Digital Commons Network^™

Associations Of Sars-Cov-2 Serum Igg With Occupation And Demographics Of Military Personnel, Joseph Zell

Public Health Theses

BACKGROUND: Countries across the globe have mobilized their armed forces in response to COVID-19, placing them at increased risk for viral exposure. Humoral responses to SARS-CoV-2 among military personnel serve as biomarkers of infection and provide a basis for disease surveillance and recognition of work-related risk factors.METHODS: Enzyme-linked immunosorbent assays (ELISA) were used to measure SARS-CoV-2 spike antigen-specific IgG in serum obtained from N-995 US Army and Air National Guard soldiers between April and June 2020. Occupational information, e.g. military operating specialty (MOS) codes, and demographic data were obtained via questionnaire. Plaque assays with live SARS-CoV-2 were used to assess …

Identification Of Genetic Factors For Metabolically Healthy Obese And Metabolically Obese Normal-Weight, Junli Zhu

Public Health Theses

Though obesity is typically associated with metabolic dysfunction and cardiometabolic diseases, there are both obese individuals who have favorable metabolic profiles (metabolically healthy obese; MHO) and individuals who present obesity alterations despite their normal weight (metabolically obese normal weight; MONW). Genetic studies suggest that there is a genetic component underlying these phenotypes. However, previous research has been restricted by the use of the candidate gene approach, limited choice of metabolic indicators, and low statistical power. A genome-wide association (GWA) study that examines both MHO and MONW in a single large-scale population cohort is necessary to uncover the genetic determinants of …

What Will Be Enough? Suicide Prevention Challenges Of A Parking Garage, Shirley Zhen

Public Health Theses

Objectives: This project assesses deaths by jumping at a prominent parking garage in New Haven, CT in order to improve upon structural suicide prevention efforts.Methods: Individuals and organizations potentially involved with the garage were identified and contacted for information regarding any previous suicide prevention efforts, reasons for lack of prior interventions, and any existing or future plans for structural interventions. Physical evaluation of the garage was assessed for accessibility to the rooftop level and features that potentially contribute to the location as a jumping site. Data on suicide deaths was gathered from news reports and the CT Chief Medical Examiner …

Htra1 Expression In Humanized Arms2 Knock-In Mouse Models, Yunfan Zhang

Public Health Theses

Age-related macular degeneration (AMD) is the most common cause of central vision loss in developed world. Two genes on chromosome 10q26, maculopathy susceptibility 2 (ARMS2) and HtrA serine peptidase 1 (HTRA1) were identified as candidate genetic factors of AMD. However, due to the high linkage disequilibrium across the locus as well as the inconsistent functional findings regarding the two genes, it is difficult to distinguish the causative gene that confer the risk of AMD. To provide insight of the functional roles of ARMS2 and HTRA1 in the pathogenesis of AMD, we investigated the regulation relationship between the two genes in …

Simultaneous Wound Border Segmentation And Tissue Classification Using A Conditional Generative Adversarial Network, Salih Sarp, Murat Kuzlu, Manisa Pipattanasomporn, Ozgur Guler

Engineering Technology Faculty Publications

Generative adversarial network (GAN) applications on medical image synthesis have the potential to assist caregivers in deciding a proper chronic wound treatment plan by understanding the border segmentation and the wound tissue classification visually. This study proposes a hybrid wound border segmentation and tissue classification method utilising conditional GAN, which can mimic real data without expert knowledge. We trained the network on chronic wound datasets with different sizes. The performance of the GAN algorithm is evaluated through the mean squared error, Dice coefficient metrics and visual inspection of generated images. This study also analyses the optimum number of training images …

The Enlightening Role Of Explainable Artificial Intelligence In Chronic Wound Classification, Salih Sarp, Murat Kuzlu, Emmanuel Wilson, Umit Cali, Ozgur Guler

Engineering Technology Faculty Publications

Artificial Intelligence (AI) has been among the most emerging research and industrial application fields, especially in the healthcare domain, but operated as a black-box model with a limited understanding of its inner working over the past decades. AI algorithms are, in large part, built on weights calculated as a result of large matrix multiplications. It is typically hard to interpret and debug the computationally intensive processes. Explainable Artificial Intelligence (XAI) aims to solve black-box and hard-to-debug approaches through the use of various techniques and tools. In this study, XAI techniques are applied to chronic wound classification. The proposed model classifies …

Opportunistic Maintenance Strategy Of A Heave Compensation System For Expected Performance Degradation, Chao Zhang, Yujie Qian, Hongyan Dui, Shaoping Wang, Rentong Chen, Mileta M. Tomovic

Engineering Technology Faculty Publications

In the marine industry, heave compensation systems are applied to marine equipment to compensate for the adverse effects of waves and the hydraulic system is usually used as the power system of heave compensation systems. This article introduces importance theory to the opportunistic maintenance (OM) strategy to provide guidance for the maintenance of heave compensation systems. The working principle of a semi-active heave compensation system and the specific working states of its hydraulic components are also first explained. Opportunistic maintenance is applied to the semi-active heave compensation system. Moreover, the joint integrated importance measure (JIIM) between different components at different …

Biocybersecurity: A Converging Threat As An Auxiliary To War, Lucas Potter, Orlando Ayala, Xavier-Lewis Palmer

Engineering Technology Faculty Publications

Biodefense is the discipline of ensuring biosecurity with respect to select groups of organisms and limiting their spread. This field has increasingly been challenged by novel threats from nature that have been weaponized such as SARS, Anthrax, and similar pathogens, but has emerged victorious through collaboration of national and world health groups. However, it may come under additional stress in the 21st century as the field intersects with the cyberworld-- a world where governments have already been struggling to keep up with cyber attacks from small to state-level actors as cyberthreats have been relied on to level the playing field …

Crypto Coin Offerings And The Freedom Of Expression, Hannibal Travis

Chapman Law Review

In his Article, Professor Travis argues that the freedom of expression protects crypto coin software and related economic and technical speech from being treated like a simple offering of stock in a bank or an oil company. The Article lays out how crypto coin white papers are not strictly commercial speech, and blockchain networks are not traditional corporations or limited partnerships, but rather that crypto coins and their white papers promote information sharing, open-source software, insights in computer science and peer-to-peer networking technologies, and new socio-economic and political models of decentralized collaboration.

The Crisis Of Chad: Men’S Rights Movements And Contemporary Anti-Feminism, Kendrick Zapata

Dissertations and Theses

This thesis analyzes the relationship between the modern incel and manosphere movement, and its historical legacies in anti-feminist discourses in late 20th century men's rights movements. The manosphere is a collection of online videos, forums, blogs, and websites dedicated to raising awareness or promoting masculinist philosophies. Incels in particular are individuals that understand their lack of sexual interaction as inherent, and often interact in digital spaces with others. Incel beliefs range from calling for the reversal of women’s rights, to seeking advice on self-improvement forums that offer advice to young men seeking to improve their physique through diet and exercise. …

Ethnic Politics And Constitutional Developments In Nigeria, Nancy Ojochogwu Oji

Dissertations and Theses

This project attempts to study Nigeria's colonial political parties and the consequences of British colonial policies as the foundation of ethnic issues in Nigeria's contemporary politics. It describes how particular colonial policies impact modern Nigerian politics, reinforce division among ethnic groups, and influence voters’ decision when electing political leaders.

The Contribution Of Adverse Childhood Experiences To The Interplay Between Insecure Attachment Characteristics, Trait Emotional Intelligence, Difficulties In Emotion Regulation, And Personality Organization, Kseniia Gvozdieva

Dissertations and Theses

There are well-established connections between unfavorable attachment experiences and subsequent personality pathology. Individuals with adverse attachment experiences and those with personality pathology have been found to have difficulty with emotional awareness and emotion regulation. Attachment characteristics inform emotional intelligence and emotion regulation, while emotional intelligence and emotion regulation capacities can be protective against personality pathology and serve as a potential mechanism of positive change in one’s attachment. Complex trauma disrupts attachment and the subsequent development of emotional intelligence, emotion regulation, as well as personality structure.

In this dissertation, we examine the ways in which individual attachment patterns can be linked …

Osteocyte Activity And Skeletal Muscle Relative Gene Expression Profiling After Short-Term Muscle Paralysis, Michelle Gelbs

Dissertations and Theses

Mechanical loading is essential for maintaining bone tissue. Reduced mechanical loading has been shown to have a negative effect on bone, and can result in the development of disuse osteoporosis. Disuse models of muscle inactivity and immobilization, like the Botox model used in this study, result in changes in the bone microarchitecture, the mechanisms behind which are not fully understood. In a previous four-week Botox disuse study, skeletally mature 20- week-old rats experienced degradation of intracortical bone, increased vascular porosity, and decreased osteocyte lacunar density in the tibiae. The focus of this study was to explicate a potential source of …

Development Of An Injectable Methylcellulose Hydrogel System For Nucleus Pulposus Repair And Regeneration, Nada A. Haq-Siddiqi

Dissertations and Theses

Low back pain is the most common cause of disability in the world and is often caused by degeneration or injury of the intervertebral disc (IVD). The IVD is a complex, fibrocartilaginous tissue that allows for the wide range of spinal mobility. Disc degeneration is a progressive condition believed to begin in the central, gelatinous nucleus pulposus (NP) region of the tissue, for which there are few preventative therapies. Current therapeutic strategies include pain management and exercise, or surgical intervention such as spinal fusion, none of which address the underlying cause of degeneration. With an increasingly aging population, the socioeconomic …

Examining Cultural Orientation As A Moderator: Attachment Style, Forgiveness, And Depression, Linghsi Liu

Dissertations and Theses

The purpose of this study was to examine the moderating role of cultural orientation on the relation between attachment style and forgiveness and between forgiveness and depression. It was hypothesized that a secure attachment style would be associated with greater dispositional forgiveness of both self and others. Specifically, for those high in collectivism, insecure attachment will be associated with greater other-forgiveness and for those high in individualism, insecure attachment will be associated with greater self-forgiveness. It was also predicted that self and other forgiveness would be associated with fewer depressive symptoms. Specifically, for those high in collectivism, other forgiveness will …

Does Social Media Promote Disordered Eating?, Carly Feldstein

Dissertations and Theses

Hispanic people are the largest and fastest-growing minority group in the U.S. with a total of 18.5% of the U.S population being of Hispanic descent (United States Census Bureau, 2020). Although eating disorders (ED), particularly those involving binge eating, comprise a significant health concern, EDs are often overlooked in the Hispanic culture (Higgins et al., 2016; Opara & Santos, 2019). Hispanic individuals have comparable rates of anorexia nervosa, bulimia nervosa, and an even higher rate of binge eating disorders compared to non- Hispanic (NH) White individuals (Higgins et al., 2016). Within Hispanic adults, the lifetime prevalence of EDs is higher …

A Review Of Data Protection Regulations And The Right To Privacy: The Case Of The Us And India, Chrisann Campbell

Dissertations and Theses

Since 1948 and the signing of the Universal Declaration of Human Rights, the concept of privacy has grown more complex with the rise of technology and a shift to the internet. In particular, the unregulated use of technologies that can capture individuals' personal data without their knowledge or consent poses a threat to their right to privacy and other additional human rights. The protection of the collection, storing, and transfer of users' personal data against data breaches also ensures that the right to privacy is guaranteed. Through examining two countries, the U.S. and India, on the idea of privacy, personal …

China In Africa: Partner Or Exploiter? The Case Of Zambia, Chansa E. Mushota

Dissertations and Theses

Marked by investments, loans, and finance, China’s engagement in Africa has grown swiftly. Amongst sub-Saharan Africa’s many trading and developing partners, China remains the biggest partner and investor with an increase in trade relations.^[1] The China-Africa relationship has brought significant economic opportunities, but it has also generated controversy in the international community. China has been challenged by some of forming a partnership with African governments solely for China’s own interests. China provides low-interest loans to the African governments for development and infrastructure projects. However, China’s motives are exploitative as China uses economic and political pressures to influence African governments …

Therapist Feelings Of Incompetence: Their Relationship To The Working Alliance And Treatment Outcome., Benjamin Bernstein

Dissertations and Theses

This study set out to explore therapist feelings of incompetence (FOI) in the therapeutic process from both a quantitative and qualitative perspective. While previous studies have explored therapist descriptions of such feelings, this is among the first attempts to look at the role of these specific feelings in an individual therapy session using therapist and patient data. The results revealed that therapist feelings of incompetence impact the working alliance directly and outcome change indirectly, through the working alliance. Furthermore, qualitative analysis suggested that therapist feelings of incompetence might be associated with specific avoidant behaviors which may negatively impact the working …

The Push Factors That Impact Sex Trafficking In The Former Soviet Union, Liliya Kenzhebayeva

Dissertations and Theses

Sex trafficking is a global problem that has been denounced by the international community as a human rights abuse and determined to be a modern form of slavery. Through a comparative analysis of the experiences of Kazakhstan, Russia, and Ukraine as they were a part of the Soviet Union the study identifies the push factors of sex trafficking in women as forced labor with particular emphasis on the role of weak legal systems and state institutions, corruption, social and economic factors, and environmental problems that are linked to organized crime (the Russian mafia) from 2001 to 2019. The thesis supports …

Control Hierarchies For Critical Infrastructures In Smart Grid Using Reinforcement Learning And Metaheuristic Optimization, Oindrilla Dutta

Dissertations and Theses

The objective of this work is to develop robust control framework for interdependent smart grid infrastructures comprising two critical infrastructures: 1) power distribution networks that are characterized by high penetration of distributed energy resources (DERs), and 2) DC-rail transportation systems in congested urban areas. The rising integration of DERs into the power grid is causing a paradigm shift in the power distribution network. Consequently, new control challenges for efficient and robust operation of the power grid have surfaced. For instance, the intermittency of renewable energy resources necessitates coordinated control of power flows, voltage regulators, and protection device settings of the …

Investigating The Effect Of Electrolyte Concentration And Charging Protocol On Materials Utilization In Rechargeable Zinc Manganese Dioxide Batteries, Snehal H. Kolhekar

Dissertations and Theses

Achieving a highly cyclable, high energy density battery with MnO₂ cathodes encounters many obstacles. Chief among these is the inability of the widely-used γ-MnO₂ polymorph to retain its structural integrity when cycled to near full one-electron discharge capacity, which is about 280mAh/g for commercially available electrolytic manganese dioxide (EMD). In this one-electron range, discharge occurs by proton insertion producing Mn⁺³ which then reverts to γ-MnO₂ on charging. In the first part of the thesis, we investigate the root cause of failure of MnO₂ cathodes under deep cycling in the one-electron discharge range and establish a …

Incidence And Severity Of Drug Interactions Before And After Switching Antiretroviral Therapy To Bictegravir/Emtricitabine/Tenofovir Alafenamide In Treatment-Experienced Patients., Jason J. Schafer, Pharmd, Mph, Bcps, Aahivp, Neha S Pandit, Agnes Cha, Emily Huesgen, Melissa Badowski, Elizabeth M Sherman, Jennifer Cocohoba, Ayako Shimada, Scott W Keith

College of Pharmacy Faculty Papers

Background: Switching antiretroviral therapy (ART) in people with HIV (PWH) can influence their risk for drug-drug interactions (DDIs). The purpose of this study was to assess changes in the incidence and severity of DDIs among PWH who switched their ART to bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF).

Methods: This was a multicenter retrospective cohort study of PWH on ART and at least 1 concomitant medication (CM) who switched to BIC/FTC/TAF between 3/2018 and 6/2019. Using the University of Liverpool's HIV Drug Interaction Database, 2 DDI analyses were performed for each patient. The first assessed patients' preswitch ART regimens with their CM list. The …

Legislative Options To Address Institutional Objections To Voluntary Assisted Dying In Australia, Ben P. White, Lindy Willmott, Eliana Close, Jocelyn Downie

Articles, Book Chapters, & Popular Press

Voluntary assisted dying is being considered by parliaments and law reform bodies across Australia. Although individual conscientious objection is routinely considered in these deliberations, an institution’s desire to object to providing voluntary assisted dying has received very little attention. After briefly considering the concept of institutional objection in voluntary assisted dying, this article examines the available (albeit limited) Australian evidence on this practice. Institutional objection is happening in Victoria (where voluntary assisted dying is lawful) and is likely to occur in other Australian states. The article proposes that regulation is needed and presents three models for parliaments and law reformers …

The Diffuse Bounce Back Lattice Boltzmann Method And Its Applications On The Study Of Fluid-Particle Interactions, Geng Liu

Dissertations and Theses

Fluid-structure interaction is very broadly seen and widely used in many industrial, engineering and environmental processes. The lattice Boltzmann method has been preferred for simulating particulate flows due to its advantages of easy implementation, micro- and mesoscopic physical insights and parallel algorithm. Both sharp and diffuse boundary treatments are studied to recover curved and moving boundaries on structured orthogonal grids for the lattice Boltzmann method. These methods can describe curved boundaries more accurately and more smoothly than the naive staircase approximation. However, to improve the order of velocity accuracy and to reduce the fluctuation of force, either interpolation or additional …

Resource Curse In Kenya’S Coastal Region: A Symptom Of Institutional Failure, George Atisa

Public Affairs and Security Studies Faculty Publications

Regions endowed with abundant natural resources are expected to thrive economically, but this is not the case for Kenya’s coastal region. Communities in this region believe they are working hard enough but are still held in abject poverty by circumstances not of their own making. This state of development raises one pertinent question – who is responsible for this poor state of development and rampant poverty? When it is about an individual, it is easy to attach success to talent and hard work, and sometimes sheer luck, but it is difficult to generalize the “hard-working” argument to an entire community …

Regulating Wave, Tidal And Ocean Thermal Energy, Meinhard Doelle, Theodore Nsoe Adimazoya

Articles, Book Chapters, & Popular Press

Ocean renewable energy sources hold the potential to contribute to the options of low-carbon energy sources and enhance the efforts by the global community to slow down climate change. In this Chapter, we provide a brief background on the current state of technology and development of wave, tidal and ocean thermal energy and consider their potential as forms of renewable energy as well as the potential negative environmental footprints of ocean renewable energy installation and development. Secondly, we examine the relevant international legal and policy framework governing ocean energy, highlighting in particular, the absence of a global legal instrument that …

Articulator Q1 2021

Metro Denver Dental Society Articulator Magazine

The MDDS Articulator magazine has been serving as the voice for Denver's dental community for over 100 years.

Distributed to approximately 2,000 dental professionals quarterly, the Articulator features local news, industry trends, practice management guidance, data-driven research and more. The award-winning publication is available to member dentists in both print and digital forms.

Issues include cover and feature articles alongside regular columns with regional news impacting the Metro Denver membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

N Y State Dent J January 2021

The New York State Dental Journal

The New York State Dental Journal (NYSDJ) is produced by the New York State Dental Association (NYSDA) six times a year, in January, March, April, July, September and November. Each issue features clinical and scientific articles written by researchers and practitioners from around the globe and is subject to review by a panel of specialists convened by the Editor.

Issues include cover and feature articles alongside regular columns with regional news impacting the New York membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Articulator Q2 2021

Metro Denver Dental Society Articulator Magazine

The MDDS Articulator magazine has been serving as the voice for Denver's dental community for over 100 years.

Distributed to approximately 2,000 dental professionals quarterly, the Articulator features local news, industry trends, practice management guidance, data-driven research and more. The award-winning publication is available to member dentists in both print and digital forms.

Issues include cover and feature articles alongside regular columns with regional news impacting the Metro Denver membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.