tamara Krekel

Open Access Publications

Liposomal amphotericin B (LAmB) is used for various fungal infections, but it is unclear which dosing weight to use in obese patients. The purpose of this study was to compare clinical outcomes of adjusted body weight (adjBW) versus total body weight (TBW) dosing of LAmB. This single-center, retrospective cohort study included patients who received LAmB for definitive therapy and whose TBW exceeded 120% of their ideal body weight (IBW). Analyses were conducted for 3 mg/kg for adjBW versus TBW and 5 mg/kg for adjBW versus TBW. A total of 238 patients were included. For the 68 patients who received LAmB …


Rheumatic Heart Disease In The United States: Forgotten But Not Gone: Results Of A 10 Year Multicenter Review, Sarah R De Loizaga, Lakshmi R Gokanapudy Hahn, Et Al Aug 2021

Rheumatic Heart Disease In The United States: Forgotten But Not Gone: Results Of A 10 Year Multicenter Review, Sarah R De Loizaga, Lakshmi R Gokanapudy Hahn, Et Al

Open Access Publications

Background Recent evaluation of rheumatic heart disease (RHD) mortality demonstrates disproportionate disease burden within the United States. However, there are few contemporary data on US children living with acute rheumatic fever (ARF) and RHD. Methods and Results Twenty-two US pediatric institutions participated in a 10-year review (2008-2018) of electronic medical records and echocardiographic databases of children 4 to 17 years diagnosed with ARF/RHD to determine demographics, diagnosis, and management. Geocoding was used to determine a census tract-based socioeconomic deprivation index. Descriptive statistics of patient characteristics and regression analysis of RHD classification, disease severity, and initial antibiotic prescription according to community …


The Histories Of Hivs : The Emergence Of The Multiple Viruses That Caused The Aids Epidemics, William H. Schneider Aug 2021

The Histories Of Hivs : The Emergence Of The Multiple Viruses That Caused The Aids Epidemics, William H. Schneider

Ohio University Press Open Access Books

This new collection of essays on HIV viruses spans disciplines to topple popular narratives about the origins of the AIDS pandemic and the impact of the disease on public health policy.

With a death toll in the tens of millions, the AIDS pandemic was one of the worst medical disasters of the past century. The disease was identified in 1981, at the height of miraculous postwar medical achievements, including effective antibiotics, breakthrough advances in heart surgery and transplantations, and cheap, safe vaccines—smallpox had been eradicated just a few years earlier. Arriving as they did during this era of confidence in …


Phylogenetic And Drug-Resistance Analysis Of Hiv-1 Sequences From An Extensive Paediatric Hiv-1 Outbreak In Larkana, Pakistan, Syed Hani Abidi, George Makau Nduva, Dilsha Siddiqui, Wardah Rafaqat, Syed Faisal Mahmood, Amna Rehana Siddiqui, Apsara Ali, Aneeta Hotwani, Rashida Abbas Ferrand, Fatima Mir Aug 2021

Phylogenetic And Drug-Resistance Analysis Of Hiv-1 Sequences From An Extensive Paediatric Hiv-1 Outbreak In Larkana, Pakistan, Syed Hani Abidi, George Makau Nduva, Dilsha Siddiqui, Wardah Rafaqat, Syed Faisal Mahmood, Amna Rehana Siddiqui, Apsara Ali, Aneeta Hotwani, Rashida Abbas Ferrand, Fatima Mir

Department of Biological & Biomedical Sciences

Introduction: In April 2019, an HIV-1 outbreak among children occurred in Larkana, Pakistan, affecting more than a thousand children. It was assumed that the outbreak originated from a single source, namely a doctor at a private health facility. In this study, we performed subtype distribution, phylogenetic and drug-resistance analysis of HIV-1 sequences from 2019 outbreak in Larkana, Pakistan.
Methods: A total of 401 blood samples were collected between April-June 2019, from children infected with HIV-1 aged 0-15 years recruited into a case-control study to investigate the risk factors for HIV-1 transmission. Partial HIV-1 pol sequences were generated from 344 blood …


Covid-19 Newsletter (Vol. 85), Center For Disaster Medicine, New York Medical College Aug 2021

Covid-19 Newsletter (Vol. 85), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.


Ability Of Video Telemetry To Predict Unplanned Hospital Admissions For Single Ventricle Infants., Doaa Aly, Lori Erickson, Hayley S. Hancock, Johnathan Apperson, Monica Gaddis, Girish S. Shirali, Suma Goudar Aug 2021

Ability Of Video Telemetry To Predict Unplanned Hospital Admissions For Single Ventricle Infants., Doaa Aly, Lori Erickson, Hayley S. Hancock, Johnathan Apperson, Monica Gaddis, Girish S. Shirali, Suma Goudar

Manuscripts, Articles, Book Chapters and Other Papers

Background: Our Cardiac High Acuity Monitoring Program (CHAMP) uses home video telemetry (HVT) as an adjunct to monitor infants with single ventricle during the interstage period. This study describes the development of an objective early warning score using HVT, for identification of infants with single ventricle at risk for clinical deterioration and unplanned hospital admissions (UHA).

Methods and Results: Six candidate scoring parameters were selected to develop a pragmatic score for routine evaluation of HVT during the interstage period. We evaluated the individual and combined ability of these parameters to predict UHA. All infants with single ventricle monitored at home …


Rheumatic Heart Disease In The United States: Forgotten But Not Gone: Results Of A 10 Year Multicenter Review., Sarah R. De Loizaga, Lindsay Arthur, Bhawna Arya, Brian Beckman, Wubishet Belay, Cole Brokamp, Nak Hyun Choi, Sean Connolly, Soham Dasgupta, Tavenner Dibert, Marylou M. Dryer, Lakshmi R. Gokanapudy Hahn, Elizabeth Anne Greene, Daphney Kernizan, Omar Khalid, Jennifer Klein, Ryan Kobayashi, Subhrajit Lahiri, Raymond P. Lorenzoni, Andrea Otero Luna, Jennifer A. Marshall, Theodore Millette, Lily Moore, Babu Muhamed, Meghna Murali, Kinjal Parikh, Amy Sanyahumbi, Divya Shakti, Elizabeth Stein, Sanket Shah, Hannah Wilkins, Mcallister Windom, Scott Wirth, Meghan Zimmerman, Andrew F. Beck, Nicholas Ollberding, Craig Sable, Andrea Beaton Aug 2021

Rheumatic Heart Disease In The United States: Forgotten But Not Gone: Results Of A 10 Year Multicenter Review., Sarah R. De Loizaga, Lindsay Arthur, Bhawna Arya, Brian Beckman, Wubishet Belay, Cole Brokamp, Nak Hyun Choi, Sean Connolly, Soham Dasgupta, Tavenner Dibert, Marylou M. Dryer, Lakshmi R. Gokanapudy Hahn, Elizabeth Anne Greene, Daphney Kernizan, Omar Khalid, Jennifer Klein, Ryan Kobayashi, Subhrajit Lahiri, Raymond P. Lorenzoni, Andrea Otero Luna, Jennifer A. Marshall, Theodore Millette, Lily Moore, Babu Muhamed, Meghna Murali, Kinjal Parikh, Amy Sanyahumbi, Divya Shakti, Elizabeth Stein, Sanket Shah, Hannah Wilkins, Mcallister Windom, Scott Wirth, Meghan Zimmerman, Andrew F. Beck, Nicholas Ollberding, Craig Sable, Andrea Beaton

Manuscripts, Articles, Book Chapters and Other Papers

Background Recent evaluation of rheumatic heart disease (RHD) mortality demonstrates disproportionate disease burden within the United States. However, there are few contemporary data on US children living with acute rheumatic fever (ARF) and RHD. Methods and Results Twenty-two US pediatric institutions participated in a 10-year review (2008-2018) of electronic medical records and echocardiographic databases of children 4 to 17 years diagnosed with ARF/RHD to determine demographics, diagnosis, and management. Geocoding was used to determine a census tract-based socioeconomic deprivation index. Descriptive statistics of patient characteristics and regression analysis of RHD classification, disease severity, and initial antibiotic prescription according to community …


Antibiotic Resistance In A Changing North: Unearthing The Effects Of Disturbance-Induced Permafrost Thaw On The Alaskan Soil Resistome, Tracie J. Haan Aug 2021

Antibiotic Resistance In A Changing North: Unearthing The Effects Of Disturbance-Induced Permafrost Thaw On The Alaskan Soil Resistome, Tracie J. Haan

Biological Sciences

The evolution of antibiotic resistance in pathogenic bacteria is a major threat at the forefront of public health today. By studying soils, one of the ancestral origins of antibiotic production and resistance, we can gain insight into how antibiotic resistance genes (ARGs) from the environment have contributed to the evolution and emergence of resistance in pathogens. These studies are particularly important in soils where polar amplification and human expansion has already impacted the frequency and intensity of soil disturbance events (e.g., wildfires, deglaciation, land-use). In Alaska these disturbances augment permafrost thaw shifting the biogeochemical properties of active layer soils that …


Using Ultraconserved Elements To Estimate Gene Flow Between Asian And North American Avian Taxa, Fern R. Spaulding Aug 2021

Using Ultraconserved Elements To Estimate Gene Flow Between Asian And North American Avian Taxa, Fern R. Spaulding

Biological Sciences

Alaska is a prime location to study avian speciation, divergence, and gene flow. The area of Beringia, the region extending from the Russian Far East across the Bering Sea though Alaska, has historically experienced periodic cycles of glaciation. These cyclic fluctuations in climate have had genetic consequences on the organisms that reside in this region. In this thesis, I examine the genetic relationships between Old World and New World lineages of Holarctic avian taxa. Specifically, I examine how intercontinental movements (i.e., gene flow) have shaped divergence, speciation, and phylogenetic relationships in several key lineages of Holarctic waterbirds. Using ultraconserved elements …


Electrochemical Micro-Aptasensors For Exosome Detection Based On Hybridization Chain Reaction Amplification, Wenfen Zhang, Zhenhua Tian, Shujie Yang, Joseph Rich, Shuaiguo Zhao, Mikael Klingeborn, Po-Hsun Huang, Zhishang Li, Alexander Stout, Quinn Murphy, Edward Patz, Shusheng Zhang, Guozhen Liu, Tony Jun Huang Aug 2021

Electrochemical Micro-Aptasensors For Exosome Detection Based On Hybridization Chain Reaction Amplification, Wenfen Zhang, Zhenhua Tian, Shujie Yang, Joseph Rich, Shuaiguo Zhao, Mikael Klingeborn, Po-Hsun Huang, Zhishang Li, Alexander Stout, Quinn Murphy, Edward Patz, Shusheng Zhang, Guozhen Liu, Tony Jun Huang

Faculty Publications

Exosomes are cell-derived nanovesicles that have recently gained popularity as potential biomarkers in liquid biopsies due to the large amounts of molecular cargo they carry, such as nucleic acids and proteins. However, most existing exosome-based analytical sensing methods struggle to achieve high sensitivity and high selectivity simultaneously. In this work, we present an electrochemical micro-aptasensor for the highly sensitive detection of exosomes by integrating a micropatterned electrochemical aptasensor and a hybridization chain reaction (HCR) signal amplification method. Specifically, exosomes are enriched on CD63 aptamer-functionalized electrodes and then recognized by HCR products with avidin-horseradish peroxidase (HRP) attached using EpCAM aptamers as …


Uab School Of Public Health Launches Free, Asymptomatic Covid-19 Testing Program For Alabama K-12 Schools, Hannah Echols Aug 2021

Uab School Of Public Health Launches Free, Asymptomatic Covid-19 Testing Program For Alabama K-12 Schools, Hannah Echols

Browse All News

No abstract provided.


Family & Friends, Volume 3, Number 8 Aug 2021

Family & Friends, Volume 3, Number 8

Family & Friends, 1998-2006

Anita C. Moyt, Managing Editor. Contributers: J. Shane Wilson, Dana Ferguson, Steven Bradford, Melida McSparrin, Laine McNeil, Rex Wockner, Gip Plaster, John Anderson, Lam Medallion.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.


Family & Friends, Volume 5, Number 1 Aug 2021

Family & Friends, Volume 5, Number 1

Family & Friends, 1998-2006

Anita C. Moyt, Managing Editor. Contributors: J. Shane Wilson, Laine McNeil, Rex Wockner, Lam Medallion, Alison Tate, Cole Walker, John Crossen.

Special thanks to Rhodes College and the Paul Barret Jr. Library for providing initial scanning of this collection.


Chagas Disease In Hiv-Infected Patients: It’S Time To Consider The Diagnosis, Melissa Nolan Ph.D., Mph, Natasha S. Hochberg Aug 2021

Chagas Disease In Hiv-Infected Patients: It’S Time To Consider The Diagnosis, Melissa Nolan Ph.D., Mph, Natasha S. Hochberg

Faculty Publications

No abstract provided.