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2021

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The Role Of Lateralisation And Sex On Insular Cortex: 3d Volumetric Analysis, Fatma Öz, Ni̇yazi̇ Acer, Ni̇han Katayifçi, Güneş Aytaç, Kami̇l Karaali̇, Muzaffer Si̇ndel Jan 2021

The Role Of Lateralisation And Sex On Insular Cortex: 3d Volumetric Analysis, Fatma Öz, Ni̇yazi̇ Acer, Ni̇han Katayifçi, Güneş Aytaç, Kami̇l Karaali̇, Muzaffer Si̇ndel

Turkish Journal of Medical Sciences

Background/aim: The insula has attracted the attention of many neuroimaging studies because of its key role between brain structures. However, the number of studies investigating the effect of sex and laterality on insular volume is insufficient. The aim of this study was to investigate the differences in insular volume between sexes and hemispheres. Materials and methods: A total of 47 healthy participants [24 males (20.08 ± 1.44 years) and 23 females (19.57 ± 0.90 years)] underwent magnetic resonance imaging (MRI). Imaging was performed using the 3T MRI scanner. The insular volume was measured using the Individual Brain Atlases using Statistical …

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Clinical Implications Of Fungal Isolation From Sputum In Adult Patients With Cystic Fibrosis, İli̇m Irmak, Ebru Damadoğlu, Damla Karadeni̇z Güven, Xursud Huseynova, Ahmet Çağkan İnkaya, Berri̇n Er, Ali̇ Korhan Siğ, Dolunay Gülmez Kivanç, Sevtap Arikan, Di̇lber Ademhan Tural, Deni̇z Doğru Ersöz, Hayri̇ye Uğur Özçeli̇k, Emi̇ne Nural Ki̇per, Ali̇ Fuat Kalyoncu Jan 2021

Clinical Implications Of Fungal Isolation From Sputum In Adult Patients With Cystic Fibrosis, İli̇m Irmak, Ebru Damadoğlu, Damla Karadeni̇z Güven, Xursud Huseynova, Ahmet Çağkan İnkaya, Berri̇n Er, Ali̇ Korhan Siğ, Dolunay Gülmez Kivanç, Sevtap Arikan, Di̇lber Ademhan Tural, Deni̇z Doğru Ersöz, Hayri̇ye Uğur Özçeli̇k, Emi̇ne Nural Ki̇per, Ali̇ Fuat Kalyoncu

Turkish Journal of Medical Sciences

Background/aim: Cystic fibrosis is an autosomal recessive disease with a defect in mucociliary activity that is characterized by recurrent pulmonary infections. Bacterial agents frequently implicated in airway colonization are Haemophilus influenzae, Staphylococcus spp., and Pseudomonas spp. Fungal isolation from sputum is common in adults. However, growth of fungal agent only in sputum culture in patients with cystic fibrosis is insufficient for the diagnosis of fungal diseases. There is limited data about the clinical significance of fungal isolation in sputum cultures. The aim of the study was to investigate the clinical outcomes andsignificance of fungal isolation from sputum samples in adult …

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Neonatal Pneumothorax From The Perspective Of A Pediatric Surgeon: Classification Andmanagement Protocol: A Preliminary Algorithm., Mirzaman Huseynov, Ali̇ Ekber Hakalmaz Jan 2021

Neonatal Pneumothorax From The Perspective Of A Pediatric Surgeon: Classification Andmanagement Protocol: A Preliminary Algorithm., Mirzaman Huseynov, Ali̇ Ekber Hakalmaz

Turkish Journal of Medical Sciences

Background/aim: Current neonatal pneumothorax classifications based on air volume escaping in pleural space have no contribution on the treatment. Therefore, our aim was to classify neonatal pneumothorax to guide treatment management based on our experiences. Material and methods: The records of all neonates admitted to our clinics from March 2017 to August 2020 were reviewed. The patients with pneumothorax were identified through the neonatology department patient database search. The study only included the patients with symptomatic pneumothorax and these patients were evaluated into 3 groups based on the changes in peripheral oxygen saturation (SpO2 ) and clinical features immediately after …

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Evaluation Of Ambulance Calls For Patients Over 65 Years Of Age In İzmir, Turkey: A Twoyear Retrospective Analysis, Ahu Pakdemi̇rli̇, Başak Bayram, Erkan Güvenç, Hülya Elli̇dokuz Jan 2021

Evaluation Of Ambulance Calls For Patients Over 65 Years Of Age In İzmir, Turkey: A Twoyear Retrospective Analysis, Ahu Pakdemi̇rli̇, Başak Bayram, Erkan Güvenç, Hülya Elli̇dokuz

Turkish Journal of Medical Sciences

Background/aim: Analysis of interventions for special patient groups is important for the planning of health services, especially emergency medical services. In this study, we aimed to evaluate emergency medical service (EMS) interventions for the elderly and determine the decisive factors affecting transfer to the hospital of EMS team over 2 years (2017 and 2018) in İzmir. Materials and methods: Records of 112 emergency calls that were made between 2017 and 2018 followed up with interventions for patients aged 65 years and older were obtained from the 112 system. The reasons for the calls, outcomes, possible diagnoses of the patients, differences …

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Cadaver Versus Simulator Based Arthroscopic Training In Shoulder Surgery, Gazi̇ Huri̇, Mert Ruşen Gülşen, Ece Belen Karmiş, Doğaç Karagüven Jan 2021

Cadaver Versus Simulator Based Arthroscopic Training In Shoulder Surgery, Gazi̇ Huri̇, Mert Ruşen Gülşen, Ece Belen Karmiş, Doğaç Karagüven

Turkish Journal of Medical Sciences

Introduction: There are few studies that compare the cadaver dissections with the medical simulators in means of talent improvement. Therefore, the aim of this study is to find out if using cadaver dissections is still the golden standard for surgical training or using the medical simulators in surgery could replace cadaver dissections. Materials and methods: The study is conducted during the European Orthopaedics & Traumatology Education Platform accredited Shoulder Club International Cadaver Course including a number of 34 orthopedics trainees. The participants were randomly divided into two groups to be trained with the simulator (Group 1) and on cadavers (Group …

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Evaluation Of The Learning Curve Of Pediatric Kidney Transplantation Anesthesia, Tümay Uludağ Yanaral, Peli̇n Karaaslan Jan 2021

Evaluation Of The Learning Curve Of Pediatric Kidney Transplantation Anesthesia, Tümay Uludağ Yanaral, Peli̇n Karaaslan

Turkish Journal of Medical Sciences

Background/aim: Pediatric kidney transplantation (PKT) anesthesia brings some different challenges than adult kidney transplantation (KT) anesthesia and there are still no studies analyzing the role of experience on PKT outcomes. In this study, we aimed to evaluate the anesthesia learning curve in pediatric kidney transplants performed in our institution and the effect of increasing experience on renal transplantation-related data. Materials and methods: Patients age ≤ 18 years who underwent KT were included in the study, while patients age >18 years were excluded. Patients were divided into 3 groups according to the date of transplant, as the first 10 patients in …

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Evaluation Of The Relationship Between Cranial Magnetic Resonance Imaging Findings Andclinical Status In Children With Cerebral Palsy, Ni̇han Şik, Fatma Ceren Sarioğlu, Özgür Özteki̇n, Berrak Sarioğlu Jan 2021

Evaluation Of The Relationship Between Cranial Magnetic Resonance Imaging Findings Andclinical Status In Children With Cerebral Palsy, Ni̇han Şik, Fatma Ceren Sarioğlu, Özgür Özteki̇n, Berrak Sarioğlu

Turkish Journal of Medical Sciences

Background/aim: The objective of this study was to evaluate the relationship between cranial magnetic resonance imaging (MRI) findings and clinical features in cerebral palsy (CP). Materials and methods: Children aged 3 to 18 years, who were followed with the diagnosis of CP between January 2012 and September 2015, were included. The type of CP was classified using the European Cerebral Palsy Monitoring Group's classification system and then, patients were divided into two groups as spastic or nonspastic groups. The Gross Motor Function Classification System (GMFCS) was used to determine the level of mobility. According to the GMFCS, levels 1, 2, …

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Impact Of Frailty And Ultrasonography-Based Sarcopenia On The Development Ofpostoperative Complications In Gastrointestinal Cancer Patients, Gözde Şengül Ayçi̇çek, Ti̇muçi̇n Erol, Peli̇n Ünsal, Olgun Deni̇z, Osman Abbasoğlu, Meltem Gülhan Hali̇l Jan 2021

Impact Of Frailty And Ultrasonography-Based Sarcopenia On The Development Ofpostoperative Complications In Gastrointestinal Cancer Patients, Gözde Şengül Ayçi̇çek, Ti̇muçi̇n Erol, Peli̇n Ünsal, Olgun Deni̇z, Osman Abbasoğlu, Meltem Gülhan Hali̇l

Turkish Journal of Medical Sciences

Background/aim: Gastrointestinal (GI) system cancers are frequent among older adults and it is still difficult to predict which are at increased risk for postoperative complications. Frailty and sarcopenia are increasing problems of older population and may be associated with adverse outcomes. In this study we aimed to examine the effect of sarcopenia and frailty on postoperative complications in older patients undergoing surgery for GI cancers. Materials and methods: Forty-nine patients admitted to general surgery clinic with the diagnosis of gastrointestinal system cancers were included in this cross-sectional study. Frailty status was assessed using the Edmonton Frail Scale (EFS). Sarcopenia was …

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Effect Of Nondipper Hypertension On Coronary Artery Disease Progression In Patients Withchronic Coronary Syndrome, Deni̇z Elçi̇k, Mustafa Duran, Şaban Keleşoğlu, Zeki̇ Çeti̇nkaya, Si̇bel Boyluğ, Ridvan Yurt, Ali̇ Doğan, Mehmet Tuğrul İnanç, Ni̇hat Kalay Jan 2021

Effect Of Nondipper Hypertension On Coronary Artery Disease Progression In Patients Withchronic Coronary Syndrome, Deni̇z Elçi̇k, Mustafa Duran, Şaban Keleşoğlu, Zeki̇ Çeti̇nkaya, Si̇bel Boyluğ, Ridvan Yurt, Ali̇ Doğan, Mehmet Tuğrul İnanç, Ni̇hat Kalay

Turkish Journal of Medical Sciences

Background/aim: It has been suggested that there is a significant progress in coronary artery disease (CAD) by many pathophysiological mechanisms. Nondipper hypertension (NDH) has been shown to have higher target organ damage and have a higher rate of cardiovascular mortality and morbidity. In this study, we investigated the effect of nondipper hypertension on the progression of coronary atherosclerosis. Materials and methods: A total of 186 patients who underwent coronary angiography twice between 6 months and 3 years were included in the study. Coronary angiography was repeated on the admission day due to angina or positive exercise test and the patients …

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Prognostic Value Of The C-Reactive Protein To Albumin Ratio In Patients Undergoingprimary Percutaneous Coronary Intervention For St-Segment Elevation Myocardialinfarction, Özgür Söğüt, Tarik Akdemi̇r, Mehmet Mustafa Can Jan 2021

Prognostic Value Of The C-Reactive Protein To Albumin Ratio In Patients Undergoingprimary Percutaneous Coronary Intervention For St-Segment Elevation Myocardialinfarction, Özgür Söğüt, Tarik Akdemi̇r, Mehmet Mustafa Can

Turkish Journal of Medical Sciences

Background/aim: This study investigated whether baseline serum level of C-reactive protein (CRP)/albumin ratio is associated with infarct localization, number of vascular lesions, and in-hospital mortality in patients undergoing primary percutaneous coronary intervention (PCI) for acute ST elevation myocardial infarction (STEMI). Methods: The study population consisted of 116 patients diagnosed with STEMI. The CRP/albumin ratio at first admission, cardiac troponin-I (cTnI), PCI results, and clinical outcomes were recorded. Results: The mean CRP/albumin ratio, cTnI level, and mean number of vascular lesions were significantly higher in non-survivors than in survivors (p = 0.006, p = 0.004, and p = 0.007, respectively). Multivariate …

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Turkish Validity And Reliability Study Of Type 2 Diabetes Stigma Assessment Scale, Bahar İnkaya, Ezgi̇ Karadağ Jan 2021

Turkish Validity And Reliability Study Of Type 2 Diabetes Stigma Assessment Scale, Bahar İnkaya, Ezgi̇ Karadağ

Turkish Journal of Medical Sciences

Background/aim: Stigma has a high incidence and adversely affects people with diabetes. In this context, patients face difficulties such as fear of losing their jobs, travel restrictions, isolation from social life, problems related to mental health, and feeling of wellness. The aim of this study was to investigate the validity and reliability of the stigma assessment scale in individuals with type 2 diabetes. Materials and methods: The study sample consisted of 153 diabetic individuals. The validity of language, content, and construct were examined to evaluate the validity of the type 2 diabetes stigma assessment scale. Cronbach's alpha was used to …

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The Association Between Mrna Expression Of Resistin, Tnf- Α, Il-6, Il-8, And Er-Α Inperipheral Blood Mononuclear Cells And Breast Cancer, Masome Zare-Moayedi, Fatame Ahmmadpour, Mojtaba Rashidi, Ahmad Ahmadzadeh, Amirahmad Salmasi, Ghorban Mohammadzadeh Jan 2021

The Association Between Mrna Expression Of Resistin, Tnf- Α, Il-6, Il-8, And Er-Α Inperipheral Blood Mononuclear Cells And Breast Cancer, Masome Zare-Moayedi, Fatame Ahmmadpour, Mojtaba Rashidi, Ahmad Ahmadzadeh, Amirahmad Salmasi, Ghorban Mohammadzadeh

Turkish Journal of Medical Sciences

Background/aim: Adipocytokines, adipose tissue-derived proteins, were demonstrated to be involved in the pathogenesis of breast cancer. We assessed the mRNA expression of resistin, tumor necrosis factor-alpha (TNF-α), interleukins 6 and 8 (IL-6, and IL-8), and estrogen receptor alpha (ER-α) in peripheral blood mononuclear cells (PBMCs) of women with and without breast cancer. Materials and methods: The PBMCs were isolated from the whole blood of 32 women with breast cancer and 18 women without breast cancer using density gradient centrifugation. The mRNA expression of the target genes was measured by reverse-transcription polymerase chain reaction (RT-PCR). Body mass index was calculated, additionally, …

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Comparison Of Local Infiltration Analgesia And Interscalene Block For Postoperative Painmanagement In Shoulder Arthroscopy: A Prospective Randomized Controlled Trial, Olgun Bi̇ngöl, Alper Deveci̇, Semi̇h Başkan, Güzelali̇ Özdemi̇r, Enver Kiliç, Emrah Arslantaş Jan 2021

Comparison Of Local Infiltration Analgesia And Interscalene Block For Postoperative Painmanagement In Shoulder Arthroscopy: A Prospective Randomized Controlled Trial, Olgun Bi̇ngöl, Alper Deveci̇, Semi̇h Başkan, Güzelali̇ Özdemi̇r, Enver Kiliç, Emrah Arslantaş

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to compare the effects of local infiltration analgesia and interscalene brachial plexus block techniques on postoperative pain control and shoulder functional scores in patients undergoing arthroscopic rotator cuff repair. Materials and methods: Sixty patients who underwent arthroscopic rotator cuff repair were prospectively included in the study. Patients were randomly divided into two groups. Group 1 was comprised of patients who had interscalene brachial plexus block, while group 2 was comprised of patients who had local infiltration analgesia. In group 1, interscalene block was applied with 20 mL 0.5% bupivacaine. In group 2, the …

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Circumcision With Plastic Alisclamp Technique In 4733 Boys: Our Experiences To Reducecomplications, Alev Süzen, Süleyman Cüneyt Karakuş, Nazi̇le Ertürk Jan 2021

Circumcision With Plastic Alisclamp Technique In 4733 Boys: Our Experiences To Reducecomplications, Alev Süzen, Süleyman Cüneyt Karakuş, Nazi̇le Ertürk

Turkish Journal of Medical Sciences

Background/aim: We aim to report the outcomes of circumcisions performed with Alisclamp and our experiences to reduce the complications. Material and methods: Complications among circumcised males with Alisclamp between 2015 and 2018 were retrospectively analyzed. Patients were divided into two groups: Group 1 (n = 1429); patients circumcised in 2015-2016 and Group 2 (n = 3304); patients circumcised in 2017-2018. The different technical approaches in Group 2 are as follows: 1) Prevention of bleeding: In Group 2, we didn't pull the ventral prepuce to reduce the risk of frenulum injury and the foreskin was excised approximately 1-2 mm above the …

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Retrospective Evaluation Of The Pediatric Multicystic Dysplastic Kidney Patients:Experience Of Two Centers From Southeastern Turkey, Mehtap Akbalik Kara, Aysel Taktak, Caner Alparslan Jan 2021

Retrospective Evaluation Of The Pediatric Multicystic Dysplastic Kidney Patients:Experience Of Two Centers From Southeastern Turkey, Mehtap Akbalik Kara, Aysel Taktak, Caner Alparslan

Turkish Journal of Medical Sciences

Background/aim: The objective of this study is to determine the clinical features of unilateral multicystic dysplastic kidney (MCDK) patients. Materials and methods: The demographic, clinical, laboratory, and radiologic features of MCDK patients at Diyarbakır Children's Hospital and Diyarbakır Gazi Yaşargil Training and Research Hospital between January 2008-June 2019 were retrospectively evaluated. Results: A total of 111 [59 (53.2%) male and 52(46.8%) female] patients with MCDK were followed for a mean period of 41.89 ± 32.03 months. MCDK was located on the left and right sides in 46 (41.4%) and 65 (58.6%) of the children, respectively (p > 0.05). A total of …

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Prone Versus Barts "Flank-Free" Modified Supine Percutaneous Nephrolithotomy: Amatch-Pair Analysis, Uygar Mi̇çooğullari, Davut Kamaci, Mehmet Yildizhan, Furkan Umut Kiliç, Taha Çeti̇n, Özer Ural Çakici, Murat Keske, Mehmet Yi̇ği̇t Yalçin, Arslan Ardiçoğlu Jan 2021

Prone Versus Barts "Flank-Free" Modified Supine Percutaneous Nephrolithotomy: Amatch-Pair Analysis, Uygar Mi̇çooğullari, Davut Kamaci, Mehmet Yildizhan, Furkan Umut Kiliç, Taha Çeti̇n, Özer Ural Çakici, Murat Keske, Mehmet Yi̇ği̇t Yalçin, Arslan Ardiçoğlu

Turkish Journal of Medical Sciences

Background/aim: In this study, we aimed to compare the results of prone and Barts "flank-free" modified supine percutaneous nephrolithotomy (PCNL) operations in our clinic. Materials and methods: The data from patients that underwent Barts "flank-free" modified supine PCNL (BS-PCNL) (n = 52) between June 2018 and July 2020 and prone PCNL (P-PCNL) (n = 286) between April 2014 and June 2018 were retrospectively evaluated. Of those 286 patients, 104 patients whose sex, age, body mass index, American Society of Anesthesiology score, stone localization, stone size, and hydronephrosis matched the BS-PCNL group in a 1:2 ratio were included in the study. …

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Comparison Of Frozen-Thawed Embryo Transfer Protocols In Patients With Previouscycle Cancellation Due To Uterine Peristalsis: A Pilot Study, İlknur Selvi̇, Mehmet Erdem, Erhan Demi̇rdağ, Müni̇re Funda Cevher Akdulum, Cengi̇z Karakaya, Ahmet Erdem Jan 2021

Comparison Of Frozen-Thawed Embryo Transfer Protocols In Patients With Previouscycle Cancellation Due To Uterine Peristalsis: A Pilot Study, İlknur Selvi̇, Mehmet Erdem, Erhan Demi̇rdağ, Müni̇re Funda Cevher Akdulum, Cengi̇z Karakaya, Ahmet Erdem

Turkish Journal of Medical Sciences

Background/aim: To investigate the optimal protocol for frozen-thawed embryo transfer (FET) cycles in patients who previously had a cycle cancellation due to uterine peristalsis (UP). Materials and methods: Thirty-four patients with previous embryo transfer (ET) cancellation due to UP during artificial cycle (AC) were included retrospectively. In the proceeding cycle, endometrium was prepared with AC (n: 23) in AC-FET group or with stimulated cycle that contains letrozole (L) (n: 11) in L-FET group. Intravenous bolus dose of 6.75 mg atosiban (Tractocile; Ferring Pharmaceuticals, Switzerland) injection was performed to all patients of AC-FET group due to UP ≥ 4/min on the …

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The Effect Of Weather Variables On The Severity, Duration, And Frequency Of Headacheattacks In The Cases Of Episodic Migraine And Episodic Tension-Type Headache, Nergi̇s Akgün, Esra Aciman Demi̇rel, Mustafa Açikgöz, Ulufer Çelebi̇, Fürüzan Köktürk, Hüseyi̇n Tuğrul Atasoy Jan 2021

The Effect Of Weather Variables On The Severity, Duration, And Frequency Of Headacheattacks In The Cases Of Episodic Migraine And Episodic Tension-Type Headache, Nergi̇s Akgün, Esra Aciman Demi̇rel, Mustafa Açikgöz, Ulufer Çelebi̇, Fürüzan Köktürk, Hüseyi̇n Tuğrul Atasoy

Turkish Journal of Medical Sciences

Background/aim: Although many headache patients report that the frequency and severity of attacks vary according to the season or weather in clinical practice, the relationship between the characteristics of the attacks and the weather is not very clear in episodic headaches. We aimed to compare the effects of weather variables (temperature, wind speed, wind direction, humidity, pressure, ultraviolet index, and sunshine duration) on episodic migraine (EM) and episodic tension-type headache (ETTH) attacks (incidence, duration, and severity). Materials and methods: Fifty patients with EM and fifty patients with ETTH diagnosed according to International Classification of Headache Disorders-II are included in the …

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An Investigation Of The Factors That Influence Functional Improvement In Strokerehabilitation, Onur Altuntaş, Serkan Taş, Alp Çeti̇n Jan 2021

An Investigation Of The Factors That Influence Functional Improvement In Strokerehabilitation, Onur Altuntaş, Serkan Taş, Alp Çeti̇n

Turkish Journal of Medical Sciences

Background/aim: The purpose of this study was to determine effect of age, sex, affected extremity, disability severity, treatment type, cerebrovascular accident (CVA) etiology, number of treatment sessions, and CVA duration on the functional improvement of the stroke patients who participated in a physical medicine and rehabilitation program. Materials and methods: The research sample consisted of 322 stroke patients. Clinical and demographic features including age, sex, affected extremity, disability severity, treatment type, CVA etiology, number of treatment sessions, and CVA duration were recorded. Functional status was evaluated retrospectively by using the functional independence measure (FIM) at admission and discharge. Results: It …

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The Assessment Of The Effect Of Different Intraabdominal Pressures Used For Laparoscopiccholecystectomy Surgery On Optic Nerve Sheath Diameter: A Prospective Observationalcohort Study, Tuna Ertürk, Bülent Bariş Güven, Yadi̇gar Yilmaz Camgöz, Fulya Yurtsever, Ayşin Ersoy Jan 2021

The Assessment Of The Effect Of Different Intraabdominal Pressures Used For Laparoscopiccholecystectomy Surgery On Optic Nerve Sheath Diameter: A Prospective Observationalcohort Study, Tuna Ertürk, Bülent Bariş Güven, Yadi̇gar Yilmaz Camgöz, Fulya Yurtsever, Ayşin Ersoy

Turkish Journal of Medical Sciences

Background/aim: During laparoscopic cholecystectomy operations, increases in intraabdominal, intrathoracic, and intracranial pressures (ICP) can be seen after pneumoperitoneum created for surgical imaging. Orbital ultrasonography (USG), which has been developed in recent years, is a method that can evaluate the ICP by measuring the optic nerve sheath diameter (ONSD) from the eyeball. In our study, we aimed to evaluate whether different intraabdominal pressure values created during laparoscopic cholecystectomy operations correlate with ICP by measuring ONSD. Materials and methods: The study included a total of 90 patients with American Society of Anesthesiologists (ASA) physical status classification I (ASA I) and II (ASA …

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Effect Of Vitamin D Supplementation On Lower Extremity Motor Function And Ambulationin Stroke Patients, Ayça Utkan Karasu, Gülçi̇n Kaymak Karataş Jan 2021

Effect Of Vitamin D Supplementation On Lower Extremity Motor Function And Ambulationin Stroke Patients, Ayça Utkan Karasu, Gülçi̇n Kaymak Karataş

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to investigate the effect of vitamin D supplementation on ambulation and mobility in hospitalized patients undergoing stroke rehabilitation. Materials and methods: This study was conducted retrospectively between September 2020 and October 2020 at Gazi University Faculty of Medicine Physical Medicine and Rehabilitation Department. Seventy-six patients who received inpatient stroke rehabilitation treatment between May 2018 and February 2020 were included in the study. The patients were divided into two groups as those who did and did not take vitamin D supplements. Lower extremity motor function and ambulation status were compared using Brunnstrom recovery stage …

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Can Pre-Procedural Mri Signal Intensity Ratio Predict The Success Of Uterine Arteryembolization In Treatment Of Myomas?, Çağlayan Çakir, Fati̇h Kilinç, Muhammed Aki̇f Deni̇z, Sema Karakaş Jan 2021

Can Pre-Procedural Mri Signal Intensity Ratio Predict The Success Of Uterine Arteryembolization In Treatment Of Myomas?, Çağlayan Çakir, Fati̇h Kilinç, Muhammed Aki̇f Deni̇z, Sema Karakaş

Turkish Journal of Medical Sciences

Background/aim: Magnetic resonance (MR) images, signal intensity ratios calculated using region of interests (ROI) in T2W images by proportioning the dominant myoma to iliac muscle can aid patient selection and, thus, in achieving better outcomes with the uterine artery embolization (UAE) procedure. The present study investigates the association between the success of UAE treatment with signal intensity (SI) ratio of the dominant myoma to the iliac muscle in MR imaging performed prior to the procedure. Materials and methods: This is a retrospective study and included 30 patients who admitted to our clinic between February 2017 and July 2019 due to …

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Evaluation Of S100a12 Protein Levels In Children With Familial Mediterranean Fever, Yelda Türkmenoğlu, Eli̇f Güney, Di̇ğdem Bezen, Ahmet İrdem, Bi̇ray Ertürk, Hasan Dursun Jan 2021

Evaluation Of S100a12 Protein Levels In Children With Familial Mediterranean Fever, Yelda Türkmenoğlu, Eli̇f Güney, Di̇ğdem Bezen, Ahmet İrdem, Bi̇ray Ertürk, Hasan Dursun

Turkish Journal of Medical Sciences

Background/aim: Familial Mediterranean fever (FMF), the most common autoinflammatory disease in children, is characterized by recurrent febrile episodes. FMF is known to progress with chronic inflammation, particularly during attack periods. This study aimed to investigate the relationship of S100A12, an inflammatory marker, with attacks and inflammatory events in FMF patients. Materials and methods: The study included 57 patients diagnosed with FMF, 43 in an attack-free period and 14 in an attack period, and 31 healthy children as the control group. Only white blood cell (WBC) count, C-reactive protein (CRP) level, erythrocyte sedimentation rate (ESR), and S100A12 level were analyzed in …

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Sequential Analysis Of Single-Center Experience Of Living Donor Kidney Transplants Withseveral Vascular Anastomosis Techniques, Berri̇n Papi̇la Kundaktepe, Ali̇ Vedat Durgun, Ertuğrul Göksoy, Sali̇h Pekmezci̇, Meti̇n Kapan, Kaya Saribeyoğlu, Mehmet Veli̇dedeoğlu, Mehmet Eli̇çevi̇k Jan 2021

Sequential Analysis Of Single-Center Experience Of Living Donor Kidney Transplants Withseveral Vascular Anastomosis Techniques, Berri̇n Papi̇la Kundaktepe, Ali̇ Vedat Durgun, Ertuğrul Göksoy, Sali̇h Pekmezci̇, Meti̇n Kapan, Kaya Saribeyoğlu, Mehmet Veli̇dedeoğlu, Mehmet Eli̇çevi̇k

Turkish Journal of Medical Sciences

Background and aim: Vascular variations of grafts are handled with various reconstruction techniques in renal transplantation. We aimed to analyze the effects of these reconstruction techniques and sites on patient/graft outcomes. Materials and methods: Renal transplantation cases at the Transplantation Unit of the General Surgery Department, İstanbul University Cerrahpaşa Medical Faculty between January 1st, 2000 and December 31st, 2012 were analyzed retrospectively. Postoperative duplex ultrasound results, urea-creatinine reduction rates, and complications were evaluated. Results: There were 228 living-donor transplantation cases evaluated. For single-renal-artery living-donor transplantations, there were 45 end-to-side external iliac artery, 15 end-to-side internal iliac artery, 152 end-to-end internal …

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Detection Of Helicobacter Pylori By Invasive Tests In Adult Dyspeptic Patientsand Antibacterial Resistance To Six Antibiotics, Including Rifampicin In Turkey. Isclarithromycin Resistance Rate Decreasing?, Mustafa Akar, Fuat Aydin, Tuba Kayman, Seçi̇l Abay, Emre Karakaya Jan 2021

Detection Of Helicobacter Pylori By Invasive Tests In Adult Dyspeptic Patientsand Antibacterial Resistance To Six Antibiotics, Including Rifampicin In Turkey. Isclarithromycin Resistance Rate Decreasing?, Mustafa Akar, Fuat Aydin, Tuba Kayman, Seçi̇l Abay, Emre Karakaya

Turkish Journal of Medical Sciences

Background/aim: The prevalence of Helicobacter pylori is reported to be roughly 80% in Turkey, and only very few culture-based studies are available on antibacterial resistance in adult dyspeptic patients. This study was carried out in adult dyspeptic patients with an aim to: (i) detect H. pylori by invasive tests (culture, polymerase chain reaction, and histopathology) and (ii) determine the current resistance rates of H. pylori isolates to six antibiotics, including rifampicin. Materials and methods: This study was conducted in 422 adult dyspeptic patients. The presence of H. pylori was demonstrated by culture, polymerase chain reaction, and the histopathology of gastric …

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Impact Of Fetal Brain Tissue Derived Mesenchymal Stem Cell And Fibrin Glue On Facial Nervecrash Injury, Ömer Bayir, Tuğba Karagöz, Ferda Alpaslan Pinarli, Güli̇stan Sanem Saribaş, Candan Özoğul, Kemal Keseroğlu, Güleser Saylam, Emel Çadalli Tatar, Sevi̇lay Karahan, Bülent Öcal, Mehmet Hakan Korkmaz Jan 2021

Impact Of Fetal Brain Tissue Derived Mesenchymal Stem Cell And Fibrin Glue On Facial Nervecrash Injury, Ömer Bayir, Tuğba Karagöz, Ferda Alpaslan Pinarli, Güli̇stan Sanem Saribaş, Candan Özoğul, Kemal Keseroğlu, Güleser Saylam, Emel Çadalli Tatar, Sevi̇lay Karahan, Bülent Öcal, Mehmet Hakan Korkmaz

Turkish Journal of Medical Sciences

Background/aim: To evaluate the clinical and histopathological effects of fetal brain tissue derived mesenchymal stem cells (FBTMSC) and fibrin glue (FG) on the facial nerve (FN) regeneration in rats with traumatic FN injury. Materials and methods: Twenty-eight Sprague Dawley rats were included in the study and divided into 4 groups. Traumatic FN injury (FP) was created by a surgical clamp compression to the main trunk of left FN in all groups. In the control group (group 1) no treatment was applied, in group 2 (FBTMSC group) 2 × 106 FBTMSC was injected, in group 3 (FG group) only FG was …

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The Effect Of Testosterone Replacement Therapy On Bladder Functions, Histology, Apoptosis,And Rho-Kinase Expression In Bladder Outlet Obstruction And Hypogonadism Rat Model, Bariş Saylam, Ozan Efesoy, Rabi̇a Bozdoğan Arpaci, Ruki̇ye Nalan Ti̇fti̇k, Mesut Tek, Kansu Büyükafşar, Murat Bozlu, Selahi̇tti̇n Çayan Jan 2021

The Effect Of Testosterone Replacement Therapy On Bladder Functions, Histology, Apoptosis,And Rho-Kinase Expression In Bladder Outlet Obstruction And Hypogonadism Rat Model, Bariş Saylam, Ozan Efesoy, Rabi̇a Bozdoğan Arpaci, Ruki̇ye Nalan Ti̇fti̇k, Mesut Tek, Kansu Büyükafşar, Murat Bozlu, Selahi̇tti̇n Çayan

Turkish Journal of Medical Sciences

Background/aim: The effect of testosterone replacement therapy was investigated on bladder functions, histology, apoptosis as well as Rho-kinase expression in the rat bladder outlet obstruction (BOO) and hypogonadism models. Materials and methods: 30 mature male rats divided into 4 groups: sham group (n = 8), BOO group (n = 8), BOO + orchiectomy group (n = 7), BOO + orchiectomy + testosterone (T) treatment group (n = 7). Cystometric findings, apoptosis index, Rho-kinase (ROCK-2) expression, and smooth muscle/collagen ratio were compared. Results: BOO did not change ROCK-2 expression level, compared to sham group (P > 0.05). However, when compared to BOO …

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Investigation Of The Effect Of Hyperthyroidism On Endoplasmic Reticulum Stress And Transient Receptor Potential Canonical 1 Channel In The Kidney, Nuri̇ye Ezgi̇ Bektur, Erhan Şahi̇n, Sedat Kaçar, Ridvan Bağci, Şeri̇fe Karakaya, Di̇lek Burukoğlu Dönmez, Varol Şahi̇ntürk Jan 2021

Investigation Of The Effect Of Hyperthyroidism On Endoplasmic Reticulum Stress And Transient Receptor Potential Canonical 1 Channel In The Kidney, Nuri̇ye Ezgi̇ Bektur, Erhan Şahi̇n, Sedat Kaçar, Ridvan Bağci, Şeri̇fe Karakaya, Di̇lek Burukoğlu Dönmez, Varol Şahi̇ntürk

Turkish Journal of Medical Sciences

Background/aim: Hyperthyroidism is associated with results in increased glomerular filtration rate as well as increased renin-angiotensin-aldosterone activation. The disturbance of Ca2+ homeostasis in the endoplasmic reticulum (ER) is associated with many diseases, including diabetic nephropathy and hyperthyroidism. Transient receptor potential canonical 1 (TRPC1) channel is the first cloned TRPC family protein. Although it is expressed in many places in the kidney, its function is uncertain. TRPC1 is involved in regulating Ca2+ homeostasis, and its upregulation increases ER Ca2+ level, activates the unfolded protein response, which leads to cellular damage in the kidney. This study investigated the role of TRPC1 in …

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Contribution Of Amniotic Membrane To The Healing Of Iatrogenic Vas Deferens Injury, Sabri̇ Demi̇r, Ahmet Ertürk, Mehmet Zengi̇n, Di̇nçer Yildiz, Si̇yami̇ Karahan, Emrah Şenel Jan 2021

Contribution Of Amniotic Membrane To The Healing Of Iatrogenic Vas Deferens Injury, Sabri̇ Demi̇r, Ahmet Ertürk, Mehmet Zengi̇n, Di̇nçer Yildiz, Si̇yami̇ Karahan, Emrah Şenel

Turkish Journal of Medical Sciences

Background/aim: Iatrogenic vas deferens injury is one of the most serious complications of operations in the inguinal region. Vasovasostomy is performed as treatment. However, stenosis is common after vasovasostomy. Oligospermia or azoospermia may develop and result in infertility. This study aimed to investigate the effect of amniotic membrane on healing in vas deferens injuries. Materials and methods: Four groups consisting of 10 rats each were formed. No procedure was performed in Group-I. In GroupII, the left vas deferens was transected and left to spontaneous healing. In Group-III, the left vas deferens was transected, and endto-end anastomosis was performed. In Group-IV, …

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Protective And Therapeutic Effect Of Hydrogen Sulfide On Hemorrhagic Cystitis And Testisdysfunction Induced With Cyclophosphamide, Fi̇kri̇ye Yasemi̇n Özati̇k, Orhan Özati̇k, Yasemi̇n Tekşen, Semra Yi̇ği̇taslan, Nezi̇ha Senem Ari Jan 2021

Protective And Therapeutic Effect Of Hydrogen Sulfide On Hemorrhagic Cystitis And Testisdysfunction Induced With Cyclophosphamide, Fi̇kri̇ye Yasemi̇n Özati̇k, Orhan Özati̇k, Yasemi̇n Tekşen, Semra Yi̇ği̇taslan, Nezi̇ha Senem Ari

Turkish Journal of Medical Sciences

Backround/aim: Cyclophosphamide (CP) is a drug used for treatment of many malignant diseases. However, it can cause serious side effects such as hemorrhagic cystitis and male infertility. Hydrogen sulfide (H2 S) is a gaseous mediator and is suggested to have antioxidant, antiinflammatory, and antiapoptotic effects. In this study, dose-dependent effects of H2 S donor sodium hydrosulfide (NaHS) on cyclophosphamide-induced hemorrhagic cystitis and testicular dysfunction were investigated in rats. Material and methods: Rats were divided into 5 groups (n = 8): control, CP, NaHS25 μmol/kg, NaHS50 μmol/kg, and NaHS100 μmol/ kg. After treatment for 7 days intraperitoneally (ip), a single ip …

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