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2021

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Family And Household Characteristics And Violent Disciplinary Practices Towards The Children In Myanmar: An Analysis Of 2015-2016 Myanmar Demographic And Health Survey, Nyan Linn Jan 2021

Family And Household Characteristics And Violent Disciplinary Practices Towards The Children In Myanmar: An Analysis Of 2015-2016 Myanmar Demographic And Health Survey, Nyan Linn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: Violence against children is one of the challenging public health problems. Violent disciplines not only affect negative health impacts but also are against children's right. However, those violent methods are still widespread across the countries, especially within the family. For prevention and control, it is required to clearly understand the country-specific information of violent child disciplines. In Myanmar, there are very few studies focusing on this area. This study was aimed to investigate the prevalence and factors associated with violent disciplines against children in Myanmar.Methodology: This study was a secondary data analysis of nationally representative 2015-2016 Myanmar Demographic and …


Neuroprotective Effect Of Passiflora Edulissims Against Amyloid Beta-Induced Neurotoxicity, Shuqin Cao Jan 2021

Neuroprotective Effect Of Passiflora Edulissims Against Amyloid Beta-Induced Neurotoxicity, Shuqin Cao

Chulalongkorn University Theses and Dissertations (Chula ETD)

Alzheimer’s disease (AD) is a common and devastating disease characterized by pathological aggregations of beta-amyloid (Aβ) plaques extracellularly, and Tau tangles intracellularly. While our understandings of the aetiologies of AD have greatly expanded over the decades, there is no drug available to stop disease progression. This study involves two parts. First, we demonstrate the potential of P. edulis pericarp (PP) extract in protecting against Aβ-mediated neurotoxicity in mammalian cells and Caenorhabditis elegans models of AD. We show PP protects against memory deficit, neuronal loss, and promotes longevity in the Aβ model of AD via stimulation of mitophagy, the selective cellular …


Development Of Asiatic Acid-Loaded Solid Lipid Nanoparticles For Nose To Brain Delivery: Ex Vivo And In Vivo Evaluation, Tissana Rojanaratha Jan 2021

Development Of Asiatic Acid-Loaded Solid Lipid Nanoparticles For Nose To Brain Delivery: Ex Vivo And In Vivo Evaluation, Tissana Rojanaratha

Chulalongkorn University Theses and Dissertations (Chula ETD)

Asiatic acid (AA) has neuroprotective properties potential for prevention and treatment of Alzheimer’s disease. Natural waxes with various ratios of tween 80 and span 80 or soybean lecithin were formulated to obtain AA-loaded solid lipid nanoparticles (AA-SLN) in order to improve direct nose to brain transport. Optimal AA-SLN had particle size below 200 nm with uniform size distribution as confirmed by transmission electron microscope (TEM) results and zeta potential of nearly -30 mV indicating low risk on particle aggregation. Formulation with rice bran wax, tween80 and soybean lecithin (AA-RwS100) showed the highest drug content and entrapment efficiency of >98%. Differential …


Melanogenesis-Stimulating Isoflavonoids From Dalbergia Parviflora, Ponsawan Netcharoensirisuk Jan 2021

Melanogenesis-Stimulating Isoflavonoids From Dalbergia Parviflora, Ponsawan Netcharoensirisuk

Chulalongkorn University Theses and Dissertations (Chula ETD)

Melanin, a cellular pigment, found in skin, hair and eyes is produced by melanocytes located at the basal layer of epidermis. Abnormal melanin production causes various pigmentation diseases. Low melanin content or dysfunction of melanogenesis not only decreases self-confidence and the quality of life but also enhances skin damage by external stimuli. Until now, there has been no reported remedy that possesses high efficacy and safety profile for hypopigmentation treatment in human. Development of novel darkening compounds from natural resources has recently become of an interest. In this study, the potent melanin-stimulating agents were screened from 45 compounds isolated from …


Study Of Self-Assembled Hyaluronic Acid Based Nanogel As Solubilization And Stabilization System For Asiatic Acid, Yu Yu Win Jan 2021

Study Of Self-Assembled Hyaluronic Acid Based Nanogel As Solubilization And Stabilization System For Asiatic Acid, Yu Yu Win

Chulalongkorn University Theses and Dissertations (Chula ETD)

Asiatic acid (AA), natural triterpene found in Centalla asiatica, possesses polypharmacological properties that can contribute to the treatment and prophylaxis of various diseases. However, its hydrophobic nature and rapid metabolic rate lead to poor bioavailability. The aim of this research is to study nanogel system from hyaluronic acid (HA) for solubilization and stability enhancement of AA. Poly(N-isopropylacrylamide) (pNIPAM) was conjugated onto HA using carbodiimide reaction followed by 1H NMR characterization. pNIPAM-grafted HA (HA-pNIPAM) nanogels were prepared with three concentrations of polymer, 0.1%, 0.15% and 0.25% w/v in water by sonication method. AA was loaded into the nanogel by incubation method. …


Supplementing Pochonia Chlamydosporia With Botanicals For Management Of Meloidogyne Incognita Infesting Chickpea, Amir Khan, Manar Fawzi Bani Mfarrej, Moh Tariq, Mohd Asif, Hera Nadeem, Mansoor Ahmad Siddiqui, Mohamed Hashem, Saad Alamri, Faheem Ahmad Jan 2021

Supplementing Pochonia Chlamydosporia With Botanicals For Management Of Meloidogyne Incognita Infesting Chickpea, Amir Khan, Manar Fawzi Bani Mfarrej, Moh Tariq, Mohd Asif, Hera Nadeem, Mansoor Ahmad Siddiqui, Mohamed Hashem, Saad Alamri, Faheem Ahmad

All Works

Root-knot nematodes pose a severe threat to worldwide agricultural development. Due to the high toxicity of chemical nematicides, eco-friendly control strategies against root-knot nematodes need to be established. A pot and in vitro experiment were performed to estimate nematicidal potential of Pochonia chlamydosporia. P. chlamydosporia was used alone or in combination with two botanicals for controlling Meloidogyne incognita in chickpea. The laboratory assessment was performed with four prepared concentrations (S, S/2, S/10, S/25) of fungal inoculum of P. chlamydosporia against egg hatching and second-stage juvenile's mortality of M. incognita. All four concentrations reduced egg hatching and increased mortality of J2s. …


Cancer Incidence, Mortality, Years Of Life Lost, Years Lived With Disability, And Disability-Adjusted Life Years For 29 Cancer Groups From 2010 To 2019: A Systematic Analysis For The Global Burden Of Disease Study 2019, Jonathan M. Kocarnik, Global Burden Of Disease 2019 Cancer Collaboration, Ali Artaman Jan 2021

Cancer Incidence, Mortality, Years Of Life Lost, Years Lived With Disability, And Disability-Adjusted Life Years For 29 Cancer Groups From 2010 To 2019: A Systematic Analysis For The Global Burden Of Disease Study 2019, Jonathan M. Kocarnik, Global Burden Of Disease 2019 Cancer Collaboration, Ali Artaman

All Works

Importance: The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden. Objective: To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic Index (SDI) quintiles from 2010 to 2019. Evidence Review: The GBD 2019 estimation methods were used to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life years (DALYs) in 2019 and over the past decade. Estimates are also provided by quintiles of the SDI, a composite …


Real Life Jrpg, Jacob Wilson Jan 2021

Real Life Jrpg, Jacob Wilson

Electrical and Computer Engineering

JRPG is a very popular video game genre, it’s turn based battle system allows the player to create interesting strategies impossible to find in real time games.

The goal of Real Life JRPG is to bring that experience away from the TV. Fight a dragon by actually swinging a sword.

Up to 3 players will work together to defeat the dragon, attacking it will Lower it’s health points and if the Dragons health points reach 0 the players win. But the Dragon will retaliate and if all players lose their health points, the dragon win.


Covid-19 And Corporate Social Responsibility: Business Responses To The Pandemic In The Inland Northwest, Jacob H. Rooksby Jan 2021

Covid-19 And Corporate Social Responsibility: Business Responses To The Pandemic In The Inland Northwest, Jacob H. Rooksby

Law Faculty Publications

The novel coronavirus upended the world beginning in early spring of 2020. As travel ground to a halt, and governments issued stay-at-home orders, the impact on commerce was immediate and has proven to be lasting. Employees accustomed to working in offices and job sites were told to stay home. Certain industries received permission to have so-called “essential” personnel continue their labor in person, but for many employers the reality they faced was not so simple: learn to adapt to the new environment or succumb to the new environment. ...


Coming To Terms: Using Contract Theory To Understand The Detroit Water Shutoffs, Marissa Jackson Sow Jan 2021

Coming To Terms: Using Contract Theory To Understand The Detroit Water Shutoffs, Marissa Jackson Sow

Law Faculty Publications

After the City of Detroit underwent financial takeover and filed the largest municipal bankruptcy in American history in 2013, the city’s emergency manager encouraged mass water shutoffs as a way of making the city’s water utility a more attractive asset for sale—and for privatization—by ridding the water department of its association with bad debt. The sale never took place, but the water shutoff, too, became the largest ever in American history, with over 141,000 homes subjected to water disconnections over a period of over six years. The governor of the State of Michigan ordered that the shutoffs be temporarily suspended …


Catalog 2021-2022, University Of North Florida Jan 2021

Catalog 2021-2022, University Of North Florida

UNF Course Catalogs

No abstract provided.


Adolescent Obesity Case Study, Rachel Salvitti Jan 2021

Adolescent Obesity Case Study, Rachel Salvitti

All Student-Created Educational Resources

This handout shows some easy to digest information regarding adolescent obesity. It is targeted towards girls and suggests what they should or should not include in their daily habits to reduce their risk or continued development of obesity. The information presented is based off of MyPlate recommendations, as well as other studies of dietary interventions to improve health of adolescents suffering from or at risk of obesity.


Flight And Dietary Antioxidants Influence Antioxidant Expression And Activity In A Migratory Bird, Kristen J. Demoranville, Wales A. Carter, Barbara J. Pierce, Scott R. Mcwilliams Jan 2021

Flight And Dietary Antioxidants Influence Antioxidant Expression And Activity In A Migratory Bird, Kristen J. Demoranville, Wales A. Carter, Barbara J. Pierce, Scott R. Mcwilliams

Biology Faculty Publications

Ecologically-relevant factors such as exercise and diet quality can directly influence how physiological systems work including those involved in maintaining oxidative balance; however, to our knowledge, no studies to date have focused on how such factors directly affect expression of key components of the endogenous antioxidant system (i.e., transcription factors, select antioxidant genes, and corresponding antioxidant enzymes) in several metabolically active tissues of a migratory songbird. We conducted a 3-factor experiment that tested the following hypotheses: (H1) Daily flying over several weeks increases the expression of transcription factors NRF2 and PPARs as well as endogenous antioxidant genes (i.e., CAT, SOD1, …


Law's Ability To Further The "Menstrual Movement", Christopher A. Cotropia Jan 2021

Law's Ability To Further The "Menstrual Movement", Christopher A. Cotropia

Law Faculty Publications

"The current menstrual movement calls for overcoming the cultural stigma associated with menstruation, achieving “menstrual equity,” and ending “period poverty.” The stigma the movement seeks to address is that menstruation is seen as taboo, unclean, and impure. The movement’s aims are twofold: First, it wants to increase awareness of menstruation and remove discrimination against those who menstruate, thus achieving menstrual equity. Second, it intends to provide greater access to menstrual hygiene products (“MHPs”), particularly for homeless and lower income people, thus eliminating period poverty. To achieve these goals, the movement is advocating to legislatively eliminate the “tampon tax” and increase …


The Effects Of Singing Vs. Speech On Joint Engagement In A Young Child With Phelan-Mcdermid Syndrome, Marllys Banks, Hannah Kinney, Bridget Valla, Maura Jones Moyle Jan 2021

The Effects Of Singing Vs. Speech On Joint Engagement In A Young Child With Phelan-Mcdermid Syndrome, Marllys Banks, Hannah Kinney, Bridget Valla, Maura Jones Moyle

Speech Pathology and Audiology Faculty Research and Publications

Phelan-McDermid syndrome (PMS) is a rare genetic disorder typically caused by loss or disruption of the distal long arm of chromosome 22. Children with PMS exhibit severe to profound communication deficits, and the majority meet the criteria for Autism Spectrum Disorder (ASD). To date, no language or communication intervention studies focused on children with PMS exist in the literature despite a steady increase in diagnosed cases. Anecdotally, it has been reported that music facilitates learning and engagement in children with PMS. The purpose of this clinical case study is to investigate the effects of singing vs. speaking on joint engagement, …


Health Risk Assessment Of Burmese Related To Consumption Of Heavy Metals Contaminated Fish From Local Market In Bangkok, Thailand, Myat Myitzu Jan 2021

Health Risk Assessment Of Burmese Related To Consumption Of Heavy Metals Contaminated Fish From Local Market In Bangkok, Thailand, Myat Myitzu

Chulalongkorn University Theses and Dissertations (Chula ETD)

Heavy metals contamination in human through the ingestion of contaminated fish may lead to serious health problems. This study was a cross sectional study conducted during February and March 2022 in Bangkok, Thailand. The objectives of this study were 1) to find the concentration of heavy metals contaminated in fish from local market in Thailand 2) to find the cancer risk and non-cancer risk of heavy metals from fish consumption. Face-to-face interview and online questionnaire were used to collect the personal information of 400 Burmese living in Bangkok. As, Cd, Cr, Pb, and Hg were analyzed by ICP-MS from four …


Optimization Of Ethanol-Based Reactive Extraction Process For Spent Coffee Grounds Biodiesel Production Using Duo-Function Diazabicycloundecene As Catalyst And Solvent, Huan Luong Trien Jan 2021

Optimization Of Ethanol-Based Reactive Extraction Process For Spent Coffee Grounds Biodiesel Production Using Duo-Function Diazabicycloundecene As Catalyst And Solvent, Huan Luong Trien

Chulalongkorn University Theses and Dissertations (Chula ETD)

The intention of this master's thesis was conducted to evaluate the potential of using 1,8-Diazabicyclo [5.4.0] undec-7-ene (DBU) as an eco-friendly solvent and catalyst in the in-situ transesterification (in-situ TE) process for producing fatty acid ethyl ester (FAEE) from spent coffee grounds (SCGs) waste. Several parameters were also optimized the FAEE yield in this process by response surface methodology, including temperature, time, ethanol and DBU loading and water content in ethanol. Results showed that promising FAEE yield could achieved under 40 °C. Moreover, FAEE yield tended to decrease under high temperatures due to DBU and ethanol evaporation at 70 °C. …


Physical Property And Biological Activity Of Bioscaffold Containing The Extracted Native Collagen And Acemannan On Proliferation And Growth Factor Secretion In Primary Human Pulpal Cells, Aye Aye Thant Jan 2021

Physical Property And Biological Activity Of Bioscaffold Containing The Extracted Native Collagen And Acemannan On Proliferation And Growth Factor Secretion In Primary Human Pulpal Cells, Aye Aye Thant

Chulalongkorn University Theses and Dissertations (Chula ETD)

Dental pulp tissue regeneration is based on tissue engineering concepts using stem cells, scaffolds, and growth factors to regenerate the pulp-dentine complex. Up to now, native collagen is commonly used as a biomaterial scaffold for tissue regeneration due to its biocompatibility, biodegradability, and properties that mimic the natural extracellular matrix (ECM). However, the bioactivity of collagen scaffold on cell growth and differentiation, and regenerative activities such as extracellular matrix formation and growth factor secretion which are important for pulp revascularization and regeneration and accomplishment root formation is still unclear. Many studies elucidated that adding biomolecules into the collagen scaffold enhanced …


Parking Problems And Policies In Bangkok: Issues, Causes, And Implications, Chakaphan Chullabodhi Jan 2021

Parking Problems And Policies In Bangkok: Issues, Causes, And Implications, Chakaphan Chullabodhi

Chulalongkorn University Theses and Dissertations (Chula ETD)

Parking policies are integral to promoting sustainable urban mobility and enhancing a city's livability as they can shift people's movement toward more sustainable modes. However, Bangkok still lacks a concrete parking policy. The existing one consists primarily of regulations and standards that help reduce traffic congestion, albeit without well-defined policy objectives. This study examines the current problems of on-street and off-street parking policies, investigates the root causes of parking issues, and establishes a parking policy that supports the city's development of sustainable mobility. We used a modified conceptual framework comprising the Iceberg Model of analysis and the Political Economics Analysis …


An Sdn-Coordinated Multipath Transmission Steering Framework, Kiattikun Kawila Jan 2021

An Sdn-Coordinated Multipath Transmission Steering Framework, Kiattikun Kawila

Chulalongkorn University Theses and Dissertations (Chula ETD)

Data transfer is a primary mechanism that can directly affect the overall performance of Big Data analytic systems. This is because most data are generated from several locations. It has been challenging to collect and transfer data among multiple storage regions. Using the traditional single-path transfer approaches is not efficient to serve several requirements of Big Data applications. In this dissertation, we propose an SDN-coordinated multipath transmission steering framework for Big Data transfer application. Multipath TCP protocol (MPTCP) and SDN architecture are mainly considered to design and develop our multipath transmission framework. To provide a practical routing solution, we propose …


The Cross-Sectional Return Dispersion With Momentum Strategyand The Spill Over Across Fx And Equity Markets, During Covid-19, Pisit Grittiyarangsan Jan 2021

The Cross-Sectional Return Dispersion With Momentum Strategyand The Spill Over Across Fx And Equity Markets, During Covid-19, Pisit Grittiyarangsan

Chulalongkorn University Theses and Dissertations (Chula ETD)

This paper investigates the relation of momentum strategy and the return dispersion across currency and global equity markets by using 30 currency pairs and 30 global equity indices during last 2 decades. This paper also examines the lead-lag relationship of return dispersions through spillover from one market to another. In addition, we are successfully detected the relation between return dispersion of those market and the significant return by momentum strategy on currency market. However, we cannot detect significant positive return by using momentum strategy on global equity indices, so we cannot use the return dispersion from the lead market as …


The Stress And Burnout Among Lecturers In The Universities With Online Teaching In Vietnam During Covid-19 Pandemic: A Cross-Sectional Study, Anh Hoang Thi Ngoc Jan 2021

The Stress And Burnout Among Lecturers In The Universities With Online Teaching In Vietnam During Covid-19 Pandemic: A Cross-Sectional Study, Anh Hoang Thi Ngoc

Chulalongkorn University Theses and Dissertations (Chula ETD)

During COVID-19 pandemic, the education system is one of many aspects in our life which is changed according to the effect of pandemic. Changing from traditional teaching method to new digital teaching method, may lead to adverse health effects directly to mental health of lecturers, including stress and burnout. This study aimed 1) to investigate the level of stress and burnout among lecturers in the universities in Vietnam during COVID-19 pandemic 2) to find the association among demographic, COVID-19 factors, difficulties in teaching online, and stress, burnout among tertiary education lecturers in Vietnam. This study was a cross-sectional study conducted …


Health Risk Assessment Related To Cadmium And Lead Exposure From Cigarette Smoking Among Indonesian Smokers In Surakarta, Indonesia: A Cross-Sectional Study, Panji Mukti Jan 2021

Health Risk Assessment Related To Cadmium And Lead Exposure From Cigarette Smoking Among Indonesian Smokers In Surakarta, Indonesia: A Cross-Sectional Study, Panji Mukti

Chulalongkorn University Theses and Dissertations (Chula ETD)

Indonesia is one of the developing countries that have the highest number of smokers and ranks third under China and India. Heavy metal such as cadmium and lead poses major health hazards which are found in tobacco smoke. This study aimed 1) to assess the cancer risk and non-cancer risk related to lead and cadmium exposure from cigarette smoking among Indonesian smokers 2) to find the association between socio-demographic, exposure factors, and health risk among Indonesian smokers. This study was a cross-sectional study using an online questionnaire to get the personal information and smoking behavior among Indonesian male smokers who …


Effect Of Diamond Application On Dietary Intake And Bmi Among Over Nutrition Female College Student In Malang City, Indonesia: A Quasi-Experiment Study, Nurnaningsih Herya Ulfah Jan 2021

Effect Of Diamond Application On Dietary Intake And Bmi Among Over Nutrition Female College Student In Malang City, Indonesia: A Quasi-Experiment Study, Nurnaningsih Herya Ulfah

Chulalongkorn University Theses and Dissertations (Chula ETD)

Recently, using mobile applications for assisting weight loss programs is a common trend. However, the overnutrition rate is increasing every year. This research aims to develop and investigate the effect of Diet Monitoring (Diamond) application on dietary intake and BMI among overnutrition female college students in Malang City, Indonesia. Using 2 phases, this study used a cross-sectional study for phase I developing the app and a quasi-experiment for phase II investigating the effect of the application. 217 respondents were involved in phase I and 123 participants in phase II. The measurement tools were Tanita DC-360, and ZT-120 Health Scale, including …


Effectiveness Of Communication Program On Reduction Of Tb Stigma And Discrimination Among High-School Students In Bangkok: A Quasi-Experimental Study, Saowaluk Moonsarn Jan 2021

Effectiveness Of Communication Program On Reduction Of Tb Stigma And Discrimination Among High-School Students In Bangkok: A Quasi-Experimental Study, Saowaluk Moonsarn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Tuberculosis (TB) is a contagious disease through airborne transmission, and it is still a major cause of illness in Thailand. In addition, some patients with TB infection suffer from stigma and discrimination while living in their community. However, the stigma of TB patients is also reported to be high among high school students. The study aimed to explore the effectiveness of communication program on reduction of TB stigma and discrimination among high-school students in Bangkok. A quasi-experimental study was implemented in two high schools with 212 high-school students (Experimental group =108; Control group=104). Purposive and systematic sampling techniques were adopted …


Association Between Working Condition And Musculoskeletal Disorders (Msds) Among Female Garmentworkers In Khan Mean Chey, Phnom Penh City, Cambodia, Try Phally Jan 2021

Association Between Working Condition And Musculoskeletal Disorders (Msds) Among Female Garmentworkers In Khan Mean Chey, Phnom Penh City, Cambodia, Try Phally

Chulalongkorn University Theses and Dissertations (Chula ETD)

Musculoskeletal disorders (MSDs) are a serious public health issue in both industrialized and developing countries. This study aims to investigate the prevalence of musculoskeletal symptoms and the association between working conditions and MSDs among female garment workers in Khan Mean Chey, Phnom Penh city, Cambodia. A cross-sectional research design was conducted among 423 female garment workers. Data collection was convenient sampling through face-to-face interview using a structured questionnaire consisted of socio demographics, working conditions, and the Standardized Nordic Questionnaire for musculoskeletal symptoms assessment during the period between April and May 2022. Descriptive statistics was used to present the prevalence of …


Chitosan/Biphasic Calcium Phosphate Composite Scaffold Incorporated With Trichostatin A For Bone Regeneration, Teerawat Sukpaita Jan 2021

Chitosan/Biphasic Calcium Phosphate Composite Scaffold Incorporated With Trichostatin A For Bone Regeneration, Teerawat Sukpaita

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study synthesized a chitosan-based scaffold incorporated with trichostatin A (TSA), an epigenetic modifier molecule, using a freeze-drying technique to achieve promising bone regeneration potential. The scaffolds with various biphasic calcium phosphate (BCP) proportions: 0%, 10%, 20%, and 40% were characterized. The addition of BCP improved the scaffolds' mechanical properties and delayed the degradation rate. From all physicochemical parameters, 20% BCP scaffold matched the appropriate bone scaffold requirements and was selected for further development. The proper concentration of TSA was also tested. Our developed scaffold released TSA and sustained them for up to 3 days. The scaffold with 800 nM …


การเปรียบเทียบสมบัติเชิงกลของซิลิโคนอีลาสโตเมอร์ในงานบูรณะใบหน้าและขากรรไกร ก่อนและหลังได้รับพลังงานไมโครเวฟ, เพ็ญชนก แสนทวีสุข Jan 2021

การเปรียบเทียบสมบัติเชิงกลของซิลิโคนอีลาสโตเมอร์ในงานบูรณะใบหน้าและขากรรไกร ก่อนและหลังได้รับพลังงานไมโครเวฟ, เพ็ญชนก แสนทวีสุข

Chulalongkorn University Theses and Dissertations (Chula ETD)

วัตถุประสงค์ของงานวิจัยเพื่อศึกษาสมบัติเชิงกลของซิลิโคนอีลาสโตเมอร์ในงานประดิษฐ์ ใบหน้าและขากรรไกรชนิด VST-50 และ M511 ที ่ใส่เม็ดสีและไม่ใส่เม็ดสี ก่อนและหลังได้รับการ แช่ในน้ำที ่ทำให้ร้อนด้วยพลังงานจากเตาไมโครเวฟโดยจำลองการใช้เตาไมโครเวฟ 18 เดือน ชิ ้นงานตัวอย่าง 80 ชิ ้นต่อซิลิโคนแต่ละชนิด ทั ้งหมด 160 ชิ ้น จัดเป็น 2 กลุ ่มตามการเติมเม็ดสีคือ ชิ ้นงานที ่ไม่มีสีและชิ ้นงานมีสี โดยเป็นเม็ดสีชนิดซิลิโคน และแบ่งออกเป็นกลุ ่มควบคุมและกลุ ่มเข้า เตาไมโครเวฟ รูปร่างชิ ้นงานถูกขึ ้นรูปตามมาตรฐาน ASTM D412 และ D624 ทั ้งหมดมี 8 กลุ่ม ย่อย (n=10) ต่อซิลิโคนแต่ละชนิด การนำชิ ้นงานเข้าไมโครเวฟร่วมกับการแช่น้ำ เป็นเวลา 6 นาที ที่ 660 วัตต์ 18 ครั ้ง เป็นการจำลองการใช้งานเดือนละ 1 ครั ้ง อุณหภูมิของน้ำภายหลังการเข้า ไมโครเวฟคือ 60 องศาเซลเซียส จากการวิเคราะห์ความแปรปรวนแบบ 2 ทาง (a=.5) พบว่า ซิลิโคน VST-50 ชนิดของเม็ดสีมีผลต่อความทนต่อแรงดึงและความแข็งของชิ ้นงานซิลิโคนอย่างมี นัยสำคัญทางสถิติ (P<.001) ทั ้งกลุ ่มควบคุมและเข้าเตาไมโครเวฟ ขณะที ่การใช้เตาไมโครเวฟมีผล ต่อความทนต่อการฉีกขาดอย่างมีนัยสำคัญทางสถิติ (P<.05) ทั ้งกลุ ่มไม่มีสีและมีสี และทั ้งสอง ปัจจัยไม่มีผลต่อร้อยละการยืดตัว ขณะที ่ซิลิโคน M511 มีปฏิสัมพันธ์กันระหว่างปัจจัยการผสมเม็ด สีและการเข้าไมโครเวฟอย่างมีนัยสำคัญทางสถิติสำหรับความแข็ง (P<.05)


ผลการคืนกลับแร่ธาตุบนรอยผุชั้นเนื้อฟันโดยการฉายแสงบนซิลเวอร์ไดเอมีนฟลูออไรด์, จุฑารัตน์ เผื่อนสุริยา Jan 2021

ผลการคืนกลับแร่ธาตุบนรอยผุชั้นเนื้อฟันโดยการฉายแสงบนซิลเวอร์ไดเอมีนฟลูออไรด์, จุฑารัตน์ เผื่อนสุริยา

Chulalongkorn University Theses and Dissertations (Chula ETD)

การศึกษาในห้องปฏิบัติการนี้มีวัตถุประสงค์เพื่อศึกษาประสิทธิภาพในการคืนกลับแร่ธาตุบนรอยผุ จำลองชั้นเนื้อฟันของการฉายแสงและไม่ฉายแสงภายหลังการทาสารละลายซิลเวอร์ไดเอมีนฟลูออไรด์ (SDF) ที่ ระยะเวลาแตกต่างกัน โดยนำชิ้นฟันตัวอย่างที่ได้จากการตัดแบ่งฟันกรามแท้แต่ละซี่เป็น 4 ชิ้นมาสร้างรอยผุ จำลองบนชั้นเนื้อฟันและสุ่มเข้า 4 กลุ่มทดลองคือ กลุ่ม SDF60 (n=10) ทา SDF 60 วินาที กลุ่ม SDF10 (n=10) ทา SDF 10 วินาที กลุ่ม SDF60+LC (n=10) ทา SDF 60 วินาทีร่วมกับการฉายแสงเป็นเวลา 20 วินาที และ กลุ่ม SDF10+LC (n=10) ทา SDF 10 วินาทีร่วมกับการฉายแสงเป็นเวลา 20 วินาที จากนั้นนำมาผ่านสภาวะ ช่องปากจำลองที่มีการจำลองสภาวะการสูญเสียและคืนกลับแร่ธาตุด้วยเชื้อแบคทีเรียเป็นเวลา 7 วัน ชิ้นฟัน ตัวอย่างก่อนทดลองและหลังทดลองถูกนำมาสแกนด้วยเครื่องเอ็กซ์เรย์คอมพิวเตอร์ระดับไมโครเมตร (MicroCT) เพื่อวิเคราะห์ค่าร้อยละการเปลี่ยนแปลงความลึกรอยผุเฉลี่ย (%LD change) และร้อยละการเปลี่ยนแปลง ความหนาแน่นแร่ธาตุเฉลี่ย (%MD change) ผลการทดลองพบว่า ปัจจัยการฉายแสงและปัจจัยระยะเวลาในการ ทาสารมีผลต่อประสิทธิภาพในการคืนกลับแร่ธาตุของ SDF แต่ทั้งสองปัจจัยไม่มีปฏิสัมพันธ์ระหว่างกัน (p=0.388 และ p=0.576) เมื่อเปรียบเทียบผล %LD change และ %MD change พบว่ากลุ่มที่มีการฉายแสง (กลุ่ม SDF60+LC และ SDF10+LC) ส่งเสริมให้สาร SDF มีประสิทธิภาพในการคืนกลับแร่ธาตุสูงกว่ากลุ่มที่ไม่ฉายแสง (กลุ่ม SDF60 และ SDF10) (p=0.008 และ p=0.026) ส่วนกลุ่มที่ทา SDF เป็นเวลา 60 วินาที (กลุ่ม SDF60 และ SDF60+LC) มีประสิทธิภาพในการคืนกลับแร่ธาตุดีกว่ากลุ่มที่ทา SDF เป็นเวลา 10 …


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การพัฒนาไบโอเซรามิกรูทคาแนลซีลเลอร์, สุรีย์พร โอฬารสกุลวงศ์

Chulalongkorn University Theses and Dissertations (Chula ETD)

การศึกษานี้มีวัตถุประสงค์เพื่อเปรียบเทียบคุณสมบัติทางกายภาพและองค์ประกอบทางเคมีของไบโอเซรามิกรูทคาแนลซีลเลอร์ที่ผลิตจากเปลือกหอยแครง (ไบโอซีลเลอร์) กับไบโอเซรามิกรูทคาแนลซีลเลอร์ซึ่งมีจำหน่ายในท้องตลาด (ไอรูทเอสพี) โดยทำการสังเคราะห์ผงไตรแคลเซียมซิลิเกตจากเปลือกหอยแครง และตรวจสอบองค์ประกอบทางเคมีด้วยการทดสอบการเลี้ยวเบนของรังสีเอกซ์ ผลการทดสอบพบว่าสารที่ผลิตได้ประกอบด้วยไตรแคลเซียมซิลิเกตเป็นส่วนประกอบหลัก จากนั้นจึงนำมาผสมกับสารเติมแต่งเพิ่มเติมเพื่อผลิตเป็นไบโอซีลเลอร์ ทำการทดสอบคุณสมบัติทางกายภาพของไบโอซีลเลอร์และไอรูทเอสพีตามมาตรฐานการทดสอบไอเอสโอ 6876/2012 ได้แก่ การไหลแผ่ เวลาแข็งตัว ความหนาชั้นฟิล์ม การละลายตัว และความทึบรังสี นอกจากนี้ได้ทำการศึกษาค่าความเป็นกรด-ด่าง และปริมาณแคลเซียมอิออนที่ถูกปล่อยออกมาที่ระยะเวลา 3 ชั่วโมง 1 วัน 3 วัน 7 วัน 14 วัน และ 28 วัน รวมถึงศึกษาองค์ประกอบทางเคมีหลังแข็งตัวเต็มที่ของซีลเลอร์ทั้งสอง คุณสมบัติทางกายภาพของไบโอซีลเลอร์และไอรูทเอสพีมีค่าผ่านตามมาตรฐานไอเอสโอ 6876/2012 ยกเว้นคุณสมบัติด้านการละลายตัว สำหรับค่าความเป็นกรด-ด่างของไบโอซีลเลอร์และไอรูทเอสพีในช่วงระยะเวลาที่ทำการทดสอบพบว่ามีค่า 9.23-10.35 และ 8.83-10.39 ตามลำดับ ส่วนปริมาณแคลเซียมอิออนที่ถูกปล่อยออกมาพบว่าไอรูทเอสพีปล่อยแคลเซียมอิออนมากกว่าไบโอซีลเลอร์อย่างมีนัยสำคัญทางสถิติในช่วงแรกแต่ไม่แตกต่างกันที่ช่วงระยะเวลา 14 และ 28 วัน นอกจากนี้การศึกษาองค์ประกอบทางเคมีของไบโอซีลเลอร์และไอรูทเอสพีหลังแข็งตัวเต็มที่พบองค์ประกอบที่ยืนยันการเกิดปฏิกิริยาไฮเดรชันของวัสดุ ดังนั้นจึงสามารถสรุปได้ว่าไบโอซีลเลอร์มีคุณสมบัติทางกายภาพที่ดีและมีคุณสมบัติใกล้เคียงกับไอรูทเอสพี