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Association Of Physical Frailty With Cognitive Function And Mood In Older Adults Without Dementia And Depression, Rana Tuna Doğrul, Hacer Doğan Varan, Muhammet Cemal Kizilarslanoğlu, Mustafa Kemal Kiliç, Özgür Kara, Güneş Arik, Meltem Gülhan Hali̇l, Mustafa Cankurtaran, Burcu Balam Doğu

Turkish Journal of Medical Sciences

Background/aim: Physical frailty is thought to be related with a decline in cognitive function, mood, and social activities, especially in patients with depression and dementia. It is not clear whether or not physical frailty is associated with an impairment in cognitive function and mood in patients without dementia and depression. In this study, we evaluated the association of physical frailty with cognitive function and mood in geriatric patients without dementia and depression. Material and methods: In this study, 612 patients aged 65 years and over were evaluated. Physical frailty was assessed by using Fried criteria. Furthermore, comprehensive geriatric assessment was …

Evaluation Of Ambulance Calls For Patients Over 65 Years Of Age In İzmir, Turkey: A Twoyear Retrospective Analysis, Ahu Pakdemi̇rli̇, Başak Bayram, Erkan Güvenç, Hülya Elli̇dokuz

Turkish Journal of Medical Sciences

Background/aim: Analysis of interventions for special patient groups is important for the planning of health services, especially emergency medical services. In this study, we aimed to evaluate emergency medical service (EMS) interventions for the elderly and determine the decisive factors affecting transfer to the hospital of EMS team over 2 years (2017 and 2018) in İzmir. Materials and methods: Records of 112 emergency calls that were made between 2017 and 2018 followed up with interventions for patients aged 65 years and older were obtained from the 112 system. The reasons for the calls, outcomes, possible diagnoses of the patients, differences …

Impact Of Frailty And Ultrasonography-Based Sarcopenia On The Development Ofpostoperative Complications In Gastrointestinal Cancer Patients, Gözde Şengül Ayçi̇çek, Ti̇muçi̇n Erol, Peli̇n Ünsal, Olgun Deni̇z, Osman Abbasoğlu, Meltem Gülhan Hali̇l

Turkish Journal of Medical Sciences

Background/aim: Gastrointestinal (GI) system cancers are frequent among older adults and it is still difficult to predict which are at increased risk for postoperative complications. Frailty and sarcopenia are increasing problems of older population and may be associated with adverse outcomes. In this study we aimed to examine the effect of sarcopenia and frailty on postoperative complications in older patients undergoing surgery for GI cancers. Materials and methods: Forty-nine patients admitted to general surgery clinic with the diagnosis of gastrointestinal system cancers were included in this cross-sectional study. Frailty status was assessed using the Edmonton Frail Scale (EFS). Sarcopenia was …

An Investigation Of The Factors That Influence Functional Improvement In Strokerehabilitation, Onur Altuntaş, Serkan Taş, Alp Çeti̇n

Turkish Journal of Medical Sciences

Background/aim: The purpose of this study was to determine effect of age, sex, affected extremity, disability severity, treatment type, cerebrovascular accident (CVA) etiology, number of treatment sessions, and CVA duration on the functional improvement of the stroke patients who participated in a physical medicine and rehabilitation program. Materials and methods: The research sample consisted of 322 stroke patients. Clinical and demographic features including age, sex, affected extremity, disability severity, treatment type, CVA etiology, number of treatment sessions, and CVA duration were recorded. Functional status was evaluated retrospectively by using the functional independence measure (FIM) at admission and discharge. Results: It …

Lutein/Zeaxanthin Isomers Regulate Neurotrophic Factors And Synaptic Plasticity Intrained Rats, Cemal Orhan, Füsun Erten, Beşi̇r Er, Mehmet Tuzcu, Nurhan Şahi̇n, Öznur Ece Durmaz Kurşun, Vijaya Juturu, Kazi̇m Şahi̇n

Turkish Journal of Medical Sciences

Background/aim: This study was conducted to elucidate the effects of lutein/zeaxanthin isomers (L/Zi) on lipid metabolism, oxidative stress, NF-ΚB/Nrf2 pathways, and synaptic plasticity proteins in trained rats. Materials and methods: Wistar rats were distributed into four groups: 1) control, 2) L/Zi: rats received L/Zi at the dose of 100 mg/kg by oral gavage, 3) exercise, 4) exercise+L/Zi: rats exercised and received L/Zi (100 mg/kg) by oral gavage. The duration of the study was eight weeks. Results: Exercise combined with L/Zi reduced lipid peroxidation and improved antioxidant enzyme activities of muscle and cerebral cortex in rats (p < 0.001). In the Exercise + L/Zi group, muscle and cerebral cortex Nrf2 and HO-1 levels increased, while NF-ΚB levels decreased (p

Immunoglobulins And Acute Phase Proteins In Van Cats - Associations With Sex, Age, Andeye Colour, Pinar Coşkun, Vahdetti̇n Altunok, Fi̇li̇z Kazak, Nazmi̇ Yüksek

Turkish Journal of Veterinary & Animal Sciences

It was aimed to determine concentrations of plasma immunoglobulins (IgG, IgA, IgM) and acute phase proteins (?-1 acid glycoprotein, serum amyloid A, ceruloplasmin) and the association of these parameters with age, sex, and eye colour in Van cats. Blood plasma of healthy, forty-seven Van cats (Van Cat Home) fed with standard cat food were involved in the study. Cats were divided into four groups based on age ( 5) and eye colour (amber-amber, amber-blue, blue-amber, and blue-blue eyes described from left to right), and two groups based on sex (male and female). Plasma IgG, IgA, IgM, ?-1 acid glycoprotein, serum …

The Role Of Privacy Within The Realm Of Healthcare Wearables' Acceptance And Use, Thomas Jernejcic, Omar El-Gayar

Research & Publications

While there are definite benefits attributed to wearables, there are also notable risks, especially in the realm of security where personal information and/or activities are often accessible to third parties. Users weigh the benefits with the risks (Privacy Calculus) and often opt for the wearable device despite concern that their information may or will be disclosed (Privacy Paradox). While past research has focused on specific technologies, the paradox of disclosure despite concern for privacy has not been the primary focus, particularly regarding the manifestation of the paradox specific to the acceptance and use of healthcare wearables. The purpose of this …

Predictors Of Utilization Of Care In A Community Outpatient Mental Health Sample, Matthew F. Bloom

PCOM Psychology Dissertations

The term superutilizer is used to classify individuals who frequent emergency departments and inpatient medical settings for preventable reasons. The exact criteria for this term are unclear, and there is dearth of literature on how it applies to the outpatient medical setting and to mental health utilization. The purpose of this study was to identify potential client demographic and clinical variables predictive of the utilization of mental health services/resources, as measured by number of sessions attended over the course of treatment in an outpatient mental health setting. It was hypothesized there would be a predictive relationship between being female, younger, …

Undergraduate Course Catalog Of The University Of San Diego 2021-2022, University Of San Diego

Undergraduate Course Catalogs (1973- )

845 pages. Includes information about academics, expenses, campus and the college, the 2021-2022 academic calendar, and school policies.

University Of San Diego Graduate Course Catalog 2021-2022, University Of San Diego

Graduate Course Catalogs (1971-)

304 pages

Performance-Based Iadl Evaluation Of Older Adults With Cognitive Impairment Within A Smart Home: A Feasibility Study, Iris Rawtaer, Khalid Abdul Jabbar, Xiao Liu, Thit Thit Htat Ying, Anh Thuy Giang, Philip Lin Kiat Yap, Rachel Chin Yee Cheong, Hwee-Pink Tan, Pius Lee Wei Qi, Shiou Liang Wee, Tze Pin Ng

Research Collection School Of Computing and Information Systems

Introduction Mild cognitive impairment (MCI) is characterized by subtle deficits that functional assessment via informant-report measures may not detect. Sensors can potentially detect deficits in everyday functioning in MCI. This study aims to establish feasibility and acceptability of using sensors in a smart home for performance-based assessments of two instrumental activities of daily living (IADLs). Methods Thirty-five older adults (>65 years) performed two IADL tasks in a smart home laboratory equipped with sensors and a web camera. Participants' cognitive states were determined using published criteria including measures of global cognition and comprehensive neuropsychological test batteries. Selected subtasks of the …

Subjective Social Status And Inflammation: The Role Of Culture And Anger Control, Jose C. Yong, Andree Hartanto, Jacinth Jia Xin Tan

Research Collection School of Social Sciences

Objective: Research on subjective social status (SSS) and inflammation risk suffers from a lack of cross-cultural data as well as inconsistent findings between SSS and the biomarker C-reactive protein (CRP). The current study addressed these issues by examining possible cultural differences in the SSS-CRP link with anger control as an underlying mechanism while controlling for potential confounds such as wealth, education, and health factors. Method: Participants comprised 1,435 adults from the Biomarker Project of the MIDUS (American) and MIDJA (Japanese) studies. Participants’ SSS and tendency to control anger were assessed through surveys, and their CRP levels were measured through fasting …

The Facets Of Meaningful Experiences: An Examination Of Purpose And Coherence In Meaningful And Meaningless Events, William Tov, Weiting Ng, Soon-Hock Kang

Research Collection School of Social Sciences

Research on meaning has begun to assess the specific facets of meaning in life. Few studies have examined the extent to which these facets distinguish meaning at the level of individual events. In the present study, participants from Singapore and the U.S. wrote about meaningful and meaningless events and rated the extent to which they experienced purpose, coherence, positive and negative implications for self and others, positive affect, and negative affect. In both samples, meaningful and meaningless events differed most in their levels of positive affect, purpose, and positive implications for the self. When entered as predictors of overall event …

Undergraduate Catalog, Georgia Southern University

Undergraduate & Graduate Catalogs

No abstract provided.

The Stressors Faced By Retail Workers During The Covid-19 Pandemic, Nada Elnahla, Leighann C. Neilson

AMTP Proceedings 2021

Amidst the COVID-19 pandemic, brick-and-mortar retail workers have been hailed as heroic frontline employees. No matter where a retail store is located or the severity of the lockdown, retail workers have many new regulations and guidelines to follow and implement in order to protect both themselves and their customers. Using a qualitative research methodology, this exploratory research focuses on how the COVID-19 pandemic and its resulting drastic changes in the retail sector are affecting the workers in North America. Four main stressors are identified: fear of the unknown, fear of infection, mistreatment by consumers, and the role of the powerless …

The Validation Of Predicted Biological Age Of Drosophila Melanogaster From Combined Statistical Modeling, Lauren Francis

Masters Theses

"Sleep is essential for maintaining a healthy body and mind and is associated with aging and aging related diseases. There are individual differences in fly as well as human sleep behavior and lifespan. Between and within individuals, sleep varies in characteristics including consolidation, rhythmicity, continuity, duration, and more. Various evidence in the literature suggests there are many molecular pathways involved with aging and they may be different for individuals. Our research is interested in a possible restorative mechanism of sleep and the ramifications of that mechanism to aging. We have developed two predictive models of aging using the fruit fly …

The Flame, 2021-2022, Mennonite College Of Nursing

The Flame (1985-present)

The Flame is a newsletter of Illinois State University's Mennonite College of Nursing

Dimensional Latent Structure Of Icd-11 Posttraumatic Stress Disorder, Complex Ptsd, And Adjustment Disorder: Evidence From Ghana, Kenya, And Nigeria, Ruby Charak, Ines Cano-Gonzalez, Mark Shevlin, Menachem Ben-Ezra, Thanos Karatzias, Philip Hyland

Psychological Science Faculty Publications

With the release of ICD-11 in 2018, there has been a surge in studies examining the nosology of mental disorders, including disorders associated with stress, namely, posttraumatic stress disorder (PTSD), complex PTSD (CPTSD), and adjustment disorder (AjD). Few studies have examined the same in low- and middle-income countries that have disproportionate levels of exposure to trauma and stressors and are under-resourced in mental health services. The present study examined the latent factor structure of a joint model comprising PTSD, CPTSD, and AjD symptoms and their association with stressful and traumatic life events to assess the degree of distinctiveness between these …

A Systematic Review And Psychometric Evaluation Of Self-Report Measures For Hoarding Disorder, Clarissa W. Ong, Jennifer Krafft, Michael E. Levin, Michael P. Twohig

Psychology Student Research

Background: Hoarding disorder (HD) affects approximately 2.5% of the general population, leads to significant distress and impairment, and is notoriously difficult to treat. The crux of developing effective treatments for HD is our ability to reliably and validly measure relevant constructs in HD to better understand its presentation and, subsequently, formulate appropriate interventions.

Methods: We identified measures specific to HD and evaluated their psychometric properties using rating criteria formulated by the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) group.

Results: The 17 included measures were developed to assess adult and pediatric hoarding severity, functional impairment, and maladaptive …

Sleep, Health, And Wellbeing Among Middle-Aged And Older Adults: Impact Of Insomnia Symptoms On Incident Heart Failure, Cognitive Performance, And All-Cause Mortality, Asos Qadir Mahmood

Electronic Theses and Dissertations Archive

In this three-paper dissertation, we used longitudinal data from the Health and Retirement Study (HRS) to investigate prospective associations between time-varying insomnia symptoms (difficulty initiating sleep, difficulty maintaining sleep, early-morning awakening, non-restorative sleep) and incident heart failure (HF), cognitive impairmentno dementia (CIND), and all-cause mortality among middle-aged and older adults (aged 50 years). In each study, we implemented a marginal structural modeling approach to generate the average causal effects of insomnia symptoms, while taking into account time-dependent biological, psycho-cognitive, behavioral, and lifestyle factors, and adjustments for selection bias.The first paper employed data from the 2002 through 2018 waves of HRS, …

Denture Wearing Is Associated With Nutritional Status Among Older Adults Requiring Long-Term Care: A Cross-Sectional Study, Yuki Ohara, Ayami Meguro, Masanori Iwasaki, Ayako Edahiro, Maki Shirobe, Kentaro Igarashi, Keiko Motokawa, Masayasu Ito, Yutaka Watanabe, Yasuhiko Kawai, Hirohiko Hirano

Journal of Dental Sciences

Abstract Background/purpose Dentures are important for the reconstruction of occlusal support and masticatory performance for older adults with poor dentition. We aimed to elucidate the oral health factors associated with malnutrition in older adults requiring long-term care, including denture use. Materials and methods This cross-sectional study included 322 older adults (63 men, 259 women; mean age, 86.6 ± 6.9 years) who required long-term care in rural Japan. The participant's nutritional status was assessed using the Mini Nutritional Assessment-Short Form (MNA®-SF). Oral health was assessed using participant's dentition and oral function. Barthel Index (BI) and medical history were measured for assessing …

Potential Of Sorghum Polyphenols To Prevent And Treat Alzheimer's Disease: A Review Article, Nasim Rezaee, Warnakulasuriya Mary Ann Dipika Fernando, Eugene Hone, Hamid R. Sohrabi, Stuart K. Johnson, Stuart Gunzburg, Ralph Martins

Research outputs 2014 to 2021

Alzheimer’s disease (AD) is characterized by the excessive deposition of extracellular amyloid-beta peptide (Aβ) and the build-up of intracellular neurofibrillary tangles containing hyperphosphorylated tau proteins. This leads to neuronal damage, cell death and consequently results in memory and learning impairments leading to dementia. Although the exact cause of AD is not yet clear, numerous studies indicate that oxidative stress, inflammation, and mitochondrial dysfunction significantly contribute to its onset and progression. There is no effective therapeutic approach to stop the progression of AD and its associated symptoms. Thus, early intervention, preferably, pre-clinically when the brain is not significantly affected, is a …

The Development Of Aboriginal Brain Injury Coordinator Positions: A Culturally Secure Rehabilitation Service Initiative As Part Of A Clinical Trial, Elizabeth Armstrong, Kathy Mccoy, Rebecca Clinch, Maureen Merritt, Renee Speedy, Meaghan Mcallister, Kym Heine, Natalie Ciccone, Melanie Robinson, Julie Coffin

Research outputs 2014 to 2021

Brain injury, resulting from stroke and traumatic brain injury, is a common occurrence in Australia, with Aboriginal people affected at a significant rate and impact felt by individuals, families and communities. Access to brain injury rehabilitation services for Aboriginal people is reported to be often limited, with very little support outside the hospital environment. Our research involving Aboriginal brain injury survivors and their families to date has revealed that people often manage ‘on their own’ following such events. Following recommendations from survivors and their families, the Healing Right Way clinical trial, currently underway in Western Australia, has created the role …

Therapeutic Potential Of Mitophagy-Inducing Microflora Metabolite, Urolithin A For Alzheimer’S Disease, Dona Pamoda W. Jayatunga, Eugene Hone, Harjot Khaira, Taciana Lunelli, Harjinder Singh, Gilles J. Guillemin, Binosha Fernando, Manohar L. Garg, Giuseppe Verdile, Ralph N. Martins

Research outputs 2014 to 2021

Mitochondrial dysfunction including deficits of mitophagy is seen in aging and neuro-degenerative disorders including Alzheimer’s disease (AD). Apart from traditionally targeting amyloid beta (Aβ), the main culprit in AD brains, other approaches include investigating impaired mitochondrial pathways for potential therapeutic benefits against AD. Thus, a future therapy for AD may focus on novel candidates that enhance optimal mitochondrial integrity and turnover. Bi-oactive food components, known as nutraceuticals, may serve as such agents to combat AD. Uro-lithin A is an intestinal microbe-derived metabolite of a class of polyphenols, ellagitannins (ETs). Urolithin A is known to exert many health benefits. Its antioxidant, …

Hypogonadism Induced By Surgical Stress And Brain Trauma Is Reversed By Human Chorionic Gonadotropin In Male Rats: A Potential Therapy For Surgical And Tbi-Induced Hypogonadism?, Rastafa I. Geddes, Amita Kapoor, Kentaro Hayashi, Ryan Rauh, Marlyse Wehber, Quinn Bongers, Alex D. Jansen, Icelle M. Anderson, Gabrielle Farquhar, Sivan Vadakkadath-Meethal, Toni E. Ziegler, Craig S. Atwood

Research outputs 2014 to 2021

Introduction: Hypogonadotropic hypogonadism (HH) is an almost universal, yet underappreciated, endocrinological complication of traumatic brain injury (TBI). The goal of this study was to determine whether the developmental hormone human chorionic gonadotropin (hCG) treatment could reverse HH induced by a TBI. Methods: Plasma samples were collected at post-surgery/post-injury (PSD/PID) days -10, 1, 11, 19 and 29 from male Sprague-Dawley rats (5- to 6-month-old) that had undergone a Sham surgery (craniectomy alone) or CCI injury (craniectomy + bilateral moderate-to-severe CCI injury) and treatment with saline or hCG (400 IU/kg; i.m.) every other day. Results: Both Sham and CCI injury significantly decreased …

Help-Seeking For Mental Health Problems Among Older Adults With Chronic Disease: An Application Of The Theory Of Planned Behaviour, Claire Adams, Eyal Gringart, Natalie Strobel, Paul Masterman

Research outputs 2014 to 2021

Objective: Despite high risk for mental health problems, older adults with chronic diseases underutilise mental health services. This study applied the Theory of Planned Behaviour (TPB) to understand mental health help-seeking intentions among this population and identified factors which influence help-seeking intentions.

Method: We conducted a cross-sectional study with a non-clinical sample of 108 older adults aged 65 years or over, living with cardiovascular disease, respiratory disease, and/or type 2 diabetes. TPB variables (attitudes, subjective norms, and perceived behavioural control), intentions to seek help, and additional factors (past help-seeking behaviour, quality of life, and physical health) were assessed using standardised …

Effect Of Occupational Therapy Home Visit Discharge Planning On Participation After Stroke: Protocol For The Home Rehab Trial, Natasha A. Lannin, Lindy Clemson, Avril Drummond, Mandy Stanley, Leonid Churilov, Kate Laver, Sophie O'Keefe, Ian Cameron, Maria Crotty, Tim Usherwood, Nadine E. Andrew, Laura Jolliffe, Dominique A. Cadilhac

Research outputs 2014 to 2021

Introduction: After first stroke, the transition from rehabilitation to home can be confronting and fraught with challenges. Although stroke clinical practice guidelines recommend predischarge occupational therapy home visits to ensure safe discharge and provision of appropriate equipment, there is currently limited evidence to support this recommendation. Methods and analysis: The HOME Rehab trial is a national, multicentre, phase III randomised controlled trial with concealed allocation, blinded assessment and intention-to-treat analysis being conducted in Australia. The trial aim is to determine the effect and potential cost-effectiveness of an enhanced occupational therapy discharge planning intervention that involves pre and postdischarge home visits, …

Effect Of Goji Berry On The Formation Of Extracellular Senile Plaques Of Alzheimer's Disease, Warnakulasuriya M. A. D. B. Fernando, Ke Dong, Rosalie Durham, Regine Stockmann, Vijay Jayasena

Research outputs 2014 to 2021

BACKGROUND: Alzheimer's disease (AD) is the most common neurodegenerative disease and a major source of morbidity and mortality. Currently, no therapy nor drug can cure or modify AD progression, but recent studies suggest that nutritional compounds in certain foods can delay or prevent the onset of AD. Diets with high antioxidants is one of the examples which is believed to influence AD pathogenesis through direct effect on amyloid beta levels. Compared to other fruits and vegetables, goji berry (GB) has high levels of polyphenolic substances with antioxidant activities which have shown some positive effects on cognitive function while its mechanism …

The Intra-And Inter-Rater Reliability Of A Hip Rotation Range-Of-Motion Measurement Using A Smartphone Application In Academy Football (Soccer) Players, Paul Spork, James O’Brien, Morris Sepoetro, Maximilian Plachel, Thomas Stöggl

Research outputs 2014 to 2021

The clinical assessment of hip rotation range-of-motion (ROM) is important for managing hip and groin injuries in footballers. Previously published reliability studies on hip ROM have employed protocols that are difficult to replicate under everyday clinical conditions. This single trial, intra-and inter-rater reliability study included 41 male academy football (soccer) players, aged 14–15 years, from one European football academy. Passive hip internal rotation (IR) and external rotation (ER) ROM were measured in supine with hip and knee flexed to 90◦ . The ROM was determined using a smartphone application, with the smartphone attached to the lower leg. The tests were …

The Health Of Older Western Australians: The Role Of Age, Gender, Geographic Location, Psychological Distress, Perceived Health, Tobacco And Alcohol, Celia Wilkinson, Kim Clarke, Ros Sambell, Julie Dare, Stephen J. Bright

Research outputs 2014 to 2021

Purpose: Rates of drinking- and alcohol-related harms among older adults are increasing in most developed nations. The purpose of this paper was to explore the relationship among at-risk alcohol use, smoking, gender, geographical location, self-reported health and psychological well-being among Western Australians aged 65 years and older.

Design/methodology/approach: A secondary analysis was conducted of a cross-sectional survey that collected data from 7,804 West Australians aged 65 years and older between 2013 and 2015. Participants were categorised according to the following age groups: young-old (aged 65–74 years), older-old (aged 75–84 years) and oldest-old (aged 85+ years).

Findings: Results from a multinomial …